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Objective: To evaluate the feasibility and safety of marking targeting biopsy (MTB) in the intraoperative localization value of colon polypectomy. Methods: The clinical data from patients with polyp of colon discovered under colonoscopy from January 2014 to January 2016 were retrospectively analyzed. A total of 87 patients conformed to the inclusion criteria, among them, 43 received colonoscopic polypectomy one week after MTB (MTB group), while 44 underwent colonoscopic polypectomy one week after conventional biopsy (conventional group). The time consumption in colonoscopic treatment, polypectomy rate and postoperative complications between two groups were compared. Results: The time consumed in operation in the MTB group was 25.5 (±8.6) minutes, while that in conventional group was 42.0 (±20.5) minutes, and the difference was statistically significant (P0.05). Conclusions: The localization value of MTB in colon polypectomy is definitely feasible, safe and effective, which can greatly shorten the time of endoscopic colon polypectomy, mitigate patient sufferings, and reduce the incidence of false negative rate of polyp. It displays favorable clinical application value and is worthy of being promoted in clinic. doi: https://doi.org/10.12669/pjms.36.2.756 How to cite this:Song LY, Lin Q, Li LB, Cheng X. Clinical exploration of marking targeting biopsy in the intraoperative localization value of colon polypectomy. Pak J Med Sci. 2020;36(2):100-104. doi: https://doi.org/10.12669/pjms.36.2.756 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

The novel ligand N,N,N′′′′,N′′′′-tetrabutyl-N′′′,N′′′-(N″,N″-diethyl)-ethidene bisdiglycolamide (TBEE-BisDGA) and other eight analogous extractants have been synthesized and characterized by NMR and HRMS. The solvent extraction of Th4+, UO2 2+ and Eu3+ from nitric acid solution using the above BisDGA extractants was investigated in 1-dodecanol at 30 ± 1 °C. The extractants exhibited higher affinity toward Th4+ than UO2 2+ and Eu3+ in the present system. The maximum value of separation factor SF Th(IV)/U(VI) and SF Th(IV)/Eu(III) is 78.5 and 53.3 respectively for TBEE-BisDGA, 88.1 and 69.5 respectively in the case of TB i-PE-BisDGA at 3 M HNO3 solution.

Traditional theories and methods for comprehensive environmental performance evaluation are challenged by the appearance of big data because of its large quantity, high velocity, and high diversity, even though big data is defective in accuracy and stability. In this paper, we first review the literature on environmental performance evaluation, including evaluation theories, the methods of data envelopment analysis, and the technologies and applications of life cycle assessment and the ecological footprint. Then, we present the theories and technologies regarding big data and the opportunities and applications for these in related areas, followed by a discussion on problems and challenges. The latest advances in environmental management based on big data technologies are summarized. Finally, conclusions are put forward that the feasibility, reliability, and stability of existing theories and methodologies should be thoroughly validated before they can be successfully applied to evaluate environmental performance in practice and provide scientific basis and guidance to formulate environmental protection policies.

Fractional quantum Hall (FQH) system at Landau level filling fraction $��=5/2$ has long been suggested to be non-Abelian, either Pfaffian (Pf) or antiPfaffian (APf) states by numerical studies, both with quantized Hall conductance $��_{xy}=5e^2/2h$. Thermal Hall conductances of the Pf and APf states are quantized at $��_{xy}=7/2$ and $��_{xy}=3/2$ respectively in a proper unit. However, a recent experiment shows the thermal Hall conductance of $��=5/2$ FQH state is $��_{xy}=5/2$. It has been speculated that the system contains random Pf and APf domains driven by disorders, and the neutral chiral Majorana modes on the domain walls may undergo a percolation transition to a $��_{xy}=5/2$ phase. In this work, we do perturbative and non-perturbative analyses on the domain walls between Pf and APf. We show the domain wall theory possesses an emergent SO(4) symmetry at energy scales below a threshold $��_1$, which is lowered to an emergent U(1)$\times$U(1) symmetry at energy scales between $��_1$ and a higher value $��_2$, and is finally lowered to the composite fermion parity symmetry $\mathbb{Z}_2^F$ above $��_2$. Based on the emergent symmetries, we propose a phase diagram of the disordered $��=5/2$ FQH system, and show that a $��_{xy}=5/2$ phase arises at disorder energy scales $��>��_1$. Furthermore, we show the gapped double-semion sector of $N_D$ compact domain walls contributes non-local topological degeneracy $2^{N_D-1}$, causing a low-temperature peak in the heat capacity. We implement a non-perturbative method to bootstrap generic topological 1+1D domain walls (2-surface defects) applicable to any 2+1D non-Abelian topological order. We identify potentially relevant spin TQFTs for various $��= 5/2$ FQH states in terms of fermionic version of U(1)$_{\pm 8}$ Chern-Simons theory $\times \mathbb{Z}_8$-class TQFTs., 44 pages, 9 figures, 3 tables. v2: Clarification/Refs added

A new palladium-catalyzed three-component coupling involving acylation/alkenylation of aryl iodide is reported. The reaction was carried out with readily available starting materials and gave the ortho-acylated styrene in moderate to good yields. Compared with previous Catellani–Lautens reactions, this reaction is the first example of introducing an acyl group at the ortho position of aryl iodides. The proposed PdIV complex, generated via oxidative addition of the carboxylic anhydrides, is a key intermediate for this transformation.

A photocatalyst (AC@TiO2-S) based on active carbon (AC) as a support and TiO2 as active sites has been successfully prepared through a facile, controlled sol–gel approach and characterized by Fourier transform infrared (FT-IR) spectroscopy, X-ray photoelectron spectroscopy (XPS), X-ray powder diffraction (XRD), nitrogen adsorption analysis, transmission electron microscopy (TEM) and scanning electron microscopy (SEM). Importantly, the as prepared AC@TiO2-S exhibits much higher photocatalytic activity than the catalyst AC@TiO2-G (prepared by sol–gel approach) for the degradation of methyl orange (MO) under visible light irradiation (λ > 420 nm). Additionally, this supported catalyst can be easily separated from the reaction system and reused for up to five cycles without significant loss in activity, indicating its excellent recyclability. On the basis of the results, AC@TiO2-S is promising for application in the degradation of other dyes, and the controllable sol–gel method can be applied in other fields.

Without extra addition of sulfinate salt, allylic sulfones were synthesized by palladium-catalyzed cross-coupling of aryl iodide with N-tosylhydrazone. In this transformation, not only the diazo compound but also the sulfinate salt, which were both generated in situ from base-mediated decomposition of the N-tosylhydrazone, was used as nucleophilic partner.

A versatile, convenient, and environmentally friendly protocol for the synthesis of substituted tetrahydroquinolines is presented (21 examples).

A direct nitration of aromatic sulfonamides using sodium nitrite as the nitrating agent has been developed. The reaction shows typically mono-substitution selectivity and can be enlarged to the gram scale with good yield.

The electrophilic cyclization of various propargylic oxirane compounds and I2 offers an efficient and straightforward route to highly substituted iodofurans under mild reaction conditions. Further functionalization has demonstrated that the iodo derivatives obtained are potential synthetic intermediates for the amplification of molecular complexity. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)

A simple strategy for the synthesis of highly substituted 2-imidazolines starting from terminal alkynes, sulfonyl azides, and N-unsubstituted aziridines via two steps with high regioselectivity is described.

The reaction of cyclohexyl isocyanide with various aldehydes and 1,3-dicarbonyl compounds catalyzed by piperidine is described. The protocol offers facile and efficient synthesis of 5-hydroxy-2H-pyrrol-2-one derivatives from readily available starting materials in high yields.

A general process for the efficient synthesis of vinyl sulfones has been developed using commercially available sulfinic acid sodium salts and dibromides. A variety of phenyl and methyl vinyl sulfones have been formed in good yields, in the absence of any catalyst.

This efficient, convenient, and direct nitration protocol tolerates a wide range of functional groups and shows typically mono-substitution selectivity.

In a kagome lattice, the time reversal symmetry can be broken by a staggered magnetic flux emerging from ferromagnetic ordering and intrinsic spin-orbit coupling, leading to several wellseparated nontrivial Chern bands and intrinsic quantum anomalous Hall effect. Based on this idea and ab initio calculations, we propose the realization of the intrinsic quantum anomalous Hall effect in the single layer Cs2Mn3F12 kagome lattice and on the (001) surface of a Cs2LiMn3F12 single crystal by modifying the carrier coverage on it, where the band gap is around 20 meV. Moreover, a simplified tight binding model based on the in-plane dd\sigma antibonding states is constructed to understand the topological band structures of the system.