Search

Your search keyword '"Luft, R."' showing total 614 results
Start Over Author "Luft, R."
614 results on '"Luft, R."'

159. Die Beziehungen zwischen Hypophysenvorderlappen und Diabetes mellitus im Tierversuch

Author

Liebermeister, H., Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

160. Die Stoffwechselwirkungen des Insulins

Author

Löffler, Georg, Weiss, Ludwig, Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

161. Die Stoffwechselwirkungen des Glukagon

Author

Leclercq-Meyer, Viviane, Malaisse, Willy J., Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

162. Die Stoffwechselwirkungen der Schilddrüsenhormone

Author

Dieterle, P., Scriba, P. C., Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

163. Die Immunologie des Insulins

Author

Kerp, L., Henrichs, H. R., Kasemir, H., Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

164. Die Chemie des Insulins

Author

Schlichtkrull, J., Ege, H., Jørgensen, K. H., Markussen, J., Sundby, F., Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

165. Die normale und pathologische Morphologie des Inselsystems

Author

Gepts, W., Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

166. Einteilung und Vorstadien des Diabetes mellitus

Author

Jahnke, K., Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

167. Die Genetik des idiopathischen Diabetes

Author

Jörgensen, Gerhard, Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

168. Die Sekretion des Insulins. Stimulierung und Hemmung

Author

Frerichs, H., Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

169. Gravidität und Diabetes

Author

Hoet, J., Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

170. Der kindliche Diabetes

Author

Hungerland, Heinz, Möllering, Margarete, Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

171. Klinik des Diabetes mellitus

Author

Jahnke, K., Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

172. Die Geschichte des Diabetes mellitus

Author

Schadewaldt, Hans, Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

173. Der experimentelle Diabetes

Author

Usadel, K. H., Schwedes, U., Schöffling, K., Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

174. Die Diagnostik des Diabetes

Author

Englhardt, A., Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

175. Das Wachstumshormon und die Entwicklung der diabetischen Gefäßkrankheit

Author

Cerasi, Erol, Luft, Rolf, Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

176. Die Epidemiologie des Diabetes

Author

Jarrett, R. J., Keen, H., Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

177. Die Ätiologie und Pathogenese des Diabetes

Author

Cerasi, Erol, Luft, Rolf, Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

178. Die spontan-diabetischen Tiere

Author

Herberg, Lieselotte, Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

179. Stoffwechselwirkungen der Katecholamine

Author

Hasselblatt, A., Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

180. Die Wirkungen der Corticosteroide auf den Kohlenhydratstoffwechsel

Author

Zimmermann, H., Schwiegk, H., editor, Cerasi, E., editor, Dieterle, P., editor, Ege, H., editor, Englhardt, A., editor, Frerichs, H., editor, Gepts, W., editor, Hasselblatt, A., editor, Henrichs, H. R., editor, Herberg, L., editor, Hoet, J. J., editor, Hungerland, H., editor, Jahnke, K., editor, Jarrett, R. J., editor, Jörgensen, G., editor, Jørgensen, K. H., editor, Kasemir, H., editor, Keen, H., editor, Kerp, L., editor, Leclercq-Meyer, V., editor, Liebermeister, H., editor, Löffler, G., editor, Luft, R., editor, Malaisse, W. J., editor, Markussen, J., editor, Möllering, M., editor, Schadewaldt, H., editor, Schlichtkrull, J., editor, Schöffling, K., editor, Schwedes, U., editor, Scriba, P. C., editor, Sundby, F., editor, Usadel, K.-H., editor, Weiss, L., editor, Zimmermann, H., editor, and Oberdisse, Karl, editor

Published
1975
Full Text
View/download PDF

183. Population influences desiccation tolerance in an invasive aquatic snail, Potamopyrgus antipodarum (Tateidae, Mollusca).

Author

Levri EP, Hutchinson S, Luft R, Berkheimer C, and Wilson K

Subjects
Animals, Genotype, Phenotype, Mollusca, Desiccation, Food
Abstract

Traits in species that influence invasion success may vary in populations across its invaded range. The aquatic New Zealand mud snail, Potamopyrgus antipodarum , reproduces parthenogenetically in its invaded range, and a few distinct clonal genotypes have been identified in North America. Much of the spread of the snail in North America has been the result of unintentional overland transport by recreational water users. Thus, desiccation tolerance may play an important role in the invasion success of this species. The primary goal of these experiments is to determine if variation in desiccation tolerance exists between populations of this species. Here we compared multiple multi-locus genotypes (MLGs) and populations within those genotypes with regard to their desiccation tolerance. We conducted three experiments. The first compared the survival rate over time of snails from three populations and two MLGs with regard to their ability to survive being completely removed from water. The second experiment examined different size classes of snails from the same population, and the third experiment compared four different populations and two MLGs genotypes with respect to their survival rate over time when removed from water but being kept in moist conditions. We found larger snails tolerate desiccation longer than smaller snails with snails between 4 and 4.6 mm surviving at a rate of more than 50% after 12 h while smaller snails survived at a less than 5% rate after 12 h. We also found significant variation both between and within MLGs in their survival rate when completely removed from water and dried with the MLG from the western US having a more than 50% greater survival probability than the eastern MLGs at both 18 and 24 h out of water. When removed from water and kept moist all MLGs had a near 100% survival rate at 60 days at 7 °C, and most survived at a greater than 90% rate at 60 days at 17 °C, while no MLG's survived past 30 days at 27 °C. The results demonstrate that variation for desiccation tolerance exists between populations of this invader which could influence the invasiveness of different populations., Competing Interests: The authors declare that they have no competing interests., (© 2023 Levri et al.)

Published
2023
Full Text
View/download PDF

184. Sound Transmission Loss of a Sandwich Plate with Adjustable Core Layer Thickness.

Author

Ehrig T, Dannemann M, Luft R, Adams C, Modler N, and Kostka P

Abstract

Compressible Constrained Layer Damping (CCLD) is a novel, semi-active, lightweight-compatible solution for vibration mitigation based on the well-known constrained layer damping principle. The sandwich-like CCLD set-up consists of a base structure, a constraining plate, and a compressible open-cell foam core in between, enabling the adjustment of the structure's vibration behaviour by changing the core compression using different actuation pressures. The aim of the contribution is to show to what degree, and in which frequency range the acoustic behaviour can be tuned using CCLD. Therefore, the sound transmission loss (TL), as an important vibro-acoustic index, is determined in an acoustic window test stand at different actuation pressures covering a frequency range from 0.5 to 5 kHz. The different actuation pressures applied cause a variation of the core layer thickness (from 0.9 d 0 to 0.3 d 0 ), but the resulting changes of the stiffness and damping of the overall structure have no significant influence on the TL up to approximately 1 kHz for the analysed CCLD design. Between 1 kHz and 5 kHz, however, the TL can be influenced considerably well by the actuation pressure applied, due to a damping-dominated behaviour around the critical frequency.

Published
2020
Full Text
View/download PDF

185. Mitochondrial medicine.

Author

Luft R and Landau BR

Subjects
Adenosine Triphosphate metabolism, Adult, Aged, Animals, Antioxidants, Cardiovascular Diseases etiology, Central Nervous System Diseases etiology, Child, Diabetes Mellitus, Type 1 etiology, Electron Transport, Female, Forecasting, Free Radicals, Humans, Male, Middle Aged, Models, Biological, Mutation, Nervous System Diseases etiology, Oxidants, Oxidative Phosphorylation, Rats, Risk Factors, Aging genetics, DNA, Mitochondrial genetics, Mitochondria genetics, Mitochondria metabolism
Abstract

In the mitochondrion, inherited defects have been identified in the electron transport system by which ATP is formed, as well as in the transport and metabolism of fuels. Clinical findings in diseases due to these defects can be related to abnormal accumulations of metabolic intermediates and inadequate or inefficient ATP generation. In the oxidative process within the mitochondrion, chemical oxidants are generated, which can cause cellular damage. As the body's defences against the oxidants decline, oxidative damage appears to contribute to the ageing process itself as well as to age-related degenerative diseases. Understanding in this area has accelerated with knowledge of the synthesis, structure and function of the mitochondrion and its specific DNA. The frontier is expected to advance rapidly as causal relationships between these diseases and mitochondrial dysfunction, and the potential role of antioxidants in therapy, are better defined.

Published
1995
Full Text
View/download PDF

186. The development of mitochondrial medicine.

Author

Luft R

Subjects
Aging metabolism, Animals, Antioxidants pharmacology, Central Nervous System metabolism, DNA, Mitochondrial genetics, DNA, Mitochondrial metabolism, Diabetes Mellitus, Type 2 metabolism, Free Radicals metabolism, Humans, Mitochondrial Encephalomyopathies genetics, Mitochondrial Myopathies genetics, Organ Specificity, Mitochondria metabolism, Mitochondrial Myopathies metabolism
Abstract

I consider mitochondrial medicine a tentative designation for an area within clinical medicine still to be delineated. Its development extends over a period of 35 years, from its discovery in 1959 [1]. Progress had been gradual until recent years when it has become explosive in nature with extensions in many different directions. My presentation is an effort to illustrate this evolution with emphasis on especially important observations which by leaps advanced the area. We are fortunate to have here several of the distinguished investigators, who have contributed so much to those advances. They will share with us their deep knowledge in different aspects of mitochondrial medicine, what is known, what remains to be elucidated, and what the problems are to be encountered in that elucidation.

Published
1995
Full Text
View/download PDF

187. The development of mitochondrial medicine.

Author

Luft R

Subjects
Aging, Humans, Mitochondrial Encephalomyopathies, Oxidative Phosphorylation, DNA, Mitochondrial genetics, Mitochondria physiology, Mitochondrial Myopathies
Abstract

Primary defects in mitochondrial function are implicated in over 100 diseases, and the list continues to grow. Yet the first mitochondrial defect--a myopathy--was demonstrated only 35 years ago. The field's dramatic expansion reflects growth of knowledge in three areas: (i) characterization of mitochondrial structure and function, (ii) elucidation of the steps involved in mitochondrial biosynthesis, and (iii) discovery of specific mitochondrial DNA. Many mitochondrial diseases are accompanied by mutations in this DNA. Inheritance is by maternal transmission. The metabolic defects encompass the electron transport complexes, intermediates of the tricarboxylic acid cycle, and substrate transport. The clinical manifestations are protean, most often involving skeletal muscle and the central nervous system. In addition to being a primary cause of disease, mitochondrial DNA mutations and impaired oxidation have now been found to occur as secondary phenomena in aging as well as in age-related degenerative diseases such as Parkinson, Alzheimer, and Huntington diseases, amyotrophic lateral sclerosis and cardiomyopathies, atherosclerosis, and diabetes mellitus. Manifestations of both the primary and secondary mitochondrial diseases are thought to result from the production of oxygen free radicals. With increased understanding of the mechanisms underlying the mitochondrial dysfunctions has come the beginnings of therapeutic strategies, based mostly on the administration of antioxidants, replacement of cofactors, and provision of nutrients. At the present accelerating pace of development of what may be called mitochondrial medicine, much more is likely to be achieved within the next few years.

Published
1994
Full Text
View/download PDF

188. [Physiopathology of mitochondria. From Luft's disease to aging and diabetes].

Author

Luft R and Luthman H

Subjects
DNA genetics, Diabetes Mellitus, Type 2 metabolism, Diabetes Mellitus, Type 2 pathology, Humans, Mitochondria, Muscle metabolism, Mitochondria, Muscle ultrastructure, Muscular Diseases metabolism, Muscular Diseases pathology, Syndrome, Aging physiology, Diabetes Mellitus, Type 2 physiopathology, Mitochondria, Muscle physiology, Muscular Diseases physiopathology
Abstract

The first disease due to disturbances in a cell organelle was discovered in 1959-62, and its basis was loose-coupling of oxidative phosphorylation in the skeletal muscle mitochondria accompanied by severe alterations of their structure (Luft's disease). During the 1980s, functional disturbances and structural alterations in the mitochondria were observed in more than 100 disease entities, mainly in parts of the central nervous system and skeletal muscles. A second breakthrough in this area was the discovery in 1963-64 that mitochondria had their own DNA, mtDNA. Following the observation in 1988 of mutations of mtDNA in mitochondrial diseases, such mutations--mainly deletions and point mutations--were observed in almost all mitochondrial diseases. A remarkable extension of the area is the notion that "normal" ageing is accompanied by decreased oxidative phosphorylation and the appearance of mtDNA mutations. During the last two years, such changes have been demonstrated in diseased states in tissues and organs, which are especially reliant on oxygen supply: in the central nervous system (Parkinson's disease, some types of epilepsy and seizures, Huntington's disease, possibly also in Alzheimer's disease); in heart muscle (cardiomyopathies) and in skeletal muscle. Type 2 diabetes or NIDDM engages two tissues most reliant on oxygen consumption, the pancreatic islets (insulin secretion) and skeletal muscle (insulin sensitivity). Both these functions are genetically determined, the latter to a high degree also controlled by "environmental" factors. The evident age factor in the development of NIDDM could be on a par with the "normal" ageing process.(ABSTRACT TRUNCATED AT 250 WORDS)

Published
1993

190. DNA polymorphisms in the human tyrosine hydroxylase/insulin/insulin-like growth factor II chromosomal region in relation to glucose and insulin responses.

Author

Sten-Linder M, Wedell A, Iselius L, Efendic S, Luft R, and Luthman H

Subjects
Alleles, Base Sequence, Chromosome Mapping, DNA Restriction Enzymes, Deoxyribonucleases, Type II Site-Specific, Diabetes Mellitus, Type 2 blood, Diabetes Mellitus, Type 2 enzymology, Female, Genotype, Haplotypes, Humans, Insulin blood, Male, Middle Aged, Molecular Sequence Data, Oligodeoxyribonucleotides, Reference Values, Restriction Mapping, Blood Glucose metabolism, Chromosomes, Human, Pair 11, Diabetes Mellitus, Type 2 genetics, Insulin genetics, Insulin-Like Growth Factor II genetics, Polymorphism, Restriction Fragment Length, Tyrosine 3-Monooxygenase genetics
Abstract

The feasibility of disease association studies using polymorphic DNA markers in the tyrosine hydroxylase/insulin/insulin-like growth factor II chromosomal region was indicated by a high degree of linkage disequilibrium found in haplotypes. Haplotypes were resolved in the parents from Scandinavian nuclear families by studying the segregation of eight DNA polymorphisms. Comparison of observed vs expected frequencies of haplotypes, as well as pairwise measures of linkage disequilibrium, indicated a high degree of linkage disequilibrium. Five restriction fragment length polymorphisms linked to the tyrosine hydroxylase/insulin/insulin growth factor II region of chromosome 11 were investigated in relation to Type 2 (non-insulin-dependent) diabetes mellitus, and to glucose and insulin responses to glucose infusion in healthy subjects. No significant differences in genotype frequencies between Type 2 diabetic (n = 53) and healthy subjects (n = 106) were found. A significant association (p < 0.001) was initially found between genotypes defined by a PstI polymorphism located 5' of the tyrosine hydroxylase gene and the early glucose response to a standardized glucose infusion test in healthy subjects. However, a follow-up study of 112 healthy individuals failed to confirm this finding.

Published
1993
Full Text
View/download PDF

194. Screening for insulin receptor gene DNA polymorphisms associated with glucose intolerance in a Scandinavian population.

Author

Sten-Linder M, Vilhelmsdotter S, Wedell A, Stern I, Pollare T, Arner P, Efendić S, Luft R, and Luthman H

Subjects
Body Mass Index, DNA blood, DNA genetics, DNA isolation & purification, DNA Restriction Enzymes, Diabetes Mellitus, Type 2 physiopathology, Female, Genotype, Glucose Tolerance Test, Humans, Insulin blood, Leukocytes physiology, Male, Middle Aged, Phenotype, Reference Values, Sweden, Blood Glucose metabolism, Diabetes Mellitus, Type 2 genetics, Polymorphism, Restriction Fragment Length, Receptor, Insulin genetics
Abstract

The significance of insulin receptor gene variants in the aetiology of Type 2 (non-insulin-dependent) diabetes mellitus has been investigated by analysis of restriction fragment length polymorphisms in a genetically homogeneous Swedish population. Seven polymorphisms were analysed, spanning functionally important regions of the insulin receptor locus. Four of these polymorphisms were mapped more accurately within the gene compared to previous studies. The genotype distribution was compared in 76 Type 2 diabetic patients and 84 healthy control subjects. No significant differences were found in the distribution of genotypes between diabetic and control subjects at the p less than 0.01 level. In order to study the possible association between quantitative measures of glucose metabolism and these DNA polymorphisms, the fasting glucose and insulin concentrations were compared in the different genotype groups of control subjects and mildly diabetic patients treated with diet. No differences in fasting glucose or insulin concentrations were found at the p less than 0.005 level of significance. In conclusion, no significant associations were found between insulin receptor gene DNA polymorphisms and glucose intolerance.

Published
1991
Full Text
View/download PDF

199. Peritoneo-venous shunting for ascites.

Author

Leveen HH, Christoudias G, Ip M, Luft R, Falk G, and Grosberg S

Subjects
Animals, Ascites etiology, Ascites urine, Breathing Exercises, Dogs, Hematocrit, Humans, Liver Cirrhosis, Biliary complications, Methods, Pressure, Prosthesis Design, Venous Pressure, Ascites surgery
Abstract

A new minor surgical procedure for ascites has been devised wherein a specially designated one way pressure activated valve is implanted to create a permanent peritoneo-venous shunt. The normally closed valves opens only when the peritoneal pressure rises 3-5 cm higher than the intrathoracic venous pressure thus preventing backflow of blood and closing the valve should the venous pressure rise from the over-infusion of ascitic fluid. The procedure has been performed on 45 patients but nine were terminal at the time of surgery. Prolonged relief of ascites occurred in 28 of 37 cases.

Published
1974
Full Text
View/download PDF

200. Somatostatin and insulin secretion.

Author

Efendic S, Lins PE, and Luft R

Subjects
3',5'-Cyclic-AMP Phosphodiesterases metabolism, Animals, Cyclic AMP metabolism, Glucose metabolism, Glucose pharmacology, Humans, Insulin Secretion, Islets of Langerhans enzymology, Pancreas drug effects, Pancreas metabolism, Rats, Somatostatin administration & dosage, Somatostatin analogs & derivatives, Insulin metabolism, Somatostatin pharmacology
Published
1978
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results