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152. Contributors

Author

Kjersti Aagaard, Fredrick M. Abrahamian, Ban Mishu Allos, David R. Andes, Fred Y. Aoki, Michael A. Apicella, Kevin L. Ard, Cesar A. Arias, David M. Aronoff, Michael H. Augenbraun, Francisco Averhoff, Dimitri T. Azar, Larry M. Baddour, Lindsey R. Baden, Carol J. Baker, Ronald C. Ballard, Gerard R. Barber, Scott D. Barnes, Dan H. Barouch, Alan D. Barrett, Miriam Baron Barshak, Sridhar V. Basavaraju, Byron E. Batteiger, Stephen G. Baum, Arnold S. Bayer, J. David Beckham, Susan E. Beekmann, Beth P. Bell, John E. Bennett, Dennis A. Bente, Elie F. Berbari, Jonathan Berman, Joseph S. Bertino, Adarsh Bhimraj, Holly H. Birdsall, Alan L. Bisno, Brian G. Blackburn, Lucas S. Blanton, Martin J. Blaser, Thomas P. Bleck, Nicole M.A. Blijlevens, David A. Bobak, William Bonnez, John C. Boothroyd, Luciana L. Borio, Patrick J. Bosque, John Bower, Robert W. Bradsher, Itzhak Brook, Kevin E. Brown, Patricia D. Brown, Barbara A. Brown-Elliott, Roberta L. Bruhn, Amy E. Bryant, Eileen M. Burd, Jane C. Burns, Larry M. Bush, Stephen B. Calderwood, Luz Elena Cano, Charles C.J. Carpenter, Mary T. Caserta, Elio Castagnola, Richard E. Chaisson, Henry F. Chambers, Stephen J. Chapman, James D. Chappell, Lea Ann Chen, Sharon C-A Chen, Anthony W. Chow, Rebecca A. Clark, Jeffrey I. Cohen, Myron S. Cohen, Ronit Cohen-Poradosu, Susan E. Cohn, Mark Connors, Lawrence Corey, Mackenzie L. Cottrell, Timothy L. Cover, Heather L. Cox, William A. Craig, Kent B. Crossley, Clyde S. Crumpacker, James W. Curran, Bart J. Currie, Erika D'Agata, Inger K. Damon, Rabih O. Darouiche, Roberta L. DeBiasi, George S. Deepe, Carlos del Rio, Andrew S. Delemos, Frank R. DeLeo, Gregory P. DeMuri, Peter Densen, Terence S. Dermody, Robin Dewar, James H. Diaz, Carl W. Dieffenbach, Jules L. Dienstag, Yohei Doi, Raphael Dolin, J. Peter Donnelly, Michael S. Donnenberg, Gerald R. Donowitz, Philip R. Dormitzer, James M. Drake, J. Stephen Dumler, J. Stephen Dummer, Herbert L. DuPont, David T. Durack, Marlene L. Durand, Paul H. Edelstein, Michael B. Edmond, John E. Edwards, Morven S. Edwards, George M. Eliopoulos, Richard T. Ellison, Timothy P. Endy, N. Cary Engleberg, Hakan Erdem, Joel D. Ernst, Peter B. Ernst, Rick M. Fairhurst, Jessica K. Fairley, Stanley Falkow, Ann R. Falsey, Anthony S. Fauci, Thomas Fekete, Paul D. Fey, Steven M. Fine, Daniel W. Fitzgerald, Anthony R. Flores, Derek Forster, Vance G. Fowler, David O. Freedman, Arthur M. Friedlander, John N. Galgiani, John I. Gallin, Robert C. Gallo, Tejal N. Gandhi, Wendy S. Garrett, Charlotte A. Gaydos, Thomas W. Geisbert, Jeffrey A. Gelfand, Steven P. Gelone, Dale N. Gerding, Anne A. Gershon, Janet R. Gilsdorf, Ellie J.C. Goldstein, Fred M. Gordin, Paul S. Graman, M. Lindsay Grayson, Jeffrey Bruce Greene, Patricia M. Griffin, David E. Griffith, Richard L. Guerrant, H. Cem Gul, David A. Haake, David W. Haas, Charles Haines, Caroline Breese Hall, Joelle Hallak, Scott A. Halperin, Margaret R. Hammerschlag, Rashidul Haque, Jason B. Harris, Claudia Hawkins, Roderick J. Hay, Craig W. Hedberg, David K. Henderson, Donald A. Henderson, Kevin P. High, Adrian V.S. Hill, David R. Hill, Alan R. Hinman, Martin S. Hirsch, Aimee Hodowanec, Tobias M. Hohl, Steven M. Holland, Robert S. Holzman, Edward W. Hook, David C. Hooper, Thomas M. Hooton, Harold W. Horowitz, C. Robert Horsburgh, James M. Horton, Duane R. Hospenthal, Kevin Hsueh, James M. Hughes, Noreen A. Hynes, Nicole M. Iovine, Jonathan R. Iredell, Michael G. Ison, J. Michael Janda, Edward N. Janoff, Eric C. Johannsen, Angela D.M. Kashuba, Dennis L. Kasper, Donald Kaye, Keith S. Kaye, Kenneth M. Kaye, James W. Kazura, Jay S. Keystone, Rima Khabbaz, David A. Khan, Yury Khudyakov, Rose Kim, Charles H. King, Louis V. Kirchhoff, Jerome O. Klein, Michael Klompas, Bettina M. Knoll, Kirk U. Knowlton, Jane E. Koehler, Stephan A. Kohlhoff, Eija Könönen, Dimitrios P. Kontoyiannis, Igor J. Koralnik, Poonum S. Korpe, Anita A. Koshy, Joseph A. Kovacs, Phyllis Kozarsky, John Krieger, Andrew T. Kroger, Matthew J. Kuehnert, Nalin M. Kumar, Merin Elizabeth Kuruvilla, Regina C. LaRocque, James E. Leggett, Helena Legido-Quigley, Paul N. Levett, Donald P. Levine, Matthew E. Levison, Alexandra Levitt, Russell E. Lewis, W. Conrad Liles, Aldo A.M. Lima, Ajit P. Limaye, W. Ian Lipkin, Nathan Litman, Bennett Lorber, Ruth Ann Luna, Conan MacDougall, Rob Roy, Philip A. Mackowiak, Lawrence C. Madoff, Alan J. Magill, James H. Maguire, Frank Maldarelli, Lewis Markoff, Jeanne M. Marrazzo, Thomas J. Marrie, Thomas Marth, David H. Martin, Gregory J. Martin, Francisco M. Marty, Melanie Jane Maslow, Henry Masur, Alison Mawle, Kenneth H. Mayer, John T. McBride, James S. McCarthy, William M. McCormack, Catherine C. McGowan, Kenneth McIntosh, Paul S. Mead, Malgorzata Mikulska, Robert F. Miller, Samuel I. Miller, David H. Mitchell, John F. Modlin, Rajal K. Mody, Robert C. Moellering, Matthew Moffa, Susan Moir, José G. Montoya, Thomas A. Moore, Philippe Moreillon, J. Glenn Morris, Caryn Gee Morse, Robin Moseley, Robert S. Munford, Edward L. Murphy, Timothy F. Murphy, Barbara E. Murray, Clinton K. Murray, Patrick R. Murray, Daniel M. Musher, Jerod L. Nagel, Esteban C. Nannini, Anna Narezkina, Theodore E. Nash, William M. Nauseef, Jennifer L. Nayak, Marguerite A. Neill, Judith A. O'Donnell, Christopher A. Ohl, Pablo C. Okhuysen, Andrew B. Onderdonk, Steven M. Opal, Walter A. Orenstein, Douglas R. Osmon, Michael T. Osterholm, Stephen M. Ostroff, Michael N. Oxman, Slobodan Paessler, Andrea V. Page, Manjunath P. Pai, Tara N. Palmore, Raj Palraj, Peter G. Pappas, Mark S. Pasternack, Thomas F. Patterson, Deborah Pavan-Langston, David A. Pegues, Robert L. Penn, John R. Perfect, Stanley Perlman, Brett W. Petersen, Phillip K. Peterson, William A. Petri, Cathy A. Petti, Jennifer A. Philips, Julie V. Philley, Michael Phillips, Larry K. Pickering, Peter Piot, Jason M. Pogue, Aurora Pop-Vicas, Cynthia Portal-Celhay, John H. Powers, Richard N. Price, Yok-Ai Que, Justin D. Radolf, Sanjay Ram, Didier Raoult, Jonathan I. Ravdin, Stuart C. Ray, Annette C. Reboli, Marvin S. Reitz, David A. Relman, Cybèle A. Renault, Angela Restrepo, John H. Rex, Elizabeth G. Rhee, Norbert J. Roberts, José R. Romero, Alan L. Rothman, Craig R. Roy, Kathryn L. Ruoff, Mark E. Rupp, Charles E. Rupprecht, Thomas A. Russo, William A. Rutala, Edward T. Ryan, Amar Safdar, Mohammad M. Sajadi, Juan C. Salazar, Juan Carlos Sarria, Maria C. Savoia, Paul E. Sax, W. Michael Scheld, Joshua T. Schiffer, David Schlossberg, Thomas Schneider, Anne Schuchat, Jane R. Schwebke, Cynthia L. Sears, Leopoldo N. Segal, Parham Sendi, Kent A. Sepkowitz, Edward J. Septimus, Alexey Seregin, Stanford T. Shulman, George K. Siberry, Omar K. Siddiqi, Costi D. Sifri, Michael S. Simberkoff, Francesco R. Simonetti, Kamaljit Singh, Nina Singh, Upinder Singh, Scott W. Sinner, Sumathi Sivapalasingam, Leonard N. Slater, A. George Smulian, Jack D. Sobel, M. Rizwan Sohail, David E. Soper, Tania C. Sorrell, James M. Steckelberg, Allen C. Steere, Neal H. Steigbigel, James P. Steinberg, David S. Stephens, Timothy R. Sterling, David A. Stevens, Dennis L. Stevens, Jacob Strahilevitz, Charles W. Stratton, Anthony F. Suffredini, Kathryn N. Suh, Mark S. Sulkowski, Morton N. Swartz, Thomas R. Talbot, C. Sabrina Tan, Ming Tan, Chloe Lynne Thio, David L. Thomas, Lora D. Thomas, Stephen J. Thomas, Anna R. Thorner, Angela María Tobón, Edmund C. Tramont, John J. Treanor, Jason Trubiano, Athe M.N. Tsibris, Allan R. Tunkel, Ronald B. Turner, Kenneth L. Tyler, Ahmet Uluer, Diederik van de Beek, Walter J.F.M. van der Velden, Edouard G. Vannier, Trevor C. Van, James Versalovic, Claudio Viscoli, Ellen R. Wald, Matthew K. Waldor, David H. Walker, Richard J. Wallace, Edward E. Walsh, Stephen R. Walsh, Peter D. Walzer, Christine A. Wanke, Cirle A. Warren, Ronald G. Washburn, Valerie Waters, David J. Weber, Michael D. Weiden, Geoffrey A. Weinberg, Daniel J. Weisdorf, Louis M. Weiss, David F. Welch, Thomas E. Wellems, Richard P. Wenzel, Melinda Wharton, A. Clinton White, Richard J. Whitley, Walter R. Wilson, Glenn W. Wortmann, William F. Wright, Jo-Anne H. Young, Vincent B. Young, Nadezhda Yun, Werner Zimmerli, Stephen H. Zinner, and John J. Zurlo

Published
2015

153. Orthopedic Implant–Associated Infections

Author

Parham Sendi and Werner Zimmerli

Subjects
medicine.medical_specialty, External fixation, business.industry, medicine.medical_treatment, Medicine, Internal fixation, Orthopedic implant, business, Surgery
Published
2015

154. Genotypic and phenotypic resistance testing of HIV-1 in routine clinical care

Author

Thomas Klimkait, Katarina Petrovic, A. Holbro, Henning Drechsler, Parham Sendi, Hans H. Hirsch, François Hamy, and Manuel Battegay

Subjects
Adult, Male, Microbiology (medical), medicine.medical_specialty, Nevirapine, Genotype, Anti-HIV Agents, Population, HIV Infections, Drug resistance, Biology, Ambulatory Care Facilities, Indinavir, Internal medicine, Drug Resistance, Viral, medicine, Humans, education, Didanosine, Aged, education.field_of_study, food and beverages, Lamivudine, Lopinavir, General Medicine, Middle Aged, Viral Load, Phenotype, Infectious Diseases, Immunology, HIV-1, Female, Viral load, medicine.drug
Abstract

Data on genotypic and phenotypic resistance testing of HIV-1 in the routine clinical setting are lacking. In a retrospective single-center study, all patients (n = 102) for whom genotypic resistance typing (GRT) and phenotypic resistance typing (PRT) were performed during the calendar year 2002 were examined. GRT and PRT results were concordant for 79% of the drugs, being highest for nevirapine (92%) and lowest for didanosine (57%). Concordance of results for protease inhibitors was lowest for lopinavir (78%) and highest for indinavir (88%). Discordant results for lamivudine were observed in 16% of patients; 90% of these results corresponded to high-level resistance by PRT and susceptibility by GRT. Overall, HIV loads were lower and CD4+ cell counts higher after therapy following resistance testing, but a significant association with the number of active drugs as predicted by GRT or PRT could not be identified. In a subgroup of 43 patients with virological failure under antiretroviral therapy and sufficient follow-up data, HIV loads were significantly lower after 3 and 6 months. More patients with HIV loads

Published
2005

155. Percutaneous embolization of renal arteriovenous fistula

Author

Parham Sendi, D. Toia, and P. Nussbaumer

Subjects
medicine.medical_specialty, Percutaneous, Fistula, medicine.medical_treatment, Arteriovenous fistula, Nephrectomy, Renal Veins, Renal Artery, medicine.artery, Occlusion, Humans, Medicine, Embolization, Renal artery, Aged, business.industry, Arteriovenous malformation, Balloon Occlusion, medicine.disease, Abdominal Pain, Surgery, Treatment Outcome, Arteriovenous Fistula, Female, Radiology, Cardiology and Cardiovascular Medicine, business
Abstract

Acquired renal arteriovenous fistula is a rare complication following a nephrectomy and its diagnosis may be made many years after the intervention. The closure of the fistula is advisable in most cases, since it represents a risk for heart failure and rupture of the vessel. There are an increasing number of publications describing different techniques of occlusion. The case of a 70-year-old woman with abdominal discomfort due to a large renal arteriovenous fistula, 45 years after nephrectomy, is presented and current literature is reviewed. Percutaneous embolization was performed by placing an occluding balloon through the draining vein followed by the release of nine coils through arterial access. One day after successful occlusion of the fistula, clinical symptoms disappeared.

Published
2005

156. Mycobacterium tuberculosis and prosthetic joint infection

Author

Andrew Brent and Parham Sendi

Subjects
medicine.medical_specialty, Prosthesis-Related Infections, Tuberculosis, biology, business.industry, Antitubercular Agents, Prosthetic joint infection, Mycobacterium tuberculosis, biology.organism_classification, medicine.disease, Tuberculosis, Osteoarticular, 03 medical and health sciences, 0302 clinical medicine, Infectious Diseases, Internal medicine, Medicine, 030212 general & internal medicine, Prosthesis-Related Infection, business, 030217 neurology & neurosurgery
Published
2016

157. Infective endocarditis caused by Group B Streptococcus: The role of aminoglycoside-combination

Author

Mattias Ericsson, Lars Olaison, and Parham Sendi

Subjects
Male, Microbiology (medical), medicine.medical_specialty, Treatment outcome, medicine.disease_cause, Group B, Streptococcus agalactiae, Pharmacotherapy, Streptococcal Infections, Internal medicine, Humans, Medicine, Aged, Endocarditis, business.industry, Streptococcus, Aminoglycoside, Middle Aged, medicine.disease, HACEK endocarditis, Anti-Bacterial Agents, Aminoglycosides, Treatment Outcome, Infectious Diseases, Infective endocarditis, Drug Therapy, Combination, Female, business, Combination method
Published
2012

158. Disseminated cryptococcal infection in a patient who had kidney transplant: discrepancy between clinical symptoms and microbiological findings

Author

Niklaus von Steiger, Parham Sendi, Suzan Dahdal, and Robert M. Kalicki

Subjects
Adult, Male, drugs and medicines, Pathology, medicine.medical_specialty, Fever, renal medicine, 030232 urology & nephrology, 610 Medicine & health, White, Meningitis, Cryptococcal, Kidney transplant, immunology, 03 medical and health sciences, Postoperative Complications, 0302 clinical medicine, Cerebrospinal fluid, medicine, Viral meningitis, Humans, renal system, 030212 general & internal medicine, renal intervention, Kidney transplantation, Fungemia, Cryptococcus neoformans, biology, business.industry, Headache, General Medicine, medicine.disease, Meningeal irritation, biology.organism_classification, Kidney Transplantation, Reminder of Important Clinical Lesson, 19-30 years, 570 Life sciences, Cryptococcal meningitis, business, Europe (West)
Abstract

A 29-year-old man complained of a 2-day history of frontal headache and new-onset fever but no other symptoms. Two months prior to admission, he underwent his third kidney transplantation. Clinical and laboratory examinations were unremarkable. Brain MRI showed a meningeal irritation consistent with viral meningitis. A diagnosis of cryptococcal meningitis and fungaemia was made after detection of a remarkably high and visible load of Cryptococcus neoformans in the cerebrospinal fluid.

Published
2017

159. Association between capsular serotype V and macrolide resistance in group B Streptococcus

Author

Parham Sendi and Simone Fröhlicher

Subjects
Serotype, Epidemiology, 610 Medicine & health, Microbial Sensitivity Tests, Biology, medicine.disease_cause, Group B, Infant, Newborn, Diseases, Microbiology, Streptococcus agalactiae, Cohort Studies, Japan, Streptococcal Infections, Correspondence, Drug Resistance, Bacterial, medicine, Humans, Serotyping, Phylogeny, Bacterial Capsules, Streptococcus, Infant, Newborn, Infant, Original Papers, Anti-Bacterial Agents, Infectious Diseases, Macrolide resistance, 570 Life sciences, biology, Macrolides, Multilocus Sequence Typing
Abstract

SUMMARY Streptococcus agalactiae (group B streptococcus; GBS) isolates (n = 150) from infants with invasive infections between 2006 and 2011 were analysed for capsular serotype, multilocus sequence type, and antibiotic susceptibility. In cases with late-onset disease (n = 115), primary meningitis was predominant (62.6%), but represented only 39.1% in cases with early-onset disease (n = 23). The most common serotype was III (58.7%), followed by Ia (21.3%) and Ib (12.7%). Sequence types (STs) of serotype III strains included ST17 (50.0%), ST19 (26.1%), ST335 (18.2%), ST27 (4.5%), and ST1 (1.1%). Predominant STs of serotypes Ia and Ib were ST23 (81.3%) and ST10 (84.2%), respectively. No penicillin-resistant strains were detected, but 22·0% of strains had mef(A/E), erm(A), or erm(B) genes, which mediate macrolide resistance. A new ST335, possessing an mef(A/E) gene belonging to clonal complex 19 gradually increased in frequency. Improved prevention of invasive GBS infections in infants requires timely identification, and ultimately vaccine development.

Published
2014

160. The treatment and outcome of peri-prosthetic infection of the ankle: a single cohort-centre experience of 34 cases

Author

Werner Zimmerli, Markus Knupp, Benedikt M. Kessler, Parham Sendi, Peter Graber, Beat Hintermann, and Lukas Zwicky

Subjects
Joint Instability, Male, Reoperation, medicine.medical_specialty, Prosthesis-Related Infections, Time Factors, medicine.medical_treatment, Arthrodesis, Joint Prosthesis, Ankle replacement, Risk Assessment, Cohort Studies, Arthroplasty, Replacement, Ankle, Medicine, Humans, Orthopedics and Sports Medicine, Range of Motion, Articular, Prosthetic infection, Aged, Pain Measurement, Retrospective Studies, business.industry, Soft tissue, Middle Aged, Arthroplasty, Surgery, Anti-Bacterial Agents, medicine.anatomical_structure, Treatment Outcome, Cohort, Drainage, Female, Ankle, business, Follow-Up Studies
Abstract

The treatment of peri-prosthetic joint infection (PJI) of the ankle is not standardised. It is not clear whether an algorithm developed for hip and knee PJI can be used in the management of PJI of the ankle. We evaluated the outcome, at two or more years post-operatively, in 34 patients with PJI of the ankle, identified from a cohort of 511 patients who had undergone total ankle replacement. Their median age was 62.1 years (53.3 to 68.2), and 20 patients were women. Infection was exogenous in 28 (82.4%) and haematogenous in six (17.6%); 19 (55.9%) were acute infections and 15 (44.1%) chronic. Staphylococci were the cause of 24 infections (70.6%). Surgery with retention of one or both components was undertaken in 21 patients (61.8%), both components were replaced in ten (29.4%), and arthrodesis was undertaken in three (8.8%). An infection-free outcome with satisfactory function of the ankle was obtained in 23 patients (67.6%). The best rate of cure followed the exchange of both components (9/10, 90%). In the 21 patients in whom one or both components were retained, four had a relapse of the same infecting organism and three had an infection with another organism. Hence the rate of cure was 66.7% (14 of 21). In these 21 patients, we compared the treatment given to an algorithm developed for the treatment of PJI of the knee and hip. In 17 (80.9%) patients, treatment was not according to the algorithm. Most (11 of 17) had only one criterion against retention of one or both components. In all, ten of 11 patients with severe soft-tissue compromise as a single criterion had a relapse-free survival. We propose that the treatment concept for PJI of the ankle requires adaptation of the grading of quality of the soft tissues. Cite this article: Bone Joint J 2014;96-B:772–7.

Published
2014

161. Primary sternal tuberculosis: a case report and review of the literature

Author

Myriam Marcelle Eyer, Mihai A. Constantinescu, and Parham Sendi

Subjects
Microbiology (medical), medicine.medical_specialty, Pediatrics, Tuberculosis, biology, business.industry, Extrapulmonary tuberculosis, Osteoarticular tuberculosis, 610 Medicine & health, Case presentation, Antituberculous drugs, medicine.disease, biology.organism_classification, Microbiology, Surgery, Mycobacterium tuberculosis, medicine.anatomical_structure, medicine, Sternal osteomyelitis, business, Sinus (anatomy)
Abstract

Introduction: Primary sternal osteomyelitis caused by Mycobacterium tuberculosis is a rare manifestation of extrapulmonary tuberculosis. Case presentation: We present a case of isolated sternal tuberculosis and review the demographic, clinical, diagnostic and therapeutic features of 32 published cases found in a systematic review of the literature. Patients with primary sternal osteomyelitis due to M. tuberculosis are often young and have no co‐morbidity. Diagnosis is frequently delayed. Common symptoms and signs are local swelling and a discharging sinus tract. Patients frequently have at least one systemic symptom, including fever, weight loss and night sweats. Our case and half of those found in the literature review were successfully treated with antituberculous drugs alone. Conclusion: Treatment concepts for primary sternal tuberculosis are not established and are often derived from those of osteoarticular tuberculosis. These data point towards an interdisciplinary concept without surgery.

Published
2014

162. HMGB1 in severe soft tissue infections caused by Streptococcus pyogenes

Author

Pontus Thulin, Parham Sendi, Linda Johansson, Carl-Johan Treutiger, Johanna Snäll, Anna Linnér, Anna Norrby-Teglund, and Adam Linder

Subjects
Microbiology (medical), Necrosis, Streptococcus pyogenes, Biopsy, Immunology, lcsh:QR1-502, 610 Medicine & health, Inflammation, chemical and pharmacologic phenomena, Biology, medicine.disease_cause, Microbiology, Erysipelas, lcsh:Microbiology, Microbiology in the medical area, In vivo, Streptococcal Infections, Image Processing, Computer-Assisted, medicine, Humans, Original Research Article, Fasciitis, Necrotizing, HMGB1 Protein, Fasciitis, HMGB1, Microscopy, Microscopy, Confocal, medicine.diagnostic_test, Soft Tissue Infections, Optical Imaging, Cellulitis, medicine.disease, Immunohistochemistry, 3. Good health, Infectious Diseases, medicine.symptom
Abstract

Extracellular High Mobility Group Box 1 (HMGB1) has been associated with acute and chronic inflammatory conditions. However, little is known about HMGB1 in necrotizing bacterial infections. We hypothesized that the local HMGB1 response is excessive in severe soft tissue infections, which are characterized by necrosis and hyperinflammation. To explore this, tissue biopsies were collected from patients with varying severity of Streptococcus pyogenes skin and soft tissue infections, including erysipelas, cellulitis, and necrotizing fasciitis. Tissue sections were immunostained for HMGB1, S. pyogenes, and inflammatory cell infiltrates and results quantified by acquired computerized image analysis. HMGB1 expression increased in parallel to disease severity and was significantly higher in necrotizing fasciitis than in erysipelas (p=0.0023). Confocal microscopy of sections co-stained for HMGB1 and cell markers revealed both extracellular and cytoplasmic HMGB1, the latter of which was found predominantly in macrophages. To further verify macrophages as main source of activation triggered HMGB1 release, human macrophages were infected with clinical S. pyogenes isolates. The results demonstrated infection triggered release of HMGB1. Dual staining’s visualized HMGB1 in areas close to, but not overlapping, with neutrophils, indicating a potential chemotactic role. In vitro transmigration experiments showed a chemotactic effect of HMGB1 on neutrophils. The data furthermore provided in vivo support that HGMB1 may form immunostimulatory complexes with IL-1β. Taken together, the findings provide the first in vivo evidence that HMGB1 is abundant at the local site of severe bacterial soft tissue infections and its levels correlated to severity of infections; hence, indicating its potential value as a biomarker for tissue pathology.

Published
2014

163. The many faces of a lungvirus

Author

Mirjam De Roche and Parham Sendi

Subjects
Microbiology (medical), Lung, biology, business.industry, Symptomatic treatment, 610 Medicine & health, medicine.disease, biology.organism_classification, Microbiology, Virology, Virus, medicine.anatomical_structure, Human metapneumovirus, Lower respiratory tract infection, medicine, business
Published
2014

164. Cost-effectiveness of anterior implants versus fixed dental prostheses

Author

Gabriel Krastl, Nicola U. Zitzmann, Parham Sendi, Sebastian Kühl, and Roland Weiger

Subjects
Cost effectiveness, Visual analogue scale, medicine.medical_treatment, Cost-Benefit Analysis, Clinical Investigations, Dentistry, Esthetics, Dental, Patient satisfaction, Dental Implants, Single-Tooth, stomatognathic system, Dental Prosthesis Design, Medicine, Humans, Longitudinal Studies, Prospective Studies, Denture Design, General Dentistry, Probability, Orthodontics, Stochastic Processes, Crowns, Missing tooth, business.industry, Jaw, Edentulous, Partially, Patient Preference, Patient preference, Quality-adjusted life year, Patient Satisfaction, Costs and Cost Analysis, Denture, Partial, Fixed, Dental Prosthesis, Implant-Supported, Quality-Adjusted Life Years, business, Dental restoration, Follow-Up Studies
Abstract

For the restoration of an anterior missing tooth, implant-supported single crowns (ISCs) or fixed dental prostheses (FDPs) are indicated, but it is not clear which type of restoration is more cost-effective. A self-selected trial was performed with 15 patients with ISCs and 11 with FDPs. Patient preferences were recorded with visual analog scales before treatment, 1 month following restoration, and then annually. Quality-adjusted tooth years (QATYs) were estimated by considering the type of reconstruction for replacing the missing tooth and its effect on the adjacent teeth. A stochastic cost-effectiveness model was developed using Monte Carlo simulation. The expected costs and QATYs were summarized in cost-effectiveness acceptability curves. ISC was the dominant strategy, with a QATY increase of 0.01 over 3 years and 0.04 over 10 years with a higher probability of being cost-effective. While both treatment options provided satisfactory long-term results from the patient’s perspective, the lower initial costs, particularly laboratory fees, were responsible for the dominance of ISCs over FDPs.

Published
2013

167. The cost-effectiveness of different management strategies for Type I diabetes: a Swiss perspective

Author

K. Neeser, A Brandt, C. Weiss, Parham Sendi, H. Wenzel, Giatgen A. Spinas, Andrew J. Palmer, and G. Singh

Subjects
medicine.medical_specialty, Pediatrics, Cost effectiveness, Cost-Benefit Analysis, Endocrinology, Diabetes and Metabolism, End stage renal disease, Life Expectancy, Diabetes management, Diabetes mellitus, Internal Medicine, medicine, Albuminuria, Humans, Insulin, Mass Screening, Diabetic Nephropathies, Cumulative incidence, Mass screening, Diabetic Retinopathy, Models, Statistical, business.industry, Incidence, Diabetic retinopathy, medicine.disease, Markov Chains, Surgery, Diabetes Mellitus, Type 1, Life expectancy, Kidney Failure, Chronic, business, Diabetic Angiopathies, Switzerland
Abstract

Aims/hypothesis. A computer model was developed to determine the health outcomes and economic consequences of different combinations of diabetes interventions in newly diagnosed patients with Type I (insulin-dependent) diabetes in Switzerland.¶Methods. We modelled seven complications of diabetes: hypoglycaemia, ketoacidosis, acute myocardial infarction, stroke, lower extremity amputation, nephropathy, and retinopathy. Transition probabilities and costs were taken from published literature. The Swiss health insurance payer perspective was taken. Various combinations of diabetes management strategies, including intensive or conventional insulin therapy and screening and treatment strategies for renal and eye disease were defined. Life expectancy, cumulative incidences of complications, and mean expected total lifetime costs per patient were calculated under six different management strategies. Incremental cost-effectiveness ratios were calculated in terms of costs per life-year gained compared with conventional insulin therapy alone.¶Results. The addition of screening for microalbuminuria and retinopathy followed by appropriate treatment, if detected, were cost saving, with reduction in cumulative incidence of end stage renal disease and blindness respectively, and, in the case of microalbuminuria screening and treatment, an improvement in life expectancy. Intensive therapy improved life expectancy but increased total lifetime costs.¶Conclusion/interpretation. Optimal management of Type I diabetic patients, including secondary and tertiary prevention, leads to reduced complications and improved life expectancy, with the increased costs of prevention offset to varying degrees by cost savings due to complications avoided. [Diabetologia (2000) 43: 13–26]

Published
2000

168. Broad-Range PCR in Selected Episodes of Prosthetic Joint Infection

Author

Parham Sendi, M. Lüem, Peter E. Ochsner, Werner Zimmerli, F. H. R. De Man, and Peter Graber

Subjects
Microbiology (medical), medicine.medical_specialty, Infectious Diseases, medicine, Colony count, Prosthetic joint infection, General Medicine, Biology, Surgery
Published
2009

169. Rare AIDS-Defining Diseases in the Swiss HIV Cohort Study

Author

Dominik Pfluger, Manuel Battegay, Heiner C. Bucher, Jürgen Drewe, Parham Sendi, Gyr N, Reto Nüesch, Werner Zimmerli, and B. Burckhardt

Subjects
Adult, Male, Microbiology (medical), Pathology, medicine.medical_specialty, AIDS-Related Opportunistic Infections, Isosporiasis, Disseminated coccidioidomycosis, Disease, Meningitis, Cryptococcal, Cohort Studies, Prevalence, medicine, Humans, Prospective Studies, Prospective cohort study, Demography, Lymphoma, AIDS-Related, Mycobacterium kansasii, Acquired Immunodeficiency Syndrome, biology, Brain Neoplasms, business.industry, Progressive multifocal leukoencephalopathy, Leukoencephalopathy, Progressive Multifocal, Herpes Simplex, Cryptococcosis, General Medicine, medicine.disease, biology.organism_classification, Dermatology, CD4 Lymphocyte Count, Infectious Diseases, Female, business, Switzerland
Abstract

The objective of this study was to investigate the spectrum and frequency of rare AIDS-defining diseases in the Swiss HIV Cohort Study. AIDS-defining diseases contributing less than 1% to the absolute number of all recorded AIDS-defining diseases in at least one of five periods (1988-1990, 1991-1992, 1993-1994, 1995-1996, 1997) were defined as being rare. A total of 9110 HIV-infected subjects were included in this study. Over the entire 9-year period, the following rare diseases were diagnosed: progressive multifocal leukoencephalopathy (n = 138), disseminated cryptococcosis (n = 67), visceral herpes simplex disease (n = 66), primary cerebral lymphoma (n = 65), indeterminate cerebral lesion (n = 50), cryptococcal meningitis (n = 34), Mycobacterium kansasii disease (n = 32), recurrent Salmonella septicemia (n = 22), intestinal isosporiasis (n = 21), candidiasis of the trachea, bronchi and lungs (n = 19), toxoplasma retinitis (n = 16), disseminated toxoplasmosis (n = 8), invasive cervical carcinoma (n = 8), extrapulmonary Pneumocystis disease (n = 5), disseminated histoplasmosis (n = 1) and disseminated coccidioidomycosis (n = 1). Rare diseases accounted for 7.3% of all AIDS-defining diseases over the entire 9-year period. Physicians should be aware of the likelihood of a broad spectrum of AIDS-defining diseases in HIV-infected patients.

Published
1999

170. Dynamics of serum procalcitonin in patients after major neurosurgery

Author

Peter Graber, P. Huber, Ursula Flückiger, Parham Sendi, Gerd Laifer, O. Gratzl, M. Wasner, and Werner Zimmerli

Subjects
Adult, Calcitonin, Male, Microbiology (medical), medicine.medical_specialty, Pathology, Calcitonin Gene-Related Peptide, Neurosurgery, Inflammation, Fever of Unknown Origin, Gastroenterology, Neurosurgical Procedures, Procalcitonin, post-operative, Central nervous system disease, Internal medicine, Diagnosis, parasitic diseases, medicine, Humans, In patient, Protein Precursors, Fever of unknown origin, Aged, business.industry, meningitis, General Medicine, Middle Aged, medicine.disease, procalcitonin levels, Infectious Diseases, Female, Reagent Kits, Diagnostic, medicine.symptom, business, Meningitis, Biomarkers
Abstract

Classical markers of infection cannot differentiate reliably between inflammation and infection after neurosurgery. This study investigated the dynamics of serum procalcitonin (PCT) in patients following major neurosurgery. PCT concentrations remained < 0.2 ng /mL during the postoperative course. In contrast, leukocyte and neutrophil counts, as well as C-reactive protein (CRP) levels, increased significantly post-operatively (leukocytes, range 7.1–23.7 × 109/L, p < 0.001; neutrophils, range 70.8–94.5%, p < 0.001; CRP, median 14 mg/L, range 3–95 mg/L, p < 0.001). Analysis of PCT levels using assays with improved sensitivity may be useful in the diagnosis of neurosurgical patients with post-operative fever of unknown origin.

Published
2005

171. An MEKC assay for the therapeutic drug monitoring of cefepime

Author

Regula, Theurillat, Parham, Sendi, and Wolfgang, Thormann

Subjects
Quality Control, Calibration, Humans, Drug Monitoring, Cefepime, Anti-Bacterial Agents, Cephalosporins, Chromatography, Micellar Electrokinetic Capillary
Abstract

The development of a robust assay based on MEKC for cefepime in human serum and plasma with internal quality assurance is reported. Sample preparation comprises protein precipitation in the presence of SDS at pH 4.5. This is a gentle approach for which decomposition of cefepime during sample handling is negligible. After hydrodynamic sample injection of the supernatant, analysis occurs in a phosphate/borate buffer at pH 9.1 with 75 mM SDS using normal polarity and analyte detection at 257 nm. The MEKC run time interval and throughput are about 5 min and seven samples per hour, respectively. The calibration range for cefepime is 1-60 μg/mL, with 1 μg/mL being the LOQ. The performance of the assay with multilevel internal calibration was assessed with calibration and control samples. The assay is shown to be simple, inexpensive, reproducible, and robust. It was applied to determine cefepime levels in the sera of critically ill patients and to assess the instability of cefepime in patient and control samples. Our data revealed that serum containing cefepime can be stored at -20°C for a short time, whereas for long-term storage, samples have to be kept at -70°C.

Published
2013

172. Non-phenotypic tests to detect and characterize antibiotic resistance mechanisms in Enterobacteriaceae

Author

Andrea Endimiani, Krisztina M. Papp-Wallace, Agnese Lupo, Robert A. Bonomo, and Parham Sendi

Subjects
Microbiology (medical), biology, Microarray, medicine.drug_class, Antibiotics, Cephalosporin, Enterobacteriaceae Infections, General Medicine, Microbial Sensitivity Tests, Antimicrobial, biology.organism_classification, Enterobacteriaceae, Article, Mass Spectrometry, Microbiology, Infectious Diseases, Antibiotic resistance, Molecular Diagnostic Techniques, medicine, Humans, 570 Life sciences, Multiplex, DNA microarray, 610 Medicine & health
Abstract

In the past two decades, we have observed a rapid increase of infections due to multidrug-resistant Enterobacteriaceae. Regrettably, these isolates possess genes encoding for extended-spectrum β-lactamases (e.g., blaCTX-M, blaTEM, blaSHV) or plasmid-mediated AmpCs (e.g., blaCMY) that confer resistance to last-generation cephalosporins. Furthermore, other resistance traits against quinolones (e.g., mutations in gyrA and parC, qnr elements) and aminoglycosides (e.g., aminoglycosides modifying enzymes and 16S rRNA methylases) are also frequently co-associated. Even more concerning is the rapid increase of Enterobacteriaceae carrying genes conferring resistance to carbapenems (e.g., blaKPC, blaNDM). Therefore, the spread of these pathogens puts in peril our antibiotic options. Unfortunately, standard microbiological procedures require several days to isolate the responsible pathogen and to provide correct antimicrobial susceptibility test results. This delay impacts the rapid implementation of adequate antimicrobial treatment and infection control countermeasures. Thus, there is emerging interest in the early and more sensitive detection of resistance mechanisms. Modern non-phenotypic tests are promising in this respect, and hence, can influence both clinical outcome and healthcare costs. In this review, we present a summary of the most advanced methods (e.g., next-generation DNA sequencing, multiplex PCRs, real-time PCRs, microarrays, MALDITOF MS, and PCR/ESI MS) presently available for the rapid detection of antibiotic resistance genes in Enterobacteriaceae. Taking into account speed, manageability, accuracy, versatility, and costs, the possible settings of application (research, clinic, and epidemiology) of these methods and their superiority against standard phenotypic methods are discussed.

Published
2013
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173. Antimicrobial treatment concepts for orthopaedic device-related infection

Author

Parham Sendi and Werner Zimmerli

Subjects
Microbiology (medical), medicine.medical_specialty, Prosthesis-Related Infections, daptomycin, linezolid, Staphylococcal infections, Joint infections, chemistry.chemical_compound, medicine, Humans, Surgical treatment, Intensive care medicine, Clinical Trials as Topic, orthopaedic device-related infection, business.industry, Orthopaedic device, rifamycin derivatives, General Medicine, Bacterial Infections, Antimicrobial, medicine.disease, Bone penetration, Surgery, Anti-Bacterial Agents, Infectious Diseases, Treatment Outcome, chemistry, Debridement, Linezolid, Vancomycin, Daptomycin, business, rifampin, medicine.drug
Abstract

Successful management of orthopaedic device-related infections requires combined surgical and antimicrobial therapy. Because of the heterogeneity of clinical situations, controlled trials are lacking. Although rational concepts for surgical treatment have been published, many aspects of antimicrobial therapy are still not well documented. In this review, some of these knowledge gaps are discussed, and rational arguments for initial parenteral treatment are presented. In addition, the interpretation of data regarding bone penetration is discussed. Whereas rifampin is now a standard combination partner in the treatment of staphylococcal infections, its role against other microorganisms is still unclear. Finally, in view of the increasing prevalence of methicillin-resistant staphylococci and their decreasing susceptibility to vancomycin, data are provided on linezolid and daptomycin, which can potentially be used in bone and joint infections.

Published
2012

174. Subarachnoid Hemorrhage, Aneurysmal

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

175. Supraventricular Arrhythmias

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

176. Septic Ovarian Vein Thrombophlebitis

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

177. SBP

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

178. Sepsis: Etiologies

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

179. Supplemental Parenteral Nutrition (SPN)

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

180. Secondary Compartment Syndrome

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

181. Substitution Fluid

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

182. Systolic Dysfunction

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

183. Stroke, Blood Pressure Management

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

184. Synthetic Polymers

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

185. SARS CoV Infection

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

186. Systemic Inflammatory Response Syndrome (SIRS) with Infection

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

187. Second-Degree Burn

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

188. Sepsis, Overview

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

189. Systemic Air Embolism

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

190. Stroke Volume Variation (SVV)

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

191. Splenic Arteriovenous Fistula

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

192. Sepsis-induced Acute Kidney Injury

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

193. Snake Bites

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

194. Severe Acute Respiratory Syndrome, Viral (SARS)

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

195. Septic Thrombophlebitis

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

196. Streptococcal Gangrene

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

197. Spinal Shock

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

198. Spleen, Nonoperative Management

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

199. Subarachnoid Monitor

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

200. ST-Segment Elevation Myocardial Infarction

Author

John Kashani, Richard D. Shih, Thomas H. Cogbill, David H. Jang, Lewis S. Nelson, Mitchell M. Levy, Margaret M. Parker, Diego Castanares-Zapatero, Pierre-François Laterre, Joseph B. Barney, Edward Abraham, Raghavan Murugan, John A. Kellum, R. Sonneville, E. Wesley Ely, Tarek Sharshar, Dushyant Maharaj, Stefan Herget-Rosenthal, Stephen E. Lapinsky, Irshad H. Chaudry, Martin K. Angele, Alfred B. Cheng, Anthony J. Dean, Sonja Hansen, Elisabeth Meyer, B. J. Biemond, Dean Olsen, Neesh Pannu, Dennis L. Stevens, Amy E. Bryant, Tanyalak Parimon, Zhongping Huang, William R. Clark, Claudio Ronco, Daniel G. Boutsikaris, Michael E. Winters, Eric M. Massicotte, Charles Tator, Philip F. Stahel, Michael A. Flierl, Todd F. VanderHeiden, Kathryn M. Beauchamp, Demetrios Demetriades, Andrew B. Peitzman, Anna Wilkes, David H. Wisner, Mark A. Malangoni, Richard J. Mullins, Marya D. Zilberberg, Andrew F. Shorr, Andrea O. Rossetti, Kenneth L. Mattox, Parham Sendi, Mihai A. Constantinescu, Charles Feldman, Ronald Anderson, Erin McDonough Grise, Bryn E. Mumma, Deborah B. Diercks, Richard E. Temes, Parita Bhuva, Barnett R. Nathan, Ken R. Winston, Daniel Backer, Jacques Creteur, Juan A. Asensio, Aytekin Unlu, C. Sousa, Susanna Price, and Benjamin Sun

Published
2012

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