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The HPLC retention of indometacin lyophilisates in presence of different cationic and anionic ion-interaction-reagents (IIR) will be investigated. The effect of various factors of influence (pH, organic modifier, buffer concentration) on the capacity factor will be described and discussed.

Jockeys based on racing stables in the Newmarket and Epsom areas of England were screened using the 26-item Eating Attitudes Test. The mean score of the EAT was 14.9, significantly above that reported for males in other studies. The response rate was poor, but 10 jockeys agreed to a full psychiatric and eating interview. The majority of jockeys interviewed reported food avoidance, the use of saunas, and the abuse of laxatives. Diuretics and appetite suppressants were also used. Bingeing was common, but self-induced vomiting was unusual. Current weights were 13% below, and the lowest reported weights 21% below, matched population mean weights. The relationship between these forms of eating behaviour and clinical eating disorders is discussed.

Twenty-two men, who had been forcibly sexually assaulted, participated in a study to determine the circumstances of the attacks and the effects on the victims. The immediate and long-term responses were very similar to those described in female victims of rape.

Cavities in the septum pellucidum are widely regarded as incidental findings of little clinical importance. The prevalence of such cava on computerized tomography in a mixed sample of 22000 neurological and psychiatric patients is found to be 0.15%. A statistical association between this anomaly and a referral diagnosis of functional psychosis is reported, and 6 cases are described. These cases were male and characterized by an early history of developmental delay, with lifelong disturbances of emotion and behaviour prior to the onset in early adulthood of an atypical schizophrenia-like psychosis with disorders of speech and movement. It is suggested that septal cavities may signal an underlying abnormality of function relevant to the pathogenesis of these illnesses.