1,369 results on '"Mann, Graham"'
Search Results
152. The importance of acid-processed meteoric smoke relative to meteoric fragments for crystal nucleation in polar stratospheric clouds.
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James, Alexander D., Pace, Finn, Sikora, Sebastien N. F., Mann, Graham W., Plane, John M. C., and Murray, Benjamin J.
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OZONE layer ,STRATOSPHERIC chemistry ,VOLCANIC activity prediction ,NUCLEATION ,OZONE layer depletion ,CHEMICAL processes - Abstract
The crystal formation of nitric acid trihydrate (NAT) in the absence of water ice is important for a subset of polar stratospheric clouds (PSCs) and thereby ozone depletion. It has been suggested that either fragmented meteoroids or meteoric smoke particles (MSPs), or possibly both, are important as heterogeneous nuclei of these crystals. Previous work has focused on the nucleating ability of meteoric material in nitric acid in the absence of sulfuric acid. However, it is known that when immersed in stratospheric sulfuric acid droplets, metal-containing meteoric material particles partially dissolve and components can reprecipitate as silica and alumina that have different morphologies to the original meteoric material. Hence, in this study, we experimentally and theoretically explore the relative role that sulfuric acid-processed MSPs and meteoric fragments may play in NAT nucleation in PSCs. We compared meteoric fragments that had recently been prepared (by milling a meteorite sample) to a sample annealed under conditions designed to simulate heating during entry into the Earth's atmosphere. Whilst the addition of sulfuric acid decreased the nucleating ability of the recently milled meteoric material relative to nucleation in binary nitric acid-water solutions (at similar NAT saturation ratio), the annealed meteoric fragments nucleated NAT with a similar effectiveness in both solutions. However, combining our results with measured fluxes of meteoric material to the Earth, sedimentation modelling and recent experiments on fragmentation of incoming meteoroids suggests that it is unlikely for there to be sufficient fragments to contribute to the nucleation of crystalline NAT particles. We then considered silica formed from sulfuric acid-processed MSPs. Our previous work showed that nanoparticulate silica (radius ∼6 nm) is a relatively poor promoter of nucleation compared with micron-scaled silica particles, which were more effective. Both materials have similar chemical and structural (crystallographically amorphous) properties, indicating that size is critical. Here, we account for surface curvature of primary grains using the Classical Nucleation Theory (CNT) to explore this size dependence. This model is able to explain the discrepancy in nucleation effectiveness of fumed silica and fused quartz by treating their nucleating activity (contact angle) as equal but with differing particle size (or surface curvature), assuming interfacial energies that are physically reasonable. Here, we use this CNT model to present evidence that nucleation of NAT on acid-processed MSPs, where the primary grain size is tens of nanometres, is also effective enough to contribute to NAT crystals in early season PSCs where there is an absence of ice. This study demonstrates that the modelling of crystal nucleation in PSCs and resulting ozone depletion relies on an accurate understanding of the transport and chemical processing of MSPs. This will affect estimated sensitivity of stratospheric chemistry to rare events such as large volcanic eruptions and long-term forecasting of ozone recovery in a changing climate. [ABSTRACT FROM AUTHOR]
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- 2023
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153. Genomic and proteomic findings in early melanoma and opportunities for early diagnosis.
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Teh, Rachel, Azimi, Ali, Pupo, Gulietta M., Ali, Marina, Mann, Graham J., and Fernández‐Peñas, Pablo
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MELANOMA ,EARLY diagnosis ,PROTEOMICS ,POST-translational modification ,MELANOMA diagnosis ,PROGNOSIS - Abstract
Overdiagnosis of early melanoma is a significant problem. Due to subtle unique and overlapping clinical and histological criteria between pigmented lesions and the risk of mortality from melanoma, some benign pigmented lesions are diagnosed as melanoma. Although histopathology is the gold standard to diagnose melanoma, there is a demand to find alternatives that are more accurate and cost‐effective. In the current "omics" era, there is gaining interest in biomarkers to help diagnose melanoma early and to further understand the mechanisms driving tumor progression. Genomic investigations have attempted to differentiate malignant melanoma from benign pigmented lesions. However, genetic biomarkers of early melanoma diagnosis have not yet proven their value in the clinical setting. Protein biomarkers may be more promising since they directly influence tissue phenotype, a result of by‐products of genomic mutations, posttranslational modifications and environmental factors. Uncovering relevant protein biomarkers could increase confidence in their use as diagnostic signatures. Currently, proteomic investigations of melanoma progression from pigmented lesions are limited. Studies have previously characterised the melanoma proteome from cultured cell lines and clinical samples such as serum and tissue. This has been useful in understanding how melanoma progresses into metastasis and development of resistance to adjuvant therapies. Currently, most studies focus on metastatic melanoma to find potential drug therapy targets, prognostic factors and markers of resistance. This paper reviews recent advancements in the genomics and proteomic fields and reports potential avenues, which could help identify and differentiate melanoma from benign pigmented lesions and prevent the progression of melanoma. [ABSTRACT FROM AUTHOR]
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- 2023
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154. Validation of self-reported sun exposure against electronic ultraviolet radiation dosimeters.
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Zhang, Ran, Smit, Amelia K, Espinoza, David, Allen, Martin, Reyes-Marcelino, Gillian, Kimlin, Michael G, Lo, Serigne N, Sharman, Ashleigh R, Law, Matthew H, Kanetsky, Peter A, Mann, Graham J, and Cust, Anne E
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SUNSHINE ,DOSIMETERS ,BLAND-Altman plot ,ULTRAVIOLET radiation ,ULTRAVIOLET radiation measurement ,SOLAR ultraviolet radiation - Abstract
From the dosimeter data we derived: (i) time spent outdoors exposed to UV, defined as any 8-s measurements with UV values of >0; and (ii) total standard erythemal doses (SEDs) as a measure of UV dose. Table 1 Spearman rank correlations between weekend and weekday ultraviolet radiation (UV) exposure measured as standard erythemal doses (SEDs) using electronic UV dosimeters HT
. Validation, exposure measurement, ultraviolet radiation, dosimetry, questionnaire, skin cancer Keywords: Validation; exposure measurement; ultraviolet radiation; dosimetry; questionnaire; skin cancer EN Validation exposure measurement ultraviolet radiation dosimetry questionnaire skin cancer 324 328 5 02/16/23 20230201 NES 230201 Ultraviolet radiation (UV) exposure is the main risk factor for skin cancer[1] and skin cancer prevention research and health promotion programme evaluation relies on the accurate measurement of sun exposure using questionnaires. [Extracted from the article] - Published
- 2023
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155. Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma
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Law, Matthew H, Bishop, D Timothy, Lee, Jeffrey E, Brossard, Myriam, Martin, Nicholas G, Moses, Eric K, Song, Fengju, Barrett, Jennifer H, Kumar, Rajiv, Easton, Douglas F, Pharoah, Paul D P, Swerdlow, Anthony J, Kypreou, Katerina P, Taylor, John C, Harland, Mark, Randerson-Moor, Juliette, Akslen, Lars A, Andresen, Per A, Avril, Marie-Françoise, Azizi, Esther, Scarrà, Giovanna Bianchi, Brown, Kevin M, Dȩbniak, Tadeusz, Duffy, David L, Elder, David E, Fang, Shenying, Friedman, Eitan, Galan, Pilar, Ghiorzo, Paola, Gillanders, Elizabeth M, Goldstein, Alisa M, Gruis, Nelleke A, Hansson, Johan, Helsing, Per, Hočevar, Marko, Höiom, Veronica, Ingvar, Christian, Kanetsky, Peter A, Chen, Wei V, Landi, Maria Teresa, Lang, Julie, Lathrop, G Mark, Lubiński, Jan, Mackie, Rona M, Mann, Graham J, Molven, Anders, Montgomery, Grant W, Novaković, Srdjan, Olsson, Håkan, Puig, Susana, Puig-Butille, Joan Anton, Qureshi, Abrar A, Radford-Smith, Graham L, van der Stoep, Nienke, van Doorn, Remco, Whiteman, David C, Craig, Jamie E, Schadendorf, Dirk, Simms, Lisa A, Burdon, Kathryn P, Nyholt, Dale R, Pooley, Karen A, Orr, Nick, Stratigos, Alexander J, Cust, Anne E, Ward, Sarah V, Hayward, Nicholas K, Han, Jiali, Schulze, Hans-Joachim, Dunning, Alison M, Bishop, Julia A Newton, Demenais, Florence, Amos, Christopher I, MacGregor, Stuart, and Iles, Mark M
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- 2015
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156. Development of melanoma clinical quality indicators for the Australian melanoma clinical outcomes registry ( MelCOR ): A modified Delphi study
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Jobson, Dale, primary, Roffey, Benjamin, additional, Arnold, Christopher, additional, Azzi, Anthony, additional, Button‐Sloan, Alison, additional, Dawson, Tamara, additional, Fernandez‐Penas, Pablo, additional, Fishburn, Paul, additional, Gyorki, David E., additional, Hiscutt, Emma L., additional, Jakrot, Valerie, additional, Lilleyman, Alister, additional, Lochhead, Alistair, additional, Long, Georgina V., additional, Mailer, Sonia, additional, Mann, Graham, additional, McCormack, Christopher J., additional, Muir, Jim, additional, Pratt, George F., additional, Scolyer, Richard A., additional, Shackelton, Mark, additional, Shumack, Stephen, additional, Soyer, H. Peter, additional, Tan, Chin‐Guan, additional, Webb, Angela, additional, Zalcberg, John, additional, Morton, Rachael, additional, and Mar, Victoria, additional
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- 2022
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157. Cancer sleep symptom‐related phenotypic clustering differs across three cancer specific patient cohorts
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Kairaitis, Kristina, primary, Madut, Ayey S., additional, Subramanian, Harini, additional, Trivedi, Ritu, additional, Man, Hong, additional, Mather, Marius, additional, Brand, Alison, additional, Elder, Elisabeth, additional, Howle, Julie, additional, Mann, Graham J, additional, Amis, Terence C., additional, and De Fazio, Anna, additional
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- 2022
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158. Ablation Rates of Organic Compounds in Cosmic Dust and Resulting Changes in Mechanical Properties During Atmospheric Entry
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Bones, David L., primary, Carrillo Sánchez, Juan Diego, additional, Connell, Simon D. A., additional, Kulak, Alexander N., additional, Mann, Graham W., additional, and Plane, John M. C., additional
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- 2022
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159. Independent evaluation of melanoma polygenic risk scores in UK and Australian prospective cohorts*
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Steinberg, Julia, primary, Iles, Mark M., additional, Lee, Jin Yee, additional, Wang, Xiaochuan, additional, Law, Matthew H., additional, Smit, Amelia K., additional, Nguyen‐Dumont, Tu, additional, Giles, Graham G., additional, Southey, Melissa C., additional, Milne, Roger L., additional, Mann, Graham J., additional, Bishop, D. Timothy, additional, MacInnis, Robert J., additional, and Cust, Anne E., additional
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- 2022
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160. The Importance of Acid Processed Meteoric Smoke Relative to Meteoric Fragments for Crystal Nucleation in Polar Stratospheric Clouds
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James, Alexander, primary, Pace, Finn, additional, Sikora, Sebastien N. F., additional, Murray, Benjamin J., additional, Mann, Graham W., additional, and Plane, John M. C., additional
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- 2022
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161. Effects of forcing differences and initial conditions on inter-model agreement in the VolMIP volc-pinatubo-full experiment
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Zanchettin, Davide, primary, Timmreck, Claudia, additional, Khodri, Myriam, additional, Schmidt, Anja, additional, Toohey, Matthew, additional, Abe, Manabu, additional, Bekki, Slimane, additional, Cole, Jason, additional, Fang, Shih-Wei, additional, Feng, Wuhu, additional, Hegerl, Gabriele, additional, Johnson, Ben, additional, Lebas, Nicolas, additional, LeGrande, Allegra N., additional, Mann, Graham W., additional, Marshall, Lauren, additional, Rieger, Landon, additional, Robock, Alan, additional, Rubinetti, Sara, additional, Tsigaridis, Kostas, additional, and Weierbach, Helen, additional
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- 2022
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162. Excess mortality in Europe following a future Laki-style Icelandic eruption
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Schmidt, Anja, Ostro, Bart, Carslaw, Kenneth S., Wilson, Marjorie, Thordarson, Thorvaldur, Mann, Graham W., and Simmons, Adrian J.
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- 2011
163. Early-life sun exposure and risk of melanoma before age 40 years
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Cust, Anne E., Jenkins, Mark A., Goumas, Chris, Armstrong, Bruce K., Schmid, Helen, Aitken, Joanne F., Giles, Graham G., Kefford, Richard F., Hopper, John L., and Mann, Graham J.
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- 2011
164. Procedural renunciation and the semi-automatic trap
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Mann, Graham A., Carbonell, Jaime G., editor, Siekmann, Jöorg, editor, Goos, G., editor, Hartmanis, J., editor, van Leeuwen, J., editor, Mugnier, Marie-Laure, editor, and Chein, Michel, editor
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- 1998
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165. Rational and affective linking across conceptual cases — without rules
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Mann, Graham A., Carbonell, J. G., editor, Siekmann, J., editor, Goos, G., editor, Hartmanis, J., editor, van Leeuwen, J., editor, Lukose, Dickson, editor, Delugach, Harry, editor, Keeler, Mary, editor, Searle, Leroy, editor, and Sowa, John, editor
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- 1997
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166. Nonsense Mutations in the Shelterin Complex Genes ACD and TERF2IP in Familial Melanoma
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Aoude, Lauren G., Pritchard, Antonia L., Robles-Espinoza, Carla Daniela, Wadt, Karin, Harland, Mark, Choi, Jiyeon, Gartside, Michael, Quesada, Víctor, Johansson, Peter, Palmer, Jane M., Ramsay, Andrew J., Zhang, Xijun, Jones, Kristine, Symmons, Judith, Holland, Elizabeth A., Schmid, Helen, Bonazzi, Vanessa, Woods, Susan, Dutton-Regester, Ken, Stark, Mitchell S., Snowden, Helen, van Doorn, Remco, Montgomery, Grant W., Martin, Nicholas G., Keane, Thomas M., López-Otín, Carlos, Gerdes, Anne-Marie, Olsson, Håkan, Ingvar, Christian, Borg, Åke, Gruis, Nelleke A., Trent, Jeffrey M., Jönsson, Göran, Bishop, D. Timothy, Mann, Graham J., Newton-Bishop, Julia A., Brown, Kevin M., Adams, David J., and Hayward, Nicholas K.
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- 2015
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167. A single-peak-structured solar cycle signal in stratospheric ozone based on Microwave Limb Sounder observations and model simulations
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Dhomse, Sandip S., primary, Chipperfield, Martyn P., additional, Feng, Wuhu, additional, Hossaini, Ryan, additional, Mann, Graham W., additional, Santee, Michelle L., additional, and Weber, Mark, additional
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- 2022
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168. SurvBenchmark: comprehensive benchmarking study of survival analysis methods using both omics data and clinical data
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Zhang, Yunwei, primary, Wong, Germaine, additional, Mann, Graham, additional, Muller, Samuel, additional, and Yang, Jean Y H, additional
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- 2022
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169. Multiomic profiling of checkpoint inhibitor-treated melanoma: Identifying predictors of response and resistance, and markers of biological discordance
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Newell, Felicity, primary, Pires da Silva, Ines, additional, Johansson, Peter A., additional, Menzies, Alexander M., additional, Wilmott, James S., additional, Addala, Venkateswar, additional, Carlino, Matteo S., additional, Rizos, Helen, additional, Nones, Katia, additional, Edwards, Jarem J., additional, Lakis, Vanessa, additional, Kazakoff, Stephen H., additional, Mukhopadhyay, Pamela, additional, Ferguson, Peter M., additional, Leonard, Conrad, additional, Koufariotis, Lambros T., additional, Wood, Scott, additional, Blank, Christian U., additional, Thompson, John F., additional, Spillane, Andrew J., additional, Saw, Robyn P.M., additional, Shannon, Kerwin F., additional, Pearson, John V., additional, Mann, Graham J., additional, Hayward, Nicholas K., additional, Scolyer, Richard A., additional, Waddell, Nicola, additional, and Long, Georgina V., additional
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- 2022
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170. Recovered measurements of the 1960s stratospheric aerosol layer and UM-UKCA model experiments to assess the Mar 1963 Agung, Sep 1965 Taal and Aug 1966 Awu volcanic aerosol clouds
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Mann, Graham, primary, Antuna-Marrero, Juan-Carlos, additional, Li, Zhengyao, additional, Xu, Jiaying, additional, Dhomse, Sandip, additional, Rosen, James, additional, Rap, Alexandru, additional, Pepin, Ted, additional, Feng, Wuhu, additional, and Deshler, Terry, additional
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- 2021
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171. Association Between Melanoma Detected During Routine Skin Checks and Mortality
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Watts, Caroline G., primary, McLoughlin, Kirstie, additional, Goumas, Chris, additional, van Kemenade, Cathelijne H., additional, Aitken, Joanne F., additional, Soyer, H. Peter, additional, Fernandez Peñas, Pablo, additional, Guitera, Pascale, additional, Scolyer, Richard A., additional, Morton, Rachael L., additional, Menzies, Scott W., additional, Caruana, Michael, additional, Kang, Yoon Jung, additional, Mann, Graham J., additional, Chakera, Annette H., additional, Madronio, Christine M., additional, Armstrong, Bruce K., additional, Thompson, John F., additional, and Cust, Anne E., additional
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- 2021
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172. Supplementary material to "Effects of forcing differences and initial conditions on inter-model agreement in the VolMIP volc-pinatubo-full experiment"
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Zanchettin, Davide, primary, Timmreck, Claudia, additional, Khodri, Myriam, additional, Schmidt, Anja, additional, Toohey, Matthew, additional, Abe, Manabu, additional, Bekki, Slimane, additional, Cole, Jason, additional, Fang, Shih-Wei, additional, Feng, Wuhu, additional, Hegerl, Gabriele, additional, Johnson, Ben, additional, Lebas, Nicolas, additional, LeGrande, Allegra N., additional, Mann, Graham W., additional, Marshall, Lauren, additional, Rieger, Landon, additional, Robock, Alan, additional, Rubinetti, Sara, additional, Tsigaridis, Kostas, additional, and Weierbach, Helen, additional
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- 2021
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173. Effects of forcing differences and initial conditions on inter-model agreement in the VolMIP volc-pinatubo-full experiment
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Zanchettin, Davide, primary, Timmreck, Claudia, additional, Khodri, Myriam, additional, Schmidt, Anja, additional, Toohey, Matthew, additional, Abe, Manabu, additional, Bekki, Slimane, additional, Cole, Jason, additional, Fang, Shih-Wei, additional, Feng, Wuhu, additional, Hegerl, Gabriele, additional, Johnson, Ben, additional, Lebas, Nicolas, additional, LeGrande, Allegra N., additional, Mann, Graham W., additional, Marshall, Lauren, additional, Rieger, Landon, additional, Robock, Alan, additional, Rubinetti, Sara, additional, Tsigaridis, Kostas, additional, and Weierbach, Helen, additional
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- 2021
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174. A rational goal-seeking agent using conceptual graphs
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Mann, Graham A., Goos, G., editor, Hartmanis, J., editor, Carbonell, Jaime G., editor, Siekmann, Jörg, editor, Tepfenhart, William M., editor, Dick, Judith P., editor, and Sowa, John F., editor
- Published
- 1994
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175. Surface antigen profiles of leukocytes and melanoma cells in lymph node metastases are associated with survival in AJCC stage III melanoma patients
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Kaufman, Kimberley L., Mactier, Swetlana, Armstrong, Nicola J., Mallawaaratchy, Duthika, Byrne, Scott N., Haydu, Lauren E., Jakrot, Valerie, Thompson, John F., Mann, Graham J., Scolyer, Richard A., and Christopherson, Richard I.
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- 2014
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176. Assembly of conceptual graphs from natural language by means of multiple knowledge specialists
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Mann, Graham A., Siekmann, Jörg, editor, Goos, G., editor, Hartmanis, J., editor, Pfeiffer, Heather D., editor, and Nagle, Timothy E., editor
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- 1993
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177. Landscape of mutations in early stage primary cutaneous melanoma: An InterMEL study.
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Luo, Li, Shen, Ronglai, Arora, Arshi, Orlow, Irene, Busam, Klaus J., Lezcano, Cecilia, Lee, Tim K., Hernando, Eva, Gorlov, Ivan, Amos, Christopher, Ernstoff, Marc S., Seshan, Venkatraman E., Cust, Anne E., Wilmott, James, Scolyer, Richard A., Mann, Graham, Nagore, Eduardo, Funchain, Pauline, Ko, Jennifer, and Ngo, Peter
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TUMOR-infiltrating immune cells ,MELANOMA ,OLDER patients - Abstract
It is unclear why some melanomas aggressively metastasize while others remain indolent. Available studies employing multi‐omic profiling of melanomas are based on large primary or metastatic tumors. We examine the genomic landscape of early‐stage melanomas diagnosed prior to the modern era of immunological treatments. Untreated cases with Stage II/III cutaneous melanoma were identified from institutions throughout the United States, Australia and Spain. FFPE tumor sections were profiled for mutation, methylation and microRNAs. Preliminary results from mutation profiling and clinical pathologic correlates show the distribution of four driver mutation sub‐types: 31% BRAF; 18% NRAS; 21% NF1; 26% Triple Wild Type. BRAF mutant tumors had younger age at diagnosis, more associated nevi, more tumor infiltrating lymphocytes, and fewer thick tumors although at generally more advanced stage. NF1 mutant tumors were frequent on the head/neck in older patients with severe solar elastosis, thicker tumors but in earlier stages. Triple Wild Type tumors were predominantly male, frequently on the leg, with more perineural invasion. Mutations in TERT, TP53, CDKN2A and ARID2 were observed often, with TP53 mutations occurring particularly frequently in the NF1 sub‐type. The InterMEL study will provide the most extensive multi‐omic profiling of early‐stage melanoma to date. Initial results demonstrate a nuanced understanding of the mutational and clinicopathological landscape of these early‐stage tumors. [ABSTRACT FROM AUTHOR]
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- 2022
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178. Standardized Field Testing of Assistant Robots in a Mars-Like Environment
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Mann, Graham, primary, Small, Nicolas, additional, Lee, Kevin, additional, Clarke, Jonathan, additional, and Sheh, Raymond, additional
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- 2015
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179. Tumour procurement, DNA extraction, coverage analysis and optimisation of mutation-detection algorithms for human melanoma genomes
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Wilmott, James S., Field, Matthew A., Johansson, Peter A., Kakavand, Hojabr, Shang, Ping, De Paoli-Iseppi, Ricardo, Vilain, Ricardo E., Pupo, Gulietta M., Tembe, Varsha, Jakrot, Valerie, Shang, Catherine A., Cebon, Jonathan, Shackleton, Mark, Fitzgerald, Anna, Thompson, John F., Hayward, Nicholas K., Mann, Graham J., and Scolyer, Richard A.
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- 2015
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180. Menʼs preferences and trade-offs for prostate cancer screening: a discrete choice experiment
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Howard, Kirsten, Salkeld, Glenn P., Patel, Manish I., Mann, Graham J., and Pignone, Michael P.
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- 2015
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181. Testing technologies and strategies for exploration in Australian Mars analogues: A review
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West, Michael D., D.A. Clarke, Jonathan, Laing, Jennifer H., Willson, David, Waldie, James M.A., Murphy, Guy M., Thomas, Matilda, and Mann, Graham A.
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- 2010
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182. What Controls the Vertical Distribution of Aerosol? Relationships Between Process Sensitivity in HadGEM3-UKCA and Inter-Model Variation from AeroCom Phase II
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Kipling, Zak, Stier, Philip, Johnson, Colin E, Mann, Graham W, Bellouin, Nicolas, Bauer, Susanne E, Bergman, Tommi, Chin, Mian, Diehl, Thomas, Ghan, Steven J, and Tsigaridis, Kostas
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Meteorology And Climatology - Abstract
The vertical profile of aerosol is important for its radiative effects, but weakly constrained by observations on the global scale, and highly variable among different models. To investigate the controlling factors in one particular model, we investigate the effects of individual processes in HadGEM3-UKCA and compare the resulting diversity of aerosol vertical profiles with the inter-model diversity from the AeroCom Phase II control experiment. In this way we show that (in this model at least) the vertical profile is controlled by a relatively small number of processes, although these vary among aerosol components and particle sizes. We also show that sufficiently coarse variations in these processes can produce a similar diversity to that among different models in terms of the global-mean profile and, to a lesser extent, the zonal-mean vertical position. However, there are features of certain models' profiles that cannot be reproduced, suggesting the influence of further structural differences between models. In HadGEM3-UKCA, convective transport is found to be very important in controlling the vertical profile of all aerosol components by mass. In-cloud scavenging is very important for all except mineral dust. Growth by condensation is important for sulfate and carbonaceous aerosol (along with aqueous oxidation for the former and ageing by soluble material for the latter). The vertical extent of biomass-burning emissions into the free troposphere is also important for the profile of carbonaceous aerosol. Boundary-layer mixing plays a dominant role for sea salt and mineral dust, which are emitted only from the surface. Dry deposition and below-cloud scavenging are important for the profile of mineral dust only. In this model, the microphysical processes of nucleation, condensation and coagulation dominate the vertical profile of the smallest particles by number (e.g. total CN >3 nm), while the profiles of larger particles (e.g. CN>100 nm) are controlled by the same processes as the component mass profiles, plus the size distribution of primary emissions. We also show that the processes that affect the AOD-normalised radiative forcing in the model are predominantly those that affect the vertical mass distribution, in particular convective transport, in-cloud scavenging, aqueous oxidation, ageing and the vertical extent of biomass-burning emissions.
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- 2016
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183. The Effect on Melanoma Risk of Genes Previously Associated With Telomere Length
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Iles, Mark M., Bishop, D. Timothy, Taylor, John C., Hayward, Nicholas K., Brossard, Myriam, Cust, Anne E., Dunning, Alison M., Lee, Jeffrey E., Moses, Eric K., Akslen, Lars A., Andresen, Per A., Avril, Marie-Françoise, Azizi, Esther, Scarrà, Giovanna Bianchi, Brown, Kevin M., Dębniak, Tadeusz, Elder, David E., Friedman, Eitan, Ghiorzo, Paola, Gillanders, Elizabeth M., Goldstein, Alisa M., Gruis, Nelleke A., Hansson, Johan, Harland, Mark, Helsing, Per, Hočevar, Marko, Höiom, Veronica, Ingvar, Christian, Kanetsky, Peter A., Landi, Maria Teresa, Lang, Julie, Lathrop, G. Mark, Lubiński, Jan, Mackie, Rona M., Martin, Nicholas G., Molven, Anders, Montgomery, Grant W., Novaković, Srdjan, Olsson, Håkan, Puig, Susana, Puig-Butille, Joan Anton, Radford-Smith, Graham L., Randerson-Moor, Juliette, van der Stoep, Nienke, van Doorn, Remco, Whiteman, David C., MacGregor, Stuart, Pooley, Karen A., Ward, Sarah V., Mann, Graham J., Amos, Christopher I., Pharoah, Paul D. P., Demenais, Florence, Law, Matthew H., Newton Bishop, Julia A., and Barrett, Jennifer H.
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- 2014
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184. Irregular Sleep/Wake Patterns Are Associated With Reduced Quality of Life in Post-treatment Cancer Patients: A Study Across Three Cancer Cohorts
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Trivedi, Ritu, primary, Man, Hong, additional, Madut, Ayey, additional, Mather, Marius, additional, Elder, Elisabeth, additional, Dhillon, Haryana M., additional, Brand, Alison, additional, Howle, Julie, additional, Mann, Graham, additional, DeFazio, Anna, additional, Amis, Terence, additional, Cain, Sean W., additional, Phillips, Andrew J. K., additional, and Kairaitis, Kristina, additional
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- 2021
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185. Recovery of the first ever multi-year lidar dataset of the stratospheric aerosol layer, from Lexington, MA, and Fairbanks, AK, January 1964 to July 1965
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Antuña-Marrero, Juan-Carlos, primary, Mann, Graham W., additional, Barnes, John, additional, Rodríguez-Vega, Albeht, additional, Shallcross, Sarah, additional, Dhomse, Sandip S., additional, Fiocco, Giorgio, additional, and Grams, Gerald W., additional
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- 2021
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186. 1036Independent evaluation of melanoma polygenic risk scores in UK and Australian prospective cohorts
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Steinberg, Julia, primary, Lee, Jin Yee, additional, Wang, Harry, additional, Law, Matthew, additional, Smit, Amelia, additional, Nguyen-Dumont, Tu, additional, Giles, Graham, additional, Southey, Melissa, additional, Milne, Roger, additional, Mann, Graham, additional, MacInnis, Robert, additional, and Cust, Anne, additional
- Published
- 2021
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187. A Single-Peak-Structured Solar Cycle Signal in Stratospheric Ozone based on Microwave Limb Sounder Observations and Model Simulations
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Dhomse, Sandip S., primary, Chipperfield, Martyn P., additional, Feng, Wuhu, additional, Hossaini, Ryan, additional, Mann, Graham W., additional, Santee, Michelle L., additional, and Weber, Mark, additional
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- 2021
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188. Specialised skin cancer spectral library for use in data‐independent mass spectrometry
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Teh, Rachel, primary, Azimi, Ali, additional, Ali, Marina, additional, Mann, Graham, additional, and Fernández‐Peñas, Pablo, additional
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- 2021
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189. MicroRNA and mRNA expression profiling in metastatic melanoma reveal associations with BRAF mutation and patient prognosis
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Tembe, Varsha, Schramm, Sarah-Jane, Stark, Mitchell S., Patrick, Ellis, Jayaswal, Vivek, Tang, Yue Hang, Barbour, Andrew, Hayward, Nicholas K., Thompson, John F., Scolyer, Richard A., Yang, Yee Hwa, and Mann, Graham J.
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- 2015
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190. Determination of prognosis in metastatic melanoma through integration of clinico-pathologic, mutation, mRNA, microRNA, and protein information
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Jayawardana, Kaushala, Schramm, Sarah-Jane, Haydu, Lauren, Thompson, John F., Scolyer, Richard A., Mann, Graham J., Müller, Samuel, and Yang, Jean Yee Hwa
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- 2015
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191. Specialized Surveillance for Individuals at High Risk for Melanoma: A Cost Analysis of a High-Risk Clinic
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Watts, Caroline G., Cust, Anne E., Menzies, Scott W., Coates, Elliot, Mann, Graham J., and Morton, Rachael L.
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- 2015
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192. CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers
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Johnson, Nichola, Maguire, Sarah, Morra, Anna, Kapoor, Pooja Middha, Tomczyk, Katarzyna, Jones, Michael E., Schoemaker, Minouk J., Gilham, Clare, Bolla, Manjeet K., Wang, Qin, Dennis, Joe, Ahearn, Thomas U., Andrulis, Irene L., Anton-Culver, Hoda, Antonenkova, Natalia N., Arndt, Volker, Aronson, Kristan J., Augustinsson, Annelie, Baynes, Caroline, Freeman, Laura E. Beane, Beckmann, Matthias W., Benitez, Javier, Bermisheva, Marina, Blomqvist, Carl, Boeckx, Bram, Bogdanova, Natalia V., Bojesen, Stig E., Brauch, Hiltrud, Brenner, Hermann, Burwinkel, Barbara, Campa, Daniele, Canzian, Federico, Castelao, Jose E., Chanock, Stephen J., Chenevix-Trench, Georgia, Clarke, Christine L., Conroy, Don M., Couch, Fergus J., Cox, Angela, Cross, Simon S., Czene, Kamila, Dörk, Thilo, Eliassen, A. Heather, Engel, Christoph, Evans, D. Gareth, Fasching, Peter A., Figueroa, Jonine, Floris, Giuseppe, Flyger, Henrik, Gago-Dominguez, Manuela, Gapstur, Susan M., García-Closas, Montserrat, Gaudet, Mia M., Giles, Graham G., Goldberg, Mark S., González-Neira, Anna, Guénel, Pascal, Hahnen, Eric, Haiman, Christopher A., Håkansson, Niclas, Hall, Per, Hamann, Ute, Harrington, Patricia A., Hart, Steven N., Hooning, Maartje J., Hopper, John L., Howell, Anthony, Hunter, David J., Jager, Agnes, Jakubowska, Anna, John, Esther M., Kaaks, Rudolf, Keeman, Renske, Khusnutdinova, Elza, Kitahara, Cari M., Kosma, Veli-Matti, Koutros, Stella, Kraft, Peter, Kristensen, Vessela N., Kurian, Allison W., Lambrechts, Diether, Le Marchand, Loic, Linet, Martha, Lubiński, Jan, Mannermaa, Arto, Manoukian, Siranoush, Margolin, Sara, Martens, John W. M., Mavroudis, Dimitrios, Mayes, Rebecca, Meindl, Alfons, Milne, Roger L., Neuhausen, Susan L., Nevanlinna, Heli, Newman, William G., Nielsen, Sune F., Nordestgaard, Børge G., Obi, Nadia, Olshan, Andrew F., Olson, Janet E., Olsson, Håkan, Orban, Ester, Park-Simon, Tjoung-Won, Peterlongo, Paolo, Plaseska-Karanfilska, Dijana, Pylkäs, Katri, Rennert, Gad, Rennert, Hedy S., Ruddy, Kathryn J., Saloustros, Emmanouil, Sandler, Dale P., Sawyer, Elinor J., Schmutzler, Rita K., Scott, Christopher, Shu, Xiao-Ou, Simard, Jacques, Smichkoska, Snezhana, Sohn, Christof, Southey, Melissa C., Spinelli, John J., Stone, Jennifer, Tamimi, Rulla M., Taylor, Jack A., Tollenaar, Rob A. E. M., Tomlinson, Ian, Troester, Melissa A., Truong, Thérèse, Vachon, Celine M., van Veen, Elke M., Wang, Sophia S., Weinberg, Clarice R., Wendt, Camilla, Wildiers, Hans, Winqvist, Robert, Wolk, Alicja, Zheng, Wei, Ziogas, Argyrios, Dunning, Alison M., Pharoah, Paul D. P., Easton, Douglas F., Howie, A. Forbes, Peto, Julian, dos-Santos-Silva, Isabel, Swerdlow, Anthony J., Chang-Claude, Jenny, Schmidt, Marjanka K., Orr, Nick, Fletcher, Olivia, Børresen-Dale, Anne-Lise, Alnæs, Grethe I. Grenaker, Sahlberg, Kristine K., Ottestad, Lars, Kåresen, Rolf, Schlichting, Ellen, Holmen, Marit Muri, Sauer, Toril, Haakensen, Vilde, Engebråten, Olav, Naume, Bjørn, Fosså, Alexander, Kiserud, Cecile E., Reinertsen, Kristin V., Helland, Åslaug, Riis, Margit, Geisler, Jürgen, Bowtell, David D. L., deFazio, Anna, Webb, Penelope M., Clarke, Christine, Marsh, Deborah, Scott, Rodney, Baxter, Robert, Yip, Desmond, Carpenter, Jane, Davis, Alison, Pathmanathan, Nirmala, Simpson, Peter, Graham, Dinny, Sachchithananthan, Mythily, Amor, David, Andrews, Lesley, Antill, Yoland, Balleine, Rosemary, Beesley, Jonathan, Bennett, Ian, Bogwitz, Michael, Botes, Leon, Brennan, Meagan, Brown, Melissa, Buckley, Michael, Burke, Jo, Butow, Phyllis, Caldon, Liz, Campbell, Ian, Chauhan, Deepa, Chauhan, Manisha, Christian, Alice, Cohen, Paul, Colley, Alison, Crook, Ashley, Cui, James, Cummings, Margaret, Dawson, Sarah-Jane, DeFazio, Anna, Delatycki, Martin, Dickson, Rebecca, Dixon, Joanne, Edkins, Ted, Edwards, Stacey, Farshid, Gelareh, Fellows, Andrew, Fenton, Georgina, Field, Michael, Flanagan, James, Fong, Peter, Forrest, Laura, Fox, Stephen, French, Juliet, Friedlander, Michael, Gaff, Clara, Gattas, Mike, George, Peter, Greening, Sian, Harris, Marion, Hart, Stewart, Hayward, Nick, Hopper, John, Hoskins, Cass, Hunt, Clare, James, Paul, Jenkins, Mark, Kidd, Alexa, Kirk, Judy, Koehler, Jessica, Kollias, James, Lakhani, Sunil, Lawrence, Mitchell, Lindeman, Geoff, Lipton, Lara, Lobb, Liz, Mann, Graham, McLachlan, Sue Anne, Meiser, Bettina, Milne, Roger, Nightingale, Sophie, O’Connell, Shona, O’Sullivan, Sarah, Ortega, David Gallego, Pachter, Nick, Patterson, Briony, Pearn, Amy, Phillips, Kelly, Pieper, Ellen, Rickard, Edwina, Robinson, Bridget, Saleh, Mona, Salisbury, Elizabeth, Saunders, Christobel, Saunus, Jodi, Scott, Clare, Sexton, Adrienne, Shelling, Andrew, Southey, Melissa, Spurdle, Amanda, Taylor, Jessica, Taylor, Renea, Thorne, Heather, Trainer, Alison, Tucker, Kathy, Visvader, Jane, Walker, Logan, Williams, Rachael, Winship, Ingrid, Young, Mary Ann, Johnson, Nichola [0000-0002-8230-5662], Kapoor, Pooja Middha [0000-0001-5503-8215], Dennis, Joe [0000-0003-4591-1214], Brenner, Hermann [0000-0002-6129-1572], Canzian, Federico [0000-0002-4261-4583], Cox, Angela [0000-0002-5138-1099], Fasching, Peter A. [0000-0003-4885-8471], Hart, Steven N. [0000-0001-7714-2734], Jakubowska, Anna [0000-0002-5650-0501], Kurian, Allison W. [0000-0002-6175-9470], Peterlongo, Paolo [0000-0001-6951-6855], Sawyer, Elinor J. [0000-0001-8285-4111], Tomlinson, Ian [0000-0003-3037-1470], Truong, Thérèse [0000-0002-2943-6786], Pharoah, Paul D. P. [0000-0001-8494-732X], Peto, Julian [0000-0002-1685-8912], Apollo - University of Cambridge Repository, Medical Oncology, HUS Comprehensive Cancer Center, Department of Oncology, Clinicum, Helsinki University Hospital Area, University of Helsinki, HUS Gynecology and Obstetrics, Department of Obstetrics and Gynecology, Fasching, Peter A [0000-0003-4885-8471], Hart, Steven N [0000-0001-7714-2734], Kurian, Allison W [0000-0002-6175-9470], Sawyer, Elinor J [0000-0001-8285-4111], and Pharoah, Paul DP [0000-0001-8494-732X]
- Subjects
Cancer Research ,CYP3A5 ,Physiology ,Genome-wide association study ,Breast cancer ,0302 clinical medicine ,Epidemiology ,Receptors ,IMPUTATION ,Medicine ,Cytochrome P-450 CYP3A ,Cancer genetics ,Progesterone ,0303 health sciences ,article ,1112 Oncology and Carcinogenesis, 1117 Public Health and Health Services ,AOCS Group ,Single Nucleotide ,humanities ,3. Good health ,Receptors, Estrogen ,Oncology ,Hormone receptor ,030220 oncology & carcinogenesis ,kConFab Investigators ,Pregnanediol ,Female ,Receptors, Progesterone ,Medical Genetics ,medicine.medical_specialty ,Estrone ,Urinary system ,3122 Cancers ,ABCTB Investigators ,631/67/2324 ,Breast Neoplasms ,Polymorphism, Single Nucleotide ,NBCS Collaborators ,03 medical and health sciences ,Cancer epidemiology ,SDG 3 - Good Health and Well-being ,631/67/68 ,Humans ,Oncology & Carcinogenesis ,Allele ,GENOME-WIDE ASSOCIATION ,Polymorphism ,CYP3A7 ,Alleles ,030304 developmental biology ,Medicinsk genetik ,business.industry ,631/67/1347 ,medicine.disease ,Case-Control Studies ,Genome-Wide Association Study ,Premenopause ,Estrogen ,business ,Hormone - Abstract
Background Epidemiological studies provide strong evidence for a role of endogenous sex hormones in the aetiology of breast cancer. The aim of this analysis was to identify genetic variants that are associated with urinary sex-hormone levels and breast cancer risk. Methods We carried out a genome-wide association study of urinary oestrone-3-glucuronide and pregnanediol-3-glucuronide levels in 560 premenopausal women, with additional analysis of progesterone levels in 298 premenopausal women. To test for the association with breast cancer risk, we carried out follow-up genotyping in 90,916 cases and 89,893 controls from the Breast Cancer Association Consortium. All women were of European ancestry. Results For pregnanediol-3-glucuronide, there were no genome-wide significant associations; for oestrone-3-glucuronide, we identified a single peak mapping to the CYP3A locus, annotated by rs45446698. The minor rs45446698-C allele was associated with lower oestrone-3-glucuronide (−49.2%, 95% CI −56.1% to −41.1%, P = 3.1 × 10–18); in follow-up analyses, rs45446698-C was also associated with lower progesterone (−26.7%, 95% CI −39.4% to −11.6%, P = 0.001) and reduced risk of oestrogen and progesterone receptor-positive breast cancer (OR = 0.86, 95% CI 0.82–0.91, P = 6.9 × 10–8). Conclusions The CYP3A7*1C allele is associated with reduced risk of hormone receptor-positive breast cancer possibly mediated via an effect on the metabolism of endogenous sex hormones in premenopausal women.
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- 2021
193. The recovery and re-calibration of a 13-month aerosol extinction profiles dataset from searchlight observations from New Mexico, after the 1963 Agung eruption.
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Antuña-Marrero, Juan-Carlos, Mann, Graham W., Barnes, John, Calle, Abel, Dhomse, Sandip S., Revilla, Victoria E. Cachorro, Deshler, Terry, Li Zhengyao, Sharma, Nimmi, and Elterman, Louis
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TROPOSPHERIC aerosols , *STRATOSPHERIC aerosols , *AEROSOLS , *DATA libraries , *PARTICLE size distribution , *VOLCANIC eruptions ,PANGAEA (Supercontinent) - Abstract
We report the recovery and re-calibration of an extensive dataset of vertical profile measurements of the 1963/64 stratospheric aerosol layer measured from a two-site searchlight measurement facility at White Sands missile base and Sacramento Peak observatory, in New Mexico, US. The recovered dataset comprises 105 profiles of 550nm aerosol extinction (βp(z)) and is part of a longer program of measurements with the US Air Force Cambridge Research Laboratories (AFCRL) searchlight facility that began in February 1963. The recovered series of βp(z) profiles span the 13-month period December 1963 to December 1964 and provide a unique record of the altitude and vertical extent of the Northern Hemisphere dispersed portion of the aerosol cloud from the March 1963 Agung volcanic eruption. The data recovery methodology involved first re-digitizing the 105 original βp(z) profiles (βp(z)) from individual Figures within an AFCRL research report (Elterman, 1966a). The re-calibration involves inverting the original equation used to compute βp(z) in Elterman (1966a; 1966b) to retrieve a normalized detector response (Er(z) Er(35)) profile for each of the 105 re-digitized βp 0(z) profiles. An iterative procedure was then used to compute the re-calibration βp(z) profiles (βp Ra(z)), with the molecular extinction profile calculated with the corresponding daily molecular extinction profile calculated from local soundings, rather than the US Standard Atmosphere 1962 in the original dataset. Two-way molecular and aerosol transmittance corrections are applied using the MODTRAN (MODerate resolution atmospheric TRANsmission) code in transmission mode, applying a best-estimate aerosol phase function calculated from measurements, applied for the entire 2.76 to 35.2 km column. For the tropospheric aerosol transmittance, the AERONET aerosol phase function from White Sands High Energy Laser Systems Test Facility (HELSTF) was applied (2.76 to 10.7 km), a separate stratospheric phase function applied between 11.2 and 35.2 km, calculated from a set of particle size distributions measured by the U-2 high-altitude aircraft over a US region in the vicinity of White Sands in early 1964. Errors were estimated taking as a reference the errors determined in the computation of βp 0(z). Using available tabulated data from the original procedure the errors in the re-digitalization of βp 0(z) and in the retrieval of the Er(z) Er(35) procedures were calculated and later added to the original estimates. Both the βp R(z) and the stratospheric aerosol optical depth magnitudes showed higher magnitudes than βp 0(z) and the original stratospheric aerosol optical depth, however their magnitudes show a reasonable agreement with other contemporary observations. Both the original and recalibration datasets are being submitted to PANGAEA data repository for its storage and public access. [ABSTRACT FROM AUTHOR]
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- 2022
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194. The importance of acid processed meteoric smoke relative to meteoric fragments for crystal nucleation in polar stratospheric clouds.
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James, Alexander D., Pace, Finn, Sikora, Sebastien N. F., Mann, Graham W., Plane, John M. C., and Murray, Benjamin J.
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Nitric Acid Trihydrate (NAT) crystal formation in the absence of water ice is important for a subset of Polar Stratospheric Clouds (PSCs) and thereby ozone depletion. It has been suggested that either fragmented meteoroids or meteoric smoke particles (MSPs), or possibly both, are important as heterogeneous nuclei of these crystals. Previous work has focused on the nucleating ability of meteoric material in nitric acid in the absence of sulfuric acid. However, it is known that when immersed in stratospheric sulfuric acid droplets, metal-containing meteoric material particles partially dissolve and components can re-precipitate as silica and alumina that have different morphologies to the original meteoric material. Hence, in this study we experimentally and theoretically explore the relative role that sulfuric acid-processed meteoric smoke and meteoric fragments may play in NAT nucleation in PSCs. We compared meteoric fragments that had been recently prepared (by milling a meteorite sample) to a sample annealed under conditions designed to simulate heating during entry into the Earth's atmosphere. Whilst the addition of sulfuric acid decreased the nucleating ability of the recently milled meteoric material relative to nucleation in binary nitric acid-water solutions (at similar NAT saturation ratio), the annealed meteoric fragments nucleated NAT with a similar effectiveness in both solutions. However, combining our results with measured fluxes of meteoric material to the Earth, sedimentation modelling and recent experiments on fragmentation of incoming meteoroids, suggests that there are unlikely to be sufficient fragments to contribute to the nucleation of crystalline NAT particles. We then considered silica formed from sulfuric acid processed meteoric smoke particles. Our previous work showed that nanoparticulate silica (radius ~6 nm) is a relatively poor promoter of nucleation compared with micron scaled silica particles, which were more effective. Both materials have similar chemical and structural (crystallographically amorphous) properties, indicating size is critical. Here we account for surface curvature of primary grains using Classical Nucleation Theory (CNT) to explore this size dependence. This model is able to explain the discrepancy in nucleation effectiveness of fumed silica and fused quartz, by treating their nucleating activity (contact angle) as equal but with differing particle size (or surface curvature), assuming interfacial energies that are physically reasonable. Here we use this CNT model to present evidence that nucleation of NAT on acid processed MSPs, where the primary grain size is 10s nm, is also effective enough to contribute to NAT crystals in early season PSCs where there is an absence of ice. This study demonstrates that modelling of crystal nucleation in PSCs and resulting ozone depletion relies on accurate understanding of the transport and chemical processing of MSPs. This will affect estimated sensitivity of stratospheric chemistry to rare events such as large volcanic eruptions and long-term forecasting of ozone recovery in a changing climate. [ABSTRACT FROM AUTHOR]
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- 2022
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195. Interactive Stratospheric Aerosol models response to different amount and altitude of SO2 injections during the 1991 Pinatubo eruption.
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Quaglia, Ilaria, Timmreck, Claudia, Niemeier, Ulrike, Visioni, Daniele, Pitari, Giovanni, Brühl, Christoph, Dhomse, Sandip, Franke, Henning, Laakso, Anton, Mann, Graham, Rozanov, Eugene, and Sukhodolov, Timofei
- Abstract
Recent model inter-comparison studies highlighted model discrepancies in reproducing the climatic impacts of large explosive volcanic eruptions, calling into question the reliability of global aerosol model simulations for future scenarios. Here, we analyse the simulated evolution of the stratospheric aerosol plume following the well observed June 1991 Mt. Pinatubo eruption by six interactive stratospheric aerosol microphysics models in comparison to a range of observational data sets. Our primary focus 5 is on the uncertainties regarding initial SO
2 emission following the Pinatubo eruption in 1991, as prescribed in the Historical Eruptions SO2 Emission Assessment experiments (HErSEA), in the framework of the Interactive Stratospheric Aerosol Model Intercomparison Project (ISA-MIP). Six global models with interactive aerosol microphysics took part in this study: ECHAM6-SALSA, EMAC, ECHAM5-HAM, SOCOL-AERv2, ULAQ-CCM and UM-UKCA. Model simulations are performed by varying SO2 injection amount (ranging between 5 and 10 Tg-S), and the altitude of injection (between 18-25 km). We find that the common and main weakness among all the models is that they can not reproduce the persistence of the sulfate aerosols in the stratosphere. Most models show a stronger transport towards the extratropics in the northern hemisphere, at the expense of the observed tropical confinement, suggesting a much weaker subtropical barrier in all the models, that results in a shorter e-folding time compared to the observations. Moreover, the simulations in which more than 5 Tg-S of SO2 are injected show a large surface area density a few months after the eruption compared to the values measured in the tropics and the in-situ measurements over Laramie. This results in an overestimation of the number of particles globally during the build-up phase and an underestimation in the Southern Hemisphere, which draws attention to the importance of including processes as the ash injection and the eruption of Cerro Hudson. [ABSTRACT FROM AUTHOR]- Published
- 2022
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196. Protein signatures correspond to survival outcomes of AJCC stage III melanoma patients
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Mactier, Swetlana, Kaufman, Kimberley L., Wang, Penghao, Crossett, Ben, Pupo, Gulietta M., Kohnke, Philippa L., Thompson, John F., Scolyer, Richard A., Yang, Jean Y., Mann, Graham J., and Christopherson, Richard I.
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- 2014
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197. About the Cancer Research Network
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Mann, Graham
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- 2014
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198. SurvBenchmark: comprehensive benchmarking study of survival analysis methods using both omics data and clinical data
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Zhang, Yunwei, primary, Wong, Germaine, additional, Mann, Graham, additional, Muller, Samuel, additional, and Yang, Jean Y.H., additional
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- 2021
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199. Unknown Eruption Source Parameters Cause Large Uncertainty in Historical Volcanic Radiative Forcing Reconstructions
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Marshall, Lauren R., primary, Schmidt, Anja, additional, Johnson, Jill S., additional, Mann, Graham W., additional, Lee, Lindsay A., additional, Rigby, Richard, additional, and Carslaw, Ken S., additional
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- 2021
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200. Identifying the ‘Active Ingredients' of an Effective Psychological Intervention to Reduce Fear of Cancer Recurrence: A Process Evaluation
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Kan, Janice M., primary, Dieng, Mbathio, additional, Butow, Phyllis N., additional, Mireskandari, Shab, additional, Tesson, Stephanie, additional, Menzies, Scott W., additional, Costa, Daniel S. J., additional, Morton, Rachael L., additional, Mann, Graham J., additional, Cust, Anne E., additional, and Kasparian, Nadine A., additional
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- 2021
- Full Text
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