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199 results on '"M. Kilbinger"'

151. Non-aggregating Poly(p-benzamide)s

Author

Maren Schulze, Christof Storz, and Andreas F. M. Kilbinger

Subjects
chemistry.chemical_compound, Materials science, chemistry, Stereochemistry, 02 engineering and technology, General Medicine, General Chemistry, 010402 general chemistry, 021001 nanoscience & nanotechnology, 0210 nano-technology, Benzamide, 01 natural sciences, 0104 chemical sciences
Published
2012
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152. H-bonding schemes of di- and tri-p-benzamides assessed by a combination of electron diffraction, X-ray powder diffraction and solid-state NMR

Author

Anne Bohle, Galina Matveeva, Ute Kolb, Andreas F. M. Kilbinger, Tobias W. Schleuss, J. van de Streek, Gunther Brunklaus, and Tatiana Gorelik

Subjects
Diffraction, Crystallography, Electron diffraction, Chemistry, General Materials Science, General Chemistry, Nuclear magnetic resonance crystallography, Crystal structure, Selected area diffraction, Condensed Matter Physics, Single crystal, Powder diffraction, Electron backscatter diffraction
Abstract

The crystal structures of di- and tri-p-benzamides are solved by a combination of single crystal, electron and powder X-ray diffraction. Different hydrogen-bonding schemes observed in the two structures are described and classified. The hydrogen-bonding networks are correlated to complementary data obtained from multinuclear solid-state NMR.

Published
2010
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154. Mass spectrometric evidence for aggregation of a substituted sexithiophene

Author

E. W. Meijer, Peter J. Derrick, Helen J. Cooper, Liam A. McDonnell, W. J. Feast, Andreas F. M. Kilbinger, Albertus P. H. J. Schenning, Macromolecular and Organic Chemistry, and Macro-Organic Chemistry

Subjects
Chromatography, Computational chemistry, Chemistry, Materials Chemistry, Metals and Alloys, Ceramics and Composites, General Chemistry, Mass spectrometry, Mass spectrometric, Catalysis, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials
Abstract

Nanospray FT-ICR mass spectroscopy provides unambiguous evidence for solvent-dependent aggregation of a substituted sexithiophene.

Published
2000

156. Macromol. Rapid Commun. 6/2007

Author

Francisco-Javier López-Villanueva, Holger Frey, Andreas F. M. Kilbinger, and Frederik R. Wurm

Subjects
Polymers and Plastics, Organic Chemistry, Materials Chemistry
Published
2007
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157. Synthesis of Monofunctional Metathesis Polymers

Author

Andreas F. M. Kilbinger, Robert H. Grubbs, E. Berger-Nicoletti, and S. Hilf

Subjects
chemistry.chemical_classification, chemistry, Copolymer, Organic chemistry, Ring-opening metathesis polymerisation, Chain transfer, Polymer, Metathesis, Acyclic diene metathesis
Published
2007
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158. Solid-Phase Synthesis of Oligo(p-benzamide) Foldamers

Author

Hannah M. König, Robert Abbel, Dieter Schollmeyer, and Andreas F. M. Kilbinger

Subjects
chemistry.chemical_compound, Monomer, Thionyl chloride, Solid-phase synthesis, chemistry, Organic Chemistry, Supramolecular chemistry, Organic chemistry, Physical and Theoretical Chemistry, Benzamide, Biochemistry, Combinatorial chemistry
Abstract

[reaction: see text] A coupling protocol has been developed which allows the synthesis of oligo(p-benzamide)s on solid support. Aromatic carboxylic acids are activated in situ with thionyl chloride and used to acylate secondary aromatic amines. N-p-Methoxy benzyl (PMB) as well as N-hexyl protected monomers were investigated. Heterosequences of both monomers were synthesized. Such nanoscale objects are important building blocks for supramolecular chemistry.

Published
2006
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160. H-bonding schemes of di- and tri-p-benzamides assessed by a combination of electron diffraction, X-ray powder diffraction and solid-state NMRCCDC reference numbers 750010and 750011. For crystallographic data in CIF or other electronic format see DOI: 10.1039/b920569a

Author

Tatiana Gorelik, Galina Matveeva, Ute Kolb, Tobias Schleuß, Andreas F. M. Kilbinger, Jacco van de Streek, Anne Bohle, and Gunther Brunklaus

Subjects
HYDROGEN bonding, BENZAMIDE, ELECTRON diffraction, SOLID state chemistry, NUCLEAR magnetic resonance spectroscopy, X-ray crystallography
Abstract

The crystal structures of di- and tri-p-benzamides are solved by a combination of single crystal, electron and powder X-ray diffraction. Different hydrogen-bonding schemes observed in the two structures are described and classified. The hydrogen-bonding networks are correlated to complementary data obtained from multinuclear solid-state NMR. [ABSTRACT FROM AUTHOR]

Published
2010
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167. Rod–coil copolymers from oligo(p-benzamide) foldamersElectronic supplementary information (ESI) available: Experimental; X-ray structure of 8; HPLC elugrams; mass and NMR spectra. See DOI: 10.1039/b617598h.

Author

Helga Seyler, Elena Berger-Nicoletti, and Andreas F. M. Kilbinger

Abstract

Self assembling rod–coil copolymers were synthesized in which oligo(p-benzamide) rods up to the octamer were prepared via iterative solution synthesis employing the acid labile 2,4-dimethoxybenzyl amide protective group. [ABSTRACT FROM AUTHOR]

Published
2007
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169. Supramolecular Electronic Coupling in Chiral Oligothiophene NanostructuresThe work in Cambridge was supported by the UK Engineering and Physical Sciences Research Council (EPSRC) via an Advanced Research Fellowship for C. S. A. A. thanks the University of Bari and Prof. Raffaele Tommasi for partial funding to carry out this research in Cambridge. The work in Durham was supported by the EPSRC. The Cambridge–Eindhoven–Durham collaboration was supported by the European Commission (LAMINATE). C. S. acknowledges support from the Canadian National Science and Engineering Research Council (NSERC) and from the Canada Research Chairs Programme. Supporting Information is available online from Wiley InterScience or from the author.

Author

S. Westenhoff, A. Abrusci, W. J. Feast, O. Henze, A. F. M. Kilbinger, A. P. H. J. Schenning, and C. Silva

Published
2006
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171. Surface-controlled self-assembly of chiral sexithiophenes.

Author

Philippe Leclère, Mathieu Surin, Roberto Lazzaroni, Andreas F. M. Kilbinger, Oliver Henze, Pascal Jonkheijm, Fabio Biscarini, Massimiliano Cavallini, W. James Feast, E. W. Meijer, and Albertus P. H. J. Schenning

Published
2004

172. Solid-Phase Synthesis of Oligo(p-benzamide) Foldamers

Author

M. König, Hannah, Abbel, Robert, Schollmeyer, Dieter, and F. M. Kilbinger, Andreas

Abstract

A coupling protocol has been developed which allows the synthesis of oligo(p-benzamide)s on solid support. Aromatic carboxylic acids are activated in situ with thionyl chloride and used to acylate secondary aromatic amines. N-p-Methoxy benzyl (PMB) as well as N-hexyl protected monomers were investigated. Heterosequences of both monomers were synthesized. Such nanoscale objects are important building blocks for supramolecular chemistry.

Published
2006
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173. The influence of substituents on gelation and stacking order of oligoaramid – based supramolecular networks

Author

Sandor Balog, Susanne Drechsler, Andreas F. M. Kilbinger, and Tommaso Casalini

Subjects
Materials science, Small-angle X-ray scattering, Stacking, Supramolecular chemistry, technology, industry, and agriculture, 02 engineering and technology, General Chemistry, 010402 general chemistry, 021001 nanoscience & nanotechnology, Condensed Matter Physics, Smart material, 01 natural sciences, Oligomer, 0104 chemical sciences, chemistry.chemical_compound, Molecular dynamics, chemistry, Chemical physics, Self-healing hydrogels, 0210 nano-technology, Spectroscopy
Abstract

Self-assembly has proven to be a powerful tool for functional, smart materials such as hydrogels derived from low molecular weight compounds. However, the targeted design of functional gelators remains difficult. Here, we present a set of four Y-shaped aromatic amide tetramers with varying functionalities able to undergo different non- covalent interactions. These compounds were explored towards their self-assembly behavior and hydrogel formation by experimental methods such as UV-vis spectroscopy, rheology, small angle X-ray scattering (SAXS), scanning/transmission electron, and atomic force microscopy. Additionally, we investigated the main mechanisms behind oligomer aggregation and the structure of the resulting supramolecular chains through full atomistic molecular dynamics simulations.

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174. ShapePipe: A modular weak-lensing processing and analysis pipeline

Author

S. Farrens, A. Guinot, M. Kilbinger, T. Liaudat, L. Baumont, X. Jimenez, A. Peel, A. Pujol, M. Schmitz, J.-L. Starck, A. Z. Vitorelli, Astrophysique Interprétation Modélisation (AIM (UMR7158 / UMR_E_9005 / UM_112)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université Paris-Saclay, Joseph Louis LAGRANGE (LAGRANGE), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, and COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)

Subjects
catalog, Cosmology and Nongalactic Astrophysics (astro-ph.CO), a-type stars, gravitational lensing, data analysis, halo, FOS: Physical sciences, weak, Astronomy and Astrophysics, france imaging survey, methods: data analysis, methods, python, gravitational lensing: weak, Space and Planetary Science, mass, mpi, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], Astrophysics - Instrumentation and Methods for Astrophysics, Instrumentation and Methods for Astrophysics (astro-ph.IM), sextractor, milky-way, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We present the first public release of ShapePipe, an open-source and modular weak-lensing measurement, analysis, and validation pipeline written in Python. We describe the design of the software and justify the choices made. We provide a brief description of all the modules currently available and summarise how the pipeline has been applied to real Ultraviolet Near-Infrared Optical Northern Survey data. Finally, we mention plans for future applications and development. The code and accompanying documentation are publicly available on GitHub., 7 pages, 2 figures, accepted for publication in A&A

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175. Euclid preparation

Author

A. Balaguera-Antolinez, M. Frailis, C. Colodro-Conde, Ralf Bender, Pedro G. Ferreira, Andrea Biviano, V. Capobianco, L. Patrizii, Jason Rhodes, Jean Coupon, L. Conversi, Luca Valenziano, B. Gillis, G. Congedo, S. Dusini, Frank Grupp, M. Tenti, E. Romelli, S. Bardelli, Davide Maino, Felix Hormuth, Hélène M. Courtois, F. J. Castander, Chiara Sirignano, E. Zucca, Martin Kunz, D. Bonino, Y. Copin, M. Poncet, E. Munari, D. Masters, D. Tavagnacco, Henk Hoekstra, Simona Mei, Marco Baldi, Natalia Auricchio, Stefano Camera, A. Pocino, Leonardo Corcione, C. J. Conselice, B. Garilli, M. H. Fabricius, F. Dubath, Helmut Hildebrandt, Yu Wang, Marco Castellano, M. Kilbinger, S. Kermiche, F. Torradeflot, Ariel G. Sánchez, V. Scottez, Stefano Cavuoti, Massimo Meneghetti, Mauro Roncarelli, Domenico Sapone, Valentina Guglielmo, O. Ilbert, I. Lloro, Gianluca Castignani, Claudia Maraston, Andrea Zacchei, S. Farrens, S. Maurogordato, Richard Massey, Knud Jahnke, Sotiria Fotopoulou, Stefano Andreon, C. C. Kirkpatrick, H. Israel, Peter Capak, S. Brau-Nogue, G. Sirri, P. B. Lilje, Peter Schneider, Andrea Tramacere, Giuseppe Riccio, Andrea Cimatti, E. Keihänen, Massimo Brescia, D. Di Ferdinando, A. Renzi, A. Da Silva, C. Bodendorf, Ole Marggraf, C. A. J. Duncan, Elisabetta Maiorano, Rafael Toledo-Moreo, S. de la Torre, B. Kubik, Enrico Bozzo, S. Casas, S. Niemi, J. Carretero, C. S. Carvalho, Carlo Giocoli, Lucia Pozzetti, L. Whittaker, Fabio Pasian, Anne Costille, M. Bolzonella, Enzo Branchini, A. Secroun, Ghassem Gozaliasl, R. Cledassou, N. Martinet, Mark Cropper, Carlo Burigana, Ismael Tereno, G. Meylan, A. Cappi, X. Dupac, Lauro Moscardini, Roberto P. Saglia, Carmelita Carbone, P. Tallada-Crespí, A. A. Nucita, R. Nakajima, René J. Laureijs, D. Stern, Luigi Guzzo, S. Paltani, Michele Moresco, F. Raison, C. Neissner, S. Serrano, G. Zamorani, Ricard Casas, Emanuel Rossetti, C. Padilla, Julien Zoubian, T. Vassallo, R. Benton Metcalf, E. Medinaceli, E. Franceschi, Javier Graciá-Carpio, Remi A. Cabanac, S. Galeotta, Audrey Galametz, Andy Taylor, F. Sureau, Sebastiano Ligori, Hannu Kurki-Suonio, M. Wetzstein, N. Welikala, Thomas D. Kitching, Federico Marulli, M. Fumana, Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Institut de recherche en astrophysique et planétologie (IRAP), Institut national des sciences de l'Univers (INSU - CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Observatoire Midi-Pyrénées (OMP), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS), Joseph Louis LAGRANGE (LAGRANGE), Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Astrophysique Interprétation Modélisation (AIM (UMR_7158 / UMR_E_9005 / UM_112)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Centre National d'Études Spatiales [Toulouse] (CNES), Institut de Physique des 2 Infinis de Lyon (IP2I Lyon), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Etude du Rayonnement et de la Matière en Astrophysique (LERMA (UMR_8112)), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-CY Cergy Paris Université (CY), Institut d'Astrophysique de Paris (IAP), Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Guglielmo, V., Saglia, R., Castander, F. J., Galametz, A., Paltani, S., Bender, R., Bolzonella, M., Capak, P., Ilbert, O., Masters, D. C., Stern, D., Andreon, S., Auricchio, N., Balaguera-Antolinez, A., Baldi, M., Bardelli, S., Biviano, A., Bodendorf, C., Bonino, D., Bozzo, E., Branchini, E., Brau-Nogue, S., Brescia, M., Burigana, C., Cabanac, R. A., Camera, S., Capobianco, V., Cappi, A., Carbone, C., Carretero, J., Carvalho, C. S., Casas, R., Casas, S., Castellano, M., Castignani, G., Cavuoti, S., Cimatti, A., Cledassou, R., Colodro-Conde, C., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Costille, A., Coupon, J., Courtois, H. M., Cropper, M., Da Silva, A., De La Torre, S., Di Ferdinando, D., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Fabricius, M., Farrens, S., Ferreira, P. G., Fotopoulou, S., Frailis, M., Franceschi, E., Fumana, M., Galeotta, S., Garilli, B., Gillis, B., Giocoli, C., Gozaliasl, G., Gracia-Carpio, J., Grupp, F., Guzzo, L., Hildebrandt, H., Hoekstra, H., Hormuth, F., Israel, H., Jahnke, K., Keihanen, E., Kermiche, S., Kilbinger, M., Kirkpatrick, C. C., Kitching, T., Kubik, B., Kunz, M., Kurki-Suonio, H., Laureijs, R., Ligori, S., Lilje, P. B., Lloro, I., Maino, D., Maiorano, E., Maraston, C., Marggraf, O., Martinet, N., Marulli, F., Massey, R., Maurogordato, S., Medinaceli, E., Mei, S., Meneghetti, M., Benton Metcalf, R., Meylan, G., Moresco, M., Moscardini, L., Munari, E., Nakajima, R., Neissner, C., Niemi, S., Nucita, A. A., Padilla, C., Pasian, F., Patrizii, L., Pocino, A., Poncet, M., Pozzetti, L., Raison, F., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Roncarelli, M., Rossetti, E., Sanchez, A. G., Sapone, D., Schneider, P., Scottez, V., Secroun, A., Serrano, S., Sirignano, C., Sirri, G., Sureau, F., Tallada-Crespi, P., Tavagnacco, D., Taylor, A. N., Tenti, M., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Tramacere, A., Valenziano, L., Vassallo, T., Wang, Y., Welikala, N., Wetzstein, M., Whittaker, L., Zacchei, A., Zamorani, G., Zoubian, J., Zucca, E., Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Etude du Rayonnement et de la Matière en Astrophysique et Atmosphères = Laboratory for Studies of Radiation and Matter in Astrophysics and Atmospheres (LERMA), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-CY Cergy Paris Université (CY), Guglielmo V., Saglia R., Castander F.J., Galametz A., Paltani S., Bender R., Bolzonella M., Capak P., Ilbert O., Masters D.C., Stern D., Andreon S., Auricchio N., Balaguera-Antolinez A., Baldi M., Bardelli S., Biviano A., Bodendorf C., Bonino D., Bozzo E., Branchini E., Brau-Nogue S., Brescia M., Burigana C., Cabanac R.A., Camera S., Capobianco V., Cappi A., Carbone C., Carretero J., Carvalho C.S., Casas R., Casas S., Castellano M., Castignani G., Cavuoti S., Cimatti A., Cledassou R., Colodro-Conde C., Congedo G., Conselice C.J., Conversi L., Copin Y., Corcione L., Costille A., Coupon J., Courtois H.M., Cropper M., Da Silva A., De La Torre S., Di Ferdinando D., Dubath F., Duncan C.A.J., Dupac X., Dusini S., Fabricius M., Farrens S., Ferreira P.G., Fotopoulou S., Frailis M., Franceschi E., Fumana M., Galeotta S., Garilli B., Gillis B., Giocoli C., Gozaliasl G., Gracia-Carpio J., Grupp F., Guzzo L., Hildebrandt H., Hoekstra H., Hormuth F., Israel H., Jahnke K., Keihanen E., Kermiche S., Kilbinger M., Kirkpatrick C.C., Kitching T., Kubik B., Kunz M., Kurki-Suonio H., Laureijs R., Ligori S., Lilje P.B., Lloro I., Maino D., Maiorano E., Maraston C., Marggraf O., Martinet N., Marulli F., Massey R., Maurogordato S., Medinaceli E., Mei S., Meneghetti M., Benton Metcalf R., Meylan G., Moresco M., Moscardini L., Munari E., Nakajima R., Neissner C., Niemi S., Nucita A.A., Padilla C., Pasian F., Patrizii L., Pocino A., Poncet M., Pozzetti L., Raison F., Renzi A., Rhodes J., Riccio G., Romelli E., Roncarelli M., Rossetti E., Sanchez A.G., Sapone D., Schneider P., Scottez V., Secroun A., Serrano S., Sirignano C., Sirri G., Sureau F., Tallada-Crespi P., Tavagnacco D., Taylor A.N., Tenti M., Tereno I., Toledo-Moreo R., Torradeflot F., Tramacere A., Valenziano L., Vassallo T., Wang Y., Welikala N., Wetzstein M., Whittaker L., Zacchei A., Zamorani G., Zoubian J., Zucca E., Academy of Finland, European Commission, Agenzia Spaziale Italiana, Belgian Science Policy Office, Canadian Euclid Consortium, Centre National D'Etudes Spatiales (France), Danish Space Research Institute, German Centre for Air and Space Travel, Fundação para a Ciência e a Tecnologia (Portugal), Ministerio de Economía y Competitividad (España), National Aeronautics and Space Administration (US), Netherlands Research School for Astronomy, Norwegian Space Agency, Romanian Space Agency, State Secretariat for Education, Research and Innovation (Switzerland), Swiss Space Office, UK Space Agency, Ministerio de Ciencia, Innovación y Universidades (España), Collaboration, Euclid, Department of Physics, and Helsinki Institute of Physics

Subjects
German aerospace, [SDU.ASTR.CO]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO], Astrophysics, Surveys, Cosmology: observation, 01 natural sciences, 7. Clean energy, MAPS, Agency (sociology), galaxies, Galaxies: distances and redshift, Astrophysics::Solar and Stellar Astrophysics, distances and redshifts, Space research, observations [Cosmology], PHOTOMETRIC REDSHIFTS, 010303 astronomy & astrophysics, COSMOS, Physics, maps, distances and redshift [Galaxies], Astrophysics::Instrumentation and Methods for Astrophysics, GALAXIES, observations -galaxies, Science policy, Christian ministry, Astrophysics::Earth and Planetary Astrophysics, Catalog, [SDU.ASTR.GA]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Galactic Astrophysics [astro-ph.GA], galaxies: distances and redshifts, Administration (government), Data release, Astrophysics - Cosmology and Nongalactic Astrophysics, photometric redshifts, Cosmology and Nongalactic Astrophysics (astro-ph.CO), Library science, FOS: Physical sciences, observation [Cosmology], Astrophysics::Cosmology and Extragalactic Astrophysics, STAR-FORMATION, surveys, 0103 physical sciences, distances and redshifts [Galaxies], Astrophysics::Galaxy Astrophysics, stellar, star-formation, 010308 nuclear & particles physics, Catalogs, Cosmology: observations, Galaxies: distances and redshifts, Astronomy and Astrophysics, cosmos, 115 Astronomy, Space science, Catalogues, Astrophysics - Astrophysics of Galaxies, STELLAR, 13. Climate action, [SDU]Sciences of the Universe [physics], Space and Planetary Science, Astrophysics of Galaxies (astro-ph.GA), cosmology: observations, Fundamental physics, catalogs -surveys -cosmology, catalogs
Abstract

The Complete Calibration of the Colour Redshift Relation survey (C3R2) is a spectroscopic effort involving ESO and Keck facilities designed specifically to empirically calibrate the galaxy colour redshift relation P(zjC) to the Euclid depth (iAB ≤ 24:5) and is intimately linked to the success of upcoming Stage IV dark energy missions based on weak lensing cosmology. The aim is to build a spectroscopic calibration sample that is as representative as possible of the galaxies of the Euclid weak lensing sample. In order to minimise the number of spectroscopic observations necessary to fill the gaps in current knowledge of the P(zjC), self-organising map (SOM) representations of the galaxy colour space have been constructed. Here we present the first results of an ESO@VLT Large Programme approved in the context of C3R2, which makes use of the two VLT optical and near-infrared multi-object spectrographs, FORS2 and KMOS. This data release paper focuses on high-quality spectroscopic redshifts of high-redshift galaxies observed with the KMOS spectrograph in the near-infrared H- and K-bands. A total of 424 highly-reliable redshifts are measured in the 1:3 ≤ z ≤ 2:5 range, with total success rates of 60.7% in the H-band and 32.8% in the K-band. The newly determined redshifts fill 55% of high (mainly regions with no spectroscopic measurements) and 35% of lower (regions with low-resolution/low-quality spectroscopic measurements) priority empty SOM grid cells. We measured Ha fluxes in a 100 : 2 radius aperture from the spectra of the spectroscopically confirmed galaxies and converted them into star formation rates. In addition, we performed an SED fitting analysis on the same sample in order to derive stellar masses, E(B - V), total magnitudes, and SFRs. We combine the results obtained from the spectra with those derived via SED fitting, and we show that the spectroscopic failures come from either weakly star-forming galaxies (at z < 1:7, i.e. in the H-band) or low S/N spectra (in the K-band) of z > 2 galaxies., he Euclid Consortium acknowledges the European Space Agency and the support of a number of agencies and institutes that have supported the development of Euclid. A detailed complete list is available on the Euclid website (http://www.euclid-ec.org). In particular the Academy of Finland, the Agenzia Spaziale Italiana, the Belgian Science Policy, the Canadian Euclid Consortium, the Centre National d’Etudes Spatiales, the Deutsches Zentrum für Luft-und Raumfahrt, the Danish Space Research Institute, the Fun-dação para a Ciênca e a Tecnologia, the Ministerio de Economia y Competi-tividad, the National Aeronautics and Space Administration, the Netherlandse Onderzoekschool Voor Astronomie, the Norvegian Space Center, the Romanian Space Agency, the State Secretariat for Education, Research and Innovation (SERI) at the Swiss Space Office (SSO), and the United Kingdom Space Agency. Based on observations collected at the European Southern Observatory under ESO programme 199.A-0732 (B,D,F,H). VG, RS, AG and RB acknowledge support by the Deutsches Zentrum f´ur Luft-und Raumfahrt (DLR) grant 50 QE 1101. FJC acknowledges support from the Spanish Ministry of Science, Innovation and Universities through grant ESP2017-89838-C3-1-R, and the H2020 programme of the European Commission through grant 776247. AG acknowledges a Sinergia grant from the Swiss National Science Foundation. SA thank the support PRIN MIUR 2015 “Cosmology and Fundamental Physics: Illuminating the Dark Universe with Euclid”.

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176. Tuning the solubility of hepta(p-benzamide)s via the monomer sequence

Author

Andreas F. M. Kilbinger and Helga Seyler

Subjects
chemistry.chemical_classification, 010405 organic chemistry, Organic Chemistry, Intermolecular force, Supramolecular chemistry, Peptide, 010402 general chemistry, 01 natural sciences, Biochemistry, 3. Good health, 0104 chemical sciences, chemistry.chemical_compound, Monomer, chemistry, Drug Discovery, Polymer chemistry, Side chain, Solubility, Benzamide, Benzoic acid
Abstract

The automated synthesis of hepta( p -benzamide) heterosequences on solid support using a modified peptide synthesizer is reported. The oligomers are synthesized from 4-aminobenzoic acid and 4-amino-2-(hexyloxy)benzoic acid, the latter carrying a solubilizing hexyl side chain. It is known from previous studies that both the unsubstituted hepta( p -benzamide) and the fully hexyloxy-substituted hepta( p -benzamide) are insoluble in all common organic solvents. Heterosequences in which both types of monomers alternate are, however, soluble in polar organic solvents such as DMSO. The heterosequence heptamers behave as strong organogelators when DMSO solutions are left at room temperature for several hours. Transmission electron microscopic (TEM) investigations revealed that the gelation was due to the oligomers forming long entangled fibers via a non-covalent aggregation mechanism. We explain these phenomena by a heterosequence triggered switch of aggregation mechanism. The unsubstituted oligomers strongly aggregate via a directional hydrogen-bond driven mechanism which changes to a less directional π-interaction driven aggregation mechanism for the substituted oligomers. We hereby demonstrate that designed heterosequences in non-natural oligoamides can lead to materials with distinctly different conformations which directly affect the intermolecular interactions and their supramolecular organization.

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177. Euclid: Effect of sample covariance on the number counts of galaxy clusters

Author

Ole Marggraf, Yu Wang, Marco Castellano, Emanuel Rossetti, S. Serrano, Natalia Auricchio, C. Padilla, Andrea Cimatti, Michele Moresco, Julien Zoubian, Felix Hormuth, A. Ealet, T. Vassallo, M. Poncet, Christopher J. Conselice, Sandrine Pires, D. Bonino, L. Popa, R. Cledassou, A. Fumagalli, S. Paltani, Roberto Scaramella, Emiliano Sefusatti, W. A. Holmes, Luigi Guzzo, F. Raison, K. Markovic, G. Zamorani, Jarle Brinchmann, Peter Schneider, Lauro Moscardini, Alexandro Saro, Lucia Pozzetti, Chiara Sirignano, G. Meylan, B. Garilli, M. Kilbinger, Simona Mei, Roberto P. Saglia, F. Grupp, Mauro Roncarelli, Rafael Toledo-Moreo, Andy Taylor, Elisabetta Maiorano, Pierluigi Monaco, I. Lloro, Pablo Fosalba, Martin Kunz, Massimo Meneghetti, L. Conversi, P. B. Lilje, Fabio Pasian, Adam Amara, F. Dubath, Valeria Pettorino, Richard Massey, Knud Jahnke, Carmelita Carbone, Leonardo Corcione, E. Franceschi, V. Capobianco, Stein Vidar Hagfors Haugan, Alina Kiessling, René J. Laureijs, Edwin A. Valentijn, M. Kümmel, G. Sirri, S. Dusini, C. Bodendorf, P. Franzetti, A. Balestra, S. M. Niemi, H. Degaudenzi, Tiago Castro, Stefano Cavuoti, Enzo Branchini, A. Secroun, Mark Cropper, Stefano Borgani, G. Seidel, Ismael Tereno, M. Fumana, Jason Rhodes, Hannu Kurki-Suonio, Thomas D. Kitching, Luca Valenziano, Anne Costille, G. Congedo, Jochen Weller, Marian Douspis, E. Munari, Henk Hoekstra, K. Pedersen, Massimo Brescia, M. Costanzi, Carlo Giocoli, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Centre National d'Études Spatiales [Toulouse] (CNES), Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Institut d'astrophysique spatiale (IAS), Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Centre National d’Études Spatiales [Paris] (CNES), Institut de Physique des 2 Infinis de Lyon (IP2I Lyon), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Astrophysique Interprétation Modélisation (AIM (UMR7158 / UMR_E_9005 / UM_112)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Euclid, Academy of Finland, Agenzia Spaziale Italiana, German Centre for Air and Space Travel, Danish Space Research Institute, Fundação para a Ciência e a Tecnologia (Portugal), Ministerio de Economía y Competitividad (España), National Aeronautics and Space Administration (US), Norwegian Space Agency, Romanian Space Agency, Swiss Space Office, UK Space Agency, Fumagalli, A., Saro, A., Borgani, S., Castro, T., Costanzi, M., Monaco, P., Munari, E., Sefusatti, E., Amara, A., Auricchio, N., Balestra, A., Bodendorf, C., Bonino, D., Branchini, E., Brinchmann, J., Capobianco, V., Carbone, C., Castellano, M., Cavuoti, S., Cimatti, A., Cledassou, R., Conselice, C. J., Corcione, L., Costille, A., Cropper, M., Degaudenzi, H., Douspis, M., Dubath, F., Dusini, S., Ealet, A., Fosalba, P., Franceschi, E., Franzetti, P., Fumana, M., Garilli, B., Giocoli, C., Grupp, F., Guzzo, L., Haugan, S. V. H., Hoekstra, H., Holmes, W., Hormuth, F., Jahnke, K., Kiessling, A., Kilbinger, M., Kitching, T., Kummel, M., Kunz, M., Kurki-Suonio, H., Laureijs, R., Lilje, P. B., Lloro, I., Maiorano, E., Marggraf, O., Markovic, K., Massey, R., Meneghetti, M., Meylan, G., Moscardini, L., Niemi, S. M., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Pettorino, V., Pires, S., Poncet, M., Popa, L., Pozzetti, L., Raison, F., Rhodes, J., Roncarelli, M., Rossetti, E., Saglia, R., Scaramella, R., Schneider, P., Secroun, A., Seidel, G., Serrano, S., Sirignano, C., Sirri, G., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Valentijn, E. A., Valenziano, L., Wang, Y., Weller, J., Zamorani, G., Zoubian, J., Brescia, M., Congedo, G., Conversi, L., Mei, S., Moresco, M., Vassallo, T., Astronomy, Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Astrophysique Interprétation Modélisation (AIM (UMR_7158 / UMR_E_9005 / UM_112)), Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Department of Physics, Helsinki Institute of Physics, Fumagalli A., Saro A., Borgani S., Castro T., Costanzi M., Monaco P., Munari E., Sefusatti E., Amara A., Auricchio N., Balestra A., Bodendorf C., Bonino D., Branchini E., Brinchmann J., Capobianco V., Carbone C., Castellano M., Cavuoti S., Cimatti A., Cledassou R., Conselice C.J., Corcione L., Costille A., Cropper M., Degaudenzi H., Douspis M., Dubath F., Dusini S., Ealet A., Fosalba P., Franceschi E., Franzetti P., Fumana M., Garilli B., Giocoli C., Grupp F., Guzzo L., Haugan S.V.H., Hoekstra H., Holmes W., Hormuth F., Jahnke K., Kiessling A., Kilbinger M., Kitching T., Kummel M., Kunz M., Kurki-Suonio H., Laureijs R., Lilje P.B., Lloro I., Maiorano E., Marggraf O., Markovic K., Massey R., Meneghetti M., Meylan G., Moscardini L., Niemi S.M., Padilla C., Paltani S., Pasian F., Pedersen K., Pettorino V., Pires S., Poncet M., Popa L., Pozzetti L., Raison F., Rhodes J., Roncarelli M., Rossetti E., Saglia R., Scaramella R., Schneider P., Secroun A., Seidel G., Serrano S., Sirignano C., Sirri G., Taylor A.N., Tereno I., Toledo-Moreo R., Valentijn E.A., Valenziano L., Wang Y., Weller J., Zamorani G., Zoubian J., Brescia M., Congedo G., Conversi L., Mei S., Moresco M., Vassallo T., ITA, USA, GBR, FRA, DEU, ESP, DNK, NLD, PRT, ROU, and CHE

Subjects
Cosmological parameter, statistical [Methods], bias, Large-scale structure of Universe, Gaussian, Astrophysics, clusters: general [Galaxies], 01 natural sciences, generation, galaxies, Statistical physics, clusters, dark energy, 010303 astronomy & astrophysics, Physics, Covariance matrix, Cosmological paremeters, Covariance, galaxies: clusters: general, symbols, impact, astro-ph.CO, large-scale structure of Universe, Likelihood function, Astrophysics - Cosmology and Nongalactic Astrophysics, Cosmology and Nongalactic Astrophysics (astro-ph.CO), FOS: Physical sciences, Context (language use), Astrophysics::Cosmology and Extragalactic Astrophysics, 114 Physical sciences, methods, symbols.namesake, 0103 physical sciences, Sample variance, halo mass function, cosmological parameters, Galaxy cluster, parameters, methods: statistical, model, 010308 nuclear & particles physics, Cosmological parameters, Galaxies: clusters: general, Methods: statistical, precision cosmology, Astronomy and Astrophysics, calibration, 115 Astronomy, Space science, Determining the number of clusters in a data set, general, Space and Planetary Science, cosmological constraints, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], statistical
Abstract

Fumagalli, A. et al. Euclid Consortium, [Aims] We investigate the contribution of shot-noise and sample variance to uncertainties in the cosmological parameter constraints inferred from cluster number counts, in the context of the Euclid survey., [Methods] By analysing 1000 Euclid-like light cones, produced with the PINOCCHIO approximate method, we validated the analytical model of Hu & Kravtsov (2003, ApJ, 584, 702) for the covariance matrix, which takes into account both sources of statistical error. Then, we used such a covariance to define the likelihood function that is better equipped to extract cosmological information from cluster number counts at the level of precision that will be reached by the future Euclid photometric catalogs of galaxy clusters. We also studied the impact of the cosmology dependence of the covariance matrix on the parameter constraints., [Results] The analytical covariance matrix reproduces the variance measured from simulations within the 10 percent; such a difference has no sizeable effect on the error of cosmological parameter constraints at this level of statistics. Also, we find that the Gaussian likelihood with full covariance is the only model that provides an unbiased inference of cosmological parameters without underestimating the errors, and that the cosmology-dependence of the covariance must be taken into account., SB, AS and AF acknowledge financial support from the ERC-StG ‘ClustersxCosmo’ grant agreement 716762, the PRIN-MIUR 2015W7KAWC grant, the ASI-Euclid contract and the INDARK grant. TC is supported by the INFN INDARK PD51 grant and by the PRIN-MIUR 2015W7KAWC grant. Our analyses have been carried out at: CINECA, with the projects INA17_C5B32 and IsC82_CosmGC; the computing center of INAF-Osservatorio Astronomico di Trieste, under the coordination of the CHIPP project (Bertocco et al. 2019; Taffoni et al. 2020). The Euclid Consortium acknowledges the European Space Agency and a number of agencies and institutes that have supported the development of Euclid, in particular the Academy of Finland, the Agenzia Spaziale Italiana, the Belgian Science Policy, the Canadian Euclid Consortium, the Centre National d’Etudes Spatiales, the Deutsches Zentrum für Luft- und Raumfahrt, the Danish Space Research Institute, the Fundação para a Ciência e a Tecnologia, the Ministerio de Economia y Competitividad, the National Aeronautics and Space Administration, the Netherlandse Onderzoekschool Voor Astronomie, the Norwegian Space Agency, the Romanian Space Agency, the State Secretariat for Education, Research and Innovation (SERI) at the Swiss Space Office (SSO), and the United Kingdom Space Agency. A complete and detailed list is available on the Euclid website (http://www.euclid-ec.org).

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179. Euclid preparation : XXIII. Derivation of galaxy physical properties with deep machine learning using mock fluxes and H-band images

Author

Collaboration, Euclid, Bisigello, L, Conselice, C J, Baes, M, Bolzonella, M, Brescia, M, Cavuoti, S, Cucciati, O, Humphrey, A, Hunt, L K, Maraston, C, Pozzetti, L, Tortora, C, van Mierlo, S E, Aghanim, N, Auricchio, N, Baldi, M, Bender, R, Bodendorf, C, Bonino, D, Branchini, E, Brinchmann, J, Camera, S, Capobianco, V, Carbone, C, Carretero, J, Castander, F J, Castellano, M, Cimatti, A, Congedo, G, Conversi, L, Copin, Y, Corcione, L, Courbin, F, Cropper, M, Da Silva, A, Degaudenzi, H, Douspis, M, Dubath, F, Duncan, C A J, Dupac, X, Dusini, S, Farrens, S, Ferriol, S, Frailis, M, Franceschi, E, Franzetti, P, Fumana, M, Garilli, B, Gillard, W, Gillis, B, Giocoli, C, Grazian, A, Grupp, F, Guzzo, L, Haugan, S V H, Holmes, W, Hormuth, F, Hornstrup, A, Jahnke, K, Kümmel, M, Kermiche, S, Kiessling, A, Kilbinger, M, Kohley, R, Kunz, M, Kurki-Suonio, H, Ligori, S, Lilje, P B, Lloro, I, Maiorano, E, Mansutti, O, Marggraf, O, Markovic, K, Marulli, F, Massey, R, Maurogordato, S, Medinaceli, E, Meneghetti, M, Merlin, E, Meylan, G, Moresco, M, Moscardini, L, Munari, E, Niemi, S M, Padilla, C, Paltani, S, Pasian, F, Pedersen, K, Pettorino, V, Polenta, G, Poncet, M, Popa, L, Raison, F, Renzi, A, Rhodes, J, Riccio, G, Rix, H -W, Romelli, E, Roncarelli, M, Rosset, C, Rossetti, E, Saglia, R, Sapone, D, Sartoris, B, Schneider, P, Scodeggio, M, Secroun, A, Seidel, G, Sirignano, C, Sirri, G, Stanco, L, Tallada-Crespí, P, Tavagnacco, D, Taylor, A N, Tereno, I, Toledo-Moreo, R, Torradeflot, F, Tutusaus, I, Valentijn, E A, Valenziano, L, Vassallo, T, Wang, Y, Zacchei, A, Zamorani, G, Zoubian, J, Andreon, S, Bardelli, S, Boucaud, A, Colodro-Conde, C, Ferdinando, D Di, Graciá-Carpio, J, Lindholm, V, Maino, D, Mei, S, Scottez, V, Sureau, F, Tenti, M, Zucca, E, Borlaff, A S, Ballardini, M, Biviano, A, Bozzo, E, Burigana, C, Cabanac, R, Cappi, A, Carvalho, C S, Casas, S, Castignani, G, Cooray, A, Coupon, J, Courtois, H M, Cuby, J, Davini, S, De Lucia, G, Desprez, G, Dole, H, Escartin, J A, Escoffier, S, Farina, M, Fotopoulou, S, Ganga, K, Garcia-Bellido, J, George, K, Giacomini, F, Gozaliasl, G, Hildebrandt, H, Hook, I, Huertas-Company, M, Kansal, V, Keihanen, E, Kirkpatrick, C C, Loureiro, A, Macías-Pérez, J F, Magliocchetti, M, Mainetti, G, Marcin, S, Martinelli, M, Martinet, N, Metcalf, R B, Monaco, P, Morgante, G, Nadathur, S, Nucita, A A, Patrizii, L, Peel, A, Potter, D, Pourtsidou, A, Pöntinen, M, Reimberg, P, Sánchez, A G, Sakr, Z, Schirmer, M, Sefusatti, E, Sereno, M, Stadel, J, Teyssier, R, Valieri, C, Valiviita, J, Viel, M, Astronomy, Euclid Collaboration, L. Bisigello, C. J. Conselice, M. Bae, M. Bolzonella, M. Brescia, S. Cavuoti, O. Cucciati, A. Humphrey, L. K. Hunt, C. Maraston, L. Pozzetti, C. Tortora, S. E. van Mierlo, N. Aghanim, N. Auricchio, M. Baldi, R. Bender, C. Bodendorf, D. Bonino, E. Branchini, J. Brinchmann, S. Camera, V. Capobianco, C. Carbone, J. Carretero, F. J. Castander, M. Castellano, A. Cimatti, G. Congedo, L. Conversi, Y. Copin, L. Corcione, F. Courbin, M. Cropper, A. Da Silva, H. Degaudenzi, M. Douspi, F. Dubath, C. A. J. Duncan, X. Dupac, S. Dusini, S. Farren, S. Ferriol, M. Fraili, E. Franceschi, P. Franzetti, M. Fumana, B. Garilli, W. Gillard, B. Gilli, C. Giocoli, A. Grazian, F. Grupp, L. Guzzo, S. V. H. Haugan, W. Holme, F. Hormuth, A. Hornstrup, K. Jahnke, M. Kümmel, S. Kermiche, A. Kiessling, M. Kilbinger, R. Kohley, M. Kunz, H. Kurki-Suonio, S. Ligori, P. B. Lilje, I. Lloro, E. Maiorano, O. Mansutti, O. Marggraf, K. Markovic, F. Marulli, R. Massey, S. Maurogordato, E. Medinaceli, M. Meneghetti, E. Merlin, G. Meylan, M. Moresco, L. Moscardini, E. Munari, S. M. Niemi, C. Padilla, S. Paltani, F. Pasian, K. Pedersen, V. Pettorino, G. Polenta, M. Poncet, L. Popa, F. Raison, A. Renzi, J. Rhode, G. Riccio, H. -W. Rix, E. Romelli, M. Roncarelli, C. Rosset, E. Rossetti, R. Saglia, D. Sapone, B. Sartori, P. Schneider, M. Scodeggio, A. Secroun, G. Seidel, C. Sirignano, G. Sirri, L. Stanco, P. Tallada-Crespí, D. Tavagnacco, A. N. Taylor, I. Tereno, R. Toledo-Moreo, F. Torradeflot, I. Tutusau, E. A. Valentijn, L. Valenziano, T. Vassallo, Y. Wang, A. Zacchei, G. Zamorani, J. Zoubian, S. Andreon, S. Bardelli A. Boucaud, C. Colodro-Conde, D. Di Ferdinando, J. Graciá-Carpio, V. Lindholm, D. Maino, S. Mei, V. Scottez, F. Sureau, M. Tenti, E. Zucca, A. S. Borlaff, M. Ballardini, A. Biviano, E. Bozzo, C. Burigana, R. Cabanac, A. Cappi, C. S. Carvalho, S. Casa, G. Castignani, A. Cooray, J. Coupon, H. M. Courtoi, J. Cuby, S. Davini, G. De Lucia, G. Desprez, H. Dole, J. A. Escartin, S. Escoffier, M. Farina, S. Fotopoulou, K. Ganga, J. Garcia-Bellido, K. George, F. Giacomini, G. Gozaliasl, H. Hildebrandt, I. Hook, M. Huertas-Company, V. Kansal, E. Keihanen, C. C. Kirkpatrick, A. Loureiro, J. F. Macías-Pérez, M. Magliocchetti, G. Mainetti, S. Marcin, M. Martinelli, N. Martinet, R. B. Metcalf, P. Monaco, G. Morgante, S. Nadathur, A. A. Nucita, L. Patrizii, A. Peel, D. Potter, A. Pourtsidou, M. Pöntinen, P. Reimberg, A. G. Sánchez, Z. Sakr, M. Schirmer, E. Sefusatti, M. Sereno, J. Stadel, R. Teyssier, C. Valieri, J. Valiviita, M. Viel, Bisigello, L., Conselice, C. J., Baes, M., Bolzonella, M., Brescia, M., Cavuoti, S., Cucciati, O., Humphrey, A., Hunt, L. K., Maraston11, C., Pozzetti, L., Tortora, C., van Mierlo, S. E., Aghanim, N., Auricchio, N., Baldi, M., Bender, R., Bodendorf, C., Bonino, D., Branchini, E., Brinchmann, J., Camera, S., Capobianco, V., Carbone, C., Carretero, J., Castander, F. J., Castellano, M., Cimatti, A., Congedo, G., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Cropper, M., Da Silva, A., Degaudenzi, H., Douspis, M., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Farrens, S., Ferriol, S., Frailis, M., Franceschi, E., Franzetti, P., Fumana, M., Garilli, B., Gillard, W., Gillis, B., Giocoli, C., Grazian, A., Grupp, F., Guzzo, L., Haugan, S. V. H., Holmes, W., Hormuth, F., Hornstrup, A., Jahnke, K., Kümmel, M., Kermiche, S., Kiessling, A., Kilbinger, M., Kohley, R., Kunz, M., Kurki-Suonio, H., Ligori, S., Lilje, P. B., Lloro, I., Maiorano, E., Mansutti, O., Marggraf, O., Markovic, K., Marulli, F., Massey, R., Maurogordato, S., Medinaceli, E., Meneghetti, M., Merlin, E., Meylan, G., Moresco, M., Moscardini, L., Munari, E., Niemi, S. M., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Pettorino, V., Polenta, G., Poncet, M., Popa, L., Raison, F., Renzi, A., Rhodes, J., Riccio, G., Rix, H. -W., Romelli, E., Roncarelli, M., Rosset, C., Rossetti, E., Saglia, R., Sapone, D., Sartoris, B., Schneider, P., Scodeggio, M., Secroun, A., Seidel, G., Sirignano, C., Sirri, G., Stanco, L., Tallada-Crespí, P., Tavagnacco, D., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valentijn, E. A., Valenziano, L., Vassallo, T., Wang, Y., Zacchei, A., Zamorani, G., Zoubian, J., Andreon, S., Boucaud, S. Bardelli A., Colodro-Conde, C., Di Ferdinando, D., Graciá-Carpio, J., Lindholm, V., Maino, D., Mei, S., Scottez, V., Sureau, F., Tenti, M., Zucca, E., Borlaff, A. S., Ballardini, M., Biviano, A., Bozzo, E., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Casas, S., Castignani, G., Cooray, A., Coupon, J., Courtois, H. M., Cuby, J., Davini, S., De Lucia, G., Desprez, G., Dole, H., Escartin, J. A., Escoffier, S., Farina, M., Fotopoulou, S., Ganga, K., Garcia-Bellido, J., George, K., Giacomini, F., Gozaliasl, G., Hildebrandt, H., Hook, I., Huertas-Company, M., Kansal, V., Keihanen, E., Kirkpatrick, C. C., Loureiro, A., Macías-Pérez, J. F., Magliocchetti, M., Mainetti, G., Marcin, S., Martinelli, M., Martinet, N., Metcalf, R. B., Monaco, P., Morgante, G., Nadathur, S., Nucita, A. A., Patrizii, L., Peel, A., Potter, D., Pourtsidou, A., Pöntinen, M., Reimberg, P., Sánchez, A. G., Sakr, Z., Schirmer, M., Sefusatti, E., Sereno, M., Stadel, J., Teyssier, R., Valieri, C., Valiviita111, J., Viel, M., Institut de Physique des 2 Infinis de Lyon (IP2I Lyon), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Astrophysique Interprétation Modélisation (AIM (UMR_7158 / UMR_E_9005 / UM_112)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Observatoire de la Côte d'Azur (OCA), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Centre National d'Études Spatiales [Toulouse] (CNES), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut d'Astrophysique de Paris (IAP), Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut de recherche en astrophysique et planétologie (IRAP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Etude du Rayonnement et de la Matière en Astrophysique (LERMA), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Centre de Calcul de l'IN2P3 (CC-IN2P3), and Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)

Subjects
FOS: Physical sciences, Euclid, Astronomy and Astrophysics, Astrophysics::Cosmology and Extragalactic Astrophysics, galaxies: general, galaxies: general, galaxies: photometry, galaxies: star formation, galaxies: evolution, Astrophysics - Astrophysics of Galaxies, Cosmology, galaxies: photometry, Physics and Astronomy, [SDU]Sciences of the Universe [physics], Space and Planetary Science, Astrophysics of Galaxies (astro-ph.GA), galaxies: star formation, photometry [galaxies], star formation [galaxies], galaxies: evolution, Astrophysics::Galaxy Astrophysics, evolution [galaxies], general [galaxies]
Abstract

Next generation telescopes, like Euclid, Rubin/LSST, and Roman, will open new windows on the Universe, allowing us to infer physical properties for tens of millions of galaxies. Machine learning methods are increasingly becoming the most efficient tools to handle this enormous amount of data, because they are often faster and more accurate than traditional methods. We investigate how well redshifts, stellar masses, and star-formation rates (SFR) can be measured with deep learning algorithms for observed galaxies within data mimicking the Euclid and Rubin/LSST surveys. We find that Deep Learning Neural Networks and Convolutional Neutral Networks (CNN), which are dependent on the parameter space of the training sample, perform well in measuring the properties of these galaxies and have a better accuracy than methods based on spectral energy distribution fitting. CNNs allow the processing of multi-band magnitudes together with $H_{\scriptscriptstyle\rm E}$-band images. We find that the estimates of stellar masses improve with the use of an image, but those of redshift and SFR do not. Our best results are deriving i) the redshift within a normalised error of less than 0.15 for 99.9$\%$ of the galaxies with S/N>3 in the $H_{\scriptscriptstyle\rm E}$-band; ii) the stellar mass within a factor of two ($\sim0.3 \rm dex$) for 99.5$\%$ of the considered galaxies; iii) the SFR within a factor of two ($\sim0.3 \rm dex$) for $\sim$70$\%$ of the sample. We discuss the implications of our work for application to surveys as well as how measurements of these galaxy parameters can be improved with deep learning., accepted for publication in MNRAS, 21 pages, 22 figures, 6 tables

Published
2023
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180. Cosmology with cosmic shear observations: a review.

Author

Kilbinger M

Subjects
Forecasting, Galaxies, Gravitation, Models, Theoretical, Optical Phenomena, Astronomy methods
Abstract

Cosmic shear is the distortion of images of distant galaxies due to weak gravitational lensing by the large-scale structure in the Universe. Such images are coherently deformed by the tidal field of matter inhomogeneities along the line of sight. By measuring galaxy shape correlations, we can study the properties and evolution of structure on large scales as well as the geometry of the Universe. Thus, cosmic shear has become a powerful probe into the nature of dark matter and the origin of the current accelerated expansion of the Universe. Over the last years, cosmic shear has evolved into a reliable and robust cosmological probe, providing measurements of the expansion history of the Universe and the growth of its structure. We review here the principles of weak gravitational lensing and show how cosmic shear is interpreted in a cosmological context. Then we give an overview of weak-lensing measurements, and present the main observational cosmic-shear results since it was discovered 15 years ago, as well as the implications for cosmology. We then conclude with an outlook on the various future surveys and missions, for which cosmic shear is one of the main science drivers, and discuss promising new weak cosmological lensing techniques for future observations.

Published
2015
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181. Virtual endoscopy combined with intraoperative neuronavigation for planning of endoscopic surgery in patients with occlusive hydrocephalus and intracranial cysts.

Author

Krombach GA, Rohde V, Haage P, Struffert T, Kilbinger M, and Thron A

Subjects
Adolescent, Adult, Aged, Brain Diseases diagnosis, Brain Diseases pathology, Cerebral Ventricles pathology, Child, Child, Preschool, Cysts diagnosis, Cysts pathology, Female, Humans, Hydrocephalus diagnosis, Hydrocephalus pathology, Imaging, Three-Dimensional, Infant, Intraoperative Period, Male, Middle Aged, Stereotaxic Techniques, User-Computer Interface, Brain Diseases surgery, Cysts surgery, Endoscopy, Hydrocephalus surgery, Magnetic Resonance Imaging
Abstract

We assessed the clinical value of MR ventriculoscopy (virtual endoscopy, VE) combined with image-guided frameless stereotaxy for endoscopic surgery of occlusive hydrocephalus and intracranial cysts. VE was obtained in 20 patients with hydrocephalus and three with intracranial cysts. All surgical operations were endoscopic. The path of the rigid endoscope to the target point was planned using neuronavigation. VE was carried out along the same trajectory retrospectively in 20 cases and prospectively in three. The results were analysed for demonstration of anatomical landmarks and structures at risk. VE was successful in all patients. Possible obstacles to endoscopic access to the lamina terminalis and the basal cisterns and structures at risk, such as the basilar artery, were clearly shown in relation to the direction of the endoscope. However, the floor of the third ventricle and septum pellucidum were not clearly seen and possible abnormalities could therefore not be appreciated. VE can provide realistic simulation of endoscopic third ventriculostomy and cystostomy. The appropriate trepanation point and trajectory of the endoscope can be assessed with regard to the size of the foramen of Monro and the position of vulnerable structures. This simulated trajectory can be adapted to the field of operation by image-guided neuronavigation. This regime may potentially reduce the risk of damage to intracranial structures.

Published
2002
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182. [Virtual endoscopy of the upper urinary tract based on contrast-enhanced MR urography data sets].

Author

Nolte-Ernsting CC, Krombach G, Staatz G, Kilbinger M, Adam GB, and Günther RW

Subjects
Adult, Aged, Child, Child, Preschool, Computer Systems, Contrast Media, Feasibility Studies, Female, Gadolinium DTPA, Humans, Image Processing, Computer-Assisted instrumentation, Kidney pathology, Male, Middle Aged, Sensitivity and Specificity, Ureter pathology, Image Enhancement instrumentation, Kidney Diseases diagnosis, Magnetic Resonance Imaging instrumentation, Ureteral Diseases diagnosis, Ureteroscopes, Urography instrumentation, User-Computer Interface
Abstract

Purpose: To investigate the feasibility of reconstructing a virtual endoscopy from MR imaging data sets of the upper urinary tract., Method: The data obtained from 28 contrast-enhanced MR urographic examinations (5 normal; 23 pathologic) were post-processed to reconstruct a virtual ureterorenoscopy (VURS) using a threshold image segmentation. The visualization of the upper urinary tract was based on the acquisition of T1-weighted 3D gradient-echo sequences after intravenous administration of gadolinium-DTPA and a prior injection of low-dose furosemide., Results: The employed MR urography technique created in all 28 cases a complete and strong contrast enhancement of the urinary tract. These 3D sequence data allowed the reconstruction of a VURS, even when the collecting system was not dilated. The best accuracy was provided by the MR urography sequences with the smallest voxel size. Moreover, the data acquisition based on a breath-hold technique has proved superior to that using a respiratory gating. Inside the renal pelvis, all calices could be assessed by turning the virtual endoscope in the appropriate direction. The visualization of the ureteral orifices in the bladder was also possible. All filling defects that were diagnosed by MR urography could be evaluated from the endoluminal view using the VURS. The exact characterization of the lesions based only on the assessment of the surface structure was difficult., Conclusion: A virtual endoscopy of the upper urinary tract can be successfully reconstructed using the data sets of high-resolution 3D MR urography sequences.

Published
1999
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183. Embolotherapy of aneurysms under temporary balloon occlusion of the neck. In vitro study of a newly designed eccentric balloon catheter.

Author

Schmitz-Rode T, Gülcan R, Kilbinger M, and Günther RW

Subjects
Embolization, Therapeutic methods, Equipment Design, Humans, Catheterization instrumentation, Embolization, Therapeutic instrumentation, Intracranial Aneurysm therapy
Abstract

Rationale and Objectives: To test embolotherapy of aneurysms in an in vitro model using standard and specially designed eccentric occlusion balloon catheters for simultaneous delivery of the embolization agent and occlusion of the neck of the aneurysm., Methods: Two different in vitro set-ups were used: a bifurcational aneurysm and an aneurysm with a straight parent vessel segment, both made from elastic silicone and glass. Each model was exposed to a pulsating perfusion. The effluent was collected and filtered. For the bifurcational aneurysms, commercially available occlusion balloon catheters with a working channel exiting at the tip were used. For the aneurysms with straight parent vessel, the catheters were modified so that the balloon opened eccentrically. The working channel of the catheter led to a side hole, which was located where the balloon membrane was fixed to the catheter shaft. The aneurysms were filled with coils, ethibloc, or hydrogel, and with coils combined with ethibloc or hydrogel, while the expanded balloon occluded the neck., Results: Embolization of aneurysms under balloon occlusion of the neck was technically feasible with the catheter devices. Dense packing with coils was possible in all cases without coil dislocation, but unfilled interspaces remained between the coil wires. Best filling was achieved with ethibloc or hydrogel alone or in combination with coils. During the filling procedure, there was no distal embolization of the liquid agents. However, after balloon deflation, considerable amounts of hydrogel or ethibloc were washed out from the aneurysm., Conclusions: The results suggest that balloon occlusion of the neck allows compact filling and minimizes the risk of dislocation in coil embolotherapy of aneurysms. In nonbifurcational aneurysms, the eccentric balloon catheter seems to be suitable for this treatment concept. Although liquid agents may be safely delivered into the aneurysm under balloon protection, their considerable washout rate after balloon removal requires further refinements of the technique before clinical application is advisable.

Published
1999
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184. [Repositioning of a central venous catheter with a guide wire with movable core].

Author

Schmitz-Rode T, Kilbinger M, and Günther RW

Subjects
Equipment Failure, Foreign-Body Migration diagnostic imaging, Foreign-Body Migration therapy, Humans, Phlebography instrumentation, Retreatment, Thorax blood supply, Catheterization, Central Venous instrumentation
Abstract

Purpose: A simple method to redirect malpositioned central venous catheters using a guide wire with movable core is described., Methods: A 0.89 mm guide wire with movable core is inserted into the catheter. The core is withdrawn for a few centimeters producing a floppy wire tip segment, which follows the malpositioned course of the catheter. The core is then advanced in small steps, until the catheter tip flips into the correct vein., Results: In 8 cases rapid repositioning of malpositioned catheters was accomplished with this technique, without moving the catheters at the entry site., Conclusions: The repositioning technique described is simple, fast, and inexpensive. Movement of the catheter at the entrance site is not necessary, thus not jeopardizing sterility, and without the need to solve the suture fixation.

Published
1999

185. Simulated flow pattern in massive pulmonary embolism: significance for selective intrapulmonary thrombolysis.

Author

Schmitz-Rode T, Kilbinger M, and Günther RW

Subjects
Angiography, Digital Subtraction, Animals, Catheterization, Contrast Media administration & dosage, Dogs, Fibrinolytic Agents administration & dosage, In Vitro Techniques, Microspheres, Pulmonary Artery diagnostic imaging, Pulmonary Embolism diagnostic imaging, Pulmonary Embolism therapy, Regional Blood Flow, Pulmonary Artery physiopathology, Pulmonary Embolism physiopathology
Abstract

Purpose: The flow pattern in the central pulmonary arteries proximal to large pulmonary emboli was studied experimentally. The currents to which thrombolytic agents are exposed when administered via an intrapulmonary catheter were visualized in order to explain the lack of benefit of local versus systemic administration., Methods: By illumination of suspended microspheres, the flow pattern proximal to an obstructing embolus was visualized in an in vitro pulmonary arterial flow model. In six dogs massive pulmonary embolism was created. A pigtail catheter was positioned in the pulmonary artery immediately proximal to the central edge of the occluding embolus. To allow visualization of the local flow pattern, a small amount of contrast material (4 ml) was injected through the catheter at a high flow rate (25 ml/sec). The course of the radiopaque spot that emerged from the catheter tip within 160 msec was monitored with digital subtraction angiography at a frame rate of 12.5 frames/sec. In two dogs, the study was repeated after embolus fragmentation with the same catheter position., Results: The flow model study revealed formation of a vortex proximal to the occluding embolus. In vivo experiments showed that the radiopaque spot was whirled by the vortex proximal to the embolus and made only evanescent contact with the edge of the embolus. Regardless of the embolus location, the contrast spot was washed into the non-occluded ipsilateral and contralateral pulmonary arteries within 0.40-0.64 sec. After embolus fragmentation, the contrast spot was carried completely into the formerly occluded artery., Conclusion: Flow studies explain why thrombolytic agents administered via a catheter positioned adjacent to the embolus may have no more effect than systemically administered agents. An enhanced local effect is precluded by the rapid washout into the non-occluded pulmonary arteries and subsequent systemic dilution. These results support the practice of direct intrathrombic injection of thrombolytics or local thrombolysis as an adjunct to embolus fragmentation.

Published
1998
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186. Bedside testing (SimpliRED) in the diagnosis of deep vein thrombosis. Evaluation of 250 patients.

Author

Wildberger JE, Vorwerk D, Kilbinger M, Piroth W, Hunter DW, Wienert V, and Günther RW

Subjects
Adolescent, Adult, Aged, Aged, 80 and over, False Positive Reactions, Female, Fibrin Fibrinogen Degradation Products analysis, Humans, Male, Middle Aged, Phlebography, Predictive Value of Tests, Prospective Studies, Sensitivity and Specificity, Point-of-Care Systems, Thrombophlebitis diagnosis
Abstract

Rationale and Objectives: The authors evaluate the sensitivity and specificity of a bedside test (SimpliRED) in the diagnosis of deep vein thrombosis compared with contrast phlebography., Methods: Two hundred fifty patients, referred for phlebography, underwent bedside testing for detection of deep vein thrombosis. Contrast phlebography was performed immediately afterward. SimpliRED provides a clearly visible agglutination of the patient's red blood cells in the presence of elevated levels of cross-linked fibrin derivative (D-dimer), which is specific for fibrin breakdown., Results: In 82 (32.8%) patients, deep vein thrombosis was confirmed venographically. An abnormal D-Dimer test was found in 79 of the 82 patients with thrombosis (sensitivity: 96.3%). The three patients who were diagnosed falsely as normal on agglutinin testing, had venograms which showed only an isolated calf thrombosis in small muscle veins (< 2 cm in diameter) not requiring treatment. One hundred of 168 patients without venographic thrombosis were diagnosed correctly by SimpliRED (specificity: 59.5%). The positive predictive value was 53.7%; the negative predictive value was 96.8%., Conclusions: All thrombotic disorders in the leg that required further treatment were identified correctly. SimpliRED is a very sensitive test with moderate specificity in the diagnosis of deep vein thrombosis. Therefore, further invasive testing is needed only in those patients in whom the D-dimer test is abnormal. A false-positive result of the bedside test may be nonspecific or due to elevated levels of fibrin split products, which can occur whenever the coagulation system has been activated by any of several conditions.

Published
1998
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187. [Cerebral sinus thrombosis: rapid test diagnosis by demonstration of increased plasma D-dimer levels (SimpliRED)].

Author

Wildberger JE, Mull M, Kilbinger M, Schön S, and Vorwerk D

Subjects
Adolescent, Adult, Child, Female, Hemagglutination, Humans, Male, Middle Aged, Reagent Kits, Diagnostic, Sensitivity and Specificity, Sinus Thrombosis, Intracranial blood, Time Factors, Fibrin Fibrinogen Degradation Products analysis, Sinus Thrombosis, Intracranial diagnosis
Abstract

Purpose: To perform an initial evaluation of the accuracy in detection of dural sinus and cerebral venous thrombosis using a bed-side test (SimpliRED)., Material and Methods: Early diagnosis and treatment of cerebral sinus thrombosis are important. A screening test to decide which patients should undergo further diagnostics would be valuable due to the low incidence. Six patients with MR proven cerebral sinus thrombosis underwent bed-side testing. The SimpliRED kit provides a clearly visible agglutination of the patient's red blood cells in the presence of elevated levels of the crosslinked fibrin derivative (D-dimer) in the sample., Results: The assay yielded a positive result in all six patients, even 56 days following the onset of clinical symptoms., Conclusion: The sensitivity of SimpliRED in the detection of sinus venous thrombosis is not known. This assay, therefore, should be evaluated in a large prospective study. In addition, the capability of the test to assess the effect of and predict the duration of anticoagulation therapy should be considered.

Published
1997
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188. [The diagnosis of deep venous thromboses of the leg using a new rapid test (SimpliRED)].

Author

Wildberger JE, Vorwerk D, Kilbinger M, Lentner A, Wienert V, and Günther RW

Subjects
Adult, Aged, Aged, 80 and over, Biomarkers blood, Female, Fibrin Fibrinogen Degradation Products analysis, Hematologic Tests methods, Humans, Male, Middle Aged, Phlebography, Prospective Studies, Sensitivity and Specificity, Hematologic Tests instrumentation, Point-of-Care Systems, Thrombophlebitis diagnosis
Abstract

Purpose: Evaluation of sensitivity and specificity of a bed-side test in the diagnosis of deep-vein thrombosis compared to contrast phlebography., Methods: 122 patients, referred for phlebography, underwent bedside testing (SimpliRED) for detection of deep vein thrombosis. Contrast phlebography was confirmed immediately afterwards. SimpliRED provides a clearly visible agglutination of the patient's red blood cells in the presence of elevated levels of crosslinked fibrin derivatives (D-dimer) in the sample, being specific for fibrin breakdown., Results: In 37 (30.3%) patients deep vein thrombosis could be confirmed. An abnormal D-dimer test was found in 35 of the 37 patients with thrombosis (sensitivity: 94.6%). Two patients who had not been identified by agglutinin testing, showed an isolated calf thrombosis in small muscle veins (< 2 cm in diameter) not requiring treatment. 55 of 85 patients without thrombosis in phlebography were stated correctly by SimpliRED (specificity: 64.7%)., Conclusion: All thrombotic disorders in the leg with the need for further treatment were identified correctly. SimpliRED is a very sensitive test with moderate specificity in the diagnosis of deep vein thrombosis. Therefore, further invasive testing is needed only in such patients where the D-dimer test is abnormal. A false positive result of the bed-side test may be non-specific or due to elevated levels of fibrin split products, if the coagulation system is activated in several other conditions.

Published
1997
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189. [Osteoporotic stress fractures of the sacrum: MR-tomography findings].

Author

Staatz G, Adam G, Kilbinger M, and Günther RW

Subjects
Aged, Aged, 80 and over, Contrast Media, Drug Combinations, Female, Gadolinium, Gadolinium DTPA, Humans, Magnetic Resonance Imaging methods, Male, Meglumine, Middle Aged, Organometallic Compounds, Osteoporosis pathology, Pentetic Acid analogs & derivatives, Tomography, X-Ray Computed, Fractures, Stress pathology, Osteoporosis complications, Sacrum injuries, Sacrum pathology
Abstract

Purpose: Evaluation of the morphologic appearance of sacral osteoporotic insufficiency fractures in MRI., Patients and Method: 6 patients (5 female and one male, 54-80 years) with osteoporotic insufficiency fractures of the sacrum were examined with CT and MRI. Plain and contrast-enhanced T1- and T2-weighted spin-echo images were acquired, three patients were studied with T1-weighted gradient-echo-sequences with fat suppression., Results: Fracture-lines and sclerotic areas of the massae laterales were visible in 5 of 6 CT examinations, one patient showed no abnormalities of the sacrum on the initially performed CT scans. All patients had a diffuse bone marrow oedema of the fractured massae laterales with a decreased signal on the T1-weighted spin-echo images and an increased signal on the T1-weighted gradient-echo images with fat suppression and in the T2-weighted SE-sequences. Gadopentate dimeglumine enhanced MRI images showed a remarkable diffuse configurated high signal of the whole sacrum in bilateral fractures (H-pattern). An additional soft tissue mass could be excluded in each case., Conclusion: Gadopentate dimeglumine enhanced MRI of sacral insufficiency fractures allows early diagnosis and helps to exclude intraosseous tumour formation.

Published
1997
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190. [Goals, requirements and prerequisites of teleradiology. An assessment of current status].

Author

Walz M, Wein B, Lehmann KJ, Bolte R, Kilbinger M, Loose R, Günther RW, and Georgi M

Subjects
Forecasting, Germany, Goals, Humans, Medical Records Systems, Computerized legislation & jurisprudence, Medical Records Systems, Computerized trends, Quality Assurance, Health Care legislation & jurisprudence, Quality Assurance, Health Care trends, Teleradiology legislation & jurisprudence, Teleradiology trends
Abstract

Specific radiological requirements have to be considered for the realization of telemedicine. In this article the goals and requirements for an extensive introduction of teleradiology will be defined from the radiological user's point of view. Necessary medical, legal and professional prerequisites for teleradiology are presented. Essential requirements, such as data security, maintenance of personal rights and standardization, must be realized. Application-specific requirements, e.g. quality and extent of teleradiological functions, as well as technological alternatives, are discussed. Each project must be carefully planned in relation to one's own needs, extent of functions and system selection. Topics, such as acknowledgement of electronic documentation, reimbursement of teleradiology and liability, must be clarified. Legal advice and the observance of quality guidelines are recommended.

Published
1997

191. Guidelines for cost-effective implementation of Picture Archiving and Communication Systems. An approach building on practical experiences in three European hospitals.

Author

van Gennip EM, Enning J, Fischer F, Glaser KH, Kilbinger M, Klose KJ, List-Hellwig E, Van der Loo R, Rechid R, Van den Broeck R, and Wein B

Subjects
Cost-Benefit Analysis, Europe, Evaluation Studies as Topic, Hospital Costs, Intensive Care Units, Software, Systems Integration, Tomography, X-Ray Computed, Ultrasonography, Radiology Information Systems economics
Abstract

This paper describes a comprehensive approach for the assessment of the impact of (partial) Picture Archiving and Communication Systems (PACS). The approach is developed, based on actual clinical experience in three European hospitals and tested in these environments. The approach departs from a thorough analysis of the working procedures and information flows before implementation, both descriptive and quantitative. On the basis of this analysis, quantitative (and hence testable) objectives of the implementation are defined. The implementation strategy is defined after comparison of various scenarios, taking costs and effects for both the final and the transition phases into account. The approach is supported by a comprehensive evaluation protocol and a software package (PACER). The approach is demonstrated in this paper by applying it on a hypothetical PACS implementation for CT, ultrasound and for the part of the radiology department serving ICU. The objectives of this PACS are: (1)--to shorten the turn around time between the radiology department and ICU from 4 h to 30 min, (2)--to save 2000 m2 of film per year and (3)--to save personnel time. In this case the PACS is introduced in three phases and completed after three years. The cost analysis shows that, if started in 1995, a financial break even point is reached after 6 years, when comparing costs for the film-based system with those of the PACS. Experiences in the three sites show that the approach helps to harvest potential benefits, allowing a cost-effective implementation of PACS.

Published
1996
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192. Differentiation of spontaneous canine breast tumors using dynamic magnetic resonance imaging with 24-Gadolinium-DTPA-cascade-polymer, a new blood-pool agent. Preliminary experience.

Author

Adam G, Mühler A, Spüntrup E, Neuerburg JM, Kilbinger M, Bauer H, Fücezi L, Küpper W, and Günther RW

Subjects
Adenoma surgery, Animals, Carcinoma surgery, Dog Diseases surgery, Dogs, Drug Combinations, Female, Gadolinium DTPA, Infusions, Intravenous, Mammary Neoplasms, Animal surgery, Meglumine, Polymers, Retrospective Studies, Adenoma diagnosis, Carcinoma diagnosis, Contrast Media, Dog Diseases diagnosis, Magnetic Resonance Imaging, Mammary Neoplasms, Animal diagnosis, Organometallic Compounds, Pentetic Acid analogs & derivatives
Abstract

Rationale and Objectives: The author assess the enhancement characteristics over time of spontaneous breast tumors in dogs comparing gadopentetate dimeglumine with a new blood-pool agent (24-gadolinium [Gd]-DTPA-cascade polymer)., Methods: Eighteen dogs with spontaneous breast tumors (5 carcinomas, 4 adenomas, and 9 benign mixed-tissue tumors) underwent dynamic magnetic resonance imaging after intravenous injection of gadopentetate dimeglumine and the blood-pool agent. Signal intensity time curves were followed up to 30 minutes after injection of both agents in the same animal. A nonlinear fitting routine enabled calculation of the delivery and clearance half lives of the contrast agent kinetics in each tumor., Results: For gadopentetate dimeglumine, a fast signal increase was found immediately after intravenous injection, with a subsequent signal decay in all tumors. No difference was observed between the enhancement kinetics of different tumor types after gadopentetate dimeglumine application. Similar kinetics were found in benign lesions after injection of the blood-pool agent. However, in carcinomas the blood-pool agent displayed a slower delivery, delayed peak enhancement, and slower tumor tissue clearance or even a signal plateau of more than 30 minutes., Conclusions: Dynamic magnetic resonance imaging of breast neoplasms using a blood-pool agent may help to better differentiate between benign and malignant lesions because it demonstrates the enlarged interstitial space and increased capillary permeability in carcinomas.

Published
1996
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193. Fragmentation of pulmonary emboli: in vivo experimental evaluation of two high-speed rotating catheters.

Author

Schmitz-Rode T, Adam G, Kilbinger M, Pfeffer J, and Günther SB

Subjects
Animals, Dogs, Embolectomy adverse effects, Embolectomy methods, Equipment Design, Pulmonary Artery diagnostic imaging, Pulmonary Artery surgery, Pulmonary Embolism diagnostic imaging, Radiography, Embolectomy instrumentation, Pulmonary Embolism surgery
Abstract

Purpose: To test two over-the-wire systems for fragmentation of pulmonary emboli., Methods: In 11 dogs, 22 embolic occlusions of lobar or central pulmonary arteries were performed by injection of preformed emboli through a jugular vein sheath. A commercially available device (thrombolizer) and a modified version of the impeller catheter were introduced via the femoral vein and positioned at the embolus site., Results: Catheter placement at the site of the emboli was possible. In more than half of the cases a hydrophilic or an extra-stiff guidewire was necessary. The thrombolizer did not rotate properly with its original pneumatic drive and required a major modification. When sufficient rotation was provided, both fragmentation catheters were able to clear the occluded main arteries. Side branches were partly obstructed by the resulting fragments. Recanalization led to a reduction of the emboli-induced elevation of the pulmonary arterial pressure by two-thirds. Histology of the recanalized pulmonary artery segments revealed localized (impeller catheter) and widespread (thrombolizer) periarterial hemorrhage., Conclusion: Embolus fragmentation led to a hemodynamic improvement. The impeller catheter was less traumatic compared with the thrombolizer, which was technically insufficient.

Published
1996

194. [Detectability of focal liver lesions: comparison of MRI at 1.5 T and dynamic spiral CT].

Author

Urhahn R, Adam G, Keulers P, Kilbinger M, and Günther RW

Subjects
Adenoma, Liver Cell diagnosis, Adenoma, Liver Cell pathology, Fatty Liver diagnosis, Fatty Liver pathology, Hemangioma diagnosis, Hemangioma pathology, Humans, Hyperplasia diagnosis, Hyperplasia pathology, Image Processing, Computer-Assisted, Liver pathology, Liver Diseases pathology, Liver Neoplasms pathology, Observer Variation, Retrospective Studies, Sensitivity and Specificity, Liver Diseases diagnosis, Liver Neoplasms diagnosis, Magnetic Resonance Imaging instrumentation, Tomography, X-Ray Computed instrumentation
Abstract

Purpose: To compare dynamic spiral CT with MR imaging in the detectability of focal liver lesions., Material and Methods: Thirty-one patients with 62 focal liver lesions (27 benign) were evaluated retrospectively. Dynamic spiral CT scans were compared with T1- and T2- weighted spin-echo (SE) sequences and in part with multi slice 2-D-FLASH and single-shot slice-selective inversion recovery Turbo-FLASH sequences at 1.5 T., Results: Dynamic spiral CT detected 89% of all lesions and was superior to each sequence alone (56-70%), and also to MRI overall (79%) regardless of lesion size, localization, and histology. However, statistical significance (p < 0.05) was only found for the differences between CT and the T1-weighted SE sequence., Conclusion: Compared to conventional SE and GE MR imaging sequences, dynamic spiral CT scanning seems to be more effective in the detection of focal liver lesions.

Published
1996
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195. Dynamic Gd-enhanced MR imaging of hepatic hemangioma: is high temporal resolution requisite for characterization?

Author

Urhahn R, Kilbinger M, Drobnitzky M, Mans-Peine G, Neuerburg J, and Günther RW

Subjects
Gadolinium, Gadolinium DTPA, Humans, Image Enhancement, Contrast Media, Hemangioma diagnosis, Liver Neoplasms diagnosis, Magnetic Resonance Imaging, Organometallic Compounds, Pentetic Acid analogs & derivatives
Abstract

We assessed the value of high temporal resolution in the dynamic characterization of hepatic hemangioma with use of magnetization-prepared gradient-echo (MP-GRE) imaging. Single-level inversion recovery incremental flip angle MP-GRE images were obtained in 26 patients with 34 hemangiomas before and at a repetition rate of 30 images/min after injection of Gd-DTPA without breath-holding. Enhancement patterns and temporal changes thereof were analyzed. Hemangiomas were categorized as small ( < 2.0 cm), medium (2.0-5.0 cm), and large ( > 5 cm) lesions. Classic early peripheral nodular enhancement (PNE) with progressive hyperintense fill-in was observed in 31 lesions (91%). Two of 10 small and 1 of 20 medium lesions showed complete fill-in within 10 s, and three small and one medium lesions within 45 s after the onset of PNE. In no cases of hemangioma was immediate homogenous hyperintensity observed without preceding PNE. In conclusion, temporal resolution of less than 10 s is a prerequisite for confident dynamic characterization of some hemangiomas, predominantly small hemangiomas.

Published
1996
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196. [The diagnosis of acute pulmonary embolism: a comparison between spiral CT and DSA in an animal experiment].

Author

Schmitz-Rode T, Kilbinger M, Adam G, and Günther RW

Subjects
Acute Disease, Animals, Disease Models, Animal, Dogs, Evaluation Studies as Topic, Observer Variation, Pulmonary Artery diagnostic imaging, Angiography, Digital Subtraction instrumentation, Angiography, Digital Subtraction methods, Pulmonary Embolism diagnostic imaging, Tomography, X-Ray Computed instrumentation, Tomography, X-Ray Computed methods
Abstract

Purpose: The value of helical computed tomography (CT) for diagnosis of acute pulmonary embolism was assessed and compared with digital subtraction angiography (DSA) as a reference method., Material and Methods: In 11 dogs, lobar, segmental, and subsegmental occlusions of the pulmonary arteries were produced. Subsequent to selective pulmonary angiography, the animals were examined with contrast-enhanced helical CT., Results: In the main and lobar pulmonary arteries there was a complete correlation between CT and DSA in documentation of total and partial embolic occlusions. Identification of segmental and subsegmental pulmonary emboli by CT required a second run with optimized parameters in 7 of 11 cases. Nevertheless, 18% of the peripheral arteries could not be classified., Conclusion: Helical CT as less invasive modality is competitive with DSA in demonstration of central pulmonary emboli. However, CT imaging of peripheral pulmonary emboli requires optimal bolus timing.

Published
1995
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197. [The MR tomography of avascular necrosis of bone: the primary findings and the follow-up observations after core decompression].

Author

Adam G, Keulers P, Forst J, Neuerburg J, Kilbinger M, and Günther RW

Subjects
Adult, Aged, Female, Femur Head diagnostic imaging, Femur Head pathology, Femur Head surgery, Femur Head Necrosis diagnosis, Femur Head Necrosis surgery, Follow-Up Studies, Humans, Humerus diagnostic imaging, Humerus pathology, Humerus surgery, Male, Middle Aged, Osteonecrosis surgery, Postoperative Period, Prospective Studies, Radiography, Bone Marrow surgery, Magnetic Resonance Imaging instrumentation, Magnetic Resonance Imaging methods, Osteonecrosis diagnosis
Abstract

Purpose: To assess the signal changes of avascular bone necrosis after core decompression., Patients and Methods: 17 patients with avascular epiphyseal necrosis were examined by MRI using T1-weighted spin echo sequences before and after gadopentetate dimeglumine application, T2-weighted spin echo sequences and in some patients with fat-saturated 2D gradient echo sequences up to 22 months after core decompression., Results: All patients but one recovered from symptoms after core decompression. Although the signal morphology of the necrotic area remained unchanged in the majority of the cases, a decrease of the joint effusion was observed as well as an ongoing signal increase after gadopentetate dimeglumine application. The last examinations displayed similar signal characteristics as on the preoperative scans; however, a reduction of the necrotic zone became evident., Conclusions: The decrease of joint effusion indicates successful core decompression, while a persistent signal increase after gadopentetate dimeglumine application reflects the viability of the necrotic area as well as an ongoing healing process.

Published
1995
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198. [Intrarenal duplex sonography in detecting flow changes after renal PTA].

Author

Vorwerk D, Speckamp F, Schürmann K, Rückforth J, Kilbinger M, and Günther RW

Subjects
Adolescent, Adult, Aged, Aged, 80 and over, Angiography, Digital Subtraction, Child, Female, Humans, Kidney physiopathology, Male, Middle Aged, Renal Artery diagnostic imaging, Renal Artery physiopathology, Renal Artery Obstruction diagnostic imaging, Renal Artery Obstruction physiopathology, Renal Artery Obstruction therapy, Ultrasonography, Doppler, Color instrumentation, Ultrasonography, Doppler, Color methods, Angioplasty, Balloon, Kidney diagnostic imaging, Renal Circulation
Abstract

Purpose: Changes of the intrarenal Doppler signal were analysed before and after renal balloon dilatation to assess the technical success of PTRA., Materials and Method: In 33 patients, intrarenal Doppler signal was depicted before and after renal PTA. Doppler flow curve was analysed by using the acceleration index (AI), acceleration time index (AT) and resistance index (RI); for all indices side ratios (AI-R, AT-R and RI-R) were calculated. Balloon dilatation was angiographically successful in all cases. Average stenosis graded 71% before and 21% after PTA., Results: By definition of limits for all indices used, a single patient was graded as non-stenotic before balloon dilatation by application of AI/AI-R and no patient was graded nonstenotic by AI/RI-R. After renal PTA, all indices significantly changed towards normal findings and by application of both AI/AI-R and AI/RI-R, only a single patient was graded stenotic after PTA., Conclusion: Intrarenal Doppler signal analysis reliably allows to detect flow changes following renal PTA in patients with renal artery stenosis. It may therefore be used as a noninvasive method to monitor flow improvement after renal PTA and during follow-up.

Published
1995
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199. [Color-coded duplex ultrasonography in the diagnosis of renal artery stenosis].

Author

Speckamp F, Vorwerk D, Schürmann K, Risse JH, Kilbinger M, Tacke J, and Günther RW

Subjects
Adolescent, Adult, Aged, Aged, 80 and over, Angiography, Digital Subtraction, Child, Diagnosis, Differential, Evaluation Studies as Topic, Female, Humans, Male, Middle Aged, Sensitivity and Specificity, Renal Artery Obstruction diagnostic imaging, Ultrasonography, Doppler, Color
Abstract

Purpose: Colour-coded duplex sonography was performed for diagnosis of renal artery stenosis to define standards and criteria for stenosis., Material and Methods: In 20 normotensive volunteers and 123 patients with arterial hypertension, bilateral intrarenal Doppler spectra were examined and the following parameters including side ratios were calculated: pulsatility index (PI), resistance index (RI), acceleration time index (AT) and acceleration index (AI)., Results: In 29 of the 123 patients, angiography showed unilateral renal artery stenosis. Acceleration index (AI) was found as the most reliable parameter with a sensitivity of 100% and a specificity of about 94% for stenoses grading at least 70%., Conclusions: Colour-coded duplex sonography can depict relevant stenoses reliably, but anatomical variations may limit its value as a single screening method. Colour-coded duplex sonography can be, therefore, recommended as an adjunct to angiography for assessment of haemodynamic relevance.

Published
1995
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