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1,122 results on '"Murdoch, D."'

152. Assessment of Functional Significance of Coronary Artery Disease of Indeterminate Severity with Fractional Flow Reserve in Patients with Aortic Stenosis Undergoing Transcatheter Aortic Valve Implantation

Author

Subban, V., primary, Savage, M., additional, Crowhurst, J., additional, Robinson, B., additional, Poon, K., additional, Incani, A., additional, Gaikwad, N., additional, Murdoch, D., additional, Aroney, C., additional, Raffel, C., additional, Bett, N., additional, and Walters, D., additional

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2016
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154. Author reply

Author

Markham, R., primary, Murdoch, D., additional, Walters, D. L., additional, and Hamilton-Craig, C., additional

Published
2016
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156. Comparative Outcomes of Balloon, Mechanical and Self-expanding Devices in Transcatheter Aortic Valve Replacement

Author

Markham, R., primary, Challa, A., additional, Hlaing, S., additional, Kyranis, S., additional, Murdoch, D., additional, Savage, M., additional, Shaw, E., additional, Gaikwad, N., additional, Hyasat, K., additional, Hanna, J., additional, Latona, J., additional, Mandala, A., additional, Kahrom, A., additional, Walters, D., additional, and He, C., additional

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2016
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161. J-CTO Score in Predicting Procedural Success and Outcomes at 12 Months: A Single Centre Registry

Author

Kahrom, A., primary, Markham, R., additional, Mandala, A., additional, Gaikwad, N., additional, Kyranis, S., additional, Murdoch, D., additional, Savage, M., additional, Crowhurst, J., additional, Rusli, S., additional, Tan, X., additional, Kahrom, N., additional, Shaw, E., additional, Hyasat, K., additional, Challa, A., additional, Walters, D., additional, and He, C., additional

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2016
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164. Impact of Frailty on 30-Day Outcomes in Patients Undergoing Transcatheter Aortic Valve Replacement

Author

Challa, A., primary, Markham, R., additional, Hlaing, S., additional, Kyranis, S., additional, Murdoch, D., additional, Savage, M., additional, Crowhurst, J., additional, Shaw, E., additional, Gaikwad, N., additional, Kahrom, A., additional, Mandala, A., additional, Hyasat, K., additional, Hanna, J., additional, Latona, J., additional, Walters, D., additional, and He, C., additional

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2016
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166. Outcomes After Transcatheter Pulmonary Valve (Melody) Implantation in a Tertiary Australian Centre

Author

Markham, R., primary, Challa, A., additional, Kyranis, S., additional, Mandala, A., additional, Hanna, J., additional, Latona, J., additional, Gluer, R., additional, Mengel, C., additional, Gaikwad, N., additional, Shaw, E., additional, Vaishnav, M., additional, Kahrom, A., additional, Hliang, S., additional, Murdoch, D., additional, Poon, K., additional, Malpas, T., additional, Hamilton-Craig, C., additional, and Walters, D., additional

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2016
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167. Cause of Death and Predictors of All‐Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation: Data From ROCKET AF

Author

Pokorney, Sean D., primary, Piccini, Jonathan P., additional, Stevens, Susanna R., additional, Patel, Manesh R., additional, Pieper, Karen S., additional, Halperin, Jonathan L., additional, Breithardt, Günter, additional, Singer, Daniel E., additional, Hankey, Graeme J., additional, Hacke, Werner, additional, Becker, Richard C., additional, Berkowitz, Scott D., additional, Nessel, Christopher C., additional, Mahaffey, Kenneth W., additional, Fox, Keith A. A., additional, Califf, Robert M., additional, Anderson, J., additional, Bedwell, N., additional, Bilsker, M., additional, Bruce, G., additional, Agah, R., additional, DeSantis, M., additional, Eisenberg, S., additional, Flores, A., additional, Herzog, W., additional, Klein, S., additional, Snyder, H., additional, Krueger, S., additional, Almaguer, E., additional, Lavie, E., additional, Lee, C., additional, Mallis, G., additional, Modi, M., additional, Woodworth, G., additional, Niazi, I., additional, Peart, B., additional, Sundaram, S., additional, Snoddy, B., additional, Sotolongo, R., additional, Moloney, J., additional, Vijayaraghavan, K., additional, Whittier, F., additional, Yellen, L., additional, Banerjee, S., additional, Lustgarten, D., additional, Suresh, D., additional, Gelernt, M., additional, Levinson, L., additional, Ghanekar, R., additional, Kneller, G., additional, Hall, C., additional, Fadl, Y., additional, Pirwitz, M., additional, French, W., additional, Mayer, N., additional, Pugeda, J., additional, Steel, K., additional, Mody, F., additional, Malik, A., additional, Chandna, H., additional, Go, A., additional, Emlein, G., additional, Bowden, W., additional, Moscoso, R., additional, Hodson, R., additional, Berk, M., additional, Pan, D., additional, Pappas, J., additional, Orchard, R., additional, Lynchard, G., additional, Vijay, N., additional, Khan, W., additional, El Khadra, M, additional, Antonishen, M., additional, Cucher, F., additional, Staab, M., additional, Zebrack, J., additional, Borromeo, S, additional, Heilman, J., additional, Chaturvedi, S., additional, Makam, S., additional, Turk, S., additional, Hyers, T., additional, Williams, G., additional, Labroo, A., additional, Gill, S., additional, Myears, D., additional, Weinstein, J., additional, Shanes, J., additional, Chandrashekhar, Y., additional, Shah, S., additional, Reiter, W., additional, Logemann, T., additional, Almquist, A., additional, Bhagwat, R., additional, Tak, T., additional, Shen‐Ling, J., additional, Patel, P., additional, Artis, A., additional, Arouni, A., additional, Lauer, M., additional, Kinney, K., additional, Elsen, J., additional, Roan, P., additional, Villafria, R., additional, Sumpter, M., additional, Ip, J., additional, Welka, S., additional, Schifferdecker, B., additional, Sandoval, R., additional, Speirs, S., additional, Jones, A., additional, Haldis, T., additional, Kazmierski, J., additional, Sutherland, J., additional, Dietrich, D., additional, Telfer, E., additional, Berry, J., additional, McElveen, A., additional, Russell, J., additional, Sackett, M., additional, Antonios, N., additional, Smith, D., additional, Vora, K., additional, Kirby, A., additional, Lui, H., additional, Mego, D., additional, Ziada, K., additional, Navas, J., additional, Taussig, A., additional, Koren, M., additional, Vogel, C., additional, Saba, F., additional, Parrott, C., additional, Schneider, R., additional, Shirwany, A., additional, Rubin, M., additional, Treasure, C, additional, Bertolet, B., additional, Chang, M., additional, Langberg, J., additional, Becker, R., additional, Cohen, Y., additional, McGrew, F., additional, White, J., additional, Arzola, F., additional, Zelenka, J., additional, Tannenbaum, A., additional, Fernandes, V., additional, Jamnadas, P., additional, Agamasu, J., additional, Collins, B., additional, Jauch, W., additional, Sasseen, B., additional, Hotchkiss, D., additional, Abadier, R., additional, Osunkoya, A., additional, Schlau, A., additional, Chappel, C., additional, Foster, M., additional, Braun, E., additional, Mostel, E., additional, Capo, J., additional, Ashchi, M., additional, Howard, V., additional, Albirini, A., additional, Burger, A., additional, Rolston, D., additional, Staniloae, C., additional, Bacon, J., additional, Wiseman, A., additional, McGarvey, J, additional, Sonel, A., additional, Hamroff, G., additional, Chang, D., additional, Daboul, N., additional, Broderick, G., additional, Meholick, A., additional, Corbelli, J., additional, Silverman, R., additional, Raffetto, J., additional, Fishberg, R., additional, Georgeson, S., additional, Held, J., additional, Seidner, M., additional, Saint‐Jacques, H., additional, Heitner, J., additional, Kutalek, S., additional, Friedlander, I., additional, Hutchinson, B., additional, Walia, J., additional, Kondo, N., additional, Smiley, N., additional, Blitz, L., additional, Dale, H., additional, Sulman, S., additional, Szulawski, I., additional, Modares, F., additional, Martin, R., additional, Nahhas, A., additional, Renzi, M., additional, Akyea‐Djamson, A., additional, Alfieri, A., additional, Sandhu, J., additional, Voyce, S., additional, Amaram, S., additional, Meyerrose, G., additional, Shoukfeh, M., additional, Lee, F., additional, Villegas, B., additional, Idowu, O., additional, Khera, A., additional, Sam, C., additional, Vo, A., additional, Lieber, I., additional, Smith, T., additional, Awan, N., additional, Tsai, C., additional, Ganim, R., additional, Alzaghrini, G., additional, Pitt, W., additional, Shepherd, A., additional, Tang, S., additional, Stoltz, S., additional, Nelson, W., additional, Cox, S., additional, Meymandi, S., additional, Melucci, M., additional, Thomas, G., additional, Gogia, H., additional, Machell, C., additional, Chandrasekaran, S., additional, Brown, C., additional, Jetty, P., additional, Miller, G., additional, Dykstra, G., additional, Jaffrani, N., additional, Zakhary, B., additional, Caruso, A., additional, Zolty, R., additional, Fox, D., additional, Jacobs, G., additional, Lebenthal, M., additional, Mukherjee, S., additional, Zimetbaum, P., additional, Kingsley, J., additional, Jones, R., additional, Robinson, V., additional, Kenton, D., additional, Usedom, J., additional, Williams, S., additional, Snipes, C., additional, Wilson, V., additional, Hasty, R., additional, Shoemaker, J., additional, Donahue, M., additional, Al‐Saghir, Y., additional, Thomsen, E., additional, Yarows, S., additional, Chastain, S., additional, McLaughlin, P., additional, Wakham, M., additional, Shrestha, D., additional, Simmons, J., additional, Fisher, D., additional, Seymour, Z., additional, Frandsen, B., additional, First, B., additional, Sharpe, C., additional, Popeil, L., additional, Guthrie, R., additional, Hunter, J., additional, Alvarado, O., additional, Sandberg, J., additional, Gutman, N., additional, Belber, A., additional, Arkhipov, M., additional, Ballyzek, M., additional, Baranov, A., additional, Barbarash, O., additional, Barbarich, V., additional, Belenky, D., additional, Berkovich, O., additional, Bokarev, I., additional, Boyarkin, M., additional, Vaniev, S., additional, Volkova, E., additional, Gratsiansky, N., additional, Demin, A., additional, Zadionchenko, V., additional, Zateyshchikov, D., additional, Zrazhevsky, K., additional, Mazaev, V., additional, Martynov, A., additional, Mikhailov, S., additional, Mkrtchian, V., additional, Novozhenov, V., additional, Raskina, T., additional, Rebrov, A., additional, Sanina, N., additional, Simanekov, V., additional, Sitnikova, M., additional, Smolenskaya, O., additional, Stryuk, R., additional, Storozhakov, G., additional, Tankhilevich, B., additional, Tereschenko, S., additional, Khokhlov, A., additional, Khrustalev, O., additional, Chernov, S., additional, Shvarts, Y., additional, Shubik, Y., additional, Shulman, V., additional, Yakushin, S., additional, Bugrova, O., additional, Ivleva, A., additional, Libis, R., additional, Khozyainova, N., additional, Maslov, S., additional, Baranova, E., additional, Sherenkov, A., additional, Libov, I., additional, Lusov, V., additional, Chumakova, G., additional, Kuznetsov, V., additional, Ryamzina, I., additional, Reshetko, O., additional, Boldueva, S., additional, Alekseeva, N., additional, Novikova, T., additional, Dvornikov, V., additional, Idrisova, E., additional, Shostak, N., additional, Yarokhno, N., additional, Tebloev, K., additional, Treshkur, T., additional, Mazurov, V., additional, Loktin, E., additional, Sedavnyh, I., additional, Alexeeva, O., additional, Yakhontova, P., additional, Repin, A., additional, Izmozherova, N., additional, Kostenko, V., additional, Fokin, A., additional, Ketova, G., additional, Kouz, S., additional, Leader, R., additional, Ayala‐Paredes, F., additional, Luton, R., additional, Ma, P., additional, Pandey, S., additional, Pesant, Y., additional, Senior, R., additional, Vertes, G., additional, Bell, A., additional, Crowley, D., additional, Vizel, S., additional, Lasko, B., additional, Landry, D., additional, Berger, L., additional, Heath, J., additional, Bessoudo, R., additional, Ling, M., additional, Tellier, G., additional, Berlingieri, J., additional, Kafka, H., additional, Hill, L., additional, Mazza, G., additional, O'Mahony, W., additional, Chilvers, M., additional, O'Mahony, M., additional, Newman, D., additional, Silagy, S., additional, Heffernan, M., additional, Bennett, M., additional, Bhesania, T., additional, Rockman, G., additional, Ng, K., additional, Kalra, B., additional, Meneses, G., additional, Liang, W., additional, Cheung, M., additional, Kozak, J., additional, Pugen, G., additional, Vavougios, J., additional, Kates, M., additional, Nunes‐Vaz, C., additional, Jaffer, S., additional, Orfi, J., additional, Faiers, A., additional, Chung, C., additional, Felsen, S., additional, Bergman, S., additional, Bernstein, I., additional, Brownscombe, L., additional, Stockdill, J., additional, Silver, E., additional, Ezekiel, D., additional, Jagan, N., additional, Khurana, M., additional, Reisler, H., additional, Goldman, H., additional, Maung, T., additional, Wong, F., additional, Gillis, G., additional, Vexler, R., additional, Goldberg, B., additional, Luterman, M., additional, Gould, D., additional, Coutu, B., additional, Ouellet, A., additional, MacDonald, P., additional, Jones, M., additional, Collette, R., additional, Chong, P., additional, Fargher, T., additional, St‐Maurice, F., additional, Fortin, C., additional, Chehayeb, R., additional, Proulx, G., additional, Roy, R., additional, Liutkus, J., additional, Syan, G., additional, Rupka, D., additional, Lichtenstein, T., additional, Kooy, J., additional, Papastergiou, D., additional, Lubelsky, B., additional, Doyle, W., additional, Rajakumar, A., additional, Cha, J., additional, Choudhry, A., additional, Bhamjee, H., additional, Mawji, A., additional, Durfresne, M., additional, Constance, C., additional, Mutrie, J., additional, Najarali, A., additional, Warren, R., additional, Mucha, M., additional, Borts, D., additional, Nord, P., additional, Carrier, S., additional, Dawood, M., additional, Sabe‐Affaki, G., additional, Archibald, J., additional, Abram, N., additional, Teitelbaum, E., additional, Ebrahim, I., additional, Siebert, R., additional, van Zyl, L., additional, Theron, H., additional, Lloyd, E., additional, Sommers, R., additional, Podgorski, G., additional, Steingo, L., additional, Dalby, A., additional, Bayat, J., additional, Herbst, L., additional, Bester, F., additional, Corbett, C., additional, Bennett, J., additional, Roodt, A., additional, Roux, J., additional, Abelson, M., additional, Mohamed, Z., additional, Nortje, H., additional, Da Silva, A., additional, Nikolaides, K., additional, Liagkas, K., additional, Papasteriadis, E., additional, Achimastos, A., additional, Koliopoulos, N., additional, Trikas, A., additional, Manolis, A., additional, Ruiter, J., additional, Basart, D., additional, Crijns, H., additional, Withagen, A., additional, Janssen, M., additional, Van Langeveld, R, additional, van Gelder, I., additional, Hamer, B., additional, Van Der Heijden, R, additional, Hertzeberger, D., additional, Van Hessen, M, additional, Pieterse, M., additional, Groutars, R., additional, Kuijper, A., additional, De Ruiter, G, additional, van Boven, A., additional, Hoogslag, P., additional, Kragten, H., additional, Thijssen, H., additional, Veldkamp, R., additional, Scavee, C., additional, Heidbuchel, H., additional, Debruyne, P., additional, Deruyter, B., additional, El Ali, H, additional, Goethals, M., additional, Cytryn, R., additional, Striekwold, H., additional, De Wolf, L, additional, Goethals, P., additional, Provenier, F., additional, Hellemans, S., additional, Galinier, M., additional, Coisne, D., additional, Koenig, A., additional, Galley, D., additional, Destrac, S., additional, Leduc, J., additional, Rifai, A., additional, Citron, B., additional, Ellie, E., additional, Fournier, P., additional, Steg, G., additional, Landel, R., additional, Robinson, A., additional, Ziegler, F., additional, Boulliat, J., additional, Zuber, M., additional, Vida, M., additional, Galve Basilio, E., additional, Lopez, M., additional, Íñiguez, C., additional, Iglesias Alonso, L., additional, Cavero Gibanel, M., additional, Olivan Martinez, J., additional, Calvo Iglesias, F., additional, Marco Vera, P., additional, Bruguera Cortada, J., additional, Jaber Houbani, A., additional, Merino, J., additional, Olaz Preciado, F., additional, Balaguer, J., additional, de la Hera Galarza, J, additional, Martinez Rubio, A., additional, Fontcuberta, J., additional, Sotillo Marti, J., additional, Gonzalez Juanatey, J., additional, Del Campo, R., additional, Vivanco, G., additional, Alvarez Garcia, P., additional, Pelayo, M., additional, Lippai, J., additional, Zamolyi, K., additional, Károly, T., additional, Vertes, A., additional, Nagy, A., additional, Kosa, I., additional, Janosi, A., additional, Lupkovics, G., additional, Kalo, E., additional, Forster, T., additional, Kis, E., additional, Tenczer, J., additional, Bereczki, D., additional, Komoly, S., additional, Csanyi, A., additional, Kiss, R., additional, Valikovics, A., additional, Dioszeghy, P., additional, Masini, F., additional, Terrosu, P., additional, Cirrincione, V., additional, Marabotti, C., additional, Cosmi, F., additional, Salvioni, A., additional, Binetti, G., additional, Piovaccari, G., additional, Nassiacos, D., additional, Boriani, G., additional, Calvi, V., additional, De Caterina, R, additional, Pengo, V., additional, Parati, G., additional, Carolei, A., additional, D'Angelo, A., additional, Di Biase, M., additional, Fattore, L., additional, Agnelli, G., additional, Merlini, P., additional, Furlan, M., additional, Rasura, M., additional, Gandolfo, C., additional, Ageno, W., additional, Piovella, F., additional, Micieli, G., additional, Cinteza, M., additional, Fierbinteanu, C., additional, Natase‐Melicovici, D., additional, Ionescu, D., additional, Macarie, C., additional, Nanea, I., additional, Radoi, M., additional, Tatu‐Chitoiu, G., additional, Dragulescu, S., additional, Tudose, A., additional, Militaru, C., additional, Bengus, C., additional, Ungureanu, G., additional, Tau, A., additional, Popa, V., additional, Pirvu, O., additional, Bojinca, M., additional, Sipciu, D., additional, Popescu, M., additional, Chiru, M., additional, Vinereanu, D., additional, Tudoran, M., additional, Cojocaru, T., additional, Vintila, M., additional, Aron, G., additional, Petrascu, O., additional, Bolohan, F., additional, Baumgartner, R., additional, Sekoranja, L., additional, Vojacek, J., additional, Lacnak, B., additional, Kellnerova, I., additional, Dunaj, M., additional, Cihalik, C., additional, Janota, T., additional, Janousek, J., additional, Bouchal, P., additional, Spacek, R., additional, Choi Siruckova, J., additional, Heinc, P., additional, Vojtisek, P., additional, Pirchala, M., additional, Malecha, J., additional, Padour, F., additional, Linhart, A., additional, Mandysova, E., additional, Jandik, J., additional, Zidkova, E., additional, Sipula, D., additional, Ostadal, P., additional, Polasek, R., additional, Stransky, V., additional, Marcinek, G., additional, Rysava, D., additional, Osmancik, P., additional, Huber, K., additional, Drexel, H., additional, Brainin, M., additional, Eichinger‐Hasenauer, S., additional, Lang, W., additional, Pilger, E., additional, Moriarty, A., additional, Hudson, I., additional, Tang, K., additional, Cleland, J., additional, MacWalter, R., additional, Cooke, J., additional, McInnes, G., additional, Durairaj, R., additional, MacLeod, M., additional, Murdoch, D., additional, Kadr, H., additional, Lip, G., additional, Andrews, R., additional, Hunt, B., additional, Jackson, P., additional, Roffe, C., additional, Syed, H., additional, Bath, P., additional, Coyle, J., additional, Kelly, D., additional, Stender, S., additional, TorpPedersen, C., additional, Tuxen, C., additional, Jensen, G., additional, Melchior, T., additional, Klarlund, K., additional, Dahlstrom, C., additional, Nielsen, T., additional, Nielsen, E., additional, Bronnum‐Schou, J., additional, Sykulski, R., additional, Blomstrom, P., additional, Lindholm, C., additional, Wallen, T., additional, Nilsson, C., additional, Bertholds, E., additional, Carlsater, J., additional, Sirnes, P., additional, Elle, S., additional, Risberg, K., additional, Furuseth, K., additional, Skag, A., additional, Hoivik, H., additional, Landmark, N., additional, Kjaernli, T., additional, Berg‐Johansen, J., additional, Gradek, G., additional, Drzewiecki, A., additional, Pluta, W., additional, Szwed, H., additional, Trusz‐Gluza, M., additional, Ogorek, M., additional, Loboz‐Grudzien, K., additional, Ruszkowski, P., additional, Sciborski, R., additional, Kopaczewski, J., additional, Jaworska, K., additional, Kubica, J., additional, Opolski, G., additional, Hoffman, A., additional, Krzciuk, M., additional, Sinkiewicz, W., additional, Piotrowski, W., additional, Kolodziej, P., additional, Goszczynska, M., additional, Rynkiewicz, A., additional, Chojnowska, L., additional, Lewczuk, J., additional, Biedrzycka, M., additional, Piepiorka, M., additional, Kowal, J., additional, Karczmarczyk, A., additional, Pruszczyk, P., additional, Tendera, M., additional, Gaciong, Z., additional, Krzeminska‐Pakula, M., additional, Kornacewicz‐Jach, Z., additional, Kania, G., additional, Brachmann, J., additional, Lawall, H., additional, Guelker, H., additional, Spitzer, S., additional, MoebiusWinkler, S., additional, Dempfle, C., additional, Bode, C., additional, Darius, H., additional, Genth‐Zotz, S., additional, Sommer, S., additional, Roehnisch, J., additional, Strasser, R., additional, Daenschel, W., additional, Schwencke, C., additional, vom Dahl, J, additional, Meuser, M., additional, Behrens‐Spandau, S., additional, Behrens‐Humbold, S., additional, Muegge, A., additional, Schoen, N., additional, Grooterhorst, P., additional, Ebert, H., additional, Kraemer, A., additional, Kohler, B., additional, Taggeselle, J., additional, Claus, G., additional, Sarnighausen, H., additional, Al‐Zoebi, A., additional, Schroeder, T., additional, Weissbrodt, M., additional, Lange, R., additional, Gabelmann, M., additional, Kaeaeb, S., additional, Doerr, M., additional, Boscher, D., additional, Bosch, R., additional, Sonntag, F., additional, Bauknecht, C., additional, Omran, H., additional, Leicht, M., additional, Veltkamp, R., additional, Hohensee, H., additional, Dieckmann, H., additional, Winkelmann, B., additional, Bernhardt, P., additional, Schnabel, A., additional, Kadel, C., additional, Proskynitopoulos, N., additional, Seidl, K., additional, Schellong, S., additional, Rios, C., additional, Guevara, C., additional, Coloma, R., additional, Torrejon, H., additional, Parra Galvan, J., additional, Drago Silva, J., additional, Gallegos, J., additional, Mendoza, A., additional, Negron, S., additional, Watanabe, L., additional, Medina, F., additional, Virgen Carrilo, L., additional, Alvarez Lopez, H., additional, Rodriguez, I., additional, Leiva‐Pons, J., additional, Baños Velasco, A., additional, Villarreal‐Careaga, J., additional, De los Rios, M, additional, Gamba, M., additional, Llamas Esperon, G., additional, Villeda, E., additional, Ahuad Guerrero, A., additional, Alvariqueta, A., additional, Amuchastegui, M., additional, Bluguermann, J., additional, Caime, G., additional, Cuneo, C., additional, Gabito, A., additional, Garcia Brasca, D., additional, Hominal, M., additional, Jure, H., additional, Luquez, H., additional, Montana, O., additional, Piskorz, D., additional, Listorti, S., additional, Serra, J., additional, Sessa, H., additional, Varini, S., additional, Vita, N., additional, Aiub, J., additional, MacKinnon, I., additional, Chekherdemian, S., additional, Castagnino, J., additional, Cimbaro Canella, J., additional, Sgammini, H., additional, Escudero, A., additional, Albina, G., additional, Rapallo, C., additional, Balparda, C., additional, Chahin, M., additional, Fuentealba, V., additional, Riccitelli, M., additional, Casabe, J., additional, Lobo Marquez, L., additional, Kevorkian, R., additional, Cuadrado, J., additional, Dran, R., additional, Muntaner, J., additional, Gonzalez, M., additional, Cartasegna, L., additional, Hasbani, E., additional, Hrabar, A., additional, Sanchez, A., additional, Vogel, D., additional, Hershson, A., additional, Avezum, A., additional, Jaber, J., additional, Ernesto Leaes, P., additional, Bozza, A., additional, Lorga Filho, A., additional, Pimentel Filho, P., additional, Moura Jorge, J., additional, Maia, L., additional, Manenti, E., additional, D'Aurea Mora, R, additional, de Souza Neto, J, additional, Precoma, D., additional, Rabelo, A., additional, Rocha, J., additional, Rossi, P., additional, Kerr Saraiva, J., additional, Zimerman, L., additional, Bodanese, L., additional, Figueiredo, E., additional, de Souza, W. Sebba Barroso, additional, Braga, J., additional, Alessi, S., additional, Gomes, M., additional, Silva, R., additional, Teixeira, M., additional, Costa, F., additional, Motta, M., additional, Sobral Filho, D., additional, Reis, G., additional, Garbelini, B, additional, Zimmermann, S., additional, Pereira Barretto, A., additional, Dohmann, H., additional, Barreto Filho, J., additional, Ghorayeb, N., additional, Borelli, F., additional, Rossi dos Santos, F., additional, Lopes Prudente, M., additional, Vejar, M., additional, Lanas, F., additional, Del Pino, R., additional, Potthoff, S., additional, Charme, G., additional, Aguirre, A., additional, Saldana, A., additional, Garces, E., additional, Bunster, L., additional, Figueroa, H., additional, Olivares, C., additional, Raffo, C., additional, Vergara, E., additional, Sepulveda, P., additional, Jano, G., additional, Morales Alvarado, J., additional, Suarez, R., additional, Urina, M., additional, Perez, G., additional, Quintero, A., additional, Pava, L., additional, Botero Lopez, R., additional, Luengas, C., additional, Hernandez, E., additional, Sanchez, D., additional, Poveda, C., additional, Coronel, J., additional, Beltran, R., additional, Jaramillo, C., additional, Pardo, J., additional, Ponte Negretti, C., additional, Isea, J., additional, Vergara, G., additional, Morr, I., additional, Sim, K., additional, Wan Ahmad, W., additional, Yusof, Z., additional, Rosman, A., additional, Basri, H, additional, Thompson, P., additional, Jeffery, I., additional, Purnell, P., additional, Roberts‐Thomson, P., additional, Heddle, W., additional, Waites, J., additional, Walters, D., additional, Amerena, J., additional, Challa, P., additional, Karrasch, J., additional, Lowy, A., additional, Fitzpatrick, D., additional, Parsons, M., additional, Phan, T., additional, Bladin, C., additional, Donnan, G., additional, Aroney, G., additional, Gerraty, R., additional, Anderson, C., additional, Blombery, P., additional, Martin, P., additional, Tissa Wijeratne, K., additional, Cross, D., additional, Crimmins, D., additional, Packham, D., additional, Jackson, D., additional, Chua, W., additional, Merino, R., additional, Magno, M., additional, Tirador, L., additional, Batalla, E., additional, Manalo, C., additional, Uy, N., additional, Ebo, G., additional, Reyes, E., additional, Bernan, A., additional, Richards, M., additional, Hart, H., additional, Mann, S., additional, Fisher, R., additional, Stewart, R., additional, Wilkins, G., additional, Barber, A., additional, Tan, R., additional, Ong, H., additional, Singh, R., additional, Sukonthasarn, A., additional, Tanomsup, S., additional, Krittayaphong, R., additional, Piamsomboon, C., additional, Piyayotai, D., additional, Sunsaneewitayakul, B., additional, Baek, S., additional, Seo, H., additional, Rim, S., additional, Kim, C., additional, Kim, K., additional, Ryu, K., additional, Jo, S., additional, Tahk, S., additional, Lee, H., additional, Kim, Y., additional, Shin, D., additional, Choi, Y., additional, Chung, N., additional, Namgung, J., additional, Hong, T., additional, Shin, W., additional, Jin, S., additional, Yan, X., additional, Fu, G., additional, Lu, G., additional, Yang, K., additional, Xu, D., additional, Chen, J., additional, Liu, J., additional, Wu, S., additional, Song, J., additional, Liao, Y., additional, Xu, B., additional, Li, Z., additional, Ma, S., additional, Yin, Y., additional, Zhao, Y., additional, Hu, D., additional, Ma, C., additional, Ma, J., additional, Sun, J., additional, Li, H., additional, Hong, X., additional, Yu, B., additional, Lu, Q., additional, Yang, J., additional, Wu, Z., additional, Li, Y., additional, Huang, Y., additional, Wang, Y., additional, Liu, M., additional, Cheng, Y., additional, Yang, T., additional, Chen, K., additional, Wang, H., additional, Yuan, Z., additional, Wang, J., additional, Zeng, Z., additional, Chen, Y., additional, Yavuzgil, O., additional, Kozan, O., additional, Etemoglu, M., additional, Diker, E., additional, Belgi, A., additional, Ceyhan, C., additional, Cin, V., additional, Yilmaz, O., additional, Ata, N., additional, Altunkeser, B., additional, Agacdiken Agir, A., additional, Karadede, A., additional, Topsakal, R., additional, Gulati, R., additional, Madhavan, A., additional, Jain, S., additional, Oomman, A., additional, Janorkar, S., additional, Kumar, P., additional, Madhukar Naik, A., additional, Thacker, H., additional, Rajasekhar, V., additional, Reddy, R., additional, Keshavamurthy, C., additional, Jain, P., additional, Gowdappa, B., additional, Gadkari, M., additional, Abhyankar, A., additional, Ramesh Babu, B., additional, Vydianathan, P., additional, Sinha, S., additional, Garg, N., additional, Rao, S., additional, Gautam, P., additional, Chockalingam, K., additional, Kumbla, M., additional, Panwar, R., additional, Banker, D., additional, Kaste, M., additional, Jäkälä, P., additional, Roine, R., additional, Mihov, A., additional, Raev, D., additional, Yordanova, V., additional, Dimitrova, S., additional, Benov, H., additional, Tsanova, V., additional, Kyolean, M., additional, Marchev, S., additional, Stoikov, A., additional, Zdravkov, N., additional, Ramshev, K., additional, Krastev, A., additional, Stamenova, P., additional, Angelova, I., additional, Pencheva, G., additional, Grigorova, V., additional, Petrauskiene, B., additional, Skripkauskiene, I., additional, Raugaliene, R., additional, Norkiene, S., additional, Mazutavicius, R., additional, Kavoliuniene, A., additional, Aidietiene, S., additional, Aganauskiene, J., additional, Dailydkiene, A., additional, Marcinkeviciene, J., additional, Grigoniene, L., additional, Anusauskiene, J., additional, Kavaliauskiene, R., additional, Lizogub, V., additional, Rudenko, L., additional, Tseluyko, V., additional, Voronkov, L., additional, Sychov, O., additional, Svyshchenko, Y., additional, Sirenko, Y., additional, Serkova, V., additional, Seredyuk, N., additional, Pertseva, T., additional, Netyazhenko, V., additional, Lishnevska, V., additional, Kupchynska, O., additional, Koval, O., additional, Koshukova, G., additional, Karpenko, O., additional, Grishyna, O., additional, Faynyk, A., additional, Dzyak, G., additional, Dyadyk, O., additional, Yena, L., additional, Volkov, V., additional, Rudyk, I., additional, Kopytsya, M., additional, Kononenko, L., additional, Amosova, K., additional, Zhurba, S., additional, Kazimirko, V., additional, Iuzkiv, I., additional, Shershnyova, O., additional, Khomazyuk, T., additional, Batushkin, V., additional, Vykhovanyuk, I., additional, Popik, G., additional, Skrebkov, V., additional, Skurtov, A., additional, Mishchenko, T., additional, Lytvynenko, N., additional, Sokolova, L., additional, Vatutin, M., additional, Shved, M., additional, Rebrov, B., additional, Kadina, L., additional, Vajda, M., additional, Ursol, G., additional, Zheleznyy, V., additional, Vysochanska, T., additional, Gozhenko, A., additional, Fan, K., additional, Ho, D., additional, Tse, H., additional, Yu, C., additional, Wong, L., additional, Yeh, H., additional, Pai, P., additional, Hsieh, I., additional, Huang, C., additional, Hsieh, Y., additional, Yin, W., additional, Tsai, L., additional, Huang, T., additional, Chen, C., additional, Chiang, F., additional, Ueng, K., additional, Charng, M., additional, Marmor, A., additional, Katz, A., additional, Butnaru, A., additional, Lewis, B., additional, Eldar, M., additional, Rosenhack, S., additional, Elias, N., additional, Koifman, B., additional, Shochat, M., additional, Swissa, M., additional, Zimlichman, R., additional, Bental, T., additional, Weiss, A., additional, Ganam, R., additional, Elias, M., additional, Nseir, W., additional, Oliven, A., additional, Brenner, B., additional, and Dayan, M., additional

Published
2016
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171. What do infectious diseases physicians do? A 2-week snapshot of inpatient consultative activities across Australia, New Zealand and Singapore.

Author

Holland D., Sowden D., Everts R., Lee L.-y., Wolfgang J., Day T., Silva G.D., Martinello M., Gliddon T., Wilson M., Athan E., Pollard J., Harris P., Pachchigar R., Wehrhahn M., Moriarty P., Langlands A., McBride S., Sherif M., Lim K., Choong K., Henderson A., Manon M., Sud A., Read K., Yap R., Bursle E., Gluer R., Siebert D., Cross G., Francis J., Booth C., Dalton S., Ooi E.L., Chih D., Dyer J., Clarke J., Grimwood K., Gwee A., Commons R., Majumdar S., Warren S., Manners D., Raby E., Radhakrishnan D., Keighley C., Dotel R., Paterson D., Best E., Aung A.K., Paterson T., Hassell M., Newcombe J., Llorin R., Lye D., Giola M., Yew H.S., Taylor J., Iredell J., Pollett S., Garg L., Jennings Z., Kapur A., Miyakis S., Parshuramkar D., Thu K.M., Rasiah K., Bak N., Chen S., Cooley L., Gordon D., Howden B., McBryde E., Murdoch D., Peleg A., Ralph A., Robinson O., Slavin M., Sorrell T., Tong S., Woolley I., Ingram P.R., Murray R.J., Cheng A.C., Blyth C.C., Walls T., Fisher D.A., Davis J.S., Abbott I., Kanapathipillai R., Madigan V., McLellan D., Briggs S., King C., Hurley J., Lim L.-L., Kennedy K., Wilson H., Evans T., Maze M., Pithie A., Chong L., Leung G., McCann S., Holland D., Sowden D., Everts R., Lee L.-y., Wolfgang J., Day T., Silva G.D., Martinello M., Gliddon T., Wilson M., Athan E., Pollard J., Harris P., Pachchigar R., Wehrhahn M., Moriarty P., Langlands A., McBride S., Sherif M., Lim K., Choong K., Henderson A., Manon M., Sud A., Read K., Yap R., Bursle E., Gluer R., Siebert D., Cross G., Francis J., Booth C., Dalton S., Ooi E.L., Chih D., Dyer J., Clarke J., Grimwood K., Gwee A., Commons R., Majumdar S., Warren S., Manners D., Raby E., Radhakrishnan D., Keighley C., Dotel R., Paterson D., Best E., Aung A.K., Paterson T., Hassell M., Newcombe J., Llorin R., Lye D., Giola M., Yew H.S., Taylor J., Iredell J., Pollett S., Garg L., Jennings Z., Kapur A., Miyakis S., Parshuramkar D., Thu K.M., Rasiah K., Bak N., Chen S., Cooley L., Gordon D., Howden B., McBryde E., Murdoch D., Peleg A., Ralph A., Robinson O., Slavin M., Sorrell T., Tong S., Woolley I., Ingram P.R., Murray R.J., Cheng A.C., Blyth C.C., Walls T., Fisher D.A., Davis J.S., Abbott I., Kanapathipillai R., Madigan V., McLellan D., Briggs S., King C., Hurley J., Lim L.-L., Kennedy K., Wilson H., Evans T., Maze M., Pithie A., Chong L., Leung G., and McCann S.

Abstract

The practice of an infectious diseases (ID) physician is evolving. A contemporary understanding of the frequency and variety of patients and syndromes seen by ID services has implications for training, service development and setting research priorities. We performed a 2-week prospective survey of formal ID physician activities related to direct inpatient care, encompassing 53 hospitals throughout Australia, New Zealand and Singapore, and documented 1722 inpatient interactions. Infections involving the skin and soft tissue, respiratory tract and bone/joints together accounted for 49% of all consultations. Suspected/confirmed pathogens were primarily bacterial (60%), rather than viral (6%), fungal (4%), mycobacterial (2%) or parasitic (1%). Staphylococcus aureus was implicated in 409 (24%) episodes, approximately four times more frequently than the next most common pathogen. The frequency of healthcare-related infections (35%), immunosuppression (21%), diabetes mellitus (19%), prosthesis-related infections (13%), multiresistant pathogens (13%) and non-infectious diagnoses (9%) was high, although consultation characteristics varied between geographical settings and hospital types. Our study highlights the diversity of inpatient-related ID activities and should direct future teaching and research. ID physicians' ability to offer beneficial consultative advice requires broad understanding of, and ability to interact with, a wide range of referring specialities.Copyright © 2014 European Society of Clinical Microbiology and Infectious Diseases.

Published
2015

172. Impact of early valve surgery on outcome of Staphylococcus aureus prosthetic valve infective endocarditis: analysis in the International Collaboration of Endocarditis-Prospective Cohort Study

Author

Chirouze, C., Alla, F., Fowler, V. G., Sexton, D. J., Corey, G. R., Chu, V. H., Wang, A., Erpelding, M-L., Durante-Mangoni, E., Fernández-Hidalgo, N., Giannitsioti, E., Hannan, M. M., Lejko-Zupanc, T., Miró, J. M., Muñoz, P., Murdoch, D. R., Tattevin, P., Tribouilloy, C., Hoen, B., Athan, E., Chirouze, C., Alla, F., Fowler, V. G., Sexton, D. J., Corey, G. R., Chu, V. H., Wang, A., Erpelding, M-L., Durante-Mangoni, E., Fernández-Hidalgo, N., Giannitsioti, E., Hannan, M. M., Lejko-Zupanc, T., Miró, J. M., Muñoz, P., Murdoch, D. R., Tattevin, P., Tribouilloy, C., Hoen, B., and Athan, E.

Abstract

BACKGROUND: The impact of early valve surgery (EVS) on the outcome of Staphylococcus aureus (SA) prosthetic valve infective endocarditis (PVIE) is unresolved. The objective of this study was to evaluate the association between EVS, performed within the first 60 days of hospitalization, and outcome of SA PVIE within the International Collaboration on Endocarditis-Prospective Cohort Study. METHODS: Participants were enrolled between June 2000 and December 2006. Cox proportional hazards modeling that included surgery as a time-dependent covariate and propensity adjustment for likelihood to receive cardiac surgery was used to evaluate the impact of EVS and 1-year all-cause mortality on patients with definite left-sided S. aureus PVIE and no history of injection drug use. RESULTS: EVS was performed in 74 of the 168 (44.3%) patients. One-year mortality was significantly higher among patients with S. aureus PVIE than in patients with non-S. aureus PVIE (48.2% vs 32.9%; P = .003). Staphylococcus aureus PVIE patients who underwent EVS had a significantly lower 1-year mortality rate (33.8% vs 59.1%; P = .001). In multivariate, propensity-adjusted models, EVS was not associated with 1-year mortality (risk ratio, 0.67 [95% confidence interval, .39-1.15]; P = .15). CONCLUSIONS: In this prospective, multinational cohort of patients with S. aureus PVIE, EVS was not associated with reduced 1-year mortality. The decision to pursue EVS should be individualized for each patient, based upon infection-specific characteristics rather than solely upon the microbiology of the infection causing PVIE.

Published
2015

173. Infective endocarditis due to group D Streptococci in the international Collaboration on Endocarditis prospective cohort study

Author

Chirouze C, Cabell C, Pappas P, Bernard Y, Tripodi MF, Olaison L, Bradley S, Doco Lecompte T, Murdoch D, Habib G, Plesiat P, Leroy J, Woods C, Miro J, Corey R, Hoen B., UTILI, Riccardo, Chirouze, C, Utili, Riccardo, Cabell, C, Pappas, P, Bernard, Y, Tripodi, Mf, Olaison, L, Bradley, S, Doco Lecompte, T, Murdoch, D, Habib, G, Plesiat, P, Leroy, J, Woods, C, Miro, J, Corey, R, and Hoen, B.

Published
2004

177. Low serum cortisol predicts early death following acute myocardial infarction

Author

Reynolds, R.M., Walker, B.R., Haw, S., Newby, D.E., Mackay, D.F., Cobbe, S.M., Pell, A.C.H., Fischbacher, C.M., Pringle, S., Murdoch, D., Dunn, F., Oldroyd, K., MacIntyre, P., O’Rourke, B., and Pell, J.

Subjects
RC
Abstract

Objective: Low serum cortisol concentrations have been associated with adverse prognosis in critical illness of diverse aetiology. We aimed to determine whether low serum cortisol concentrations are associated with adverse prognosis in patients with acute myocardial infarction. \ud \ud Design: Nested case-control study.\ud \ud Setting: Prospective cohort study of consecutive patients admitted with acute myocardial infarction to 9 Scottish hospitals. \ud \ud Patients: 100 patients who survived 30 days (controls) and 100 patients who died within 30 days (cases). \ud \ud Measurements and Main Results: Admission cortisol concentrations were lower in patients who died than those who survived (median 1,189 versus 1,355 nmol/L, pConclusions: Patients who mount a lesser cortisol stress response to acute myocardial infarction have a poorer early prognosis.

Published
2010

192. Programmable active pixel sensor to investigate neural interactions within the retina

Author

Hart, M.D., Prydderch, M.L., Morrison, J.D., Murdoch, D., and Mathieson, K.

Subjects
genetic structures, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, RE, sense organs, eye diseases, ComputingMethodologies_COMPUTERGRAPHICS
Abstract

Detection of the visual scene by the eye and the resultant neural interactions of the retina-brain system give us our perception of sight. We have developed an Active Pixel Sensor (APS) to be used as a tool for both furthering understanding of these interactions via experimentation with the retina and to make developments towards a realisable retinal prosthesis. The sensor consists of 469 pixels in a hexagonal array. The pixels are interconnected by a programmable neural network to mimic lateral interactions between retinal cells. Outputs from the sensor are in the form of biphasic current pulse trains suitable to stimulate retinal cells via a biocompatible array. The APS will be described with initial characterisation and test results.

Published
2009

193. Validity of self-reported smoking status: comparison of patients admitted to hospital with acute coronary syndrome and the general population

Author

Pell, J., Haw, S.J., Cobbe, S.M., Newby, D.E., Pell, A.C.H., Oldroyd, K.G., Murdoch, D., Pringle, S.D., Dunn, F.G., MacIntyre, P.D., Gilbert, T.J., Fischbacher, C.M., and Borland, W.

Subjects
RA0421, RA
Abstract

Many studies rely on self-reported smoking status. We hypothesized that patients with acute coronary syndrome (ACS), a smoking-related condition, would be more prone to misclassify themselves as ex-smokers, because of pressure to quit. We compared patients admitted with ACS with a general population survey conducted in the same country at a similar time. We determined whether ACS patients who classified themselves as ex-smokers (n = 635) were more likely to have cotinine levels suggestive of smoking deception than self-reported ex-smokers in the general population (n = 289). On univariate analysis, the percentage of smoking deceivers was similar among ACS patients and the general population (11% vs. 12%, p = .530). Following adjustment for age, sex and exposure to environmental tobacco smoke, ACS patients were significantly more likely to misclassify themselves (adjusted OR = 14.06, 95% CI 2.13-93.01, p = .006). There was an interaction with age whereby the probability of misclassification fell significantly with increasing age in the ACS group (adjusted OR = 0.95, 95% CI 0.93-0.97, p

Published
2008

195. RISKS FOR INFECTIVE ENDOCARDITIS (IE) IN THE ELDERLY. LESSONS FROM THE INTERNATIONAL COLLABORATION ON ENDOCARDITIS PROSPECTIVE COHORT STUDY (ICE-PCS)

Author

Utili R, Bradley S, Tripodi M-F, Durante Mangoni E, Bouza E, Moreno A, Pappas P, Baršić B, Francis CK, Ramos R, van der Meer JT, Tattevin P, Murdoch D, Fowler V, Abrutyn E, Miro JM, Sexton DJ, Cabell C, for the ICE Investigators

Subjects
endokarditis, starije osobe
Abstract

Background. It is assumed that IE is more common in older adults, however no data regarding risk factors for IE are available from large prospective studies. Methods To delineate risk factors for IE in aged individuals we analyzed data from 1779 consecutive IE cases prospectively enrolled in the ICE-PCS. Patients >64 (n=689) were compared with patients 64 p

Published
2005

196. Reply to Boethel et al

Author

Murdoch, D. R., primary, Podmore, R. G., additional, Anderson, T. P., additional, Barratt, K., additional, Maze, M. J., additional, French, K. E., additional, Young, S. A., additional, Chambers, S. T., additional, and Werno, A. M., additional

Published
2014
Full Text
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199. HACEK Infective Endocarditis: Characteristics and Outcomes from a Large, Multi-National Cohort.

Author

Revest M., Kirill O., Vadim K., Vinogradova T., Edathodu J., Halim M., Lum L.-N., Tan R.-S., Lejko-Zupanc T., Logar M., Mueller-Premru M., Commerford P., Commerford A., Deetlefs E., Hansa C., Ntsekhe M., Almela M., Armero Y., Azqueta M., Castan~eda X., Cervera C., Rio A., Falces C., Garcia-de-la-Maria C., Fita G., Gatell J.M., Marco F., Mestres C.A., Miro J.M., Moreno A., Ninot S., Pare C., Pericas J., Ramirez J., Rovira I., Sitges M., Anguera I., Font B., Guma J.R., Bermejo J., Fernandez M.A.G., Gonzalez-Ramallo V., Marin M., Mun~oz P., Pedromingo M., Roda J., Rodriguez-Creixems M., Solis J., Almirante B., Fernandez-Hidalgo N., Tornos P., de Alarcon A., Parra R., Alestig E., Johansson M., Snygg-Martin U., Pachirat O., Pachirat P., Pussadhamma B., Senthong V., Casey A., Elliott T., Lambert P., Watkin R., Eyton C., Klein J.L., Bradley S., Kauffman C., Bedimo R., Crowley A.L., Douglas P., Drew L., Fowler V.G., Holland T., Lalani T., Mudrick D., Samad Z., Sexton D., Stryjewski M., Woods C.W., Lerakis S., Cantey R., Steed L., Wray D., Dickerman S.A., Bonilla H., DiPersio J., Salstrom S.-J., Baddley J., Patel M., Peterson G., Stancoven A., Afonso L., Kulman T., Levine D., Rybak M., Baloch K., Corey G.R., Dixon C.C., Fowler Jr. V.G., Harding T., Jones-Richmond M., Pappas P., Park L.P., Redick T., Stafford J., Anstrom K., Chu V.H., Karchmer A.W., Murdoch D.R., Sexton D.J., Wang A., Bayer A.S., Cabell C.H., Chu V., Durack D.T., Eykyn S., Hoen B., Moreillon P., Olaison L., Raoult D., Rubinstein E., Chambers S.T., Murdoch D., Bouza E., Hannan M.M., Kanafani Z.A., Lang S., Clara L., Sanchez M., Nacinovich F., Oses P.F., Ronderos R., Sucari A., Thierer J., Casabe J., Cortes C., Altclas J., Silvia Kogan S., Spelman D., Athan E., Harris O., Kennedy K., Tan R., Gordon D., Papanicolas L., Eisen D., Grigg L., Street A., Korman T., Kotsanas D., Dever R., Konecny P., Lawrence R., Rees D., Feneley M.P., Harkness J., Jones P., Post J., Reinbott P., Ryan S., Gattringer R., Wiesbauer F., Andrade A.R., de Brito A.C.P., Guimara~es A.C., Grinberg M., Mansur A.J., Siciliano R.F., Strabelli T.M.V., Vieira M.L.C., de Medeiros Tranchesi R.A., Paiva M.G., Fortes C.Q., de Oliveira Ramos A., Ferraiuoli G., Golebiovski W., Lamas C., Santos M., Weksler C., Karlowsky J.A., Keynan Y., Morris A.M., Jones S.B., Garcia P., Cereceda M., Fica A., Mella R.M., Barsic B., Bukovski S., Krajinovic V., Pangercic A., Rudez I., Vincelj J., Freiberger T., Pol J., Zaloudikova B., Ashour Z., Kholy A.E., Mishaal M., Rizk H., Aissa N., Alauzet C., Alla F., Campagnac C., Doco-Lecompte T., Selton-Suty C., Casalta J.-P., Fournier P.-E., Habib G., Thuny F., Delahaye F., Delahaye A., Vandenesch F., Donal E., Donnio P.Y., Michelet C., Sharma G., Tattevin P., Violette J., Chevalier F., Jeu A., Rusinaru D.M.D., Sorel C., Tribouilloy C., Bernard Y., Chirouze C., Leroy J., Plesiat P., Naber C., Mazaheri B., Neuerburg C., Athanasia S., Giannitsioti E., Mylona E., Paniara O., Papanicolaou K., Pyros J., Skoutelis A., Francis J., Nair L., Thomas V., Venugopal K., Hannan M., Hurley J., Gilon D., Israel S., Korem M., Strahilevitz J., Tripodi M.F., Casillo R., Cuccurullo S., Dialetto G., Durante-Mangoni E., Irene M., Ragone E., Utili R., Cecchi E., De Rosa F., Forno D., Imazio M., Trinchero R., Tebini A., Grossi P., Lattanzio M., Toniolo A., Goglio A., Raglio A., Ravasio V., Rizzi M., Suter F., Carosi G., Magri S., Signorini L., Baban T., Kanafani Z., Kanj S.S., Sfeir J., Yasmine M., Abidin I., Tamin S.S., Martinez E.R., Nieto G.I.S., van der Meer J.T.M., Chambers S., Holland D., Morris A., Raymond N., Read K., Dragulescu S., Ionac A., Mornos C., Butkevich O.M., Chipigina N., Revest M., Kirill O., Vadim K., Vinogradova T., Edathodu J., Halim M., Lum L.-N., Tan R.-S., Lejko-Zupanc T., Logar M., Mueller-Premru M., Commerford P., Commerford A., Deetlefs E., Hansa C., Ntsekhe M., Almela M., Armero Y., Azqueta M., Castan~eda X., Cervera C., Rio A., Falces C., Garcia-de-la-Maria C., Fita G., Gatell J.M., Marco F., Mestres C.A., Miro J.M., Moreno A., Ninot S., Pare C., Pericas J., Ramirez J., Rovira I., Sitges M., Anguera I., Font B., Guma J.R., Bermejo J., Fernandez M.A.G., Gonzalez-Ramallo V., Marin M., Mun~oz P., Pedromingo M., Roda J., Rodriguez-Creixems M., Solis J., Almirante B., Fernandez-Hidalgo N., Tornos P., de Alarcon A., Parra R., Alestig E., Johansson M., Snygg-Martin U., Pachirat O., Pachirat P., Pussadhamma B., Senthong V., Casey A., Elliott T., Lambert P., Watkin R., Eyton C., Klein J.L., Bradley S., Kauffman C., Bedimo R., Crowley A.L., Douglas P., Drew L., Fowler V.G., Holland T., Lalani T., Mudrick D., Samad Z., Sexton D., Stryjewski M., Woods C.W., Lerakis S., Cantey R., Steed L., Wray D., Dickerman S.A., Bonilla H., DiPersio J., Salstrom S.-J., Baddley J., Patel M., Peterson G., Stancoven A., Afonso L., Kulman T., Levine D., Rybak M., Baloch K., Corey G.R., Dixon C.C., Fowler Jr. V.G., Harding T., Jones-Richmond M., Pappas P., Park L.P., Redick T., Stafford J., Anstrom K., Chu V.H., Karchmer A.W., Murdoch D.R., Sexton D.J., Wang A., Bayer A.S., Cabell C.H., Chu V., Durack D.T., Eykyn S., Hoen B., Moreillon P., Olaison L., Raoult D., Rubinstein E., Chambers S.T., Murdoch D., Bouza E., Hannan M.M., Kanafani Z.A., Lang S., Clara L., Sanchez M., Nacinovich F., Oses P.F., Ronderos R., Sucari A., Thierer J., Casabe J., Cortes C., Altclas J., Silvia Kogan S., Spelman D., Athan E., Harris O., Kennedy K., Tan R., Gordon D., Papanicolas L., Eisen D., Grigg L., Street A., Korman T., Kotsanas D., Dever R., Konecny P., Lawrence R., Rees D., Feneley M.P., Harkness J., Jones P., Post J., Reinbott P., Ryan S., Gattringer R., Wiesbauer F., Andrade A.R., de Brito A.C.P., Guimara~es A.C., Grinberg M., Mansur A.J., Siciliano R.F., Strabelli T.M.V., Vieira M.L.C., de Medeiros Tranchesi R.A., Paiva M.G., Fortes C.Q., de Oliveira Ramos A., Ferraiuoli G., Golebiovski W., Lamas C., Santos M., Weksler C., Karlowsky J.A., Keynan Y., Morris A.M., Jones S.B., Garcia P., Cereceda M., Fica A., Mella R.M., Barsic B., Bukovski S., Krajinovic V., Pangercic A., Rudez I., Vincelj J., Freiberger T., Pol J., Zaloudikova B., Ashour Z., Kholy A.E., Mishaal M., Rizk H., Aissa N., Alauzet C., Alla F., Campagnac C., Doco-Lecompte T., Selton-Suty C., Casalta J.-P., Fournier P.-E., Habib G., Thuny F., Delahaye F., Delahaye A., Vandenesch F., Donal E., Donnio P.Y., Michelet C., Sharma G., Tattevin P., Violette J., Chevalier F., Jeu A., Rusinaru D.M.D., Sorel C., Tribouilloy C., Bernard Y., Chirouze C., Leroy J., Plesiat P., Naber C., Mazaheri B., Neuerburg C., Athanasia S., Giannitsioti E., Mylona E., Paniara O., Papanicolaou K., Pyros J., Skoutelis A., Francis J., Nair L., Thomas V., Venugopal K., Hannan M., Hurley J., Gilon D., Israel S., Korem M., Strahilevitz J., Tripodi M.F., Casillo R., Cuccurullo S., Dialetto G., Durante-Mangoni E., Irene M., Ragone E., Utili R., Cecchi E., De Rosa F., Forno D., Imazio M., Trinchero R., Tebini A., Grossi P., Lattanzio M., Toniolo A., Goglio A., Raglio A., Ravasio V., Rizzi M., Suter F., Carosi G., Magri S., Signorini L., Baban T., Kanafani Z., Kanj S.S., Sfeir J., Yasmine M., Abidin I., Tamin S.S., Martinez E.R., Nieto G.I.S., van der Meer J.T.M., Chambers S., Holland D., Morris A., Raymond N., Read K., Dragulescu S., Ionac A., Mornos C., Butkevich O.M., and Chipigina N.

Abstract

The HACEK organisms (Haemophilus species, Aggregatibacter species, Cardiobacterium hominis, Eikenella corrodens, and Kingella species) are rare causes of infective endocarditis (IE). The objective of this study is to describe the clinical characteristics and outcomes of patients with HACEK endocarditis (HE) in a large multi-national cohort. Patients hospitalized with definite or possible infective endocarditis by the International Collaboration on Endocarditis Prospective Cohort Study in 64 hospitals from 28 countries were included and characteristics of HE patients compared with IE due to other pathogens. Of 5591 patients enrolled, 77 (1.4%) had HE. HE was associated with a younger age (47 vs. 61 years; p<0.001), a higher prevalence of immunologic/vascular manifestations (32% vs. 20%; p<0.008) and stroke (25% vs. 17% p = 0.05) but a lower prevalence of congestive heart failure (15% vs. 30%; p = 0.004), death in-hospital (4% vs. 18%; p = 0.001) or after 1 year follow-up (6% vs. 20%; p = 0.01) than IE due to other pathogens (n = 5514). On multivariable analysis, stroke was associated with mitral valve vegetations (OR 3.60; CI 1.34-9.65; p<0.01) and younger age (OR 0.62; CI 0.49-0.90; p<0.01). The overall outcome of HE was excellent with the in-hospital mortality (4%) significantly better than for non-HE (18%; p<0.001). Prosthetic valve endocarditis was more common in HE (35%) than non-HE (24%). The outcome of prosthetic valve and native valve HE was excellent whether treated medically or with surgery. Current treatment is very successful for the management of both native valve prosthetic valve HE but further studies are needed to determine why HE has a predilection for younger people and to cause stroke. The small number of patients and observational design limit inferences on treatment strategies. Self selection of study sites limits epidemiological inferences. © 2013 Chambers et al.

Published
2013

200. HACEK Infective Endocarditis: Characteristics and Outcomes from a Large, Multi-National Cohort

Author

Abbate, A, Chambers, ST, Murdoch, D, Morris, A, Holland, D, Pappas, P, Almela, M, Fernandez-Hidalgo, N, Almirante, B, Bouza, E, Forno, D, del Rio, A, Hannan, MM, Harkness, J, Kanafani, ZA, Lalani, T, Lang, S, Raymond, N, Read, K, Vinogradova, T, Woods, CW, Wray, D, Corey, GR, Chu, VH, Clara, L, Sanchez, M, Nacinovich, F, Fernandez Oses, P, Ronderos, R, Sucari, A, Thierer, J, Casabe, J, Cortes, C, Altclas, J, Kogan, S, Spelman, D, Athan, E, Harris, O, Kennedy, K, Tan, R, Gordon, D, Papanicolas, L, Eisen, D, Grigg, L, Street, A, Korman, T, Kotsanas, D, Dever, R, Jones, P, Konecny, P, Lawrence, R, Rees, D, Ryan, S, Feneley, MP, Post, J, Reinbott, P, Gattringer, R, Wiesbauer, F, Andrade, AR, Passos de Brito, AC, Guimaraes, AC, Grinberg, M, Mansur, AJ, Siciliano, RF, Varejao Strabelli, TM, Campos Vieira, ML, de Medeiros Tranchesi, RA, Paiva, MG, Fortes, CQ, Ramos, ADO, Ferraiuoli, G, Golebiovski, W, Lamas, C, Santos, M, Weksler, C, Karlowsky, JA, Keynan, Y, Morris, AM, Rubinstein, E, Jones, SB, Garcia, P, Cereceda, M, Fica, A, Mella, RM, Barsic, B, Bukovski, S, Krajinovic, V, Pangercic, A, Rudez, I, Vincelj, J, Freiberger, T, Pol, J, Zaloudikova, B, Ashour, Z, El Kholy, A, Mishaal, M, Rizk, H, Aissa, N, Alauzet, C, Alla, F, Campagnac, C, Doco-Lecompte, T, Selton-Suty, C, Casalta, J-P, Fournier, P-E, Habib, G, Raoult, D, Thuny, F, Delahaye, F, Delahaye, A, Vandenesch, F, Donal, E, Donnio, PY, Michelet, C, Revest, M, Tattevin, P, Violette, J, Chevalier, F, Jeu, A, Dan, Rusinaru, Sorel, C, Tribouilloy, C, Bernard, Y, Chirouze, C, Hoen, B, Leroy, J, Plesiat, P, Naber, C, Neuerburg, C, Mazaheri, B, Athanasia, S, Giannitsioti, E, Mylona, E, Paniara, O, Papanicolaou, K, Pyros, J, Skoutelis, A, Sharma, G, Francis, J, Nair, L, Thomas, V, Venugopal, K, Hannan, M, Hurley, J, Gilon, D, Israel, S, Korem, M, Strahilevitz, J, Tripodi, MF, Casillo, R, Cuccurullo, S, Dialetto, G, Durante-Mangoni, E, Irene, M, Ragone, E, Utili, R, Cecchi, E, De Rosa, F, Imazio, M, Trinchero, R, Tebini, A, Grossi, P, Lattanzio, M, Toniolo, A, Goglio, A, Raglio, A, Ravasio, V, Rizzi, M, Suter, F, Carosi, G, Magri, S, Signorini, L, Baban, T, Kanafani, Z, Kanj, SS, Sfeir, J, Yasmine, M, Abidin, I, Tamin, SS, Martinez, ER, Nieto, GIS, van der Meer, JTM, Chambers, S, Murdoch, DR, Dragulescu, S, Ionac, A, Mornos, C, Butkevich, OM, Chipigina, N, Kirill, O, Vadim, K, Edathodu, J, Halim, M, Lum, L-N, Tan, R-S, Lejko-Zupanc, T, Logar, M, Mueller-Premru, M, Commerford, P, Commerford, A, Deetlefs, E, Hansa, C, Ntsekhe, M, Armero, Y, Azqueta, M, Castaneda, X, Cervera, C, Falces, C, Garcia-de-la-Maria, C, Fita, G, Gatell, JM, Marco, F, Mestres, CA, Miro, JM, Moreno, A, Ninot, S, Pare, C, Pericas, J, Ramirez, J, Rovira, I, Sitges, M, Anguera, I, Font, B, Guma, JR, Bermejo, J, Garcia Fernandez, MA, Gonzalez-Ramallo, V, Marin, M, Munoz, P, Pedromingo, M, Roda, J, Rodriguez-Creixems, M, Solis, J, Tornos, P, de Alarcon, A, Parra, R, Alestig, E, Johansson, M, Olaison, L, Snygg-Martin, U, Pachirat, O, Pachirat, P, Pussadhamma, B, Senthong, V, Casey, A, Elliott, T, Lambert, P, Watkin, R, Eyton, C, Klein, JL, Bradley, S, Kauffman, C, Bedimo, R, Crowley, AL, Douglas, P, Drew, L, Fowler, VG, Holland, T, Mudrick, D, Samad, Z, Sexton, D, Stryjewski, M, Wang, A, Lerakis, S, Cantey, R, Steed, L, Dickerman, SA, Bonilla, H, DiPersio, J, Salstrom, S-J, Baddley, J, Patel, M, Peterson, G, Stancoven, A, Afonso, L, Kulman, T, Levine, D, Rybak, M, Cabell, CH, Baloch, K, Dixon, CC, Harding, T, Jones-Richmond, M, Park, LP, Redick, T, Stafford, J, Anstrom, K, Bayer, AS, Karchmer, AW, Sexton, DJ, Chu, V, Durack, DT, Phil, D, Eykyn, S, Moreillon, P, Abbate, A, Chambers, ST, Murdoch, D, Morris, A, Holland, D, Pappas, P, Almela, M, Fernandez-Hidalgo, N, Almirante, B, Bouza, E, Forno, D, del Rio, A, Hannan, MM, Harkness, J, Kanafani, ZA, Lalani, T, Lang, S, Raymond, N, Read, K, Vinogradova, T, Woods, CW, Wray, D, Corey, GR, Chu, VH, Clara, L, Sanchez, M, Nacinovich, F, Fernandez Oses, P, Ronderos, R, Sucari, A, Thierer, J, Casabe, J, Cortes, C, Altclas, J, Kogan, S, Spelman, D, Athan, E, Harris, O, Kennedy, K, Tan, R, Gordon, D, Papanicolas, L, Eisen, D, Grigg, L, Street, A, Korman, T, Kotsanas, D, Dever, R, Jones, P, Konecny, P, Lawrence, R, Rees, D, Ryan, S, Feneley, MP, Post, J, Reinbott, P, Gattringer, R, Wiesbauer, F, Andrade, AR, Passos de Brito, AC, Guimaraes, AC, Grinberg, M, Mansur, AJ, Siciliano, RF, Varejao Strabelli, TM, Campos Vieira, ML, de Medeiros Tranchesi, RA, Paiva, MG, Fortes, CQ, Ramos, ADO, Ferraiuoli, G, Golebiovski, W, Lamas, C, Santos, M, Weksler, C, Karlowsky, JA, Keynan, Y, Morris, AM, Rubinstein, E, Jones, SB, Garcia, P, Cereceda, M, Fica, A, Mella, RM, Barsic, B, Bukovski, S, Krajinovic, V, Pangercic, A, Rudez, I, Vincelj, J, Freiberger, T, Pol, J, Zaloudikova, B, Ashour, Z, El Kholy, A, Mishaal, M, Rizk, H, Aissa, N, Alauzet, C, Alla, F, Campagnac, C, Doco-Lecompte, T, Selton-Suty, C, Casalta, J-P, Fournier, P-E, Habib, G, Raoult, D, Thuny, F, Delahaye, F, Delahaye, A, Vandenesch, F, Donal, E, Donnio, PY, Michelet, C, Revest, M, Tattevin, P, Violette, J, Chevalier, F, Jeu, A, Dan, Rusinaru, Sorel, C, Tribouilloy, C, Bernard, Y, Chirouze, C, Hoen, B, Leroy, J, Plesiat, P, Naber, C, Neuerburg, C, Mazaheri, B, Athanasia, S, Giannitsioti, E, Mylona, E, Paniara, O, Papanicolaou, K, Pyros, J, Skoutelis, A, Sharma, G, Francis, J, Nair, L, Thomas, V, Venugopal, K, Hannan, M, Hurley, J, Gilon, D, Israel, S, Korem, M, Strahilevitz, J, Tripodi, MF, Casillo, R, Cuccurullo, S, Dialetto, G, Durante-Mangoni, E, Irene, M, Ragone, E, Utili, R, Cecchi, E, De Rosa, F, Imazio, M, Trinchero, R, Tebini, A, Grossi, P, Lattanzio, M, Toniolo, A, Goglio, A, Raglio, A, Ravasio, V, Rizzi, M, Suter, F, Carosi, G, Magri, S, Signorini, L, Baban, T, Kanafani, Z, Kanj, SS, Sfeir, J, Yasmine, M, Abidin, I, Tamin, SS, Martinez, ER, Nieto, GIS, van der Meer, JTM, Chambers, S, Murdoch, DR, Dragulescu, S, Ionac, A, Mornos, C, Butkevich, OM, Chipigina, N, Kirill, O, Vadim, K, Edathodu, J, Halim, M, Lum, L-N, Tan, R-S, Lejko-Zupanc, T, Logar, M, Mueller-Premru, M, Commerford, P, Commerford, A, Deetlefs, E, Hansa, C, Ntsekhe, M, Armero, Y, Azqueta, M, Castaneda, X, Cervera, C, Falces, C, Garcia-de-la-Maria, C, Fita, G, Gatell, JM, Marco, F, Mestres, CA, Miro, JM, Moreno, A, Ninot, S, Pare, C, Pericas, J, Ramirez, J, Rovira, I, Sitges, M, Anguera, I, Font, B, Guma, JR, Bermejo, J, Garcia Fernandez, MA, Gonzalez-Ramallo, V, Marin, M, Munoz, P, Pedromingo, M, Roda, J, Rodriguez-Creixems, M, Solis, J, Tornos, P, de Alarcon, A, Parra, R, Alestig, E, Johansson, M, Olaison, L, Snygg-Martin, U, Pachirat, O, Pachirat, P, Pussadhamma, B, Senthong, V, Casey, A, Elliott, T, Lambert, P, Watkin, R, Eyton, C, Klein, JL, Bradley, S, Kauffman, C, Bedimo, R, Crowley, AL, Douglas, P, Drew, L, Fowler, VG, Holland, T, Mudrick, D, Samad, Z, Sexton, D, Stryjewski, M, Wang, A, Lerakis, S, Cantey, R, Steed, L, Dickerman, SA, Bonilla, H, DiPersio, J, Salstrom, S-J, Baddley, J, Patel, M, Peterson, G, Stancoven, A, Afonso, L, Kulman, T, Levine, D, Rybak, M, Cabell, CH, Baloch, K, Dixon, CC, Harding, T, Jones-Richmond, M, Park, LP, Redick, T, Stafford, J, Anstrom, K, Bayer, AS, Karchmer, AW, Sexton, DJ, Chu, V, Durack, DT, Phil, D, Eykyn, S, and Moreillon, P

Abstract

The HACEK organisms (Haemophilus species, Aggregatibacter species, Cardiobacterium hominis, Eikenella corrodens, and Kingella species) are rare causes of infective endocarditis (IE). The objective of this study is to describe the clinical characteristics and outcomes of patients with HACEK endocarditis (HE) in a large multi-national cohort. Patients hospitalized with definite or possible infective endocarditis by the International Collaboration on Endocarditis Prospective Cohort Study in 64 hospitals from 28 countries were included and characteristics of HE patients compared with IE due to other pathogens. Of 5591 patients enrolled, 77 (1.4%) had HE. HE was associated with a younger age (47 vs. 61 years; p<0.001), a higher prevalence of immunologic/vascular manifestations (32% vs. 20%; p<0.008) and stroke (25% vs. 17% p = 0.05) but a lower prevalence of congestive heart failure (15% vs. 30%; p = 0.004), death in-hospital (4% vs. 18%; p = 0.001) or after 1 year follow-up (6% vs. 20%; p = 0.01) than IE due to other pathogens (n = 5514). On multivariable analysis, stroke was associated with mitral valve vegetations (OR 3.60; CI 1.34-9.65; p<0.01) and younger age (OR 0.62; CI 0.49-0.90; p<0.01). The overall outcome of HE was excellent with the in-hospital mortality (4%) significantly better than for non-HE (18%; p<0.001). Prosthetic valve endocarditis was more common in HE (35%) than non-HE (24%). The outcome of prosthetic valve and native valve HE was excellent whether treated medically or with surgery. Current treatment is very successful for the management of both native valve prosthetic valve HE but further studies are needed to determine why HE has a predilection for younger people and to cause stroke. The small number of patients and observational design limit inferences on treatment strategies. Self selection of study sites limits epidemiological inferences.

Published
2013

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