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167. HIGHLY FUNCTIONAL DUODENAL STENT WITH CONTROLLED RADICAL OXYGEN SPECIES RELEASE FOR THE TREATMENT OF METABOLIC DISEASES

Author

Park, Ji Hoon, primary, Kim, So Jeong, additional, Jo, Jung Hyun, additional, Lee, Hee Seung, additional, Song, Jung Min, additional, Park, Jae Myung, additional, Park, Jeong Youp, additional, Bang, Seungmin, additional, Park, Seung Woo, additional, Na, Kun, additional, Kang, Sung-Gwon, additional, Jung, Hwoon-Yong, additional, Song, Si Young, additional, and Chung, Moon Jae, additional

Published
2022
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168. Clinical profile and outcome of recurrent infective endocarditis

Author

Citro, Rodolfo, primary, Chan, Kwan-Leung, additional, Miglioranza, Marcelo Haertel, additional, Laroche, Cécile, additional, Benvenga, Rossella Maria, additional, Furnaz, Shumaila, additional, Magne, Julien, additional, Olmos, Carmen, additional, Paelinck, Bernard P., additional, Pasquet, Agnès, additional, Piper, Cornelia, additional, Salsano, Antonio, additional, Savouré, Arnaud, additional, Park, Seung Woo, additional, Szymański, Piotr, additional, Tattevin, Pierre, additional, Vallejo Camazon, Nuria, additional, Lancellotti, Patrizio, additional, and Habib, Gilbert, additional

Published
2022
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170. Normal Values of Left Ventricular Size and Function on Three-Dimensional Echocardiography: Results of the World Alliance Societies of Echocardiography Study

Author

Addetia, Karima, primary, Miyoshi, Tatsuya, additional, Amuthan, Vivekanandan, additional, Citro, Rodolfo, additional, Daimon, Masao, additional, Gutierrez Fajardo, Pedro, additional, Kasliwal, Ravi R., additional, Kirkpatrick, James N., additional, Monaghan, Mark J., additional, Muraru, Denisa, additional, Ogunyankin, Kofo O., additional, Park, Seung Woo, additional, Ronderos, Ricardo E., additional, Sadeghpour, Anita, additional, Scalia, Gregory M., additional, Takeuchi, Masaaki, additional, Tsang, Wendy, additional, Tucay, Edwin S., additional, Tude Rodrigues, Ana Clara, additional, Zhang, Yun, additional, Hitschrich, Niklas, additional, Blankenhagen, Michael, additional, Degel, Markus, additional, Schreckenberg, Marcus, additional, Mor-Avi, Victor, additional, Asch, Federico M., additional, Lang, Roberto M., additional, Prado, Aldo D., additional, Filipini, Eduardo, additional, Kwon, Agatha, additional, Hoschke-Edwards, Samantha, additional, Afonso, Tania Regina, additional, Thampinathan, Babitha, additional, Sooriyakanthan, Maala, additional, Zhu, Tiangang, additional, Wang, Zhilong, additional, Wang, Yingbin, additional, Yin, Lixue, additional, Li, Shuang, additional, Alagesan, R., additional, Balasubramanian, S., additional, Ananth, R.V.A., additional, Bansal, Manish, additional, Badano, Luigi, additional, Bossone, Eduardo, additional, Di Vece, Davide, additional, Bellino, Michele, additional, Nakao, Tomoko, additional, Kawata, Takayuki, additional, Hirokawa, Megumi, additional, Sawada, Naoko, additional, Nabeshima, Yousuke, additional, Yun, Hye Rim, additional, and Hwang, Ji-Won, additional

Published
2022
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171. 557: AN INTEGRATIVE ANALYSIS OF PANCREATIC CANCER CELLS AND CANCER-ASSOCIATED FIBROBLASTS USING SINGLE CELL TRANSCRIPTOMIC ANALYSIS

Author

Leem, Galam, primary, Kim, Seongryong, additional, Hwang, Ho Kyoung, additional, Jo, Jung Hyun, additional, Lee, Hee Seung, additional, Chung, Moon Jae, additional, Park, Jeong Youp, additional, Park, Seung Woo, additional, Song, Si Young, additional, Shin, Eui-Cheol, additional, Kang, Chang Moo, additional, Park, Jong-Eun, additional, and Bang, Seungmin, additional

Published
2022
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173. Clinical profile and outcome of recurrent infective endocarditis

Author

UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - (SLuc) Département cardiovasculaire, Citro, Rodolfo, Chan, Kwan-Leung, Miglioranza, Marcelo Haertel, Laroche, Cécile, Benvenga, Rossella Maria, Furnaz, Shumaila, Magne, Julien, Olmos, Carmen, Paelinck, Bernard P., Pasquet, Agnès, Piper, Cornelia, Salsano, Antonio, Savouré, Arnaud, Park, Seung Woo, Szymański, Piotr, Tattevin, Pierre, Vallejo Camazon, Nuria, Lancellotti, Patrizio, Habib, Gilbert, UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - (SLuc) Département cardiovasculaire, Citro, Rodolfo, Chan, Kwan-Leung, Miglioranza, Marcelo Haertel, Laroche, Cécile, Benvenga, Rossella Maria, Furnaz, Shumaila, Magne, Julien, Olmos, Carmen, Paelinck, Bernard P., Pasquet, Agnès, Piper, Cornelia, Salsano, Antonio, Savouré, Arnaud, Park, Seung Woo, Szymański, Piotr, Tattevin, Pierre, Vallejo Camazon, Nuria, Lancellotti, Patrizio, and Habib, Gilbert

Abstract

Aims Purpose of this study is to compare the clinical course and outcome of patients with recurrent versus first-episode infective endocarditis (IE). Methods Patients with recurrent and first-episode IE enrolled in the EUROpean ENDOcarditis (EURO-ENDO) registry including 156 centres were identified and compared using propensity score matching. Recurrent IE was classified as relapse when IE occurred ≤6 months after a previous episode or reinfection when IE occurred >6 months after the prior episode. Results 3106 patients were enrolled: 2839 (91.4%) patients with first-episode IE (mean age 59.4 (±18.1); 68.3% male) and 267 (8.6%) patients with recurrent IE (mean age 58.1 (±17.7); 74.9% male). Among patients with recurrent IE, 13.2% were intravenous drug users (IVDUs), 66.4% had a repaired or replaced valve with the tricuspid valve being more frequently involved compared with patients with first-episode IE (20.3% vs 14.1%; p=0.012). In patients with a first episode of IE, the aortic valve was more frequently involved (45.6% vs 39.5%; p=0.061). Recurrent relapse and reinfection were 20.6% and 79.4%, respectively. Staphylococcus aureus was the microorganism most frequently observed in both groups (p=0.207). There were no differences in in-hospital and post-hospitalisation mortality between recurrent and first-episode IE. In patients with recurrent IE, in-hospital mortality was higher in IVDU patients. Independent predictors of poorer in-hospital and 1-year outcome, including the occurrence of cardiogenic and septic shock, valvular disease severity and failure to undertake surgery when indicated, were similar for recurrent and first-episode IE. Conclusions In-hospital and 1-year mortality was similar in patients with recurrent and first-episode IE who shared similar predictors of poor outcome.

Published
2022

174. Normal Values of Aortic Root Size According to Age, Sex, and Race: Results of the World Alliance of Societies of Echocardiography Study

Author

Patel, H, Miyoshi, T, Addetia, K, Citro, R, Daimon, M, Gutierrez Fajardo, P, Kasliwal, R, Kirkpatrick, J, Monaghan, M, Muraru, D, Ogunyankin, K, Park, S, Ronderos, R, Sadeghpour, A, Scalia, G, Takeuchi, M, Tsang, W, Tucay, E, Tude Rodrigues, A, Amuthan, V, Zhang, Y, Schreckenberg, M, Blankenhagen, M, Degel, M, Hitschrich, N, Mor-Avi, V, Asch, F, Lang, R, Patel, Hena N, Miyoshi, Tatsuya, Addetia, Karima, Citro, Rodolfo, Daimon, Masao, Gutierrez Fajardo, Pedro, Kasliwal, Ravi R, Kirkpatrick, James N, Monaghan, Mark J, Muraru, Denisa, Ogunyankin, Kofo O, Park, Seung Woo, Ronderos, Ricardo E, Sadeghpour, Anita, Scalia, Gregory M, Takeuchi, Masaaki, Tsang, Wendy, Tucay, Edwin S, Tude Rodrigues, Ana Clara, Amuthan, Vivekanandan, Zhang, Yun, Schreckenberg, Marcus, Blankenhagen, Michael, Degel, Markus, Hitschrich, Niklas, Mor-Avi, Victor, Asch, Federico M, Lang, Roberto M, Patel, H, Miyoshi, T, Addetia, K, Citro, R, Daimon, M, Gutierrez Fajardo, P, Kasliwal, R, Kirkpatrick, J, Monaghan, M, Muraru, D, Ogunyankin, K, Park, S, Ronderos, R, Sadeghpour, A, Scalia, G, Takeuchi, M, Tsang, W, Tucay, E, Tude Rodrigues, A, Amuthan, V, Zhang, Y, Schreckenberg, M, Blankenhagen, M, Degel, M, Hitschrich, N, Mor-Avi, V, Asch, F, Lang, R, Patel, Hena N, Miyoshi, Tatsuya, Addetia, Karima, Citro, Rodolfo, Daimon, Masao, Gutierrez Fajardo, Pedro, Kasliwal, Ravi R, Kirkpatrick, James N, Monaghan, Mark J, Muraru, Denisa, Ogunyankin, Kofo O, Park, Seung Woo, Ronderos, Ricardo E, Sadeghpour, Anita, Scalia, Gregory M, Takeuchi, Masaaki, Tsang, Wendy, Tucay, Edwin S, Tude Rodrigues, Ana Clara, Amuthan, Vivekanandan, Zhang, Yun, Schreckenberg, Marcus, Blankenhagen, Michael, Degel, Markus, Hitschrich, Niklas, Mor-Avi, Victor, Asch, Federico M, and Lang, Roberto M

Abstract

Background: Accurate measurements of the aortic annulus and root are important for guiding therapeutic decisions regarding the need for aortic surgery. Current echocardiographic guidelines for identification of aortic root dilatation are limited because current normative values were derived predominantly from white individuals in narrow age ranges, and based partially on M-mode measurements. Using data from the World Alliance Societies of Echocardiography study, the authors sought to establish normal ranges of aortic dimensions across sexes, races, and a wide range of ages. Methods: Adult individuals free of heart, lung, and kidney disease were prospectively enrolled from 15 countries, with even distributions among sexes and age groups: young (18–40 years), middle aged (41–65 years) and old (>65 years). Transthoracic two-dimensional echocardiograms of 1,585 subjects (mean age, 47 ± 17 years; 50.4% men; mean body surface area [BSA], 1.77 ± 0.22 m2) were analyzed in a core laboratory following American Society of Echocardiography guidelines. Measurements, indexed separately by BSA and by height, included the aortic annulus, sinuses of Valsalva, and sinotubular junction. Differences among age, sex, and racial groups were evaluated using unpaired two-tailed Student's t tests. Results: All aortic root dimensions were larger in men compared with women. After indexing to BSA, all measured dimensions were significantly larger in women, whereas men continued to show larger dimensions after indexing to height. Of note, the upper limits of normal for all aortic dimensions were lower across all age groups, compared with the guidelines. Aortic dimensions were larger in older age groups in both sexes, a trend that persisted regardless of BSA or height adjustment. Last, differences in aortic dimensions were also observed according to race: Asians had the smallest nonindexed aortic dimensions at all levels. Conclusions: There are significant differences in aortic dimensions acco

Published
2022

179. A randomized, multicenter, phase III study of gemcitabine combined with capecitabine versus gemcitabine alone as first-line chemotherapy for advanced pancreatic cancer in South Korea

Author

Lee, Hee Seung, Chung, Moon Jae, Park, Jeong Youp, Bang, Seungmin, Park, Seung Woo, Kim, Ho Gak, Noh, Myung Hwan, Lee, Sang Hyub, Kim, Yong-Tae, Kim, Hyo Jung, Kim, Chang Duck, Lee, Dong Ki, Cho, Kwang Bum, Cho, Chang Min, Moon, Jong Ho, Kim, Dong Uk, Kang, Dae Hwan, Cheon, Young Koog, Choi, Ho Soon, Kim, Tae Hyeon, Kim, Jae Kwang, Moon, Jieun, Shin, Hye Jung, and Song, Si Young

Published
2017
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184. A prospective, open-label, multicenter study of the clinical efficacy of extended-release hydromorphone in treating cancer pain inadequately controlled by other analgesics

Author

Han, Hye-Suk, Lee, Ki Hyeong, Lee, Kyung Hee, Ryu, Jeong Seon, Kim, Young Chul, Park, Seung Woo, Oh, Ho-Suk, Park, Kyung Tae, Kwon, Jung Hye, Lee, Pyung Bok, Lee, Won Sik, Kim, Yang Soo, Ahn, Joong Bae, Jeon, Seong Woo, Lee, Sung Yong, Seol, Young Mi, Kang, Jung Hun, Yuh, Young Jin, Oh, So Yeon, Kim, Suk Ran, and Ahn, Jin Seok

Published
2014
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185. Normative values of the aortic valve area and Doppler measurements using two-dimensional transthoracic echocardiography: results from the Multicentre World Alliance of Societies of Echocardiography Study.

Author

Cotella, Juan I, Miyoshi, Tatsuya, Mor-Avi, Victor, Addetia, Karima, Schreckenberg, Marcus, Sun, Deyu, Slivnick, Jeremy A, Blankenhagen, Michael, Hitschrich, Niklas, Amuthan, Vivekanandan, Citro, Rodolfo, Daimon, Masao, Gutiérrez-Fajardo, Pedro, Kasliwal, Ravi, Kirkpatrick, James N, Monaghan, Mark J, Muraru, Denisa, Ogunyankin, Kofo O, Park, Seung Woo, and Rodrigues, Ana Clara Tude

Subjects
ECHOCARDIOGRAPHY, RESEARCH evaluation, AORTIC stenosis, POPULATION geography, RACE, DOPPLER echocardiography, SEX distribution, DESCRIPTIVE statistics, AORTIC valve
Abstract

Aims Aortic valve area (AVA) used for echocardiographic assessment of aortic stenosis (AS) has been traditionally interpreted independently of sex, age and race. As differences in normal values might impact clinical decision-making, we aimed to establish sex-, age- and race-specific normative values for AVA and Doppler parameters using data from the World Alliance Societies of Echocardiography (WASE) Study. Methods and results Two-dimensional transthoracic echocardiographic studies were obtained from 1903 healthy adult subjects (48% women). Measurements of the left ventricular outflow tract (LVOT) diameter and Doppler parameters, including AV and LVOT velocity time integrals (VTIs), AV mean pressure gradient, peak velocity, were obtained according to ASE/EACVI guidelines. AVA was calculated using the continuity equation. Compared with men, women had smaller LVOT diameters and AVA values, and higher AV peak velocities and mean gradients (all P < 0.05). LVOT and AV VTI were significantly higher in women (P < 0.05), and both parameters increased with age in both sexes. AVA differences persisted after indexing to body surface area. According to the current diagnostic criteria, 13.5% of women would have been considered to have mild AS and 1.4% moderate AS. LVOT diameter and AVA were lower in older subjects, both men and women, and were lower in Asians, compared with whites and blacks. Conclusion WASE data provide clinically relevant information about significant differences in normal AVA and Doppler parameters according to sex, age, and race. The implementation of this information into clinical practice should involve development of specific normative values for each ethnic group using standardized methodology. [ABSTRACT FROM AUTHOR]

Published
2023
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191. Response to Neoadjuvant Therapy and Prognosis in Patients with Resectable Pancreatic Cancer: A Propensity Score Matching Analysis

Author

Yoon, Min Sung, primary, Lee, Hee Seung, additional, Kang, Chang Moo, additional, Lee, Woo Jung, additional, Keum, Jiyoung, additional, Sung, Min Je, additional, Kim, Seung-seob, additional, Park, Mi-Suk, additional, Jo, Jung Hyun, additional, Chung, Moon Jae, additional, Park, Jeong Youp, additional, Park, Seung Woo, additional, Song, Si Young, additional, Hwang, Ho Kyoung, additional, and Bang, Seungmin, additional

Published
2022
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