Search

Your search keyword '"Lee, Tai"' showing total 2,747 results
Start Over Author "Lee, Tai"
2,747 results on '"Lee, Tai"'

158. Characterization of the pleural microenvironment niche and cancer transition using single-cell RNA sequencing in EGFR-mutated lung cancer

Author

Wu, Yu-Yuan, primary, Hsu, Ya-Ling, additional, Huang, Yung-Chi, additional, Su, Yue-Chiu, additional, Wu, Kuan-Li, additional, Chang, Chao-Yuan, additional, Ong, Chai-Tung, additional, Lai, Jia-Chen, additional, Shen, Tzu-Yen, additional, Lee, Tai-Huang, additional, Hung, Jen-Yu, additional, and Tsai, Ying-Ming, additional

Published
2023
Full Text
View/download PDF

165. The CanPain SCI clinical practice guidelines for rehabilitation management of neuropathic pain after spinal cord injury: 2021 update

Author

Eldon Loh, Magdalena Mirkowski, Alexandria Roa Agudelo, David J. Allison, Brooke Benton, Thomas N. Bryce, Sara Guilcher, Tara Jeji, Anna Kras-Dupuis, Denise Kreutzwiser, Oda Lanizi, Gary Lee-Tai-Fuy, James W. Middleton, Dwight E. Moulin, Colleen O’Connell, Steve Orenczuk, Patrick Potter, Christine Short, Robert Teasell, Andrea Townson, Eva Widerström-Noga, Dalton L. Wolfe, Nancy Xia, and Swati Mehta

Subjects
Canada, Consensus, Neurology, Humans, Neuralgia, Neurology (clinical), General Medicine, Spinal Cord Injuries
Abstract

Study designClinical practice guidelines.ObjectivesThe objective was to update the 2016 version of the Canadian clinical practice guidelines for the management of neuropathic pain in people with spinal cord injury (SCI).SettingThe guidelines are relevant for inpatient, outpatient and community SCI rehabilitation settings in Canada.MethodsThe guidelines were updated in accordance with the Appraisal of Guidelines for Research and Evaluation II tool. A Steering Committee and Working Group reviewed the relevant evidence on neuropathic pain management (encompassing screening and diagnosis, treatment and models of care) after SCI. The quality of evidence was scored using Grading of Recommendations Assessment, Development and Evaluation (GRADE). A consensus process was followed to achieve agreement on recommendations and clinical considerations.ResultsThe working group identified and reviewed 46 additional relevant articles published since the last version of the guidelines. The panel agreed on 3 new screening and diagnosis recommendations and 8 new treatment recommendations. Two key changes to these treatment recommendations included the introduction of general treatment principles and a new treatment recommendation classification system. No new recommendations to model of care were made.ConclusionsThe CanPainSCI recommendations for the management of neuropathic pain after SCI should be used to inform practice.

Published
2022

166. Different Tyrosine Kinase Inhibitors Used in Treating EGFR-Mutant Pulmonary Adenocarcinoma with Brain Metastasis and Intracranial Intervention Have No Impact on Clinical Outcomes

Author

Kuo, Chia-Yu, primary, Tsai, Ming-Ju, additional, Hung, Jen-Yu, additional, Wu, Kuan-Li, additional, Tsai, Ying-Ming, additional, Tsai, Yu-Chen, additional, Chuang, Cheng-Hao, additional, Lee, Tai-Huang, additional, Chen, Huang-Chi, additional, Yang, Chih-Jen, additional, and Chong, Inn-Wen, additional

Published
2022
Full Text
View/download PDF

173. A calcium imaging large dataset reveals novel functional organization in macaque V4

Author

Wang, Tianye, Yao, Haoxuan, Lee, Tai Sing, Hong, Jiayi, Li, Yang, Jiang, Hongfei, Andolina, Ian Max, and Tang, Shiming

Subjects
FOS: Computer and information sciences, Computer Vision and Pattern Recognition (cs.CV), FOS: Biological sciences, Neurons and Cognition (q-bio.NC)
Abstract

The topological organization and feature preferences of primate visual area V4 have been primarily studied using artificial stimuli. Here, we combined large-scale calcium imaging with deep learning methods to characterize and understand how V4 processes natural images. By fitting a deep learning model to an unprecedentedly large dataset of columnar scale cortical responses to tens of thousands of natural stimuli and using the model to identify the images preferred by each cortical pixel, we obtained a detailed V4 topographical map of natural stimulus preference. The map contains distinct functional domains preferring a variety of natural image features, ranging from surface-related features such as color and texture to shape-related features such as edge, curvature, and facial features. These predicted domains were verified by additional widefield calcium imaging and single-cell resolution two-photon imaging. Our study reveals the systematic topological organization of V4 for encoding image features in natural scenes., 36 pages, 17 figures

Published
2023
Full Text
View/download PDF

176. Learning Discriminative Sufficient Statistics Score Space for Classification

Author

Li, Xiong, Wang, Bin, Liu, Yuncai, Lee, Tai Sing, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Goebel, Randy, editor, Siekmann, Jörg, editor, Wahlster, Wolfgang, editor, Blockeel, Hendrik, editor, Kersting, Kristian, editor, Nijssen, Siegfried, editor, and Železný, Filip, editor

Published
2013
Full Text
View/download PDF

178. Risk of Hepatitis B Virus (HBV) Reactivation in HBsAg-Negative, Anti-HBc-Negative Patients Receiving Rituximab for Autoimmune Diseases in HBV Endemic Areas

Author

Lan, Ting-Yuan, primary, Lin, Yen-Chun, additional, Tseng, Tai-Chung, additional, Yang, Hung-Chih, additional, Kao, Jui-Hung, additional, Cheng, Chiao-Feng, additional, Lee, Tai-Ju, additional, Huang, Shang-Chin, additional, Lu, Cheng-Hsun, additional, Li, Ko-Jen, additional, and Hsieh, Song-Chou, additional

Published
2022
Full Text
View/download PDF

192. C

Author

Davis, Justin R., Giles, Andrew C., Rankin, Catharine H., Bell, Jonathan, Kimura, Hiroshi, Uemura, Tadashi, Kidokoro, Yoshi, Lemieux, Mado, Koninck, Paul De, Carbone, Emilio, Senatore, Adriano, Spafford, J. David, Dowie, Megan J., Grimsey, Natasha L., Glass, Michelle, Gillis, Kevin D., Hunter, Peter, Budgell, Brian, Roy, Arijit, Wilson, Richard J. A., Hikosaka, Okihide, Esfeld, Michael, Harbecke, Jens, Mitsuhashi, Takayuki, Takahashi, Takao, Kageyama, Ryoichiro, Ohsawa, Ryosuke, Ohtsuka, Toshiyuki, Lalley, Peter M., Nitabach, Michael N., Paton, Julian F. R., Waitzman, David M., Nattie, Eugene, Li, Aihua, Tsunoda, Ikuo, Kobayashi-Warren, Mikako, Libbey, Jane E., Fujinami, Robert S., Kulkarni, Amod P., Kellaway, Laurie A., Kotwal, Girish J., Morgen, Katrin E., Ciufolini, Maria Grazia, Nicoletti, Loredana, Davis, Randall L., Hofer, Markus J., Campbell, Iain L., Jensen, Troels S., Finnerup, Nanna B., Straub, Volko A., Benarroch, Eduardo E., Bronstein, Adolfo M., Nissant, Antoine, Bloedel, James R., Bracha, Vlastislav, Highstein, Stephen M., Scudder, Charles A., Kachur, Torah M., Pilgrim, Dave B., André, Holley, Mindell, Joseph A., Maduke, Merritt, Ormond, John, Woodin, Melanie A., Datta, Subimal, Eisenstat, David D., Severinsen, Kaare, Jakobsen, Johannes, Merrow, Martha, Roenneberg, Till, Schall, Jeffrey D., Vogt, Brent A., Morecraft, Robert J., Tischkau, Shelley, Gerkema, Menno P., Buijs, Ruud M., Lewy, Alfred J., Hazlerigg, David, Yamamoto, Takashi, Epstein, Marcelo, Ripperger, Jürgen A., Albrecht, Urs, Kramer, Achim, Ruggero, Mario A., Shannon, Robert V., Malmierca, Manuel S., Smith, Philip H., Sodian, Beate, Nieder, Andreas, Mast, Fred W., Godde, Ben, Hansen, Thorsten, Gegenfurtner, Karl R., Faure, Philippe, Allan, Douglas W., Asoh, Hideki, Jänig, Wilfrid, Rybak, Ilya A., Smith, Jeffrey C., Karniel, Amir, Sanguineti, Vittorio, Mansergh, Fiona, R.Wolpaw, Jonathan, McFarland, Dennis J., Mareschal, Denis, Althaus, Nadja, Lee, Tai Sing, Cleland, Thomas A., Goodwin, Graham C., Feuer, Arie, Latash, Mark L., Marín, Oscar, Lucassen, Paul J., Boekhoorn, Karin, Francis, Fiona, Groenewegen, Henk J., Ogawa, Hisashi, Macefield, Vaughan G, Birznieks, Ingvars, Biel, Martin, Binder, Marc D., editor, Hirokawa, Nobutaka, editor, and Windhorst, Uwe, editor

Published
2009
Full Text
View/download PDF

193. A fast and high-quality charge model for the next generation general AMBER force field.

Author

He, Xibing, Man, Viet H., Yang, Wei, Lee, Tai-Sung, and Wang, Junmei

Subjects
COMPUTER-assisted drug design, ATOMIC charges, PERMITTIVITY, QUANTUM mechanics, ELECTRIC potential, SOLUBILITY, DRUG design
Abstract

The General AMBER Force Field (GAFF) has been broadly used by researchers all over the world to perform in silico simulations and modelings on diverse scientific topics, especially in the field of computer-aided drug design whose primary task is to accurately predict the affinity and selectivity of receptor–ligand binding. The atomic partial charges in GAFF and the second generation of GAFF (GAFF2) were originally developed with the quantum mechanics derived restrained electrostatic potential charge, but in practice, users usually adopt an efficient charge method, Austin Model 1-bond charge corrections (AM1-BCC), based on which, without expensive ab initio calculations, the atomic charges could be efficiently and conveniently obtained with the ANTECHAMBER module implemented in the AMBER software package. In this work, we developed a new set of BCC parameters specifically for GAFF2 using 442 neutral organic solutes covering diverse functional groups in aqueous solution. Compared to the original BCC parameter set, the new parameter set significantly reduced the mean unsigned error (MUE) of hydration free energies from 1.03 kcal/mol to 0.37 kcal/mol. More excitingly, this new AM1-BCC model also showed excellent performance in the solvation free energy (SFE) calculation on diverse solutes in various organic solvents across a range of different dielectric constants. In this large-scale test with totally 895 neutral organic solvent–solute systems, the new parameter set led to accurate SFE predictions with the MUE and the root-mean-square-error of 0.51 kcal/mol and 0.65 kcal/mol, respectively. This newly developed charge model, ABCG2, paved a promising path for the next generation GAFF development. [ABSTRACT FROM AUTHOR]

Published
2020
Full Text
View/download PDF

195. Review of Research on Educational Leadership and Management in Hong Kong, 1995-2012: Topographical Analysis of an Emergent Knowledge Base

Author

Hallinger, Philip, Lee, Tai Hoi Theodor, and Szeto, Elson

Abstract

A recent study of scholarship on educational leadership and management in East Asia identified a rapidly growing corpus of published studies focusing on educational leadership and management in Hong Kong. This article undertakes a "topographical analysis" of this literature with the aim of describing the nature of topics and research methods employed over the past decade. The authors analyze the body of articles published in a "core" set of eight educational leadership and management journals between 1995 and 2012. The descriptive study offers insights into the nature of this emergent literature from a single non-Western society.

Published
2013
Full Text
View/download PDF

198. An Application Service Provider (ASP) Based Project Management System

Author

Lee, Tai Sik, Kim, Young Hyun, Lee, Dong Wook, Swain, Saumya R, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Dough, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, and Luo, Yuhua, editor

Published
2006
Full Text
View/download PDF

199. Towards inclusive funding practices for early career researchers

Author

de Winde, Charlotte, Sarabipour, Sarvenaz, Carignano, Hugo, davla, sejal, eccles, david, Hainer, Sarah, haidar, mansour, Ilangovan, Vinodh, Jadavji, Nafisa, Kritsiligkou, Paraskevi, Lee, Tai-Ying, Ólafsdóttir, Freyja, and Symmons, Orsolya

Subjects
#research, #STEMM, #FairFunding, #ECR, #funding, #ResearchFunding
Abstract

Funding bodies have different practices in place to assess fellowship and grant proposals. Some of these are not beneficial for early career researchers (ECRs), and some are. In this initiative, we investigated which aspects of funding assessment can and should be improved, and emphasise how these good practices will lead to fair funding in general, and more specific for ECRs. Our aim is to create awareness amongst ECRs of good practices regarding fair funding, and to have a discussion with funding organizations, stakeholders and the scientific community as a whole to promote fair funding practices and drive policy changes.

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results