151. Herpes zoster ophthalmicus in patients at risk for the acquired immune deficiency syndrome (AIDS).
- Author
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Sandor EV, Millman A, Croxson TS, and Mildvan D
- Subjects
- Aged, Female, Homosexuality, Humans, Immunoglobulins analysis, Leukocyte Count, Male, Middle Aged, Prospective Studies, Risk, T-Lymphocytes, Acquired Immunodeficiency Syndrome complications, Herpes Zoster Ophthalmicus complications
- Abstract
In a prospective investigation of 54 consecutive cases of herpes zoster ophthalmicus, conducted over a two-year period, immunologic evaluations included enumeration of T lymphocyte subsets and serum immunoglobulin levels. Herpes zoster ophthalmicus occurred with frequent ocular complications in a subgroup of adults distinguishable by their young age, the presence of AIDS-risk factors, alterations in T-cell subpopulations, and polyclonal increases of serum gammaglobulin. Over the study duration, 21% (three of 14) of the AIDS-risk subgroup patients have developed AIDS with a 14% (two of 14) mortality. Herpes zoster ophthalmicus in AIDS-risk group members appeared to be an early clinical marker for the immune deficiency induced by AIDS retroviral infection.
- Published
- 1986
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