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576 results on '"NUÑEZ, JULIO"'

151. Implications of worsening renal function before hospitalization for acute heart failure

Author

Wettersten, Nicholas, primary, Duff, Stephen, additional, Horiuchi, Yu, additional, van Veldhuisen, Dirk J., additional, Mueller, Christian, additional, Filippatos, Gerasimos, additional, Nowak, Richard, additional, Hogan, Christopher, additional, Kontos, Michael C., additional, Cannon, Chad M., additional, Müeller, Gerhard A., additional, Birkhahn, Robert, additional, Taub, Pam, additional, Vilke, Gary M., additional, McDonald, Kenneth, additional, Mahon, Niall, additional, Nuñez, Julio, additional, Briguori, Carlo, additional, Passino, Claudio, additional, Maisel, Alan, additional, Murray, Patrick T., additional, and Ix, Joachim H., additional

Published
2022
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152. Galectin-3, Acute Kidney Injury and Myocardial Damage in Patients With Acute Heart Failure

Author

HORIUCHI, YU, primary, WETTERSTEN, NICHOLAS, additional, VAN VELDHUISEN, DIRK J., additional, MUELLER, CHRISTIAN, additional, FILIPPATOS, GERASIMOS, additional, NOWAK, RICHARD, additional, HOGAN, CHRISTOPHER, additional, KONTOS, MICHAEL C., additional, CANNON, CHAD M., additional, MÜELLER, GERHARD A., additional, BIRKHAHN, ROBERT, additional, TAUB, PAM, additional, VILKE, GARY M., additional, MCDONALD, KENNETH, additional, MAHON, NIALL, additional, NUÑEZ, JULIO, additional, BRIGUORI, CARLO, additional, PASSINO, CLAUDIO, additional, DUFF, STEPHEN, additional, MAISEL, ALAN, additional, and MURRAY, PATRICK T., additional

Published
2022
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153. Early carbohydrate antigen 125 as a mortality predictor in hospitalized patients with coronavirus disease 2019

Author

Moreno-Perez, Oscar, primary, Nuñez, Julio, additional, Sandin-Rollan, Miriam, additional, Arrarte, Vicente, additional, Boix, Vicente, additional, Reus, Sergio, additional, Pinargote-Celorio, Hector, additional, Ribes, Isabel, additional, Alfayate, Rocio, additional, Llorca-Santos, Maria Belen, additional, Martinez-Garcia, Maria Angeles, additional, Chico-Sánchez, Pablo, additional, and Merino, Esperanza, additional

Published
2022
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154. Endotrophin, a Collagen VI Formation–Derived Peptide, in Heart Failure

Author

Chirinos, Julio A., primary, Zhao, Lei, additional, Reese-Petersen, Alexander L., additional, Cohen, Jordana B., additional, Genovese, Federica, additional, Richards, A. Mark, additional, Doughty, Robert N., additional, Díez, Javier, additional, González, Arantxa, additional, Querejeta, Ramón, additional, Zamani, Payman, additional, Nuñez, Julio, additional, Wang, Zhaoqing, additional, Ebert, Christina, additional, Kammerhoff, Karl, additional, Maranville, Joseph, additional, Basso, Michael, additional, Qian, Chenao, additional, Rasmussen, Daniel G.K., additional, Schafer, Peter H., additional, Seiffert, Dietmar, additional, Karsdal, Morten A., additional, Gordon, David A., additional, Ramirez-Valle, Francisco, additional, and Cappola, Thomas P., additional

Published
2022
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155. Mortality and Heart Failure Risk Reductions in Patients Treated With Sacubitril–Valsartan in Clinical Trials

Author

Cordero, Alberto, primary, Nuñez, Julio, additional, Bertomeu-González, Vicente, additional, Fácila, Lorenzo, additional, Quintanilla, Mª Amparo, additional, Rodríguez-Mañero, Moisés, additional, Escribano, David, additional, Valle, Alfonso, additional, de la Espriella, Rafael, additional, Torres-Llergo, Javier, additional, Bayés-Genís, Antoni, additional, and González-Juanatey, José R., additional

Published
2022
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157. Effect of ischemic postconditioning on microvascular obstruction in reperfused myocardial infarction. Results of a randomized study in patients and of an experimental model in swine

Author

Bodi, Vicente, Ruiz-Nodar, Juan M., Feliu, Eloisa, Minana, Gema, Nunez, Julio, Husser, Oliver, Martinez-Elvira, Javier, Ruiz, Amparo, Bonanad, Clara, Monmeneu, Jose V., Lopez-Lereu, Maria P., Forteza, Maria J., de Dios, Elena, Hervas, Arantxa, Moratal, David, Gomez, Cristina, Mainar, Luis, Sanchis, Juan, Mainar, Vicente, Valencia, Jose, Diaz, Ana, Noguera, Inmaculada, Chaustre, Fabian, and Chorro, Francisco J.

Published
2014
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159. Impact of dapagliflozin on cardiac remodelling in patients with chronic heart failure: The DAPA‐MODA study.

Author

Pascual‐Figal, Domingo A., Zamorano, J. Luis, Domingo, Mar, Morillas, Herminio, Nuñez, Julio, Cobo Marcos, Marta, Riquelme‐Pérez, Alejandro, Teis, Albert, Santas, Enrique, Caro‐Martinez, Cesar, Pinilla, Jose Manuel, Rodriguez‐Palomares, Jose F., Dobarro, David, Restrepo‐Córdoba, M. Alejandra, González‐Juanatey, J. Ramón, Bayés Genís, Antoni, Figal, Domingo Pascual, Riquelme, Alejandro Pérez, Caro, Cesar, and Vicente, Álvaro Hernández

Subjects
BRAIN natriuretic factor, HEART failure patients, SODIUM-glucose cotransporter 2 inhibitors, DAPAGLIFLOZIN, CARDIAC patients
Abstract

Aims: Dapagliflozin improves the prognosis of patients with heart failure (HF), regardless of left ventricular ejection fraction (LVEF). However, its effect on cardiac remodelling parameters, specifically left atrial (LA) remodelling, is not well established. Methods and results: The DAPA‐MODA trial (NCT04707352) is a multicentre, single‐arm, open‐label, prospective and interventional study that aimed to evaluate the effect of dapagliflozin on cardiac remodelling parameters over 6 months. Patients with stable chronic HF receiving optimized guideline‐directed therapy, except for any sodium–glucose cotransporter 2 inhibitor, were included. Echocardiography was performed at baseline, 30 and 180 days, and analysed by a central core‐lab in a blinded manner to both patient and time. The primary endpoint was the change in maximal LA volume index (LAVI). A total of 162 patients (64.2% men, 70.5 ± 10.6 years, 52% LVEF >40%) were included in the study. At baseline, LA dilatation was observed (LAVI 48.1 ± 22.6 ml/m2) and LA parameters were similar between LVEF‐based phenotypes (≤40% vs. >40%). LAVI showed a significant reduction at 180 days (−6.6% [95% confidence interval −11.1, −1.8], p = 0.008), primarily due to a decrease in reservoir volume (−13.8% [95% confidence interval −22.5, −4], p = 0.007). Left ventricular geometry improved with significant reductions in left ventricular mass index (−13.9% [95% confidence interval −18.7, −8.7], p < 0.001), end‐diastolic volume (−8.0% [95% confidence interval −11.6, −4.2], p < 0.001) and end‐systolic volume (−11.9% [95% confidence interval −16.7, −6.8], p < 0.001) at 180 days. N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) showed a significant reduction at 180 days (−18.2% [95% confidence interval −27.1, −8.2], p < 0.001), without changes in filling Doppler measures. Conclusion: Dapagliflozin administration in stable out‐setting patients with chronic HF and optimized therapy results in global reverse remodelling of cardiac structure, including reductions in LA volumes and improvement in left ventricular geometry and NT‐proBNP concentrations. [ABSTRACT FROM AUTHOR]

Published
2023
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163. Long-term Prognostic Value of a Comprehensive Assessment of Cardiac Magnetic Resonance Indexes After an ST-segment Elevation Myocardial Infarction

Author

Merlos, Pilar, López-Lereu, Maria P., Monmeneu, Jose V., Sanchis, Juan, Núñez, Julio, Bonanad, Clara, Valero, Ernesto, Miñana, Gema, Chaustre, Fabián, Gómez, Cristina, Oltra, Ricardo, Palacios, Lorena, Bosch, Maria J., Navarro, Vicente, Llácer, Angel, Chorro, Francisco J., and Bodí, Vicente

Published
2013
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169. Sacubitril/valsartan affects pulmonary arterial pressure in heart failure with preserved ejection fraction and pulmonary hypertension

Author

Codina, Pau, primary, Domingo, Mar, additional, Barceló, Elena, additional, Gastelurrutia, Paloma, additional, Casquete, Daniel, additional, Vila, Joan, additional, Abdul‐Jawad Altisent, Omar, additional, Spitaleri, Giosafat, additional, Cediel, Germán, additional, Santiago‐Vacas, Evelyn, additional, Zamora, Elisabet, additional, Ruiz‐Cueto, María, additional, Santesmases, Javier, additional, de la Espriella, Rafael, additional, Pascual‐Figal, Domingo A., additional, Nuñez, Julio, additional, Lupón, Josep, additional, and Bayes‐Genis, Antoni, additional

Published
2022
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171. Utility of plasma CA125 as a proxy of intra-abdominal pressure in patients with acute heart failure

Author

Rubio-Gracia, Jorge, primary, Crespo-Aznarez, Silvia, additional, De la Espriella, Rafael, additional, Nuñez, Gonzalo, additional, Sánchez-Marteles, Marta, additional, Garcés-Horna, Vanesa, additional, Yanguas-Barea, Nerea, additional, Josa-Laorden, Claudia, additional, Cobo-Marcos, Marta, additional, Giménez-López, Ignacio, additional, Pérez-Calvo, Juan Ignacio, additional, and Nuñez, Julio, additional

Published
2022
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172. Mortality Risk Prediction Dynamics After Heart Failure Treatment Optimization: Repeat Risk Assessment Using Online Risk Calculators

Author

Codina, Pau, primary, Zamora, Elisabet, additional, Levy, Wayne C., additional, Revuelta-López, Elena, additional, Borrellas, Andrea, additional, Spitaleri, Giosafat, additional, Cediel, Germán, additional, Ruiz-Cueto, María, additional, Cañedo, Elena, additional, Santiago-Vacas, Evelyn, additional, Domingo, Mar, additional, Buchaca, David, additional, Subirana, Isaac, additional, Santesmases, Javier, additional, Espriella, Rafael de la, additional, Nuñez, Julio, additional, Lupón, Josep, additional, and Bayes-Genis, Antoni, additional

Published
2022
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177. Head‐to‐head comparison of contemporary heart failure risk scores

Author

Codina, Pau, Lupón, Josep, Borrellas, Andrea, Spitaleri, Giosafat, Cediel, Germán, Domingo, Mar, Simpson, Joanne, Levy, Wayne C., Santiago‐Vacas, Evelyn, Zamora, Elisabet, Buchaca, David, Subirana, Isaac, Santesmases, Javier, Diez‐Quevedo, Crisanto, Troya, Maria I., Boldo, Maria, Altmir, Salvador, Alonso, Nuria, González, Beatriz, Rivas, Carmen, Nuñez, Julio, McMurray, John, and Bayes‐Genis, Antoni

Abstract

Aims: \ud Several heart failure (HF) web-based risk scores are currently used in clinical practice. Currently, we lack head-to-head comparison of the accuracy of risk scores. This study aimed to assess correlation and mortality prediction performance of Meta-Analysis Global Group in Chronic Heart Failure (MAGGIC-HF) risk score, which includes clinical variables + medications; Seattle Heart Failure Model (SHFM), which includes clinical variables + treatments + analytes; PARADIGM Risk of Events and Death in the Contemporary Treatment of Heart Failure (PREDICT-HF) and Barcelona Bio-Heart Failure (BCN-Bio-HF) risk calculator, which also include biomarkers, like N-terminal pro B-type natriuretic peptide (NT-proBNP).\ud \ud Methods and results: \ud A total of 1166 consecutive patients with HF from different aetiologies that had NT-proBNP measurement at first visit were included. Discrimination for all-cause mortality was compared by Harrell's C-statistic from 1 to 5 years, when possible. Calibration was assessed by calibration plots and Hosmer–Lemeshow test and global performance by Nagelkerke's R2. Correlation between scores was assessed by Spearman rank test. Correlation between the scores was relatively poor (rho value from 0.66 to 0.79). Discrimination analyses showed better results for 1-year mortality than for longer follow-up (SHFM 0.817, MAGGIC-HF 0.801, PREDICT-HF 0.799, BCN-Bio-HF 0.830). MAGGIC-HF showed the best calibration, BCN-Bio-HF overestimated risk while SHFM and PREDICT-HF underestimated it. BCN-Bio-HF provided the best discrimination and overall performance at every time-point.\ud \ud Conclusions: \ud None of the contemporary risk scores examined showed a clear superiority over the rest. BCN-Bio-HF calculator provided the best discrimination and overall performance with overestimation of risk. MAGGIC-HF showed the best calibration, and SHFM and PREDICT-HF tended to underestimate risk. Regular updating and recalibration of online web calculators seems necessary to improve their accuracy as HF management evolves at unprecedented pace.

Published
2021

183. One-Week and 6-Month Cardiovascular Magnetic Resonance Outcome of the Pharmacoinvasive Strategy and Primary Angioplasty for the Reperfusion of ST-Segment Elevation Myocardial Infarction

Author

Bodí, Vicente, Rumiz, Eva, Merlos, Pilar, Nunez, Julio, López-Lereu, Maria P., Monmeneu, José V., Chaustre, Fabián, Moratal, David, Trapero, Isabel, Blasco, Maria L., Oltra, Ricardo, Sanjuán, Rafael, Chorro, Francisco J., Llàcer, Àngel, and Sanchis, Juan

Published
2011
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185. Global Warming, Renal Function and Heart Failure Over 20 Years

Author

Aimo, Alberto, primary, Lupon, Josep, additional, Spitaleri, Giosafat, additional, Domingo, Mar, additional, Codina, Pau, additional, Santiago-Vacas, Evelyin, additional, Cediel, German, additional, Zamora, Elizabet, additional, Troya, Maribel, additional, Santesmases, Javier, additional, Romero-Gonzalez, Gregorio A., additional, Nuñez, Julio, additional, Martini, Nicola, additional, Emdin, Michele, additional, and Bayes-Genis, Antoni, additional

Published
2022
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189. The Sum of ST-Segment Elevation Is the Best Predictor of Microvascular Obstruction in Patients Treated Successfully by Primary Percutaneous Coronary Intervention. Cardiovascular Magnetic Resonance Study

Author

Husser, Oliver, Bodí, Vicente, Sanchis, Juan, Núnez, Julio, Mainar, Luis, Rumiz, Eva, López-Lereu, María Pilar, Monmeneu, José, Chaustre, Fabián, Trapero, Isabel, Forteza, María J., Riegger, Günter A.J., Chorro, Francisco Javier, and Llàcer, Ángel

Published
2010
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192. La suma de la elevación del segmento ST predice mejor la obstrucción microvascular en pacientes tratados con éxito con una intervención coronaria percutánea primaria. Un estudio de resonancia magnética cardiovascular

Author

Husser, Oliver, Bodí, Vicente, Sanchis, Juan, Núnez, Julio, Mainar, Luis, Rumiz, Eva, López-Lereu, María Pilar, Monmeneu, José, Chaustre, Fabián, Trapero, Isabel, Forteza, María J., Riegger, Günter A.J., Chorro, Francisco Javier, and Llàcer, Àngel

Published
2010
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194. Direct Oral Anticoagulants versus Warfarin in Octogenarians with Nonvalvular Atrial Fibrillation: A Systematic Review and Meta-Analysis

Author

Bonanad, Clara, primary, García-Blas, Sergio, additional, Torres Llergo, Javier, additional, Fernández-Olmo, Rosa, additional, Díez-Villanueva, Pablo, additional, Ariza-Solé, Albert, additional, Martínez-Sellés, Manuel, additional, Raposeiras, Sergio, additional, Ayesta, Ana, additional, Bertomeu-González, Vicente, additional, Tarazona Santabalbina, Francisco, additional, Facila, Lorenzo, additional, Vivas, David, additional, Gabaldón-Pérez, Ana, additional, Bodi, Vicente, additional, Nuñez, Julio, additional, and Cordero, Alberto, additional

Published
2021
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