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This paper focuses on advances in the understanding of both the fundamental and applied aspects of nanomaterials. Nanoparticles (titania and graphene oxide) in water-based fluid lying on a surface incorporating the leading edge accretion (or ablation) are analyzed. Entropy generation rate is also considered. The Hall current effect is induced in the flow of hybrid nanofluid, due to which the two-dimensional study converts into three-dimensional space. Similarity transformations convert the equations of momentum, heat transfer, nanoparticles volume fraction and boundary conditions into non-dimensional form. Mathematica software is used to obtain the computation through homotopy analysis method. Analysis is provided through the effects of different parameters on different profiles by sketching the graphs. Flow, heat transfer and nanoparticles concentration in TiO2/H2O, as well as GO-TiO2/H2O, are decreased with increasing the Stefan blowing effect, while entropy generation rate elevates upon increasing each parameter. Both of the velocity components are reduced with increasing the Hall parameter. Streamlines demonstrate that trapping is increased at the left side of the surface. The obtained results are compared with the published work which show the authentication of the present work.

The segregation of neural processing into distinct streams has been interpreted by some as evidence in favour of a modular view of brain function. This implies a set of specialised ‘modules’, each of which performs a specific kind of computation in isolation of other brain systems, before sharing the result of this operation with other modules. In light of a modern understanding of stochastic non-equilibrium systems, like the brain, a simpler and more parsimonious explanation presents itself. Formulating the evolution of a non-equilibrium steady state system in terms of its density dynamics reveals that such systems appear on average to perform a gradient ascent on their steady state density. If this steady state implies a sufficiently sparse conditional independency structure, this endorses a mean-field dynamical formulation. This decomposes the density over all states in a system into the product of marginal probabilities for those states. This factorisation lends the system a modular appearance, in the sense that we can interpret the dynamics of each factor independently. However, the argument here is that it is factorisation, as opposed to modularisation, that gives rise to the functional anatomy of the brain or, indeed, any sentient system. In the following, we briefly overview mean-field theory and its applications to stochastic dynamical systems. We then unpack the consequences of this factorisation through simple numerical simulations and highlight the implications for neuronal message passing and the computational architecture of sentience.

The purpose of the present study is to discuss the effects of graphene nanoparticles on two dimensional magnetohydrodynamic unsteady flow and heat transfer in a thin film Eyring Powell nanofluid past a stretching sheet using velocity slip condition. The contents of graphene nanoparticles increase simultaneously the thermal conductivity and stability when incorporated into the dispersion of water based liquid network. The basic governing equations for velocity and temperature of the Eyring Powell nanofluid film with the boundary conditions easily and simply provide the transformed nonlinear coupled differential equations by employing appropriate similarity transformations. The modeled equations have been evaluated by using an efficient approach through homotopy analysis method which lead to detailed expressions for the velocity profile and temperature distribution. The present work discusses the salient features of all the indispensable parameters of velocity and temperature profiles which have been displayed graphically and illustrated. Skin friction and Nusselt number show an excellent agreement with the published work. The results are useful in the analysis, design of coating and cooling/heating processes.

The conversion of study in two dimensional (x, y) medium into three dimensions space (x, y, z) of a magnetohydrodynamic mixed convective heat and mass transfer boundary layer flow of a thin film second-grade fluid with temperature dependent viscosity and thermal conductivity in the presence of thermal radiation and viscous dissipation past a stretching sheet is analyzed. The occurrence of Hall current in two dimensional (x, y) medium produces a force in z-direction which generates a cross flow in that direction and so the motion is made in three dimensions space (x, y, z). Similarity transformations are used and the transformed system of equations of the problem has been solved by utilizing homotopy analysis method. The salient impacts of the emerging parameters on velocities, temperature and concentration fields have been displayed graphically and illustrated.

A time dependent symmetric flow with heat transmission of a second-grade fluid containing nanoparticles and gyrotactic microorganisms between two parallel plates in two dimensions is explored. Partial differential equations furnish the nonlinear ordinary differential equations due to the usage of relevant similarity transformations. Motion declines due to second grade fluid, energy elevates due to thermophoresis, concentration enhances due to Brownian motion and gyrotactic microorganisms profile elevates due to Peclet number. The unsteadiness parameter β has profound effect on the nanobioconvection flow within the plates. Optimal homotopy asymptotic method (OHAM) is followed to evaluate the transformed systems. Consistency and smoothness between the first and second orders of the optimal homotopy asymptotic method are revealed through graphs. Also, graphs are provided to manifest the impacts of each parameter.

The problem of rapid population growth is one of the main problems effecting countries of the world the reason for this the growth in different environment areas of life commercial, industrial, social, food and educational. Therefore, this study was conducted on the amount of potable water consumed using two models of the two satellite and aerial images of the Kadhimiya District-block 427 and Al-Shu,laa district-block 450 in Baghdad city for available years in the Secretariat of Baghdad (2005, 2011,2013,2015). Through the characteristics of geographic information systems, which revealed the spatial patterns of urban creep by determining the role and buildings to be created, which appear in the picture for the year 2008, 2013, 2015, respectively, compared to buildings and residential areas allocated in 2005. Comparison of each year before to estimate the number the population is the bidder in these years. The amount of water consumed in this period has also been obtained to estimate the amount of water produced for sanitation. The knowledge of growing buildings, increasing population and percentage of increase in the amount of water consumed. Geographic information systems reveal spatial patterns of civilian creep by measuring dimensions in new urban expansion areas from city middle and roads. In various years and in order to knowledge changes that have occurred in particular in the built-up areas, and the urban analyze congestion for periods of lagging and the growth prediction of urban area in the coming years.

Infection with the Epstein-Barr virus (EBV) is associated with several malignancies and autoimmune diseases in humans. The following EBV infection and establishment of latency, recurrences frequently occur resulting in potential viral DNA shedding, which may then trigger the activation of immune pathways. We have previously demonstrated that levels of the pro-inflammatory cytokine IL-17, which is associated with several autoimmune diseases, are increased in response to EBV DNA injection in mice. Whether other pro-inflammatory pathways are induced in EBV DNA pathobiology remains to be investigated. The complexity of mammalian immune systems presents a challenge to studying differential activities of their intricate immune pathways in response to a particular immune stimulus. In this study, we used Drosophila melanogaster to identify innate humoral and cellular immune pathways that are activated in response to EBV DNA. Injection of wild-type adult flies with EBV DNA induced the immune deficiency (IMD) pathway resulting in enhanced expression of the antimicrobial peptide diptericin. Furthermore, EBV DNA increased the number of hemocytes in flies. Conditional silencing of the IMD pathway decreased diptericin expression in addition to curbing of hemocyte proliferation in response to challenge with EBV DNA. Comparatively, upon injecting mice with EBV DNA, we detected enhanced expression of tumor necrosis factor-α (TNFα); this enhancement is rather comparable to IMD pathway activation in flies. This study hence indicates that D. melanogaster could possibly be utilized to identify immune mediators that may also play a role in the response to EBV DNA in higher systems.

Infection with the Epstein-Barr virus (EBV) has been associated with several autoimmune diseases including rheumatoid arthritis (RA). We have previously reported that DNA from this virus enhances production of the pro-autoimmune interleukin 17A (IL-17A) in mice. In this study we assessed the effect of EBV DNA on regulatory T cell programming and examined whether it mediated its effects via Toll-like receptor 9 (TLR9) in mice; moreover, we evaluated whether EBV DNA in humans had similar effects to those seen in mice. For this purpose, we assessed the linearity of the correlation between EBV DNA and IL-17A levels in RA subjects and matched controls. A modulatory effect for the viral DNA was observed for regulatory T cell markers with an inhibitory effect observed for CTLA4 expression in the EBV DNA-treated mice. To examine whether TLR9 mediated the detection of EBV DNA and enhancement of IL-17A production, mouse peripheral blood mononuclear cells were treated with the DNA in the presence or absence of the TLR9 inhibitor ODN 2088. Subsequently, IL-17A production from these cells was assessed. Treatment with the TLR9 inhibitor resulted in a significant decrease in IL-17A production indicating that TLR9 is involved in this pathway. In human subjects, examining the linearity of the correlation between EBV DNA and IL-17A levels in RA subjects showed a propensity for linearity that was not observed in controls. Our data thus indicates that EBV DNA itself acts as a modulator of the Th17 compartment as well as that of regulatory T cell mechanisms. The involvement of TLR9 in the EBV DNA-triggered induction of IL-17A suggests therapeutic targeting of this endosomal receptor in EBV positive subjects with an autoimmune flare-up or possibly for prophylactic purposes.

Bilateral pneumothoraces following unilateral subclavian vein cannulation is a rare complication. It is usually associated with an intrapleural communication which can be congenital or formed following cardiothoracic and mediastinal surgeries, or trauma. The term Buffalo chest was used to define a single chest cavity with no anatomic separation of the two hemithoraces. It is called Buffalo chest because this unique chest anatomy of the American buffalo, or bison, helped hunters to kill them with a single arrow to the chest because the resultant pneumothorax could collapse both lungs. In distinction, the pleural cavities in humans are entirely separated.We describe an 83-year-old female without prior history of cardiothoracic surgery, trauma or lung disease, who underwent dual chamber pacemaker placement using a left subclavian vein access and developed bilateral pneumothoraces following the procedure. The bilateral pneumothoraces were completely resolved with single left-sided thoracostomy tube placement suggesting the patient had “Buffalo chest”. Keywords: Pneumothorax, Buffalo chest, Pacemaker

In this paper, a new approach to the optimum solution based on the Chebyshev distribution for planar array and an improved particle swarm optimization (IPSO) will be considered. The current excitation of each element is used as the optimization factor with an aim to suppress the side lobe level (SLL) and reduce the half power beam width (HPBW) with prescribed nulls. Chebyshev distribution is used to define IPSO search space. The same array is then thinned to find the best distribution of the active, or on, elements in order to obtain the desired requirements.

Pendistribusian produk berperan penting dalam dunia industri. Salah satu usaha yang dapat dilakukan perusahaan untuk mengoptimalkan pendistribusian produk adalah meminimalkan biaya tranportasi melalui penentuan rute optimal kendaraan yang disebut dengan VRP (Vehicle Routing Problem). Tujuan dari VRP adalah menentukan rute optimal yaitu rute dengan jarak minimum untuk mendistribusikan produk kepada konsumen. Salah satu variasi VRP adalah Capacitated Vehicle Routing Problem (CVRP), yaitu VRP dengan kendala kapasitas kendaraan. Kasus CVRP tersebut dapat diselesaikan dengan menggunakan Algoritma Tabu Search. Cara kerja Algoritma Tabu Search dimulai dengan penentuan initial solution menggunakan Nearest Neighbor, evaluasi move menggunakan metode 2-Opt, Relocated, dan Exchange, update Tabu List, kemudian apabila kriteria pemberhentian terpenuhi maka proses Algoritma Tabu Search berhenti jika tidak, maka kembali pada evaluasi move. Proses perhitungan Algoritma Tabu Search dilakukan secara manual dan rancang bangun menggunakan MATLAB pada PT Sinergi Bio Natural. Berdasarkan proses perhitungan manual dan rancang bangun diperoleh dua solusi optimal yaitu rute dengan jarak terpendek dengan total jarak optimal sebesar 101,1 km.

Bangladesh has made significant progress towards elimination of visceral leishmaniasis, and is on track to achieve its target of less than one case per 10,000 inhabitants in each subdistrict in 2017. As the incidence of disease falls, it is likely that the political capital and financial resources dedicated towards the elimination of visceral leishmaniasis may decrease, raising the prospect of disease resurgence. Policy memos may play a crucial role during the transition of the elimination plan from the 'attack' to the 'consolidation' and 'maintenance' phases, highlighting key stakeholders and areas where ongoing investment is crucial. An example of a policy brief is outlined in this paper. The background to the current elimination efforts is highlighted, with emphasis on remaining uncertainties including the impact of disease reservoirs and sustainable surveillance strategies. A stakeholder map is provided outlining the current and projected future activities of key bodies. Identification of key stakeholders subsequently frames the discussion of three key policy recommendations in the Bangladeshi context for the transition to the consolidation and maintenance phases of the elimination program. Recommendations include determining optimal vector control and surveillance strategies, shifting the emphasis towards horizontal integration of disease programs, and prioritising remaining research questions with a focus on operational and technical capacity. Achieving elimination is as much a political as a scientific question. Integrating the discussion of key stakeholders with policy priorities and the research agenda provides a novel insight into potential pathways forwards in the elimination of visceral leishmaniasis in Bangladesh and in the rest of the Indian subcontinent.

In this paper, nanofluid of TiO2/water of concentrations of 0.002% and 0.004% volume was used. This nanofluid was flowing through heat exchanger of shell and concentric double tubes with counter current flow to the hot oil. The thermal conductivity of nanofluid is enhanced with increasing concentrations of the TiO2, this increment was by 19% and 16.5% for 0.004% and 0.002% volume respectively relative to the base fluid (water). Also the heat transfer coefficient of the nanofluid is increased as Reynold's number and nanofluid concentrations increased too. The heat transfer coefficient is increased by 66% and 49% for 0.004% and 0.002% volume respectively relative to the base fluid. This study showed that the friction factor of nanofluid was decreased as Reynold's number increased.

The adsorptions of copper ions from aqueous solution by can papyrus were studied using batch and continuous adsorption. It has been improved surface area and efficiency of the cane papyrus using urea and thiurea at different concentrations through stirring in period of time with mixer. Results proved that cane papyrus very well in the adsorption of metal through the study of important variables and influences such as the contact time, pH in addition to the initial concentration. It was found that the effect of pH at 6 to 7 better than acid or base solution also found that the best time for adsorption to reach equilibrium is 90min and there is no effect of temperature significantly on the results observed, studied the effect of weight of the cane where found that 0.4g best weight. After treatment with urea and thiurea the results improved from the 56% removal by natural cane, 61% for urea modified and 68% for thiurea modified. For continuous adsorption the results shows that when the flow rate increase in constant bed of adsorbent the breakthrough decrease. As well as the best curve was obtained using a cane modified with thiurea weighing 2.5g in a continuous flow rate where the breakthrough curve is start from 25min to 175min. The results was applied to Langmuir and Freundlich adsorption isotherms, the results fitted will to both at correlation coefficients 0.971 and 0.9066 for Langmiur and Freundlich respectively. Pseudo second order was applied and gives better results for adsorption where R2 is 0.9941 while for pseudo first order R2 is 0.136.

Semakin meningkatnya kompetisi global menuntut setiap perusahaan untuk meningkatkan kualitas serta efektifitas kinerja karyawannya yang pada akhirnya diharapkan dapat meningkatkan keuntungan. Penempatan sejumlah X karyawan pada Y pekerjaan dimana masing-masing karyawan mempunyai kompetensi untuk menyelesaikan semua pekerjaan dengan mempertimbangkan beberapa aspek seperti memaksimalkan keuntungan yang diperoleh atau meminimalkan waktu yang diperlukan sebagai akibat dari penempatan karyawan pada pekerjaan dikenal dengan Optimal Assignment Problem. Tujuan dari penulisan ini adalah untuk mencari solusi pada Optimal Assignment Problem dimana aspek yang akan dioptimalkan adalah keuntungan dari penempatan sejumlah karyawan pada pekerjaan yang dapat diperoleh dengan menerapkan konsep teori graf. Dalam hal ini permasalahan dinyatakan sebagai graf bipartit khususnya graf bipartit lengkap berbobot yang menerapkan konsep matching, yaitu pencarian matching sempurna dengan bobot paling optimal. Untuk mencari matching sempurna dengan bobot paling optimal maka dapat digunakan sebuah algoritma optimasi yaitu metode Hungarian. Dengan menggunakan metode Hungarian, diperoleh matching sempurna dengan bobot yang optimal pada graf bipartit lengkap berbobot. Matching dikatakan sempurna jika telah memenuhi semua himpunan simpul dan . Matching yang dihasilkan merupakan solusi dari Optimal Assignment Problem yakni memasangkan seorang karyawan tepat satu dengan sebuah pekerjaan dan bobotnya menyatakan keuntungan optimal yang akan diperoleh oleh suatu perusahaan.

Kasus kebakaran di Indonesia, khususnya Kota Yogyakarta dari tahun ke tahun masih menunjukkan angka yang tinggi. Hal ini mengakibatkan kerugian yang cukup tinggi bagi korban kebakaran. Untuk meminimalisasi terjadinya korban jiwa dan kerugian secara material saat terjadi kebakaran, maka pihak pemadam kebakaran mengupayakan melalui rute terpendek untuk sampai di lokasi kebakaran. Tujuan dari penelitian ini adalah pencarian rute terpendek jalur pemadam kebakaran dari kantor pemadam sampai ke lokasi kebakaran. Permasalahan pencarian rute terpendek jalur pemadam kebakaran secara abstrak dapat digambarkan dengan suatu graf yang merupakan masalah optimasi dalam pencarian rute terpendek (Shortest Path Problem). Pemecahan permasalahan tersebut adalah dengan merepresentasikan peta pemadam kebakaran ke dalam bentuk graf berbobot dan berarah, selanjutnya permasalahan diselesaikan menggunakan Algoritma Branch and Bound. Perhitungan dilakukan secara manual dengan jarak (dalam meter) sebagai bobot perhitungan. Berdasarkan perhitungan menggunakan Algoritma Branch and Bound untuk optimasi jalur pemadam kebakaran Kota Yogyakarta untuk wilayah Kecamatan Umbulharjo menghasilkan solusi rute: Kantor pemadam kebakaran – Jln. Ipda Tut Harsono - Jln. Kusumanegara – Jln. Glagahsari – Kantor Kecamatan Umbulharjo) dengan total jarak 5305 meter atau 5,035 km.

Although some studies have been conducted over the past few decades, the existence of mitochondria-rich cells (MRCs) in reptiles is still obscure. This is the first study to uncover the presence of MRCs in the small intestine of Chinese soft-shelled turtles. In this study, we investigated the ultrastructural characteristics of MRCs and the secretion of different ion transport proteins in the small intestine of Pelodiscus sinensis. Transmission electron microscopy revealed that the ultrastructural features of MRCs are clearly different from those of other cells. The cytoplasmic density of MRCs was higher than absorptive epithelial cells (AECs) and goblet cells (GCs). MRCs possessed abundant heterogeneous mitochondria and an extensive tubular system in the cytoplasm, however, the AECs and GCs completely lacked a tubular system. Statistical analysis showed that the diameter and quantification of mitochondria were highly significant in MRCs. Mitochondrial vacuolization and despoiled mitochondria were closely associated with autophagosomes in MRCs. The multivesicular bodies (MVBs) and the exosome secretion pathway were observed in MRCs. Immunohistochemical staining of ion transport proteins indicated positive immunoreactivity of Na+/K+_ATPase (NKA) and Na+/K+/2Cl− cotransporter (NKCC) at the basal region of the mucosal surface. Likewise, the immunofluorescence staining results showed a strong positive localization of NKA, NKCC, and carbonic anhydrase (CA) at the basal and apical region of the mucosal surface of small intestine. Our findings suggest that MRCs provide support and regulate cellular ions for intestinal homeostasis and provide energy for cellular quality control in intestine.

Iterative methods were employed to obtain solutions of linear and non-linear systems of equations, solutions of differential equations, and roots of equations. In this paper, it was proved that s-iteration with error and Picard−Mann iteration with error converge strongly to the unique fixed point of Lipschitzian strongly pseudo-contractive mapping. This convergence was almost F -stable and F -stable. Applications of these results have been given to the operator equations F x = f and x + F x = f , where F is a strongly accretive and accretive mappings of X into itself.

The thermodynamics of a Carreau nanoliquid thin film embedded with graphene nanoparticles past a stretching sheet is studied in the presence of inclined magnetic field and non-uniform heat source/sink. Graphene is a new two-dimensional amphiphilic macromolecule which has great applications due to its electrical and mechanical properties. The basic constitutive equations of Carreau nanoliquid for velocity and temperature have been used. Similarity transformations are adopted to achieve the nonlinear coupled differential equations accompanying boundary conditions embedded with different parameters. HAM (Homotopy Analysis Method) is used to solve the transformed equations for expressions of velocity and temperature. Graphs are shown which illustrate the effects of various parameters of interest. There exists a nice agreement between the present and published results. The results are useful for the thermal conductivity and in the analysis and design of coating processes.

Chemical reaction in mixed convection magnetohydrodynamic second grade nanoliquid thin film flow through a porous medium containing nanoparticles and gyrotactic microorganisms is considered with entropy generation. The stratification phenomena, heat and mass transfer simultaneously take place within system. Microorganisms are utilized to stabilize the suspended nanoparticles through bioconvection. For the chemical reaction of species, the mass transfer increases. The governing equations of the problem are transformed to nonlinear differential equations through similarity variables, which are solved through a well known scheme called homotopy analysis method. The solution is expressed through graphs and illustrations which show the influences of all the parameters. The residual error graphs elucidate the authentication of the present work.

Food-based dust is considered as combustible dust as they composed of distinct particles, regardless of the size or chemical composition and when suspended in air or any other oxidizing medium over a range of concentrations will present a fire or deflagration hazard. The explosion effect from food-based dust can cause catastrophic consequences because the initial shock wave from the explosion lift up more dust and triggers a chain reaction through the plant. One of the parameters that can enhance the explosion is the particle size of the dust. In this study, the effect of four different particle sizes of tea dust on the dust explosion severity was tested in a confined 20 L explosion bomb. Tea dust tends to explode due to its molecular structure which contains a carbon-hydrogen bond that can release the significant amount of thermal energy. The experimental results showed that the values of Pmax and (dP/dt)max of tea dust were more severe for the particle size of 160 ?m for which are 1.97 bar and 4.97 bar/s before drying and 2.09 bar and 7.01 bar/s after drying process. The finer dust reacted more violently than coarser ones. As particle size decreases, the rate of explosion pressure change increases, as long as the size is capable of supporting combustion.

An ideal hernia mesh is one that absorbs drugs and withstands muscle forces after mesh implantation. Polypropylene (PP) mesh devices have been accepted as a standard material to repair abdominal hernia, but the hydrophobicity of PP fibers makes them unsuitable to carry drugs during the pre-implantation of PP meshes. In this study, for the first time, one-step functionalization of PP mesh surfaces was performed to incorporate bio-inspired polydopamine (PDA) onto PP surfaces. All PP mesh samples were dipped in the same concentration of dopamine solution. The surface functionalization of PP meshes was performed for 24 h at 37 °C and 80 rpm. It was proved by scanning electron microscopic (SEM) images and Fourier Transform Infrared Spectroscopy (FTIR) results that a thin layer of PDA was connected with PP surfaces. Moreover, water contact angle results proved that surface functionalized PP meshes were highly hydrophilic (73.1°) in comparison to untreated PP mesh surfaces (138.5°). Thus, hydrophilic PP meshes with bio-inspired poly-dopamine functionalization could be a good choice for hernia mesh implantation.

Traffic congestion is a problem which is often found in big cities in Indonesia. This requires a range of solutions, one of them with the settings of the traffic light. Traffic light arrangement can be completed with graph theory. Part of graph theory a graph coloring is used. Staining graf three i.e. coloring is differentiated into a knot, staining the sides, and staining region. This research examines the arrangements about traffic light using colorization algorithm Welch knot with Powell. The intersection of Data represented in the graph, which is then solved by coloring the vertices, then look for the value of the effective duration of the time compared to a traffic light settings occur at several intersections in Yogyakarta. Completion of traffic light arrangement using staining nodes provide alternative solutions duration lit the red light and green light is more effective than the secondary data at several intersections in Yogyakarta.

Gangguan gelombang transmisi radio sering terjadi dikarenakan kesenjangan antara bandwith frekuensi yang tersedia dan tingginya permintaan frekuensi. Telaah pewarnaan graf khususnya algoritma Welsh-Powell diharapkan dapat memberikan alternatif solusi permasalahan tersebut. Penelitian ini mengkaji optimasi radio frequency unit berbasis interferensi kanal menggunakan pendekatan upper bound bilangan kromatik. Data mengenai persebaran radio akan direpresentasikan dalam bentuk graf dengan mempertimbangkan tingkat interferensi yaitu kuat medan listrik, selanjutnya akan dianalisis menggunakan pewarnaan graf dengan algoritma Welsh-Powell. Hasil penelitian memberikan alternatif model distribusi frekuensi radio yang optimal.

Present study was aimed to screening the population of 25 wheat genotypes from Baluchistan region of Pakistan along with five commercial cultivars for leaf rust adult plant resistance (APR) through gene postulation using natural inoculation of Puccinia triticina Erikss local pathotype. Infection severity was recorded on scale in comparison with susceptible control "Morroco" cultivar. On the basis of phenotypic score, seven accessions and four varieties (Zardana-89, Sariab-92, Zarlashta-99 and Raskoh-05) with AUDPC values up to 20% were characterized as resistant genotypes. Coefficient of infection (CI) score ranged from 0-10 for some accessions and cultivars showing high level of adult plant resistance. Furthermore, bi-allelic STS marker csLV34 having close linkage with Lr34 (0.4cM). This marker amplified one gene specific allele of 150bp in 21 genotypes, including 19 accessions and two commercial varieties (Sariab-92 and Zarghoon-79) which confirmed presence of Lr34 gene conferring adult plant resistance against leaf rust. The rust pathogenicity scale varied for accessions from resistant to moderately susceptible. However, beside Lr34, phenotypic gene postulation, in combination with marker assisted selection for leaf rust resistance, has revealed presence of some other unknown resistance genes in local wheat germplasm which signified its use in wheat improvement programs both locally and abroad.

The paper uses the Direct Synthesis (DS) method for tuning the Proportional Integral Derivative (PID) controller for controlling the DC servo motor. Two algorithms are presented for enhancing the performance of the suggested PID controller. These algorithms are Back-Propagation Neural Network and Particle Swarm Optimization (PSO). The performance and characteristics of DC servo motor are explained. The simulation results that obtained by using Matlab program show that the steady state error is eliminated with shorter adjusted time when using these algorithms with PID controller. A comparative between the two algorithms are described in this paper to show their effectiveness, which is found that the PSO algorithm gives better results to improve the PID controller for controlling the DC servo motor compared to the neural network algorithm. -

A computational approach was used to analyze the FTIR spectra of a wide range of treated and untreated lignocellulosic biomass (coconut husk, banana trunk, sago hampas, rice husk, and empty fruit bunch). The biomass was treated with strong sulphuric acid and NaOH, respectively. A total of 87 spectra were obtained in which the absorption bands were de-convoluted automatically, generating a peak table of 87 rows and 60 columns. Square roots were taken of the peak values, with further standardization prior to Principal Component Analysis (PCA) for data exploration. In a scores plot, the treated and untreated biomass were distinguishable along the two main axes, PC1 and PC2. Examining the absorption bands corresponding to lignocellulosic components indicated that the acid pretreatment had resulted in dissolution and degradation of hemicelluloses and lignin, confirmed typically by disappearance of bands. The alkali treatment however was not as rigorous as the acid treatment, as some characteristic bands of hemicelluloses and lignin were enhanced, suggesting condensation of the degraded polysaccharides. The computer-assisted analysis of the FTIR spectra allowed efficient and simultaneous comparisons of lignocellulosic compositions present in various treated and untreated biomass. This represents an improvement relative to the conventional methods, since a large dataset can be handled efficiently and individual peaks can be examined.

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function 𝑄𝑥with constraints𝜇 𝑇 𝑥 ≥ 𝑅and𝐴𝑥 = 𝑏. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis.

The present study deals with the effects of natural fibers on some mechanicalproperties of the Epoxy composite. This research was carried out by reinforcingthe matrix (Epoxy) resin with natural material (cane sugar fibers) and syntheticfibers (chopped carbon fibers). The natural fibers were exposure to chemicaltreatment before reinforcement.The hybrid composites contain of chopped carbon and cane sugar fibers isproduced using hand lay method. Each sample was reinforced with differentvolume fraction such as 30%, 20%, and 10%. After preparation of compositematerial some of the mechanical properties flexural and impact tests were studiedof prepared samples.Cane sugar composite has the higher values (of flexural strength 490.77 MPa andof impact strength 93.92 KJ/m2 ) than chopped carbon composites (flexuralstrength 93.19 MPa and impact strength 23.92 KJ/m2). It was found that theadditions of natural fibers (cane sugar) to chopped carbon fibers improve of themechanical properties of hybrid composites

This paper present a simple method for reducing the linear higher order systems. The coefficient of the reduction model is obtained by using the modified dominant pole technique, while the coefficients of the numerator are obtained by reduced order model. Linear Quadratic Regulator (LQR) is used to design a controller for the higher order system depended on the linear reducing equations. LQR without and with integral effect method are used and compared for controlling the higher order systems. The LQR controller are designed and simulated using MATLAB/Simulink. Simulation results show that both the controllers are capable of controlling the systems successfully. The LQR with integral gives the better performance, compared to when the system without it. the LQR controller scheme with smith predictor connection is suggested in order to maintain the stability of the higher order plant in addition to improve the performance of the controlled system. The simulation results for this scheme are tested with two higher order time delay systems to illustrate the efficient performance for the proposed control scheme.

The magnetohydrodynamic thin film nanofluid sprayed on a stretching cylinder with heat transfer is explored. The spray rate is a function of film size. Constant reference temperature is used for the motion past an expanding cylinder. The sundry behavior of the magnetic nano liquid thin film is carefully noticed which results in to bring changes in the flow pattern and heat transfer. Water-based nanofluids like Al 2 O 3 -H 2 O and CuO-H 2 O are investigated under the consideration of thin film. The basic constitutive equations for the motion and transfer of heat of the nanofluid with the boundary conditions have been converted to nonlinear coupled differential equations with physical conditions by employing appropriate similarity transformations. The modeled equations have been computed by using HAM (Homotopy Analysis Method) and lead to detailed expressions for the velocity profile and temperature distribution. The pressure distribution and spray rate are also calculated. The comparison of HAM solution predicts the close agreement with the numerical method solution. The residual errors show the authentication of the present work. The CuO-H 2 O nanofluid results from this study are compared with the experimental results reported in the literature showing high accuracy especially, in investigating skin friction coefficient and Nusselt number. The present work discusses the salient features of all the indispensable parameters of spray rate, velocity profile, temperature and pressure distributions which have been displayed graphically and illustrated.

ABSTRACT The kinetics of chlorination of N-acetylglycin (AG) with sodium N-chloro -p- toluene sulphonamide (CAT) in presence of HCL has been studied at 318 oK. The reaction rate shows afirst –order dependence each on [CAT] and [H+] and zero order dependence on [AG]. The Variation of ionic strength of the medium or chloride ion had no significant effect on the reaction rate. Addition of P-TSA is marginally affected the reaction rate. The rate increase with decreasing dielectric constant of the medium. The stiochiometry of the reaction was found 1:1 and the oxidation producte were identified. The thermodynamic parameters were computed. The mechanism proposed and the derived rate law were in agreement with the observed kinetics.

Background: Orthodontic force is considered to stimulate cells in the periodontium to release many mediators such as cytokines which play a responsible role for periodontal and alveolar bone remodeling, bone resorption and new bone deposition. Aim of this study was carried out to estimate changes of the (interleukin-one beta, tumor necrosis factor alpha and C-reactive protein) levels in unstimulated whole saliva during the leveling stage of orthodontic tooth movement. Materials and methods: The sample consisted of thirty adult patients (12 males and 18 females) with ages ranges (19-23) years. Each sample had Class I and Class II malocclusion dental classification and required bilateral extraction of their maxillary first premolars, underwent a session of professional oral hygiene and received oral hygiene instructions before and during the period of study, one month later fixed orthodontic appliance were placed in the upper arch by using 0.014 nickel titanium arch wire. The unstimulated whole saliva was taken from each sample immediately before placement of the appliance (baseline), and at (after1hour, after one week and after two week) following placement of the fixed orthodontic appliance. In addition the plaque index and gingival index were recorded during the interval periods of this study to assess oral cleanliness. The interleukin one beta and tumor necrosis factor-alpha were determined by enzyme linked immunosorbent assay, while the C-reactive protein was determined by latex agglutination. Results: The results of the present study found the mean value of both salivary (interleukin-one beta and tumor necrosis factor -alpha) were highest at (after1hour) followed by at (after one week) then at (after two week) than the baseline with highly statistical significant differences (P< 0.01) among males, females and total samples, in addition there were no statistical significant differences between males and females (P>0.05). While the mean values of C-reactive protein were higher at (after 1hour) only with highly significant differences (P< 0.01) among females and total samples while only significant difference (P

T and π networks find applications in the transmission line representations and in the simple filter design. These networks have the problem of a nonconstant image impedance over all the passband response . In this paper, new structures for T and π-networks are suggested to improve their performance. The new structures employ the concept of m-derived technique. The simulation examples demonstrate the effctiveness of the developed methodologies

Background: Tonsillectomy is a commonly performed surgical procedure. There are several operative methods but the superiority of one over the other has not been clearly demonstrated. The aim of this study was to compare the morbidity associated with tonsillectomy using two different techniques for hemostasis – silk ligation versus diathermy. Material and methods: This was an experimental study conducted at ENT Department of Khyber Teaching Hospital Peshawar and Gomal Medical College D.I.Khan, from January 2003 to December 2004. Results of the two groups i.e. tonsillectomy using silk ligation or diathermy for hemostasis were studied. Results: Tonsillectomy of 180 patients was performed; 130 (72.22%) male and 50 (27.77%) female. Bipolar diathermy was used in 60 cases to achieve hemostasis while silk ligation in 120. The mean operation time was 15 minutes with bipolar diathermy as compared to 30 minutes with silk ligation. Analgesia requirement in first 24 hours was equal in both groups. Primary hemorrhage was noticed in 4 (6.66%) cases when hemostasis was achieved using bipolar diathermy and in 8 (6.66%) cases when silk was used. Secondary hemorrhage was noticed in 8 (13.33%) cases with bipolar diathermy as compared to only 5 (4.16%) when silk ligation was done. Conclusion: Less operative time is taken by bipolar diathermy method as compared to the tonsillectomy using silk ligation for hemostasis. Chances of primary hemorrhage are equal but secondary hemorrhage is significantly less with silk ligation.

Abstract Background Previous studies suggest a link between gut microbiota and the development of ulcerative colitis (UC) and irritable bowel syndrome (IBS). Our aim was to investigate any quantitative differences in faecal bacterial compositions in UC and IBS patients compared to healthy controls, and to identify individual bacterial species that contribute to these differences. Methods Faecal microbiota of 13 UC patients, 11 IBS patients and 22 healthy volunteers were analysed by PCR-Denaturing Gradient Gel Electrophoresis (DGGE) using universal and Bacteroides specific primers. The data obtained were normalized using in-house developed statistical method and interrogated by multivariate approaches. The differentiated bands were excised and identified by sequencing the V3 region of the 16S rRNA genes. Results Band profiles revealed that number of predominant faecal bacteria were significantly different between UC, IBS and control group (p < 10-4). By assessing the mean band numbers in UC (37 ± 5) and IBS (39 ± 6), compared to the controls (45 ± 3), a significant decrease in bacterial species is suggested (p = 0.01). There were no significant differences between IBS and UC. Biodiversity of the bacterial species was significantly lower in UC (μ = 2.94, σ = 0.29) and IBS patients (μ = 2.90, σ = 0.38) than controls (μ = 3.25, σ = 0.16; p = 0.01). Moreover, similarity indices revealed greater biological variability of predominant bacteria in UC and IBS compared to the controls (median Dice coefficients 76.1% (IQR 70.9 - 83.1), 73.8% (IQR 67.0 - 77.5) and 82.9% (IQR 79.1 - 86.7) respectively). DNA sequencing of discriminating bands suggest that the presence of Bacteroides vulgatus, B. ovatus, B. uniformis, and Parabacteroides sp. in healthy volunteers distinguishes them from IBS and UC patients. DGGE profiles of Bacteroides species revealed a decrease of Bacteroides community in UC relative to IBS and controls. Conclusion Molecular profiling of faecal bacteria revealed abnormalities of intestinal microbiota in UC and IBS patients, while different patterns of Bacteroides species loss in particular, were associated with UC and IBS.

Life-history information is necessary for effective conservation, aquaculture development and broodstock management of fishing populations, especially for fish with significant economic exploitation. Aiming to characterise the life-history traits in relation to the environmental parameters of the long-whiskered catfish, Mystus aor, a commercially important species from Kaptai Lake, Bangladesh, different life-history data were analysed. The monthly condition factor (K) ranged from 1.15 to 1.41, and the relative condition factor (Kn) ranged from 0.14 to 0.25. The estimated relative fecundity was 18474-55504 eggs/per fish, and the maximal oocyte diameter was found in May (0.83 ± 0.11μm). The lengths at first sexual maturity (Lm) for male and female M. aor were 49.5 cm and 54.1 cm, respectively. The GSI was peaked in May for both males and females, and histological analysis also revealed the presence of yolk granules and several mature spermatids in April and May in both sexes. Analysis of environmental data over 40 years in the Kaptai lake ecosystem indicate the significant increase in the precipitation rate in spawning month which is highly correlated with the spawning season. The findings of the current study will serve as a baseline for the conservation and broodstock management in the Kaptai Lake of Bangladesh., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2024 Noor et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

The field of propellants has recently witnessed dynamic shift, including advancements in propulsion technology and a growing emphasis on the development of environmentally friendly propellants. Nitrate ester (NE) are extensively used in solid propellants, exhibiting chemical instability as they undergo decomposition reactions. Stabilization is a crucial aspect in propellant, ensuring the safety and reliable performance of energetic materials. Stabilizer plays a vital role in inhibiting or slowing down the autocatalytic decomposition reaction of propellants. In response to grow health and environmental concerns, there is a continuous effort to explore and evaluate green stabilizers designed to replace traditional stabilizers, which have been associated with adverse environmental impacts. Therefore, this study aimed to provide an overview of the current research carried out in the field of NE-based propellants, emphasizing the most significant work undertaken on green stabilizer materials for NE-based propellants. A comprehensive review of various environmentally friendly and low-toxicity stabilizers employed in propellants are presented, and their effects on the stability and shelf-life performance of NE-based propellants are discussed. Furthermore, this paper delves into the stabilization mechanisms of green stabilizers to mitigate decomposition reactions, thereby preventing unwanted side effects and ensuring long-term storage stability. Through a comprehensive review of recent developments, the manuscript highlights the successes and challenges associated with the incorporation of green stabilizers in NE-based propellants formulations. Finally, the review concludes by outlining future research directions and opportunities for innovation in sustainable and green stabilizers as well as key issues that need to be addressed and resolved. The comprehensive review and insights provided in this study contribute to the ongoing efforts in developing safer and more sustainable propellant technologies., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2024 The Authors.)

In this present study, characteristics and structure-function relationship of an organophosphate-degrading enzyme from Bacillus sp. S3wahi were described. S3wahi metallohydrolase, designated as S3wahi-MH (probable metallohydrolase YqjP), featured the conserved αβ/βα metallo-β-lactamase-fold (MBL-fold) domain and a zinc bimetal at its catalytic site. The metal binding site of S3wahi-MH also preserves the H-X-H-X-D-H motif, consisting of specific amino acids at Zn1 (Asp69, His70, Asp182, and His230) and Zn2 (His65, His67, and His137). The multifunctionality of S3wahi-MH was demonstrated through a steady-state kinetic study, revealing its highest binding affinity (K M ) and catalytic efficiency (k cat /K M ) for OP compound, paraoxon, with values of 8.09 × 10 -6  M and 4.94 × 10 5  M -1  s -1 , respectively. Using OP compound, paraoxon, as S3wahi-MH native substrate, S3wahi-MH exhibited remarkable stability over a broad temperature range, 20 °C - 60 °C and a broad pH tolerance, pH 6-10. Corresponded to S3wahi-MH thermal stability characterization, the estimated melting temperature (T m ) was found to be 72.12 °C. S3wahi-MH was also characterized with optimum catalytic activity at 30 °C and pH 8. Additionally, the activity of purified S3wahi-MH was greatly enhanced in the presence of 1 mM and 5 mM of manganese (Mn 2+ ), showing relative activities of 1323.68 % and 2073.68 %, respectively. The activity of S3wahi-MH was also enhanced in the presence of DMSO and DMF, showing relative activities of 270.37 % and 307.41 %, respectively. The purified S3wahi-MH retained >60 % residual activity after exposure to non-ionic Tween series surfactants. Nevertheless, the catalytic activity of S3wahi-MH was severely impacted by the treatment of SDS, even at low concentrations. Considering its enzymatic properties and promiscuity, S3wahi-MH emerges as a promising candidate as a bioremediation tool in wide industrial applications, including agriculture industry., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier B.V. All rights reserved.)

The incorporation of intermittent renewable energy sources into a consistently controlled power transmission system hinges on advancements in energy storage technologies. Sodium ion batteries (SIBs) are emerging as a primary and viable alternative material due to their electrochemical activity, presenting a potential replacement for the next generation of lithium-ion battery (LIB) energy storage materials. However, this transition may necessitate significant alterations in the anode material, given the incompatibility of the current anode with sodium ions and the electrolyte. This review provides a comprehensive summary of various anode materials employed in SIBs, categorized according to their storage mechanisms. Additionally, it explores the growing focus on utilizing hard carbon as an anode material, driven by factors such as its relatively high specific capacity compared to graphite, cost-effective production, and eco-friendly properties as it can be derived from biomass. The review further addresses recent progress in hard carbon, detailing production methods, modifications, challenges, limitations in integrating hard carbon into the anode of SIBs, and suggests potential directions for future research., Competing Interests: The authors declare the following financial interests/personal relationships which may be considered as potential competing interests:Siti Aminah Mohd Noor reports financial support and administrative support were provided by 10.13039/501100012322National Defence University of Malaysia. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2024 Published by Elsevier Ltd.)

Chlorine gas is extensively utilised in industries as both a disinfectant and for wastewater treatment. It has a pungent and irritating odour that is comparable with that of bleach and can cause serious health issues such as headaches and breathing difficulties. Hence, efficiently, and accurately monitoring chlorine gas is critical to ensure that no undesirable incidents occur. Due to its remarkable characteristics, numerous researchers have explored the potential of ferrite nanoparticles as a sensing material for chlorine gas detection. Among several ferrite nanoparticles, nickel ferrite (NiFe 2 O 4 ) is extensively studied as an inverse spinel structured magnetic material that may be ideal for sensing applications. However, the magnetic characteristics of NiFe 2 O 4 cause agglomeration, which necessitates the use of a substrate for stabilisation. Therefore, nanocellulose (NC), as a green and eco-friendly substrate, is ideal for stabilising bare nickel ferrite nanoparticles. In a novel experiment, nickel ferrite was loaded onto NC as a substrate using in situ deposition. The structure was confirmed by X-ray Diffraction (XRD) analysis, while elemental composition was verified by Energy dispersive X-ray (EDX) analysis. Gas sensing properties were determined by evaluating sensitivity as a function of various regulating factors, such as the amount of nickel ferrite, gas concentration, repeatability, and reusability. In the evaluation, 0.3 g nickel ferrite showed superior response and sensitivity than those of other samples. The achieved response time was around 40 s, while recovery time was about 50 s. This study demonstrates the potential of a nickel ferrite/nanocellulose-based nanocomposite to efficiently monitor chlorine gas.

The wide availability and diversity of dangerous microbes poses a considerable problem for health professionals and in the development of new healthcare products. Numerous studies have been conducted to develop membrane filters that have antibacterial properties to solve this problem. Without proper protective filter equipment, healthcare providers, essential workers, and the general public are exposed to the risk of infection. A combination of nanotechnology and biosorption is expected to offer a new and greener approach to improve the usefulness of polysaccharides as an advanced membrane filtration material. Nanocellulose is among the emerging materials of this century and several studies have proven its use in filtering microbes. Its high specific surface area enables the adsorption of various microbial species, and its innate porosity can separate various molecules and retain microbial objects. Besides this, the presence of an abundant OH groups in nanocellulose grants its unique surface modification, which can increase its filtration efficiency through the formation of affinity interactions toward microbes. In this review, an update of the most relevant uses of nanocellulose as a new class of membrane filters against microbes is outlined. Key advancements in surface modifications of nanocellulose to enhance its rejection mechanism are also critically discussed. To the best of our knowledge, this is the first review focusing on the development of nanocellulose as a membrane filter against microbes.

Conducting polymers have been widely used in electrochemical sensors as receptors of the sensing signal's analytes and transducers. Polypyrrole (PPy) conducting polymers are highlighted due to their good electrical conductive properties, ease in preparation, and flexibility of surface characteristics. The objective of this review paper is to discuss the theoretical background of the two main types of electrochemical detection: impedimetric and voltammetric analysis. It also reviews the application and results obtained from these two electrochemical detections when utilizing PPy as a based sensing material in electrochemical sensor. Finally, related aspects in electrochemical sensor construction using PPy will also be discussed. It is anticipated that this review will provide researchers, especially those without an electrochemical analysis background, with an easy-to-understand summary of the concepts and technologies used in electrochemical sensor research, particularly those interested in utilizing PPy as a based sensing material.

Acephate (Ac) is an organophosphate (OP) compound, which is able to inhibit the activity of acetylcholinesterase. Thus, the aim of this study was to optimize the detection of Ac using a thiolated acephate binding aptamer-citrate capped gold nanoparticle (TABA-Cit-AuNP) sensor that also incorporated an image processing technique. The effects of independent variables, such as the incubation period of TABA-Cit-AuNPs (3-24 h) for binding TABA to Cit-AuNPs, the concentration of phosphate buffer saline (PBS) (0.001-0.01 M), the concentration of thiolated acephate binding aptamer (TABA) (50-200 nM), and the concentration of magnesium sulphate (MgSO 4 ) (1-300 mM) were investigated. A quadratic model was developed using a central composite design (CCD) from response surface methodology (RSM) to predict the sensing response to Ac. The optimum conditions such as the concentration of PBS (0.01 M), the concentration of TABA (200 nM), the incubation period of TABA-Cit-AuNPs (3 h), and the concentration of MgSO 4 (1 mM) were used to produce a TABA-Cit-AuNPs sensor for the detection of Ac. Under optimal conditions, this sensor showed a detection ranging from 0.01 to 2.73 μM and a limit of detection (LOD) of 0.06 μM. Real sample analysis demonstrated this aptasensor as a good analytical method to detect Ac., Competing Interests: There are no conflicts to declare., (This journal is © The Royal Society of Chemistry.)

Chemical contaminants such as heavy metals, dyes, and organic oils seriously affect the environment and threaten human health. About 2 million tons of waste is released every day into the water system. Heavy metals are the largest contributor which cover about 31% of the total composition of water contaminants. Every day, approximately 14 000 people die due to environmental exposure to selected chemicals. Removal of these contaminants down to safe levels is expensive, high energy and unsustainable by current approaches such as oxidation, biodegradation, photocatalysis, precipitation, reverse osmosis and adsorption. A combination of biosorption and nanotechnology offers a new way to remediate these chemical contaminants. Nanostructured materials are proven to have higher adsorption capacities than the same material in its larger-scale form. Nanocellulose is very promising as a high-performance bioadsorbent due to its interesting characteristics of high adsorption capacity, high mechanical strength, hydrophilic surface chemistry, renewability and biodegradability. It has been proven to have higher adsorption capacity and better binding affinity than other similar materials at the macroscale. The high specific surface area and abundance of hydroxyl groups within lead to the possible functionalization of this material for decontamination purposes. Several research papers have shown the effectiveness of nanocellulose in the remediation of chemical contaminants. This review aims to provide an overview of the most recent developments regarding nanocellulose as an adsorbent for chemical contamination remediation. Recent advancements regarding the modification of nanocellulose to enhance its adsorption efficiency towards heavy metals, dyes and organic oils were highlighted. Moreover, the desorption capability and environmental issue related to every developed nanocellulose-based adsorbent were also tackled., Competing Interests: There are no conflicts of interest to declare., (This journal is © The Royal Society of Chemistry.)

In this study, mitochondrial DNA analysis using 16S ribosomal DNA (rDNA) was performed to investigate the phylogeny relationship of Trichiurus lepturus in the Persian Gulf compared to the other investigated area. The amplification of 16S rDNA resulted in a product of 600 bp in all samples. The results showed that the isolated strain belongs to T. lepturus showing 42 divergence sites among the same reported partial sequences of 16S rRNA gene from the other area (West Atlantic and Indo-Pacific area). Phylogeny results showed that all 18 haplotypes of the species clustered into five clades with reasonably high bootstrap support of values (>64%). Overall, the tree topology for both phylogenetic and phenetic trees for 16S rDNA was similar. Both trees exposed two major clusters, one wholly containing the haplotypes of the T. lepturus species belonging to Indo-Pacific area with two major sister groups including Persian Gulf specimen and the other cleared the Western Atlantic and Japan individuals clustered in another distinct clade supporting the differentiation between the two areas. Phylogenic relationship observed between the Persian Gulf and the other Indo-Pacific Individuals suggested homogeneity between two mentioned areas.

The case report of a young male with Endocarditis caused by Moraxella lacunata is presented. Although a well recognized cause of keratitis, conjunctivitis, and sinusitis; very few cases of endocarditis by this rare pathogen are reported in literature. Patient showed a prompt response when empirical therapy was de-escalated to penicillin, after receiving culture and sensitivity report from Microbiology department.