703 results on '"Nukina, Nobuyuki"'
Search Results
152. Decreased protein synthesis of Hsp27 associated with cellular toxicity in a cell model of Machado–Joseph disease
153. Intranuclear Degradation of Polyglutamine Aggregates by the Ubiquitin-Proteasome System
154. 1YP1-08 Cross-seeding fibrillation of Q/N-rich proteins offers new pathomechanism of polyglutamine diseases(1YP1 Early Research in Biophysics Award Candidate Presentations,The 47th Annual Meeting of the Biophysical Society of Japan)
155. Correlation between nuclear accumulation and dysregulation of sodium channel β4 subunit in HD transgenic mice
156. Molecularly targeted therapy for polyglutamine disease
157. 1P-058 Cross-seeding fibrillation of Q/N-rich proteins offers new pathomechanism of polyglutamine diseases(Protein:Property, The 47th Annual Meeting of the Biophysical Society of Japan)
158. Mutant SOD1 impairs axonal transport of choline acetyltransferase and acetylcholine release by sequestering KAP3
159. Complete Loss of Post-translational Modifications Triggers Fibrillar Aggregation of SOD1 in the Familial Form of Amyotrophic Lateral Sclerosis
160. α-Synuclein forms a complex with transcription factor Elk-1
161. Crystal Structure of an Active Form of BACE1, an Enzyme Responsible for Amyloid β Protein Production
162. E6-AP Promotes Misfolded Polyglutamine Proteins for Proteasomal Degradation and Suppresses Polyglutamine Protein Aggregation and Toxicity
163. RNA-binding Protein TLS Is a Major Nuclear Aggregate-interacting Protein in Huntingtin Exon 1 with Expanded Polyglutamine-expressing Cells
164. Pathomechanism of polyglutamine diseases and strategic design for their therapies
165. 2P-076 Molecular dissection of SOD1 aggregation and its structural rationale(The 46th Annual Meeting of the Biophysical Society of Japan)
166. BACE1 modulates filopodia-like protrusions induced by sodium channel β4 subunit
167. Nurr1 is phosphorylated by ERK2 in vitro and its phosphorylation upregulates tyrosine hydroxylase expression in SH-SY5Y cells
168. Synaptic Scaffolding Molecule α Is a Scaffold To Mediate N -Methyl- d -Aspartate Receptor-Dependent RhoA Activation in Dendrites
169. Phosphorylation of ataxin-3 by glycogen synthase kinase 3β at serine 256 regulates the aggregation of ataxin-3
170. Assembly of Lysine 63-linked Ubiquitin Conjugates by Phosphorylated α-Synuclein Implies Lewy Body Biogenesis
171. Floxed allele for conditional inactivation of the voltage-gated sodium channel β1 subunitScn1b
172. Pael-R transgenic mouse crossed with parkin null mouse displays persistent endoplasmic reticulum stress, reduction in complex I activity and dopaminergic neuronal death
173. Dysregulation of β4 gene transcription in the striatum of Huntington Disease transgenic mice
174. Phosphorylated alpha-synuclein contributes to accumulation of ubiquitinated proteins
175. p45 targets the polyglutamine disease protein ataxin-3 to the proteasome
176. 3P059 Elimination of post-translational modifications in SOD1 leads to form pathological amyloid-like aggregates in familial ALS(Proteins-stability, folding, and other physicochemical properties,Oral Presentations)
177. A new membrane microdomain-dependent regulatory mechanism of amyloid precursor protein processing
178. High-throughput RNAi screening for modifiers of mutant huntingtin aggregation in Drosophila melanogaster
179. BACE1 cleavage mediates neurite morphology induced by sodium channel β4 subunit
180. Effects of human apolipoprotein E isoforms on the amyloid β‐protein concentration and lipid composition in brain low‐density membrane domains
181. Expression of Expanded Polyglutamine Proteins Suppresses the Activation of Transcription Factor NFκB
182. Aggregation mechanism of polyglutamine diseases revealed using quantum chemical calculations, fragment molecular orbital calculations, molecular dynamics simulations, and binding free energy calculations
183. rAAV-mediated shRNA ameliorated neuropathology in Huntington disease model mouse
184. Curcumin enhances the polyglutamine-expanded truncated N-terminal huntingtin-induced cell death by promoting proteasomal malfunction
185. Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction
186. 1P018 Structures of binary complex of human BACE1 (β-secretase)(1. Protein structure and dynamics (I),Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)
187. 2P102 Is ALS an amyloid disease? : Molecular mechanism of SOD1 fibrillization(31. Protein folding and misfolding (II),Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)
188. Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis
189. Dynamic expression of Hsp27 in the presence of mutant ataxin-3
190. β Subunits of Voltage-gated Sodium Channels Are Novel Substrates of β-Site Amyloid Precursor Protein-cleaving Enzyme (BACE1) and γ-Secretase
191. BAG-1 associates with the polyglutamine-expanded huntingtin aggregates
192. Co-chaperone CHIP Associates with Expanded Polyglutamine Protein and Promotes Their Degradation by Proteasomes
193. Modulation of monoamine transporter expression and function by repetitive transcranial magnetic stimulation
194. Association of γ-Secretase with Lipid Rafts in Post-Golgi and Endosome Membranes
195. Age-dependent enhancement of hippocampal long-term potentiation in knock-in mice expressing human apolipoprotein E4 instead of mouse apolipoprotein E
196. Identification of ubiquitin-interacting proteins in purified polyglutamine aggregates
197. O3-05-07 Association of γ-secretase components with lipid rafts
198. Gem GTPase and Tau
199. In situ detection of apolipoprotein E ε4 in archival human brain
200. Molecular and functional analysis ofCaenorhabditis elegansCHIP, a homologue of Mammalian CHIP
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