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Key Points Question How do oncologists successfully navigate and miss opportunities for discussions about end of life (EOL), including advance care planning, palliative care, discontinuation of disease-directed treatment, hospice care, and after-death wishes, with outpatients with advanced cancer? Findings In this secondary qualitative analysis of 423 outpatient encounters, only 21 encounters (5%) included EOL discussions, whereas a random sample of 93 encounters revealed that 35 encounters (38%) included missed opportunities for EOL discussions. Oncologists missed opportunities for these discussions when they responded inadequately to patient concerns about disease progression or dying, used optimistic future talk to address patient concerns, or expressed concern over treatment discontinuation. Meaning Opportunities for EOL discussions were rarely realized, and missed opportunities for these discussions were common, a trend that seemed to mirror oncologists’ treatment style., This qualitative study describes successful navigation and missed opportunities for end-of-life discussions, including advance care planning, palliative care, discontinuation of disease-directed treatment, hospice care, and after-death wishes, between oncologists and outpatients with advanced cancer., Importance Early discussion of end-of-life (EOL) care preferences improves clinical outcomes and goal-concordant care. However, most EOL discussions occur approximately 1 month before death, despite most patients desiring information earlier. Objective To describe successful navigation and missed opportunities for EOL discussions (eg, advance care planning, palliative care, discontinuation of disease-directed treatment, hospice care, and after-death wishes) between oncologists and outpatients with advanced cancer. Design, Setting, and Participants This study is a secondary qualitative analysis of outpatient visits audio-recorded between November 2010 and September 2014 for the Studying Communication in Oncologist-Patient Encounters randomized clinical trial. The study was conducted at 2 US academic medical centers. Participants included medical, gynecological, and radiation oncologists and patients with stage IV malignant neoplasm, whom oncologists characterized as being ones whom they “…would not be surprised if they were admitted to an intensive care unit or died within one year.” Data were analyzed between January 2018 and August 2020. Exposures The parent study randomized participants to oncologist- and patient-directed interventions to facilitate discussion of emotions. Encounters were sampled across preintervention and postintervention periods and all 4 treatment conditions. Main Outcomes and Measures Secondary qualitative analysis was done of patient-oncologist dyads with 3 consecutive visits for EOL discussions, and a random sample of 7 to 8 dyads from 4 trial groups was analyzed for missed opportunities. Results The full sample included 141 patients (54 women [38.3%]) and 39 oncologists (8 women [19.5%]) (mean [SD] age for both patients and oncologists, 56.3 [10.0] years). Of 423 encounters, only 21 (5%) included EOL discussions. Oncologists reevaluated treatment options in response to patients’ concerns, honored patients as experts on their goals, or used anticipatory guidance to frame treatment reevaluation. In the random sample of 31 dyads and 93 encounters, 35 (38%) included at least 1 missed opportunity. Oncologists responded inadequately to patient concerns over disease progression or dying, used optimistic future talk to address patient concerns, or expressed concern over treatment discontinuation. Only 4 of 23 oncologists (17.4%) had both an EOL discussion and a missed opportunity. Conclusions and Relevance Opportunities for EOL discussions were rarely realized, whereas missed opportunities were more common, a trend that mirrored oncologists’ treatment style. There remains a need to address oncologists’ sensitivity to EOL discussions, to avoid unnecessary EOL treatment.

This thesis presents results of computations of supersonic flow over finite cylinders with varying geometries at the cylinder-wall juncture. The flow domain and geometries were modeled after experiments conducted at University of Tennessee Space Institute (UTSI). CREATE Kestrel (KCFD) was used to perform improved-delayed detached simulations (IDDES) of the unsteady flow. Time-accurate data were collected via taps along the centerline partially on the surface of the cylinder geometries and on the wall upstream of the cylinder. Spectra of the pressure signals and two-point correlations were computed to compare the flow between the different cases consisting of a baseline cylinder, the cylinder with a smaller gap, and the cylinder with a wider fairing. Properties on the cylinder surface for the gap case had the greatest difference compared to the others. In addition, the spectral content showed higher frequency activity for the gap case on the surface in front of the cylinder.