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152. Physical performance of biodegradable films intended for antimicrobial food packaging

Author

Marcos Muntal, Begonya, Aymerich Calvet, Mª Teresa, Monfort, J. M., Garriga Turón, Margarita, and IRTA. Recerca i Tecnologia Agroalimentàries

Subjects
Seguretat alimentària, Aliments -- Envasament, food and beverages, 663/664 - Aliments i nutrició. Enologia. Olis. Greixos
Abstract

Antimicrobial films were prepared by including enterocins to alginate, polyvinyl alcohol (PVOH), and zein films. The physical performance of the films was assessed by measuring color, microstructure (SEM), water vapor permeability (WVP), and tensile properties. All studied biopolymers showed poor WVP and limited tensile properties. PVOH showed the best performance exhibiting the lowest WVP values, higher tensile properties, and flexibility among studied biopolymers. SEM of antimicrobial films showed increased presence of voids and pores as a consequence of enterocin addition. However, changes in microstructure did not disturb WVP of films. Moreover, enterocin-containing films showed slight improvement compared to control films. Addition of enterocins to PVOH films had a plasticizing effect, by reducing its tensile strength and increasing the strain at break. The presence of enterocins had an important effect on tensile properties of zein films by significantly reducing its brittleness. Addition of enterocins, thus, proved not to disturb the physical performance of studied biopolymers. Development of new antimicrobial biodegradable packaging materials may contribute to improving food safety while reducing environmental impact derived from packaging waste.

Published
2010

153. The contribution of sensory system functional connectivity reduction to clinical pain in fibromyalgia

Author

Pujol, J, Macia, D, Garcia-Fontanals, A, Blanco-Hinojo, L, Lopez-Sola, M, Garcia-Blanco, S, Poca-Dias, V, Harrison, BJ, Contreras-Rodriguez, O, Monfort, J, Garcia-Fructuoso, F, Deus, J, Pujol, J, Macia, D, Garcia-Fontanals, A, Blanco-Hinojo, L, Lopez-Sola, M, Garcia-Blanco, S, Poca-Dias, V, Harrison, BJ, Contreras-Rodriguez, O, Monfort, J, Garcia-Fructuoso, F, and Deus, J

Abstract

Fibromyalgia typically presents with spontaneous body pain with no apparent cause and is considered pathophysiologically to be a functional disorder of somatosensory processing. We have investigated potential associations between the degree of self-reported clinical pain and resting-state brain functional connectivity at different levels of putative somatosensory integration. Resting-state functional magnetic resonance imaging was obtained in 40 women with fibromyalgia and 36 control subjects. A combination of functional connectivity-based measurements were used to assess (1) the basic pain signal modulation system at the level of the periaqueductal gray (PAG); (2) the sensory cortex with an emphasis on the parietal operculum/secondary somatosensory cortex (SII); and (3) the connectivity of these regions with the self-referential "default mode" network. Compared with control subjects, a reduction of functional connectivity was identified across the 3 levels of neural processing, each showing a significant and complementary correlation with the degree of clinical pain. Specifically, self-reported pain in fibromyalgia patients correlated with (1) reduced connectivity between PAG and anterior insula; (2) reduced connectivity between SII and primary somatosensory, visual, and auditory cortices; and (3) increased connectivity between SII and the default mode network. The results confirm previous research demonstrating abnormal functional connectivity in fibromyalgia and show that alterations at different levels of sensory processing may contribute to account for clinical pain. Importantly, reduced functional connectivity extended beyond the somatosensory domain and implicated visual and auditory sensory modalities. Overall, this study suggests that a general weakening of sensory integration underlies clinical pain in fibromyalgia.

Published
2014

155. Combined effect of natural antimicrobials and high pressure processing to prevent Listeria monocytogenes growth after a cold chain break during storage of cooked ham

Author

Marcos Muntal, Begonya, Jofré Fradera, Anna, Aymerich Calvet, Mª Teresa, Monfort, J. M., Garriga Turón, Margarita, and IRTA. Recerca i Tecnologia Agroalimentàries

Subjects
Pernil -- Microbiologia
Abstract

The effect of high pressure processing (400 MPa for 10 min) and natural antimicrobials 2 (enterocins and lactate-diacetate) on the behaviour of L. monocytogenes in sliced cooked ham 3 during refrigerated storage (1ºC and 6ºC) was assessed. The efficiency of the treatments after a 4 cold chain break was evaluated. Lactate-diacetate exerted a bacteriostatic effect against L. 5 monocytogenes during the whole storage period (3 months) at 1ºC and 6ºC, even after 6 temperature abuse. The combination of low storage temperature (1ºC), high pressure 7 processing (HPP) and addition of lactate-diacetate reduced the levels of L. monocytogenes 8 during storage by 2.7 log CFU/g. The most effective treatment was the combination of HPP, 9 enterocins and refrigeration at 1ºC, which reduced the population of the pathogen to final counts 10 of 4 MPN/g after 3 months of storage, even after the cold chain break.

Published
2008

156. High-pressure processing and antimicrobial biodegradable packaging to control Listeria monocytogenes during storage of cooked ham

Author

Marcos Muntal, Begonya, Aymerich Calvet, Mª Teresa, Monfort, J. M., Garriga Turón, Margarita, and IRTA. Recerca i Tecnologia Agroalimentàries

Subjects
Aliments -- Microbiologia, Pernil -- Envasament
Abstract

The efficiency of combining high-pressure processing (HPP) and active packaging technologies to control Listeria monocytogenes growth during the shelf life of artificially inoculated cooked ham was assessed. Three lots of cooked ham were prepared: control, packaging with alginate films, and packaging with antimicrobial alginate films containing enterocins. After packaging, half of the samples were pressurized. Sliced cooked ham stored at 6 °C experienced a quick growth of L. monocytogenes. Both antimicrobial packaging and pressurization delayed the growth of the pathogen. However, at 6 °C the combination of antimicrobial packaging and HPP was necessary to achieve a reduction of inoculated levels without recovery during 60 days of storage. Further storage at 6 °C of pressurized antimicrobial packed cooked ham resulted in L. monocytogenes levels below the detection limit (day 90). On the other hand, storage at 1 °C controlled the growth of the pathogen until day 39 in non-pressurized ham, while antimicrobial packaging and storage at 1 °C exerted a bacteriostatic effect for 60 days. All HPP lots stored at 1 °C led to counts

Published
2008

157. Use of antimicrobial biodegradable packaging to control Listeria monocytogenes during storage of cooked ham

Author

Marcos Muntal, Begonya, Aymerich Calvet, Mª Teresa, Monfort, J. M., Garriga Turón, Margarita, and IRTA. Recerca i Tecnologia Agroalimentàries

Subjects
Aliments -- Microbiologia, food and beverages, Pernil -- Envasament
Abstract

The antimicrobial effect against L. monocytogenes of biodegradable films (alginate, zein and polyvinyl alcohol) containing enterocins was investigated. Survival of the pathogen was studied by means of challenge tests performed at 6 °C during 8 and 29 days, for air-packed and vacuum-packed sliced cooked ham, respectively. Air packaging was tested with two concentrations of enterocins (200 and 2000 AU/cm2). Control air-packed cooked ham showed an increase of L. monocytogenes from 104 to 107 CFU/g after 8 days. By contrast, packaging with antimicrobial films effectively slowed down the pathogen's growth, leading to final counts lower than in control lots. Air-packaging with alginate films containing 2000 AU/cm2 of enterocins effectively controlled L. monocytogenes for 8 days. An increase of only 1 log unit was observed in zein and polyvinyl alcohol lots at the same enterocin concentration. Vacuum packaging with films containing enterocins (2000 AU/cm2) also delayed the growth of the pathogen. No increase from inoculated levels was observed during 15 days in antimicrobial alginate films. After 29 days of storage, the lowest counts were obtained in samples packed with zein and alginate films containing enterocins, as well as with zein control films. The most effective treatment for controlling L. monocytogenes during 6 °C storage was vacuum-packaging of sliced cooked ham with alginate films containing 2000 AU/cm2 of enterocins. From the results obtained it can concluded that antimicrobial packaging can improve the safety of sliced cooked ham by delaying and reducing the growth of L. monocytogenes.

Published
2007

158. OP0057 Effects of Chondroitin Sulfate on Brain Response to Painful Stimulation in Knee Osteoarthritis Patients

Author

Monfort, J., primary, Pujol, J., additional, Contreras-Rodríguez, O., additional, Llorente-Onaindia, J., additional, Lόpez-Solà, M., additional, Blanco-Hinojo, L., additional, Deus, J., additional, Ortiz, H., additional, Montañés, F.J., additional, Campillo, M., additional, Benito, P., additional, Sánchez, L., additional, Herrero, M., additional, and Vergés, J., additional

Published
2014
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160. SAT0427 Multicentric Osteoarthritis Intervention Study with Sysadoa (MOVES): Effects of Combined Glucosamine Hydrochloride and Chondroitin Sulfate VS Celecoxib for Painful Knee Osteoarthritis

Author

Hochberg, M., primary, Martel-Pelletier, J., additional, Monfort, J., additional, Möller, I., additional, Castillo, J.-R., additional, Arden, N., additional, Berenbaum, F., additional, Conaghan, P., additional, Pap, T., additional, Richette, P., additional, Sawitzke, A., additional, du Souich, P., additional, and Pelletier, J.-P., additional

Published
2014
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163. Study of the effect of chondroitin sulfate on pain in knee osteoarthritis patients assessed by functional MRI: a randomized, double blind, placebo-controlled clinical trial

Author

Monfort, J., primary, Pujol, J., additional, Contreras-Rodríguez, O., additional, Llorente-Onaindia, J., additional, López-Solà, M., additional, Blanco-Hinojo, L., additional, Deus, J., additional, Ortiz, H., additional, Montañés, F., additional, Campillo, M., additional, Sánchez, L., additional, Herrero, M., additional, Vergés, J., additional, and Benito, P., additional

Published
2014
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164. Lymphoprolifération cutanée primitive CD30+ sous fingolimod : un cas et revue systématique de la littérature

Author

Cesbron, E., Monfort, J.-B., Giannesini, C., Duriez, P., Moguelet, P., Senet, P., Francès, C., Barbaud, A., and Chasset, F.

Abstract

Le fingolimod est un traitement immunomodulateur oral, indiqué dans la sclérose en plaques (SEP) de forme récurrente-rémittente. Nous rapportons un cas de lymphoprolifération cutanée primitive CD30+ survenue sous ce traitement. Nous avons également réalisé une revue systématique des cas publiés dans la littérature médicale, afin de préciser les caractéristiques des lymphoproliférations associées à ce traitement.

Published
2018
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165. Individual Burden of Psoriasis (I-BOP): Building and Validation of a New Scoring Tool for Patients with Psoriasis

Author

Ezzedine K, Fougerousse AC, Aubert R, Monfort JB, Reguiaï Z, Shourick J, Taieb C, and Maccari F

Subjects
disease burden, psoriasis, quality of life, questionnaire, standardized method, Dermatology, RL1-803
Abstract

Khaled Ezzedine, 1 Anne Claire Fougerousse, 2, 3 Roberte Aubert, 4 Jean-Benoît Monfort, 5 Ziad Reguiaï, 3, 6 Jason Shourick, 7 Charles Taieb, 8, 9,* François Maccari 3, 10,* 1Private Pratice, La Varenne Saint Hilaire, France; 2Hôpital d’instruction des armées, Saint-Mandé, France; 3Resopso, Paris, France; 4France Psoriasis, Association de Patients, Paris, France; 5Hôpital Cochin, Paris, France; 6Service de Dermatologie, Polyclinique Courlancy-Bezannes, Reims, France; 7Université Paris Sud, Paris, France; 8Santé Publique, Hôpital Necker Enfants Malades, Paris, France; 9European Market Maintenance Assessment, Fontenay-sous-Bois, France; 10EA EpiDermE UPEC-Université Paris-Est Créteil, Creteil, France*These authors contributed equally to this workCorrespondence: Charles Taieb Tel +33 771 772 100Email charles.taieb@emma.clinicBackground: Psoriasis impacts independently of its severity on patients’ lifestyle and quality of life (QoL).Aim: To build a tool for assessing the patient-reported psoriasis burden.Methods: An expert group created a questionnaire using a standardized methodology building questionnaires assessing quality of life issues. The questionnaire was translated from French into a cultural and linguistically validated US English version.Results: A conceptual questionnaire of 54 questions was created. The confirmatory analyses resulted in a 10-feature questionnaire divided into 4 internally consistent domains with a Cronbach’s alpha coefficient of 0.9. It was reproducible and highly reliable. It correlated well with the Dermatology Life Quality Index (DLQI), Perceived Stress Scale (PSS), and SF-12 mental and SF12 physical scores.Conclusion: This tool allows for the first time to assess the burden of psoriasis patients. Its use may allow improving medical and nonmedical patient care, thus improving their daily life.Keywords: disease burden, psoriasis, quality of life, questionnaire, standardized method

Published
2020

166. Acoustic research for telecoms: bridging the heritage to the future

Author

Nicol Rozenn and Monfort Jean-Yves

Subjects
telecommunication, spatial audio (wavefield synthesis – wfs, higher order ambisonics – hoa, binaural), quality of experience, electroencephalogram (eeg), automatic sound recognition, Acoustics in engineering. Acoustical engineering, TA365-367, Acoustics. Sound, QC221-246
Abstract

In its early age, telecommunication was focused on voice communications, and acoustics was at the heart of the work related to speech coding and transmission, automatic speech recognition or speech synthesis, aiming at offering better quality (Quality of Experience or QoE) and enhanced services to users. As technology has evolved, the research themes have diversified, but acoustics remains essential. This paper gives an overview of the evolution of acoustic research for telecommunication. Communication was initially (and for a long time) only audio with a monophonic narrow-band sound (i.e. [300–3400 Hz]). After the bandwidth extension (from the wide-band [100–7000 Hz] to the full-band [20 Hz–20 kHz] range), a new break was the introduction of 3D sound, either to provide telepresence in audioconferencing or videoconferencing, or to enhance the QoE of contents such as radio, television, VOD, or video games. Loudspeaker or microphone arrays have been deployed to implement “Holophonic” or “Ambisonic” systems. The interaction between spatialized sounds and 3D images was also investigated. At the end of the 2000s, smartphones invaded our lives. Binaural sound was immediately acknowledged as the most suitable technology for reproducing 3D audio on smartphones. However, to achieve a satisfactory QoE, binaural filters need to be customized in relation with the listener’s morphology. This question is the main obstacle to a mass-market distribution of binaural sound, and its solving has prompted a large amount of work. In parallel with the development of technologies, their perceptual evaluation was an equally important area of research. In addition to conventional methods, innovative approaches have been explored for the assessment of sound spatialization, such as physiological measurement, neuroscience tools or Virtual Reality (VR). The latest development is the use of acoustics as a universal sensor for the Internet of Things (IoT) and connected environments. Microphones can be deployed, preferably with parcimony, in order to monitor surrounding sounds, with the goal of detecting information or events thanks to models of automatic sound recognition based on neural networks. Applications range from security and personal assistance to acoustic measurement of biodiversity. As for the control of environments or objects, voice commands have become widespread in recent years thanks to the tremendous progress made in speech recognition, but an even more intuitive mode based on direct control by the mind is proposed by Brain Computer Interfaces (BCIs), which rely on sensory stimulation using different modalities, among which the auditory one offers some advantages.

Published
2023
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172. Panniculite neutrophilique induite par le vemurafenib

Author

Monfort, J.-B., primary, Pagès, C., additional, Schneider, P., additional, Neyns, B., additional, Comte, C., additional, Bagot, M., additional, Mourah, S., additional, Vignon-Pennamen, M.-D., additional, Viguier, M., additional, and Lebbé, C., additional

Published
2012
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180. Combined chondroitin sulfate and glucosamine is more efficient than celebrex in reducing serum levels of Coll2-1, a cartilage degradation biomarker, in patients with severe OA: Results from a randomized, double-blind, multicentric clinical trial

Author

Henrotin, Y., Arden, N., Berenbaum, F., Blanco, F.J., Castillo, J.R., Conaghan, P.G., Hick, A.C., Hochberg, M.C., Martel-Pelletier, J., Monfort, J., Möller, I., Pap, T., Pelletier, J.-P., Richette, P., Sawitzke, A.D., and du Souich, P.

Published
2015
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186. High-attitude low-speed static aerodynamic characteristics of an F-4D fighter airplane model with leading edge slats

Author

Monfort, J. C and Whitcomb, W. M

Subjects
Aircraft Design, Testing And Performance
Abstract

An investigation was conducted to determine the effects of two-position leading edge slats on the low speed aerodynamic characteristics of a swept wing twin-jet supersonic fighter airplane model at high angle of attack and various Reynolds numbers. The investigation was performed at a Mach number of 0.20 over a range of angle of attack from 19 deg to 90 deg and angles of slideslip from -10 deg to 30 deg and Reynolds numbers from 1.97 to 13.12 million per meter.

Published
1975

187. 548 A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED CLINICAL TRIAL ON THE EFFECTS OF CHONDROITIN SULPHATE IN PATIENTS WITH KNEE OSTEOARTHRITIS AND PSORIASIS

Author

Möller, I., primary, Pérez, M., additional, Monfort, J., additional, Benito, P., additional, Cuevas, J., additional, Perna, C., additional, Coll, M., additional, Dalmau, J., additional, Ferran, M., additional, Gilaberte, M., additional, Martí, N., additional, Moragues, C., additional, Roé, E., additional, Segalés, N., additional, Herrero, M., additional, Montell, E., additional, and Vergés, J., additional

Published
2008
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