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153. 17 - Epi-LASIK

Author

Katsanevaki, Vikentia J., Kalyvianaki, Maria I., Naoumidi, Irini I., and Pallikaris, Ioannis G.

Published
2007
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160. Anterior Segment Applications of In Vivo Confocal Microscopy.

Author

Kymionis, George D., Diakonis, Vasilios F., Shehadeh, Mohammad M., Pallikaris, Aristofanis I., and Pallikaris, Ioannis G.

Subjects
CONFOCAL microscopy, MICROSCOPY, CONFOCAL fluorescence microscopy, ANTERIOR eye segment, EYE
Abstract

Purpose: To review the current literature on in vivo confocal microscopy anterior segment applications (cornea, conjunctiva, and glaucoma) and discuss its advantages in different pathological conditions. Methods: Review of selected relevant literature on in vivo confocal microscopy and its different applications. Results: In vivo confocal microscopy can be used to visualize most layers of the cornea and conjunctiva, providing excellent resolution. In the past, it was mainly utilized as a research tool; lately there seems to be an increasing interest for clinical applications; confocal microscopy aids the diagnosis and follow-up of many anterior segment disorders, such as corneal dystrophies, corneal and conjunctival inflammatory and neoplastic diseases, glaucoma patients, and assessment of surgical procedures. Conclusion: In vivo confocal microscopy is an important addition to the ophthalmic diagnostic tools with several anterior segment applications. Its clinical applications are being continuously explored and are quickly expanding to cover many new pathological aspects. [ABSTRACT FROM AUTHOR]

Published
2015
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161. Prospective Comparison of Low-Fluence Photodynamic Therapy Combined with Intravitreal Bevacizumab versus Bevacizumab Monotherapy for Choroidal Neovascularization in Age-Related Macular Degeneration.

Author

Datseris, Ioannis, Kontadakis, Georgios A., Diamanti, Ramza, Datseris, Iordanis, Pallikaris, Ioannis G., Theodossiadis, Panagiotis, and Tsilimbaris, Miltiadis K.

Subjects
RETINAL degeneration, PHOTODYNAMIC therapy, VERTEPORFIN, BEVACIZUMAB, CLINICAL trials, TOMOGRAPHY, THERAPEUTICS
Abstract

Purpose: To evaluate combination treatment with reduced-fluence photodynamic therapy (RDPDT) with Verteporfin and intravitreal bevacizumab, compared to bevacizumab alone, for choroidal neovascularization (CNV) in age-related macular degeneration. Methods: This was a prospective, randomized comparative study comprising 95 patients with CNV. 49 patients received RDPDT (25 J/cm2) followed by intravitreal bevacizumab 1.25 mg one hour later, while 46 received intravitreal bevacizumab alone. Patients were followed for 12 months at four-week intervals with visual acuity (VA) assessment and Optical Coherence Tomography (OCT) of the macula. Bevacizumab re-injections were performed as needed. Results: On average, patients were re-injected 4.45 times in the combination group and 6.96 times in the bavacizumab group ( p < 0.001). At 12 months, VA improved by 8.64 letters in the bevacizumab group and by 8.37 letters in the combination group ( p = 0.922). Conclusion: Adding a reduced-fluence PDT arm in combination with bevacizumab offers similar results to those of intravitreal bevacizumab alone with significantly reduced number of injection repetitions. [ABSTRACT FROM AUTHOR]

Published
2015
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162. Reply

Author

Kymionis, George D., primary, Tsilimbaris, Miltiadis K., additional, and Pallikaris, Ioannis G., additional

Published
2006
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167. Apraclonidine and LASIK

Author

Aslanides, Ioannis M., primary, Tsiklis, Nikolaos S., additional, Pallikaris, Ioannis G., additional, Jankov, Mirko R., additional, Coskunseven, Efekan, additional, and Ozkilic, Efekan, additional

Published
2005
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181. Management of keratoconus with Intacs

Author

Siganos, Charalambos S, primary, Kymionis, George D, additional, Kartakis, Nikos, additional, Theodorakis, Michalis A, additional, Astyrakakis, Nikos, additional, and Pallikaris, Ioannis G, additional

Published
2003
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182. Phakic Intraocular Lenses for the Treatment of High Myopia.

Author

Tombran-Tink, Joyce, Barnstable, Colin J., Rizzo, Joseph F., Kalyvianaki, Maria I., Kymionis, George D., and Pallikaris, Ioannis G.

Abstract

High myopia remains a challenge for refractive surgeons. The use of laser in situ keratomileusis (LASIK), which has become increasingly popular for the treatment of myopia (1,2), is limited in high myopic eyes, because a residual corneal stromal thickness of 250 µm is essential to minimize the risk of corneal ectasia (3). Apart from that, large excimer laser corrections may result in poor optical quality of the reshaped cornea (4). Clear lens extraction, as another method for treating high refractive errors, results in accommodation loss, at the same time it carries all the risks of cataract surgery ((5)-(7)). An evolving technique for the treatment of myopia in young phakic patients is the implantation of phakic intraocular lenses (PIOLs). In this chapter the main types of these lenses, the criteria for their implantation, their advantages, and their possible complications will be discussed. [ABSTRACT FROM AUTHOR]

Published
2007
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196. Crete, Greece Glaucoma Study

Author

Kozobolis, Vassilios P., primary, Detorakis, Efstathios T., additional, Tsilimbaris, Miltiadis, additional, Siganos, Dimitrios S., additional, Vlachonikolis, Ioannis G., additional, and Pallikaris, Ioannis G., additional

Published
2000
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199. Long-term visual outcomes after Crystalens HD intraocular lens implantation.

Author

Karavitaki, Alexandra E., Pallikaris, Ioannis G., Panagopoulou, Sophia I., Kounis, George A., Kontadakis, George, and Kymionis, George D.

Subjects
*INTRAOCULAR lenses, *ARTIFICIAL implants, *CATARACT surgery, *SURGICAL complications, *VISUAL acuity
Abstract

Purpose: Our purpose was to evaluate the long-term visual outcomes after bilateral implantation of Crystalens® HD (Bausch and Lomb, Inc.) accommodative intraocular lenses. Methods: In this study, 25 patients (50 eyes) who underwent cataract surgery and bilateral Crystalens HD accommodative intraocular lens implantation were included. The Crystalens HD lens was implanted in the bag in both eyes, without any intra- or postoperative complications. The visual parameters measured before and after surgery were: uncorrected distance visual acuity, corrected distance visual acuity (CDVA) (using the Early Diabetic Retinopathy Study [EDTRS] logMAR charts), uncorrected intermediate visual acuity, and uncorrected near visual acuity using a Birkhäuser reading chart, at a distance of 66 cm and 33 cm for intermediate and near vision, respectively, directly illuminated by a lamp of 60 watts. After surgery, the patients were evaluated at 1, 3, 6, 12, 24, and 36 months. Results: The mean age was 68.70±7.1 (range: 54 to 83) years. The mean follow-up was 42.72±0.49 (range: 42.33 to 43.27) months. The uncorrected distance visual acuity improved from 0.56±0.41 (range: 0 to 2) preoperatively to 0.19±0.13 (range: 0 to 0.38) (logMAR scale) at the last follow-up visit, and the CDVA improved from 0.17±0.18 (range: 0 to 0.7) preoperatively to 0.05±0.05 (range: -0.02 to 0.22) at the last follow-up visit. No eyes lost lines of CDVA during the follow-up period, while 54% of patients gained one or more lines of CDVA. The uncorrected intermediate and near visual acuity was J2 or better in 71% and 69% of our patients, respectively. Conclusion: Crystalens HD implantation seems to provide an improvement in visual acuity for far, intermediate, and near distances. [ABSTRACT FROM AUTHOR]

Published
2014
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200. Simultaneous Conventional Photorefractive Keratectomy and Corneal Collagen Cross-linking for Pellucid Marginal Corneal Degeneration.

Author

Kymionis, George D., Grentzelos, Michael A., Plaka, Argyro D., Tsoulnaras, Konstantinos I., Kankariya, Vardhaman P., Shehadeh, Mohammad M., and Pallikaris, Ioannis G.

Abstract

PURPOSE: To present the results after simultaneous conventional photorefractive keratectomy combined with corneal collagen cross-linking for pellucid marginal corneal degeneration. [ABSTRACT FROM AUTHOR]

Published
2014
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