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152. Estimativa multivariada de padrões alimentares: o todo é diferente da reunião das partes?

Author

Iolanda Karla Santana dos Santos, Wolney Lisbôa Conde, and Alicia Matijasevich Manitto

Subjects
Epidemiologia, Vigilância, Comportamento alimentar, Public aspects of medicine, RA1-1270
Abstract

RESUMO: Objetivo: Descrever as correlações entre padrões alimentares para o conjunto de anos de 2007 a 2012 e para cada ano do mesmo período. Método: Estudo transversal com dados do Sistema de Vigilância de Fatores de Risco e Proteção para Doenças Crônicas por Inquérito Telefônico, com seleção de 167.761 indivíduos de 18 a 44 anos. Os padrões alimentares foram identificados com Análise de Componentes Principais. Para comparar os efeitos da extração e a estimativa de padrões alimentares entre diferentes inquéritos, conduzimos as seguintes análises: na primeira usamos o conjunto total de dados para os anos de 2007 a 2012; na segunda, os padrões foram estimados em cada conjunto anual de dados para o período de 2007 a 2012. As etapas 1 e 2 foram realizadas sem rotação, com rotação Varimax e rotação Promax. Após a extração dos padrões, foram calculados escores padronizados com média zero. A associação entre os padrões gerados nas análises foi estimada pelo coeficiente de correlação de Pearson (r). Resultados: Nas análises sem rotação, os componentes retidos no conjunto apresentaram correlações superiores a 0,90 com os padrões retidos em cada ano. Nas análises com rotação, apenas o primeiro componente apresentou correlações superiores a 0,90. Conclusão: As estimativas de padrões alimentares de forma segmentada - ano a ano - ou de forma geral - todos os anos - apresentam altas correlação e consistência entre os padrões identificados quando no mesmo pool de dados.

Published
2020
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153. Maternal Parenting Electronic Diary in the Context of a Home Visit Intervention for Adolescent Mothers in an Urban Deprived Area of São Paulo, Brazil: Randomized Controlled Trial

Author

Fatori, Daniel, Argeu, Adriana, Brentani, Helena, Chiesa, Anna, Fracolli, Lislaine, Matijasevich, Alicia, Miguel, Euripedes C, and Polanczyk, Guilherme

Subjects
Information technology, T58.5-58.64, Public aspects of medicine, RA1-1270
Abstract

BackgroundPregnancy during adolescence is prevalent in low- and middle-income countries (LMICs), which is associated with various adverse outcomes that can be prevented with home visiting programs. However, testing these interventions in LMICs can be challenging due to limited resources. The use of electronic data collection via smartphones can be an alternative and ideal low-cost method to measure outcomes in an environment with adverse conditions. ObjectiveOur study had two objectives: to test the efficacy of a nurse home visiting intervention on maternal parenting and well-being measured by an electronic daily diary (eDiary), and to investigate the compliance rate of the eDiary measurement method. MethodsWe conducted a randomized controlled trial to test the efficacy of Primeiros Laços, a nurse home visiting program, for adolescent mothers living in an urban deprived area of São Paulo, Brazil. A total of 169 pregnant adolescents were assessed for eligibility criteria, 80 of whom were included and randomized to the intervention (n=40) and control group (care as usual, n=40). Primeiros Laços is a home visiting intervention delivered by trained nurses tailored to first-time pregnant adolescents and their children, starting during the first 16 weeks of pregnancy until the child reaches 24 months of age. Participants were assessed by blind interviewers at 8-16 weeks of pregnancy (baseline), 30 weeks of pregnancy, and when the child was 3, 6, and 12 months of age. At 18 months, participants were assessed regarding maternal parenting and parental well-being using a 7-consecutive-day eDiary. The smartphone app was programmed to notify participants every day at 9:00 PM over a period of seven days. ResultsWe were able to contact 57/80 (71%) participants (29 from the intervention group and 28 from the control group) when the child was 18 months of age. Forty-eight of the 57 participants (84%) completed at least one day of the eDiary protocol. The daily compliance rate ranged from 49% to 70%. Our analyses showed a significant effect of the intervention on parental well-being (B=0.32, 95% CI [0.06, 0.58], P=.02) and the maternal parenting behavior of the mother telling a story or singing to the child (odds ratio=2.33, 95% CI [1.20, 4.50], P=.01).Our analyses showed a significant effect of the intervention on parental well-being (B=0.32, P=.02) and the maternal parenting behavior of the mother telling a story or singing to the child (odds ratio=2.33, P=.01). ConclusionsThe Primeiros Laços intervention improved maternal parenting and parental well-being, demonstrating its promise for low-income adolescent mothers. The compliance rate of the eDiary assessment showed that it was generally accepted by adolescent mothers with limited resources. Future studies can implement ambulatory assessment in LMICs via smartphones to measure mother and child behaviors. Trial RegistrationClinicalTrials.gov NCT02807818; https://clinicaltrials.gov/ct2/show/NCT02807818

Published
2020
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154. Is intrauterine exposure to acetaminophen associated with emotional and hyperactivity problems during childhood? Findings from the 2004 Pelotas birth cohort

Author

Luciana Tovo-Rodrigues, Bruna Celestino Schneider, Thais Martins-Silva, Bianca Del-Ponte, Christian Loret de Mola, Lavinia Schuler-Faccini, Fernanda Sales Luiz Vianna, Tiago N. Munhoz, Ludmila Entiauspe, Mariângela Freitas Silveira, Iná S. Santos, Alicia Matijasevich, Aluísio J. D. Barros, Luis Augusto Rohde, and Andréa Dâmaso Bertoldi

Subjects
Acetaminophen (paracetamol), Prenatal exposure, Birth cohort, Behavioral symptoms, Psychiatry, RC435-571
Abstract

Abstract Background Longitudinal studies have consistently reported that prenatal exposure to acetaminophen can to lead to an increased risk of attention deficit-hyperactivity disorder during childhood. This study aimed to investigate the association between intrauterine exposure to acetaminophen and the presence of emotional and behavioral problems at the ages of 6 and 11 years in a low-middle income country. Methods We performed a prospective longitudinal population-based study using data from the 2004 Pelotas birth cohort. From the 4231 initial cohort participants, 3722 and 3566 children were assessed at 6 and 11 years of age, respectively. The outcomes were assessed using the parent version of Strengths and Difficulties Questionnaire (SDQ). The cut-off points established for the Brazilian population were used to categorize the outcomes. Crude and adjusted odds ratio were obtained through logistic regression. Results Acetaminophen was used by 27.5% (95% confidence interval [CI]: 26.1–28.9) of the mothers at least once during pregnancy. The prevalence of emotional problems at 6 and 11 years was 13.6 and 19.9%, respectively. For hyperactivity problems, prevalence was 13.9 and 16.1%, respectively. Intrauterine exposure to acetaminophen increased the odds of having emotional (odds ratio [OR] = 1.47; 95% CI: 1.07–2.02) and hyperactivity/inattention (OR = 1.42; 95% CI: 1.06–1.92) problems in 6-year-old boys. At the age of 11, a small decrease in the effect was observed for both outcomes after adjustment: OR = 1.31 (95% CI: 0.99–1.73) for emotional problems and OR = 1.25 (95% CI: 0.95–1.65) for hyperactivity/inattention in boys. No association for any phenotypes at both ages was observed for girls. Conclusion The effect of intrauterine exposure to acetaminophen in emotional and hyperactivity symptoms was dependent on sex in a Brazilian cohort. While it seemed to be important for boys, mainly at 6 years of age, for girls, no association was observed.

Published
2018
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155. Effect of correcting for gestational age at birth on population prevalence of early childhood undernutrition

Author

Nandita Perumal, Daniel E. Roth, Johnna Perdrizet, Aluísio J. D. Barros, Iná S. Santos, Alicia Matijasevich, and Diego G. Bassani

Subjects
World Health Organization Growth Standards (WHO-GS), Gestational age, Growth, Preterm birth, Pediatrics, INTERGROWTH newborn size standard, Infectious and parasitic diseases, RC109-216
Abstract

Abstract Background Postmenstrual and/or gestational age-corrected age (CA) is required to apply child growth standards to children born preterm (

Published
2018
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156. Perception of parents and caregivers about the need for dental appointments for adolescents from a Brazilian birth cohort

Author

Tillmann, Thais Freitas Formozo, primary, de Camargo, Maria Beatriz Junqueira, additional, Cascaes, Andréia Morales, additional, Barros, Aluísio J. D., additional, Santos, Iná S., additional, Corrêa, Marcos Britto, additional, Matijasevich, Alicia, additional, D'Ávila, Otávio Pereira, additional, and Silva, Alexandre Emidio Ribeiro, additional

Published
2023
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158. Pathways from maternal depression to child resilience: Socioeconomic, family, and individual factors in the 2004 Pelotas (Brazil) birth cohort

Author

Maruyama, Jessica Mayumi, primary, Bauer, Andreas, additional, Hammerton, Gemma, additional, Halligan, Sarah L., additional, Santos, Ina S., additional, Munhoz, Tiago N., additional, Barros, Aluísio J. D., additional, Barros, Fernando C., additional, Fairchild, Graeme, additional, and Matijasevich, Alicia, additional

Published
2023
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159. T52. GENETICS – CHILDHOOD MALTREATMENT CORRELATION EFFECT IN ATTENTION DEFICIT HYPERACTIVITY DISORDER SYMPTOMS IN EARLY ADULTHOOD: EVIDENCE FROM THE 2004 PELOTAS (BRAZIL) BIRTH COHORT

Author

Tovo-Rodrigues, Luciana, primary, Hutz, Mara, additional, Camerini, Laísa, additional, Martins-Silva, Thais, additional, Carpena, Marina X, additional, Bonilla, Carolina, additional, Oliveira, Isabel O, additional, de Paula, Cristiane Silvestre, additional, Murray, Joseph, additional, Barros, Aluísio JD, additional, Santos, Iná S., additional, Rohde, Luis A, additional, Genro, Julia P, additional, and Matijasevich, Alicia, additional

Published
2023
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163. Gender gap for accelerometry-based physical activity across different age groups in five Brazilian cohort studies

Author

Ricardo, Luiza IC, primary, Wendt, Andrea, additional, Tornquist, Debora, additional, Goncalves, Helen, additional, Wehrmeister, Fernando, additional, da Silva, Bruna Goncalves C., additional, Rodrigues, Luciana Tovo, additional, dos Santos, Ina da Silva, additional, Barros, Aluisio, additional, Matijasevich, Alicia, additional, Hallal, Pedro, additional, Domingues, Marlos Rodrigues, additional, Ekelund, Ulf, additional, Bieleman, Renata, additional, and Crochemore-Silva, Inacio, additional

Published
2023
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164. Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults

Author

Abarca-Gómez, Leandra, Abdeen, Ziad A, Hamid, Zargar Abdul, Abu-Rmeileh, Niveen M, Acosta-Cazares, Benjamin, Acuin, Cecilia, Adams, Robert J, Aekplakorn, Wichai, Afsana, Kaosar, Aguilar-Salinas, Carlos A, Agyemang, Charles, Ahmadvand, Alireza, Ahrens, Wolfgang, Ajlouni, Kamel, Akhtaeva, Nazgul, Al-Hazzaa, Hazzaa M, Al-Othman, Amani Rashed, Al-Raddadi, Rajaa, Al Buhairan, Fadia, Al Dhukair, Shahla, Ali, Mohamed M, Ali, Osman, Alkerwi, Ala'a, Alvarez-Pedrerol, Mar, Aly, Eman, Amarapurkar, Deepak N, Amouyel, Philippe, Amuzu, Antoinette, Andersen, Lars Bo, Anderssen, Sigmund A, Andrade, Dolores S, Ängquist, Lars H, Anjana, Ranjit Mohan, Aounallah-Skhiri, Hajer, Araújo, Joana, Ariansen, Inger, Aris, Tahir, Arlappa, Nimmathota, Arveiler, Dominique, Aryal, Krishna K, Aspelund, Thor, Assah, Felix K, Assunção, Maria Cecília F, Aung, May Soe, Avdicová, Mária, Azevedo, Ana, Azizi, Fereidoun, Babu, Bontha V, Bahijri, Suhad, Baker, Jennifer L, Balakrishna, Nagalla, Bamoshmoosh, Mohamed, Banach, Maciej, Bandosz, Piotr, Banegas, José R, Barbagallo, Carlo M, Barceló, Alberto, Barkat, Amina, Barros, Aluisio JD, Barros, Mauro VG, Bata, Iqbal, Batieha, Anwar M, Batista, Rosangela L, Batyrbek, Assembekov, Baur, Louise A, Beaglehole, Robert, Romdhane, Habiba Ben, Benedics, Judith, Benet, Mikhail, Bennett, James E, Bernabe-Ortiz, Antonio, Bernotiene, Gailute, Bettiol, Heloisa, Bhagyalaxmi, Aroor, Bharadwaj, Sumit, Bhargava, Santosh K, Bhatti, Zaid, Bhutta, Zulfiqar A, Bi, Hongsheng, Bi, Yufang, Biehl, Anna, Bikbov, Mukharram, Bista, Bihungum, Bjelica, Dusko J, Bjerregaard, Peter, Bjertness, Espen, Bjertness, Marius B, Björkelund, Cecilia, Blokstra, Anneke, Bo, Simona, Bobak, Martin, Boddy, Lynne M, Boehm, Bernhard O, Boeing, Heiner, Boggia, Jose G, Boissonnet, Carlos P, Bonaccio, Marialaura, Bongard, Vanina, Bovet, Pascal, Braeckevelt, Lien, Braeckman, Lutgart, Bragt, Marjolijn CE, Brajkovich, Imperia, Branca, Francesco, Breckenkamp, Juergen, Breda, João, Brenner, Hermann, Brewster, Lizzy M, Brian, Garry R, Brinduse, Lacramioara, Bruno, Graziella, Bueno-de-Mesquita, H B(as), Bugge, Anna, Buoncristiano, Marta, Burazeri, Genc, Burns, Con, de León, Antonio Cabrera, Cacciottolo, Joseph, Cai, Hui, Cama, Tilema, Cameron, Christine, Camolas, José, Can, Günay, Cândido, Ana Paula C, Capanzana, Mario, Capuano, Vincenzo, Cardoso, Viviane C, Carlsson, Axel C, Carvalho, Maria J, Casanueva, Felipe F, Casas, Juan-Pablo, Caserta, Carmelo A, Chamukuttan, Snehalatha, Chan, Angelique W, Chan, Queenie, Chaturvedi, Himanshu K, Chaturvedi, Nishi, Chen, Chien-Jen, Chen, Fangfang, Chen, Huashuai, Chen, Shuohua, Chen, Zhengming, Cheng, Ching-Yu, Chetrit, Angela, Chikova-Iscener, Ekaterina, Chiolero, Arnaud, Chiou, Shu-Ti, Chirita-Emandi, Adela, Chirlaque, María-Dolores, Cho, Belong, Cho, Yumi, Christensen, Kaare, Christofaro, Diego G, Chudek, Jerzy, Cifkova, Renata, Cinteza, Eliza, Claessens, Frank, Clays, Els, Concin, Hans, Confortin, Susana C, Cooper, Cyrus, Cooper, Rachel, Coppinger, Tara C, Costanzo, Simona, Cottel, Dominique, Cowell, Chris, Craig, Cora L, Crujeiras, Ana B, Cucu, Alexandra, D'Arrigo, Graziella, d'Orsi, Eleonora, Dallongeville, Jean, Damasceno, Albertino, Damsgaard, Camilla T, Danaei, Goodarz, Dankner, Rachel, Dantoft, Thomas M, Dastgiri, Saeed, Dauchet, Luc, Davletov, Kairat, De Backer, Guy, De Bacquer, Dirk, De Curtis, Amalia, de Gaetano, Giovanni, De Henauw, Stefaan, de Oliveira, Paula Duarte, De Ridder, Karin, De Smedt, Delphine, Deepa, Mohan, Deev, Alexander D, Dehghan, Abbas, Delisle, Hélène, Delpeuch, Francis, Deschamps, Valérie, Dhana, Klodian, Di Castelnuovo, Augusto F, Dias-da-Costa, Juvenal Soares, Diaz, Alejandro, Dika, Zivka, Djalalinia, Shirin, Do, Ha TP, Dobson, Annette J, Donati, Maria Benedetta, Donfrancesco, Chiara, Donoso, Silvana P, Döring, Angela, Dorobantu, Maria, Dorosty, Ahmad Reza, Doua, Kouamelan, Drygas, Wojciech, Duan, Jia Li, Duante, Charmaine, Duleva, Vesselka, Dulskiene, Virginija, Dzerve, Vilnis, Dziankowska-Zaborszczyk, Elzbieta, Egbagbe, Eruke E, Eggertsen, Robert, Eiben, Gabriele, Ekelund, Ulf, El Ati, Jalila, Elliott, Paul, Engle-Stone, Reina, Erasmus, Rajiv T, Erem, Cihangir, Eriksen, Louise, Eriksson, Johan G, la Peña, Jorge Escobedo-de, Evans, Alun, Faeh, David, Fall, Caroline H, Sant'Angelo, Victoria Farrugia, Farzadfar, Farshad, Felix-Redondo, Francisco J, Ferguson, Trevor S, Fernandes, Romulo A, Fernández-Bergés, Daniel, Ferrante, Daniel, Ferrari, Marika, Ferreccio, Catterina, Ferrieres, Jean, Finn, Joseph D, Fischer, Krista, Flores, Eric Monterubio, Föger, Bernhard, Foo, Leng Huat, Forslund, Ann-Sofie, Forsner, Maria, Fouad, Heba M, Francis, Damian K, Franco, Maria do Carmo, Franco, Oscar H, Frontera, Guillermo, Fuchs, Flavio D, Fuchs, Sandra C, Fujita, Yuki, Furusawa, Takuro, Gaciong, Zbigniew, Gafencu, Mihai, Galeone, Daniela, Galvano, Fabio, Garcia-de-la-Hera, Manoli, Gareta, Dickman, Garnett, Sarah P, Gaspoz, Jean-Michel, Gasull, Magda, Gates, Louise, Geiger, Harald, Geleijnse, Johanna M, Ghasemian, Anoosheh, Giampaoli, Simona, Gianfagna, Francesco, Gill, Tiffany K, Giovannelli, Jonathan, Giwercman, Aleksander, Godos, Justyna, Gogen, Sibel, Goldsmith, Rebecca A, Goltzman, David, Gonçalves, Helen, González-Leon, Margot, González-Rivas, Juan P, Gonzalez-Gross, Marcela, Gottrand, Frederic, Graça, Antonio Pedro, Graff-Iversen, Sidsel, Grafnetter, Dušan, Grajda, Aneta, Grammatikopoulou, Maria G, Gregor, Ronald D, Grodzicki, Tomasz, Grøntved, Anders, Grosso, Giuseppe, Gruden, Gabriella, Grujic, Vera, Gu, Dongfeng, Gualdi-Russo, Emanuela, Guallar-Castillón, Pilar, Guan, Ong Peng, Gudmundsson, Elias F, Gudnason, Vilmundur, Guerrero, Ramiro, Guessous, Idris, Guimaraes, Andre L, Gulliford, Martin C, Gunnlaugsdottir, Johanna, Gunter, Marc, Guo, Xiuhua, Guo, Yin, Gupta, Prakash C, Gupta, Rajeev, Gureje, Oye, Gurzkowska, Beata, Gutierrez, Laura, Gutzwiller, Felix, Hadaegh, Farzad, Hadjigeorgiou, Charalambos A, Si-Ramlee, Khairil, Halkjær, Jytte, Hambleton, Ian R, Hardy, Rebecca, Kumar, Rachakulla Hari, Hassapidou, Maria, Hata, Jun, Hayes, Alison J, He, Jiang, Heidinger-Felso, Regina, Heinen, Mirjam, Hendriks, Marleen Elisabeth, Henriques, Ana, Cadena, Leticia Hernandez, Herrala, Sauli, Herrera, Victor M, Herter-Aeberli, Isabelle, Heshmat, Ramin, Hihtaniemi, Ilpo Tapani, Ho, Sai Yin, Ho, Suzanne C, Hobbs, Michael, Hofman, Albert, Hopman, Wilma M, Horimoto, Andrea RVR, Hormiga, Claudia M, Horta, Bernardo L, Houti, Leila, Howitt, Christina, Htay, Thein Thein, Htet, Aung Soe, Htike, Maung Maung Than, Hu, Yonghua, Huerta, José María, Petrescu, Constanta Huidumac, Huisman, Martijn, Husseini, Abdullatif, Huu, Chinh Nguyen, Huybrechts, Inge, Hwalla, Nahla, Hyska, Jolanda, Iacoviello, Licia, Iannone, Anna G, Ibarluzea, Jesús M, Ibrahim, Mohsen M, Ikeda, Nayu, Ikram, M Arfan, Irazola, Vilma E, Islam, Muhammad, Ismail, Aziz al-Safi, Ivkovic, Vanja, Iwasaki, Masanori, Jackson, Rod T, Jacobs, Jeremy M, Jaddou, Hashem, Jafar, Tazeen, Jamil, Kazi M, Jamrozik, Konrad, Janszky, Imre, Jarani, Juel, Jasienska, Grazyna, Jelakovic, Ana, Jelakovic, Bojan, Jennings, Garry, Jeong, Seung-Lyeal, Jiang, Chao Qiang, Jiménez-Acosta, Santa Magaly, Joffres, Michel, Johansson, Mattias, Jonas, Jost B, Jørgensen, Torben, Joshi, Pradeep, Jovic, Dragana P, Józwiak, Jacek, Juolevi, Anne, Jurak, Gregor, Jureša, Vesna, Kaaks, Rudolf, Kafatos, Anthony, Kajantie, Eero O, Kalter-Leibovici, Ofra, Kamaruddin, Nor Azmi, Kapantais, Efthymios, Karki, Khem B, Kasaeian, Amir, Katz, Joanne, Kauhanen, Jussi, Kaur, Prabhdeep, Kavousi, Maryam, Kazakbaeva, Gyulli, Keil, Ulrich, Boker, Lital Keinan, Keinänen-Kiukaanniemi, Sirkka, Kelishadi, Roya, Kelleher, Cecily, Kemper, Han CG, Kengne, Andre P, Kerimkulova, Alina, Kersting, Mathilde, Key, Timothy, Khader, Yousef Saleh, Khalili, Davood, Khang, Young-Ho, Khateeb, Mohammad, Khaw, Kay-Tee, Khouw, Ilse MSL, Kiechl-Kohlendorfer, Ursula, Kiechl, Stefan, Killewo, Japhet, Kim, Jeongseon, Kim, Yeon-Yong, Klimont, Jeannette, Klumbiene, Jurate, Knoflach, Michael, Koirala, Bhawesh, Kolle, Elin, Kolsteren, Patrick, Korrovits, Paul, Kos, Jelena, Koskinen, Seppo, Kouda, Katsuyasu, Kovacs, Viktoria A, Kowlessur, Sudhir, Koziel, Slawomir, Kratzer, Wolfgang, Kriemler, Susi, Kristensen, Peter Lund, Krokstad, Steinar, Kromhout, Daan, Kruger, Herculina S, Kubinova, Ruzena, Kuciene, Renata, Kuh, Diana, Kujala, Urho M, Kulaga, Zbigniew, Kumar, R Krishna, Kunešová, Marie, Kurjata, Pawel, Kusuma, Yadlapalli S, Kuulasmaa, Kari, Kyobutungi, Catherine, La, Quang Ngoc, Laamiri, Fatima Zahra, Laatikainen, Tiina, Lachat, Carl, Laid, Youcef, Lam, Tai Hing, Landrove, Orlando, Lanska, Vera, Lappas, Georg, Larijani, Bagher, Laugsand, Lars E, Lauria, Laura, Laxmaiah, Avula, Bao, Khanh Le Nguyen, Le, Tuyen D, Lebanan, May Antonnette O, Leclercq, Catherine, Lee, Jeannette, Lee, Jeonghee, Lehtimäki, Terho, León-Muñoz, Luz M, Levitt, Naomi S, Li, Yanping, Lilly, Christa L, Lim, Wei-Yen, Lima-Costa, M Fernanda, Lin, Hsien-Ho, Lin, Xu, Lind, Lars, Linneberg, Allan, Lissner, Lauren, Litwin, Mieczyslaw, Liu, Jing, Loit, Helle-Mai, Lopes, Luis, Lorbeer, Roberto, Lotufo, Paulo A, Lozano, José Eugenio, Luksiene, Dalia, Lundqvist, Annamari, Lunet, Nuno, Lytsy, Per, Ma, Guansheng, Ma, Jun, Machado-Coelho, George LL, Machado-Rodrigues, Aristides M, Machi, Suka, Maggi, Stefania, Magliano, Dianna J, Magriplis, Emmanuella, Mahaletchumy, Alagappan, Maire, Bernard, Majer, Marjeta, Makdisse, Marcia, Malekzadeh, Reza, Malhotra, Rahul, Rao, Kodavanti Mallikharjuna, Malyutina, Sofia, Manios, Yannis, Mann, Jim I, Manzato, Enzo, Margozzini, Paula, Markaki, Anastasia, Markey, Oonagh, Marques, Larissa P, Marques-Vidal, Pedro, Marrugat, Jaume, Martin-Prevel, Yves, Martin, Rosemarie, Martorell, Reynaldo, Martos, Eva, Marventano, Stefano, Masoodi, Shariq R, Mathiesen, Ellisiv B, Matijasevich, Alicia, Matsha, Tandi E, Mazur, Artur, Mbanya, Jean Claude N, McFarlane, Shelly R, McGarvey, Stephen T, McKee, Martin, McLachlan, Stela, McLean, Rachael M, McLean, Scott B, McNulty, Breige A, Yusof, Safiah Md, Mediene-Benchekor, Sounnia, Medzioniene, Jurate, Meirhaeghe, Aline, Meisfjord, Jørgen, Meisinger, Christa, Menezes, Ana Maria B, Menon, Geetha R, Mensink, Gert BM, Meshram, Indrapal I, Metspalu, Andres, Meyer, Haakon E, Mi, Jie, Michaelsen, Kim F, Michels, Nathalie, Mikkel, Kairit, Miller, Jody C, Minderico, Cláudia S, Miquel, Juan Francisco, Miranda, J Jaime, Mirkopoulou, Daphne, Mirrakhimov, Erkin, Mišigoj-Durakovic, Marjeta, Mistretta, Antonio, Mocanu, Veronica, Modesti, Pietro A, Mohamed, Mostafa K, Mohammad, Kazem, Mohammadifard, Noushin, Mohan, Viswanathan, Mohanna, Salim, Yusoff, Muhammad Fadhli Mohd, Molbo, Drude, Møllehave, Line T, Møller, Niels C, Molnár, Dénes, Momenan, Amirabbas, Mondo, Charles K, Monterrubio, Eric A, Monyeki, Kotsedi Daniel K, Moon, Jin Soo, Moreira, Leila B, Morejon, Alain, Moreno, Luis A, Morgan, Karen, Mortensen, Erik Lykke, Moschonis, George, Mossakowska, Malgorzata, Mostafa, Aya, Mota, Jorge, Mota-Pinto, Anabela, Motlagh, Mohammad Esmaeel, Motta, Jorge, Mu, Thet Thet, Muc, Magdalena, Muiesan, Maria Lorenza, Müller-Nurasyid, Martina, Murphy, Neil, Mursu, Jaakko, Murtagh, Elaine M, Musil, Vera, Nabipour, Iraj, Nagel, Gabriele, Naidu, Balkish M, Nakamura, Harunobu, Námešná, Jana, Nang, Ei Ei K, Nangia, Vinay B, Nankap, Martin, Narake, Sameer, Nardone, Paola, Navarrete-Muñoz, Eva Maria, Neal, William A, Nenko, Ilona, Neovius, Martin, Nervi, Flavio, Nguyen, Chung T, Nguyen, Nguyen D, Nguyen, Quang Ngoc, Nieto-Martínez, Ramfis E, Ning, Guang, Ninomiya, Toshiharu, Nishtar, Sania, Noale, Marianna, Noboa, Oscar A, Norat, Teresa, Norie, Sawada, Noto, Davide, Nsour, Mohannad Al, O'Reilly, Dermot, Obreja, Galina, Oda, Eiji, Oehlers, Glenn, Oh, Kyungwon, Ohara, Kumiko, Olafsson, Örn, Olinto, Maria Teresa Anselmo, Oliveira, Isabel O, Oltarzewski, Maciej, Omar, Mohd Azahadi, Onat, Altan, Ong, Sok King, Ono, Lariane M, Ordunez, Pedro, Ornelas, Rui, Ortiz, Ana P, Osler, Merete, Osmond, Clive, Ostojic, Sergej M, Ostovar, Afshin, Otero, Johanna A, Overvad, Kim, Owusu-Dabo, Ellis, Paccaud, Fred Michel, Padez, Cristina, Pahomova, Elena, Pajak, Andrzej, Palli, Domenico, Palloni, Alberto, Palmieri, Luigi, Pan, Wen-Harn, Panda-Jonas, Songhomitra, Pandey, Arvind, Panza, Francesco, Papandreou, Dimitrios, Park, Soon-Woo, Parnell, Winsome R, Parsaeian, Mahboubeh, Pascanu, Ionela M, Patel, Nikhil D, Pecin, Ivan, Pednekar, Mangesh S, Peer, Nasheeta, Peeters, Petra H, Peixoto, Sergio Viana, Peltonen, Markku, Pereira, Alexandre C, Perez-Farinos, Napoleon, Pérez, Cynthia M, Peters, Annette, Petkeviciene, Janina, Petrauskiene, Ausra, Peykari, Niloofar, Pham, Son Thai, Pierannunzio, Daniela, Pigeot, Iris, Pikhart, Hynek, Pilav, Aida, Pilotto, Lorenza, Pistelli, Francesco, Pitakaka, Freda, Piwonska, Aleksandra, Plans-Rubió, Pedro, Poh, Bee Koon, Pohlabeln, Hermann, Pop, Raluca M, Popovic, Stevo R, Porta, Miquel, Portegies, Marileen LP, Posch, Georg, Poulimeneas, Dimitrios, Pouraram, Hamed, Pourshams, Akram, Poustchi, Hossein, Pradeepa, Rajendra, Prashant, Mathur, Price, Jacqueline F, Puder, Jardena J, Pudule, Iveta, Puiu, Maria, Punab, Margus, Qasrawi, Radwan F, Qorbani, Mostafa, Bao, Tran Quoc, Radic, Ivana, Radisauskas, Ricardas, Rahman, Mahfuzar, Rahman, Mahmudur, Raitakari, Olli, Raj, Manu, Rao, Sudha Ramachandra, Ramachandran, Ambady, Ramke, Jacqueline, Ramos, Elisabete, Ramos, Rafel, Rampal, Lekhraj, Rampal, Sanjay, Rascon-Pacheco, Ramon A, Redon, Josep, Reganit, Paul Ferdinand M, Ribas-Barba, Lourdes, Ribeiro, Robespierre, Riboli, Elio, Rigo, Fernando, de Wit, Tobias F Rinke, Rito, Ana, Ritti-Dias, Raphael M, Rivera, Juan A, Robinson, Sian M, Robitaille, Cynthia, Rodrigues, Daniela, Rodríguez-Artalejo, Fernando, del Cristo Rodriguez-Perez, María, Rodríguez-Villamizar, Laura A, Rojas-Martinez, Rosalba, Rojroongwasinkul, Nipa, Romaguera, Dora, Ronkainen, Kimmo, Rosengren, Annika, Rouse, Ian, Roy, Joel GR, Rubinstein, Adolfo, Rühli, Frank J, Ruiz-Betancourt, Blanca Sandra, Russo, Paola, Rutkowski, Marcin, Sabanayagam, Charumathi, Sachdev, Harshpal S, Saidi, Olfa, Salanave, Benoit, Martinez, Eduardo Salazar, Salmerón, Diego, Salomaa, Veikko, Salonen, Jukka T, Salvetti, Massimo, Sánchez-Abanto, Jose, Sandjaja, Sans, Susana, Marina, Loreto Santa, Santos, Diana A, Santos, Ina S, Santos, Osvaldo, dos Santos, Renata Nunes, Santos, Rute, Saramies, Jouko L, Sardinha, Luis B, Sarrafzadegan, Nizal, Saum, Kai-Uwe, Savva, Savvas, Savy, Mathilde, Scazufca, Marcia, Rosario, Angelika Schaffrath, Schargrodsky, Herman, Schienkiewitz, Anja, Schipf, Sabine, Schmidt, Carsten O, Schmidt, Ida Maria, Schultsz, Constance, Schutte, Aletta E, Sein, Aye Aye, Sen, Abhijit, Senbanjo, Idowu O, Sepanlou, Sadaf G, Serra-Majem, Luis, Shalnova, Svetlana A, Sharma, Sanjib K, Shaw, Jonathan E, Shibuya, Kenji, Shin, Dong Wook, Shin, Youchan, Shiri, Rahman, Siani, Alfonso, Siantar, Rosalynn, Sibai, Abla M, Silva, Antonio M, Silva, Diego Augusto Santos, Simon, Mary, Simons, Judith, Simons, Leon A, Sjöberg, Agneta, Sjöström, Michael, Skovbjerg, Sine, Slowikowska-Hilczer, Jolanta, Slusarczyk, Przemyslaw, Smeeth, Liam, Smith, Margaret C, Snijder, Marieke B, So, Hung-Kwan, Sobngwi, Eugène, Söderberg, Stefan, Soekatri, Moesijanti YE, Solfrizzi, Vincenzo, Sonestedt, Emily, Song, Yi, Sørensen, Thorkild IA, Soric, Maroje, Jérome, Charles Sossa, Soumare, Aicha, Spinelli, Angela, Spiroski, Igor, Staessen, Jan A, Stamm, Hanspeter, Starc, Gregor, Stathopoulou, Maria G, Staub, Kaspar, Stavreski, Bill, Steene-Johannessen, Jostein, Stehle, Peter, Stein, Aryeh D, Stergiou, George S, Stessman, Jochanan, Stieber, Jutta, Stöckl, Doris, Stocks, Tanja, Stokwiszewski, Jakub, Stratton, Gareth, Stronks, Karien, Strufaldi, Maria Wany, Suárez-Medina, Ramón, Sun, Chien-An, Sundström, Johan, Sung, Yn-Tz, Sunyer, Jordi, Suriyawongpaisal, Paibul, Swinburn, Boyd A, Sy, Rody G, Szponar, Lucjan, Tai, E Shyong, Tammesoo, Mari-Liis, Tamosiunas, Abdonas, Tan, Eng Joo, Tang, Xun, Tanser, Frank, Tao, Yong, Tarawneh, Mohammed Rasoul, Tarp, Jakob, Tarqui-Mamani, Carolina B, Tautu, Oana-Florentina, Braunerová, Radka Taxová, Taylor, Anne, Tchibindat, Félicité, Theobald, Holger, Theodoridis, Xenophon, Thijs, Lutgarde, Thuesen, Betina H, Tjonneland, Anne, Tolonen, Hanna K, Tolstrup, Janne S, Topbas, Murat, Topór-Madry, Roman, Tormo, María José, Tornaritis, Michael J, Torrent, Maties, Toselli, Stefania, Traissac, Pierre, Trichopoulos, Dimitrios, Trichopoulou, Antonia, Trinh, Oanh TH, Trivedi, Atul, Tshepo, Lechaba, Tsigga, Maria, Tsugane, Shoichiro, Tulloch-Reid, Marshall K, Tullu, Fikru, Tuomainen, Tomi-Pekka, Tuomilehto, Jaakko, Turley, Maria L, Tynelius, Per, Tzotzas, Themistoklis, Tzourio, Christophe, Ueda, Peter, Ugel, Eunice E, Ukoli, Flora AM, Ulmer, Hanno, Unal, Belgin, Uusitalo, Hannu MT, Valdivia, Gonzalo, Vale, Susana, Valvi, Damaskini, van der Schouw, Yvonne T, Van Herck, Koen, Van Minh, Hoang, van Rossem, Lenie, Van Schoor, Natasja M, van Valkengoed, Irene GM, Vanderschueren, Dirk, Vanuzzo, Diego, Vatten, Lars, Vega, Tomas, Veidebaum, Toomas, Velasquez-Melendez, Gustavo, Velika, Biruta, Veronesi, Giovanni, Verschuren, WM Monique, Victora, Cesar G, Viegi, Giovanni, Viet, Lucie, Viikari-Juntura, Eira, Vineis, Paolo, Vioque, Jesus, Virtanen, Jyrki K, Visvikis-Siest, Sophie, Viswanathan, Bharathi, Vlasoff, Tiina, Vollenweider, Peter, Völzke, Henry, Voutilainen, Sari, Vrijheid, Martine, Wade, Alisha N, Wagner, Aline, Waldhör, Thomas, Walton, Janette, Bebakar, Wan Mohamad Wan, Mohamud, Wan Nazaimoon Wan, Wanderley, Rildo S, Jr., Wang, Ming-Dong, Wang, Qian, Wang, Ya Xing, Wang, Ying-Wei, Wannamethee, S Goya, Wareham, Nicholas, Weber, Adelheid, Wedderkopp, Niels, Weerasekera, Deepa, Whincup, Peter H, Widhalm, Kurt, Widyahening, Indah S, Wiecek, Andrzej, Wijga, Alet H, Wilks, Rainford J, Willeit, Johann, Willeit, Peter, Wilsgaard, Tom, Wojtyniak, Bogdan, Wong-McClure, Roy A, Wong, Justin YY, Wong, Jyh Eiin, Wong, Tien Yin, Woo, Jean, Woodward, Mark, Wu, Frederick C, Wu, Jianfeng, Wu, Shouling, Xu, Haiquan, Xu, Liang, Yamborisut, Uruwan, Yan, Weili, Yang, Xiaoguang, Yardim, Nazan, Ye, Xingwang, Yiallouros, Panayiotis K, Yngve, Agneta, Yoshihara, Akihiro, You, Qi Sheng, Younger-Coleman, Novie O, Yusoff, Faudzi, Yusoff, Muhammad Fadhli M, Zaccagni, Luciana, Zafiropulos, Vassilis, Zainuddin, Ahmad A, Zambon, Sabina, Zampelas, Antonis, Zamrazilová, Hana, Zdrojewski, Tomasz, Zeng, Yi, Zhao, Dong, Zhao, Wenhua, Zheng, Wei, Zheng, Yingfeng, Zholdin, Bekbolat, Zhou, Maigeng, Zhu, Dan, Zhussupov, Baurzhan, Zimmermann, Esther, Cisneros, Julio Zuñiga, Bentham, James, Di Cesare, Mariachiara, Bilano, Ver, Bixby, Honor, Zhou, Bin, Stevens, Gretchen A, Riley, Leanne M, Taddei, Cristina, Hajifathalian, Kaveh, Lu, Yuan, Savin, Stefan, Cowan, Melanie J, Paciorek, Christopher J, Kengne, Andre Pascal, Zhu, Aubrianna, and Ezzati, Majid

Published
2017
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170. Medical geneticists, genetic diseases and services in Brazil in the age of personalized medicine

Author

Carolina Bonilla, Vinicius Albuquerque Sortica, Lavinia Schuler-Faccini, Alicia Matijasevich, and Mário C Scheffer

Subjects
Pharmacology, Physicians, Humans, Molecular Medicine, General Medicine, Precision Medicine, Delivery of Health Care, Brazil
Abstract

Aim: In anticipation of the implementation of personalized medicine in Brazil the authors assessed the characteristics of its medical genetics workforce together with the distribution of genetic diseases and services across the country. Materials & methods: The authors used demographic data on medical specialties, and summarized data from the public and private healthcare systems on live births, hospitalization and mortality, for the years 2019 and 2020. Results: The distribution of medical geneticists (MGs) overlapped the country-wide distribution of genetic diseases and services examined, indicating that ∼30% of the patient population has access to a MG specialist. Graduate specialism in medical genetics, registered MGs and suitable workplaces were concentrated in the south and southeast regions, leaving the north and northeast deeply underserved. Conclusion: MGs are concentrated in the wealthiest and most populated areas, while other regions have very limited services. These inequalities should be addressed for a successful transition to personalized medicine.

Published
2022
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171. Perception of parents and caregivers about the need for dental appointments for adolescents from a Brazilian birth cohort.

Author

Tillmann, Thais Freitas Formozo, de Camargo, Maria Beatriz Junqueira, Cascaes, Andréia Morales, Barros, Aluísio J. D., Santos, Iná S., Corrêa, Marcos Britto, Matijasevich, Alicia, D'Ávila, Otávio Pereira, and Silva, Alexandre Emidio Ribeiro

Subjects
DENTAL care, SELF-evaluation, POISSON distribution, MALOCCLUSION, RESEARCH funding, PARENT-child relationships, PARENT attitudes, MULTIVARIATE analysis, DESCRIPTIVE statistics, LONGITUDINAL method, MEDICAL needs assessment, NEEDS assessment, CONFIDENCE intervals, SOCIODEMOGRAPHIC factors, DENTAL caries, CAREGIVER attitudes, MEDICAL referrals, ORAL health, TOOTHACHE
Abstract

Objective: To investigate the perception of parents or caregivers regarding the need for dental appointments for adolescents aged 12–13 years and associated factors. Methods: Data from the Pelotas 2004 Birth Cohort were used. The outcome variable was the need for dental appointments for young adolescents perceived by parents or caregivers. Demographic and economic exposure variables were obtained from the first (2004) and sixth general follow‐up (2015), respectively. The exposure variables 'previous history of dental pain', 'self‐rated oral health', clinical variables and the outcome variable were obtained from the second oral health follow‐up (2017). Unadjusted and adjusted multivariate Poisson regression analyses provided prevalence ratios (PR) and respective 95% confidence intervals (CI). Results: At the first oral health follow‐up (2009), 1303 five‐year‐old children were recruited, 996 of whom were reassessed and underwent oral health examinations at 12 and 13 years of age (response rate: 76.4%). The findings showed that 72.4% of parents/caregivers perceived that the adolescents needed dental appointments. No associations were found between the outcome and sociodemographic or economic variables. After adjustments, the outcome remained positively associated with previous history of toothache (PR 1.22; 95% CI 1.14–1.32), self‐rated oral health as fair or poor (PR 1.26; 95% CI 1.15–1.39), the presence of dental caries (PR 1.27; 95% CI 1.20–1.38) and severe or disabling malocclusion (PR 1.14; 95% CI 1.05–1.25). Conclusions: The perception of parents/caregivers regarding the need for dental appointments on the part of their adolescent sons and daughters was associated with oral health problems, and these findings can serve as the basis for creating and improving oral health programmes that seek a better understanding on the part of parents and caregivers regarding the importance of integral care for their adolescent children. [ABSTRACT FROM AUTHOR]

Published
2024
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172. Variation in ultra‐processed food consumption from 6 to 15 years, body weight and body composition at 15 years of age at The Pelotas 2004 Birth Cohort.

Author

Santos, Iná S., Bierhals, Isabel O., Costa, Caroline S., Matijasevich, Alicia, and Tovo‐Rodrigues, Luciana

Subjects
PACKAGED foods, FOOD consumption, BODY mass index, RESEARCH funding, CONVENIENCE foods, BODY weight, BODY composition, QUESTIONNAIRES, LOGISTIC regression analysis, DESCRIPTIVE statistics, ODDS ratio, REGRESSION analysis, OBESITY
Abstract

Summary: Background: The association of ultra‐processed food (UPF) consumption with obesity and adipose tissue in children/adolescents remains poorly understood. Objective: To assess the association of UPF consumption with excessive weight (EW—defined as BMI‐for‐age ≥+1 z‐score) and body composition at 15 years. Methods: In a birth cohort, daily UPF consumption was estimated by Food Frequency Questionnaires at 6 and 15 years. Those in the higher tercile of UPF consumption at both follow‐ups were the 'always‐high consumers'. Air‐displacement plethysmography provided fat mass (FM‐kg), fat‐free mass (FFM‐kg), %FM, %FFM, FM index (FMI‐kg/m2) and FFM index (FFMI‐kg/m2). Logistic regression and linear regression were used to estimate, respectively, odds ratios and beta coefficients. Results: Amongst 1584 participants, almost one in every seven were always‐high consumers. In crude analyses, there was no association between variation in UPF consumption and EW, and body fat parameters were lower in the always‐high consumer group than amongst the always‐low consumers, in both sexes. With adjustment for confounders, the odds ratio for EW was higher in the always‐high consumer than amongst the always‐low consumer group, and the direction of the associations with FM parameters was reversed: males from the always‐high consumer group presented almost twice as high FM (10.5 vs. 18.6 kg; p < 0.001) and twice as high FMI (3.4 vs. 6.3 kg/m2; p < 0.001) than the always‐low consumer group, and females from the always‐high consumer group presented on average 32% more FM and FMI than the always‐low consumer group. Conclusions: In crude and adjusted analyses there was a strong association between high UPF consumption from childhood to adolescence, EW and higher body fat parameters at 15 years, but its deleterious association with body adiposity was only uncovered after adjusting for confounders. [ABSTRACT FROM AUTHOR]

Published
2024
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173. Maternal depression and child development at 3 years of age: a longitudinal study in a Brazilian child development promotion program.

Author

Santos, Iná S., Blumenberg, Cauane, Munhoz, Tiago N., Matijasevich, Alicia, Salum, Cristiane, Santos Júnior, Hernane G., dos Santos, Letícia Marques, Correia, Luciano L., de Souza, Marta Rovery, Lira, Pedro I. C., Bortolotto, Caroline C., Barcelos, Raquel, Altafim, Elisa, Chicaro, Marina Fragata, Macana, Esmeralda Correa, and da Silva, Ronaldo Souza

Published
2024
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174. Structural Relationships between Asthma and Dental Caries in Children: A Birth Cohort Study in Southern Brazil.

Author

Agostini, Bernardo A., Sarkis-Onofre, Rafael, Ortiz, Fernanda R., Correa, Marcos B., Peres, Marco A., Peres, Karen G., Santos, Iná S., Matijasevich, Alícia, Barros, Fernando C.L.F., and Demarco, Flávio F.

Subjects
DENTAL caries, CHILDBIRTH, COHORT analysis, ASTHMA in children, STRUCTURAL equation modeling
Abstract

Introduction: There is an inconclusive causal association between asthma symptoms and dental caries in the primary dentition. This study aimed to investigate, using SEM (structural equation modeling), a possible causal relation between asthma and dental caries in the primary dentition. Methods: Using data from the 2004 Pelotas Birth Cohort Study, a sub-sample of 1,303 individuals was selected. Dental caries was clinically evaluated at 5 years old based on decayed, missing, and filled tooth (dmft) index criteria. Asthma-related symptoms (wheezing and shortness of breath) at 1- and 4-year-olds composed a latent variable and were the main exposures to caries occurrence. SEM was used to identify possible direct, indirect, and mediated effects of asthma in primary dentition dental caries. Results: The general prevalence of caries at age 5 was 1.95 (SD: 3.56). When comparing the dmft values for children with asthma symptoms and those without, they presented similar values in both periods where asthma symptoms were evaluated (1- and 4-year-old). SEM analysis showed that asthma was neither directly nor indirectly related to dental caries. Conclusion: Asthma, using a latent variable constructed based on asthma symptoms, showed no causal effect on dental caries occurrence in the primary dentition. [ABSTRACT FROM AUTHOR]

Published
2024
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175. Trajectory of maternal depression and parasomnias.

Author

Guttier, Marília C., Halal, Camila S., Matijasevich, Alicia, Del‐Ponte, Bianca, Tovo‐Rodrigues, Luciana, Barros, Fernando, Bassani, Diego G., and Santos, Iná S.

Subjects
DEPRESSION in women, PARASOMNIAS, EDINBURGH Postnatal Depression Scale, SLEEP disorders, NIGHT terrors
Abstract

Summary: Maternal depressive symptoms are associated with poorer sleep quality in their children. Although parasomnias can occur at any age, this group of sleep disorders is more common in children. The aim of this study was to assess whether maternal depression trajectories predict parasomnias at the age of 11 years. Data were from a Birth Cohort of 4231 individuals followed in the city of Pelotas, Brazil. Maternal depressive symptoms were assessed with the Edinburgh Postnatal Depression Scale (EPDS) at 12, 24, and 48 months, and 6 and 11 years postpartum. Maternal depression trajectories were calculated using a group‐based modelling approach. Information on any parasomnias (confused arousals, sleepwalking, night terrors, and nightmares) was provided by the mother. Five trajectories of maternal depressive symptoms were identified: chronic‐low (34.9%), chronic‐moderate (41.4%), increasing (10.3%), decreasing (8.9%), and chronic‐high (4.4%). The prevalence of any parasomnia at the age of 11 years was 16.8% (95% confidence interval [CI] 15.6%–18.1%). Confusional arousal was the most prevalent type of parasomnia (14.5%) and varied from 8.7% to 14.7%, 22.9%, 20.3%, and 27.5% among children of mothers at chronic‐low, moderate‐low, increasing, decreasing, and chronic‐high trajectories, respectively (p < 0.001). Compared to children from mothers in the chronic‐low trajectory, the adjusted prevalence ratio for any parasomnia was 1.58 (95% CI 1.29–1.94), 2.34 (95% CI 1.83–2.98), 2.15 (95% CI 1.65–2.81), and 3.07 (95% CI 2.31–4.07) among those from mothers in the moderate‐low, increasing, decreasing, and chronic‐high trajectory groups, respectively (p < 0.001). In conclusion, parasomnias were more prevalent among children of mothers with chronic symptoms of depression. [ABSTRACT FROM AUTHOR]

Published
2024
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176. Cohort Profile Update: 2004 Pelotas (Brazil) Birth Cohort Study follow-up during adolescent years.

Author

Tovo-Rodrigues, Luciana, Santos, Iná S, Bierhals, Isabel Oliveira, Del-Ponte, Bianca, Murray, Joseph, Bielemann, Renata, Munhoz, Tiago N, Crochemore-Silva, Inácio, Oliveira, Isabel O de, Barros, Fernando C, Barros, Aluísio J D, and Matijasevich, Alicia

Subjects
PREMATURE infants, COHORT analysis, BIRTH rate, TEENAGE pregnancy, PLETHYSMOGRAPHY, TEENAGERS, YOUNG adults, COVID-19 pandemic, DUAL-energy X-ray absorptiometry
Abstract

The given text provides a summary of the 2004 Pelotas Birth Cohort Study conducted in Pelotas, Brazil. The study followed 4,231 participants from birth to 17 years of age and collected data on various factors such as mental health, non-communicable diseases, clinical conditions, human capital, violence, and the impact of the COVID-19 pandemic. The study aimed to investigate the impact of early life exposures on health outcomes and social inequities. The text also provides information on the follow-up rates of the study at different time points, with factors such as maternal age, education, smoking, and family income influencing the rates. The study found stable mental health among adolescents, an increase in maternal depression, a decrease in obesity, and an increase in alcohol and cigarette experimentation. The COVID-19 impact study revealed challenges faced by adolescents during the pandemic. The study has strengths in its design and high follow-up rates but has limitations due to the pandemic. The data from the study are available upon request. [Extracted from the article]

Published
2024
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178. Multiple imputation to deal with missing objectively-measured physical activity data: findings from two cohorts

Author

Iná dos Santos, João Pedro Ribeiro, Inácio Crochemore-Silva, Fernando C. Wehrmeister, Bruna Gonçalves Cordeiro da Silva, Alicia Matijasevich, Helen Gonçalves, Shana Ginar da Silva, Luiza Isnardi Cardoso Ricardo, Ana M. B. Menezes, Rafaela Costa Martins, Cauane Blumenberg, Aluísio J D Barros, Martins, Rafaela Costa [0000-0003-3538-7228], Silva, Bruna Gonçalves C da [0000-0003-2917-7320], Blumenberg, Cauane [0000-0002-4580-3849], Ricardo, Luiza Isnardi [0000-0002-1244-4501], Silva, Shana Ginar da [0000-0003-1504-6936], Matijasevich, Alicia [0000-0003-0060-1589], Wehrmeister, Fernando César [0000-0001-7137-1747], Santos, Iná dos [0000-0003-1258-9249], Crochemore-Silva, Inácio [0000-0001-5390-8360], and Apollo - University of Cambridge Repository

Subjects
2 Aetiology, 2.3 Psychological, social and economic factors, business.industry, Physical activity, 42 Health Sciences, Missing data, Oral and gastrointestinal, Clinical Research, Skin color, Statistics, Genetics, 4206 Public Health, Medicine, Animal Science and Zoology, Accelerometer data, business, Birth cohort, Socioeconomic status, Cancer
Abstract

The objective of this article was to describe patterns of losses of information regarding accelerometer data and to assess the use of multiple imputation to generate physical activity estimates for individuals without accelerometry data. Two birth cohort studies from Pelotas (Brazil) with participants aged 22 and 11-years old assessed objectively measured physical activity differences between complete and imputed cases. Mean values of overall physical activity for complete cases (n1993 = 2,985 and n2004 = 3,348) and for complete cases plus imputed cases (n1993 = 760 and n2004 = 79) were described according to predictors. Male individuals, participants with black skin color, and less schooled individuals presented higher averages of overall physical activity than their counterparts. Almost all imputed estimates were comparable to the complete cases, and the highest difference found was 0.7 mg for the first quintile of socioeconomic status of the 1993 birth cohort. Multiple imputation is a positive technique to deal with missing data from objectively measured physical activity. It provides a set of relevant variables to be used in order to efficiently predict accelerometer data.

Published
2023
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180. Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants

Author

Zhou, Bin, Bentham, James, Di Cesare, Mariachiara, Bixby, Honor, Danaei, Goodarz, Cowan, Melanie J, Paciorek, Christopher J, Singh, Gitanjali, Hajifathalian, Kaveh, Bennett, James E, Taddei, Cristina, Bilano, Ver, Carrillo-Larco, Rodrigo M, Djalalinia, Shirin, Khatibzadeh, Shahab, Lugero, Charles, Peykari, Niloofar, Zhang, Wan Zhu, Lu, Yuan, Stevens, Gretchen A, Riley, Leanne M, Bovet, Pascal, Elliott, Paul, Gu, Dongfeng, Ikeda, Nayu, Jackson, Rod T, Joffres, Michel, Kengne, Andre Pascal, Laatikainen, Tiina, Lam, Tai Hing, Laxmaiah, Avula, Liu, Jing, Miranda, J Jaime, Mondo, Charles K, Neuhauser, Hannelore K, Sundström, Johan, Smeeth, Liam, Soric, Maroje, Woodward, Mark, Ezzati, Majid, Abarca-Gómez, Leandra, Abdeen, Ziad A, Rahim, Hanan Abdul, Abu-Rmeileh, Niveen M, Acosta-Cazares, Benjamin, Adams, Robert, Aekplakorn, Wichai, Afsana, Kaosar, Aguilar-Salinas, Carlos A, Agyemang, Charles, Ahmadvand, Alireza, Ahrens, Wolfgang, Al Raddadi, Rajaa, Al Woyatan, Rihab, Ali, Mohamed M, Alkerwi, Ala'a, Aly, Eman, Amouyel, Philippe, Amuzu, Antoinette, Andersen, Lars Bo, Anderssen, Sigmund A, Ängquist, Lars, Anjana, Ranjit Mohan, Ansong, Daniel, Aounallah-Skhiri, Hajer, Araújo, Joana, Ariansen, Inger, Aris, Tahir, Arlappa, Nimmathota, Aryal, Krishna, Arveiler, Dominique, Assah, Felix K, Assunção, Maria Cecília F, Avdicová, Mária, Azevedo, Ana, Azizi, Fereidoun, Babu, Bontha V, Bahijri, Suhad, Balakrishna, Nagalla, Bandosz, Piotr, Banegas, José R, Barbagallo, Carlo M, Barceló, Alberto, Barkat, Amina, Barros, Aluisio J D, Barros, Mauro V, Bata, Iqbal, Batieha, Anwar M, Baur, Louise A, Beaglehole, Robert, Romdhane, Habiba Ben, Benet, Mikhail, Benson, Lowell S, Bernabe-Ortiz, Antonio, Bernotiene, Gailute, Bettiol, Heloisa, Bhagyalaxmi, Aroor, Bharadwaj, Sumit, Bhargava, Santosh K, Bi, Yufang, Bikbov, Mukharram, Bjerregaard, Peter, Bjertness, Espen, Björkelund, Cecilia, Blokstra, Anneke, Bo, Simona, Bobak, Martin, Boeing, Heiner, Boggia, Jose G, Boissonnet, Carlos P, Bongard, Vanina, Braeckman, Lutgart, Brajkovich, Imperia, Branca, Francesco, Breckenkamp, Juergen, Brenner, Hermann, Brewster, Lizzy M, Bruno, Graziella, Bueno-de-Mesquita, H B(as), Bugge, Anna, Burns, Con, Bursztyn, Michael, de León, Antonio Cabrera, Cacciottolo, Joseph, Cameron, Christine, Can, Günay, Cândido, Ana Paula C, Capuano, Vincenzo, Cardoso, Viviane C, Carlsson, Axel C, Carvalho, Maria J, Casanueva, Felipe F, Casas, Juan-Pablo, Caserta, Carmelo A, Chamukuttan, Snehalatha, Chan, Angelique W, Chan, Queenie, Chaturvedi, Himanshu K, Chaturvedi, Nishi, Chen, Chien-Jen, Chen, Fangfang, Chen, Huashuai, Chen, Shuohua, Chen, Zhengming, Cheng, Ching-Yu, Dekkaki, Imane Cherkaoui, Chetrit, Angela, Chiolero, Arnaud, Chiou, Shu-Ti, Chirita-Emandi, Adela, Cho, Belong, Cho, Yumi, Chudek, Jerzy, Cifkova, Renata, Claessens, Frank, Clays, Els, Concin, Hans, Cooper, Cyrus, Cooper, Rachel, Coppinger, Tara C, Costanzo, Simona, Cottel, Dominique, Cowell, Chris, Craig, Cora L, Crujeiras, Ana B, Cruz, Juan J, D'Arrigo, Graziella, d'Orsi, Eleonora, Dallongeville, Jean, Damasceno, Albertino, Dankner, Rachel, Dantoft, Thomas M, Dauchet, Luc, De Backer, Guy, De Bacquer, Dirk, de Gaetano, Giovanni, De Henauw, Stefaan, De Smedt, Delphine, Deepa, Mohan, Dehghan, Abbas, Delisle, Hélène, Deschamps, Valérie, Dhana, Klodian, Di Castelnuovo, Augusto F, Dias-da-Costa, Juvenal Soares, Diaz, Alejandro, Dickerson, Ty T, Do, Ha T P, Dobson, Annette J, Donfrancesco, Chiara, Donoso, Silvana P, Döring, Angela, Doua, Kouamelan, Drygas, Wojciech, Dulskiene, Virginija, Džakula, Aleksandar, Dzerve, Vilnis, Dziankowska-Zaborszczyk, Elzbieta, Eggertsen, Robert, Ekelund, Ulf, El Ati, Jalila, Ellert, Ute, Elosua, Roberto, Erasmus, Rajiv T, Erem, Cihangir, Eriksen, Louise, de la Peña, Jorge Escobedo, Evans, Alun, Faeh, David, Fall, Caroline H, Farzadfar, Farshad, Felix-Redondo, Francisco J, Ferguson, Trevor S, Fernández-Bergés, Daniel, Ferrante, Daniel, Ferrari, Marika, Ferreccio, Catterina, Ferrieres, Jean, Finn, Joseph D, Fischer, Krista, Föger, Bernhard, Foo, Leng Huat, Forslund, Ann-Sofie, Forsner, Maria, Fortmann, Stephen P, Fouad, Heba M, Francis, Damian K, Franco, Maria do Carmo, Franco, Oscar H, Frontera, Guillermo, Fuchs, Flavio D, Fuchs, Sandra C, Fujita, Yuki, Furusawa, Takuro, Gaciong, Zbigniew, Gareta, Dickman, Garnett, Sarah P, Gaspoz, Jean-Michel, Gasull, Magda, Gates, Louise, Gavrila, Diana, Geleijnse, Johanna M, Ghasemian, Anoosheh, Ghimire, Anup, Giampaoli, Simona, Gianfagna, Francesco, Giovannelli, Jonathan, Goldsmith, Rebecca A, Gonçalves, Helen, Gross, Marcela Gonzalez, Rivas, Juan P González, Gottrand, Frederic, Graff-Iversen, Sidsel, Grafnetter, Dušan, Grajda, Aneta, Gregor, Ronald D, Grodzicki, Tomasz, Grøntved, Anders, Gruden, Grabriella, Grujic, Vera, Guan, Ong Peng, Gudnason, Vilmundur, Guerrero, Ramiro, Guessous, Idris, Guimaraes, Andre L, Gulliford, Martin C, Gunnlaugsdottir, Johanna, Gunter, Marc, Gupta, Prakash C, Gureje, Oye, Gurzkowska, Beata, Gutierrez, Laura, Gutzwiller, Felix, Hadaegh, Farzad, Halkjær, Jytte, Hambleton, Ian R, Hardy, Rebecca, Harikumar, Rachakulla, Hata, Jun, Hayes, Alison J, He, Jiang, Hendriks, Marleen Elisabeth, Henriques, Ana, Cadena, Leticia Hernandez, Herrala, Sauli, Heshmat, Ramin, Hihtaniemi, Ilpo Tapani, Ho, Sai Yin, Ho, Suzanne C, Hobbs, Michael, Hofman, Albert, Dinc, Gonul Horasan, Hormiga, Claudia M, Horta, Bernardo L, Houti, Leila, Howitt, Christina, Htay, Thein Thein, Htet, Aung Soe, Hu, Yonghua, Huerta, José María, Husseini, Abdullatif S, Huybrechts, Inge, Hwalla, Nahla, Iacoviello, Licia, Iannone, Anna G, Ibrahim, M Mohsen, Ikram, M Arfan, Irazola, Vilma E, Islam, Muhammad, Ivkovic, Vanja, Iwasaki, Masanori, Jacobs, Jeremy M, Jafar, Tazeen, Jamrozik, Konrad, Janszky, Imre, Jasienska, Grazyna, Jelakovic, Bojan, Jiang, Chao Qiang, Johansson, Mattias, Jonas, Jost B, Jørgensen, Torben, Joshi, Pradeep, Juolevi, Anne, Jurak, Gregor, Jureša, Vesna, Kaaks, Rudolf, Kafatos, Anthony, Kalter-Leibovici, Ofra, Kamaruddin, Nor Azmi, Kasaeian, Amir, Katz, Joanne, Kauhanen, Jussi, Kaur, Prabhdeep, Kavousi, Maryam, Kazakbaeva, Gyulli, Keil, Ulrich, Boker, Lital Keinan, Keinänen-Kiukaanniemi, Sirkka, Kelishadi, Roya, Kemper, Han C G, Kersting, Mathilde, Key, Timothy, Khader, Yousef Saleh, Khalili, Davood, Khang, Young-Ho, Khaw, Kay-Tee, Kiechl, Stefan, Killewo, Japhet, Kim, Jeongseon, Klumbiene, Jurate, Kolle, Elin, Kolsteren, Patrick, Korrovits, Paul, Koskinen, Seppo, Kouda, Katsuyasu, Koziel, Slawomir, Kristensen, Peter Lund, Krokstad, Steinar, Kromhout, Daan, Kruger, Herculina S, Kubinova, Ruzena, Kuciene, Renata, Kuh, Diana, Kujala, Urho M, Kula, Krzysztof, Kulaga, Zbigniew, Kumar, R Krishna, Kurjata, Pawel, Kusuma, Yadlapalli S, Kuulasmaa, Kari, Kyobutungi, Catherine, Lachat, Carl, Landrove, Orlando, Lanska, Vera, Lappas, Georg, Larijani, Bagher, Laugsand, Lars E, Bao, Khanh Le Nguyen, Le, Tuyen D, Leclercq, Catherine, Lee, Jeannette, Lee, Jeonghee, Lehtimäki, Terho, Lekhraj, Rampal, León-Muñoz, Luz M, Levitt, Naomi S, Li, Yanping, Lilly, Christa L, Lim, Wei-Yen, Lima-Costa, M Fernanda, Lin, Hsien-Ho, Lin, Xu, Linneberg, Allan, Lissner, Lauren, Litwin, Mieczyslaw, Lorbeer, Roberto, Lotufo, Paulo A, Lozano, José Eugenio, Luksiene, Dalia, Lundqvist, Annamari, Lunet, Nuno, Lytsy, Per, Ma, Guansheng, Ma, Jun, Machado-Coelho, George L L, Machi, Suka, Maggi, Stefania, Magliano, Dianna J, Majer, Marjeta, Makdisse, Marcia, Malekzadeh, Reza, Malhotra, Rahul, Rao, Kodavanti Mallikharjuna, Malyutina, Sofia, Manios, Yannis, Mann, Jim I, Manzato, Enzo, Margozzini, Paula, Marques-Vidal, Pedro, Marrugat, Jaume, Martorell, Reynaldo, Mathiesen, Ellisiv B, Matijasevich, Alicia, Matsha, Tandi E, Mbanya, Jean Claude N, Posso, Anselmo J Mc Donald, McFarlane, Shelly R, McGarvey, Stephen T, McLachlan, Stela, McLean, Rachael M, McNulty, Breige A, Khir, Amir Sharifuddin Md, Mediene-Benchekor, Sounnia, Medzioniene, Jurate, Meirhaeghe, Aline, Meisinger, Christa, Menezes, Ana Maria B, Menon, Geetha R, Meshram, Indrapal I, Metspalu, Andres, Mi, Jie, Mikkel, Kairit, Miller, Jody C, Miquel, Juan Francisco, Mišigoj-Durakovic, Marjeta, Mohamed, Mostafa K, Mohammad, Kazem, Mohammadifard, Noushin, Mohan, Viswanathan, Yusoff, Muhammad Fadhli Mohd, Møller, Niels C, Molnár, Dénes, Momenan, Amirabbas, Monyeki, Kotsedi Daniel K, Moreira, Leila B, Morejon, Alain, Moreno, Luis A, Morgan, Karen, Moschonis, George, Mossakowska, Malgorzata, Mostafa, Aya, Mota, Jorge, Motlagh, Mohammad Esmaeel, Motta, Jorge, Muiesan, Maria L, Müller-Nurasyid, Martina, Murphy, Neil, Mursu, Jaakko, Musil, Vera, Nagel, Gabriele, Naidu, Balkish M, Nakamura, Harunobu, Námešná, Jana, Nang, Ei Ei K, Nangia, Vinay B, Narake, Sameer, Navarrete-Muñoz, Eva Maria, Ndiaye, Ndeye Coumba, Neal, William A, Nenko, Ilona, Nervi, Flavio, Nguyen, Nguyen D, Nguyen, Quang Ngoc, Nieto-Martínez, Ramfis E, Niiranen, Teemu J, Ning, Guang, Ninomiya, Toshiharu, Nishtar, Sania, Noale, Marianna, Noboa, Oscar A, Noorbala, Ahmad Ali, Noorbala, Teresa, Noto, Davide, Al Nsour, Mohannad, O'Reilly, Dermot, Oh, Kyungwon, Olinto, Maria Teresa A, Oliveira, Isabel O, Omar, Mohd Azahadi, Onat, Altan, Ordunez, Pedro, Osmond, Clive, Ostojic, Sergej M, Otero, Johanna A, Overvad, Kim, Owusu-Dabo, Ellis, Paccaud, Fred Michel, Padez, Cristina, Pahomova, Elena, Pajak, Andrzej, Palli, Domenico, Palmieri, Luigi, Panda-Jonas, Songhomitra, Panza, Francesco, Papandreou, Dimitrios, Parnell, Winsome R, Parsaeian, Mahboubeh, Pecin, Ivan, Pednekar, Mangesh S, Peer, Nasheeta, Peeters, Petra H, Peixoto, Sergio Viana, Pelletier, Catherine, Peltonen, Markku, Pereira, Alexandre C, Pérez, Rosa Marina, Peters, Annette, Petkeviciene, Janina, Pham, Son Thai, Pigeot, Iris, Pikhart, Hynek, Pilav, Aida, Pilotto, Lorenza, Pitakaka, Freda, Plans-Rubió, Pedro, Polakowska, Maria, Polašek, Ozren, Porta, Miquel, Portegies, Marileen LP, Pourshams, Akram, Pradeepa, Rajendra, Prashant, Mathur, Price, Jacqueline F, Puiu, Maria, Punab, Margus, Qasrawi, Radwan F, Qorbani, Mostafa, Radic, Ivana, Radisauskas, Ricardas, Rahman, Mahfuzar, Raitakari, Olli, Raj, Manu, Rao, Sudha Ramachandra, Ramachandran, Ambady, Ramos, Elisabete, Rampal, Sanjay, Reina, Daniel A Rangel, Rasmussen, Finn, Redon, Josep, Reganit, Paul Ferdinand M, Ribeiro, Robespierre, Riboli, Elio, Rigo, Fernando, de Wit, Tobias F Rinke, Ritti-Dias, Raphael M, Robinson, Sian M, Robitaille, Cynthia, Rodríguez-Artalejo, Fernando, Rodriguez-Perez del Cristo, María, Rodríguez-Villamizar, Laura A, Rojas-Martinez, Rosalba, Rosengren, Annika, Rubinstein, Adolfo, Rui, Ornelas, Ruiz-Betancourt, Blanca Sandra, Horimoto, Andrea R V Russo, Rutkowski, Marcin, Sabanayagam, Charumathi, Sachdev, Harshpal S, Saidi, Olfa, Sakarya, Sibel, Salanave, Benoit, Salazar Martinez, Eduardo, Salmerón, Diego, Salomaa, Veikko, Salonen, Jukka T, Salvetti, Massimo, Sánchez-Abanto, Jose, Sans, Susana, Santos, Diana, Santos, Ina S, dos Santos, Renata Nunes, Santos, Rute, Saramies, Jouko L, Sardinha, Luis B, Margolis, Giselle Sarganas, Sarrafzadegan, Nizal, Saum, Kai-Uwe, Savva, Savvas C, Scazufca, Marcia, Schargrodsky, Herman, Schneider, Ione J, Schultsz, Constance, Schutte, Aletta E, Sen, Abhijit, Senbanjo, Idowu O, Sepanlou, Sadaf G, Sharma, Sanjib K, Shaw, Jonathan E, Shibuya, Kenji, Shin, Dong Wook, Shin, Youchan, Siantar, Rosalynn, Sibai, Abla M, Silva, Diego Augusto Santos, Simon, Mary, Simons, Judith, Simons, Leon A, Sjöström, Michael, Skovbjerg, Sine, Slowikowska-Hilczer, Jolanta, Slusarczyk, Przemyslaw, Smith, Margaret C, Snijder, Marieke B, So, Hung-Kwan, Sobngwi, Eugène, Söderberg, Stefan, Solfrizzi, Vincenzo, Sonestedt, Emily, Song, Yi, Sørensen, Thorkild IA, Jérome, Charles Sossa, Soumare, Aicha, Staessen, Jan A, Starc, Gregor, Stathopoulou, Maria G, Stavreski, Bill, Steene-Johannessen, Jostein, Stehle, Peter, Stein, Aryeh D, Stergiou, George S, Stessman, Jochanan, Stieber, Jutta, Stöckl, Doris, Stocks, Tanja, Stokwiszewski, Jakub, Stronks, Karien, Strufaldi, Maria Wany, Sun, Chien-An, Sung, Yn-Tz, Suriyawongpaisal, Paibul, Sy, Rody G, Tai, E Shyong, Tammesoo, Mari-Liis, Tamosiunas, Abdonas, Tang, Line, Tang, Xun, Tanser, Frank, Tao, Yong, Tarawneh, Mohammed Rasoul, Tarqui-Mamani, Carolina B, Taylor, Anne, Theobald, Holger, Thijs, Lutgarde, Thuesen, Betina H, Tjonneland, Anne, Tolonen, Hanna K, Tolstrup, Janne S, Topbas, Murat, Topór-Madry, Roman, Tormo, María José, Torrent, Maties, Traissac, Pierre, Trichopoulos, Dimitrios, Trichopoulou, Antonia, Trinh, Oanh T H, Trivedi, Atul, Tshepo, Lechaba, Tulloch-Reid, Marshall K, Tuomainen, Tomi-Pekka, Tuomilehto, Jaakko, Turley, Maria L, Tynelius, Per, Tzourio, Christophe, Ueda, Peter, Ugel, Eunice, Ulmer, Hanno, Uusitalo, Hannu M T, Valdivia, Gonzalo, Valvi, Damaskini, van der Schouw, Yvonne T, Van Herck, Koen, van Rossem, Lenie, van Valkengoed, Irene GM, Vanderschueren, Dirk, Vanuzzo, Diego, Vatten, Lars, Vega, Tomas, Velasquez-Melendez, Gustavo, Veronesi, Giovanni, Verschuren, W M Monique, Verstraeten, Roosmarijn, Victora, Cesar G, Viet, Lucie, Viikari-Juntura, Eira, Vineis, Paolo, Vioque, Jesus, Virtanen, Jyrki K, Visvikis-Siest, Sophie, Viswanathan, Bharathi, Vollenweider, Peter, Voutilainen, Sari, Vrdoljak, Ana, Vrijheid, Martine, Wade, Alisha N, Wagner, Aline, Walton, Janette, Mohamud, Wan Nazaimoon Wan, Wang, Ming-Dong, Wang, Qian, Wang, Ya Xing, Wannamethee, S Goya, Wareham, Nicholas, Wedderkopp, Niels, Weerasekera, Deepa, Whincup, Peter H, Widhalm, Kurt, Widyahening, Indah S, Wiecek, Andrzej, Wijga, Alet H, Wilks, Rainford J, Willeit, Johann, Willeit, Peter, Williams, Emmanuel A, Wilsgaard, Tom, Wojtyniak, Bogdan, Wong, Tien Yin, Wong-McClure, Roy A, Woo, Jean, Wu, Aleksander Giwercman, Wu, Frederick C, Wu, Shou Ling, Xu, Haiquan, Yan, Weili, Yang, Xiaoguang, Ye, Xingwang, Yiallouros, Panayiotis K, Yoshihara, Akihiro, Younger-Coleman, Novie O, Yusoff, Ahmad F, Yusoff, Muhammad Fadhli M, Zambon, Sabina, Zdrojewski, Tomasz, Zeng, Yi, Zhao, Dong, Zhao, Wenhua, Zheng, Yingffeng, Zhu, Dan, Zimmermann, Esther, and Zuñiga Cisneros, Julio

Published
2017
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183. Repeat cesarean section in subsequent gestation of women from a birth cohort in Brazil

Author

Keila Cristina Mascarello, Alicia Matijasevich, Aluísio J D Barros, Iná S Santos, Eliana Zandonade, and Mariângela Freitas Silveira

Subjects
Cesarean section, Natural childbirth, Trial of labor, Gynecology and obstetrics, RG1-991
Abstract

Abstract Background The current literature indicates increasing concern regarding the number of safe cesarean sections which a woman can undergo, mainly in face of the high cesarean section rates, which are growing in Brazil and worldwide. Aimed to describe the prevalence and associated factors of repeat cesarean section in a cohort of Brazilian women who had a cesarean section in the first birth. Methods This is a prospective cohort study using data from the 2004 Pelotas Birth Cohort. The sample included 480 women who had their first delivery in 2004, regardless of the form of delivery, and who had a second delivery identified in the cohort’s follow-ups (in 2005, 2006, 2008, and 2010). Descriptive, bivariate and multivariate analyses using Poisson regression with robust error variance were carried out. Results Among the women who underwent a cesarean section in their first delivery (49.47%), 87.44% had a second surgical delivery. The risk factors for repeat cesarean section included ages 21–34 (PR 1.67, CI 95% 1.07–2.60), not being seen by SUS (Public Healthcare System) in 2004 (PR 2.27, CI 95% 1.44–3.60), and the number of prenatal medical visits, i.e., women with ten or more visits were at 2.33 times higher risk (CI 95% 1.10–4.96) compared to those who had five or fewer visits. Conclusions The proportion of cesarean sections both in the first and in the subsequent delivery is quite high. This high rate may compromise the reproductive future of the women who undergo consecutive cesarean sections with possible consequent complications and changes in care policies for pregnant women should be implemented.

Published
2017
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184. Caesarean section and adiposity at 6, 18 and 30 years of age: results from three Pelotas (Brazil) birth cohorts

Author

Aluisio J. D. Barros, Leonardo Pozza Santos, Fernando Wehrmeister, Janaina Vieira dos Santos Motta, Alicia Matijasevich, Ina S. Santos, Ana M. B. Menezes, Helen Gonçalves, Maria Cecília Formoso Assunção, Bernardo L. Horta, and Fernando C. Barros

Subjects
Cesarean section, Body composition, Adiposity, Cohort studies, Public aspects of medicine, RA1-1270
Abstract

Abstract Background Association between caesarian section (C-section) and obesity is controversial and mostly based on body mass index (BMI), which has inherent limitations. Using direct estimates of body fat mass, we aimed to assess the association between C-section and adiposity using fat mass index and BMI z-score in three birth cohort studies from Pelotas, Brazil. Methods We measured weight, height and fat mass (using dual X-ray absorptiometry (DXA)) at ages 6, 18 and 30 years among participants in the 2004, 1993 and 1982 population-based Pelotas Birth Cohort Studies, respectively. We used multiple linear regression analysis to examine the crude and adjusted association between C-section and the body composition indicators. We also modelled height as an outcome to explore the presence of residual confounding. Results We observed that fat mass index and BMI z-score were strongly and positively associated with C-section in the crude analysis. However, when we adjusted for socioeconomic characteristics, maternal BMI, parity, age and smoking during pregnancy, effect estimates were attenuated towards the null, except for 30-year-old women. In those women from the 1982 cohort, C-section remained associated with fat mass index (β = 0.82; CI95% 0.32;1.32) and BMI z-score (β = 0.15; CI95% 0.03;0.28), even after adjusting for all potential confounders, suggesting an increase in fat mass index and BMI at 30 years among those born by C-section. Conclusion We found no consistent association of C-section with fat mass index measured by DXA and BMI z-score in individuals aged 6, 18 and 30 years, except for women in the latter group, which might be explained by residual confounding. Confounding by socioeconomic and maternal characteristics accounted for all the other associations.

Published
2017
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186. Fetal growth velocity standards from the Fetal Growth Longitudinal Study of the INTERGROWTH-21st Project

Author

Katz, M., Bhan, M.K., Garza, C., Zaidi, S., Langer, A., Rothwell, P.M., Weatherall, Sir D., Bhutta, Z.A., Villar, J., Kennedy, S., Altman, D.G., Barros, F.C., Bertino, E., Burton, F., Carvalho, M., Cheikh Ismail, L., Chumlea, W.C., Gravett, M.G., Jaffer, Y.A., Lambert, A., Lumbiganon, P., Noble, J.A., Pang, R.Y., Papageorghiou, A.T., Purwar, M., Rivera, J., Victora, C., Shorten, M., Hoch, L., Knight, H.E., Ohuma, E.O., Cosgrove, C., Blakey, I., Roseman, F., Kunnawar, N., Gu, S.H., Wang, J.H., Wu, M.H., Domingues, M., Gilli, P., Juodvirsiene, L., Musee, N., Al-Jabri, H., Waller, S., Muninzwa, D., Yellappan, D., Carter, A., Reade, D., Miller, R., Salomon, L., Leston, A., Mitidieri, A., Al-Aamri, F., Paulsene, W., Sande, J., Al-Zadjali, W.K.S., Batiuk, C., Bornemeier, S., Dighe, M., Gaglioti, P., Jacinta, N., Jaiswal, S., Oas, K., Oberto, M., Olearo, E., Owende, M.G., Shah, J., Sohoni, S., Todros, T., Venkataraman, M., Vinayak, S., Wang, L., Wilson, D., Wu, Q.Q., Zhang, Y., Chamberlain, P., Danelon, D., Sarris, I., Dhami, J., Ioannou, C., Knight, C.L., Napolitano, R., Wanyonyi, S., Pace, C., Mkrtychyan, V., Al-Habsi, F., Alija, M., Jimenez-Bustos, J.M., Kizidio, J., Puglia, F., Liu, H., Lloyd, S., Mota, D., Ochieng, R., Rossi, C., Sanchez Luna, M., Shen, Y.J., Rocco, D.A., Frederick, I.O., Albernaz, E., Batra, M., Bhat, B.A., Di Nicola, P., Giuliani, F., Rovelli, I., McCormick, K., Paul, V., Rajan, V., Wilkinson, A., Varalda, A., Eskenazi, B., Corra, L.A., Dolk, H., Golding, J., Matijasevich, A., de Wet, T., Zhang, J.J., Bradman, A., Finkton, D., Burnham, O., Farhi, F., Fonseca, S., Sclowitz, I.K., da Silveira, M.F., He, Y.P., Pan, Y., Yuan, Y., Choudhary, A., Choudhary, S., Deshmukh, S., Dongaonkar, D., Ketkar, M., Khedikar, V., Mahorkar, C., Mulik, I., Saboo, K., Shembekar, C., Singh, A., Taori, V., Tayade, K., Somani, A., Frigerio, M., Gilli, G., Giolito, M., Occhi, L., Signorile, F., Stones, W., Kisiang’ani, C., Al-Abri, J., Al-Abduwani, J., Al-Habsi, F.M., Al-Lawatiya, H., Al-Rashidiya, B., Juangco, F.R., Andersen, H.F., Abbott, S.E., Carter, A.A., Algren, H., Sorensen, T.K., Enquobahrie, D., Ohuma, Eric O., Villar, José, Feng, Yuan, Xiao, Luo, Salomon, Laurent, Barros, Fernando C., Cheikh Ismail, Leila, Stones, William, Jaffer, Yasmin, Oberto, Manuela, Noble, J. Alison, Gravett, Michael G., Wu, Qingqing, Victora, Cesar G., Lambert, Ann, Di Nicola, Paola, Purwar, Manorama, Bhutta, Zulfiqar A., Kennedy, Stephen H., and Papageorghiou, Aris T.

Published
2021
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188. Early life risk factors of motor, cognitive and language development: a pooled analysis of studies from low/middle-income countries

Author

Aluísio J D Barros, Günther Fink, Goodarz Danaei, Christopher R Sudfeld, Rose McGready, Nynke van den Broek, Joseph M Braun, Karim Manji, Shams E Arifeen, Melissa Gladstone, Jena Hamadani, Fahmida Tofail, Alicia Matijasevich, Sunita Taneja, Honorati Masanja, Wafaie Fawzi, Ayesha Sania, Dana C McCoy, Zhaozhong Zhu, Mary C Smith Fawzi, Mehmet Akman, David Bellinger, Maureen M Black, Alemtsehay Bogale, Verena Carrara, Paulita Duazo, Christopher Duggan, Lia C H Fernald, Alexis J Handal, Siobán Harlow, Melissa Hidrobo, Chris Kuzawa, Ingrid Kvestad, Lindsey Locks, Christine McDonald, Arjumand Rizvi, Darci Santos, Leticia Santos, Dilsad Save, Roger Shapiro, Barbara Stoecker, Martha-Maria Tellez-Rojo, and Aisha K Yousafzai

Subjects
Medicine
Abstract

Objective To determine the magnitude of relationships of early life factors with child development in low/middle-income countries (LMICs).Design Meta-analyses of standardised mean differences (SMDs) estimated from published and unpublished data.Data sources We searched Medline, bibliographies of key articles and reviews, and grey literature to identify studies from LMICs that collected data on early life exposures and child development. The most recent search was done on 4 November 2014. We then invited the first authors of the publications and investigators of unpublished studies to participate in the study.Eligibility criteria for selecting studies Studies that assessed at least one domain of child development in at least 100 children under 7 years of age and collected at least one early life factor of interest were included in the study.Analyses Linear regression models were used to assess SMDs in child development by parental and child factors within each study. We then produced pooled estimates across studies using random effects meta-analyses.Results We retrieved data from 21 studies including 20 882 children across 13 LMICs, to assess the associations of exposure to 14 major risk factors with child development. Children of mothers with secondary schooling had 0.14 SD (95% CI 0.05 to 0.25) higher cognitive scores compared with children whose mothers had primary education. Preterm birth was associated with 0.14 SD (–0.24 to –0.05) and 0.23 SD (–0.42 to –0.03) reductions in cognitive and motor scores, respectively. Maternal short stature, anaemia in infancy and lack of access to clean water and sanitation had significant negative associations with cognitive and motor development with effects ranging from −0.18 to −0.10 SDs.Conclusions Differential parental, environmental and nutritional factors contribute to disparities in child development across LMICs. Targeting these factors from prepregnancy through childhood may improve health and development of children.

Published
2019
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189. Gestational diabetes mellitus, pre-gestational BMI and offspring BMI z-score during infancy and childhood: 2004 Pelotas Birth Cohort

Author

Aluísio J D Barros, Iná S Santos, Alicia Matijasevich, and Christian Loret de Mola

Subjects
Medicine
Abstract

Objective Gestational diabetes mellitus (GDM) affects a significant number of women. Evidence regarding the association between GDM and offspring body mass index (BMI) is unclear due to small samples and lack of adequate confounding control. The objective of this study was to investigate the association between GDM and offspring BMI z-scores from birth to early adolescence and to examine the role of maternal pre-gestational BMI in this relationship.Design Prospective study.Setting Pelotas 2004 Birth Cohort, Brazil.Participants Cohort participants that were followed-up from birth up to early adolescence (~3500) and their mothers.Primary outcome measures BMI z-scores at birth, 3, 12, 24, 48 months and 6 and 11 years of age, calculated according to the WHO growth charts.Results Unadjusted and adjusted linear regressions were performed and interaction terms between maternal pre-gestational BMI and GDM were included. Prevalence of self-reported GDM was 2.6% (95% CI 2.1% to 3.1%). The offspring BMI z-scores (SD) at birth, 3, 12, 24, 48 months and at 6 and 11 years were 0.10 (1.12), –0.47 (1.10), 0.59 (1.10), 0.59 (1.08), 0.78 (1.32), 0.70 (1.43) and 0.75 (1.41), respectively. Unadjusted regression models showed positive associations between GDM and offspring BMI z-scores at birth, 6 and 11 years. After adjustment, the associations attenuated towards the null. Statistical evidence of effect modification between maternal pre-gestational BMI and GDM was observed at birth (p=0.007), with the association between GDM and offspring BMI z-score being apparent only in those children born to overweight or obese mothers (β=0.72, 95% CI 0.30 to 1.14 and β=0.61, 95% CI 0.20 to 1.01, respectively).Conclusions We observed that in the association between GDM and offspring BMI z-scores, there is a predominant role for maternal nutritional status before pregnancy and that the association between GDM and newborn’s BMI is apparent only among those born to overweight or obese mothers.

Published
2019
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190. Mortalidade no primeiro dia de vida: tendências, causas de óbito e evitabilidade em oito Unidades da Federação brasileira, entre 2010 e 2015

Author

João Alexandre Mendes Teixeira, Waleska Regina Machado Araujo, Ana Goretti Kalume Maranhão, Juan José Cortez-Escalante, Leandro Fórnias Machado de Rezende, and Alicia Matijasevich

Subjects
Infant Mortality, Causes of Death, Child Health, Information Systems, Vital Statistics, Medicine, Public aspects of medicine, RA1-1270
Abstract

Resumo Objetivo: calcular taxas de mortalidade no primeiro dia de vida entre 2010 e 2015 em oito Unidades da Federação brasileira com melhor qualidade de informação, avaliar fatores associados e classificar os óbitos segundo causa básica e evitabilidade. Métodos: estudo descritivo; as taxas foram comparadas conforme características maternas e da criança; a análise de evitabilidade usou a ‘Lista brasileira de causas de mortes evitáveis’. Resultados: 21,6% (n=20.791) dos óbitos infantis ocorreram no primeiro dia de vida; a taxa de mortalidade reduziu-se de 2,7 para 2,3 óbitos/1.000 nascidos vivos; observaram-se maiores taxas em NV com baixo peso, nascidos pré-termo e filhos de mães sem escolaridade; as principais causas dos óbitos foram síndrome da angústia respiratória (8,9%) e imaturidade extrema (5,2%); 66,3% das causas de óbito foram consideradas evitáveis. Conclusão: dois terços dos óbitos no primeiro dia de vida poderiam ser evitados por atenção adequada à mulher na gestação e no parto, e ao NV.

Published
2019
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193. Sex Differences in the Association between Foetal Growth and Child Attention at Age Four: Specific Vulnerability of Girls

Author

Murray, Elizabeth, Matijasevich, Alicia, Santos, Iná S., Barros, Aluísio J. D., Anselmi, Luciana, Barros, Fernando C., and Stein, Alan

Abstract

Background: Recent evidence suggests that impaired foetal growth may provide an early indication of increased risk of child attention problems. However, despite both foetal growth and child attention problems differing by sex, few studies have examined sex differences in this association. Furthermore, no studies have been conducted in low- and middle-income countries, where there are higher rates of perinatal problems. This study aimed to test for sex differences in the association between foetal growth indices and attention problems at age four, in a large, prospective birth cohort from a middle-income country. Methods: A total of 3,749 neonates from the 2004 Pelotas birth cohort (Brazil) with foetal growth indices collected at birth [low birthweight (LBW), small-for-gestational age (SGA), head circumference (HC), head circumference-to-abdominal circumference ratio (HC/AC) and ponderal index (PI)], were assessed for attention problems using the Child Behaviour Checklist at age four. Ordinal logistic regression with successive adjustment for maternal, demographic, gestational, perinatal and child nutrition/mother-child morbidity, was conducted separately for girls and boys. Results: In girls, attention difficulties were associated with being born SGA (OR = 1.40, CI = 1.08-1.82, p = 0.012), with a small HC (OR = 1.52, CI = 1.11-2.08, p = 0.009), or with a low PI (OR = 1.29, CI = 1.08-1.54, p = 0.005). There were no associations identified between attention difficulties and any foetal growth indices in boys. Conclusions: Our results show that girls with impaired foetal growth may be particularly at risk of attention difficulties in childhood. This is consistent with emerging research that female foetuses may be more vulnerable to certain suboptimal intrauterine environments, inducing epigenetic changes that lead to disturbed growth and long-term developmental impairment.

Published
2015
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194. Perinatal and Sociodemographic Factors at Birth Predicting Conduct Problems and Violence to Age 18 Years: Comparison of Brazilian and British Birth Cohorts

Author

Murray, Joseph, Maughan, Barbara, Menezes, Ana M. B., Hickman, Matthew, MacLeod, John, Matijasevich, Alicia, Gonçalves, Helen, Anselmi, Luciana, Gallo, Erika A. G., and Barros, Fernando C.

Abstract

Background: Many low- and middle-income countries have high levels of violence. Research in high-income countries shows that risk factors in the perinatal period are significant precursors of conduct problems which can develop into violence. It is not known whether the same early influences are important in lower income settings with higher rates of violence. This study compared perinatal and sociodemographic risk factors between Brazil and Britain, and their role in explaining higher rates of conduct problems and violence in Brazil. Methods: Prospective population-based birth cohort studies were conducted in Pelotas, Brazil (N = 3,618) and Avon, Britain (N = 4,103). Eleven perinatal and sociodemographic risk factors were measured in questionnaires completed by mothers during the perinatal period. Conduct problems were measured in questionnaires completed by mothers at age 11, and violence in self-report questionnaires completed by adolescents at age 18. Results: Conduct problems were predicted by similar risk factors in Brazil and Britain. Female violence was predicted by several of the same risk factors in both countries. However, male violence in Brazil was associated with only one risk factor, and several risk factor associations were weaker in Brazil than in Britain for both females and males. Almost 20% of the higher risk for conduct problems in Brazil compared to Britain was explained by differential exposure to risk factors. The percentage of the cross-national difference in violence explained by early risk factors was 15% for females and 8% for males. Conclusions: A nontrivial proportion of cross-national differences in antisocial behaviour are related to perinatal and sociodemographic conditions at the start of life. However, risk factor associations are weaker in Brazil than in Britain, and influences in other developmental periods are probably of particular importance for understanding male youth violence in Brazil.

Published
2015
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195. Social communication therapy for children at risk for neurodevelopmental difficulties: Protocol for a clinical trial

Author

Godoy, P, Shephard, E, Argeu, A, Silveira, L, Salomone, E, Aldred, C, Green, J, Polanczyk, G, Matijasevich, A, Godoy P. B. G., Shephard E., Argeu A., Silveira L. R., Salomone E., Aldred C., Green J., Polanczyk G. V., Matijasevich A., Godoy, P, Shephard, E, Argeu, A, Silveira, L, Salomone, E, Aldred, C, Green, J, Polanczyk, G, Matijasevich, A, Godoy P. B. G., Shephard E., Argeu A., Silveira L. R., Salomone E., Aldred C., Green J., Polanczyk G. V., and Matijasevich A.

Abstract

Exposure to adverse environments are risk factors for neurodevelopmental problems in childhood. Children exposed to such environments may benefit from interventions that target social communication abilities, since these are protective factors for healthy neurodevelopment. This randomized controlled trial will test the efficacy of Paediatric Autism Communication Therapy (PACT) in improving social communication development in young children at risk for neurodevelopmental difficulties living in poverty in Brazil. Participants will be 160 children aged 2–4 years with lower-than-average social communication abilities and their primary caregivers. Child–caregiver dyads will be recruited from public childhood education centers in impoverished urban regions of the city of São Paulo, Brazil. Lower-than-average social communication abilities will be defined by standard scores (≤84) on the socialization and/or communication domains of the Vineland Adaptive Behavior Scales. Child–caregiver dyads will be randomized to receive 12 sessions of the PACT intervention (n = 80) or 5 months of community support as usual plus psychoeducation (n = 80). The primary outcome (parent–child interaction) and secondary outcomes (parent-reported social communication abilities and neurophysiological activity during a live social interaction) will be measured pre- and postintervention. This study may lead to new interventions for vulnerable young children in Brazil and better understanding of the neural mechanisms of PACT.

Published
2022

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