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Background: Nicotine pouches containing synthetic nicotine or tobacco-derived nicotine (TDN) are available in the United States. Synthetic nicotine pouches are often marketed as "tobacco-free nicotine" (TFN), which may alter risk perceptions and product appeal. This study examined young adults' perceptions of TFN versus TDN pouches and the associations between product perceptions and TFN pouch awareness, susceptibility, and use, respectively.Aims and Methods: In total 630 young adults (18-25 years) completed an online Qualtrics panels survey in 2021. Participants were informed that TFN pouches contain synthetic nicotine as opposed to TDN. Participants reported on comparative risk perceptions for TFN versus TDN pouches and on TFN pouch awareness, susceptibility, and use. Unadjusted between-group comparisons and adjusted binary logistic regressions were run to examine relationships between product perceptions and TFN pouch awareness, susceptibility, and use.Results: Participants were aware of (37.3%), susceptible to (29.2%), or had used TFN pouches (3.8%). In unadjusted comparisons, TFN pouch awareness, susceptibility, and use were associated with disproportionately perceiving TFN pouches as less harmful or otherwise better than TDN pouches. In adjusted models, relationships between favorable perceptions and both TFN pouch awareness and susceptibility remained significant.Conclusions: The descriptor "tobacco-free" may impact risk perceptions and the appeal of nicotine pouches among young adults. While no direct relationship was observed between TFN perceptions and TFN pouch use in the adjusted model, perceptions remained related to product awareness and susceptibility, which may be linked to future use. Continued surveillance is needed to fully determine how the term "tobacco-free" on product packaging and advertising impacts longitudinal public health outcomes.Implications: Nicotine pouches originally contained TDN. Today, numerous brands of synthetic nicotine pouches, which are often marketed as "tobacco-free," are available on the market. We informed participants that "tobacco-free nicotine" pouches contain synthetic nicotine and examined comparative risk perceptions (i.e. tobacco-free vs. TDN pouches) and TFN pouch awareness, susceptibility, and use. Perceiving tobacco-free nicotine pouches as less harmful than tobacco-derived pouches was associated with product awareness, susceptibility, and use in unadjusted models and with awareness and susceptibility in adjusted models. Restricting the term "tobacco-free" may become necessary if the term inaccurately reduces product risk perceptions or increases product appeal. [ABSTRACT FROM AUTHOR]

Introduction Patient Reported Outcome Measures (PROMs) are frequently recommended as a clinical strategy, tracking health-related quality of life (HRQOL) indicating symptom burden and treatment tolerance. The PLANET QOL App was launched in 2018 to sit alongside the national PLANET NET Registry. This App tracks PROMs including BMI, ECOG, Bowel symptoms and HRQOL (EORTC QLQ30, GINET21). Peter MacCallum Cancer Centre recently implemented a Nurse Led Clinic (NLC) for patients with NETs (Neuroendocrine Tumours), utilising the PLANET QOL App. Aim To pilot the utilisation of an electronic PROM in the NET NLC. Methodology A NLC model was piloted over three phases: planning, implementation, and evaluation. Eligible patients included those with low/intermediate grade NETs. NLC frequency was determined with supervising Medical Oncologist with medical review at least annually and escalation policies and pathways were established (e.g., symptom escalation, other clinical concerns). New NLC participants were encouraged to download the App, with PROMs to be reported monthly. These data formed the basis of the NLC assessment, with subsequent interventions as appropriate. For patients unable to use the app, a similarly structured assessment was conducted verbally. Results 71 NLC consultations were conducted over six months (18 in person and 53 via telehealth). Of these, five individuals utilised the PLANET QOL App, which was a useful tool in assessing symptoms and overall wellbeing. The main factor in App non-usage was technological (e.g., elderly), those not wanting to be reminded of their disease, and language limitations. Use of the PROM was also hampered by the lack of integration between the PLANET database (designed primarily as a research tool) and patient hospital electronic medical records. Conclusion The use of electronic PROMS in the NET NLC has enabled meaningful inclusion of this data in clinical care. Next steps will include addressing technical challenges, optimising data visualisation, and integration of viewing systems. [ABSTRACT FROM AUTHOR]

Introduction: Assessing youth vaping expectancies using a psychometrically sound measure can improve understanding of e-cigarette susceptibility and use.Aims and Methods: We evaluated the psychometric properties of the Short-Form Vaping Consequences Questionnaire (SF-VCQ), an expectancy measure previously validated with adults, within a sample of 1753 high school adolescents who completed an online, school-based survey in Fall 2020 (51.6% female; 15.56 [1.22] years old; 46.6% non-Hispanic white; 26.9% reported lifetime but no past-30-day vaping; 12.6% reported past-30-day vaping). Analyses included confirmatory factor analysis, internal consistency, measurement invariance, between-group differences, and test-criterion relationships.Results: The four-factor structure was confirmed and was scalar invariant by lifetime and past-month vaping status, sex, and race. All subscales were internally reliable (mean α = 0.94). The subscales were sensitive to differences based on sex, race, vaping susceptibility among never users, and lifetime and past-month vaping status. For example, students who vaped in the past-month held weaker expectancies for negative consequences but stronger expectancies for positive reinforcement, negative reinforcement, and appetite/weight control compared to lifetime vapers. Unadjusted relationships within the subsamples of lifetime and past-month vapers provided evidence of convergent validity. Evidence for concurrent validity was observed for all samples after accounting for covariates. For example, expectancies for positive reinforcement, negative reinforcement, and appetite/weight control remained significantly associated with past-month vaping frequency.Conclusions: The SF-VCQ evidenced excellent internal reliability, scalar measurement invariance, and construct, convergent, and concurrent validity in samples of never, lifetime, and past-month adolescent e-cigarette users. Findings support using the SF-VCQ for assessing youths' vaping-related expectancies.Implications: The current study established the psychometric properties of the SF-VCQ for use among adolescents with and without vaping experience, including measurement invariance that permits direct comparisons of expectancies across these two groups. When considered in concert with previously published research in adults, the SF-VCQ provides researchers with a measure that can be used with both youth and adult samples. Observed relationships between positive expectancies and vaping susceptibility in vaping naïve youth and indices of vaping frequency in youth with vaping experience suggest that challenging positive expectancies may be a valuable addition to prevention and intervention efforts to reduce youth vaping. [ABSTRACT FROM AUTHOR]