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151. Comparison of Health-Related Quality of Life Between Japanese and American Patients with Bladder Cancer as Measured by a Newly Developed Japanese Version of the Bladder Cancer Index

Author

Osawa, Takahiro, primary, Wei, John T., additional, Abe, Takashige, additional, Honda, Michitaka, additional, Rew, Karl T., additional, Dunn, Rod, additional, Yamada, Shuhei, additional, Furumido, Jun, additional, Kikuchi, Hiroshi, additional, Matsumoto, Ryuji, additional, Sato, Yasuyuki, additional, Harabayashi, Toru, additional, Takada, Norikata, additional, Minami, Keita, additional, Morita, Ken, additional, Kashiwagi, Akira, additional, Fukuhara, Shunichi, additional, Murai, Sachiyo, additional, Ito, Yoichi M., additional, Ogasawara, Katsuhiko, additional, and Shinohara, Nobuo, additional

Published
2021
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152. Oncologic outcomes of laparoscopic radical nephroureterectomy in conjunction with template-based lymph node dissection : An extended follow-up study

Author

1000010762536, Matsumoto, Ryuji, 1000010399842, Abe, Takashige, Takada, Norikata, Minami, Keita, 1000070301900, Harabayashi, Toru, Nagamori, Satoshi, Hatanaka, Kanako C., Yamashiro, Katsushige, 1000020828305, Kikuchi, Hiroshi, 1000060374443, Osawa, Takahiro, 1000080507591, Maruyama, Satoru, 1000090250422, Shinohara, Nobuo, 1000010762536, Matsumoto, Ryuji, 1000010399842, Abe, Takashige, Takada, Norikata, Minami, Keita, 1000070301900, Harabayashi, Toru, Nagamori, Satoshi, Hatanaka, Kanako C., Yamashiro, Katsushige, 1000020828305, Kikuchi, Hiroshi, 1000060374443, Osawa, Takahiro, 1000080507591, Maruyama, Satoru, 1000090250422, and Shinohara, Nobuo

Abstract

Objectives: This study investigated the relapse pattern and oncologic outcomes after laparoscopic nephroureterectomy with template-based lymph node dissection (LND) in patients with clinically node-negative (cN0) upper urinary tract urothelial carcinoma. The frequency of lymph node metastasis, including micrometastases, was also evaluated. Methods and materials: A total of 105 patients with cTa-3N0M0 upper urinary tract urothelial carcinoma were analyzed, all of whom underwent regional LND during laparoscopic nephroureterectomy. Of those patients, 96 (91%) underwent complete LND in accordance with an anatomical template-based rule. We collected patient characteristics, pathological data, and follow-up data from medical charts. Micrometastases were assessed by pan-cytokeratin immunohistochemistry. Nonurothelial recurrence-free survival and cancer-specific survival were estimated using the Kaplan-Meier method. Results: The median number of lymph nodes removed was 12 (range, 1-59). Lymph node metastasis was identified by routine pathological examination in 7 (7/105, 6.7%) patients. Pan-cytokeratin immunohistochemistry revealed micrometastases in 5 additional patients (pNmicro +: 5/105, 4.8%). Nonurothelial disease recurrence was observed in 21 (20%) patients at a median of 10 months (range: 1- 33) after surgery. Distant metastasis was dominant (15/105, 14.3%), followed by locoregional recurrence (5/105, 4.8%) and both (1/105, 0.95%). The 5-year nonurothelial recurrence-free survival rates were 84.8% for pN0, 53.3% for pNmicro+, and 19.1% for pN+ (3-sample log-rank test, P < 0.0001). The 5-year cancer-specific survival rates were 95.0% for pN0, 53.3% for pNmicro+, and 23.8% for pN+ (P < 0.0001). Conclusions: Our observation showed that template-based LND could contribute to precise disease staging and better local disease control probably by eliminating nodal disease, compared with previous studies. The survival impact and ideal management of pNmicro+ disease shou

Published
2020

153. Oncological outcomes of a multicenter cohort treated with axitinib for metastatic renal cell carcinoma

Author

Osawa, Takahiro, Kojima, Takahiro, Hara, Tomohiko, Sugimoto, Mikio, Eto, Masatoshi, Takeuchi, Ario, Minami, Keita, Nakai, Yasutomo, Ueda, Kosuke, Ozawa, Michinobu, Uemura, Motohide, Miyauchi, Yasuyuki, Ohba, Kojiro, Suzuki, Toshiro, Anai, Satoshi, Shindo, Tetsuya, Kusakabe, Naohisa, Tamura, Keita, Komiyama, Motokiyo, Goto, Takayuki, Yokomizo, Akira, Kohei, Naoki, Kashiwagi, Akira, Murakami, Masaya, Sazuka, Tomokazu, YASUMOTO, Hiroaki, Iwamoto, Hideto, Mitsuzuka, Koji, Morooka, Daichi, Shimazui, Toru, Yamamoto, Yoshiaki, Ikeshiro, Suguru, Nakagomi, Hiroshi, Morita, Ken, Tomida, Ryotaro, Mochizuki , Tango, Inoue , Takamitsu, Kitamura, Hiroshi, Yamada, Shuhei, Ito, Yoichi M., Murai, Sachiyo, Nishiyama Hiroyuki, Shinohara , Nobuo, Osawa, Takahiro, Kojima, Takahiro, Hara, Tomohiko, Sugimoto, Mikio, Eto, Masatoshi, Takeuchi, Ario, Minami, Keita, Nakai, Yasutomo, Ueda, Kosuke, Ozawa, Michinobu, Uemura, Motohide, Miyauchi, Yasuyuki, Ohba, Kojiro, Suzuki, Toshiro, Anai, Satoshi, Shindo, Tetsuya, Kusakabe, Naohisa, Tamura, Keita, Komiyama, Motokiyo, Goto, Takayuki, Yokomizo, Akira, Kohei, Naoki, Kashiwagi, Akira, Murakami, Masaya, Sazuka, Tomokazu, YASUMOTO, Hiroaki, Iwamoto, Hideto, Mitsuzuka, Koji, Morooka, Daichi, Shimazui, Toru, Yamamoto, Yoshiaki, Ikeshiro, Suguru, Nakagomi, Hiroshi, Morita, Ken, Tomida, Ryotaro, Mochizuki , Tango, Inoue , Takamitsu, Kitamura, Hiroshi, Yamada, Shuhei, Ito, Yoichi M., Murai, Sachiyo, Nishiyama Hiroyuki, and Shinohara , Nobuo

Published
2020

154. Prognostic impact of local radiotherapy on metastatic urothelial carcinoma patients receiving systemic chemotherapy

Author

1000010399842, Abe, Takashige, Minami, Keita, 1000070301900, Harabayashi, Toru, 1000060374287, Sazawa, Ataru, Chiba, Hiroki, Kikuchi, Hiroshi, Miyata, Haruka, Frumido, Jun, 1000010762536, Matsumoto, Ryuji, 1000060374443, Osawa, Takahiro, Junji, Ishizaki, Tango, Mochizuki, Satoshi, Chiba, Tomoshige, Akino, 1000090261304, Masashi, Murakumo, 1000040581111, Naoto, Miyajima, 1000050374442, Kunihiko, Tsuchiya, 1000080507591, Satoru, Maruyama, Murai, Sachiyo, 1000090250422, Shinohara, Nobuo, 1000010399842, Abe, Takashige, Minami, Keita, 1000070301900, Harabayashi, Toru, 1000060374287, Sazawa, Ataru, Chiba, Hiroki, Kikuchi, Hiroshi, Miyata, Haruka, Frumido, Jun, 1000010762536, Matsumoto, Ryuji, 1000060374443, Osawa, Takahiro, Junji, Ishizaki, Tango, Mochizuki, Satoshi, Chiba, Tomoshige, Akino, 1000090261304, Masashi, Murakumo, 1000040581111, Naoto, Miyajima, 1000050374442, Kunihiko, Tsuchiya, 1000080507591, Satoru, Maruyama, Murai, Sachiyo, 1000090250422, and Shinohara, Nobuo

Abstract

Objective To clarify the prognostic impact of local radiotherapy on metastatic urothelial carcinoma patients treated by systemic chemotherapy. Methods Of the 228 metastatic urothelial carcinoma patients treated with systemic chemotherapy, 97 received radiotherapy mainly to metastatic sites. In patients for whom the purpose of radiotherapy was not specified, more than 50 Gy irradiation was considered to be for disease consolidation for survival analysis, while less than 50 Gy was categorized as palliation. According to the Kaplan-Meier method, we analysed overall survival from the initiation of treatment for metastatic urothelial carcinoma until death or the last follow-up, using the log-rank test to assess the significance of differences. The Cox model was applied for prognostic factor analysis. Results Overall, there was no significant difference in survival between patients with and those without radiotherapy (P = 0.1532). When analysing the patients undergoing consolidative radiotherapy separately, these 25 patients showed significantly longer survival than the 72 patients with palliative radiotherapy (P = 0.0047), with a 3-year overall survival of 43.3%. Of the present cohort, 22 underwent metastasectomy for disease consolidation, and there was no overlapping case between the metastasectomy cohort and cohort receiving consolidative radiotherapy. After controlling for four independent prognostic factors (sex, performance status, haemoglobin level and number of organs with metastasis) in our previous study, radiotherapy for disease consolidation showed a marginal value (hazard ratio = 0.666, P = 0.0966), while metastasectomy remained significant (hazard ratio = 0.358, P = 0.0006). Conclusions In the selected patients, long-term disease control could be achieved after consolidative radiotherapy for metastatic urothelial carcinoma disease. Our observations suggest that local ablative therapy (surgery or radiotherapy) could facilitate long-term disease control. Howev

Published
2020

155. Development and validation of a porcine organ model for training in essential laparoscopic surgical skills

Author

Higuchi, Madoka, 1000010399842, Abe, Takashige, 1000090443936, Hotta, Kiyohiko, Morita, Ken, Miyata, Haruka, Furumido, Jun, Iwahara, Naoya, 1000040802799, Kon, Masafumi, 1000060374443, Osawa, Takahiro, 1000010762536, Matsumoto, Ryuji, 1000020828305, Kikuchi, Hiroshi, 1000040374350, Kurashima, Yo, Murai, Sachiyo, Aydin, Abdullatif, Raison, Nicholas, Ahmed, Kamran, Khan, Muhammad Shamim, Dasgupta, Prokar, 1000090250422, Shinohara, Nobuo, Higuchi, Madoka, 1000010399842, Abe, Takashige, 1000090443936, Hotta, Kiyohiko, Morita, Ken, Miyata, Haruka, Furumido, Jun, Iwahara, Naoya, 1000040802799, Kon, Masafumi, 1000060374443, Osawa, Takahiro, 1000010762536, Matsumoto, Ryuji, 1000020828305, Kikuchi, Hiroshi, 1000040374350, Kurashima, Yo, Murai, Sachiyo, Aydin, Abdullatif, Raison, Nicholas, Ahmed, Kamran, Khan, Muhammad Shamim, Dasgupta, Prokar, 1000090250422, and Shinohara, Nobuo

Abstract

Objectives To develop a wet laboratory training model for learning core laparoscopic surgical skills and evaluating learners' competency level outside the operating room. Methods Participants completed three tasks (task 1: tissue dissection around the aorta; task 2: tissue dissection and division of the renal artery; task 3: renal parenchymal closure). Each performance was video recorded and subsequently evaluated by two experts, according to the Global Operative Assessment of Laparoscopic Skills and task-specific metrics that we developed (Assessment Sheet of Laparoscopic Skills in Wet Lab score). Mean scores were used for analyses. The subjective mental workload was also assessed (NASA Task Load Index). Results The 54 participants included 32 urologists, eight young trainees and 14 medical students. A total of 13 participants were categorized as experts (>= 50 laparoscopic surgeries), eight as intermediates (10-49) and 33 as novices (0-9). There were significant differences in the Global Operative Assessment of Laparoscopic Skills and Assessment Sheet of Laparoscopic Skills in Wet Lab scores among the three groups in all three tasks. Higher NASA Task Load Index scores were observed in novices, and there were significant differences in tasks 1 (Kruskal-Wallis test,P = 0.0004) and 2 (P = 0.0002), and marginal differences in task 3 (P = 0.0745) among the three groups. Conclusions Our training model has good construct validity, and differences in the NASA Task Load Index score reflect previous laparoscopic surgical experiences. Our findings show the ability to assess both laparoscopic surgical skills and mental workloads, which could help educators comprehend trainees' level outside the operating room. Given the decreasing opportunity to carry out pure laparoscopic surgeries because of the dissemination of robotic surgery, especially in urology, our model can offer practical training opportunities.

Published
2020

156. Oncological outcomes of a multicenter cohort treated with axitinib for metastatic renal cell carcinoma

Author

1000060374443, Osawa, Takahiro, 1000040626892, Kojima, Takahiro, Hara, Tomohiko, 1000010243768, Sugimoto, Mikio, 1000090315078, Eto, Masatoshi, 1000030586756, Takeuchi, Ario, Minami, Keita, Nakai, Yasutomo, Ueda, Kosuke, Ozawa, Michinobu, 1000040631015, Uemura, Motohide, Miyauchi, Yasuyuki, 1000020593825, Ohba, Kojiro, Suzuki, Toshiro, 1000070526699, Anai, Satoshi, 1000080749292, Shindo, Tetsuya, Kusakabe, Naohisa, Tamura, Keita, Komiyama, Motokiyo, 1000090806605, Goto, Takayuki, 1000060346781, Yokomizo, Akira, Kohei, Naoki, Kashiwagi, Akira, Murakami, Masaya, 1000090623679, Sazuka, Tomokazu, 1000020314750, Yasumoto, Hiroaki, 1000080621010, Iwamoto, Hideto, 1000080568171, Mitsuzuka, Koji, Morooka, Daichi, 1000080235613, Shimazui, Toru, Yamamoto, Yoshiaki, Ikeshiro, Suguru, Nakagomi, Hiroshi, Morita, Ken, Tomida, Ryotaro, Mochizuki, Tango, 1000060375243, Inoue, Takamitsu, Kitamura, Hiroshi, Yamada, Shuhei, Ito, Yoichi M., Murai, Sachiyo, 1000020324642, Nishiyama, Hiroyuki, 1000090250422, Shinohara, Nobuo, 1000060374443, Osawa, Takahiro, 1000040626892, Kojima, Takahiro, Hara, Tomohiko, 1000010243768, Sugimoto, Mikio, 1000090315078, Eto, Masatoshi, 1000030586756, Takeuchi, Ario, Minami, Keita, Nakai, Yasutomo, Ueda, Kosuke, Ozawa, Michinobu, 1000040631015, Uemura, Motohide, Miyauchi, Yasuyuki, 1000020593825, Ohba, Kojiro, Suzuki, Toshiro, 1000070526699, Anai, Satoshi, 1000080749292, Shindo, Tetsuya, Kusakabe, Naohisa, Tamura, Keita, Komiyama, Motokiyo, 1000090806605, Goto, Takayuki, 1000060346781, Yokomizo, Akira, Kohei, Naoki, Kashiwagi, Akira, Murakami, Masaya, 1000090623679, Sazuka, Tomokazu, 1000020314750, Yasumoto, Hiroaki, 1000080621010, Iwamoto, Hideto, 1000080568171, Mitsuzuka, Koji, Morooka, Daichi, 1000080235613, Shimazui, Toru, Yamamoto, Yoshiaki, Ikeshiro, Suguru, Nakagomi, Hiroshi, Morita, Ken, Tomida, Ryotaro, Mochizuki, Tango, 1000060375243, Inoue, Takamitsu, Kitamura, Hiroshi, Yamada, Shuhei, Ito, Yoichi M., Murai, Sachiyo, 1000020324642, Nishiyama, Hiroyuki, 1000090250422, and Shinohara, Nobuo

Abstract

The present study aimed to evaluate the efficacy of the real-world use of axitinib and to develop a prognostic model for stratifying patients who could derive long-term benefit from axitinib. This was a retrospective, descriptive study evaluating the efficacy of axitinib in patients with metastatic renal cell carcinoma that had been treated with 1 or 2 systemic antiangiogenic therapy regimens at 1 of 36 hospitals belonging to the Japan Urologic Oncology Group between January 2012 and February 2019. The primary outcome was overall survival (OS). Using a split-sample method, candidate variables that exhibited significant relationships with OS were chosen to create a model. The new model was validated using the rest of the cohort. In total, 485 patients were enrolled. The median OS was 34 months in the entire study population, whereas it was not reached, 27 months, and 14 months in the favorable, intermediate, and poor risk groups, respectively, according to the new risk classification model. The following 4 variables were included in the final risk model: the disease stage at diagnosis, number of metastatic sites at the start of axitinib therapy, serum albumin level, and neutrophil : lymphocyte ratio. The adjusted area under the curve values of the new model at 12, 36, and 60 months were 0.77, 0.82, and 0.82, respectively. The efficacy of axitinib in routine practice is comparable or even superior to that reported previously. The patients in the new model's favorable risk group might derive a long-term survival benefit from axitinib treatment.

Published
2020

157. The updated outcomes of bladder-preserving trimodal therapy using a real-time tumor-tracking radiotherapy system for patients with muscle-invasive bladder cancer

Author

Miyata, Haruka, 1000060374443, Osawa, Takahiro, 1000010399842, Abe, Takashige, 1000020828305, Kikuchi, Hiroshi, 1000010762536, Matsumoto, Ryuji, 1000080507591, Maruyama, Satoru, 1000080463743, Nishioka, Kentaro, 1000050463724, Shimizu, Shinichi, 1000060400678, Hashimoto, Takayuki, 1000020187537, Shirato, Hiroki, 1000090250422, Shinohara, Nobuo, Miyata, Haruka, 1000060374443, Osawa, Takahiro, 1000010399842, Abe, Takashige, 1000020828305, Kikuchi, Hiroshi, 1000010762536, Matsumoto, Ryuji, 1000080507591, Maruyama, Satoru, 1000080463743, Nishioka, Kentaro, 1000050463724, Shimizu, Shinichi, 1000060400678, Hashimoto, Takayuki, 1000020187537, Shirato, Hiroki, 1000090250422, and Shinohara, Nobuo

Abstract

Objective: Bladder-preserving trimodal therapy is recognized as a promising alternative treatment for muscle-invasive bladder cancer. We report the updated outcomes of muscle-invasive bladder cancer patients that were treated using our treatment protocol, which involves radiotherapy delivered with a real-time tumor-tracking radiotherapy system. Methods: Thirty-eight patients who were diagnosed with T2-T4N0M0 bladder cancer between 1998 and 2016 and had clinically inoperable disease or refused to undergo surgery were enrolled. The treatment protocol included maximal transurethral resection followed by whole-bladder radiotherapy (40 Gy). Concurrent nedaplatin-based chemotherapy was administered to patients with adequate renal function. At the time of the first evaluation (via transurethral resection of the tumor bed), fiducial markers were endoscopically inserted into the bladder wall around the tumor. A boost of 25 Gy was administered using the real-time tumor-tracking radiotherapy system. The second evaluation (via transurethral resection of the tumor bed) was performed 6 months after the start of treatment. The Kaplan-Meier method and Cox hazards analysis were used to analyze overall survival and cancer-specific survival. Results: The median duration of the follow-up period was 28 months (range: 3-161 months). The 5- and 10-year overall survival rates were 54.9 and 41.2%, respectively. Twenty-five (65.8%) and twenty (74.1%) patients had achieved complete responses to chemoradiation at the first and second evaluations, respectively. In univariate and multivariate analyses, performance status was found to be significantly associated with overall survival [P = 0.03, hazard ratio: 3.48, 95% confidence interval: 1.15-10.6] and cancer-specific survival [P = 0.02, hazard ratio: 4.57, 95% confidence interval: 1.32-16.9], and sex was shown to be significantly associated with cancer-specific survival [P = 0.03, hazard ratio: 3.07, 95% confidence interval: 1.09-8.30]. Conclus

Published
2020

158. Validity assessment of the laparoscopic radical nephrectomy module of the LapVision virtual reality simulator

Author

Miyata, Haruka, 1000010399842, Abe, Takashige, 1000090443936, Hotta, Kiyohiko, Higuchi, Madoka, 1000060374443, Osawa, Takahiro, 1000010762536, Matsumoto, Ryuji, 1000020828305, Kikuchi, Hiroshi, 1000040374350, Kurashima, Yo, Murai, Sachiyo, 1000090250422, Shinohara, Nobuo, Miyata, Haruka, 1000010399842, Abe, Takashige, 1000090443936, Hotta, Kiyohiko, Higuchi, Madoka, 1000060374443, Osawa, Takahiro, 1000010762536, Matsumoto, Ryuji, 1000020828305, Kikuchi, Hiroshi, 1000040374350, Kurashima, Yo, Murai, Sachiyo, 1000090250422, and Shinohara, Nobuo

Abstract

Background: Virtual reality simulators allow trainees to perform repeated practice and provide objective dexterity metrics regarding their performance, which means that virtual reality-based surgical training is becoming a vital part of initial learning of basic laparoscopic surgical skills. However, its educational role in learning advanced procedures remains undetermined. We evaluated the validity of the laparoscopic radical nephrectomy module of the LapVision virtual reality simulator. Methods: Urologists, medical students, and a junior resident voluntarily participated in the present study, and they performed training with a laparoscopic left radical nephrectomy module. For construct validation, dexterity metrics calculated in the simulator and the mean score of Global Operative Assessment of Laparoscopic Skills evaluated by 2 experts' video review were compared according to the certification of Japanese Endoscopic Surgical Skill Qualification or previous surgical experience. Results: Ten experts (>= 50 laparoscopic surgeries), 9 intermediates (11-49), and 14 novices (0-10) voluntarily participated in the present study. Regarding the construct validity, there was a significant difference in the total number of errors, blood loss, and Global Operative Assessment of Laparoscopic Skills score among the groups for both the Endoscopic Surgical Skill Qualification status and previous surgical experience. Conclusion: The present study demonstrated good construct validity for the LapVision nephrectomy module. Furthermore, global skill assessment was possible by experts' reviews, which indicates the usefulness of the virtual reality procedural module as a skill assessment tool. Virtual reality-based procedural simulation has marked potential to become a vital part of integrated laparoscopic training programs. (C) 2019 The Authors. Published by Elsevier Inc.

Published
2020

159. Prognostic impact of local radiotherapy on metastatic urothelial carcinoma patients receiving systemic chemotherapy

Author

Abe, Takashige, Minami, Keita, Harabayashi, Toru, Sazawa, Ataru, Chiba, Hiroki, Kikuchi, Hiroshi, Miyata, Haruka, Frumido, Jun, Matsumoto, Ryuji, Osawa, Takahiro, Junji, Ishizaki, Tango, Mochizuki, Satoshi, Chiba, Tomoshige, Akino, Masashi, Murakumo, Naoto, Miyajima, Kunihiko, Tsuchiya, Satoru, Maruyama, Murai, Sachiyo, Shinohara, Nobuo, Abe, Takashige, Minami, Keita, Harabayashi, Toru, Sazawa, Ataru, Chiba, Hiroki, Kikuchi, Hiroshi, Miyata, Haruka, Frumido, Jun, Matsumoto, Ryuji, Osawa, Takahiro, Junji, Ishizaki, Tango, Mochizuki, Satoshi, Chiba, Tomoshige, Akino, Masashi, Murakumo, Naoto, Miyajima, Kunihiko, Tsuchiya, Satoru, Maruyama, Murai, Sachiyo, and Shinohara, Nobuo

Abstract

Objective To clarify the prognostic impact of local radiotherapy on metastatic urothelial carcinoma patients treated by systemic chemotherapy. Methods Of the 228 metastatic urothelial carcinoma patients treated with systemic chemotherapy, 97 received radiotherapy mainly to metastatic sites. In patients for whom the purpose of radiotherapy was not specified, more than 50 Gy irradiation was considered to be for disease consolidation for survival analysis, while less than 50 Gy was categorized as palliation. According to the Kaplan-Meier method, we analysed overall survival from the initiation of treatment for metastatic urothelial carcinoma until death or the last follow-up, using the log-rank test to assess the significance of differences. The Cox model was applied for prognostic factor analysis. Results Overall, there was no significant difference in survival between patients with and those without radiotherapy (P = 0.1532). When analysing the patients undergoing consolidative radiotherapy separately, these 25 patients showed significantly longer survival than the 72 patients with palliative radiotherapy (P = 0.0047), with a 3-year overall survival of 43.3%. Of the present cohort, 22 underwent metastasectomy for disease consolidation, and there was no overlapping case between the metastasectomy cohort and cohort receiving consolidative radiotherapy. After controlling for four independent prognostic factors (sex, performance status, haemoglobin level and number of organs with metastasis) in our previous study, radiotherapy for disease consolidation showed a marginal value (hazard ratio = 0.666, P = 0.0966), while metastasectomy remained significant (hazard ratio = 0.358, P = 0.0006). Conclusions In the selected patients, long-term disease control could be achieved after consolidative radiotherapy for metastatic urothelial carcinoma disease. Our observations suggest that local ablative therapy (surgery or radiotherapy) could facilitate long-term disease control. Howev

Published
2020

160. Oncologic outcomes of laparoscopic radical nephroureterectomy in conjunction with template-based lymph node dissection : An extended follow-up study

Author

Matsumoto, Ryuji, Abe, Takashige, Takada, Norikata, Minami, Keita, Harabayashi, Toru, Nagamori, Satoshi, Hatanaka, Kanako C., Yamashiro, Katsushige, Kikuchi, Hiroshi, Osawa, Takahiro, Maruyama, Satoru, Shinohara, Nobuo, Matsumoto, Ryuji, Abe, Takashige, Takada, Norikata, Minami, Keita, Harabayashi, Toru, Nagamori, Satoshi, Hatanaka, Kanako C., Yamashiro, Katsushige, Kikuchi, Hiroshi, Osawa, Takahiro, Maruyama, Satoru, and Shinohara, Nobuo

Abstract

Objectives: This study investigated the relapse pattern and oncologic outcomes after laparoscopic nephroureterectomy with template-based lymph node dissection (LND) in patients with clinically node-negative (cN0) upper urinary tract urothelial carcinoma. The frequency of lymph node metastasis, including micrometastases, was also evaluated. Methods and materials: A total of 105 patients with cTa-3N0M0 upper urinary tract urothelial carcinoma were analyzed, all of whom underwent regional LND during laparoscopic nephroureterectomy. Of those patients, 96 (91%) underwent complete LND in accordance with an anatomical template-based rule. We collected patient characteristics, pathological data, and follow-up data from medical charts. Micrometastases were assessed by pan-cytokeratin immunohistochemistry. Nonurothelial recurrence-free survival and cancer-specific survival were estimated using the Kaplan-Meier method. Results: The median number of lymph nodes removed was 12 (range, 1-59). Lymph node metastasis was identified by routine pathological examination in 7 (7/105, 6.7%) patients. Pan-cytokeratin immunohistochemistry revealed micrometastases in 5 additional patients (pNmicro +: 5/105, 4.8%). Nonurothelial disease recurrence was observed in 21 (20%) patients at a median of 10 months (range: 1- 33) after surgery. Distant metastasis was dominant (15/105, 14.3%), followed by locoregional recurrence (5/105, 4.8%) and both (1/105, 0.95%). The 5-year nonurothelial recurrence-free survival rates were 84.8% for pN0, 53.3% for pNmicro+, and 19.1% for pN+ (3-sample log-rank test, P < 0.0001). The 5-year cancer-specific survival rates were 95.0% for pN0, 53.3% for pNmicro+, and 23.8% for pN+ (P < 0.0001). Conclusions: Our observation showed that template-based LND could contribute to precise disease staging and better local disease control probably by eliminating nodal disease, compared with previous studies. The survival impact and ideal management of pNmicro+ disease should be

Published
2020

161. Treatment Outcome of Axitinib for Metastatic Renal-Cell Carcinoma Patients

Author

Kusakabe, Naohisa, Osawa, Takahiro, Miyata, Haruka, Kikuchi, Hiroshi, Matsumoto, Ryuji, Maruyama, Satoru, Abe, Takashige, and Shinohara, Nobuo

Subjects
Targeted therapy, Axitinib, 494.9, Renal-cell carcinoma, Metastasis
Abstract

Axitinib was approved for use in Japan as a salvage therapy for patients with metastatic renal cell carcinoma (RCC) in 2012. We retrospectively evaluated the cases of 32 RCC patients that were treated with Axitinib as a 2nd- or further-line therapy between November 2012 and March 2017. Overall survival (OS), progression-free survival (PFS), and adverse events were assessed. The median OS and PFS from the initiation of Axitinib were 29 and 11 months, respectively. Nineteen patients received Axitinib as a 2nd-line treatment, in whom the median OS and median PFS were 22 and 10 months, respectively, while the median OS and PFS were 29 and 15.5 months, respectively, amongthe 13 patients who received Axitinib as a 3rd- or further-line treatment, which suggested that Axitinib is effective in the 3rd-line and further-line settings. A Cox multivariate model revealed that bone metastasis was a significant adverse factor for OS. Common grade 3 or higher adverse events included hypertension (28%), diarrhea (7%), and proteinuria (7%). Although the present study demonstrated the efficacy and safety of salvage Axitinib treatment in patients who had recurrent disease after the initial systemic therapy, further large-scale studies should be warranted to make clear its clinical effectiveness in these patients.

Published
2018

162. Landscape of genomic alterations of circulating tumor DNA in advanced genitourinary cancer patients: SCRUM-Japan MONSTAR SCREEN Project.

Author

Matsubara, Nobuaki, primary, Kato, Taigo, additional, Fujisawa, Takao, additional, Shiota, Masaki, additional, Eto, Masatoshi, additional, Osawa, Takahiro, additional, Abe, Takashige, additional, Shinohara, Nobuo, additional, Yasumizu, Yota, additional, Tanaka, Nobuyuki, additional, Oya, Mototsugu, additional, Nishimoto, Koshiro, additional, Horasawa, Satoshi, additional, Kuramoto, Naomi, additional, Nakamura, Yoshiaki, additional, Taniguchi, Hiroya, additional, Yoshino, Takayuki, additional, and Nonomura, Norio, additional

Published
2021
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163. Impact of the Strong Downwelling (Upwelling) on Small Pelagic Fish Production during the 2016 (2019) Negative (Positive) Indian Ocean Dipole Events in the Eastern Indian Ocean off Java

Author

Lumban-Gaol, Jonson, primary, Siswanto, Eko, additional, Mahapatra, Kedarnath, additional, Natih, Nyoman Metta Nyanakumara, additional, Nurjaya, I Wayan, additional, Hartanto, Mochamad Tri, additional, Maulana, Erwin, additional, Adrianto, Luky, additional, Rachman, Herlambang Aulia, additional, Osawa, Takahiro, additional, Rahman, Berri Miraz Kholipah, additional, and Permana, Arik, additional

Published
2021
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167. The Impact of Daily Urinary Volume Variations and Prostate Volume on Prostate Position During Radiotherapy

Author

Nishioka, Kentaro, primary, Hashimoto, Takayuki, additional, Abe, Takashige, additional, Osawa, Takahiro, additional, Matsumoto, Ryuji, additional, Yokota, Isao, additional, Katoh, Norio, additional, Kinoshita, Rumiko, additional, Yasuda, Koichi, additional, Yakabe, Toshiaki, additional, Yoshimura, Takaaki, additional, Takao, Seishin, additional, Shinohara, Nobuo, additional, Aoyama, Hidefumi, additional, and Shimizu, Shinichi, additional

Published
2020
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168. Oncologic outcomes of laparoscopic radical nephroureterectomy in conjunction with template-based lymph node dissection: An extended follow-up study

Author

Matsumoto, Ryuji, primary, Abe, Takashige, additional, Takada, Norikata, additional, Minami, Keita, additional, Harabayashi, Toru, additional, Nagamori, Satoshi, additional, Hatanaka, Kanako C., additional, Yamashiro, Katsushige, additional, Kikuchi, Hiroshi, additional, Osawa, Takahiro, additional, Maruyama, Satoru, additional, and Shinohara, Nobuo, additional

Published
2020
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173. List of contributors

Author

Akhir, Mohd Fadzil, Alfante, Rey Mark, Amedo-Repollo, Charina Lyn, Arini, Dwi Puspa, Atikah Alihan, Nur Surayatul, Balakrishnan Nair, T.M., Bauzon, Ma. Divina Angela, Blanco, Ariel, Bringas, Dennis, Flores, Paul Caesar M., Hamden, Mohammad Hanif, Han, Guoqi, Hwang, Do-Hyun, Ichikawa, Kaoru, Idris, Nurul Hazrina, Ito, Masashi, Li, Xiaohui, Lumban-Gaol, J., Luu, Quang-Hung, M., Nagaraja Kumar, Mahendra, R.S., Mansor, Ku Nor Afiza Asnida Ku, Md Din, Ami Hassan, Mohanty, P.C., Morimoto, Akihiko, Nayak, R.K., Nimit, Kumar, Osawa, Takahiro, Pasaje, Nikki Alen, Rediang, Abegail, Reyes, Rosalie B., Rudiastuti, A.W., Shirozu, Hajime, Sinurat, M.E., Siringan, Fernando P., Srinivasa Kumar, T., Sudheer, J., Swetha, N., Takikawa, Tetsutaro, Tamura, Hiroshi, Tkalich, Pavel, Vignudelli, Stefano, Wang, XiFeng, Wei, Dongni, Wijaya, Dudy Darmawan, Yang, Jingsong, Yoon, Hong-Joo, and Zainol, Zuraini

Published
2023
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174. Validation study of the Japanese version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire‐Testicular Cancer 26 for patients with testicular cancer

Author

Yamashita, Shinichi, primary, Suzukamo, Yoshimi, additional, Kakimoto, Kenichi, additional, Uemura, Motohide, additional, Kishida, Takeshi, additional, Kawai, Koji, additional, Nakamura, Terukazu, additional, Goto, Takayuki, additional, Osawa, Takahiro, additional, Yamada, Shigeyuki, additional, Nishimura, Kazuo, additional, Nonomura, Norio, additional, Nishiyama, Hiroyuki, additional, Shiraishi, Takumi, additional, Ukimura, Osamu, additional, Ogawa, Osamu, additional, Shinohara, Nobuo, additional, Ito, Akihiro, additional, and Arai, Yoichi, additional

Published
2020
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175. The Strong Downwelling (Upwelling) Impact on Small Pelagic Fish Production During the 2016 (2019) Negative (Positive) Indian Ocean Dipole Events in the Eastern Indian Ocean off Java

Author

Lumban-Gaol, Jonson, primary, Siswanto, Eko, additional, Natih, Nyoman Metta N., additional, Nurjaya, I Wayan, additional, Hartanto, Mochammad Tri, additional, Maulana, Erwin, additional, Adrianto, Lucky, additional, Mahapatra, Kedarnath, additional, Rachman, Herlambang Aulia, additional, Osawa, Takahiro, additional, and Permana, Arik, additional

Published
2020
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176. Impact of the MyProstateScore (MPS) Test on the Clinical Decision to Undergo Prostate Biopsy: Results From a Contemporary Academic Practice

Author

Lebastchi, Amir H., primary, Russell, Christopher M., additional, Niknafs, Yashar S., additional, Eyrich, Nicholas W., additional, Chopra, Zoey, additional, Botbyl, Rachel, additional, Kabeer, Rana, additional, Osawa, Takahiro, additional, Siddiqui, Javed, additional, Siddiqui, Rabia, additional, Davenport, Matthew S., additional, Mehra, Rohit, additional, Tomlins, Scott A., additional, Kunju, Lakshimi P., additional, Chinnaiyan, Arul M., additional, Wei, John T., additional, Tosoian, Jeffrey J., additional, and Morgan, Todd M., additional

Published
2020
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177. Health-related quality of life in Japanese low-risk prostate cancer patients choosing active surveillance: 3-year follow-up from PRIAS-JAPAN

Author

Hirama, Hiromi, primary, Sugimoto, Mikio, additional, Miyatake, Nobuyuki, additional, Kato, Takuma, additional, Venderbos, Lionne D. F., additional, Remmers, Sebastiaan, additional, Shiga, Kenichiro, additional, Yokomizo, Akira, additional, Mitsuzuka, Koji, additional, Matsumoto, Ryuji, additional, Osawa, Takahiro, additional, Abe, Takashige, additional, Sasaki, Hiroshi, additional, Egawa, Shin, additional, Ninomiya, Iku, additional, Hashine, Katsuyoshi, additional, Roobol, Monique J., additional, and Kakehi, Yoshiyuki, additional

Published
2020
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178. Correction to: Motion analysis for better understanding of psychomotor skills in laparoscopy: objective assessment-based simulation training using animal organs

Author

Ebina, Koki, primary, Abe, Takashige, additional, Higuchi, Madoka, additional, Furumido, Jun, additional, Iwahara, Naoya, additional, Kon, Masafumi, additional, Hotta, Kiyohiko, additional, Komizunai, Shunsuke, additional, Kurashima, Yo, additional, Kikuchi, Hiroshi, additional, Matsumoto, Ryuji, additional, Osawa, Takahiro, additional, Murai, Sachiyo, additional, Tsujita, Teppei, additional, Sase, Kazuya, additional, Chen, Xiaoshuai, additional, Konno, Atsushi, additional, and Shinohara, Nobuo, additional

Published
2020
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179. Motion analysis for better understanding of psychomotor skills in laparoscopy: objective assessment-based simulation training using animal organs

Author

Ebina, Koki, primary, Abe, Takashige, additional, Higuchi, Madoka, additional, Furumido, Jun, additional, Iwahara, Naoya, additional, Kon, Masafumi, additional, Hotta, Kiyohiko, additional, Komizunai, Shunsuke, additional, Kurashima, Yo, additional, Kikuchi, Hiroshi, additional, Matsumoto, Ryuji, additional, Osawa, Takahiro, additional, Murai, Sachiyo, additional, Tsujita, Teppei, additional, Sase, Kazuya, additional, Chen, Xiaoshuai, additional, Konno, Atsushi, additional, and Shinohara, Nobuo, additional

Published
2020
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180. Cabozantinib in advanced renal cell carcinoma: A phase II, open‐label, single‐arm study of Japanese patients

Author

Tomita, Yoshihiko, primary, Tatsugami, Katsunori, additional, Nakaigawa, Noboru, additional, Osawa, Takahiro, additional, Oya, Mototsugu, additional, Kanayama, Hiroomi, additional, Nakayama Kondoh, Chihiro, additional, Sassa, Naoto, additional, Nishimura, Kazuo, additional, Nozawa, Masahiro, additional, Masumori, Naoya, additional, Miyoshi, Yasuhide, additional, Kuroda, Shingo, additional, Tanaka, Shingo, additional, Kimura, Akiko, additional, and Tamada, Satoshi, additional

Published
2020
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181. Development and validation of a porcine organ model for training in essential laparoscopic surgical skills

Author

Higuchi, Madoka, primary, Abe, Takashige, additional, Hotta, Kiyohiko, additional, Morita, Ken, additional, Miyata, Haruka, additional, Furumido, Jun, additional, Iwahara, Naoya, additional, Kon, Masafumi, additional, Osawa, Takahiro, additional, Matsumoto, Ryuji, additional, Kikuchi, Hiroshi, additional, Kurashima, Yo, additional, Murai, Sachiyo, additional, Aydin, Abdullatif, additional, Raison, Nicholas, additional, Ahmed, Kamran, additional, Khan, Muhammad Shamim, additional, Dasgupta, Prokar, additional, and Shinohara, Nobuo, additional

Published
2020
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182. Chemotherapy-Induced IL8 Upregulates MDR1/ABCB1 in Tumor Blood Vessels and Results in Unfavorable Outcome

Author

Kikuchi, Hiroshi, primary, Maishi, Nako, additional, Annan, Dorcas A., additional, Alam, Mohammad Towfik, additional, Dawood, Randa Ibrahim Hassan, additional, Sato, Masumi, additional, Morimoto, Masahiro, additional, Takeda, Ryo, additional, Ishizuka, Keita, additional, Matsumoto, Ryuji, additional, Akino, Tomoshige, additional, Tsuchiya, Kunihiko, additional, Abe, Takashige, additional, Osawa, Takahiro, additional, Miyajima, Naoto, additional, Maruyama, Satoru, additional, Harabayashi, Toru, additional, Azuma, Manabu, additional, Yamashiro, Katsushige, additional, Ameda, Kaname, additional, Kashiwagi, Akira, additional, Matsuno, Yoshihiro, additional, Hida, Yasuhiro, additional, Shinohara, Nobuo, additional, and Hida, Kyoko, additional

Published
2020
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183. A pooled analysis of the efficacy and safety of cabozantinib post immunotherapy in patients with advanced renal cell carcinoma.

Author

Oya, Mototsugu, primary, Tamada, Satoshi, additional, Tatsugami, Katsunori, additional, Nakaigawa, Noboru, additional, Osawa, Takahiro, additional, Kanayama, Hiro-Omi, additional, Kondoh, Chihiro, additional, Sassa, Naoto, additional, Nishimura, Kazuo, additional, Nozawa, Masahiro, additional, Masumori, Naoya, additional, Miyoshi, Yasuhide, additional, Kimura, Akiko, additional, Kuroda, Shingo, additional, Motzer, Robert J., additional, Choueiri, Toni K., additional, and Tomita, Yoshihiko, additional

Published
2020
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184. Erratum: Prognostic impact of local radiotherapy on metastatic urothelial carcinoma patients receiving systemic chemotherapy

Author

Abe, Takashige, primary, Minami, Keita, primary, Harabayashi, Toru, primary, Sazawa, Ataru, primary, Chiba, Hiroki, primary, Kikuchi, Hiroshi, primary, Miyata, Haruka, primary, Frumido, Jun, primary, Matsumoto, Ryuji, primary, Osawa, Takahiro, primary, Junji, Ishizaki, primary, Tango, Mochizuki, primary, Satoshi, Chiba, primary, Tomoshige, Akino, primary, Masashi, Murakumo, primary, Naoto, Miyajima, primary, Kunihiko, Tsuchiya, primary, Satoru, Maruyama, primary, Murai, Sachiyo, primary, and Shinohara, Nobuo, primary

Published
2020
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185. PD18-02 THE EFFECTIVENESS OF TEMPLATE-BASED REGIONAL LYMPH NODE DISSECTION IN REDUCING LOCOREGIONAL RECURRENCE IN PATIENTS WITH CLINICALLY NODE-NEGATIVE UPPER URINARY TRACT UROTHELIAL CARCINOMA

Author

Matsumoto*, Ryuji, primary, Abe, Takashige, additional, Takada, Noritaka, additional, Minami, Keita, additional, Harabayashi, Toru, additional, Maruyama, Satoru, additional, Kikuchi, Hiroshi, additional, Osawa, Takahiro, additional, and Shinohara, Nobuo, additional

Published
2020
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186. MP72-14 LATE RECURRENCE OF NON-MUSCLE-INVASIVE BLADDER CANCER AFTER A 5-YEAR CANCER-FREE PERIOD

Author

Hirata*, Yurie, primary, Osawa, Takahiro, additional, Higuchi, Madoka, additional, Hinotsu, Shiro, additional, Harabayashi, Toru, additional, Mochizuki, Tango, additional, Enami, Nobuyasu, additional, Nounaka, Osamu, additional, Shinno, Yuichiro, additional, Kikuchi, Hiroshi, additional, Matsumoto, Ryuji, additional, Abe, Takashige, additional, Murai, Sachiyo, additional, and Shinohara, Nobuo, additional

Published
2020
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187. PD50-04 URINARY EXTRACELLULAR VESICLE RNA BIOMARKERS FOR HIGH-RISK NON-MUSCLE INVASIVE BLADDER CANCER

Author

Minami*, Keita, primary, Osawa, Takahiro, additional, Murakami, Taku, additional, Harada, Hiroshi, additional, Harabayashi, Toru, additional, Takada, Norikata, additional, Kashiwagi, Akira, additional, Hirakawa, Kazushi, additional, Sato, Yasuyuki, additional, Matsumoto, Ryuji, additional, Kikuchi, Hiroshi, additional, Abe, Takashige, additional, Murai, Sachiyo, additional, and Shinohara, Nobuo, additional

Published
2020
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188. MP47-07 MOTION ANALYSIS TO PROMOTE UNDERSTANDING OF LAPAROSCOPIC SURGERY-DEXTERITY AND OBJECTIVE ASSESSMENT-BASED SIMULATION TRAINING

Author

Abe*, Takashige, primary, Ebina, Koki, additional, Higuchi, Madoka, additional, Furumido, Jun, additional, Iwahara, Naoya, additional, Kon, Masafumi, additional, Hotta, Kiyohiko, additional, Komizunai, Shunsuke, additional, Kurashima, Yo, additional, Kikuchi, Hiroshi, additional, Matsumoto, Ryuji, additional, Osawa, Takahiro, additional, Murai, Sachiyo, additional, Konno, Atsushi, additional, and Shinohara, Nobuo, additional

Published
2020
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189. Health-related quality of life in Japanese patients with bladder cancer according to a newly developed Japanese version of the Bladder Cancer Index.

Author

Osawa, Takahiro, primary, Wei, John, additional, Abe, Takashige, additional, Yamada, Shuhei, additional, Frumido, Jun, additional, Miyata, Haruka, additional, Kikuchi, Hiroshi, additional, Matsumoto, Ryuji, additional, Sato, Yasuyuki, additional, Hirakawa, Kazushi, additional, Sasaki, Yoshihiro, additional, Tanaka, Hiroshi, additional, Kashiwagi, Akira, additional, Morita, Ken, additional, Takada, Norikata, additional, Minami, Keita, additional, Harabayashi, Toru, additional, Murai, Sachiyo, additional, and Shinohara, Nobuo, additional

Published
2020
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190. The updated outcomes of bladder-preserving trimodal therapy using a real-time tumor-tracking radiotherapy system for patients with muscle-invasive bladder cancer

Author

Miyata, Haruka, primary, Osawa, Takahiro, primary, Abe, Takashige, primary, Kikuchi, Hiroshi, primary, Matsumoto, Ryuji, primary, Maruyama, Satoru, primary, Nishioka, Kentaro, primary, Shimizu, Shinichi, primary, Hashimoto, Takayuki, primary, Shirato, Hiroki, primary, and Shinohara, Nobuo, primary

Published
2020
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192. Ramucirumab plus docetaxel versus placebo plus docetaxel in patients with locally advanced or metastatic urothelial carcinoma after platinum-based therapy (RANGE): overall survival and updated results of a randomised, double-blind, phase 3 trial

Author

Petrylak, Daniel P, primary, de Wit, Ronald, additional, Chi, Kim N, additional, Drakaki, Alexandra, additional, Sternberg, Cora N, additional, Nishiyama, Hiroyuki, additional, Castellano, Daniel, additional, Hussain, Syed A, additional, Fléchon, Aude, additional, Bamias, Aristotelis, additional, Yu, Evan Y, additional, van der Heijden, Michiel S, additional, Matsubara, Nobuaki, additional, Alekseev, Boris, additional, Necchi, Andrea, additional, Géczi, Lajos, additional, Ou, Yen-Chuan, additional, Coskun, Hasan Senol, additional, Su, Wen-Pin, additional, Bedke, Jens, additional, Gakis, Georgios, additional, Percent, Ivor J, additional, Lee, Jae-Lyun, additional, Tucci, Marcello, additional, Semenov, Andrey, additional, Laestadius, Fredrik, additional, Peer, Avivit, additional, Tortora, Giampaolo, additional, Safina, Sufia, additional, Garcia del Muro, Xavier, additional, Rodriguez-Vida, Alejo, additional, Cicin, Irfan, additional, Harputluoglu, Hakan, additional, Tagawa, Scott T, additional, Vaishampayan, Ulka, additional, Aragon-Ching, Jeanny B, additional, Hamid, Oday, additional, Liepa, Astra M, additional, Wijayawardana, Sameera, additional, Russo, Francesca, additional, Walgren, Richard A, additional, Zimmermann, Annamaria H, additional, Hozak, Rebecca R, additional, Bell-McGuinn, Katherine M, additional, Powles, Thomas, additional, Wong, Suet-Lai Shirley, additional, Tan, Thean Hsiang, additional, Hovey, Elizabeth Jane, additional, Clay, Timothy Dudley, additional, Wan Ng, Siobhan Su, additional, Rutten, Annemie, additional, Machiels, Jean-Pascal, additional, Dumez, Herlinde, additional, Cheng, Susanna Yee-Shan, additional, Ferrario, Cristiano, additional, Sengeloev, Lisa, additional, Jensen, Niels Viggo, additional, Thibault, Constance, additional, Laguerre, Brigitte, additional, Joly, Florence, additional, Culine, Stéphane, additional, Becht, Catherine, additional, Niegisch, Günter, additional, Stöckle, Michael, additional, Grimm, Marc-Oliver, additional, Schwentner, Christina A, additional, Schultze-Seemann, Wolfgang, additional, Kalofonos, Haralambos, additional, Mavroudis, Dimitrios, additional, Papandreou, Christos, additional, Karavasilis, Vasilis, additional, Révész, Janos, additional, Rosenbaum, Eli, additional, Leibowitz-Amit, Raya, additional, Kejzman, Daniel, additional, Sarid, David, additional, Scagliotti, Giorgio Vittorio, additional, Bracarda, Sergio, additional, Massari, Francesco, additional, Osawa, Takahiro, additional, Miyajima, Naoto, additional, Shinohara, Nobuo, additional, Fukuta, Fumimasa, additional, Ohyama, Chikara, additional, Obara, Wataru, additional, Yamashita, Shinichi, additional, Tomita, Yoshihiko, additional, Kawai, Koji, additional, Fukasawa, Satoshi, additional, Oyama, Masafumi, additional, Yonese, Junji, additional, Nagata, Masayoshi, additional, Uemura, Motohide, additional, Nishimura, Kazuo, additional, Kawakita, Mutsushi, additional, Tsunemori, Hiroyuki, additional, Hashine, Katsuyoshi, additional, Inokuchi, Junichi, additional, Yokomizo, Akira, additional, Nagamori, Satoshi, additional, Lee, Hyo Jin, additional, Park, Se Hoon, additional, Rha, Sun Young, additional, Kim, Yu Jung, additional, Lee, Yun-Gyoo, additional, Vazquez Cortés, Leticia, additional, Lorena Urzua Flores, Claudia, additional, Blaisse, Reinoud J.B., additional, Erdkamp, Fransiscus L.G., additional, Aarts, Maureen J.B., additional, Wojcik-Tomaszewska, Joanna, additional, Tomczak, Piotr, additional, Sikora-Kupis, Bozena, additional, Schenker, Michael, additional, Herzal, Alina Amalia, additional, Udrea, Anghel Adrian, additional, Karlov, Petr, additional, Fomkin, Roman, additional, Gajate Borau, Pablo, additional, Grande, Enrique, additional, Delgado Mignorance, Juan Ignacio, additional, Su, Yu-Li, additional, Li, Jian-Ri, additional, Lin, Chien-Liang, additional, Lin, Chia-Chi, additional, Yeh, Su-Peng, additional, Erman, Mustafa, additional, Urun, Yuksel, additional, Golovko, Yuriy, additional, Bondarenko, Igor, additional, Sinielnikov, Ivan, additional, Crabb, Simon J., additional, Syndikus, Isabel, additional, Huddart, Robert, additional, Sundar, Santhanam, additional, Chowdhury, Simon, additional, Sarwar, Naveed, additional, Flaig, Thomas W., additional, Pan, Chong Xian, additional, Schwarz, James K., additional, Cultrera, Jennifer Lyn, additional, Acs, Peter Istvan, additional, Hainsworth, John D., additional, Herms, Benjamin T., additional, Lawler, William Eyre, additional, and Lowe, Thomas Eugene, additional

Published
2020
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198. The urethral position may shift due to urethral catheter placement in the treatment planning for prostate radiation therapy

Author

Dekura, Yasuhiro, primary, Nishioka, Kentaro, additional, Hashimoto, Takayuki, additional, Miyamoto, Naoki, additional, Suzuki, Ryusuke, additional, Yoshimura, Takaaki, additional, Matsumoto, Ryuji, additional, Osawa, Takahiro, additional, Abe, Takashige, additional, Ito, Yoichi M., additional, Shinohara, Nobuo, additional, Shirato, Hiroki, additional, and Shimizu, Shinichi, additional

Published
2019
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200. Pathological characteristics and clinical course of bladder tumour developing after nephroureterectomy

Author

Abe, Takashige, Shinohara, Nobuo, Harabayashi, Toru, Sazawa, Ataru, Akino, Tomoshige, Ishikawa, Shuhei, Kubota, Kanako, Matsuno, Yoshihiro, Osawa, Takahiro, Shibata, Takeshi, Toyoda, Yutaka, Shinno, Yuichiro, Kamota, Shinji, Minami, Keita, Sakashita, Shigeo, Kumagai, Akira, Takada, Norikata, Togashi, Masaki, Sano, Hiroshi, Mori, Tatsuya, and Nonomura, Katsuya

Published
2010
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