30,856 results on '"LEE, A. T."'
Search Results
152. Complement C3 knockout protects photoreceptors in the sodium iodate model
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Wang, Tan, Song, Ying, Bell, Brent A., Anderson, Brandon D., Lee, Timothy T., Yu, Weihong, and Dunaief, Joshua L.
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- 2025
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153. Romanticizing Decolonization and Asian Epistemology: Reflections on Identity and Space
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Lee, Jack T.
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Recent calls for the decolonization of the academy demand recognition for diverse canons of knowledge. Asia's economic ascent also imparts rising confidence among Asian scholars and institutions to promote indigenous knowledge. While these global calls for emancipation are invigorating, decolonial scholarship is prone to sterile theorization, historical fixity, and an overt romanticization of the Global South. Drawing on my lived experiences as an Asian academic, I reflect on decolonization and Asian epistemology from five different spaces in my life: (1) Northern Europe, (2) Toronto, (3) Southeast Asia, (4) Kazakhstan and (5) the United Kingdom. I analyze these spaces by using the concepts of intellectual captivity and decolonization from Syed Hussein Alatas and Kuan-Hsing Chen. Specifically, the tendency for decolonization movements to descend into nationalism, nativism, and civilizationalism provides provocative insights on epistemic justice (Chen, 2010). I demonstrate how epistemology as practice can reveal a colonial mindset even among academics who engage in social justice discourse and international work. I also highlight examples of indigenous knowledge that reinforce inequality based on race, gender, sexual orientation and religion. As more individuals with hybrid identities (race, culture, and nationality) enter academe and pursue careers that require international mobility, it is imperative that decolonization moves beyond reductive categories of identity that reproduce stereotypes. I conclude with reflections on the role of comparative and international education research in decolonization movements.
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- 2023
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154. A measurement of the mean central optical depth of galaxy clusters via the pairwise kinematic Sunyaev-Zel'dovich effect with SPT-3G and DES
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Schiappucci, E., Bianchini, F., Aguena, M., Archipley, M., Balkenhol, L., Bleem, L. E., Chaubal, P., Crawford, T. M., Grandis, S., Omori, Y., Reichardt, C. L., Rozo, E., Rykoff, E. S., To, C., Abbott, T. M. C., Ade, P. A. R., Alves, O., Anderson, A. J., Andrade-Oliveira, F., Annis, J., Avva, J. S., Bacon, D., Benabed, K., Bender, A. N., Benson, B. A., Bernstein, G. M., Bertin, E., Bocquet, S., Bouchet, F. R., Brooks, D., Burke, D. L., Carlstrom, J. E., Rosell, A. Carnero, Kind, M. Carrasco, Carretero, J., Cecil, T. W., Chang, C. L., Chichura, P. M., Chou, T. -L., Costanzi, M., Cukierman, A., da Costa, L. N., Daley, C., de Haan, T., Desai, S., Dibert, K. R., Diehl, H. T., Dobbs, M. A., Doel, P., Doux, C., Dutcher, D., Everett, S., Everett, W., Feng, C., Ferguson, K. R., Ferrero, I., Ferté, A., Flaugher, B., Foster, A., Frieman, J., Galli, S., Gambrel, A. E., García-Bellido, J., Gardner, R. W., Gatti, M., Giannantonio, T., Goeckner-Wald, N., Gruen, D., Gualtieri, R., Guns, S., Gutierrez, G., Halverson, N. W., Hinton, S. R., Hivon, E., Holder, G. P., Hollowood, D. L., Holzapfel, W. L., Honscheid, K., Hood, J. C., Huang, N., James, D. J., Knox, L., Korman, M., Kuehn, K., Kuo, C. -L., Lahav, O., Lee, A. T., Lidman, C., Lima, M., Lowitz, A. E., Lu, C., March, M., Mena-Fernández, J., Menanteau, F., Millea, M., Miquel, R., Mohr, J. J., Montgomery, J., Muir, J., Natoli, T., Noble, G. I., Novosad, V., Ogando, R. L. C., Padin, S., Pan, Z., Paz-Chinchón, F., Pereira, M. E. S., Pieres, A., Malagón, A. A. Plazas, Prabhu, K., Prat, J., Quan, W., Rahlin, A., Raveri, M., Rodriguez-Monroy, M., Romer, A. K., Rouble, M., Ruhl, J. E., Sanchez, E., Scarpine, V., Schubnell, M., Smecher, G., Smith, M., Soares-Santos, M., Sobrin, J. A., Suchyta, E., Suzuki, A., Tarle, G., Thomas, D., Thompson, K. L., Thorne, B., Tucker, C., Umilta, C., Vieira, J. D., Vincenzi, M., Wang, G., Weaverdyck, N., Weller, J., Whitehorn, N., Wu, W. L. K., Yefremenko, V., and Young, M. R.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We infer the mean optical depth of a sample of optically-selected galaxy clusters from the Dark Energy Survey (DES) via the pairwise kinematic Sunyaev-Zel'dovich (kSZ) effect. The pairwise kSZ signal between pairs of clusters drawn from the DES Year-3 cluster catalog is detected at $4.1 \sigma$ in cosmic microwave background (CMB) temperature maps from two years of observations with the SPT-3G camera on the South Pole Telescope. After cuts, there are 24,580 clusters in the $\sim 1,400$ deg$^2$ of the southern sky observed by both experiments. We infer the mean optical depth of the cluster sample with two techniques. The optical depth inferred from the pairwise kSZ signal is $\bar{\tau}_e = (2.97 \pm 0.73) \times 10^{-3}$, while that inferred from the thermal SZ signal is $\bar{\tau}_e = (2.51 \pm 0.55^{\text{stat}} \pm 0.15^{\rm syst}) \times 10^{-3}$. The two measures agree at $0.6 \sigma$. We perform a suite of systematic checks to test the robustness of the analysis.
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- 2022
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155. Uneven Extraction in Coffee Brewing
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Lee, W. T., Smith, A., and Arshad, A.
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Physics - Fluid Dynamics - Abstract
A recent experiment showed that, contrary to theoretical predictions, beyond a cutoff point grinding coffee more finely results in lower extraction. One potential explanation for this is that fine grinding promotes non-uniform extraction in the coffee bed. We investigate the possibility that this could occur due the interaction between dissolution and flow promoting uneven extraction. A low dimensional model in which there are two possible pathways for flow is derived and analysed. This model shows that, below a critical grind size, there is a decreasing extraction with decreasing grind size as is seen experimentally. In the model this is due to a complicated interplay between an initial imbalance in the porosities and permeabilities of the two pathways which is increased by flow and extraction, leading to the complete extraction of all soluble coffee from one pathway., Comment: 6 pages, 9 figures. Ancillary files: octave and wxMaxima code to derive and nondimensionalise model, solve it numerically and generate latex tables and figures. Accepted for publication in Physics of Fluids
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- 2022
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156. Joint analysis of DES Year 3 data and CMB lensing from SPT and Planck III: Combined cosmological constraints
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Abbott, T. M. C., Aguena, M., Alarcon, A., Alves, O., Amon, A., Andrade-Oliveira, F., Annis, J., Ansarinejad, B., Avila, S., Bacon, D., Baxter, E. J., Bechtol, K., Becker, M. R., Benson, B. A., Bernstein, G. M., Bertin, E., Blazek, J., Bleem, L. E., Bocquet, S., Brooks, D., Buckley-Geer, E., Burke, D. L., Camacho, H., Campos, A., Carlstrom, J. E., Rosell, A. Carnero, Kind, M. Carrasco, Carretero, J., Cawthon, R., Chang, C., Chang, C. L., Chen, R., Choi, A., Chown, R., Conselice, C., Cordero, J., Costanzi, M., Crawford, T., Crites, A. T., Crocce, M., da Costa, L. N., Davis, C., Davis, T. M., de Haan, T., De Vicente, J., DeRose, J., Desai, S., Diehl, H. T., Dobbs, M. A., Dodelson, S., Doel, P., Doux, C., Drlica-Wagner, A., Eckert, K., Eifler, T. F., Elsner, F., Elvin-Poole, J., Everett, S., Everett, W., Fang, X., Ferrero, I., Ferté, A., Flaugher, B., Fosalba, P., Friedrich, O., Frieman, J., García-Bellido, J., Gatti, M., George, E. M., Giannantonio, T., Giannini, G., Gruen, D., Gruendl, R. A., Gschwend, J., Gutierrez, G., Halverson, N. W., Harrison, I., Herner, K., Hinton, S. R., Holder, G. P., Hollowood, D. L., Holzapfel, W. L., Honscheid, K., Hrubes, J. D., Huang, H., Huff, E. M., Huterer, D., Jain, B., James, D. J., Jarvis, M., Jeltema, T., Kent, S., Knox, L., Kovacs, A., Krause, E., Kuehn, K., Kuropatkin, N., Lahav, O., Lee, A. T., Leget, P. -F., Lemos, P., Liddle, A. R., Lidman, C., Luong-Van, D., McMahon, J. J., MacCrann, N., March, M., Marshall, J. L., Martini, P., McCullough, J., Melchior, P., Menanteau, F., Meyer, S. S., Miquel, R., Mocanu, L., Mohr, J. J., Morgan, R., Muir, J., Myles, J., Natoli, T., Navarro-Alsina, A., Nichol, R. C., Omori, Y., Padin, S., Pandey, S., Park, Y., Paz-Chinchón, F., Pereira, M. E. S., Pieres, A., Malagón, A. A. Plazas, Porredon, A., Prat, J., Pryke, C., Raveri, M., Reichardt, C. L., Rollins, R. P., Romer, A. K., Roodman, A., Rosenfeld, R., Ross, A. J., Ruhl, J. E., Rykoff, E. S., Sánchez, C., Sanchez, E., Sanchez, J., Schaffer, K. K., Secco, L. F., Sevilla-Noarbe, I., Sheldon, E., Shin, T., Shirokoff, E., Smith, M., Staniszewski, Z., Stark, A. A., Suchyta, E., Swanson, M. E. C., Tarle, G., To, C., Troxel, M. A., Tutusaus, I., Varga, T. N., Vieira, J. D., Weaverdyck, N., Wechsler, R. H., Weller, J., Williamson, R., Wu, W. L. K., Yanny, B., Yin, B., Zhang, Y., and Zuntz, J.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We present cosmological constraints from the analysis of two-point correlation functions between galaxy positions and galaxy lensing measured in Dark Energy Survey (DES) Year 3 data and measurements of cosmic microwave background (CMB) lensing from the South Pole Telescope (SPT) and Planck. When jointly analyzing the DES-only two-point functions and the DES cross-correlations with SPT+Planck CMB lensing, we find $\Omega_{\rm m} = 0.344\pm 0.030$ and $S_8 \equiv \sigma_8 (\Omega_{\rm m}/0.3)^{0.5} = 0.773\pm 0.016$, assuming $\Lambda$CDM. When additionally combining with measurements of the CMB lensing autospectrum, we find $\Omega_{\rm m} = 0.306^{+0.018}_{-0.021}$ and $S_8 = 0.792\pm 0.012$. The high signal-to-noise of the CMB lensing cross-correlations enables several powerful consistency tests of these results, including comparisons with constraints derived from cross-correlations only, and comparisons designed to test the robustness of the galaxy lensing and clustering measurements from DES. Applying these tests to our measurements, we find no evidence of significant biases in the baseline cosmological constraints from the DES-only analyses or from the joint analyses with CMB lensing cross-correlations. However, the CMB lensing cross-correlations suggest possible problems with the correlation function measurements using alternative lens galaxy samples, in particular the redMaGiC galaxies and high-redshift MagLim galaxies, consistent with the findings of previous studies. We use the CMB lensing cross-correlations to identify directions for further investigating these problems., Comment: 20 pages, 15 figures
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- 2022
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157. Correction: Romanticizing decolonization and Asian epistemology: reflections on identity and space
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Lee, Jack T.
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- 2024
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158. Lipidomics profiling of biological aging in American Indians: the Strong Heart Family Study
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Subedi, Pooja, Palma-Gudiel, Helena, Fiehn, Oliver, Best, Lyle G, Lee, Elisa T, Howard, Barbara V, and Zhao, Jinying
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Aging ,Prevention ,Cardiovascular ,Heart Disease ,Humans ,Lipidomics ,American Indian or Alaska Native ,Indians ,North American ,Lipids ,Biological aging ,Telomere length ,Biomarkers ,American Indians ,Strong Heart Study - Abstract
Telomeres shorten with age and shorter leukocyte telomere length (LTL) has been associated with various age-related diseases. Thus, LTL has been considered a biomarker of biological aging. Dyslipidemia is an established risk factor for most age-related metabolic disorders. However, little is known about the relationship between LTL and dyslipidemia. Lipidomics is a new biochemical technique that can simultaneously identify and quantify hundreds to thousands of small molecular lipid species. In a large population comprising 1843 well-characterized American Indians in the Strong Heart Family Study, we examined the lipidomic profile of biological aging assessed by LTL. Briefly, LTL was quantified by qPCR. Fasting plasma lipids were quantified by untargeted liquid chromatography-mass spectrometry. Lipids associated with LTL were identified by elastic net modeling. Of 1542 molecular lipids identified (518 known, 1024 unknown), 174 lipids (36 knowns) were significantly associated with LTL, independent of chronological age, sex, BMI, hypertension, diabetes status, smoking status, bulk HDL-C, and LDL-C. These findings suggest that altered lipid metabolism is associated with biological aging and provide novel insights that may enhance our understanding of the relationship between dyslipidemia, biological aging, and age-related diseases in American Indians.
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- 2023
159. The UCSC Genome Browser database: 2023 update
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Nassar, Luis R, Barber, Galt P, Benet-Pagès, Anna, Casper, Jonathan, Clawson, Hiram, Diekhans, Mark, Fischer, Clay, Gonzalez, Jairo Navarro, Hinrichs, Angie S, Lee, Brian T, Lee, Christopher M, Muthuraman, Pranav, Nguy, Beagan, Pereira, Tiana, Nejad, Parisa, Perez, Gerardo, Raney, Brian J, Schmelter, Daniel, Speir, Matthew L, Wick, Brittney D, Zweig, Ann S, Haussler, David, Kuhn, Robert M, Haeussler, Maximilian, and Kent, W James
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Biological Sciences ,Bioinformatics and Computational Biology ,Genetics ,Human Genome ,Networking and Information Technology R&D (NITRD) ,Biotechnology ,1.5 Resources and infrastructure (underpinning) ,2.6 Resources and infrastructure (aetiology) ,Humans ,COVID-19 ,Databases ,Genetic ,Genomics ,Internet ,Phylogeny ,SARS-CoV-2 ,Software ,Web Browser ,Environmental Sciences ,Information and Computing Sciences ,Developmental Biology ,Biological sciences ,Chemical sciences ,Environmental sciences - Abstract
The UCSC Genome Browser (https://genome.ucsc.edu) is an omics data consolidator, graphical viewer, and general bioinformatics resource that continues to serve the community as it enters its 23rd year. This year has seen an emphasis in clinical data, with new tracks and an expanded Recommended Track Sets feature on hg38 as well as the addition of a single cell track group. SARS-CoV-2 continues to remain a focus, with regular annotation updates to the browser and continued curation of our phylogenetic sequence placing tool, hgPhyloPlace, whose tree has now reached over 12M sequences. Our GenArk resource has also grown, offering over 2500 hubs and a system for users to request any absent assemblies. We have expanded our bigBarChart display type and created new ways to visualize data via bigRmsk and dynseq display. Displaying custom annotations is now easier due to our chromAlias system which eliminates the requirement for renaming sequence names to the UCSC standard. Users involved in data generation may also be interested in our new tools and trackDb settings which facilitate the creation and display of their custom annotations.
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- 2023
160. It's usually not worth the effort unless you get really lucky": Barriers to Undergraduate Research Experiences from the Perspective of Computing Faculty
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Sharma, Rhea, Nair, Atira, Guo, Ana, Palea, Dustin, and Lee, David T
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Undergraduate Research Experiences ,Computing Education ,Misalignments ,Designing Systems - Published
- 2023
161. Telomere length associates with chronological age and mortality across racially diverse pulmonary fibrosis cohorts
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Adegunsoye, Ayodeji, Newton, Chad A, Oldham, Justin M, Ley, Brett, Lee, Cathryn T, Linderholm, Angela L, Chung, Jonathan H, Garcia, Nicole, Zhang, Da, Vij, Rekha, Guzy, Robert, Jablonski, Renea, Bag, Remzi, Voogt, Rebecca S, Ma, Shwu-Fan, Sperling, Anne I, Raghu, Ganesh, Martinez, Fernando J, Strek, Mary E, Wolters, Paul J, Garcia, Christine Kim, Pierce, Brandon L, and Noth, Imre
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Epidemiology ,Biomedical and Clinical Sciences ,Health Sciences ,Clinical Research ,Minority Health ,Good Health and Well Being ,Humans ,Pulmonary Fibrosis ,Ethnicity ,Proportional Hazards Models ,Racial Groups ,Telomere ,Leukocytes - Abstract
Pulmonary fibrosis (PF) is characterized by profound scarring and poor survival. We investigated the association of leukocyte telomere length (LTL) with chronological age and mortality across racially diverse PF cohorts. LTL measurements among participants with PF stratified by race/ethnicity were assessed in relation to age and all-cause mortality, and compared to controls. Generalized linear models were used to evaluate the age-LTL relationship, Cox proportional hazards models were used for hazard ratio estimation, and the Cochran-Armitage test was used to assess quartiles of LTL. Standardized LTL shortened with increasing chronological age; this association in controls was strengthened in PF (R = -0.28; P
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- 2023
162. Fluorogenic reporter enables identification of compounds that inhibit SARS-CoV-2
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Yang, Junjiao, Xiao, Yinghong, Lidsky, Peter V, Wu, Chien-Ting, Bonser, Luke R, Peng, Shiming, Garcia-Knight, Miguel A, Tassetto, Michel, Chung, Chan-I, Li, Xiaoquan, Nakayama, Tsuguhisa, Lee, Ivan T, Nayak, Jayakar V, Ghias, Khadija, Hargett, Kirsten L, Shoichet, Brian K, Erle, David J, Jackson, Peter K, Andino, Raul, and Shu, Xiaokun
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Biological Sciences ,Bioinformatics and Computational Biology ,Coronaviruses ,Emerging Infectious Diseases ,Biotechnology ,Coronaviruses Therapeutics and Interventions ,Infectious Diseases ,Lung ,5.1 Pharmaceuticals ,2.1 Biological and endogenous factors ,Respiratory ,Good Health and Well Being ,Chlorocebus aethiops ,Mice ,Humans ,Animals ,SARS-CoV-2 ,COVID-19 ,Vero Cells ,Angiotensin-Converting Enzyme 2 ,Peptidyl-Dipeptidase A ,Antiviral Agents ,Microbiology ,Medical Microbiology - Abstract
The coronavirus SARS-CoV-2 causes the severe disease COVID-19. SARS-CoV-2 infection is initiated by interaction of the viral spike protein and host receptor angiotensin-converting enzyme 2 (ACE2). We report an improved bright and reversible fluorogenic reporter, named SURF (split UnaG-based reversible and fluorogenic protein-protein interaction reporter), that we apply to monitor real-time interactions between spike and ACE2 in living cells. SURF has a large dynamic range with a dark-to-bright fluorescence signal that requires no exogenous cofactors. Utilizing this reporter, we carried out a high-throughput screening of small-molecule libraries. We identified three natural compounds that block replication of SARS-CoV-2 in both Vero cells and human primary nasal and bronchial epithelial cells. Cell biological and biochemical experiments validated all three compounds and showed that they block the early stages of viral infection. Two of the inhibitors, bruceine A and gamabufotalin, were also found to block replication of the Delta and Omicron variants of SARS-CoV-2. Both bruceine A and gamabufotalin exhibited potent antiviral activity in K18-hACE2 and wild-type C57BL6/J mice, as evidenced by reduced viral titres in the lung and brain, and protection from alveolar and peribronchial inflammation in the lung, thereby limiting disease progression. We propose that our fluorescent assay can be applied to identify antiviral compounds with potential as therapeutic treatment for COVID-19 and other respiratory diseases.
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- 2023
163. Trash Talk: Anti-Obama Lore and Race in the Twenty-First Century
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Lee, Steven T.
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University of California Press ,Publishing industry ,Publishing industry ,Anthropology/archeology/folklore ,Regional focus/area studies - Abstract
Trash Talk: Anti-Obama Lore and Race in the Twenty-First Century. Patricia A. Turner. (Oakland: University of California Press, 2022. Pp. 206, figures, tables, acknowledgments, notes, bibliography, index. $29.95 paper.) This [...]
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- 2024
164. Recent Developments of Commercially Fabricated Horn Antenna-Coupled Transition-Edge Sensor Bolometer Detectors for Next-Generation Cosmic Microwave Background Polarimetry Experiments
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Suzuki, Aritoki, Kane, Elijah, Lee, Adrian T, Liu, Tiffany, Raum, Christopher, Renzullo, Mario, Truitt, Patrick, Vivalda, John, Westbrook, Benjamin, and Yohannes, Daniel
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Nuclear and Plasma Physics ,Physical Sciences ,Cosmic microwave background ,TES bolometer ,Fabrication ,Technology transfer ,Mathematical Physics ,Classical Physics ,Condensed Matter Physics ,General Physics ,Classical physics ,Condensed matter physics - Abstract
We report on the successful fabrication of orthomode transducer-coupled transition-edge sensor (TES) bolometer arrays for cosmic microwave background (CMB) polarimetry experiments with the superconductor electronics fabrication facility at SEEQC Inc. Commercial microfabrication foundry could provide increase in detector fabrication throughput for a next-generation CMB experiment, CMB-S4, that would deploy approximately one order of magnitude more detectors than current CMB experiments. We also developed TES bolometers with two TESs in series that have two different superconducting temperatures (Tc) using a superconducting proximity effect between niobium (Nb) and aluminum-manganese (AlMn) alloy. We will discuss the motivation, design considerations, fabrication processes, test results, and how industrial detector fabrication could be a path to fabricate hundreds of detector wafers for future CMB polarimetry experiments and other experiments that require TESs and superconducting RF circuits.
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- 2022
165. Audit of Postoperative Readmissions and Patient Messages following Endoscopic Transnasal Transsphenoidal Surgery
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Harary, Maya, Bommakanti, Krishna K, Nakhla, Morcos N, Kosaraju, Nikitha, Heaney, Anthony P, Kim, Won, Lee, Jivianne T, Suh, Jeffrey D, Bergsneider, Marvin, and Wang, Marilene B
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Clinical Research ,Health Services ,Patient Safety ,Cancer ,8.1 Organisation and delivery of services ,Management of diseases and conditions ,7.1 Individual care needs ,Health and social care services research ,endoscopic skull base surgery ,TNTS ,discharge instructions ,readmissions ,Neurology & Neurosurgery - Abstract
Objectives The aim of this study was to identify the reasons for patient messages, phone calls, and emergency department (ED) visits prior to the first postoperative visit following discharge after endoscopic transnasal transsphenoidal (eTNTS) surgery. Design This is a retrospective review of patients at a tertiary care academic center who underwent eTNTS for resection of a sellar region tumor between May 2020 and August 2021. Patient, tumor, and surgical characteristics were collected, along with postoperative, postdischarge, and readmission information. Regression analyses were performed to investigate risk factors associated with postdischarge phone calls, messages, ED visits, and readmissions. Main Outcome Measures The main outcomes were the number of and reasons for phone calls, patient messages, and ED visits between hospital discharge and the first postoperative visit. We additionally determined whether these reasons were addressed in each patient's discharge instructions. Results A total of 98 patients underwent eTNTS during the study period. The median length of hospital stay was 2 days (interquartile range [IQR]: 1-4 days), at which point most patients (82%) were provided with eTNTS-specific discharge instructions. First postoperative visit took place 9 days after discharge (IQR: 7-10 days). Within that time, 54% of patients made at least one phone call or sent at least electronic message and 17% presented to the ED. Most common reasons for call/message were nasal care, appointment scheduling, and symptom and medication questions. Conclusion Through this work, we highlight the most common reasons for resource utilization via patient phone calls, messages, and ED visits among our cohort to better understand any shortfall or gap in the discharge process that may reduce these events.
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- 2022
166. Endoscopic endonasal approach for resection of a recurrent spheno-orbital meningioma resulting in complete resolution of visual symptoms: A case report and review of literature
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Kim, Won, Ghodrati, Farinaz, Mozaffari, Khashayar, Samarage, H Milan, Zhang, Ashley B, Pradhan, Anjali, Lee, Jivianne T, Goldberg, Robert A, and Yang, Isaac
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Biomedical and Clinical Sciences ,Clinical Sciences ,Ophthalmology and Optometry ,Rare Diseases ,Brain Disorders ,Neurosciences ,Cancer ,Eye Disease and Disorders of Vision ,Patient Safety ,Clinical Research ,Brain Cancer ,Humans ,Female ,Adult ,Middle Aged ,Aged ,Aged ,80 and over ,Male ,Meningioma ,Sphenoid Bone ,Orbital Neoplasms ,Neurosurgical Procedures ,Treatment Outcome ,Neoplasm Recurrence ,Local ,Meningeal Neoplasms ,Retrospective Studies ,Spheno-orbital meningioma ,Endonasal ,Endoscopic approach ,Neurosurgery ,Optic tract ,Vision loss ,Oncology and Carcinogenesis ,Oncology & Carcinogenesis ,Oncology and carcinogenesis - Abstract
PurposeSpheno-orbital meningiomas are rare tumors, accounting for up to 9% of all intracranial meningiomas. Patients commonly present with proptosis, and visual deficits. These slow growing tumors are hard to resect due to extension into several anatomical compartments, resulting in recurrence rates as high as 35-50%. Although open surgical approaches have been historically used for resection, a handful of endoscopic approaches have been reported in recent years. We aimed to review the literature and describe a case of spheno-orbital meningioma with severe vision loss which was resected with an endoscopic endonasal approach achieving complete resolution of visual symptoms.MethodsA systematic review of literature was conducted in accordance with the PRISMA guidelines. PubMed, Cochrane, and Web of Science databases were queried for spheno-orbital meningiomas resected via an endoscopic endonasal approach. Furthermore, the presentation, surgical management, and post-operative outcomes of a 53-year-old female with a recurrent spheno-orbital meningioma are described.ResultsThe search yielded 26 articles, of which 8 were included, yielding 19 cases. Average age at presentation was 60.5 years (range: 44-82), and 68.4% of patients were female. More than half of the cases achieved subtotal resection. Common complications associated with endoscopic endonasal surgery included CN V2 or CN V2/V3 hypoesthesia. Following surgical intervention, visual acuity and visual field remained stable or improved in the majority of the patients.ConclusionEndoscopic approaches are slowly gaining momentum for treatment of spheno-orbital meningiomas. Further studies on the clinical benefits of this approach on patient outcomes and post-operative complications is warranted.
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- 2022
167. How does engagement on social media reinforce life aesthetic literacy? The role of interpersonal and intrapersonal influences
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Pan, Ling-Yen and Lee, Crystal T.
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- 2024
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168. The actions of varenicline on alkaloids from Conium maculatum (poison hemlock), Lupinus sulphureus (sulphur lupine) and Nicotiana glauca (tree tobacco)
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Green, Benedict T., Lee, Stephen T., Welch, Kevin D., Cook, Daniel, and Stonecipher, Clinton A.
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- 2024
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169. The evaluation of earwax as a noninvasive specimen to determine livestock exposure to death camas (Zigadenuspaniculatus)
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Lee, Stephen T., Stonecipher, Clinton A., Welch, Kevin D., and Cook, Daniel
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- 2024
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170. Obesity-Related Biases Among Health-Care Personnel in Radiological Examination Environment: Impact, Manifestations, and Solutions
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Mathews, Nisha, Joseph, Jolly, Joseph, Maya E., Munoz, Elizabeth G., and Lee, Loretta T.
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- 2024
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171. Psychological hardiness, social support, and emotional labor among nurses in Iran during the COVID-19 pandemic: A cross-sectional survey study
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SAEI, Elham and LEE, Raymond T.
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- 2024
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172. Love as a concept in academic research: A bibliometric review
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Cebral-Loureda, Manuel, Lee, Mathew T., Hernández-Baqueiro, Alberto, Lomas, Tim, and Tamés-Muñoz, Enrique
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- 2024
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173. Exploring determinants of non-fungible token creators’ engagement behaviors on metaverse-based NFT platforms: A multi-analytical SEM-IPMA method
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Lee, Crystal T. and Shen, Yung-Cheng
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- 2024
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174. Artificial humanity: A multi-method exploration of user responses to AI influencer affordances in short video platform
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Lee, Crystal T. and Shen, Yung-Cheng
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- 2025
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175. Creativity ambidexterity and sustainable business: Taking advantage of creative thinking techniques
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Lee, Michael T., Kachen, Sheen, Krishen, Anjala S., and Raschke, Robyn L.
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- 2025
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176. Predictors of mortality among sepsis patients transferred from a rural, low-volume ED to an urban, high-volume hospital
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Ameripour, Arman, Herrera, Elizabeth, Coskey, Olivia, Ng, Justin, Cornejo Ochoa, Cesar, Modesette, Allison, Lee, Jenny T., Chun, Truman Ray K.G.C., Kaur, Jasmeet, Hertel, Andrew W., Smith, Barry C., and Delmonaco, Brian L.
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- 2025
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177. Consistent patterns of common species across tropical tree communities
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Cooper, Declan L. M., Lewis, Simon L., Sullivan, Martin J. P., Prado, Paulo I., ter Steege, Hans, Barbier, Nicolas, Slik, Ferry, Sonké, Bonaventure, Ewango, Corneille E. N., Adu-Bredu, Stephen, Affum-Baffoe, Kofi, de Aguiar, Daniel P. P., Ahuite Reategui, Manuel Augusto, Aiba, Shin-Ichiro, Albuquerque, Bianca Weiss, de Almeida Matos, Francisca Dionízia, Alonso, Alfonso, Amani, Christian A., do Amaral, Dário Dantas, do Amaral, Iêda Leão, Andrade, Ana, de Andrade Miranda, Ires Paula, Angoboy, Ilondea B., Araujo-Murakami, Alejandro, Arboleda, Nicolás Castaño, Arroyo, Luzmila, Ashton, Peter, Aymard C, Gerardo A., Baider, Cláudia, Baker, Timothy R., Balinga, Michael Philippe Bessike, Balslev, Henrik, Banin, Lindsay F., Bánki, Olaf S., Baraloto, Chris, Barbosa, Edelcilio Marques, Barbosa, Flávia Rodrigues, Barlow, Jos, Bastin, Jean-Francois, Beeckman, Hans, Begne, Serge, Bengone, Natacha Nssi, Berenguer, Erika, Berry, Nicholas, Bitariho, Robert, Boeckx, Pascal, Bogaert, Jan, Bonyoma, Bernard, Boundja, Patrick, Bourland, Nils, Boyemba Bosela, Faustin, Brambach, Fabian, Brienen, Roel, Burslem, David F. R. P., Camargo, José Luís, Campelo, Wegliane, Cano, Angela, Cárdenas, Sasha, Cárdenas López, Dairon, de Sá Carpanedo, Rainiellen, Carrero Márquez, Yrma Andreina, Carvalho, Fernanda Antunes, Casas, Luisa Fernanda, Castellanos, Hernán, Castilho, Carolina V., Cerón, Carlos, Chapman, Colin A., Chave, Jerome, Chhang, Phourin, Chutipong, Wanlop, Chuyong, George B., Cintra, Bruno Barçante Ladvocat, Clark, Connie J., Coelho de Souza, Fernanda, Comiskey, James A., Coomes, David A., Cornejo Valverde, Fernando, Correa, Diego F., Costa, Flávia R. C., Costa, Janaina Barbosa Pedrosa, Couteron, Pierre, Culmsee, Heike, Cuni-Sanchez, Aida, Dallmeier, Francisco, Damasco, Gabriel, Dauby, Gilles, Dávila, Nállarett, Dávila Doza, Hilda Paulette, De Alban, Jose Don T., de Assis, Rafael L., De Canniere, Charles, De Haulleville, Thales, de Jesus Veiga Carim, Marcelo, Demarchi, Layon O., Dexter, Kyle G., Di Fiore, Anthony, Din, Hazimah Haji Mohammad, Disney, Mathias I., Djiofack, Brice Yannick, Djuikouo, Marie-Noël K., Do, Tran Van, Doucet, Jean-Louis, Draper, Freddie C., Droissart, Vincent, Duivenvoorden, Joost F., Engel, Julien, Estienne, Vittoria, Farfan-Rios, William, Fauset, Sophie, Feeley, Kenneth J., Feitosa, Yuri Oliveira, Feldpausch, Ted R., Ferreira, Cid, Ferreira, Joice, Ferreira, Leandro Valle, Fletcher, Christine D., Flores, Bernardo Monteiro, Fofanah, Alusine, Foli, Ernest G., Fonty, Émile, Fredriksson, Gabriella M., Fuentes, Alfredo, Galbraith, David, Gallardo Gonzales, George Pepe, Garcia-Cabrera, Karina, García-Villacorta, Roosevelt, Gomes, Vitor H. F., Gómez, Ricardo Zárate, Gonzales, Therany, Gribel, Rogerio, Guedes, Marcelino Carneiro, Guevara, Juan Ernesto, Hakeem, Khalid Rehman, Hall, Jefferson S., Hamer, Keith C., Hamilton, Alan C., Harris, David J., Harrison, Rhett D., Hart, Terese B., Hector, Andy, Henkel, Terry W., Herbohn, John, Hockemba, Mireille B. N., Hoffman, Bruce, Holmgren, Milena, Honorio Coronado, Euridice N., Huamantupa-Chuquimaco, Isau, Hubau, Wannes, Imai, Nobuo, Irume, Mariana Victória, Jansen, Patrick A., Jeffery, Kathryn J., Jimenez, Eliana M., Jucker, Tommaso, Junqueira, André Braga, Kalamandeen, Michelle, Kamdem, Narcisse G., Kartawinata, Kuswata, Kasongo Yakusu, Emmanuel, Katembo, John M., Kearsley, Elizabeth, Kenfack, David, Kessler, Michael, Khaing, Thiri Toe, Killeen, Timothy J., Kitayama, Kanehiro, Klitgaard, Bente, Labrière, Nicolas, Laumonier, Yves, Laurance, Susan G. W., Laurance, William F., Laurent, Félix, Le, Tinh Cong, Le, Trai Trong, Leal, Miguel E., Leão de Moraes Novo, Evlyn Márcia, Levesley, Aurora, Libalah, Moses B., Licona, Juan Carlos, Lima Filho, Diógenes de Andrade, Lindsell, Jeremy A., Lopes, Aline, Lopes, Maria Aparecida, Lovett, Jon C., Lowe, Richard, Lozada, José Rafael, Lu, Xinghui, Luambua, Nestor K., Luize, Bruno Garcia, Maas, Paul, Magalhães, José Leonardo Lima, Magnusson, William E., Mahayani, Ni Putu Diana, Makana, Jean-Remy, Malhi, Yadvinder, Maniguaje Rincón, Lorena, Mansor, Asyraf, Manzatto, Angelo Gilberto, Marimon, Beatriz S., Marimon-Junior, Ben Hur, Marshall, Andrew R, Martins, Maria Pires, Mbayu, Faustin M., de Medeiros, Marcelo Brilhante, Mesones, Italo, Metali, Faizah, Mihindou, Vianet, Millet, Jerome, Milliken, William, Mogollón, Hugo F., Molino, Jean-François, Mohd. Said, Mohd. Nizam, Monteagudo Mendoza, Abel, Montero, Juan Carlos, Moore, Sam, Mostacedo, Bonifacio, Mozombite Pinto, Linder Felipe, Mukul, Sharif Ahmed, Munishi, Pantaleo K. T., Nagamasu, Hidetoshi, Nascimento, Henrique Eduardo Mendonça, Nascimento, Marcelo Trindade, Neill, David, Nilus, Reuben, Noronha, Janaína Costa, Nsenga, Laurent, Núñez Vargas, Percy, Ojo, Lucas, Oliveira, Alexandre A., de Oliveira, Edmar Almeida, Ondo, Fidèle Evouna, Palacios Cuenca, Walter, Pansini, Susamar, Pansonato, Marcelo Petratti, Paredes, Marcos Ríos, Paudel, Ekananda, Pauletto, Daniela, Pearson, Richard G., Pena, José Luis Marcelo, Pennington, R. Toby, Peres, Carlos A., Permana, Andrea, Petronelli, Pascal, Peñuela Mora, Maria Cristina, Phillips, Juan Fernando, Phillips, Oliver L., Pickavance, Georgia, Piedade, Maria Teresa Fernandez, Pitman, Nigel C. A., Ploton, Pierre, Popelier, Andreas, Poulsen, John R., Prieto, Adriana, Primack, Richard B., Priyadi, Hari, Qie, Lan, Quaresma, Adriano Costa, de Queiroz, Helder Lima, Ramirez-Angulo, Hirma, Ramos, José Ferreira, Reis, Neidiane Farias Costa, Reitsma, Jan, Revilla, Juan David Cardenas, Riutta, Terhi, Rivas-Torres, Gonzalo, Robiansyah, Iyan, Rocha, Maira, Rodrigues, Domingos de Jesus, Rodriguez-Ronderos, M. Elizabeth, Rovero, Francesco, Rozak, Andes H., Rudas, Agustín, Rutishauser, Ervan, Sabatier, Daniel, Sagang, Le Bienfaiteur, Sampaio, Adeilza Felipe, Samsoedin, Ismayadi, Satdichanh, Manichanh, Schietti, Juliana, Schöngart, Jochen, Scudeller, Veridiana Vizoni, Seuaturien, Naret, Sheil, Douglas, Sierra, Rodrigo, Silman, Miles R., Silva, Thiago Sanna Freire, da Silva Guimarães, José Renan, Simo-Droissart, Murielle, Simon, Marcelo Fragomeni, Sist, Plinio, Sousa, Thaiane R., de Sousa Farias, Emanuelle, de Souza Coelho, Luiz, Spracklen, Dominick V., Stas, Suzanne M., Steinmetz, Robert, Stevenson, Pablo R., Stropp, Juliana, Sukri, Rahayu S., Sunderland, Terry C. H., Suzuki, Eizi, Swaine, Michael D., Tang, Jianwei, Taplin, James, Taylor, David M., Tello, J. Sebastián, Terborgh, John, Texier, Nicolas, Theilade, Ida, Thomas, Duncan W., Thomas, Raquel, Thomas, Sean C., Tirado, Milton, Toirambe, Benjamin, de Toledo, José Julio, Tomlinson, Kyle W., Torres-Lezama, Armando, Tran, Hieu Dang, Tshibamba Mukendi, John, Tumaneng, Roven D., Umaña, Maria Natalia, Umunay, Peter M., Urrego Giraldo, Ligia Estela, Valderrama Sandoval, Elvis H., Valenzuela Gamarra, Luis, Van Andel, Tinde R., van de Bult, Martin, van de Pol, Jaqueline, van der Heijden, Geertje, Vasquez, Rodolfo, Vela, César I. A., Venticinque, Eduardo Martins, Verbeeck, Hans, Veridiano, Rizza Karen A., Vicentini, Alberto, Vieira, Ima Célia Guimarães, Vilanova Torre, Emilio, Villarroel, Daniel, Villa Zegarra, Boris Eduardo, Vleminckx, Jason, von Hildebrand, Patricio, Vos, Vincent Antoine, Vriesendorp, Corine, Webb, Edward L., White, Lee J. T., Wich, Serge, Wittmann, Florian, Zagt, Roderick, Zang, Runguo, Zartman, Charles Eugene, Zemagho, Lise, Zent, Egleé L., and Zent, Stanford
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- 2024
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178. Searching for axion-like time-dependent cosmic birefringence with data from SPT-3G
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Ferguson, K. R., Anderson, A. J., Whitehorn, N., Ade, P. A. R., Archipley, M., Avva, J. S., Balkenhol, L., Benabed, K., Bender, A. N., Benson, B. A., Bianchini, F., Bleem, L. E., Bouchet, F. R., Bryant, L., Camphuis, E., Carlstrom, J. E., Cecil, T. W., Chang, C. L., Chaubal, P., Chichura, P. M., Chou, T. -L., Crawford, T. M., Cukierman, A., Daley, C., de Haan, T., Dibert, K., Dobbs, M. A., Doussot, A., Dutcher, D., Everett, W., Feng, C., Foster, A., Galli, S., Gambrel, A. E., Gardner, R. W., Goeckner-Wald, N., Gualtieri, R., Guidi, F., Guns, S., Halverson, N. W., Hivon, E., Holder, G. P., Holzapfel, W. L., Hood, J. C., Huang, N., Knox, L., Korman, M., Kuo, C. -L., Lee, A. T., Lowitz, A. E., Lu, C., Millea, M., Montgomery, J., Natoli, T., Noble, G. I., Novosad, V., Omori, Y., Padin, S., Pan, Z., Paschos, P., Prabhu, K., Quan, W., Rahlin, A., Reichardt, C. L., Rouble, M., Ruhl, J. E., Schiappucci, E., Smecher, G., Sobrin, J. A., Stephen, J., Suzuki, A., Tandoi, C., Thompson, K. L., Thorne, B., Tucker, C., Umilta, C., Vieira, J. D., Wang, G., Wu, W. L. K., Yefremenko, V., and Young, M. R.
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Astrophysics - Cosmology and Nongalactic Astrophysics ,High Energy Physics - Experiment - Abstract
Ultralight axionlike particles (ALPs) are compelling dark matter candidates because of their potential to resolve small-scale discrepancies between $\Lambda$CDM predictions and cosmological observations. Axion-photon coupling induces a polarization rotation in linearly polarized photons traveling through an ALP field; thus, as the local ALP dark matter field oscillates in time, distant static polarized sources will appear to oscillate with a frequency proportional to the ALP mass. We use observations of the cosmic microwave background from SPT-3G, the current receiver on the South Pole Telescope, to set upper limits on the value of the axion-photon coupling constant $g_{\phi\gamma}$ over the approximate mass range $10^{-22} - 10^{-19}$ eV, corresponding to oscillation periods from 12 hours to 100 days. For periods between 1 and 100 days ($4.7 \times 10^{-22} \text{ eV} \leq m_\phi \leq 4.7 \times 10^{-20} \text{ eV}$), where the limit is approximately constant, we set a median 95% C.L. upper limit on the amplitude of on-sky polarization rotation of 0.071 deg. Assuming that dark matter comprises a single ALP species with a local dark matter density of $0.3\text{ GeV/cm}^3$, this corresponds to $g_{\phi\gamma} < 1.18 \times 10^{-12}\text{ GeV}^{-1} \times \left( \frac{m_{\phi}}{1.0 \times 10^{-21} \text{ eV}} \right)$. These new limits represent an improvement over the previous strongest limits set using the same effect by a factor of ~3.8., Comment: 16 pages, 5 figures. Accepted for publication in Physical Review D
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- 2022
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179. Joint analysis of DES Year 3 data and CMB lensing from SPT and Planck II: Cross-correlation measurements and cosmological constraints
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Chang, C., Omori, Y., Baxter, E. J., Doux, C., Choi, A., Pandey, S., Alarcon, A., Alves, O., Amon, A., Andrade-Oliveira, F., Bechtol, K., Becker, M. R., Bernstein, G. M., Bianchini, F., Blazek, J., Bleem, L. E., Camacho, H., Campos, A., Rosell, A. Carnero, Kind, M. Carrasco, Cawthon, R., Chen, R., Cordero, J., Crawford, T. M., Crocce, M., Davis, C., DeRose, J., Dodelson, S., Drlica-Wagner, A., Eckert, K., Eifler, T. F., Elsner, F., Elvin-Poole, J., Everett, S., Fang, X., Ferté, A., Fosalba, P., Friedrich, O., Gatti, M., Giannini, G., Gruen, D., Gruendl, R. A., Harrison, I., Herner, K., Huang, H., Huff, E. M., Huterer, D., Jarvis, M., Kovacs, A., Krause, E., Kuropatkin, N., Leget, P. -F., Lemos, P., Liddle, A. R., MacCrann, N., McCullough, J., Muir, J., Myles, J., Navarro-Alsina, A., Park, Y., Porredon, A., Prat, J., Raveri, M., Rollins, R. P., Roodman, A., Rosenfeld, R., Ross, A. J., Rykoff, E. S., Sánchez, C., Sanchez, J., Secco, L. F., Sevilla-Noarbe, I., Sheldon, E., Shin, T., Troxel, M. A., Tutusaus, I., Varga, T. N., Weaverdyck, N., Wechsler, R. H., Wu, W. L. K., Yanny, B., Yin, B., Zhang, Y., Zuntz, J., Abbott, T. M. C., Aguena, M., Allam, S., Annis, J., Bacon, D., Benson, B. A., Bertin, E., Bocquet, S., Brooks, D., Burke, D. L., Carlstrom, J. E., Carretero, J., Chang, C. L., Chown, R., Costanzi, M., da Costa, L. N., Crites, A. T., Pereira, M. E. S., de Haan, T., De Vicente, J., Desai, S., Diehl, H. T., Dobbs, M. A., Doel, P., Everett, W., Ferrero, I., Flaugher, B., Friedel, D., Frieman, J., García-Bellido, J., Gaztanaga, E., George, E. M., Giannantonio, T., Halverson, N. W., Hinton, S. R., Holder, G. P., Hollowood, D. L., Holzapfel, W. L., Honscheid, K., Hrubes, J. D., James, D. J., Knox, L., Kuehn, K., Lahav, O., Lee, A. T., Lima, M., Luong-Van, D., March, M., McMahon, J. J., Melchior, P., Menanteau, F., Meyer, S. S., Miquel, R., Mocanu, L., Mohr, J. J., Morgan, R., Natoli, T., Padin, S., Palmese, A., Paz-Chinchón, F., Pieres, A., Malagón, A. A. Plazas, Pryke, C., Reichardt, C. L., Rodríguez-Monroy, M., Romer, A. K., Ruhl, J. E., Sanchez, E., Schaffer, K. K., Schubnell, M., Serrano, S., Shirokoff, E., Smith, M., Staniszewski, Z., Stark, A. A., Suchyta, E., Tarle, G., Thomas, D., To, C., Vieira, J. D., Weller, J., and Williamson, R.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
Cross-correlations of galaxy positions and galaxy shears with maps of gravitational lensing of the cosmic microwave background (CMB) are sensitive to the distribution of large-scale structure in the Universe. Such cross-correlations are also expected to be immune to some of the systematic effects that complicate correlation measurements internal to galaxy surveys. We present measurements and modeling of the cross-correlations between galaxy positions and galaxy lensing measured in the first three years of data from the Dark Energy Survey with CMB lensing maps derived from a combination of data from the 2500 deg$^2$ SPT-SZ survey conducted with the South Pole Telescope and full-sky data from the Planck satellite. The CMB lensing maps used in this analysis have been constructed in a way that minimizes biases from the thermal Sunyaev Zel'dovich effect, making them well suited for cross-correlation studies. The total signal-to-noise of the cross-correlation measurements is 23.9 (25.7) when using a choice of angular scales optimized for a linear (nonlinear) galaxy bias model. We use the cross-correlation measurements to obtain constraints on cosmological parameters. For our fiducial galaxy sample, which consist of four bins of magnitude-selected galaxies, we find constraints of $\Omega_{m} = 0.272^{+0.032}_{-0.052}$ and $S_{8} \equiv \sigma_8 \sqrt{\Omega_{m}/0.3}= 0.736^{+0.032}_{-0.028}$ ($\Omega_{m} = 0.245^{+0.026}_{-0.044}$ and $S_{8} = 0.734^{+0.035}_{-0.028}$) when assuming linear (nonlinear) galaxy bias in our modeling. Considering only the cross-correlation of galaxy shear with CMB lensing, we find $\Omega_{m} = 0.270^{+0.043}_{-0.061}$ and $S_{8} = 0.740^{+0.034}_{-0.029}$. Our constraints on $S_8$ are consistent with recent cosmic shear measurements, but lower than the values preferred by primary CMB measurements from Planck., Comment: 25 pages, 19 figures, submitted to PRD
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- 2022
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180. Joint analysis of DES Year 3 data and CMB lensing from SPT and Planck I: Construction of CMB Lensing Maps and Modeling Choices
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Omori, Y., Baxter, E. J., Chang, C., Friedrich, O., Alarcon, A., Alves, O., Amon, A., Andrade-Oliveira, F., Bechtol, K., Becker, M. R., Bernstein, G. M., Blazek, J., Bleem, L. E., Camacho, H., Campos, A., Rosell, A. Carnero, Kind, M. Carrasco, Cawthon, R., Chen, R., Choi, A., Cordero, J., Crawford, T. M., Crocce, M., Davis, C., DeRose, J., Dodelson, S., Doux, C., Drlica-Wagner, A., Eckert, K., Eifler, T. F., Elsner, F., Elvin-Poole, J., Everett, S., Fang, X., Ferté, A., Fosalba, P., Gatti, M., Giannini, G., Gruen, D., Gruendl, R. A., Harrison, I., Herner, K., Huang, H., Huff, E. M., Huterer, D., Jarvis, M., Krause, E., Kuropatkin, N., Leget, P. -F., Lemos, P., Liddle, A. R., MacCrann, N., McCullough, J., Muir, J., Myles, J., Navarro-Alsina, A., Pandey, S., Park, Y., Porredon, A., Prat, J., Raveri, M., Rollins, R. P., Roodman, A., Rosenfeld, R., Ross, A. J., Rykoff, E. S., Sánchez, C., Sanchez, J., Secco, L. F., Sevilla-Noarbe, I., Sheldon, E., Shin, T., Troxel, M. A., Tutusaus, I., Varga, T. N., Weaverdyck, N., Wechsler, R. H., Wu, W. L. K., Yanny, B., Yin, B., Zhang, Y., Zuntz, J., Abbott, T. M. C., Aguena, M., Allam, S., Annis, J., Bacon, D., Benson, B. A., Bertin, E., Bocquet, S., Brooks, D., Burke, D. L., Carlstrom, J. E., Carretero, J., Chang, C. L., Chown, R., Costanzi, M., da Costa, L. N., Crites, A. T., Pereira, M. E. S., de Haan, T., De Vicente, J., Desai, S., Diehl, H. T., Dobbs, M. A., Doel, P., Everett, W., Ferrero, I., Flaugher, B., Friedel, D., Frieman, J., García-Bellido, J., Gaztanaga, E., George, E. M., Giannantonio, T., Halverson, N. W., Hinton, S. R., Holder, G. P., Hollowood, D. L., Holzapfel, W. L., Honscheid, K., Hrubes, J. D., James, D. J., Knox, L., Kuehn, K., Lahav, O., Lee, A. T., Lima, M., Luong-Van, D., March, M., McMahon, J. J., Melchior, P., Menanteau, F., Meyer, S. S., Miquel, R., Mocanu, L., Mohr, J. J., Morgan, R., Natoli, T., Padin, S., Palmese, A., Paz-Chinchón, F., Pieres, A., Malagón, A. A. Plazas, Pryke, C., Reichardt, C. L., Romer, A. K., Ruhl, J. E., Sanchez, E., Schaffer, K. K., Schubnell, M., Serrano, S., Shirokoff, E., Smith, M., Staniszewski, Z., Stark, A. A., Suchyta, E., Tarle, G., Thomas, D., To, C., Vieira, J. D., Weller, J., and Williamson, R.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
Joint analyses of cross-correlations between measurements of galaxy positions, galaxy lensing, and lensing of the cosmic microwave background (CMB) offer powerful constraints on the large-scale structure of the Universe. In a forthcoming analysis, we will present cosmological constraints from the analysis of such cross-correlations measured using Year 3 data from the Dark Energy Survey (DES), and CMB data from the South Pole Telescope (SPT) and Planck. Here we present two key ingredients of this analysis: (1) an improved CMB lensing map in the SPT-SZ survey footprint, and (2) the analysis methodology that will be used to extract cosmological information from the cross-correlation measurements. Relative to previous lensing maps made from the same CMB observations, we have implemented techniques to remove contamination from the thermal Sunyaev Zel'dovich effect, enabling the extraction of cosmological information from smaller angular scales of the cross-correlation measurements than in previous analyses with DES Year 1 data. We describe our model for the cross-correlations between these maps and DES data, and validate our modeling choices to demonstrate the robustness of our analysis. We then forecast the expected cosmological constraints from the galaxy survey-CMB lensing auto and cross-correlations. We find that the galaxy-CMB lensing and galaxy shear-CMB lensing correlations will on their own provide a constraint on $S_8=\sigma_8 \sqrt{\Omega_{\rm m}/0.3}$ at the few percent level, providing a powerful consistency check for the DES-only constraints. We explore scenarios where external priors on shear calibration are removed, finding that the joint analysis of CMB lensing cross-correlations can provide constraints on the shear calibration amplitude at the 5 to 10% level., Comment: 30 pages, 20 figures, To be submitted to PRD
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- 2022
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181. Snowmass 2021 CMB-S4 White Paper
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Abazajian, Kevork, Abdulghafour, Arwa, Addison, Graeme E., Adshead, Peter, Ahmed, Zeeshan, Ajello, Marco, Akerib, Daniel, Allen, Steven W., Alonso, David, Alvarez, Marcelo, Amin, Mustafa A., Amiri, Mandana, Anderson, Adam, Ansarinejad, Behzad, Archipley, Melanie, Arnold, Kam S., Ashby, Matt, Aung, Han, Baccigalupi, Carlo, Baker, Carina, Bakshi, Abhishek, Bard, Debbie, Barkats, Denis, Barron, Darcy, Barry, Peter S., Bartlett, James G., Barton, Paul, Thakur, Ritoban Basu, Battaglia, Nicholas, Beall, Jim, Bean, Rachel, Beck, Dominic, Belkner, Sebastian, Benabed, Karim, Bender, Amy N., Benson, Bradford A., Besuner, Bobby, Bethermin, Matthieu, Bhimani, Sanah, Bianchini, Federico, Biquard, Simon, Birdwell, Ian, Bischoff, Colin A., Bleem, Lindsey, Bocaz, Paulina, Bock, James J., Bocquet, Sebastian, Boddy, Kimberly K., Bond, J. Richard, Borrill, Julian, Bouchet, Francois R., Brinckmann, Thejs, Brown, Michael L., Bryan, Sean, Buza, Victor, Byrum, Karen, Calabrese, Erminia, Calafut, Victoria, Caldwell, Robert, Carlstrom, John E., Carron, Julien, Cecil, Thomas, Challinor, Anthony, Chan, Victor, Chang, Clarence L., Chapman, Scott, Charles, Eric, Chauvin, Eric, Cheng, Cheng, Chesmore, Grace, Cheung, Kolen, Chinone, Yuji, Chluba, Jens, Cho, Hsiao-Mei Sherry, Choi, Steve, Clancy, Justin, Clark, Susan, Cooray, Asantha, Coppi, Gabriele, Corlett, John, Coulton, Will, Crawford, Thomas M., Crites, Abigail, Cukierman, Ari, Cyr-Racine, Francis-Yan, Dai, Wei-Ming, Daley, Cail, Dart, Eli, Daues, Gregorg, de Haan, Tijmen, Deaconu, Cosmin, Delabrouille, Jacques, Derylo, Greg, Devlin, Mark, Di Valentino, Eleonora, Dierickx, Marion, Dober, Brad, Doriese, Randy, Duff, Shannon, Dutcher, Daniel, Dvorkin, Cora, Dünner, Rolando, Eftekhari, Tarraneh, Eimer, Joseph, Bouhargani, Hamza El, Elleflot, Tucker, Emerson, Nick, Errard, Josquin, Essinger-Hileman, Thomas, Fabbian, Giulio, Fanfani, Valentina, Fasano, Alessandro, Feng, Chang, Ferraro, Simone, Filippini, Jeffrey P., Flauger, Raphael, Flaugher, Brenna, Fraisse, Aurelien A., Frisch, Josef, Frolov, Andrei, Galitzki, Nicholas, Gallardo, Patricio A., Galli, Silvia, Ganga, Ken, Gerbino, Martina, Giannakopoulos, Christos, Gilchriese, Murdock, Gluscevic, Vera, Goeckner-Wald, Neil, Goldfinger, David, Green, Daniel, Grimes, Paul, Grin, Daniel, Grohs, Evan, Gualtieri, Riccardo, Guarino, Vic, Gudmundsson, Jon E., Gullett, Ian, Guns, Sam, Habib, Salman, Haller, Gunther, Halpern, Mark, Halverson, Nils W., Hanany, Shaul, Hand, Emma, Harrington, Kathleen, Hasegawa, Masaya, Hasselfield, Matthew, Hazumi, Masashi, Heitmann, Katrin, Henderson, Shawn, Hensley, Brandon, Herbst, Ryan, Hervias-Caimapo, Carlos, Hill, J. Colin, Hills, Richard, Hivon, Eric, Hlozek, Renée, Ho, Anna, Holder, Gil, Hollister, Matt, Holzapfel, William, Hood, John, Hotinli, Selim, Hryciuk, Alec, Hubmayr, Johannes, Huffenberger, Kevin M., Hui, Howard, nez, Roberto Ibá, Ibitoye, Ayodeji, Ikape, Margaret, Irwin, Kent, Jacobus, Cooper, Jeong, Oliver, Johnson, Bradley R., Johnstone, Doug, Jones, William C., Joseph, John, Jost, Baptiste, Kang, Jae Hwan, Kaplan, Ari, Karkare, Kirit S., Katayama, Nobuhiko, Keskitalo, Reijo, King, Cesiley, Kisner, Theodore, Klein, Matthias, Knox, Lloyd, Koopman, Brian J., Kosowsky, Arthur, Kovac, John, Kovetz, Ely D., Krolewski, Alex, Kubik, Donna, Kuhlmann, Steve, Kuo, Chao-Lin, Kusaka, Akito, Lähteenmäki, Anne, Lau, Kenny, Lawrence, Charles R., Lee, Adrian T., Legrand, Louis, Leitner, Matthaeus, Leloup, Clément, Lewis, Antony, Li, Dale, Linder, Eric, Liodakis, Ioannis, Liu, Jia, Long, Kevin, Louis, Thibaut, Loverde, Marilena, Lowry, Lindsay, Lu, Chunyu, Lubin, Phil, Ma, Yin-Zhe, Maccarone, Thomas, Madhavacheril, Mathew S., Maldonado, Felipe, Mantz, Adam, Marques, Gabriela, Matsuda, Frederick, Mauskopf, Philip, May, Jared, McCarrick, Heather, McCracken, Ken, McMahon, Jeffrey, Meerburg, P. Daniel, Melin, Jean-Baptiste, Menanteau, Felipe, Meyers, Joel, Millea, Marius, Miranda, Vivian, Mitchell, Don, Mohr, Joseph, Moncelsi, Lorenzo, Monzani, Maria Elena, Moshed, Magdy, Mroczkowski, Tony, Mukherjee, Suvodip, Münchmeyer, Moritz, Nagai, Daisuke, Nagarajappa, Chandan, Nagy, Johanna, Namikawa, Toshiya, Nati, Federico, Natoli, Tyler, Nerval, Simran, Newburgh, Laura, Nguyen, Hogan, Nichols, Erik, Nicola, Andrina, Niemack, Michael D., Nord, Brian, Norton, Tim, Novosad, Valentine, O'Brient, Roger, Omori, Yuuki, Orlando, Giorgio, Osherson, Benjamin, Osten, Rachel, Padin, Stephen, Paine, Scott, Partridge, Bruce, Patil, Sanjaykumar, Petravick, Don, Petroff, Matthew, Pierpaoli, Elena, Pilleux, Mauricio, Pogosian, Levon, Prabhu, Karthik, Pryke, Clement, Puglisi, Giuseppe, Racine, Benjamin, Raghunathan, Srinivasan, Rahlin, Alexandra, Raveri, Marco, Reese, Ben, Reichardt, Christian L., Remazeilles, Mathieu, Rizzieri, Arianna, Rocha, Graca, Roe, Natalie A., Rotermund, Kaja, Roy, Anirban, Ruhl, John E., Saba, Joe, Sailer, Noah, Salatino, Maria, Saliwanchik, Benjamin, Sapozhnikov, Leonid, Rao, Mayuri Sathyanarayana, Saunders, Lauren, Schaan, Emmanuel, Schillaci, Alessandro, Schmitt, Benjamin, Scott, Douglas, Sehgal, Neelima, Shandera, Sarah, Sherwin, Blake D., Shirokoff, Erik, Shiu, Corwin, Simon, Sara M., Singari, Baibhav, Slosar, Anze, Spergel, David, Germaine, Tyler St., Staggs, Suzanne T., Stark, Antony A., Starkman, Glenn D., Steinbach, Bryan, Stompor, Radek, Stoughton, Chris, Suzuki, Aritoki, Tajima, Osamu, Tandoi, Chris, Teply, Grant P., Thayer, Gregg, Thompson, Keith, Thorne, Ben, Timbie, Peter, Tomasi, Maurizio, Trendafilova, Cynthia, Tristram, Matthieu, Tucker, Carole, Tucker, Gregory, Umiltà, Caterina, van Engelen, Alexander, van Marrewijk, Joshiwa, Vavagiakis, Eve M., Vergès, Clara, Vieira, Joaquin D., Vieregg, Abigail G., Wagoner, Kasey, Wallisch, Benjamin, Wang, Gensheng, Wang, Guo-Jian, Watson, Scott, Watts, Duncan, Weaver, Chris, Wenzl, Lukas, Westbrook, Ben, White, Martin, Whitehorn, Nathan, Wiedlea, Andrew, Williams, Paul, Wilson, Robert, Winch, Harrison, Wollack, Edward J., Wu, W. L. Kimmy, Xu, Zhilei, Yefremenko, Volodymyr G., Yu, Cyndia, Zegeye, David, Zivick, Jeff, and Zonca, Andrea
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Astrophysics - Cosmology and Nongalactic Astrophysics ,Astrophysics - Instrumentation and Methods for Astrophysics ,General Relativity and Quantum Cosmology ,High Energy Physics - Experiment ,High Energy Physics - Phenomenology - Abstract
This Snowmass 2021 White Paper describes the Cosmic Microwave Background Stage 4 project CMB-S4, which is designed to cross critical thresholds in our understanding of the origin and evolution of the Universe, from the highest energies at the dawn of time through the growth of structure to the present day. We provide an overview of the science case, the technical design, and project plan., Comment: Contribution to Snowmass 2021. arXiv admin note: substantial text overlap with arXiv:1908.01062, arXiv:1907.04473
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- 2022
182. Improved upper limit on degree-scale CMB B-mode polarization power from the 670 square-degree POLARBEAR survey
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The POLARBEAR Collaboration, Adachi, S., Adkins, T., Faúndez, M. A. O. Aguilar, Arnold, K. S., Baccigalupi, C., Barron, D., Chapman, S., Cheung, K., Chinone, Y., Crowley, K. T., Elleflot, T., Errard, J., Fabbian, G., Feng, C., Fujino, T., Galitzki, N., Halverson, N. W., Hasegawa, M., Hazumi, M., Hirose, H., Howe, L., Ito, J., Jeong, O., Kaneko, D., Katayama, N., Keating, B., Kisner, T., Krachmalnicoff, N., Kusaka, A., Lee, A. T., Linder, E., Lonappan, A. I., Lowry, L. N., Matsuda, F., Matsumura, T., Minami, Y., Murata, M., Nishino, H., Nishinomiya, Y., Poletti, D., Reichardt, C. L., Ross, C., Segawa, Y., Siritanasak, P., Stompor, R., Suzuki, A., Tajima, O., Takakura, S., Takatori, S., Tanabe, D., Teply, G., Yamada, K., and Zhou, Y.
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Astrophysics - Cosmology and Nongalactic Astrophysics ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
We report an improved measurement of the degree-scale cosmic microwave background $B$-mode angular-power spectrum over 670 square-degree sky area at 150 GHz with POLARBEAR. In the original analysis of the data, errors in the angle measurement of the continuously rotating half-wave plate, a polarization modulator, caused significant data loss. By introducing an angle-correction algorithm, the data volume is increased by a factor of 1.8. We report a new analysis using the larger data set. We find the measured $B$-mode spectrum is consistent with the $\Lambda$CDM model with Galactic dust foregrounds. We estimate the contamination of the foreground by cross-correlating our data and Planck 143, 217, and 353 GHz measurements, where its spectrum is modeled as a power law in angular scale and a modified blackbody in frequency. We place an upper limit on the tensor-to-scalar ratio $r$ < 0.33 at 95% confidence level after marginalizing over the foreground parameters., Comment: 16 pages, 9 figures, 8 tables, Published in ApJ
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- 2022
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183. Studies on Ni termination of a multilayer ceramic capacitor with high capacitance by using DC electrodeposition
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Lee, Wen-Hsi, Puteri, Narendra Gharini, Lee, Jason, and Lee, C. T.
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- 2023
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184. Application of a Multiplex Platform to Identify Novel Biomarkers for Pregnancy Location and Viability
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Lee, Iris T., Senapati, Suneeta, Schreiber, Courtney, Koelper, Nathanael, Takacs, Peter, and Barnhart, Kurt T.
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- 2023
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185. Changes in serial multiparametric MRI and FDG-PET/CT functional imaging during radiation therapy can predict treatment response in patients with head and neck cancer
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Trada, Yuvnik, Keall, Paul, Jameson, Michael, Moses, Daniel, Lin, Peter, Chlap, Phillip, Holloway, Lois, Min, Myo, Forstner, Dion, Fowler, Allan, and Lee, Mark T.
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- 2023
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186. A Cost–Utility Analysis of the Use of −125 mm Hg Closed-incision Negative Pressure Therapy in Oncoplastic Breast Surgery
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Bloom, Joshua A., Wareham, Carly, Chahine, Elsa, Singhal, Dhruv, Lin, Samuel J., Lee, Bernard T., Nardello, Salvatore, Homsy, Christopher, Persing, Sarah M., and Chatterjee, Abhishek
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- 2024
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187. The dynseq browser track shows context-specific features at nucleotide resolution
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Nair, Surag, Barrett, Arjun, Li, Daofeng, Raney, Brian J, Lee, Brian T, Kerpedjiev, Peter, Ramalingam, Vivekanandan, Pampari, Anusri, Lekschas, Fritz, Wang, Ting, Haeussler, Maximilian, and Kundaje, Anshul
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Biochemistry and Cell Biology ,Bioinformatics and Computational Biology ,Genetics ,Biological Sciences ,Biotechnology ,Human Genome ,Generic health relevance ,Nucleotides ,Software ,Databases ,Genetic ,Internet ,Web Browser ,Medical and Health Sciences ,Developmental Biology ,Agricultural biotechnology ,Bioinformatics and computational biology - Abstract
High-throughput experimental platforms have revolutionized the ability to profile biochemical and functional properties of biological sequences such as DNA, RNA and proteins. By collating several data modalities with customizable tracks rendered using intuitive visualizations, genome browsers enable an interactive and interpretable exploration of diverse types of genome profiling experiments and derived annotations. However, existing genome browser tracks are not well suited for intuitive visualization of high-resolution DNA sequence features such as transcription factor motifs. Typically, motif instances in regulatory DNA sequences are visualized as BED-based annotation tracks, which highlight the genomic coordinates of the motif instances but do not expose their specific sequences. Instead, a genome sequence track needs to be cross-referenced with the BED track to identify sequences of motif hits. Even so, quantitative information about the motif instances such as affinity or conservation as well as differences in base resolution from the consensus motif are not immediately apparent. This makes interpretation slow and challenging. This problem is compounded when analyzing several cellular states and/or molecular readouts (such as ATAC-seq and ChIP–seq) simultaneously, as coordinates of enriched regions (peaks) and the set of active transcription factor motifs vary across cell states.
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- 2022
188. Role of the Triplet State and Protein Dynamics in the Formation and Stability of the Tryptophan Radical in an Apoazurin Mutant
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López-Peña, Ignacio, Lee, Christopher T, Rivera, Joel J, and Kim, Judy E
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Chemical Sciences ,Physical Chemistry ,Theoretical and Computational Chemistry ,Apoproteins ,Azurin ,Kinetics ,Tryptophan ,Physical Sciences ,Engineering ,Chemical sciences ,Physical sciences - Abstract
The protein, azurin, has enabled the study of the tryptophan radical. Upon UV excitation of tyrosine-deficient apoazurin and in the presence of a Co(III) electron acceptor, the neutral radical (W48•) is formed. The lifetime of W48• in apoazurin is 41 s, which is shorter than the lifetime of several hours in Zn-substituted azurin. Molecular dynamics simulations revealed enhanced fluctuations of apoazurin which likely destabilize W48•. The photophysics of W48 was investigated to probe the precursor state for ET. The phosphorescence intensity was eliminated in the presence of an electron acceptor while the fluorescence was unchanged; this quenching of the phosphorescence is attributed to ET. The kinetics associated with W48• were examined with a model that incorporates intersystem crossing, ET, deprotonation, and decay of the cation radical. The estimated rate constants for ET (6 × 106 s-1) and deprotonation (3 × 105 s-1) are in agreement with a photoinduced mechanism where W48• is derived from the triplet state. The triplet as the precursor state for ET was supported by photolysis of apoazurin with 280 nm in the absence and presence of triplet-absorbing 405 nm light. Absorption bands from the neutral radical were observed only in the presence of blue light.
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- 2022
189. Mem3DG: Modeling membrane mechanochemical dynamics in 3D using discrete differential geometry.
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Zhu, Cuncheng, Lee, Christopher T, and Rangamani, Padmini
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Bioengineering ,Generic health relevance - Abstract
Biomembranes adopt varying morphologies that are vital to cellular functions. Many studies use computational modeling to understand how various mechanochemical factors contribute to membrane shape transformations. Compared with approximation-based methods (e.g., finite element method [FEM]), the class of discrete mesh models offers greater flexibility to simulate complex physics and shapes in three dimensions; its formulation produces an efficient algorithm while maintaining coordinate-free geometric descriptions. However, ambiguities in geometric definitions in the discrete context have led to a lack of consensus on which discrete mesh model is theoretically and numerically optimal; a bijective relationship between the terms contributing to both the energy and forces from the discrete and smooth geometric theories remains to be established. We address this and present an extensible framework, Mem3DG, for modeling 3D mechanochemical dynamics of membranes based on discrete differential geometry (DDG) on triangulated meshes. The formalism of DDG resolves the inconsistency and provides a unifying perspective on how to relate the smooth and discrete energy and forces. To demonstrate, Mem3DG is used to model a sequence of examples with increasing mechanochemical complexity: recovering classical shape transformations such as 1) biconcave disk, dumbbell, and unduloid; and 2) spherical bud on spherical, flat-patch membrane; investigating how the coupling of membrane mechanics with protein mobility jointly affects phase and shape transformation. As high-resolution 3D imaging of membrane ultrastructure becomes more readily available, we envision Mem3DG to be applied as an end-to-end tool to simulate realistic cell geometry under user-specified mechanochemical conditions.
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- 2022
190. Probing Cosmic Inflation with the LiteBIRD Cosmic Microwave Background Polarization Survey
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LiteBIRD Collaboration, Allys, E., Arnold, K., Aumont, J., Aurlien, R., Azzoni, S., Baccigalupi, C., Banday, A. J., Banerji, R., Barreiro, R. B., Bartolo, N., Bautista, L., Beck, D., Beckman, S., Bersanelli, M., Boulanger, F., Brilenkov, M., Bucher, M., Calabrese, E., Campeti, P., Carones, A., Casas, F. J., Catalano, A., Chan, V., Cheung, K., Chinone, Y., Clark, S. E., Columbro, F., D'Alessandro, G., de Bernardis, P., de Haan, T., de la Hoz, E., De Petris, M., Della Torre, S., Diego-Palazuelos, P., Dobbs, M., Dotani, T., Duval, J. M., Elleflot, T., Eriksen, H. K., Errard, J., Essinger-Hileman, T., Finelli, F., Flauger, R., Franceschet, C., Fuskeland, U., Galloway, M., Ganga, K., Gerbino, M., Gervasi, M., Génova-Santos, R. T., Ghigna, T., Giardiello, S., Gjerløw, E., Grain, J., Grupp, F., Gruppuso, A., Gudmundsson, J. E., Halverson, N. W., Hargrave, P., Hasebe, T., Hasegawa, M., Hazumi, M., Henrot-Versillé, S., Hensley, B., Hergt, L. T., Herman, D., Hivon, E., Hlozek, R. A., Hornsby, A. L., Hoshino, Y., Hubmayr, J., Ichiki, K., Iida, T., Imada, H., Ishino, H., Jaehnig, G., Katayama, N., Kato, A., Keskitalo, R., Kisner, T., Kobayashi, Y., Kogut, A., Kohri, K., Komatsu, E., Komatsu, K., Konishi, K., Krachmalnicoff, N., Kuo, C. L., Lamagna, L., Lattanzi, M., Lee, A. T., Leloup, C., Levrier, F., Linder, E., Luzzi, G., Macias-Perez, J., Maciaszek, T., Maffei, B., Maino, D., Mandelli, S., Martínez-González, E., Masi, S., Massa, M., Matarrese, S., Matsuda, F. T., Matsumura, T., Mele, L., Migliaccio, M., Minami, Y., Moggi, A., Montgomery, J., Montier, L., Morgante, G., Mot, B., Nagano, Y., Nagasaki, T., Nagata, R., Nakano, R., Namikawa, T., Nati, F., Natoli, P., Nerval, S., Noviello, F., Odagiri, K., Oguri, S., Ohsaki, H., Pagano, L., Paiella, A., Paoletti, D., Passerini, A., Patanchon, G., Piacentini, F., Piat, M., Pisano, G., Polenta, G., Poletti, D., Prouvé, T., Puglisi, G., Rambaud, D., Raum, C., Realini, S., Reinecke, M., Remazeilles, M., Ritacco, A., Roudil, G., Rubino-Martin, J. A., Russell, M., Sakurai, H., Sakurai, Y., Sasaki, M., Scott, D., Sekimoto, Y., Shinozaki, K., Shiraishi, M., Shirron, P., Signorelli, G., Spinella, F., Stever, S., Stompor, R., Sugiyama, S., Sullivan, R. M., Suzuki, A., Svalheim, T. L., Switzer, E., Takaku, R., Takakura, H., Takase, Y., Tartari, A., Terao, Y., Thermeau, J., Thommesen, H., Thompson, K. L., Tomasi, M., Tominaga, M., Tristram, M., Tsuji, M., Tsujimoto, M., Vacher, L., Vielva, P., Vittorio, N., Wang, W., Watanuki, K., Wehus, I. K., Weller, J., Westbrook, B., Wilms, J., Winter, B., Wollack, E. J., Yumoto, J., and Zannoni, M.
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
LiteBIRD, the Lite (Light) satellite for the study of B-mode polarization and Inflation from cosmic background Radiation Detection, is a space mission for primordial cosmology and fundamental physics. The Japan Aerospace Exploration Agency (JAXA) selected LiteBIRD in May 2019 as a strategic large-class (L-class) mission, with an expected launch in the late 2020s using JAXA's H3 rocket. LiteBIRD is planned to orbit the Sun-Earth Lagrangian point L2, where it will map the cosmic microwave background (CMB) polarization over the entire sky for three years, with three telescopes in 15 frequency bands between 34 and 448 GHz, to achieve an unprecedented total sensitivity of 2.2$\mu$K-arcmin, with a typical angular resolution of 0.5$^\circ$ at 100 GHz. The primary scientific objective of LiteBIRD is to search for the signal from cosmic inflation, either making a discovery or ruling out well-motivated inflationary models. The measurements of LiteBIRD will also provide us with insight into the quantum nature of gravity and other new physics beyond the standard models of particle physics and cosmology. We provide an overview of the LiteBIRD project, including scientific objectives, mission and system requirements, operation concept, spacecraft and payload module design, expected scientific outcomes, potential design extensions and synergies with other projects., Comment: 155 pages, accepted for publication in PTEP
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- 2022
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191. Asteroid Measurements at Millimeter Wavelengths with the South Pole Telescope
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Chichura, P. M., Foster, A., Patel, C., Ossa-Jaen, N., Ade, P. A. R., Ahmed, Z., Anderson, A. J., Archipley, M., Austermann, J. E., Avva, J. S., Balkenhol, L., Barry, P. S., Thakur, R. Basu, Beall, J. A., Benabed, K., Bender, A. N., Benson, B. A., Bianchini, F., Bleem, L. E., Bouchet, F. R., Bryant, L., Byrum, K., Carlstrom, J. E., Carter, F. W., Cecil, T. W., Chang, C. L., Chaubal, P., Chen, G., Chiang, H. C., Cho, H. -M., Chou, T-L., Citron, R., Cliche, J. -F., Crawford, T. M., Crites, A. T., Cukierman, A., Daley, C. M., Denison, E. V., Dibert, K., Ding, J., Dobbs, M. A., Dutcher, D., Everett, W., Feng, C., Ferguson, K. R., Fu, J., Galli, S., Gallicchio, J., Gambrel, A. E., Gardner, R. W., George, E. M., Goeckner-Wald, N., Gualtieri, R., Guns, S., Gupta, N., Guyser, R., de Haan, T., Halverson, N. W., Harke-Hosemann, A. H., Harrington, N. L., Henning, J. W., Hilton, G. C., Hivon, E., Holder, G. P., Holzapfel, W. L., Hood, J. C., Howe, D., Hrubes, J. D., Huang, N., Hubmayr, J., Irwin, K. D., Jeong, O. B., Jonas, M., Jones, A., Khaire, T. S., Knox, L., Kofman, A. M., Korman, M., Kubik, D. L., Kuhlmann, S., Kuo, C. -L., Lee, A. T., Leitch, E. M., Li, D., Lowitz, A., Lu, C., Marrone, D. P., McMahon, J. J., Meyer, S. S., Michalik, D., Millea, M., Mocanu, L. M., Montgomery, J., Moran, C. Corbett, Nadolski, A., Natoli, T., Nguyen, H., Nibarger, J. P., Noble, G., Novosad, V., Omori, Y., Padin, S., Pan, Z., Paschos, P., Patil, S., Pearson, J., Phadke, K. A., Posada, C. M., Prabhu, K., Pryke, C., Quan, W., Rahlin, A., Reichardt, C. L., Riebel, D., Riedel, B., Rouble, M., Ruhl, J. E., Saliwanchik, B. R., Sayre, J. T., Schaffer, K. K., Schiappucci, E., Shirokoff, E., Sievers, C., Smecher, G., Sobrin, J. A., Springmann, A., Stark, A. A., Stephen, J., Story, K. T., Suzuki, A., Tandoi, C., Thompson, K. L., Thorne, B., Tucker, C., Umilta, C., Vale, L. R., Veach, T., Vieira, J. D., Wang, G., Whitehorn, N., Wu, W. L. K., Yefremenko, V., Yoon, K. W., and Young, M. R.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
We present the first measurements of asteroids in millimeter wavelength (mm) data from the South Pole Telescope (SPT), which is used primarily to study the cosmic microwave background (CMB). We analyze maps of two $\sim270$ deg$^2$ sky regions near the ecliptic plane, each observed with the SPTpol camera $\sim100$ times over one month. We subtract the mean of all maps of a given field, removing static sky signal, and then average the mean-subtracted maps at known asteroid locations. We detect three asteroids$\text{ -- }$(324) Bamberga, (13) Egeria, and (22) Kalliope$\text{ -- }$with signal-to-noise ratios (S/N) of 11.2, 10.4, and 6.1, respectively, at 2.0 mm (150 GHz); we also detect (324) Bamberga with S/N of 4.1 at 3.2 mm (95 GHz). We place constraints on these asteroids' effective emissivities, brightness temperatures, and light curve modulation amplitude. Our flux density measurements of (324) Bamberga and (13) Egeria roughly agree with predictions, while our measurements of (22) Kalliope suggest lower flux, corresponding to effective emissivities of $0.66 \pm 0.11$ at 2.0 mm and $<0.47$ at 3.2mm. We predict the asteroids detectable in other SPT datasets and find good agreement with detections of (772) Tanete and (1093) Freda in recent data from the SPT-3G camera, which has $\sim10 \times$ the mapping speed of SPTpol. This work is the first focused analysis of asteroids in data from CMB surveys, and it demonstrates we can repurpose historic and future datasets for asteroid studies. Future SPT measurements can help constrain the distribution of surface properties over a larger asteroid population., Comment: 21 pages, 9 figures
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- 2022
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192. A DFS Algorithm for Maximum Matchings in General Graphs
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Lee, Tony T., Lu, Bojun, and Chu, Hanli
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Computer Science - Data Structures and Algorithms ,05C30 (Primary) 68R10, 68R05 (Secondary) ,G.2.1 ,G.2.2 ,F.2.2 - Abstract
In this paper, we propose a depth-first search (DFS) algorithm for searching maximum matchings in general graphs. Unlike blossom shrinking algorithms, which store all possible alternative alternating paths in the super-vertices shrunk from blossoms, the newly proposed algorithm does not involve blossom shrinking. The basic idea is to deflect the alternating path when facing blossoms. The algorithm maintains detour information in an auxiliary stack to minimize the redundant data structures. A benefit of our technique is to avoid spending time on shrinking and expanding blossoms. This DFS algorithm can determine a maximum matching of a general graph with $m$ edges and $n$ vertices in $O(mn)$ time with space complexity $O(n)$., Comment: 17 pages, 9 figures, 2 tables
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- 2022
193. Magnetic fields in the formation of the first stars.--II Results
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Stacy, Athena, McKee, Christopher F., Lee, Aaron T., Klein, Richard I., and Li, Pak Shing
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
Beginning with cosmological initial conditions at z=100, we simulate the effects of magnetic fields on the formation of Population III stars and compare our results with the predictions of Paper I. We use Gadget-2 to follow the evolution of the system while the field is weak. We introduce a new method for treating kinematic fields by tracking the evolution of the deformation tensor. The growth rate in this stage of the simulation is lower than expected for diffuse astrophysical plasmas, which have a very low resistivity (high magnetic Prandtl number); we attribute this to the large numerical resistivity in simulations, corresponding to a magnetic Prandtl number of order unity. When the magnetic field begins to be dynamically significant in the core of the minihalo at z=27, we map it onto a uniform grid and follow the evolution in an adaptive mesh refinement, MHD simulation in Orion2. The nonlinear evolution of the field in the Orion2 simulation violates flux-freezing and is consistent with the theory proposed by Xu & Lazarian. The fields approach equipartition with kinetic energy at densities ~ 10^10 - 10^12 cm^-3. When the same calculation is carried out in Orion2 with no magnetic fields, several protostars form, ranging in mass from ~ 1 to 30 M_sol with magnetic fields, only a single ~ 30 M_sol protostar forms by the end of the simulation. Magnetic fields thus suppress the formation of low-mass Pop III stars, yielding a top-heavy Pop III IMF and contributing to the absence of observed Pop III stars., Comment: 31 pages, 30 figures, accepted to MNRAS
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- 2022
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194. Combining Planck and SPT cluster catalogs: cosmological analysis and impact on Planck scaling relation calibration
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Salvati, L., Saro, A., Bocquet, S., Costanzi, M., Ansarinejad, B., Benson, B. A., Bleem, L. E., Calzadilla, M. S., Carlstrom, J. E., Chang, C. L., Chown, R., Crites, A. T., deHaan, T., Dobbs, M. A., Everett, W. B., Floyd, B., Grandis, S., George, E. M., Halverson, N. W., Holder, G. P., Holzapfel, W. L., Hrubes, J. D., Lee, A. T., Luong-Van, D., McDonald, M., McMahon, J. J., Meyer, S. S., Millea, M., Mocanu, L. M., Mohr, J. J., Natoli, T., Omori, Y., Padin, S., Pryke, C., Reichardt, C. L., Ruhl, J. E., Ruppin, F., Schaffer, K. K., Schrabback, T., Shirokoff, E., Staniszewski, Z., Stark, A. A., Vieira, J. D., and Williamson, R.
- Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We provide the first combined cosmological analysis of South Pole Telescope (SPT) and Planck cluster catalogs. The aim is to provide an independent calibration for Planck scaling relations, exploiting the cosmological constraining power of the SPT-SZ cluster catalog and its dedicated weak lensing (WL) and X-ray follow-up observations. We build a new version of the Planck cluster likelihood. In the $\nu \Lambda$CDM scenario, focusing on the mass slope and mass bias of Planck scaling relations, we find $\alpha_{\text{SZ}} = 1.49_{-0.10}^{+0.07}$ and $(1-b)_{\text{SZ}} = 0.69_{-0.14}^{+0.07}$ respectively. The results for the mass slope show a $\sim 4 \, \sigma$ departure from the self-similar evolution, $\alpha_{\text{SZ}} \sim 1.8$. This shift is mainly driven by the matter density value preferred by SPT data, $\Omega_m = 0.30 \pm 0.03$, lower than the one obtained by Planck data alone, $\Omega_m = 0.37_{-0.06}^{+0.02}$. The mass bias constraints are consistent both with outcomes of hydrodynamical simulations and external WL calibrations, $(1-b) \sim 0.8$, and with results required by the Planck cosmic microwave background cosmology, $(1-b) \sim 0.6$. From this analysis, we obtain a new catalog of Planck cluster masses $M_{500}$. We estimate the ratio between the published Planck $M_{\text{SZ}}$ masses and our derived masses $M_{500}$, as a "measured mass bias", $(1-b)_M$. We analyse the mass, redshift and detection noise dependence of $(1-b)_M$, finding an increasing trend towards high redshift and low mass. These results mimic the effect of departure from self-similarity in cluster evolution, showing different dependencies for the low-mass high-mass, low-z high-z regimes., Comment: 22 pages, 10 figures, the catalogs can be found at http://pole.uchicago.edu/public/data/sptplanck_cluster
- Published
- 2021
- Full Text
- View/download PDF
195. Low Noise Frequency Domain Multiplexing of TES Bolometers using Sub-kelvin SQUIDs
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Elleflot, Tucker, Suzuki, Aritoki, Arnold, Kam, Bebek, Chris, Cantor, Robin H., Crowley, Kevin T., Groh, John, de Haan, Tijmen, Hornsby, Amber, Joseph, John, Lee, Adrian T., Liu, Tiffany, Montgomery, Joshua, Russell, Megan, and Yu, Qingyang
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Physics - Instrumentation and Detectors ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
Digital Frequency-Domain Multiplexing (DfMux) is a technique that uses MHz superconducting resonators and Superconducting Quantum Interference Device (SQUID) arrays to read out sets of Transition Edge Sensors. DfMux has been used by several Cosmic Microwave Background experiments, including most recently POLARBEAR-2 and SPT-3G with multiplexing factors as high as 68, and is the baseline readout technology for the planned satellite mission LiteBIRD. Here, we present recent work focused on improving DfMux readout noise, reducing parasitic impedance, and improving sensor operation. We have achieved a substantial reduction in stray impedance by integrating the sensors, resonators, and SQUID array onto a single carrier board operated at 250 mK. This also drastically simplifies the packaging of the cryogenic components and leads to better-controlled crosstalk. We demonstrate a low readout noise level of 8.6 pA/Hz$^{-1/2}$, which was made possible by operating the SQUID array at a reduced temperature and with a low dynamic impedance. This is a factor of two improvement compared to the achieved readout noise level in currently operating Cosmic Microwave Background experiments using DfMux and represents a critical step toward maturation of the technology for the next generation of instruments.
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- 2021
- Full Text
- View/download PDF
196. Fundamental Technical Skills of Endovascular Surgery: A Preliminary Study on Its Impact on Skills and Stress during Procedures
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Paris, Hélène, Mertes, Paul-Michel, Rigberg, David, Shames, Murray L., Sheahan, Malachi, Lee, Jason T., Mitchell, Erica L., Eidt, John F., Rouby, Anne-Florence, Neumann, Nicole, Vento, Vincenzo, Lejay, Anne, Kuntz, Salomé, Bourcier, Tristan, Oulehri, Walid, Bismuth, Jean, and Chakfé, Nabil
- Published
- 2024
- Full Text
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197. Association of Race and Postoperative Outcomes in Ventral Hernia Repair With Component Separation
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Hernandez Alvarez, Angelica, Foppiani, Jose, Foster, Lacey, Kim, Erin J., Schuster, Kirsten, Lee, Daniela, Escobar-Domingo, Maria J., Taritsa, Iulianna, Lin, Samuel J., and Lee, Bernard T.
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- 2024
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198. Community Collaboration to Advance Racial/Ethnic Equity in Colorectal Cancer Screening: Protocol for a Multilevel Intervention to Improve Screening and Follow-up in Community Health Centers
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May, Folasade P., Brodney, Suzanne, Tuan, Jessica J., Syngal, Sapna, Chan, Andrew T., Glenn, Beth, Johnson, Gina, Chang, Yuchiao, Drew, David A., Moy, Beverly, Rodriguez, Nicolette J., Warner, Erica T., Anyane-Yeboa, Adjoa, Ukaegbu, Chinedu, Davis, Anjelica Q., Schoolcraft, Kimberly, Regan, Susan, Yoguez, Nathan, Kuney, Samantha, Le Beaux, Kelley, Jeffries, Catherine, Lee, Ellen T., Bhat, Roopa, and Haas, Jennifer S.
- Published
- 2024
- Full Text
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199. Beyond the language barrier: Assessing health literacy of Spanish breast cancer surgery resources
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Hernandez Alvarez, Angelica, Escobar-Domingo, Maria J., Lee, Daniela, Schuster, Kirsten, Foppiani, Jose, Taritsa, Iulianna, Lin, Samuel J., and Lee, Bernard T.
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- 2024
- Full Text
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200. Breast Reduction Epidemiology and Complications in Nonbinary, Transgender, and Cisgender Adults
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Miller, Amitai S., Escobar-Domingo, Maria J., Lee, Bernard T., Ganor, Oren, Lin, Samuel J., Hu, Sophia, Pusic, Andrea L., and Kaur, Manraj N.
- Published
- 2024
- Full Text
- View/download PDF
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