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521 results on '"Liu, Mingbo"'

159. A LiF(200) double‐curved crystal for performance improvement of a monochromatic X‐ray fluorescence source.

Author

Cheng, Dawei, Liu, Mingbo, Ni, Ziyue, Shen, Xuejing, and Jia, Yunhai

Subjects
*LITHIUM fluoride, *SPECTRAL lines, *CRYSTALS, *ATOMIC number, *LIGHT elements, *X-ray fluorescence
Abstract

LiF(200) diffraction crystals are commonly used in high‐power wavelength‐dispersive X‐ray fluorescence (XRF) but seldom in benchtop energy‐dispersive XRF instruments because of their low diffraction efficiencies. We herein describe a method of producing a double‐curved crystal (DCC) from an LiF(200) plate crystal, wherein diverging X‐rays onto the DCC can be totally diffracted and focused. This improves the performance of a monochromatic wavelength X‐ray fluorescence (MWXRF) source. The characteristic 5.415 keV line of a chromium target was diffracted by an LiF(200) DCC; this MWXRF was used to detect weak signals of trace light elements with atomic numbers 11–22 because of the extremely low and continuous background spectrum. The MWXRF intensity approached 5.3 × 108 cps, and it exhibited excellent focusing with a 0.24 × 0.52 mm focal spot. Trace‐ and high‐concentration levels were calibrated respectively to ensure good accuracy. The lower limits of detection of sulfur and chlorine in oils were 1.75 and 0.63 μg/g, respectively. The MWXRF source could be developed into an integrated device including a mini‐focus X‐ray tube and an LiF(200) DCC. Designing the DCC to diffract characteristic MWXRF would provide a system of practical applicability, especially for some serious overlapping and interferential spectral lines. [ABSTRACT FROM AUTHOR]

Published
2021
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160. Research on Physical Layer Conformance Testing Technology of Ethernet Interface

Author

Qianhong Zhao, Yang Yang, Liu Mingbo, Sun Wenjie, and Lu Han

Subjects
Ethernet, Transmission (telecommunications), business.industry, Computer science, Embedded system, Physical layer, Test method, Network interface, Conformance testing, business, Networking hardware, Test data
Abstract

The Ethernet physical layer is located at the bottom of the network structure and is responsible for the transmission and reception of electrical signals. The performance of the physical layer will directly affect the communication quality of network devices. According to the requirements of the IEEE 802.3-2000 and ANSI X3.263-1995 standards for the physical layer of the Ethernet, the physical layer conformance test standards and requirements of the 100Base-TX and 1000Base-T network interfaces are studied, and the physical layer is designed consistently. The test method shows that the test data is accurate and the test method can meet the requirements related to the physical layer conformance test.

Published
2020

181. H19/miR‐107/HMGB1 axis sensitizes laryngeal squamous cell carcinoma to cisplatin by suppressing autophagy in vitro and in vivo.

Author

Chen, Liwei, Xu, Zhijian, Zhao, Jiandong, Zhai, Xingyou, Li, Jianhui, Zhang, Yongxia, Zong, Liang, Peng, Honghua, Qi, Jixia, Kong, Xinru, Fang, Zhongju, and Liu, Mingbo

Subjects
SQUAMOUS cell carcinoma, LINCRNA, AUTOPHAGY, DRUG resistance
Abstract

Laryngeal squamous cell carcinoma (LSCC) is the most common malignant tumor, which occurs in the head and neck. Current treatments for LSCC are all largely weakened by increasing drug resistance. Our study aimed to investigate the effects of long noncoding RNA (lncRNA) H19 on drug resistance in LSCC. In our study, we found that the level of H19 was sharply upregulated in LSCC tissues and drug‐resistant cells compared with the control. Besides, the expression of high‐mobility group B1 (HMGB1) was elevated, and microRNA107 (miR‐107) was suppressed in drug‐resistant cells compared with the control. Further study revealed that the interference of H19 by short hairpin RNA (shRNA) effectively suppressed high autophagy level and obvious drug resistance in drug‐resistant cells. Besides that, miR‐107 was predicted as a target of H19 and inhibiting effects of H19 shRNA on autophagy and drug resistance were both reversed by miR‐107 inhibitor. Moreover, HMGB1 was predicted as a target of miR‐107 in LSCC cells and knockdown of HMGB1 was able to suppress autophagy and drug resistance in LSCC cells. In addition, our investigation demonstrated that H19 shRNA exerted an inhibiting effect on autophagy and drug resistance by downregulating HMGB1 by targeting miR‐107. Finally, the in vivo experiment revealed that LV‐H19 shRNA strongly suppressed drug resistance compared with the usage of cisplatin individually. Taken together, our research indicated an H19–miR‐107–HMGB1 axis in regulating the autophagy‐induced drug resistance in LSCC in vitro and in vivo, providing novel targets for molecular‐targeted therapy and broadening the research for LSCC. [ABSTRACT FROM AUTHOR]

Published
2021
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200. Design and implementation of IP network traffic monitoring system

Author

Liu Mingbo, Zhao Qianhong, Sun Wenjie, and Tian Zhaoping

Subjects
Network administrator, Protocol data unit, Network packet, business.industry, Computer science, computer.internet_protocol, Network security, Packet processing, Data flow diagram, Internet protocol suite, Business analysis, business, computer, Computer network
Abstract

Network packet capture and analysis technology is a cornerstone of network security and protocol analysis technology. On the analysis of the LAN IP network traffic monitoring requirements, this paper detailed introduces the design ideas of traffic monitoring system based on WinPcap technology, expounds the key technologies and features in the process of system implementation, focusing on huge amounts of packet processing technology, task dependent protocol data analysis technology, and behavior decision technology based on the strategy. Tests show that the system can realize IP data flow quickly and accurately capturing and business analysis, and determining whether the business is legally and effective according to the network administrator predefined behavior strategy, and gives tips with intuitive and friendly information. The system meets the actual needs.

Published
2016

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