789 results on '"Petraroli, A"'
Search Results
152. Vascular Endothelial Growth Factors and Angiopoietins As New Players in Mastocytosis
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Marcella, Simone, primary, Petraroli, Angelica, additional, Braile, Mariantonia, additional, Parente, Roberta, additional, Ferrara, Anne Lise, additional, Galdiero, Maria Rosaria, additional, Modestino, Luca, additional, Cristinziano, Leonardo, additional, Rossi, Francesca Wanda, additional, Varricchi, Gilda, additional, Triggiani, Massimo, additional, de Paulis, Amato, additional, Spadaro, Giuseppe, additional, and Loffredo, Stefania, additional
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- 2021
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153. Authors’ Response to Letter to the Editor
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Marotta, Nicola, primary, Demeco, Andrea, additional, Marinaro, Cinzia, additional, Moggio, Lucrezia, additional, Pino, Ilaria, additional, Barletta, Marianna, additional, Petraroli, Annalisa, additional, and Ammendolia, Antonio, additional
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- 2021
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154. Psychology and hereditary angioedema: A systematic review
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Savarese, Livia, primary, Mormile, Ilaria, additional, Bova, Maria, additional, Petraroli, Angelica, additional, Maiello, Assunta, additional, Spadaro, Giuseppe, additional, and Freda, Maria Francesca, additional
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- 2021
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155. Human Macrophages and Monocytes Express Functional Na+/Ca2+ Exchangers 1 and 3
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Staiano, Rosaria I., primary, Granata, Francescopaolo, additional, Secondo, Agnese, additional, Petraroli, Angelica, additional, Loffredo, Stefania, additional, Annunziato, Lucio, additional, Triggiani, Massimo, additional, and Marone, Gianni, additional
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- 2012
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156. A Novel Mutation of the Luteinizing Hormone Receptor Gene in a Compound Heterozygote Child with Hypergonadotropic Hypogonadism
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Vottero, Alessandra, primary, Minari, Roberta, additional, Viani, Isabella, additional, Petraroli, Maddalena, additional, Bernasconi, Sergio, additional, and Ghizzoni, Lucia, additional
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- 2011
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157. PrP genotype in Sarda breed sheep and its relevance to scrapie
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Vaccari, G., Petraroli, R., Agrimi, U., Eleni, C., Perfetti, M. G., Di Bari, M. A., Morelli, L., Ligios, C., Busani, L., Nonno, R., and Di Guardo, G.
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- 2001
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158. Authors’ Response to Letter to the Editor
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Cinzia Marinaro, Lucrezia Moggio, Antonio Ammendolia, Andrea Demeco, Marianna Barletta, Ilaria Pino, Nicola Marotta, and Annalisa Petraroli
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Letter to the editor ,business.industry ,Rehabilitation ,MEDLINE ,Medicine ,Library science ,Physical Therapy, Sports Therapy and Rehabilitation ,business - Published
- 2021
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159. Envelope gp120 of HIV-1 binds to and activates human basophils
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Patella, Vincenzo, Florio, Giovanni, Petraroli, Angelica, Triggiani, Massimo, and Marone, Gianni
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- 2001
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160. Microstructural development and hardness of TiB 2–B 4C composite samples: Influence of consolidation temperature
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Srivatsan, T.S., Guruprasad, G., Black, D., Petraroli, M., Radhakrishnan, R., and Sudarshan, T.S.
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- 2006
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161. Icatibant treatment for acquired C1-inhibitor deficiency: a real-world observational study
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Zanichelli, A., Bova, M., Coerezza, A., Petraroli, A., Triggiani, M., and Cicardi, M.
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- 2012
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162. Rehabilitation in primary lateral sclerosis mimicking parkinsonism: A case report
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Moggio, Lucrezia, primary, Petraroli, Annalisa, additional, Marotta, Nicola, additional, Demeco, Andrea, additional, Pino, Ilaria, additional, Marinaro, Cinzia, additional, Barletta, Marianna, additional, and Ammendolia, Antonio, additional
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- 2020
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163. Rehabilitation of patients post-COVID-19 infection: a literature review
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Demeco, A., primary, Marotta, N., additional, Barletta, M., additional, Pino, I., additional, Marinaro, C., additional, Petraroli, A., additional, Moggio, L., additional, and Ammendolia, Antonio, additional
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- 2020
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164. Angiotensin-Converting Enzyme Inhibitor– Associated Angioedema: From Bed to Bench
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Carucci, L, primary, Bova, M, additional, Petraroli, A, additional, Ferrara, AL, additional, Sutic, A, additional, de Crescenzo, G, additional, Cordisco, G, additional, Margaglione, M, additional, Gambardella, J, additional, Spadaro, G, additional, Genovese, A, additional, and Loffredo, S, additional
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- 2020
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165. Gastrointestinal manifestations of angioedema: a potential area of misdiagnosis
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Mormile, Ilaria, primary, Cocchiaro, Antonio, additional, Bova, Maria, additional, Loffredo, Stefania, additional, de Paulis, Amato, additional, Spadaro, Giuseppe, additional, and Petraroli, Angelica, additional
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- 2020
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166. A myoferlin gain‐of‐function variant associates with a new type of hereditary angioedema
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Ariano, Anastasia, primary, D'Apolito, Maria, additional, Bova, Maria, additional, Bellanti, Francesco, additional, Loffredo, Stefania, additional, D'Andrea, Giovanna, additional, Intrieri, Mariano, additional, Petraroli, Angelica, additional, Maffione, Angela Bruna, additional, Spadaro, Giuseppe, additional, Santacroce, Rosa, additional, and Margaglione, Maurizio, additional
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- 2020
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167. The experience of living with a chronic disease in pediatrics from the mothers’ narratives: The Clinical Interview on Parental Sense of Grip on the Disease
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Savarese, Livia, primary, Freda, Maria Francesca, additional, De Luca Picione, Raffaele, additional, Dolce, Pasquale, additional, De Falco, Raffaella, additional, Alessio, Maria, additional, Cancian, Mauro, additional, Franzese, Adriana, additional, Guarino, Maria Domenica, additional, Perricone, Roberto, additional, Petraroli, Angelica, additional, Senter, Riccardo, additional, Traverso, Claudia, additional, Zanichelli, Andrea, additional, Zito, Eugenio, additional, and Bova, Maria, additional
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- 2020
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168. Silent Sinus Syndrome and Williams Syndrome: Two Rare Diseases Found in a Pediatric Patient
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Petraroli, Maddalena, primary, Riscassi, Sara, additional, Panigari, Arianna, additional, Maltese, Marilena, additional, and Esposito, Susanna, additional
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- 2020
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169. Impaired control of the contact system in hereditary angioedema with normal C1‐inhibitor
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Bova, Maria, primary, Suffritti, Chiara, additional, Bafunno, Valeria, additional, Loffredo, Stefania, additional, Cordisco, Giorgia, additional, Del Giacco, Stefano, additional, De Pasquale, Tiziana Maria Angela, additional, Firinu, Davide, additional, Margaglione, Maurizio, additional, Montinaro, Vincenzo, additional, Petraroli, Angelica, additional, Radice, Anna, additional, Brussino, Luisa, additional, Zanichelli, Andrea, additional, Zoli, Alessandra, additional, and Cicardi, Marco, additional
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- 2020
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170. Adult-onset macrophage activation syndrome treated by interleukin-1 inhibition.
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Casa, Francesca Della, Petraroli, Angelica, Mormile, Ilaria, Lagnese, Gianluca, Salvatore, Antonio Di, Rossi, Francesca Wanda, and Paulis, Amato de
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- 2023
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171. Secreted Phospholipases A2 in Hereditary Angioedema With C1-Inhibitor Deficiency
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Gérard Lambeau, Angelica Petraroli, Maria Bova, Maria Rosaria Galdiero, Marco Cicardi, Gianni Marone, Chiara Suffritti, Francescopaolo Granata, Henriette Farkas, Anne Lise Ferrara, Nóra Veszeli, Andrea Zanichelli, Gilda Varricchi, Francesco Borriello, Stefania Loffredo, Division of Clinical Immunology and Allergy, Università degli studi di Napoli Federico II, Faculty of Medicine, 3rd Department of Internal Medicine, Semmelweis University [Budapest], IRCCS-Istituti Clinici Scientifici Maugeri, University of Milan, Milan, Italy, Institut de pharmacologie moléculaire et cellulaire (IPMC), Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA), Loffredo, Stefania, Ferrara, Anne Lise, Bova, Maria, Borriello, Francesco, Suffritti, Chiara, Veszeli, Nóra, Petraroli, Angelica, Galdiero, Maria Rosaria, Varricchi, Gilda, Granata, Francescopaolo, Zanichelli, Andrea, Farkas, Henriette, Cicardi, Marco, Lambeau, Gérard, and Marone, Gianni
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lcsh:Immunologic diseases. Allergy ,0301 basic medicine ,Angiogenesis ,[SDV]Life Sciences [q-bio] ,Immunology ,Vascular permeability ,Angiopoietin ,Pharmacology ,angiogenesis ,03 medical and health sciences ,chemistry.chemical_compound ,Phospholipase A2 ,[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,Extracellular ,medicine ,Immunology and Allergy ,ComputingMilieux_MISCELLANEOUS ,Hereditary angioedema ,biology ,Chemistry ,bacterial infections and mycoses ,medicine.disease ,In vitro ,Pathophysiology ,3. Good health ,Vascular endothelial growth factor ,Angiogenesi ,030104 developmental biology ,biology.protein ,C1 inhibitor deficiency ,lcsh:RC581-607 ,angiopoietins ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology - Abstract
Background: Hereditary angioedema (HAE) caused by deficiency (type I) or dysfunction (type II) of the C1 inhibitor protein (C1-INH-HAE) is a disabling, potentially fatal condition characterized by recurrent episodes of swelling. We have recently found that patients with C1-INH-HAE have increased plasma levels of vascular endothelial growth factors (VEGFs) and angiopoietins (Angs), which have been associated with vascular permeability in several diseases. Among these and other factors, blood endothelial cells and vascular permeability can be modulated by extracellular or secreted phospholipases A2 (sPLA2s). Objective: We sought to investigate the enzymatic activity and biological functions of sPLA2 in patients with C1-INH-HAE. Methods: sPLA2 enzymatic activity was evaluated in the plasma from 109 adult patients with C1-INH-HAE and 68 healthy donors in symptom-free period and attacks. Plasma level of group IIA sPLA2 (hGIIA) protein was measured in selected samples. The effect of C1-INH-HAE plasma on endothelial permeability was examined in vitro using a vascular permeability assay. The role of hGIIA was determined using highly specific sPLA2 indole inhibitors. The effect of recombinant hGIIA on C1-INH activity was examined in vitro by functional assay. Results: Plasma sPLA2 activity and hGIIA levels are increased in symptom-free C1-INH-HAE patients compared to controls. sPLA2 activity negatively correlates with C1-INH protein level and function. C1-INH-HAE plasma increases endothelial permeability in vitro, and this effect is partially reverted by a specific hGIIA enzymatic inhibitor. Finally, recombinant hGIIA inhibits C1-INH activity in vitro. Conclusions: sPLA2 enzymatic activity (likely attributable to hGIIA), which is increased in C1-INH-HAE patients, can promote vascular permeability and impairs C1-INH activity. Our results may pave the way for investigating the functions of sPLA2s (in particular hGIIA) in the pathophysiology of C1-INH-HAE and may inform the development of new therapeutic targets.
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- 2018
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172. Simultaneous detection of lung fusions using a multiplex RT-PCR next generation sequencing-based approach: a multi-institutional research study
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Kelli Bramlett, Marjolijn J. L. Ligtenberg, Kazuko Sakai, Michel Bihl, Nicola Normanno, Alexander Boag, Cecily P. Vaughn, Susan Crocker, Harriet Feilotter, Andrea Mafficini, Varun Bagai, Bastiaan B J Tops, Anna Maria Rachiglio, José Carlos Machado, José Luis Costa, Aldo Scarpa, Ian A Cree, Hélène Blons, Delphine Le Corre, Orla Sheils, Rosella Petraroli, Pierre Laurent-Puig, Henriette M. Kurth, Roy R. L. Bastien, Federica Zito Marino, Astrid Hirschmann, Kazuto Nishio, Anne Reiman, Instituto de Investigação e Inovação em Saúde, Vaughn, Cp, Costa, Jl, Feilotter, He, Petraroli, R, Bagai, V, Rachiglio, Am, Zito Marino, F, and Et, Al.
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0301 basic medicine ,Male ,Cancer Research ,Lung Neoplasms ,Oncogene Proteins, Fusion ,Biopsy ,FFPE ,Fusion gene ,0302 clinical medicine ,Tumours of the digestive tract Radboud Institute for Molecular Life Sciences [Radboudumc 14] ,Multiplex ,Anaplastic Lymphoma Kinase ,Membrane Glycoproteins ,Reverse Transcriptase Polymerase Chain Reaction ,High-Throughput Nucleotide Sequencing ,Protein-Tyrosine Kinases ,lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,Detection ,Real-time polymerase chain reaction ,Oncology ,Technical Advance ,030220 oncology & carcinogenesis ,Adenocarcinoma ,Biomarker (medicine) ,Female ,Lung cancer ,Biology ,lcsh:RC254-282 ,03 medical and health sciences ,All institutes and research themes of the Radboud University Medical Center ,Cell Line, Tumor ,Proto-Oncogene Proteins ,Multiplex polymerase chain reaction ,Genetics ,ROS1 ,medicine ,Biomarkers, Tumor ,Humans ,Receptor, trkB ,Biomarker ,Gene fusions ,Next-generation sequencing ,Proto-Oncogene Proteins c-ret ,Receptor Protein-Tyrosine Kinases ,medicine.disease ,030104 developmental biology ,Cancer research ,Lymph Nodes ,Multiplex Polymerase Chain Reaction - Abstract
Background: Gene fusion events resulting from chromosomal rearrangements play an important role in initiation of lung adenocarcinoma. The recent association of four oncogenic driver genes, ALK, ROS1, RET, and NTRK1, as lung tumor predictive biomarkers has increased the need for development of up-to-date technologies for detection of these biomarkers in limited amounts of material. Methods: We describe here a multi-institutional study using the Ion AmpliSeq™ RNA Fusion Lung Cancer Research Panel to interrogate previously characterized lung tumor samples. Results: Reproducibility between laboratories using diluted fusion-positive cell lines was 100%. A cohort of lung clinical research samples from different origins (tissue biopsies, tissue resections, lymph nodes and pleural fluid samples) were used to evaluate the panel. We observed 97% concordance for ALK (28/30 positive; 71/70 negative samples), 95% for ROS1 (3/4 positive; 19/18 negative samples), and 93% for RET (2/1 positive; 13/14 negative samples) between the AmpliSeq assay and other methodologies. Conclusion: This methodology enables simultaneous detection of multiple ALK, ROS1, RET, and NTRK1 gene fusion transcripts in a single panel, enhanced by an integrated analysis solution. The assay performs well on limited amounts of input RNA (10ng) and offers an integrated single assay solution for detection of actionable fusions in lung adenocarcinoma, with potential savings in both cost and turn-around-time compared to the combination of all four assays by other methods. This work resulted from projects “Institute for Research and Innovation in Health Sciences” (POCI-01-0145-FEDER-007274), “GenomePT” (POCI-01-0145-FEDER-022184), “Advancing cancer research: from knowledge to application” (NORTE-01-0145-FEDER-000029) supported by COMPETE 2020 - Operational Programme for Competitiveness and Internationalisation (POCI), Norte Portugal Regional Programme (NORTE 2020), Lisboa Portugal Regional Operational Programme (Lisboa2020), Algarve Portugal Regional Operational Programme (CRESC Algarve2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF), and by FCT - Fundação para a Ciência e a Tecnologia (PTDC/DTP-PIC/2500/2014). This work was supported by a grant from the Associazione Italiana per la Ricerca sul Cancro (AIRC) to N. Normanno (Grant number: IG17135).
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- 2018
173. Emotional processes and stress in children affected by hereditary angioedema with C1-inhibitor deficiency: A multicenter, prospective study
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Gianni Marone, Adriana Franzese, Mauro Cancian, Matteo Zabotto, Paolo Valerio, Livia Savarese, Angelica Petraroli, Marco Cicardi, Maria Alessio, Maria Bova, Roberto Perricone, Eugenio Zito, Raffaele De Luca Picione, Claudia Traverso, Maria Francesca Freda, Maria Domenica Guarino, Riccardo Senter, Raffaella De Falco, Andrea Zanichelli, Savarese, Livia, Bova, Maria, DE FALCO, Raffaella, Domenica Guarino, Maria, DE LUCA PICIONE, Raffaele, Petraroli, Angelica, Senter, Riccardo, Traverso, Claudia, Zabotto, Matteo, Zanichelli, Andrea, Zito, Eugenio, Alessio, Maria, Cancian, Mauro, Cicardi, Marco, Franzese, Adriana, Perricone, Roberto, Marone, Gianni, Valerio, Paolo, and Freda, MARIA FRANCESCA
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Male ,Alexithymia ,medicine.medical_specialty ,Adolescent ,Alexithymia C1-inhibitor deficiency Children Hereditary angioedema Psychological factor Stress ,Emotions ,lcsh:Medicine ,Disease ,Anxiety ,Stress ,03 medical and health sciences ,0302 clinical medicine ,Surveys and Questionnaires ,Internal medicine ,medicine ,Humans ,Pharmacology (medical) ,Prospective Studies ,030212 general & internal medicine ,Psychological factor ,Child ,Prospective cohort study ,Children ,Genetics (clinical) ,Hereditary angioedema ,Type 1 diabetes ,C1-inhibitor deficiency ,business.industry ,Research ,lcsh:R ,Angioedemas, Hereditary ,General Medicine ,medicine.disease ,Settore MED/16 - Reumatologia ,Mood ,Rheumatoid arthritis ,Disease Progression ,Female ,medicine.symptom ,business ,Complement C1 Inhibitor Protein ,030217 neurology & neurosurgery - Abstract
Background Hereditary angioedema with C1-inhibitor deficiency (C1-INH-HAE) is characterized by recurrent edema of unpredictable frequency and severity. Stress, anxiety, and low mood are among the triggering factors most frequently reported. Impaired regulation and processing of emotions, also known as alexithymia, may influence outcomes. The aim of this study was to confirm the presence of alexithymia and stress in children with C1-INH-HAE, to determine whether they are also present in children affected by other chronic diseases, and to investigate their relationship with C1-INH-HAE severity. Data from children with C1-INH-HAE (n = 28) from four reference centers in Italy were compared with data from children with type 1 diabetes (T1D; n = 23) and rheumatoid arthritis (RA; n = 25). Alexithymia was assessed using the Alexithymia Questionnaire for Children scale; perceived stress was assessed using the Coddington Life Event Scale for Children (CLES-C). Results Mean age (standard deviation [SD]) in the C1-INH-HAE, T1D, and RA groups was 11.8 (3.3), 11.7 (2.9), and 11.1 (2.6) years, respectively. Mean C1-INH-HAE severity score was 5.9 (2.1), indicating moderate disease. Alexithymia scores were similar among disease groups and suggestive of difficulties in identifying and describing emotions; CLES-C scores tended to be worse in C1-INH-HAE children. C1-INH-HAE severity was found to correlate significantly and positively with alexithymia (p = 0.046), but not with perceived stress. Alexithymia correlated positively with perceived stress. Conclusions Alexithymia is common in children with chronic diseases. In C1-INH-HAE, it may result in increased perceived stress and act as a trigger of edema attacks. Comprehensive management of C1-INH-HAE children should consider psychological factors. Electronic supplementary material The online version of this article (10.1186/s13023-018-0871-x) contains supplementary material, which is available to authorized users.
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- 2018
174. Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with metformin (TOSCA.IT): a randomised, multicentre trial
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Vaccaro, O, Masulli, M, Nicolucci, A, Bonora, E, Del Prato, S, Maggioni, A, Rivellese, A, Squatrito, S, Giorda, C, Sesti, G, Mocarelli, P, Lucisano, G, Sacco, M, Signorini, S, Cappellini, F, Perriello, G, Babini, A, Lapolla, A, Gregori, G, Giordano, C, Corsi, L, Buzzetti, R, Clemente, G, Di Cianni, G, Iannarelli, R, Cordera, R, La Macchia, O, Zamboni, C, Scaranna, C, Boemi, M, Iovine, C, Lauro, D, Leotta, S, Dall'Aglio, E, Cannarsa, E, Tonutti, L, Pugliese, G, Bossi, A, Anichini, R, Dotta, F, Di Benedetto, A, Citro, G, Antenucci, D, Ricci, L, Giorgino, F, Santini, C, Gnasso, A, De Cosmo, S, Zavaroni, D, Vedovato, M, Consoli, A, Calabrese, M, di Bartolo, P, Fornengo, P, Riccardi, G, D'Angelo, F, Giansanti, R, Tanase, L, Lanari, L, Testa, I, Pancani, F, Ranchelli, A, Vagheggi, P, Scatona, A, Fontana, L, Laviola, L, Tarantino, L, Ippolito, C, Gigantelli, V, Manicone, M, Conte, E, Trevisan, R, Rota, R, Dodesini, A, Reggiani, G, Montesi, L, Mazzella, N, Forlani, G, Caselli, C, Di Luzio, R, Mazzotti, A, Aiello, A, Barrea, A, Musto, A, D'Amico, F, Sinagra, T, Longhitano, S, Trowpea, V, Sparti, M, Italia, S, Lisi, E, Grasso, G, Pezzino, V, Insalaco, F, Carallo, C, Scicchitano, C, De Franceschi, M, Calbucci, G, Ripani, R, Cuneo, G, Corsi, S, Romeo, F, Lesina, A, Comoglio, M, Bonetto, C, Robusto, A, Nada, E, Asprino, V, Cetraro, R, Impieri, M, Lucchese, G, Donnarumma, G, Tizio, B, Lenza, L, Paraggio, P, Tomasi, F, Dozio, N, Scalambra, E, Mannucci, E, Lamanna, C, Cignarelli, M, Macchia, O, Fariello, S, Sorrentino, M, Franzetti, I, Radin, R, Annunziata, F, Bonabello, L, Durante, A, Dolcino, M, Gallo, F, Mazzucchelli, C, Aleo, A, Melga, P, Briatore, L, Maggi, D, Storace, D, Cecoli, F, D'Ugo, E, Pupillo, M, Baldassarre, M, Salvati, F, Minnucci, A, De Luca, A, Zugaro, A, Santarelli, L, Bosco, A, Petrella, V, La Verghetta, G, D'Andrea, S, Giuliani, A, Polidoro, W, Sperandio, A, Sciarretta, F, Pezzella, A, Carlone, A, Potenziani, S, Venditti, C, Foffi, C, Carbone, S, Cipolloni, L, Moretti, C, Leto, G, Serra, R, Petrachi, F, Romano, I, Lacaria, E, Russo, L, Goretti, C, Sannino, C, Dolci, M, Bruselli, L, Mori, M, Baccetti, F, Del Freo, M, Cucinotta, D, Giunta, L, Ruffo, M, Cannizzaro, D, Pintaudi, B, Perrone, G, Pata, P, Ragonese, F, Lettina, G, Mancuso, T, Coppolino, A, Piatti, P, Monti, L, Stuccillo, M, Lucotti, P, Setola, M, Crippa, G, Loi, C, Oldani, M, Bottalico, M, Pellegata, B, Bonomo, M, Menicatti, L, Resi, V, Bertuzzi, F, Disoteo, E, Pizzi, G, Annuzzi, G, Capaldo, B, Nappo, R, Auciello, S, Turco, A, Costagliola, L, Corte, G, Vallefuoco, P, Nappi, F, Vitale, M, Cocozza, S, Ciano, O, Massimino, E, Garofalo, N, Avogaro, A, Guarneri, G, Fedele, D, Sartore, G, Chilelli, N, Burlina, S, Bonsembiante, B, Galluzzo, A, Torregrossa, V, Mancastroppa, G, Arsenio, L, Cioni, F, Caronna, S, Papi, M, Santeusanio, F, Calagreti, G, Timi, A, Tantucci, A, Marino, C, Ginestra, F, Di Biagio, R, Taraborelli, M, Miccoli, R, Bianchi, C, Garofolo, M, Politi, K, Penno, G, Livraga, S, Calzoni, F, Corsini, E, Tedeschi, A, Gagliano, M, Ippolito, G, Salutini, E, Cervellino, F, Natale, M, Salvatore, V, Zampino, A, Sinisi, R, Arcangeli, A, Zogheri, A, Guizzotti, S, Longo, R, Pellicano, F, Scolozzi, P, Termine, S, Luberto, A, Ballardini, G, Trojani, C, Mazzuca, P, Bruglia, M, Ciamei, M, Genghini, S, Zannoni, C, Rangel, G, Salvi, L, Zappaterreno, A, Cordone, S, Simonelli, P, Meggiorini, M, Frasheri, A, Di Pippo, C, Maglio, C, Mazzitelli, G, Rinaldi, M, Galli, A, Romano, M, D'Angelo, P, Suraci, C, Bacci, S, Palena, A, Genovese, S, Mancino, M, Rondinelli, M, Capone, F, Calabretto, E, Bulgheroni, M, Bucciarelli, L, Ceccarelli, E, Fondelli, C, Santacroce, C, Guarino, E, Nigi, L, Lalli, C, Di Vizia, G, Scarponi, M, Montani, V, Di Bernardino, P, Romagni, P, Dolcetti, K, Forte, E, Tamburo, L, Perin, P, Prinzis, T, Gruden, G, Bruno, G, Zucco, C, Perotta, M, Marena, S, Monsignore, S, Panero, F, Ponzi, F, Carpinteri, R, Casagrande, M, Coletti, M, Balini, A, Filopanti, M, Madaschi, S, Pulcina, A, Grimaldi, F, Venturini, G, Agus, S, Pagnutti, S, Guidotti, F, Cavarape, A, Cigolini, M, Pichiri, I, Brangani, C, Fainelli, G, Tomasetto, E, Zoppini, G, Galletti, A, Perrone, D, Capra, C, Bianchini, F, Ceseri, M, Di Nardo, B, Sasso, E, Bartolomei, B, Suliman, I, Fabbri, G, Romano, G, Maturo, N, Nunziata, G, Capobianco, G, De Simone, G, Villa, V, Rota, G, Pentangelo, C, Carbonara, O, Caiazzo, G, Cutolo, M, Sorrentino, T, Mastrilli, V, Amelia, U, Masi, S, Corigliano, G, Gaeta, I, Armentano, V, Calatola, P, Capuano, G, Angiulli, B, Auletta, P, Petraroli, E, Iodice, C, Agrusta, M, Vaccaro O., Masulli M., Nicolucci A., Bonora E., Del Prato S., Maggioni A. P., Rivellese A. A., Squatrito S., Giorda C. B., Sesti G., Mocarelli P., Lucisano G., Sacco M., Signorini S., Cappellini F., Perriello G., Babini A. C., Lapolla A., Gregori G., Giordano C., Corsi L., Buzzetti R., Clemente G., Di Cianni G., Iannarelli R., Cordera R., La Macchia O., Zamboni C., Scaranna C., Boemi M., Iovine C., Lauro D., Leotta S., Dall'Aglio E., Cannarsa E., Tonutti L., Pugliese G., Bossi A. C., Anichini R., Dotta F., Di Benedetto A., Citro G., Antenucci D., Ricci L., Giorgino F., Santini C., Gnasso A., De Cosmo S., Zavaroni D., Vedovato M., Consoli A., Calabrese M., di Bartolo P., Fornengo P., Riccardi G., D'Angelo F., Giansanti R., Tanase L., Lanari L., Testa I., Pancani F., Ranchelli A., Vagheggi P., Scatona A., Fontana L., Laviola L., Tarantino L., Ippolito C., Gigantelli V., Manicone M., Conte E., Trevisan R., Rota R., Dodesini A. R., Reggiani G. M., Montesi L., Mazzella N., Forlani G., Caselli C., Di Luzio R., Mazzotti A., Aiello A., Barrea A., Musto A., D'Amico F., Sinagra T., Longhitano S., Trowpea V., Sparti M., Italia S., Lisi E., Grasso G., Pezzino V., Insalaco F., Carallo C., Scicchitano C., De Franceschi M. S., Calbucci G., Ripani R., Cuneo G., Corsi S., Romeo F., Lesina A., Comoglio M., Bonetto C., Robusto A., Nada E., Asprino V., Cetraro R., Impieri M., Lucchese G., Donnarumma G., Tizio B., Lenza L., Paraggio P., Tomasi F., Dozio N., Scalambra E., Mannucci E., Lamanna C., Cignarelli M., Macchia O. L., Fariello S., Sorrentino M. R., Franzetti I., Radin R., Annunziata F., Bonabello L. A., Durante A., Dolcino M., Gallo F., Mazzucchelli C., Aleo A., Melga P., Briatore L., Maggi D., Storace D., Cecoli F., D'Ugo E., Pupillo M., Baldassarre M. P. A., Salvati F., Minnucci A., De Luca A., Zugaro A., Santarelli L., Bosco A., Petrella V., La Verghetta G. G., D'Andrea S., Giuliani A. E., Polidoro W. L., Sperandio A., Sciarretta F., Pezzella A., Carlone A., Potenziani S., Venditti C., Foffi C., Carbone S., Cipolloni L., Moretti C., Leto G., Serra R., Petrachi F., Romano I., Lacaria E., Russo L., Goretti C., Sannino C., Dolci M., Bruselli L., Mori M. L., Baccetti F., Del Freo M., Cucinotta D., Giunta L., Ruffo M. C., Cannizzaro D., Pintaudi B., Perrone G., Pata P., Ragonese F., Lettina G., Mancuso T., Coppolino A., Piatti P. M., Monti L., Stuccillo M., Lucotti P., Setola M., Crippa G. V., Loi C., Oldani M., Bottalico M. L., Pellegata B., Bonomo M., Menicatti L. S. M., Resi V., Bertuzzi F., Disoteo E. O., Pizzi G., Annuzzi G., Capaldo B., Nappo R., Auciello S. M., Turco A. A., Costagliola L., Corte G. D., Vallefuoco P., Nappi F., Vitale M., Cocozza S., Ciano O., Massimino E., Garofalo N., Avogaro A., Guarneri G., Fedele D., Sartore G., Chilelli N. C., Burlina S., Bonsembiante B., Galluzzo A., Torregrossa V., Mancastroppa G., Arsenio L., Cioni F., Caronna S., Papi M., Santeusanio F., Calagreti G., Timi A., Tantucci A., Marino C., Ginestra F., Di Biagio R., Taraborelli M., Miccoli R., Bianchi C., Garofolo M., Politi K. S., Penno G., Livraga S., Calzoni F., Mancastroppa G. L. F., Corsini E., Tedeschi A., Gagliano M. S., Ippolito G., Salutini E., Cervellino F., Natale M., Salvatore V., Zampino A., Sinisi R., Arcangeli A., Zogheri A., Guizzotti S., Longo R., Pellicano F., Scolozzi P., Termine S., Luberto A., Ballardini G., Trojani C., Mazzuca P., Bruglia M., Ciamei M., Genghini S., Zannoni C., Rangel G., Salvi L., Zappaterreno A., Cordone S., Simonelli P., Meggiorini M., Frasheri A., Di Pippo C., Maglio C., Mazzitelli G., Rinaldi M. E., Galli A., Romano M., D'Angelo P., Suraci C., Bacci S., Palena A. P., Genovese S., Mancino M., Rondinelli M., Capone F., Calabretto E., Bulgheroni M., Bucciarelli L., Ceccarelli E., Fondelli C., Santacroce C., Guarino E., Nigi L., Lalli C., Di Vizia G., Scarponi M., Montani V., Di Bernardino P., Romagni P., Dolcetti K., Forte E., Tamburo L., Perin P. C., Prinzis T., Gruden G., Bruno G., Zucco C., Perotta M., Marena S., Monsignore S., Panero F., Ponzi F., Carpinteri R., Casagrande M. L., Coletti M. F., Balini A., Filopanti M., Madaschi S., Pulcina A., Grimaldi F., Venturini G., Agus S., Pagnutti S., Guidotti F., Cavarape A., Cigolini M., Pichiri I., Brangani C., Fainelli G., Tomasetto E., Zoppini G., Galletti A., Perrone D., Capra C., Bianchini F., Ceseri M., Di Nardo B., Sasso E., Bartolomei B., Suliman I., Fabbri G., Romano G., Maturo N., Nunziata G., Capobianco G., De Simone G., Villa V., Rota G., Pentangelo C., Carbonara O., Caiazzo G., Cutolo M., Sorrentino T., Mastrilli V., Amelia U., Masi S., Corigliano G., Gaeta I., Armentano V., Calatola P., Capuano G., Angiulli B., Auletta P., Petraroli E., Iodice C. E., Agrusta M., Vaccaro, O, Masulli, M, Nicolucci, A, Bonora, E, Del Prato, S, Maggioni, A, Rivellese, A, Squatrito, S, Giorda, C, Sesti, G, Mocarelli, P, Lucisano, G, Sacco, M, Signorini, S, Cappellini, F, Perriello, G, Babini, A, Lapolla, A, Gregori, G, Giordano, C, Corsi, L, Buzzetti, R, Clemente, G, Di Cianni, G, Iannarelli, R, Cordera, R, La Macchia, O, Zamboni, C, Scaranna, C, Boemi, M, Iovine, C, Lauro, D, Leotta, S, Dall'Aglio, E, Cannarsa, E, Tonutti, L, Pugliese, G, Bossi, A, Anichini, R, Dotta, F, Di Benedetto, A, Citro, G, Antenucci, D, Ricci, L, Giorgino, F, Santini, C, Gnasso, A, De Cosmo, S, Zavaroni, D, Vedovato, M, Consoli, A, Calabrese, M, di Bartolo, P, Fornengo, P, Riccardi, G, D'Angelo, F, Giansanti, R, Tanase, L, Lanari, L, Testa, I, Pancani, F, Ranchelli, A, Vagheggi, P, Scatona, A, Fontana, L, Laviola, L, Tarantino, L, Ippolito, C, Gigantelli, V, Manicone, M, Conte, E, Trevisan, R, Rota, R, Dodesini, A, Reggiani, G, Montesi, L, Mazzella, N, Forlani, G, Caselli, C, Di Luzio, R, Mazzotti, A, Aiello, A, Barrea, A, Musto, A, D'Amico, F, Sinagra, T, Longhitano, S, Trowpea, V, Sparti, M, Italia, S, Lisi, E, Grasso, G, Pezzino, V, Insalaco, F, Carallo, C, Scicchitano, C, De Franceschi, M, Calbucci, G, Ripani, R, Cuneo, G, Corsi, S, Romeo, F, Lesina, A, Comoglio, M, Bonetto, C, Robusto, A, Nada, E, Asprino, V, Cetraro, R, Impieri, M, Lucchese, G, Donnarumma, G, Tizio, B, Lenza, L, Paraggio, P, Tomasi, F, Dozio, N, Scalambra, E, Mannucci, E, Lamanna, C, Cignarelli, M, Macchia, O, Fariello, S, Sorrentino, M, Franzetti, I, Radin, R, Annunziata, F, Bonabello, L, Durante, A, Dolcino, M, Gallo, F, Mazzucchelli, C, Aleo, A, Melga, P, Briatore, L, Maggi, D, Storace, D, Cecoli, F, D'Ugo, E, Pupillo, M, Baldassarre, M, Salvati, F, Minnucci, A, De Luca, A, Zugaro, A, Santarelli, L, Bosco, A, Petrella, V, La Verghetta, G, D'Andrea, S, Giuliani, A, Polidoro, W, Sperandio, A, Sciarretta, F, Pezzella, A, Carlone, A, Potenziani, S, Venditti, C, Foffi, C, Carbone, S, Cipolloni, L, Moretti, C, Leto, G, Serra, R, Petrachi, F, Romano, I, Lacaria, E, Russo, L, Goretti, C, Sannino, C, Dolci, M, Bruselli, L, Mori, M, Baccetti, F, Del Freo, M, Cucinotta, D, Giunta, L, Ruffo, M, Cannizzaro, D, Pintaudi, B, Perrone, G, Pata, P, Ragonese, F, Lettina, G, Mancuso, T, Coppolino, A, Piatti, P, Monti, L, Stuccillo, M, Lucotti, P, Setola, M, Crippa, G, Loi, C, Oldani, M, Bottalico, M, Pellegata, B, Bonomo, M, Menicatti, L, Resi, V, Bertuzzi, F, Disoteo, E, Pizzi, G, Annuzzi, G, Capaldo, B, Nappo, R, Auciello, S, Turco, A, Costagliola, L, Corte, G, Vallefuoco, P, Nappi, F, Vitale, M, Cocozza, S, Ciano, O, Massimino, E, Garofalo, N, Avogaro, A, Guarneri, G, Fedele, D, Sartore, G, Chilelli, N, Burlina, S, Bonsembiante, B, Galluzzo, A, Torregrossa, V, Mancastroppa, G, Arsenio, L, Cioni, F, Caronna, S, Papi, M, Santeusanio, F, Calagreti, G, Timi, A, Tantucci, A, Marino, C, Ginestra, F, Di Biagio, R, Taraborelli, M, Miccoli, R, Bianchi, C, Garofolo, M, Politi, K, Penno, G, Livraga, S, Calzoni, F, Corsini, E, Tedeschi, A, Gagliano, M, Ippolito, G, Salutini, E, Cervellino, F, Natale, M, Salvatore, V, Zampino, A, Sinisi, R, Arcangeli, A, Zogheri, A, Guizzotti, S, Longo, R, Pellicano, F, Scolozzi, P, Termine, S, Luberto, A, Ballardini, G, Trojani, C, Mazzuca, P, Bruglia, M, Ciamei, M, Genghini, S, Zannoni, C, Rangel, G, Salvi, L, Zappaterreno, A, Cordone, S, Simonelli, P, Meggiorini, M, Frasheri, A, Di Pippo, C, Maglio, C, Mazzitelli, G, Rinaldi, M, Galli, A, Romano, M, D'Angelo, P, Suraci, C, Bacci, S, Palena, A, Genovese, S, Mancino, M, Rondinelli, M, Capone, F, Calabretto, E, Bulgheroni, M, Bucciarelli, L, Ceccarelli, E, Fondelli, C, Santacroce, C, Guarino, E, Nigi, L, Lalli, C, Di Vizia, G, Scarponi, M, Montani, V, Di Bernardino, P, Romagni, P, Dolcetti, K, Forte, E, Tamburo, L, Perin, P, Prinzis, T, Gruden, G, Bruno, G, Zucco, C, Perotta, M, Marena, S, Monsignore, S, Panero, F, Ponzi, F, Carpinteri, R, Casagrande, M, Coletti, M, Balini, A, Filopanti, M, Madaschi, S, Pulcina, A, Grimaldi, F, Venturini, G, Agus, S, Pagnutti, S, Guidotti, F, Cavarape, A, Cigolini, M, Pichiri, I, Brangani, C, Fainelli, G, Tomasetto, E, Zoppini, G, Galletti, A, Perrone, D, Capra, C, Bianchini, F, Ceseri, M, Di Nardo, B, Sasso, E, Bartolomei, B, Suliman, I, Fabbri, G, Romano, G, Maturo, N, Nunziata, G, Capobianco, G, De Simone, G, Villa, V, Rota, G, Pentangelo, C, Carbonara, O, Caiazzo, G, Cutolo, M, Sorrentino, T, Mastrilli, V, Amelia, U, Masi, S, Corigliano, G, Gaeta, I, Armentano, V, Calatola, P, Capuano, G, Angiulli, B, Auletta, P, Petraroli, E, Iodice, C, Agrusta, M, Vaccaro O., Masulli M., Nicolucci A., Bonora E., Del Prato S., Maggioni A. P., Rivellese A. A., Squatrito S., Giorda C. B., Sesti G., Mocarelli P., Lucisano G., Sacco M., Signorini S., Cappellini F., Perriello G., Babini A. C., Lapolla A., Gregori G., Giordano C., Corsi L., Buzzetti R., Clemente G., Di Cianni G., Iannarelli R., Cordera R., La Macchia O., Zamboni C., Scaranna C., Boemi M., Iovine C., Lauro D., Leotta S., Dall'Aglio E., Cannarsa E., Tonutti L., Pugliese G., Bossi A. C., Anichini R., Dotta F., Di Benedetto A., Citro G., Antenucci D., Ricci L., Giorgino F., Santini C., Gnasso A., De Cosmo S., Zavaroni D., Vedovato M., Consoli A., Calabrese M., di Bartolo P., Fornengo P., Riccardi G., D'Angelo F., Giansanti R., Tanase L., Lanari L., Testa I., Pancani F., Ranchelli A., Vagheggi P., Scatona A., Fontana L., Laviola L., Tarantino L., Ippolito C., Gigantelli V., Manicone M., Conte E., Trevisan R., Rota R., Dodesini A. R., Reggiani G. M., Montesi L., Mazzella N., Forlani G., Caselli C., Di Luzio R., Mazzotti A., Aiello A., Barrea A., Musto A., D'Amico F., Sinagra T., Longhitano S., Trowpea V., Sparti M., Italia S., Lisi E., Grasso G., Pezzino V., Insalaco F., Carallo C., Scicchitano C., De Franceschi M. S., Calbucci G., Ripani R., Cuneo G., Corsi S., Romeo F., Lesina A., Comoglio M., Bonetto C., Robusto A., Nada E., Asprino V., Cetraro R., Impieri M., Lucchese G., Donnarumma G., Tizio B., Lenza L., Paraggio P., Tomasi F., Dozio N., Scalambra E., Mannucci E., Lamanna C., Cignarelli M., Macchia O. L., Fariello S., Sorrentino M. R., Franzetti I., Radin R., Annunziata F., Bonabello L. A., Durante A., Dolcino M., Gallo F., Mazzucchelli C., Aleo A., Melga P., Briatore L., Maggi D., Storace D., Cecoli F., D'Ugo E., Pupillo M., Baldassarre M. P. A., Salvati F., Minnucci A., De Luca A., Zugaro A., Santarelli L., Bosco A., Petrella V., La Verghetta G. G., D'Andrea S., Giuliani A. E., Polidoro W. L., Sperandio A., Sciarretta F., Pezzella A., Carlone A., Potenziani S., Venditti C., Foffi C., Carbone S., Cipolloni L., Moretti C., Leto G., Serra R., Petrachi F., Romano I., Lacaria E., Russo L., Goretti C., Sannino C., Dolci M., Bruselli L., Mori M. L., Baccetti F., Del Freo M., Cucinotta D., Giunta L., Ruffo M. C., Cannizzaro D., Pintaudi B., Perrone G., Pata P., Ragonese F., Lettina G., Mancuso T., Coppolino A., Piatti P. M., Monti L., Stuccillo M., Lucotti P., Setola M., Crippa G. V., Loi C., Oldani M., Bottalico M. L., Pellegata B., Bonomo M., Menicatti L. S. M., Resi V., Bertuzzi F., Disoteo E. O., Pizzi G., Annuzzi G., Capaldo B., Nappo R., Auciello S. M., Turco A. A., Costagliola L., Corte G. D., Vallefuoco P., Nappi F., Vitale M., Cocozza S., Ciano O., Massimino E., Garofalo N., Avogaro A., Guarneri G., Fedele D., Sartore G., Chilelli N. C., Burlina S., Bonsembiante B., Galluzzo A., Torregrossa V., Mancastroppa G., Arsenio L., Cioni F., Caronna S., Papi M., Santeusanio F., Calagreti G., Timi A., Tantucci A., Marino C., Ginestra F., Di Biagio R., Taraborelli M., Miccoli R., Bianchi C., Garofolo M., Politi K. S., Penno G., Livraga S., Calzoni F., Mancastroppa G. L. F., Corsini E., Tedeschi A., Gagliano M. S., Ippolito G., Salutini E., Cervellino F., Natale M., Salvatore V., Zampino A., Sinisi R., Arcangeli A., Zogheri A., Guizzotti S., Longo R., Pellicano F., Scolozzi P., Termine S., Luberto A., Ballardini G., Trojani C., Mazzuca P., Bruglia M., Ciamei M., Genghini S., Zannoni C., Rangel G., Salvi L., Zappaterreno A., Cordone S., Simonelli P., Meggiorini M., Frasheri A., Di Pippo C., Maglio C., Mazzitelli G., Rinaldi M. E., Galli A., Romano M., D'Angelo P., Suraci C., Bacci S., Palena A. P., Genovese S., Mancino M., Rondinelli M., Capone F., Calabretto E., Bulgheroni M., Bucciarelli L., Ceccarelli E., Fondelli C., Santacroce C., Guarino E., Nigi L., Lalli C., Di Vizia G., Scarponi M., Montani V., Di Bernardino P., Romagni P., Dolcetti K., Forte E., Tamburo L., Perin P. C., Prinzis T., Gruden G., Bruno G., Zucco C., Perotta M., Marena S., Monsignore S., Panero F., Ponzi F., Carpinteri R., Casagrande M. L., Coletti M. F., Balini A., Filopanti M., Madaschi S., Pulcina A., Grimaldi F., Venturini G., Agus S., Pagnutti S., Guidotti F., Cavarape A., Cigolini M., Pichiri I., Brangani C., Fainelli G., Tomasetto E., Zoppini G., Galletti A., Perrone D., Capra C., Bianchini F., Ceseri M., Di Nardo B., Sasso E., Bartolomei B., Suliman I., Fabbri G., Romano G., Maturo N., Nunziata G., Capobianco G., De Simone G., Villa V., Rota G., Pentangelo C., Carbonara O., Caiazzo G., Cutolo M., Sorrentino T., Mastrilli V., Amelia U., Masi S., Corigliano G., Gaeta I., Armentano V., Calatola P., Capuano G., Angiulli B., Auletta P., Petraroli E., Iodice C. E., and Agrusta M.
- Abstract
Background The best treatment option for patients with type 2 diabetes in whom treatment with metformin alone fails to achieve adequate glycaemic control is debated. We aimed to compare the long-term effects of pioglitazone versus sulfonylureas, given in addition to metformin, on cardiovascular events in patients with type 2 diabetes. Methods TOSCA.IT was a multicentre, randomised, pragmatic clinical trial, in which patients aged 50–75 years with type 2 diabetes inadequately controlled with metformin monotherapy (2–3 g per day) were recruited from 57 diabetes clinics in Italy. Patients were randomly assigned (1:1), by permuted blocks randomisation (block size 10), stratified by site and previous cardiovascular events, to add-on pioglitazone (15–45 mg) or a sulfonylurea (5–15 mg glibenclamide, 2–6 mg glimepiride, or 30–120 mg gliclazide, in accordance with local practice). The trial was unblinded, but event adjudicators were unaware of treatment assignment. The primary outcome, assessed with a Cox proportional-hazards model, was a composite of first occurrence of all-cause death, non-fatal myocardial infarction, non-fatal stroke, or urgent coronary revascularisation, assessed in the modified intention-to-treat population (all randomly assigned participants with baseline data available and without any protocol violations in relation to inclusion or exclusion criteria). This study is registered with ClinicalTrials.gov, number NCT00700856. Findings Between Sept 18, 2008, and Jan 15, 2014, 3028 patients were randomly assigned and included in the analyses. 1535 were assigned to pioglitazone and 1493 to sulfonylureas (glibenclamide 24 [2%], glimepiride 723 [48%], gliclazide 745 [50%]). At baseline, 335 (11%) participants had a previous cardiovascular event. The study was stopped early on the basis of a futility analysis after a median follow-up of 57·3 months. The primary outcome occurred in 105 patients (1·5 per 100 person-years) who were given pioglitazone and 108 (1·5 p
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- 2017
175. RUOLO DELL’HAEMOHILUS PARAINFLUENZAE NELLE RIACUTIZZAZIONI DELLE BPCO.
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P. Barbaro, C. Petraroli, B. Rogolino, D. Sergi, G. Agati, and A. Scaramozzino
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Microbiology ,QR1-502 - Published
- 2003
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176. Fetal Sex Identification in Maternal Plasma by Means of Short Tandem Repeats on Chromosome X
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Vecchione, Gennaro, Tomaiuolo, Michela, Sarno, Michelina, Colaizzo, Donatella, Petraroli, Rosella, Matteo, Maria, Greco, Pantaleo, Grandone, Elvira, and Margaglione, Maurizio
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- 2008
177. loco qui dicitur Lauri nel territorio di Montasola (RI)
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Petraroli, Viviana
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Montasola Sabina Rieti - Published
- 2019
178. L'insediamento di Caprignano
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Petraroli, Viviana
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Caprignano ,Rieti ,Sabina - Published
- 2019
179. Differentiation of monocytes into macrophages induces the upregulation of histamine H1 receptor
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Triggiani, Massimo, Petraroli, Angelica, Loffredo, Stefania, Frattini, Annunziata, Granata, Francescopaolo, Morabito, Paolo, Staiano, Rosaria Ilaria, Secondo, Agnese, Annunziato, Lucio, and Marone, Gianni
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- 2007
180. Phenotypic and Functional Heterogeneity of Low-Density and High-Density Human Lung Macrophages
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Gilda Varricchi, Giulia Scalia, Francescopaolo Granata, Barbara Balestrieri, Massimo Triggiani, Chiara Cardamone, Paolo Morabito, Angelica Petraroli, and Stefania Loffredo
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Lipopolysaccharide ,QH301-705.5 ,Population ,Medicine (miscellaneous) ,Inflammation ,Article ,General Biochemistry, Genetics and Molecular Biology ,lung ,Cancer ,IL-10 ,IL-12 ,IL-6 ,Lung ,Macrophages ,Monocytes ,TNF-α ,chemistry.chemical_compound ,Parenchyma ,medicine ,cancer ,Biology (General) ,education ,education.field_of_study ,CD40 ,biology ,lipopolysaccharide ,Molecular biology ,macrophages ,Interleukin 10 ,medicine.anatomical_structure ,chemistry ,biology.protein ,Interleukin 12 ,medicine.symptom ,monocytes - Abstract
Background: Pulmonary macrophages are a highly heterogeneous cell population distributed in different lung compartments. Methods: We separated two subpopulations of macrophages from human lung parenchyma according to flotation over density gradients. Results: Two-thirds 65.4% of the lung macrophages have a density between 1.065 and 1.078 (high-density macrophages: HDMs), and the remaining one-third (34.6) had a density between 1.039 and 1.052 (low-density macrophages: LDMs). LDMs had a larger area (691 vs. 462 μm2) and cell perimeter (94 vs. 77 μm) compared to HDMs. A significantly higher percentage of HDMs expressed CD40, CD45, and CD86 compared to LDMs. In contrast, a higher percentage of LDMs expressed the activation markers CD63 and CD64. The release of TNF-α, IL-6, IL-10 and IL-12 induced by lipopolysaccharide (LPS) was significantly higher in HDMs than in LDMs. Conclusion: The human lung contains two subpopulations of macrophages that differ in buoyancy, morphometric parameters, surface marker expression and response to LPS. These subpopulations of macrophages probably play distinct roles in lung inflammation and immune responses.
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- 2021
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181. Polymorphisms of the prion protein gene in Italian patients with Creutzfeldt-Jakob disease
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Salvatore, Mirella, Genuardi, Maurizio, Petraroli, Rosella, Masullo, Carlo, D'Alessandro, Marco, and Pocchiari, Maurizio
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- 1994
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182. Fourth meeting of the European Neurological Society 25–29 June 1994 Barcelona, Spain: Abstracts of Symposia and free communications
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Harms, L., Bock, A., JÄnisch, W., Valdueza, J., Weber, J., Link, I., De Keyser, J., Goossens, A., Wilczak, N., Vedeler, C., Bjorge, L., Uvestad, E., Conti, G., Williams, K., Ginsberg, L., Rafique, S., Rapoport, S. I., Gershfeld, N. L., De La Meilleure, G., Crevits, L., Faiss, J. H., Heye, N., Blanke, J., Sackmann, A., Kastrup, O., Doornbos, R., van der Worp, H. B., Kappelle, L. J., Bar, P. R., Davie, C. A., Barker, G. J., Brenton, D., Miller, D. H., Thompson, A. J., Block, F., Schwarz, M., Delodovici, L., Baruzzi, F., Bonaldi, G., Dario, A., Marra, A., Mercuri, A., Dworzak, F., Cavallari, P., Confalonieri, P., Zuffi, M., Antozzi, C., Cornelio, F., Baldissera, F., Chassande, B., Ameri, A., Eymard, B., Poisson, M., Vérier, A., Brunet, P., Congia, S., Murgia, P. L., Cannas, A., Borghero, G., Uselli, S., Mellino, G., Ferrai, R., Lampis, R., Massa, R., Muzzetto, B., Giannini, F., Rossi, S., Cioni, R., d'Aniello, C., Guarneri, A., Battistini, N., Ceriani, F., Del Santo, A., Poloni, M., Campo, J. F., Iglesias, F., Guitera, M. V., Farinas, C., Pascual, J., Leno, C., Berciano, J., Thorpe, I. W., Kendall, B. E., McDonald, W. I., Moulignier, A., Dromer, F., Baudrimont, M., Dupont, B., Gozlan, J., El Amrani, M., Petit, J. C., Roullet, E., Sterzi, R., Causaran, R., Protti, A., Riva, M., Erminio, F., Arena, O., Villa, F., Maccagnano, E., Miletta, M., Spinelli, F., Ben-Hur, T., Weidenfeldl, J., Rao, N. S., Chari, C. C., Laforet, P., Matheron, S., Adams, D., Chemouilli, Ph., Desi, M., Said, G., Davous, P., Lionnet, F., Pulik, M., Genet, P., Rozenberg, F., Cartier, L. M., Castillo, J. L., Cea, J. G., Villagra, R., de Saint Martin, L., Mahieux, F., Manifacier, M. J., Mattos, K., Queiros, C., Publio, L., Vinhas, V., PeÇanha-Martins, A. 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A., Nieto, M., Noya, M., Oller, L., Kiteva-Trencevska, G., Delgado, M. R., Liu, H., Luengo, A., Parra, J., Colas, J., Fernandez, M. J., Manzanares, R., Kornhuber, M. E., Malashkhia, V., Orkodashili, G., Martinez, M., Bonaventura, I., Porta, G., Martinez, I., Fernandez, A., Aguilar, M., Masnou, P., Drouet, A., Dreyfus, M., Cartron, J., Morel-Kopp, M. C., Tchernia, G., Kaplan, C., Lammers, M. W., Hekster, Y. A., Keyser, A., Meinardi, H., Renier, W. O., Boon, P. A. J. M., Have, M. D., Kint, B., Cruz, P., Cadilha, A., Almeida, R., Goncalves, M., Pimenta, M., Ramos, L. M. P., Polder, T. W., Broere, C. A., Polman, L., Rother, I., Rother, M., Schlaug, G., Arnold, S., Holthausen, H., Wunderlich, G., Ebner, A., Luders, H., Witte, O. W., Seitz, R. J., Serra, L. L., Gallicchio, B., Rotondi, F., Wieshmann, U., Meierkord, H., Sabev, K., Di Carlo, V., Gueguen, B., Derouesné, Ch., Ancri, D., Bourdel, M. C., Guillou, S., Aliaga, R., Chornet, M. A., Rodrigo, A., Pascual, A. Pascual -Leone, Catala, M. D., Pascual-Leone, A., Benbadis, S. R., Dinner, D. S., Chelune, G. J., Lüders, H. O., Piedmonte, M. R., Blanco, T., Lopez, M. P., Romero, B., Deltoro, A., Pascual, A., Pascual, Leone, Bolgert, F., Josse, M. O., Tassan, P., Touze, E., Laplane, D., Godenberg, F., Brizioli, E., Del Gobbo, M., Pelliccioni, G., Scarpino, O., Durak, H., Damlacik, G., Tunca, Z., Fidaner, H., Yurekli, Y., Yemez, B., Kaygisiz, A., Anllo, E. A., Esperet, E., Giovagnoli, A. R., Casazza, M., Spreafico, R., Avanzini, G., Mascheroni, S., Vecchio, I., Tornali, C., Antonuzzo, A., Grasso, A. A., Bella, R., Pennisi, G., Raffaele, R., Broeckx, J., Schildermans, F., Hospers, W., Deberdt, W., Carney, J. M., Aksenova, M., Chen, M. S., Juncadella, M., Busquets, N., De la Fuente, I., Rodriguez, A., Rubio, F., Soler, R., Khati, C., Pillon, B., Deweer, B., Malapani, C., Malichard, N., Dubois, B., Rancurel, G., Lopez, D. L., Jungreia, G., DeKosky, S. T., Boiler, F., Weiller, C., Rijntjes, M., Mueller, S. P., Maguire, E. A., Burke, E. T., Staunton, H., Phillips, J., Rousseaux, M., Pena, J., Bertran, I., Santacruz, P., Lopez, R., Catafau, A., Lomena, F., Blesa, R., Rampello, L., Nicoletti, A., Cabaret, M., Lesoin, F., Steinling, M., Tournev, I., Maier-Hauff, K., Schroeder, M., Wolf, A., Cochin, J. P., Noel, I., Augustin, P., Auzou, P., Hannequin, D., Maria, V., Lopez-Bresnahan, Danielle, D. M., Antin-Ozerkis B. A., Bartels, E., Rodiek, S. O., Flugel, K. A., Campos, D. M., Salas-Puig, J., Del Rio, J. Sanhez, Vidal, J. A., Lahoz, C. H., Eraksoy, M., Barlas, O., Barlas, M., Bayindir, C., Ozcan, H., Birbamer, G., Gerstenbrand, F., Felber, S., Luz, G., Aichner, F., Seidel, G., Kaps, M., Hutzelmann, A., Gerriets, T., Kruggel, F., Martin, P. J., Gaunt, M. E., Abbot, R. J., Naylor, A. R., Meary, E., Dilouya, A., Meder, J. F., De Recondo, J., Lebtahi, R., Neff, K. W., Meairs, S., Viola, S., Matta, E., Aquilone, L., Rise, I. R., Authier, F. J., Kondo, H., Ghnassia, R. T., Degos, J. D., Gherardi, R. K., Bardoni A., Ciafaloni E., Comi G. P., Bresolin N., Robotti M., Moggio M., Rigoletto C., Roses A., Scarlato G., Castelli, E., Turconi, A., Bresolin, N., Perani, D., Felisari, G., Chariot, P., de Pinieux, G., Astier, A., Jacotot, B., Gherardi, R., Fischer-Gagnepain, V., Louboutin, J. P., Crespo, F., Florea-Strat, A., Fromont, G., Sabourin, J. -C., Gonano, E. -F., Moroni, I., Prelle, A., Iannaccone, S., Quattrini, A., deRino, F., Sessa, M., Golzi, V., Smirne, S., Nemni, R., Turpin, J. C., Lucotte, G., Jacobs, S. C. J. M., Willems, P. W. A., Bootsma, A. L., Lasa, A., Calaf, M., Baiget, M., Gallano, B., Fichter-Gagnepain, V., Mazzucchelli, F., D'Angelo, M. G., Velicogna, M., Bet, L., Comi, G. P., Bordoni, A., Gonano, E. F., Bazzi, P., Rapuzzi, S., Moggio, M., Fagiolari, G., Ciscato, P., Messina, A., Battistel, A., Ryniewicz, B., Sangla, I., Desnuelle, C., Paquis, V., Cozzone, P. J., Bendahan, D., Sturenburg, H. J., Kohncke, G., Castellli, E., Linssen, W., Stegeman, D., Binkhorst, R., Notermans, S., Jaspert, A., Fahsold, R., de Munain, A. Lopez, Cobo, A., Martorell, L., Poza, J. J., Navarrete Palau, D., Emparanza, J. I., Sanchez-Roy, R., Vilchez, J. J., Hernandez, M., Tena, J. Garcia, Perla, C., Koutroumanidis, M., Papathanasopoulos, P., Papadimitriou, A., Papapetropoulos, T. H., Divari, R., Hadjigeorgiou, G. M., Anastasopoulos, I., Sansone, V., Rotondo, G., Meola, G., Rigoletto, C., Messina, S., Szwabowska-Orzeszko, E., Jozwiak, S., Michalowicz, R., Szaplyko, W., Petrella, M. A., Della Marca, G., Masullo, G., Mennuni, G. F., Kompf, D., Wascher, E., Verleger, R., Kaido, M., Soga, F., Toyooka, H., Bayon, C., Rubio, J., Carlomagno, S., Parlato, V., Santoro, A., Lavarone, A., Bonavita, V., Pentore, R., Venneri, A., Pasquier, F., Lebert, F., Grymonprez, L., Lefebvre, C., Van der Linden, M., Derouesné, C., Renault, B., Lacomblez, L., Homeyer, P., Ouss, L., Neuman, E., Malbezin, M., Barrandon, S., Guez, D., Stevens, M., van Swieten, J. C., Franke, C. L., Sanchez, A., Castellvirel, S., Mila, M., Jimenez, D., Pallesta, F., Ruiz, P. J. Garcia, Barrio, A., Barroso, T., Benitez, J., de Yebenes, J. Garcia, Manubens, J. M., Martinez-Lage, J. M., Larumbe, R., Muruzabal, J., Lacruz, F., Quesada, Pedro, Gallego, J., Ferini-Strambi, L., Marcone, A., Garancini, P., Tedesi, B., Jacob, B., Rozewicz, L., Langdon, D., Davie, C., Ron, M., Thompson, A., Koepp, M. J., Hansen, M. L., Guldin, B., Pressler, R. M., Ried, S., Scholz, C., Monaco, F., Gianelli, M., Schiavalla, M. P., Naldi, P., Cantello, R., Torta, R., Verze, L., Mutani, R., Knott, H., Ferbert, A., Schulze-Bonhage, A., Aust, W., Di Mascio, R., Marchioli, R., Vitullo, F., Di Pasquale, A., Sciulli, L., Kramer, V., Tognoni, G., Santacruz, P., Lopez, R., Marti, M. J., Charques, I., Catafau, A., Lomeila, F., Peila, J., Bertran, I., Blesa, R., Krendel, D. A., Costiga, D. A., Koeppen, S., Korn, W. M., Brugge, S., Schmitz, D., Scheulen, M. E., King, R. H. M., Robertson, A. M., Thomas, P. K., Kerkhofs, A., Vermersch, P., Dereeper, O., Daems Monpeun, C., Parent, M., Deplanque, D., Petit, H., Campero, M., Serra, J., Ochoa, J. L., Martinez-Matos, J. A., Montero, J., Olivé, M., Rene, R., Vidaller, A., Gugenheim, M., Gouider, R., Le Guern, E., Brice, A., Agid, Y., Bouche, P., Grisold, W., Ziflo, U., Drlicek, M., Budka, H., Jellinger, K., Zielinski, C. H., Ginsberg, L., King, R. H. M., Workman, J., Platts, A. D., Thomas, P. K., Gherardi, R. K., Florea-Strat, A., Poron, F., Sabourin, J. -C., Fazio, R., Nemni, R., Franceschi, M., Lorenzetti, I., Rinaldi, L., Canal, N., Weilbach, F. X., Sennlaub, A., Jung, S., Gold, R., Toyka, K. V., Hartung, H. P., Giegerich, G., Ellie, E., Vital, A., Steck, A. J., Vital, C., Julien, J., Doneda, P., Pizzul, S., Scarpini, E., Chiodi, P., Ramacci, M. T., Livraghi, S., Maimone, D., Annunziata, P., Salvadori, C., Guazzi, G. C., Arne-Bes, M. C., Delisle, M. B., Fabre, N., Hurtevent, J. F., Bes, A., Baudoin-Martin, D., Laborde, E., Viallet, F., Creisson, C., Crespi, V., Bogliun, G., Marzorati, L., Zincone, A., D'Angelo, L., Liberani, A., Merlini, M., Rivolta, R., Creange, A., Sabourin, J. -C., Theodorou, I., Gherardi, R. K., Conti, A. M., Malosio, M. L., Baron, P. L., Scarlato, G., Chorao, R., Rosas, M. J., Leite, I., Callea, L., Donati, E., Bargnani, C., Bud, M., Verdu, E., Navarro, X., Braun, S., Einius, S., Poindron, P., Warier, J. M., Bradley, J., Bekkelund, S. I., Torbergsen, T., Mellgren, S. I., Carlomagno, S., Parlato, V., Santoro, A., Lavarone, A., Boller, F., Bonavita, V., Engelhardt, A., Lörler, H., Robeck, S., Kluglein, C., Comi, G., Avoledo, V., Locatelli, T., Leocani, L., Galardi, G., Magnani, G., Medaglini, S., Chkhikvishvili, T. S., Zangaladze, A., Bratoeva, M., Kovachev, P., Chavdarov, D., Artemis, N., Karacostas, D., Milonas, I., Arpa, J., Lopez-Pajares, R., Cruz-Matinez, A., Sarria, J., Palomo, F., Alonso, M., Rodriguez-Al-barino, A., Lacasa, T., Nos, J., Barreiro, P., Martinez, A. Cruz, Villoslada, C., Alons, M., Taghavy, A., Hamer, H., Kratzer, A., Dethy, S., Pauwels, T., Monclus, M., Luxen, A., Goldman, S., Ziegler, M., Crambes, O., Ragueneau, I., Arnaud, F., Zappia, M., Montesanti, R., Colao, R., Palmieri, A., Branca, D., Nicoletti, G., Rizzo, M., Parlato, G., Quattrone, A., Vanacore, N., Zuchegna, P., Bonifati, V., Meco, G., Scholz, J., Friedrich, H. -J., Rohl, A., Ulm, G., Vieregge, P., Savettieri, G., Rocca, W. 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M., Krauseneck P., Meyding-Lamadé, U., Krieger, D., Sartor, K., Hacke, W., Maugard-Louboutin, C., Fayet, G., Sagan, C., Martin, S., Ménégalli, D., Lajat, Y., Resche, F., Koriech, O. M., Al Moutaery, K., Yaqub, B., Jochens, R., Wolters, A., Venz, S., Cordes, M., Hecht, B. K., Chatel, M., Gaudray, P., Turc-Carel, C., Gioanni, J., Ayraud, N., Hecht, F., Rumbach, L., Racadot, E., Bataillard, M., Billot, M., Pariset, J., Wijdenes, J., Montalban, Rio J., Tintoré, M., Galan, I., Acarin, N., Rapaport, S., Huberman, M., Shechtcr, D., Karabudak, R., Kilinc, M., Boyacigil, S., Cila, A., Polo, J. M., Setien, S., Sanchez, R., Figols, J., Zubimendi, A., Nadareishvili, Z. G., Massot, R., Marés, R., Gallecho, F., Richart, C., Hernandez, M. A., Garcia, M. R., Lorenzo, J. N., Leon, C., Muros, M., Togores, J., Kutluk, K., Damlacik, G. A., Tekinsoy, B., Obuz, O., Baklan, B., Idiman, E., Genc, K., Zielasek, J., Schmidt, B., Liew, F. Y., Gulay, Z., Yulug, N., Wong, K. S., Wong, T. W., Yu, T. 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L., Constantin, C., Cassatella, M. A., Langdon, D. W., Webb, S., Gasparini, P., Zeviani, A., Kidd, D., Mammi, S., Cahalon, L., Hershkoviz, R., Lahat, N., Wallach, D., Annunziata, P., Martino, T., Maimone, D., Guazzi, G. C., Porrini, A. M., Dell'Arciprete, L., Rothwell, P. M., Stewart, R. R. C., Cull, R. E., Willmes, K., Poeck, K., Russell, D., Braekken, S. K., Brucher, R., Svennevig, J., Hermesl, M., Bruckmann, H., Biraben, A., Sliwka, U., Meyer, B., Schondube, F., Noth, J., Lavenu, I., Lammers, C., Waldecker, B., Haberbosch, W., Stam, J., Schneider, R., Gautier, J. C., Berlit, T. P., Fauser, B., Kuhne, D., Geraud, G., Danielli, A., Larrue, V., Bes, A., Timmerman, E., Bono, F., Bruni, A. C., Valalentino, P., Montesi, M. P., Talerico, G., Zappia, M., Sabatelli, M., Quattrone, A., Pareyson, D., Lorenzetti, D., Sghirlanzoni, A., Castellotti, B., Lupski, J. R., Archidiacono, N., Antonacci, R., Marzella, R., Rocchi, M., Samuel, D., Goulon-Goeau, C., Costa, P. P., Bismuth, H., Said, G., De Jongh P., Lofgren A., Timmerman V., Vance J. M., Van Broeckhoven C., Martin J. -J., Martinez, A. Cruz, Bort, S., Arpa, J., Misra, P., King, R. H. M., Badhia, K., Anderson, M., Caballo, A., Vichez, J., Gabriel, J. M., Erne, B., Miescher, G. C., Ulrich, J., Vital, A., Vital, C., Steck, A., Petry, K., Labatut, I., Hilmi, S., Ellie, E., Ferrini-Strambi, L., Zucconl, M., Marchettini, P., Palazzi, S., Oehlschlager, M., Pepinsky, R. B., Gemignani, F., Marbini, A., Pavesi, G., Di Vittorio, S., Manganelli, P., Mancia, D., Vermersh, P., Roche, J., Durocher, A. M., Dewailly, Ph., Dettmers, C., Fink, G., Lemon, R., Stephan, K., Passingham, D., Weder, B., Knorr, U., Huang, Y., Butterfield, D. A., Peris, M. L., Peiro, C., Pascual, A. Pascual-Leone, Bottini, G., Folnegovic-Smalc, V., Knezevic, S., Bokonjic, R., Ersmark, B., Torres, M. Gonzalez, Guiraud-Chaumeil, B., Haugaard, K., Jovicic, A., Chr, Lang, Levic, Z., Parra, C. Martinez, Ochoa, J. Patrignani, Titlbach, O., Wikkelso, C., Caparros-Lefevre, D., Debachy, B., Verier, A., Cantinho, G., Santos, A. I., Godinho, F., Bagunya, J., Roig, T., Ensenyat, A., Santiag, O., Trabucchi, H., De Leo, D., Koch, Ch., Zeumer, H., Matkovic, Z., Morris, P., Donaghy, M., Köhler, W., Kammer, T., Röther, J., Navon, R., Fontaine, B., Wu, Y., Capdevila, A., Guardiola, M. J., van Dijk, G. W., Notermans, N. C., Kruize, A. A., Kater, L., Bertelt, C., Hesse, S., Friedrich, H., Mauritz, K. -H., Giron, L. T., Watanabe, I. S., Ewing, D., Koepp, M., Lempert, T., Sander, B., Kauerz, U., Mehdorn, H. M., Hezel, J., Eickhoff, W., Kryst, T., Timsit, S., Gardeur, D., Reis, Mitermayer Galvao dos, Secor, E., Filho, A. Andrade, Silva, M. Cardoso, Santos, S. R. Silveira, Vasilaski, G., Reis, E. A. dos, Velupillai, P., Harn, D. A., Tigera, J. Garcia, Dreke, R. Martinez, Crespo, R. Piedra, Besses, C., Acin, P., Massons, J., Florensa, L., Oliveres, M., Sans-Sabrafen, J., Wicklein, E. M., Pleiffer, G., Kunre, K., Dieterich, M., Brandt, Th., Guarino, M., Stracciari, A., Pazzaglia, P., D'Alessandro, R., Santilli, I., Donato, M., The European Velnacrine Study Group, The Dutch Guillain-Barré study group, The COP-1 Multicenter Clinical and Research Group Study, and European Study Group
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- 1994
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183. Primer extension assay for prion protein genotype determination in sheep
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Vaccari, G, Conte, M, Morelli, L, Di Guardo, G, Petraroli, R, and Agrimi, U
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- 2004
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184. Superallergens: a novel mechanism of IgE-mediated activation of human basophils and mast cells
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Marone, G., Rossi, F. W., Bova, M., Detoraki, A., Liccardo, B., and Petraroli, A.
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- 2004
185. Reproduction, larval development and post-larval growth ofNaineris laevigata (Polychaeta, Orbiniidae) in the Mediterranean Sea
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Giangrande, A. and Petraroli, A.
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- 1991
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186. Phenotypical and functional heterogeneity of human lung macrophages: 114
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Granata, F., Balestrieri, B., Petraroli, A., Giannatasio, G., Morabito, P., and Triggiani, M.
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- 2003
187. Late Breaking Poster Discussion LB PDS
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Maria Alessio, Gianni Marone, Marco Cicardi, Maria Domenica Guarino, Maria Bova, Raffaella De Falco, Livia Savarese, Andrea Zanichelli, Angelica Petraroli, Massimo Triggiani, Paolo Valerio, Eugenio Zito, Maria Francesca Freda, Mauro Cancian, and Roberto Perricone
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Health psychology ,business.industry ,Immunology ,Stress (linguistics) ,Hereditary angioedema ,Immunology and Allergy ,Medicine ,business ,medicine.disease ,Clinical psychology - Published
- 2016
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188. Role of human FcϵRI+ cells in HIV-1 infection
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Marone, Gianni, Florio, Giovanni, Petraroli, Angelica, Triggiani, Massimo, and de Paulis, Amato
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- 2001
189. An investigation of nanoparticles addition on solidification kinetics and microstructure development of tin–lead solder
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Lin, D.C., Liu, S., Guo, T.M., Wang, G.-X., Srivatsan, T.S., and Petraroli, M.
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- 2003
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190. Dysregulation of the IgE/FcεRI network in HIV-1 infection
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Marone, Gianni, Florio, Giovanni, Petraroli, Angelica, and de Paulis, Amato
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- 2001
191. The tensile response and fracture behavior of 2009 aluminum alloy metal matrix composite
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Srivatsan, T.S, Al-Hajri, Meslet, Smith, C, and Petraroli, M
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- 2003
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192. Mortality trend from sporadic Creutzfeldt-Jakob disease (CJD) in Italy, 1993–2000
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Puopolo, Maria, Ladogana, Anna, Almonti, Susanna, Daude, Nathalie, Bevivino, Simona, Petraroli, Rosella, Poleggi, Anna, Quanguo, Liu, and Pocchiari, Maurizio
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- 2003
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193. The immunoglobulin superantigen-binding site of HIV-1 gp120 activates human basophils
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Florio, Giovanni, Petraroli, Angelica, Patella, Vincenzo, Triggiani, Massimo, and Marone, Gianni
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- 2000
194. Comparative effectiveness of breathing exercises in patients with chronic obstructive pulmonary disease
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Annalisa Petraroli, Lucrezia Moggio, Francesco Lavano, Cinzia Marinaro, Nicola Marotta, Marianna Barletta, Davide Pepe, Andrea Demeco, Ilaria Pino, and Antonio Ammendolia
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Adult ,medicine.medical_specialty ,MEDLINE ,Pulmonary disease ,Diaphragmatic breathing ,Cochrane Library ,Breathing Exercises ,law.invention ,Pulmonary Disease, Chronic Obstructive ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,law ,medicine ,Humans ,In patient ,030212 general & internal medicine ,COPD ,business.industry ,Yoga ,medicine.disease ,humanities ,Meditation ,Complementary and alternative medicine ,Breathing exercises ,Quality of Life ,Physical therapy ,business ,030217 neurology & neurosurgery - Abstract
Background and purpose This study aims to determine the best choice of breathing exercises (BE) for patients with chronic obstructive pulmonary disease (COPD) via a network meta-analysis. Methods We searched randomized controlled trials (RCTs) of adults with COPD investigating any BEs in MEDLINE, Embase, Cochrane Library, and ClinicalTrials.gov databases. The effects of comparative treatment on the St. George Respiratory Questionnaire as the outcome were analysed and ranked according to a surface under the cumulative classification curve (SUCRA) analysis. Results The network meta-analysis included six RCTs involving 280 patients with four intervention groups, comprising control, diaphragmatic breathing training (DBT), yoga, and singing course. Performing SUCRA, we reported that yoga is 75% likely to be the best treatment available as DBT with 66%, instead of 35% for singing and 21% for control. Conclusion DBT and yoga seem to be the best choices for breathing exercises in people with COPD.
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- 2020
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195. Gender in Japan: The Unseen Aspect of Natural Disaster Risks.
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Petraroli, Irene and Jane Singer
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WOMEN'S empowerment , *JAPANESE women , *GENDER studies , *NATURAL disasters , *EMERGENCY management - Abstract
During a natural disaster, the role of gender is a sensitive but unexplored topic. Research is needed not only to improve existing policies in disaster risk reduction, but also to inspire new ways to strengthen disaster resilience through gender equality. This project based on disaster preparedness in Japan not only adds to the conference focus on women empowerment in a specific context, but also gives the opportunity to discuss gender beyond the dominant Western paradigms. The focus on disaster prevention is not casual. The scarcity of information and fora of discussion on gender is one of the reasons for Japan's low level of gender equality. However, since disaster prevention is a universal concern, disaster education is the ideal opportunity to educate the public about gender awareness. In the current Japanese disaster education, gender is under- or mis-represented and the image of disaster differs from a realistic gendered experience. These problems led to the question "what is the public perception of gender-based disaster risk?", and "does gender impact the perceptions of gender-based risks?". To answer these questions, a survey based on behavioural-cognitive theory was designed to assess the public interest and the available information on gender during a disaster. Then, the responses were expanded and contextualised through observations, interviews and workshops. The results showed high interest for a gender perspective on disaster, but also significant differences between male and female respondents. The study also suggested a "cultural" understanding of gender in disaster based on the gendered stereotypes and expectations relied upon in case of disaster. [ABSTRACT FROM AUTHOR]
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- 2020
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196. Altered Metabolism of Phospholipases, Diacylglycerols, Endocannabinoids, and
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Anne Lise, Ferrara, Fabiana, Piscitelli, Angelica, Petraroli, Roberta, Parente, Maria Rosaria, Galdiero, Gilda, Varricchi, Giancarlo, Marone, Massimo, Triggiani, Vincenzo, Di Marzo, and Stefania, Loffredo
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Adult ,Male ,Polyunsaturated Alkamides ,Arachidonic Acids ,Middle Aged ,Diglycerides ,Phospholipases A2 ,Ethanolamines ,Type C Phospholipases ,Humans ,lipids (amino acids, peptides, and proteins) ,Female ,Tryptases ,Biomarkers ,Mastocytosis ,Aged ,Endocannabinoids ,Research Article - Abstract
Background Mastocytosis is a condition characterized by the expansion and accumulation of mast cells (MCs) in various organs. The symptoms are related to the increased release of MC-derived mediators that exert local and distant effects. MCs are a source and target of phospholipase enzymes (PLs), which catalyze the cleavage of membrane phospholipids releasing lipid mediators (e.g., diacylglycerols (DAGs) and the endocannabinoid (EC) 2-arachidonoylglycerol (2-AG)). To date, there are no data on the role of these lipid mediators in mastocytosis. Here, we analyzed plasma levels of PLA2, PLC, DAG, ECs, and EC-related N-acylethanolamines in patients with mastocytosis. Methods In 23 patients with mastocytosis and 23 healthy individuals, we measured plasma PLA2 and PLC activities, DAG, 2-AG, anandamide (AEA), palmitoylethanolamide (PEA), and oleoylethanolamide (OEA). Results Plasma PLA2 and PLC activities were increased in mastocytosis patients compared to controls. Concentrations of DAG (18:1 20:4 and 18:0 20:4), two second messengers produced by PLC, were higher in mastocytosis compared to controls, whereas the concentrations of their metabolite, 2-AG, were not altered. AEA was decreased in mastocytosis patients compared to controls; by contrast, AEA congener, PEA, was increased. PLA2 and PLC activities were increased only in patients with mediator-related symptoms. Moreover, PLC activity was positively correlated with disease severity and tryptase concentrations. By contrast, AEA was negatively correlated with tryptase concentrations. Conclusions PLs and some lipid mediators are altered in patients with mastocytosis. Our results may pave the way for investigating the functions of these mediators in the pathophysiology of mastocytosis and provide new potential biomarkers and therapeutic targets.
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- 2018
197. Biotelemetria: desenvolvimento de um negócio para saúde de idosos
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Petraroli, Alessandra Gallo, Escolas::EAESP, Alberto, Fernando Lopes, Iizuka, Edson Sadao, and Aidar, Marcelo Marinho
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Telemonitoring ,Telemonitoramento ,Telemedicina ,Telemedicine ,Evidence-based health ,Idosos ,Saúde baseada em evidências ,Administração de empresas ,Informática na medicina ,Idosos - Cuidados médicos ,Biotelemetria ,Medicina - Processamento de dados ,Biotelemetry ,Aged ,Serviços de saúde - Inovações tecnológicas - Abstract
Este trabalho realizou o desenvolvimento de um negócio baseado em mHealth, biotelemetria e algoritmos de análise (analytics). A transmissão de dados é feita por Internet of Things (IoT) – em português internet das coisas, uma rede onde todos os objetos se comunicam e interagem de forma autônoma via internet. O objetivo do uso destas tecnologias é viabilizar o telemonitoramento de idosos. Telemonitoramento é uma subárea da telemedicina, que permite o monitoramento e gerenciamento de dispositivos e sensores médicos via software para aumentar a eficiência dos processos, neste caso, processos de monitoramento a idosos crônicos. Há um bom potencial de inovação que demanda pesquisa científica e tecnológica. A startup Virtual Monitor possui equipe com competências para executar este projeto específico. Realizou-se uma análise de potencial de mercado, nos critérios de atratividade e competitividade, e observou-se que a inovação levará ao desenvolvimento de um produto economicamente sustentável e trará ganhos comerciais. Este plano é um ponto de partida que conclui que para simplificar e escalar o acompanhamento de idosos faz-se necessária uma solução que envolva cuidado centrado nas pessoas, tecnologia adaptada às pessoas e a inclusão da terapêutica digital para idosos. Este cenário se mostrou atrativo do ponto de vista de investimento com potencial de crescimento de mercado de saúde suplementar. This work carried out the development of a business based on mHealth, biotelemetria and analytical algorithms. The transmission of data is done by Internet of Things (IoT) - in Portuguese internet of things, a network where all objects that communicate and interact in an autonomous way via internet. The objective of the use of these technologies is to enable telemonitoring of the elderly. Telemonitoring is a subarea of telemedicine, which allows the monitoring and management of medical devices and sensors via software to increase the efficiency of the processes, in this case, monitoring processes for the chronic elderly. There is good potential for innovation that demands scientific and technological research. Startup Virtual Monitor has team with competencies to execute this specific project. An analysis of market potential was made, in the criteria of attractiveness and competitiveness, and it was observed that innovation will lead to the development of an economically sustainable product and will bring commercial gains. This plan is a starting point and concludes that to simplify the follow-up of the elderly, a solution is necessary that involves person-centered care, technology adapted to the people and the inclusion of digital therapy for the elderly. In this scenario, it was attractive from the investment point of view with the growth potential of the supplementary health market.
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- 2018
198. Secreted Phospholipases A
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Stefania, Loffredo, Anne Lise, Ferrara, Maria, Bova, Francesco, Borriello, Chiara, Suffritti, Nóra, Veszeli, Angelica, Petraroli, Maria Rosaria, Galdiero, Gilda, Varricchi, Francescopaolo, Granata, Andrea, Zanichelli, Henriette, Farkas, Marco, Cicardi, Gérard, Lambeau, and Gianni, Marone
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angiogenesis ,vascular endothelial growth factor ,Immunology ,phospholipase A2 ,C1 inhibitor deficiency ,bacterial infections and mycoses ,vascular permeability ,hereditary angioedema ,angiopoietins ,Original Research - Abstract
Background Hereditary angioedema (HAE) caused by deficiency (type I) or dysfunction (type II) of the C1 inhibitor protein (C1-INH-HAE) is a disabling, potentially fatal condition characterized by recurrent episodes of swelling. We have recently found that patients with C1-INH-HAE have increased plasma levels of vascular endothelial growth factors and angiopoietins (Angs), which have been associated with vascular permeability in several diseases. Among these and other factors, blood endothelial cells and vascular permeability can be modulated by extracellular or secreted phospholipases A2 (sPLA2s). Objective We sought to investigate the enzymatic activity and biological functions of sPLA2 in patients with C1-INH-HAE. Methods sPLA2s enzymatic activity was evaluated in the plasma from 109 adult patients with C1-INH-HAE and 68 healthy donors in symptom-free period and attacks. Plasma level of group IIA sPLA2 (hGIIA) protein was measured in selected samples. The effect of C1-INH-HAE plasma on endothelial permeability was examined in vitro using a vascular permeability assay. The role of hGIIA was determined using highly specific sPLA2 indole inhibitors. The effect of recombinant hGIIA on C1-INH activity was examined in vitro by functional assay. Results Plasma sPLA2 activity and hGIIA levels are increased in symptom-free C1-INH-HAE patients compared with controls. sPLA2 activity negatively correlates with C1-INH protein level and function. C1-INH-HAE plasma increases endothelial permeability in vitro, and this effect is partially reverted by a specific hGIIA enzymatic inhibitor. Finally, recombinant hGIIA inhibits C1-INH activity in vitro. Conclusion sPLA2 enzymatic activity (likely attributable to hGIIA), which is increased in C1-INH-HAE patients, can promote vascular permeability and impairs C1-INH activity. Our results may pave the way for investigating the functions of sPLA2s (in particular, hGIIA) in the pathophysiology of C1-INH-HAE and may inform the development of new therapeutic targets.
- Published
- 2018
199. Additional file 1: of Simultaneous detection of lung fusions using a multiplex RT-PCR next generation sequencing-based approach: a multi-institutional research study
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Vaughn, Cecily, Costa, José, Feilotter, Harriet, Petraroli, Rosella, Varun Bagai, Rachiglio, Anna, Marino, Federica, Tops, Bastiaan, Kurth, Henriette, Sakai, Kazuko, Mafficini, Andrea, Bastien, Roy, Reiman, Anne, Corre, Delphine Le, Boag, Alexander, Crocker, Susan, Bihl, Michel, Hirschmann, Astrid, Scarpa, Aldo, Machado, José, Blons, Hélène, Sheils, Orla, Bramlett, Kelli, Ligtenberg, Marjolijn, Cree, Ian, Normanno, Nicola, Nishio, Kazuto, and Laurent-Puig, Pierre
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Table S1. RT-PCR Targets within the Ion AmpliSeq™ Lung Fusion Research Panel. A list of all targets in the multiplex PCR studied – including targeted fusions (genes and exons), expression control genes, and 3′and 5′regions. Table S2. ALK Clinical Samples. Table depicting details on all ALK clinical research samples analyzed in the study. Table S3. ROS1 and RET clinical samples. Table depicting details on all ROS1 and RET clinical research samples analyzed in the study. (DOCX 57 kb)
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- 2018
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200. Additional file 1: of Emotional processes and stress in children affected by hereditary angioedema with C1-inhibitor deficiency: a multicenter, prospective study
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Savarese, Livia, Bova, Maria, Falco, Raffaella De, Guarino, Maria, Picione, Raffaele De Luca, Petraroli, Angelica, Senter, Riccardo, Traverso, Claudia, Zabotto, Matteo, Zanichelli, Andrea, Zito, Eugenio, Alessio, Maria, Cancian, Mauro, Cicardi, Marco, Franzese, Adriana, Perricone, Roberto, Marone, Gianni, Valerio, Paolo, and Freda, Maria
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Table S1. Binary Logistic Regression analysis: Coddington Life Event Scale (CLES) versus Total Severity Score and Alexithymia Questionnaire for Children (AQC). (DOCX 20 kb)
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- 2018
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