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1,117 results on '"Koivikko, A."'

151. Macroalgal communities face the challenge of changing biotic interactions: Review with focus on the Baltic Sea

Author

Korpinen, Samuli, Honkanen, Tuija, Hemmi, Anne, Koivikko, Rlltta, Veskoski, Outi, Loponen, Jyrki, and Jormalanen, Veijo

Subjects
Baltic Sea -- Environmental aspects, Eutrophication -- Environmental aspects, Eutrophication -- Research, Water bloom -- Research, Marine microbiology -- Research, Environmental issues
Abstract

Studies to analyze and examine the effects of eutrophication on the modification of the biotic interactions in the littoral macroalgal communities in the Baltic Sea were conducted. The analysis reveals that the biotic interactions, instead of remaining fixed keep evolving, which also reveals that the potential of plants and grazers to adapt is very crucial for their survival in the changing environment.

Published
2007

152. Activity, selectivity, and stability of vanadium catalysts in formaldehyde production from emissionsof volatile organic compounds

Author

Laitinen, T. (Tiina), Ojala, S. (Satu), Cousin, R. (Renaud), Koivikko, N. (Niina), Poupin, C. (Christophe), El Assal, Z. (Zouhair), Aho, A. (Atte), Keiski, R. L. (Riitta L.), Laitinen, T. (Tiina), Ojala, S. (Satu), Cousin, R. (Renaud), Koivikko, N. (Niina), Poupin, C. (Christophe), El Assal, Z. (Zouhair), Aho, A. (Atte), and Keiski, R. L. (Riitta L.)

Abstract

In this study, activity, selectivity and stability of vanadium catalysts supported on zirconia, hafnia, and alumina were examined in the oxidation of methanethiol and methanol to formaldehyde. The 3 wt-% vanadia–alumina catalyst with low VOx surface density showed the highest activity in the formaldehyde production. However, during the stability test, this catalyst deactivated due to the change in the oxidation state of vanadium from V5+ to V4+, decrease the amount of surface vanadium species and the formation of sulphates on the material surface. Zirconia and hafnia supported catalysts with high VOx surface density demonstrated better stability in the reaction conditions, but their activity in the formaldehyde production was lower. One reason for the lower activity might be the formation of metal-mixed oxide phases between vanadia and the support, which could also explain the decreased sulphur deposition on zirconia and hafnia after vanadium impregnation.

Published
2020

164. Admission Levels of Interleukin 10 and Amyloid β 1–40 Improve the Outcome Prediction Performance of the Helsinki Computed Tomography Score in Traumatic Brain Injury

Author

Posti, Jussi P., primary, Takala, Riikka S. K., additional, Raj, Rahul, additional, Luoto, Teemu M., additional, Azurmendi, Leire, additional, Lagerstedt, Linnéa, additional, Mohammadian, Mehrbod, additional, Hossain, Iftakher, additional, Gill, Jessica, additional, Frantzén, Janek, additional, van Gils, Mark, additional, Hutchinson, Peter J., additional, Katila, Ari J., additional, Koivikko, Pia, additional, Maanpää, Henna-Riikka, additional, Menon, David K., additional, Newcombe, Virginia F., additional, Tallus, Jussi, additional, Blennow, Kaj, additional, Tenovuo, Olli, additional, Zetterberg, Henrik, additional, and Sanchez, Jean-Charles, additional

Published
2020
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169. Effect of hydrolyzed infant formula vs conventional formula on risk of type 1 diabetes the TRIGR randomized clinical trial

Author

Knip M., Akerblom H. K., Altaji E., Becker D., Bruining J., Castano L., Danne T., De Beaufort C., Dosch H. -M., Dupre J., Fraser W. D., Howard N., Ilonen J., Konrad D., Kordonouri O., Krischer J. P., Lawson M. L., Ludvigsson J., Madacsy L., Mahon J. L., Ormisson A., Palmer J. P., Pozzilli P., Savilahti E., Serrano-Rios M., Songini M., Taback S., Vaarala O., White N. H., Virtanen S. M., Wasikowa R., Mandrup-Poulsen T., Arjas E., Lernmark A., Laara E., Schmidt B., Hyytinen M., Koski K., Koski M., Merentie K., Pajakkala E., Reunanen A., Salonen M., Terhonen T., Virkkunen S., Cuthbertson D., Gainer B., Hadley D., Malloy J., Nallamshetty L., Shanker L., Bradley B., Lough G., Fraser W., Sermer M., Taback S. P., Franciscus M., Nucci A., Palmer J., Alahuhta K., Barlund S., Korhonen T., Kovanen L., Lehtonen E., Niinisto S., Pekkala M., Sorkio S., Toivanen L., Vahatalo L., Uusitalo U., Ohman T., Bongiorno R., Catteau J., Fraser G., Lloyd M., Crock P., Giles M., Siech K., See D. W., Brown C., Craig M., Johnston A., Bere L. J., Clarson C. L., Jenner M., McManus R., Renato N., Lovell M., Higo D., Kent N., Kwan J., Marshall C., Metzger D., Chanoine J. -P., Stewart L., Thompson D., Edwards A., Lange I., Mercer J., Pacaud D., Josephine H., Schwarz W., Stephure D. K., Boer J., Chatur T., Chick C., Couch B., Demianczuk N., Girgis R., Marks S., Ryan E., Thompson M., Dean H. J., Grant L., Hamelin K., LaForte J., Murphy L., Catte D., Schneider C., Sellers E. A. C., Woo V., Boland A., Clark H. D., Cooper T., Gruslin A., Karovitch A., Keely E., Malcolm J. C., Sauro V., Tawagi G. F., Andrighetti S., Arnold G., Barrett J., Blumer I., Daneman D., Donat D., Ehrlich R., Feig D., Gottesman I., Gysler M., Karkanis S., Kenshole A., Knight B., Lackie E., Lewis V., Martin M. J., Maxwell C., Oliver G., Panchum P., Shilletto N., Simone A., Skidmore M., Turrini T., Wong S., Allen C., Belanger L., Bouchard I., Ferland S., Frenette L., Garrido-Russo M., Leblanc M., Imbeault J., Morin V., Olivier G., Weisnagell J., Costain G., Dornan J., Heath K., MacSween M. -C., McGibbon A., Ramsay C., Sanderson F., Sanderson S., Benabdesselam L., Gonthier M., Huot C., Thibeault M., Laforte D., Legault L., Perron P., Armson A., Canning P., Cummings E. A., Ivanko V., McLeod L., Mokashi A., Scott K., Bridger T., Crane J., Crummell C., Curtis J. C., Dawson C., Joyce C., Newhook L. A., Newman S., Druken E., Begum-Hasan J., Breen A., Houlden R., Woods M., Carrson G., Kelly S., Martel M. J., Penner M., Sankaran K., Hardy-Brown K., King N., White R. A., Park M., Popkin J., Robson L., Coles K., Al Taji E., Cerna M., Cerny M., Francova H., Hainerova I., Kothankova H., Koukalova R., Krakorova V., Mendlova P., Sitova R., Stechova K., Vavrinec J., Vosahlo J., Zlatohlavkova B., Brazdova L., Faksova P., Gregorova D., Kantor L., Malkova K., Venhacova J., Venhacova P., Cipra A., Skvor J., Budejovice C., Tomsikova Z., Botkova-Krauseova H., Mockova A., Paterova P., Gogelova P., Kandrnalova J., Einberg U., Jakovlev U., Posiadlo S., Rannaste E., Raukas R., Riikjarv M. -A., Valla K., Astover V., Kirss A., Retpap J., Taht E., Tillmann V., Vahtra S., Heikkila M., Hirvasniemi M., Luopajarvi K., Johansson S., Kleemola P., Laukkanen E., Parkkola A., Pigg H. -M., Puttonen H., Renlund M., Salonen K., Suomalainen H., Tenkula T., Teramo K., Jarvenpaa A. -L., Hamalainen A. -M., Jussila R., Kiiveri S., Haavisto H., Holopainen S., Kupiainen H., Leeve T., Lumme K., Nironen T., Tenhola S., Tiilikainen T., Keinonen H., Lautala P., Salonen P., Vesanto M., Aspholm A. S., Asunta P., Ikavalko H., Jason E., Jaminki S., Kekki P., Koskinen M., Lehtimaki S., Lahde J., Makela M., Peltoniemi S., Poutiainen L., Ranta K., Salonsaari T., Sarviharju-Tujula S. -L., Selvenius J., Siljander H., Haanpaa P. -L., Holm C., Juutilainen A., Jarvelainen V., Kangaskolkka-Keskilohko A. -M., Laino E., Marjamaki L., Suominen E., Ylitalo S., Hokkanen M., Lounamaa R., Matikainen M., Nuuja A., Paalanen I., Puupponen A. R., Salo-Edwards H., Alanne S., Kultti T., Linjama H., Muhonen K., Vaaraniemi M., Talvitie T., Backman M., Hanhijarvi R., Koivula P., Lindstrom K., Martikainen A., Nurmi P., Bjork A., Huopio H., Komulainen J., Lehtomaki S., Muikku E., Pesola J., Sankilampi U., Arkkola T., Hekkala A., Jurvakainen S., Koivikko M. -L., Kahonen M., Leinonen E., Mykkanen T., Pohjola H., Riikonen K., Niittyvuopio A., Stenius A., Tapanainen P., Veijola R., Alar A., Jovio S., Korpela P., Makinen E., Hietanen L., Kivisto J., Kaar M. -L., Lehtimaki P., Mustila T., Popov E., Saatela S., Taittonen L., Ahtiainen K., Laaksonen N., Luoto M., Viitala J., Virransalo R., Nykanen P., Paajanen S., Parkkinen S., Pyrhonen H., Sarkka T., Aschemeier B., Bektas S., Biester T., Datz N., Deiss D., Fath M., Lupke K., Muller B., Nestoris C., Rothes S., Sadeghian E., Semler K., Arato A., Krikovszky D., Nobilis A., Szenasi J., Benevento D., Anguissola G. B., Biagioni M., Bizzarri C., Cherubini V., Ferrito L., Giordano C., Giorgetti C., Khazrai Y. M., Kyanvash S., Maddaloni E., Napoli A., Piergiovanni F., Pitocco D., Suraci T., Tabacco G., Valente L., Visalli N., Carboni M. B., Cavallo R., Cau V., Isola C., Ledda A., Loddo M., Mannu C., Pettinau M., Pisano S., Porceddu M., Putzu C., Rita A., Peters D., Schierloh U., Bisschoff M., Blonk L., Lappenschaar T., Manai B., Seesink M., Sperling-Conrad M., Verhagen M., Zoethout J. A., Basiak A., Chalas M., Chesiak M., Gramza A., Iwankiewicz J., Sieradzan E., Wikiera B., Ciechanowska M., Dziatkowiak H., Futona B., Gorska A., Glowacka-Wony M., Kaim I., Klich B., Starzyk J., Wolanin M., Tokarska L., Chucherco D., Deja G., Firek-Pedras M., Jarosz-Chobot P., Kalina M., Kutrowska-Adamusiak K., Minkina-Pedras M., Muchaka-Bianga M., Bodalski J., Mlynarski W., Szadkowska A., Cieslak A., Cypryk K., Dziatosz K., Jastzebowska J., Krysiak A., Szymanska U., Wilcznski J., Zawodniak-Szalapska M., Aguay A., Bilbao J. R., Chueca M., Cortazar A., Echarte G., Frutos T. G., Jimenez P., Martul P., Moreno A., Oyarzabal M., Rica I., Salgado Y., Martinez-Larrad M. T., Hawkins F. G., Hernandez R., Herranz L., Pallardo L. F., Deibarra L. S., Fernandez B. H., Luis J. L., Ortiz-Quintana L., Recarte P. P., Arnau D. R., Aronsson L., Boden S., Fredriksson J., Isacsson E., Johansson I., Karlsson E., Lock C., Sandstrom A. -M., Konefal M. S., Andreasson C., Dahlstrom U., Hanas R., Lundqvist K., Windell L., Jansson I., Karlsson A. -K., Lindbladh B., Odenman I., Pettersson C., Sundberg F., Sundqvist M., Aronsson S., Bellman I., Bengtsson A. -B., Lyden G. -B., Nilsson N. -O., Soderblom M., Unt C., Augustsson M., Bengtsson M., Fors H., Helmrich A., Johansson T. O., Andersson A. -C., Boiard-Stomlid A., Hellgren G., Kallsholm H., Lindqvist J., Nilsson M., Nordwall M., Stromstedt C., Ahsberg C., Lindh A., Lindhe C., Samuelsson C., Wiik A., Edenwall H., Ljumgcrantz M., Persson I. -B., Strigard E., Svensson B. -L., Aman J., Breivik G. -E., Detlofsson I. -L., Kroon M., Sarnblad S., Johansson C., Ilvered R., Lundberg A., Akesson K., Beccarelli A., Gadient M., Rappold-Amrein C., Schoenle E., Daftary A., Damagro-Elias M. E., Gilmour C., Klein M. B., Lain C., Salerno D., Smith M. E., Vats K., Pfaff D. J., Malone P., Mansfield P., Munns M., Nickel K., Pompilio K., Siemion W., Taculad R., Van Horn K., Zdanadewic M., Chambliss C., Jones J., Sadler M., Tanner-Blasiar M., Bell C., Camper N., Devaskar S., Devaskar U., Horowitz H., Rogers L., Shannahan R., Silk K., Bermudez Z., Colon R., Frazer T., Martinez-Nieves B., Torres J., Vega J., Chan M., Cook S., Goland R., Greenberg E., Jules N., Montes J., Nelson M., Parra-Valencia Z., Schachner H., Softness B., Kiviniemi M., Suomenin R., Alexander A., Hyrckowian E., Nichol L., Trucco M., Karjalainen E., Louhio T., Sarnesto A., Valtonen E., Davydova B., Helander S., Hamalainen J., Harkonen T., Joutsjoki L., Kararic M., Latva-Koivisto M., Lonn E., Nurmi T., Ollila I., Rinkinen J., Ronkainen M., Tukiainen H., Cederlof A., Kiikeri M., Tsupari S., Cheng R., Bryant K., Chan Y., Maezawa Y., Paltser G., Rasavi R., Tsui H., Winer S., Wu P., Yantha J., Pediatrics, Knip M., Akerblom H.K., Altaji E., Becker D., Bruining J., Castano L., Danne T., De Beaufort C., Dosch H.-M., Dupre J., Fraser W.D., Howard N., Ilonen J., Konrad D., Kordonouri O., Krischer J.P., Lawson M.L., Ludvigsson J., Madacsy L., Mahon J.L., Ormisson A., Palmer J.P., Pozzilli P., Savilahti E., Serrano-Rios M., Songini M., Taback S., Vaarala O., White N.H., Virtanen S.M., Wasikowa R., Mandrup-Poulsen T., Arjas E., Lernmark A., Laara E., Schmidt B., Hyytinen M., Koski K., Koski M., Merentie K., Pajakkala E., Reunanen A., Salonen M., Terhonen T., Virkkunen S., Cuthbertson D., Gainer B., Hadley D., Malloy J., Nallamshetty L., Shanker L., Bradley B., Lough G., Fraser W., Sermer M., Taback S.P., Franciscus M., Nucci A., Palmer J., Alahuhta K., Barlund S., Korhonen T., Kovanen L., Lehtonen E., Niinisto S., Pekkala M., Sorkio S., Toivanen L., Vahatalo L., Uusitalo U., Ohman T., Bongiorno R., Catteau J., Fraser G., Lloyd M., Crock P., Giles M., Siech K., See D.W., Brown C., Craig M., Johnston A., Bere L.J., Clarson C.L., Jenner M., McManus R., Renato N., Lovell M., Higo D., Kent N., Kwan J., Marshall C., Metzger D., Chanoine J.-P., Stewart L., Thompson D., Edwards A., Lange I., Mercer J., Pacaud D., Josephine H., Schwarz W., Stephure D.K., Boer J., Chatur T., Chick C., Couch B., Demianczuk N., Girgis R., Marks S., Ryan E., Thompson M., Dean H.J., Grant L., Hamelin K., LaForte J., Murphy L., Catte D., Schneider C., Sellers E.A.C., Woo V., Boland A., Clark H.D., Cooper T., Gruslin A., Karovitch A., Keely E., Malcolm J.C., Sauro V., Tawagi G.F., Andrighetti S., Arnold G., Barrett J., Blumer I., Daneman D., Donat D., Ehrlich R., Feig D., Gottesman I., Gysler M., Karkanis S., Kenshole A., Knight B., Lackie E., Lewis V., Martin M.J., Maxwell C., Oliver G., Panchum P., Shilletto N., Simone A., Skidmore M., Turrini T., Wong S., Allen C., Belanger L., Bouchard I., Ferland S., Frenette L., Garrido-Russo M., Leblanc M., Imbeault J., Morin V., Olivier G., Weisnagell J., Costain G., Dornan J., Heath K., MacSween M.-C., McGibbon A., Ramsay C., Sanderson F., Sanderson S., Benabdesselam L., Gonthier M., Huot C., Thibeault M., Laforte D., Legault L., Perron P., Armson A., Canning P., Cummings E.A., Ivanko V., McLeod L., Mokashi A., Scott K., Bridger T., Crane J., Crummell C., Curtis J.C., Dawson C., Joyce C., Newhook L.A., Newman S., Druken E., Begum-Hasan J., Breen A., Houlden R., Woods M., Carrson G., Kelly S., Martel M.J., Penner M., Sankaran K., Hardy-Brown K., King N., White R.A., Park M., Popkin J., Robson L., Coles K., Al Taji E., Cerna M., Cerny M., Francova H., Hainerova I., Kothankova H., Koukalova R., Krakorova V., Mendlova P., Sitova R., Stechova K., Vavrinec J., Vosahlo J., Zlatohlavkova B., Brazdova L., Faksova P., Gregorova D., Kantor L., Malkova K., Venhacova J., Venhacova P., Cipra A., Skvor J., Budejovice C., Tomsikova Z., Botkova-Krauseova H., Mockova A., Paterova P., Gogelova P., Kandrnalova J., Einberg U., Jakovlev U., Posiadlo S., Rannaste E., Raukas R., Riikjarv M.-A., Valla K., Astover V., Kirss A., Retpap J., Taht E., Tillmann V., Vahtra S., Heikkila M., Hirvasniemi M., Luopajarvi K., Johansson S., Kleemola P., Laukkanen E., Parkkola A., Pigg H.-M., Puttonen H., Renlund M., Salonen K., Suomalainen H., Tenkula T., Teramo K., Jarvenpaa A.-L., Hamalainen A.-M., Jussila R., Kiiveri S., Haavisto H., Holopainen S., Kupiainen H., Leeve T., Lumme K., Nironen T., Tenhola S., Tiilikainen T., Keinonen H., Lautala P., Salonen P., Vesanto M., Aspholm A.S., Asunta P., Ikavalko H., Jason E., Jaminki S., Kekki P., Koskinen M., Lehtimaki S., Lahde J., Makela M., Peltoniemi S., Poutiainen L., Ranta K., Salonsaari T., Sarviharju-Tujula S.-L., Selvenius J., Siljander H., Haanpaa P.-L., Holm C., Juutilainen A., Jarvelainen V., Kangaskolkka-Keskilohko A.-M., Laino E., Marjamaki L., Suominen E., Ylitalo S., Hokkanen M., Lounamaa R., Matikainen M., Nuuja A., Paalanen I., Puupponen A.R., Salo-Edwards H., Alanne S., Kultti T., Linjama H., Muhonen K., Vaaraniemi M., Talvitie T., Backman M., Hanhijarvi R., Koivula P., Lindstrom K., Martikainen A., Nurmi P., Bjork A., Huopio H., Komulainen J., Lehtomaki S., Muikku E., Pesola J., Sankilampi U., Arkkola T., Hekkala A., Jurvakainen S., Koivikko M.-L., Kahonen M., Leinonen E., Mykkanen T., Pohjola H., Riikonen K., Niittyvuopio A., Stenius A., Tapanainen P., Veijola R., Alar A., Jovio S., Korpela P., Makinen E., Hietanen L., Kivisto J., Kaar M.-L., Lehtimaki P., Mustila T., Popov E., Saatela S., Taittonen L., Ahtiainen K., Laaksonen N., Luoto M., Viitala J., Virransalo R., Nykanen P., Paajanen S., Parkkinen S., Pyrhonen H., Sarkka T., Aschemeier B., Bektas S., Biester T., Datz N., Deiss D., Fath M., Lupke K., Muller B., Nestoris C., Rothes S., Sadeghian E., Semler K., Arato A., Krikovszky D., Nobilis A., Szenasi J., Benevento D., Anguissola G.B., Biagioni M., Bizzarri C., Cherubini V., Ferrito L., Giordano C., Giorgetti C., Khazrai Y.M., Kyanvash S., Maddaloni E., Napoli A., Piergiovanni F., Pitocco D., Suraci T., Tabacco G., Valente L., Visalli N., Carboni M.B., Cavallo R., Cau V., Isola C., Ledda A., Loddo M., Mannu C., Pettinau M., Pisano S., Porceddu M., Putzu C., Rita A., Peters D., Schierloh U., Bisschoff M., Blonk L., Lappenschaar T., Manai B., Seesink M., Sperling-Conrad M., Verhagen M., Zoethout J.A., Basiak A., Chalas M., Chesiak M., Gramza A., Iwankiewicz J., Sieradzan E., Wikiera B., Ciechanowska M., Dziatkowiak H., Futona B., Gorska A., Glowacka-Wony M., Kaim I., Klich B., Starzyk J., Wolanin M., Tokarska L., Chucherco D., Deja G., Firek-Pedras M., Jarosz-Chobot P., Kalina M., Kutrowska-Adamusiak K., Minkina-Pedras M., Muchaka-Bianga M., Bodalski J., Mlynarski W., Szadkowska A., Cieslak A., Cypryk K., Dziatosz K., Jastzebowska J., Krysiak A., Szymanska U., Wilcznski J., Zawodniak-Szalapska M., Aguay A., Bilbao J.R., Chueca M., Cortazar A., Echarte G., Frutos T.G., Jimenez P., Martul P., Moreno A., Oyarzabal M., Rica I., Salgado Y., Martinez-Larrad M.T., Hawkins F.G., Hernandez R., Herranz L., Pallardo L.F., Deibarra L.S., Fernandez B.H., Luis J.L., Ortiz-Quintana L., Recarte P.P., Arnau D.R., Aronsson L., Boden S., Fredriksson J., Isacsson E., Johansson I., Karlsson E., Lock C., Sandstrom A.-M., Konefal M.S., Andreasson C., Dahlstrom U., Hanas R., Lundqvist K., Windell L., Jansson I., Karlsson A.-K., Lindbladh B., Odenman I., Pettersson C., Sundberg F., Sundqvist M., Aronsson S., Bellman I., Bengtsson A.-B., Lyden G.-B., Nilsson N.-O., Soderblom M., Unt C., Augustsson M., Bengtsson M., Fors H., Helmrich A., Johansson T.O., Andersson A.-C., Boiard-Stomlid A., Hellgren G., Kallsholm H., Lindqvist J., Nilsson M., Nordwall M., Stromstedt C., Ahsberg C., Lindh A., Lindhe C., Samuelsson C., Wiik A., Edenwall H., Ljumgcrantz M., Persson I.-B., Strigard E., Svensson B.-L., Aman J., Breivik G.-E., Detlofsson I.-L., Kroon M., Sarnblad S., Johansson C., Ilvered R., Lundberg A., Akesson K., Beccarelli A., Gadient M., Rappold-Amrein C., Schoenle E., Daftary A., Damagro-Elias M.E., Gilmour C., Klein M.B., Lain C., Salerno D., Smith M.E., Vats K., Pfaff D.J., Malone P., Mansfield P., Munns M., Nickel K., Pompilio K., Siemion W., Taculad R., Van Horn K., Zdanadewic M., Chambliss C., Jones J., Sadler M., Tanner-Blasiar M., Bell C., Camper N., Devaskar S., Devaskar U., Horowitz H., Rogers L., Shannahan R., Silk K., Bermudez Z., Colon R., Frazer T., Martinez-Nieves B., Torres J., Vega J., Chan M., Cook S., Goland R., Greenberg E., Jules N., Montes J., Nelson M., Parra-Valencia Z., Schachner H., Softness B., Kiviniemi M., Suomenin R., Alexander A., Hyrckowian E., Nichol L., Trucco M., Karjalainen E., Louhio T., Sarnesto A., Valtonen E., Davydova B., Helander S., Hamalainen J., Harkonen T., Joutsjoki L., Kararic M., Latva-Koivisto M., Lonn E., Nurmi T., Ollila I., Rinkinen J., Ronkainen M., Tukiainen H., Cederlof A., Kiikeri M., Tsupari S., Cheng R., Bryant K., Chan Y., Maezawa Y., Paltser G., Rasavi R., Tsui H., Winer S., Wu P., Yantha J., University of Zurich, and Knip, Mikael

Subjects
Male, Risk, medicine.medical_specialty, Casein, Breastfeeding, 030209 endocrinology & metabolism, 610 Medicine & health, 2700 General Medicine, Endocrinology and Diabetes, Disease-Free Survival, law.invention, Follow-Up Studie, Nutrition Policy, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, Double-Blind Method, SDG 3 - Good Health and Well-being, law, Internal medicine, Diabetes mellitus, medicine, Humans, Cumulative incidence, 030212 general & internal medicine, Child, Infant Nutritional Physiological Phenomena, Original Investigation, 2. Zero hunger, Type 1 diabetes, business.industry, Hazard ratio, Absolute risk reduction, Infant, Newborn, Caseins, General Medicine, ta3121, medicine.disease, Infant Formula, 3. Good health, Diabetes Mellitus, Type 1, Infant formula, 10036 Medical Clinic, Endokrinologi och diabetes, Female, business, Human, Follow-Up Studies
Abstract

IMPORTANCE Early exposure to complex dietary proteins may increase the risk of type 1 diabetes in children with genetic disease susceptibility. There are no intact proteins in extensively hydrolyzed formulas. OBJECTIVE To test the hypothesis that weaning to an extensively hydrolyzed formula decreases the cumulative incidence of type 1 diabetes in young children. DESIGN, SETTING, AND PARTICIPANTS An international double-blind randomized clinical trial of 2159 infants with human leukocyte antigen-conferred disease susceptibility and a first-degree relative with type 1 diabetes recruited from May 2002 to January 2007 in 78 study centers in 15 countries; 1081 were randomized to be weaned to the extensively hydrolyzed casein formula and 1078 to a conventional formula. The follow-up of the participants ended on February 28, 2017. INTERVENTIONS The participants received either a casein hydrolysate or a conventional adapted cows milk formula supplemented with 20% of the casein hydrolysate. The minimum duration of study formula exposure was 60 days by 6 to 8 months of age. MAIN OUTCOMES AND MEASURES Primary outcome was type 1 diabetes diagnosed according to World Health Organization criteria. Secondary outcomes included age at diabetes diagnosis and safety (adverse events). RESULTS Among 2159 newborn infants (1021 female [47.3%]) who were randomized, 1744 (80.8%) completed the trial. The participants were observed for a median of 11.5 years (quartile [Q] 1-Q3, 10.2-12.8). The absolute risk of type 1 diabetes was 8.4% among those randomized to the casein hydrolysate (n = 91) vs 7.6% among those randomized to the conventional formula (n = 82) (difference, 0.8%[95% CI, -1.6% to 3.2%]). The hazard ratio for type 1 diabetes adjusted for human leukocyte antigen risk group, duration of breastfeeding, duration of study formula consumption, sex, and region while treating study center as a random effect was 1.1 (95% CI, 0.8 to 1.5; P = .46). The median age at diagnosis of type 1 diabetes was similar in the 2 groups (6.0 years [Q1-Q3, 3.1-8.9] vs 5.8 years [Q1-Q3, 2.6-9.1]; difference, 0.2 years [95% CI, -0.9 to 1.2]). Upper respiratory infections were the most common adverse event reported (frequency, 0.48 events/year in the hydrolysate group and 0.50 events/year in the control group). CONCLUSIONS AND RELEVANCE Among infants at risk for type 1 diabetes, weaning to a hydrolyzed formula compared with a conventional formula did not reduce the cumulative incidence of type 1 diabetes after median follow-up for 11.5 years. These findings do not support a need to revise the dietary recommendations for infants at risk for type 1 diabetes. Funding Agencies|Eunice Kennedy Shriver National Institute of Child Health and Development (NICHD); National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health [HD040364, HD042444, HD051997]; Canadian Institutes of Health Research; Commission of the European Communities [QLK1-2002-00372]; European Foundation for the Study of Diabates/JDRF/Novo Nordisk; Academy of Finland (Centre of Excellence in Molecular Systems Immunology and Physiology Research) [250114]; Dutch Diabetes Research Foundation; Finnish Diabetes Research Foundation; JDRF

Published
2018

170. Length of synostosis and segmented intracranial volume correlate with age in patients with non-syndromic sagittal synostosis

Author

Arja Heliövaara, Mika P. Koivikko, Junnu Leikola, Virve Koljonen, Pia Vuola, Plastiikkakirurgian yksikkö, Clinicum, University of Helsinki, HUS Musculoskeletal and Plastic Surgery, Department of Diagnostics and Therapeutics, and HUS Medical Imaging Center

Subjects
Male, medicine.medical_specialty, INFANTS, 3124 Neurology and psychiatry, Craniosynostosis, Craniosynostoses, Synostosis length, SUTURE, 03 medical and health sciences, Imaging, Three-Dimensional, 0302 clinical medicine, Intracranial volume, Cranial vault, Humans, Medicine, Retrospective Studies, business.industry, Age Factors, Infant, Newborn, Scaphocephaly, 3112 Neurosciences, Infant, Cranial Sutures, General Medicine, Cone-Beam Computed Tomography, Plastic Surgery Procedures, Synostosis, 3126 Surgery, anesthesiology, intensive care, radiology, medicine.disease, Sagittal suture, medicine.anatomical_structure, Sagittal synostosis, Child, Preschool, 030220 oncology & carcinogenesis, Pediatrics, Perinatology and Child Health, Female, Neurology (clinical), Neurosurgery, business, Nuclear medicine, 030217 neurology & neurosurgery
Abstract

The aim of this study is to compare the length of synostosis and segmented intracranial volume (SIV) with age in children with non-syndromic sagittal synostosis. Thirty-three consecutive patients (22 boys) who had been operated by cranial vault remodeling because of sagittal synostosis were compared retrospectively from 3D-CT imaging data sets obtained from volumetric CT. The mean age of the patients at preoperative CT imaging was 0.49 (range 0.13-1.3) years and at 1-year postoperative imaging 1.8 (range 1.3-3) years. The mean interval between preoperative CT imaging and surgery was 0.25 (range 0-0.8) years. Pearson's correlation and Student's t test were used in the statistical analyses. Length of sagittal synostosis correlated positively with age at preoperative CT (r = 0.688, p

Published
2017
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171. Defensive role of macroalgal phlorotannins: benefits and trade-offs under natural herbivory

Author

Riitta Koivikko, Veijo Jormalainen, and Fiia Haavisto

Subjects
0106 biological sciences, Herbivore, Ecology, 010604 marine biology & hydrobiology, Trade offs, Fucus vesiculosus, Aquatic Science, Biology, Trade-off, biology.organism_classification, 010603 evolutionary biology, 01 natural sciences, Natural (archaeology), Idotea balthica, ta1181, Ecology, Evolution, Behavior and Systematics
Published
2017
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172. Drives and objects - notes on the change of drive theory

Author

Tiina Koivikko

Subjects
Cognitive science, Unconscious mind, Metaphor, media_common.quotation_subject, 05 social sciences, 050108 psychoanalysis, Psychiatry and Mental health, Clinical Psychology, Work (electrical), 050903 gender studies, Object relations theory, 0501 psychology and cognitive sciences, Sociology, 0509 other social sciences, Social psychology, media_common
Abstract

Freud’s drive theory has been questioned since the 1940s when Fairbairn created a metaphor of the mind that is not based on the tripartite model and drive theory. His work inspired others to elabor...

Published
2017
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174. Potential of heart fatty-acid binding protein, neurofilament light, interleukin-10 and S100 calcium-binding protein B in the acute diagnostics and severity assessment of traumatic brain injury.

Author

Koivikko, Pia, Posti, Jussi P., Mohammadian, Mehrbod, Lagerstedt, Linnea, Azurmendi, Leire, Hossain, Iftakher, Katila, Ari J., Menon, David, Newcombe, Virginia F. J., Hutchinson, Peter John, Maanpää, Henna-Riikka, Tallus, Jussi, Zetterberg, Henrik, Blennow, Kaj, Tenovuo, Olli, Sanchez, Jean-Charles, and Takala, Riikka S. K.

Abstract

Background: There is substantial interest in blood biomarkers as fast and objective diagnostic tools for traumatic brain injury (TBI) in the acute setting.Methods: Adult patients (≥18) with TBI of any severity and indications for CT scanning and orthopaedic injury controls were prospectively recruited during 2011-2013 at Turku University Hospital, Finland. The severity of TBI was classified with GCS: GCS 13-15 was classified as mild (mTBI); GCS 9-12 as moderate (moTBI) and GCS 3-8 as severe (sTBI). Serum samples were collected within 24 hours of admission and biomarker levels analysed with high-performance kits. The ability of biomarkers to distinguish between severity of TBI and CT-positive and CT-negative patients was assessed.Results: Among 189 patients recruited, neurofilament light (NF-L) was obtained from 175 patients with TBI and 40 controls. S100 calcium-binding protein B (S100B), heart fatty-acid binding protein (H-FABP) and interleukin-10 (IL-10) were analysed for 184 patients with TBI and 39 controls. There were statistically significant differences between levels of all biomarkers between the severity classes, but none of the biomarkers distinguished patients with moTBI from patients with sTBI. Patients with mTBI discharged from the ED had lower levels of IL-10 (0.26, IQR=0.21, 0.39 pg/mL), H-FABP (4.15, IQR=2.72, 5.83 ng/mL) and NF-L (8.6, IQR=6.35, 15.98 pg/mL) compared with those admitted to the neurosurgical ward, IL-10 (0.55, IQR=0.31, 1.42 pg/mL), H-FABP (6.022, IQR=4.19, 20.72 ng/mL) and NF-L (13.95, IQR=8.33, 19.93 pg/mL). We observed higher levels of H-FABP and NF-L in older patients with mTBI. None of the biomarkers or their combinations was able to distinguish CT-positive (n=36) or CT-negative (n=58) patients with mTBI from controls.Conclusions: S100B, H-FABP, NF-L and IL-10 levels in patients with mTBI were significantly lower than in patients with moTBI and sTBI but alone or in combination, were unable to distinguish patients with mTBI from orthopaedic controls. This suggests these biomarkers cannot be used alone to diagnose mTBI in trauma patients in the acute setting. [ABSTRACT FROM AUTHOR]

Published
2022
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175. Tactile Electronic Skin Based on Conductive Fabric for Robotic Hand Applications

Author

Veikko Sariola, Anastasia Koivikko, and Ahmed Elsayes

Subjects
Rapid prototyping, Materials science, business.industry, Capacitive sensing, Electronic skin, Linearity, Wearable computer, 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, Artificial skin, 0104 chemical sciences, Optoelectronics, 0210 nano-technology, business, Electrical conductor, Tactile sensor
Abstract

Tactile electronic skin (e-skin) has multitude of potential applications, such as a prosthetic artificial skin, wearable sensors and health monitoring. However, current fabrication methods tend to involve complex processing or materials that are not widely available. In this paper, we show that high quality capacitive tactile sensors for an e-skin can be fabricated by sandwiching a microstructured dielectric elastomer layer between two conductive fabric electrodes. The fabric can be easily cut to quickly prototype different sensor configuration and can be bent into three dimensional shapes. The fabricated sensors display excellent linearity and very little long-term drift. We demonstrate the integration of these sensors in an anthropomorphic robotic hand, which is entirely fabricated using rapid prototyping techniques.

Published
2019
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176. Interlaboratory Proficiency Test 13/2018 - Leaching behavior test for solid waste material: One stage batch leaching test

Author

Koivikko, Riitta, Leivuori, Mirja, Kaasalainen, Marika, Tervonen, Keijo, Lanteri, Sari, and Ilmakunnas, Markku

Subjects
jäte, pätevyys, liukoisuus, pätevyyskoe, laboratoriot
Abstract

Proftest SYKE carried out the proficiency test in cooperation with KVVY Tutkimus Oy for the laboratories conducting leaching tests for solid waste material in November-December 2018. The results of the one stage batch leaching test (EN 12457-2) for foundry sand samples were compared and evaluated. The tested measurands were metals (As, Ba, Cd, Cr, Cu, Hg, Mo, Ni, Pb, Sb, Se, V, Zn), Cl-, SO4 2-, F-, DOC, pH, and conductivity. In total, 10 participants joined in the proficiency test. In this PT for all the evaluated measurands the median of the results reported by the participants was used as the assigned value. The measurands Ba, conductivity, DOC, Ni, pH, SO4, and Zn were evaluated with z scores and of those results 92 % were satisfactory, when deviation of 0.3 pH units and 20–30 % for other measurands was accepted from the assigned value. Further, measurands As, Cr, Cu, and V were evaluated with En scores and 76 % of the results were satisfactory. Warm thanks to all participants in this proficiency test!

Published
2019

177. Interlaboratory Proficiency Test 01/2019 - Swimming pool water analysis

Author

Leivuori, Mirja, Tyrväinen, Sami, Sarkkinen, Mika, Koivikko, Riitta, Tervonen, Keijo, Lanteri, Sari, Väisänen, Ritva, and Ilmakunnas, Markku

Subjects
uimavesi, pätevyys, vesianalyysi, pätevyyskoe, laboratoriot
Abstract

Proftest SYKE carried out the proficiency test for the determination of chlorine, KMnO4, NO3, pH, turbidity, and urea in swimming pool waters in January-February 2019. In total, 22 participants joined in the proficiency test. In this proficiency test 93 % of the results evaluated with z score were satisfactory when deviation of 0.2 pH units for pH determination and 10–25 % for the other determinations was accepted from the assigned value. Of the results evaluated with En scores, 71 % were satisfactory. The calculated value, the robust mean or the median of the results reported by the participants was chosen as the assigned value for the concentration of measurands. Warm thanks to all participants in this proficiency test!

Published
2019

178. Tuning the stability of alkoxyisopropyl protection groups

Author

Mikko Oivanen, Henna Koivikko, Petri Heinonen, Zehong Liang, and Department of Chemistry

Subjects
Silylation, acetal, 116 Chemical sciences, 010402 general chemistry, 01 natural sciences, Medicinal chemistry, Full Research Paper, lcsh:QD241-441, Hydrolysis, chemistry.chemical_compound, Column chromatography, lcsh:Organic chemistry, DETRITYLATION, lcsh:Science, chemistry.chemical_classification, 010405 organic chemistry, Silica gel, Acetal, Organic Chemistry, 0104 chemical sciences, Chemistry, chemistry, hydrolysis, Reagent, Alkoxy group, Enol ether, lcsh:Q, protecting groups
Abstract

Five different 2-alkoxypropan-2-yl groups are introduced as acid-labile protecting groups for the 5’- and 3’-hydroxy groups of a 2’-deoxynucleoside. All studied protecting groups were readily introduced with good to excellent yields using the appropriate enol ether as a reagent and 0.5 to 1 mol % p-toluenesulfonic acid as a catalyst. The protected compounds could be purified by silica gel column chromatography without degradation. The compatibility of these protecting groups in parallel use with benzoyl and silyl groups was verified. The stabilities of the different alkoxy acetal protecting groups were compared by following the kinetics of their hydrolysis at 25.0 °C in buffered solutions through an HPLC method. In the pH range 4.94 to 6.82 the hydrolysis reactions are of first order in the hydronium ion. The rate of hydrolysis correlates with the electron-donating or electron-withdrawing ability of the corresponding alkoxy group. The studied 2-alkoxypropan-2-yl groups and the relative rate constants for their cleavage from the 5’-hydroxy group of 2’-deoxythymidine were: cyclohexyloxy (krel = 7.7), isopropoxy (7.4), methoxy (1), benzyloxy (0.6) and 2,2,2-trifluoroethyloxy (0.04). The attachment of the same groups to the 3’-hydroxy group are from 1.3 to 1.9-fold more stable. The most reactive of these acetone-based acetal groups are faster removed than a dimethoxytrityl group, and they are easier to cleave completely in solution. The structural variation allows steering of the stability and lipophilicity of the compounds in some range.

Published
2019

179. Laboratorioiden välinen pätevyyskoe 14/2018 - Alkaliniteetti, ravinteet, pH, sähkönjohtavuus ja väri jätevesistä

Author

Koivikko, Riitta, Leivuori, Mirja, Sarkkinen, Mika, Tervonen, Keijo, Lanteri, Sari, Väisänen, Ritva, and Ilmakunnas, Markku

Subjects
pätevyys, vesianalyysi, pätevyyskoe, jätevesi, laboratoriot
Abstract

Proftest SYKE järjesti marras-joulukuussa 2018 pätevyyskokeen jätevesiä analysoiville laboratorioille. Pätevyyskokeessa määritettiin alkaliniteetti, ravinteet (NNH4, NNO2+NO3, Ntot, PPO4, Ptot), pH, sähkönjohtavuus ja väri synteettisestä näytteestä, viemärilaitoksen sekä massa- ja paperiteollisuuden jätevedestä. Pätevyyskokeeseen osallistui yhteensä 55 laboratoriota. Testisuureen vertailuarvona käytettiin laskennallista pitoisuutta, osallistujien tulosten robustia keskiarvoa, keskiarvoa tai mediaania. Osallistujien pätevyyden arviointi tehtiin z- ja En-arvojen avulla. Koko tulosaineistossa oli z-arvoilla arvioituna 89 % hyväksyttäviä tuloksia, kun vertailuarvosta sallittiin pH-määrityksissä 0,2 pH-yksikön ja muissa määrityksissä 5–20 %:n poikkeama. Näytteen P2V värimääritystulokset arvioitiin käyttäen En-arvoja ja näistä 80 % oli hyväksyttäviä. Kiitos pätevyyskokeen osallistujille!

Published
2019

180. Laboratorioiden välinen pätevyyskoe 12/2018 - PAH- ja PCB-yhdisteet sekä öljyhiilivedyt maasta

Author

Koivikko, Riitta, Nuutinen, Jari, and Ilmakunnas, Markku

Subjects
pätevyys, pätevyyskoe, laboratoriot, maa-analyysi
Abstract

Proftest SYKE järjesti marraskuussa 2018 pätevyyskokeen laboratorioille, jotka määrittävät PAH- ja PCB-yhdisteitä sekä öljyhiilivetyjä maasta (ORG 12/2018). Osallistujille toimitettiin synteettiset näytteet jokaisesta yhdisteryhmästä sekä yksi saastunut maanäyte. Pätevyyskokeeseen osallistui yhteensä 9 laboratoriota. Testisuureen vertailuarvona käytettiin laskennallista pitoisuutta, osallistujien tulosten mediaania tai keskiarvoa. Osallistujien pätevyyden arviointi tehtiin z- ja En-arvojen avulla. Koko tulosaineistosta hyväksyttäviä tuloksia oli z-arvojen perusteella 69 %, kun vertailuarvosta sallittiin 15–30 %:n poikkeama. Tuloksista, jotka arvioitiin En-arvoilla, oli hyväksyttäviä 66 %. Kiitos pätevyyskokeen osallistujille!

Published
2019

181. Additional squamosal suture synostosis and segmented intracranial volume in patients with non-syndromic sagittal synostosis

Author

Arja Heliövaara, Virve Koljonen, Junnu Leikola, Mika P. Koivikko, Plastiikkakirurgian yksikkö, Clinicum, HUS Musculoskeletal and Plastic Surgery, Department of Diagnostics and Therapeutics, and HUS Medical Imaging Center

Subjects
Male, Squamosal suture, 030230 surgery, Brief Communication, 3124 Neurology and psychiatry, Craniosynostosis, 03 medical and health sciences, Craniosynostoses, 0302 clinical medicine, 3123 Gynaecology and paediatrics, Intracranial volume, Cranial vault, medicine, Humans, Retrospective Studies, business.industry, Scaphocephaly, 3112 Neurosciences, Infant, General Medicine, Synostosis, medicine.disease, 3126 Surgery, anesthesiology, intensive care, radiology, Sagittal suture, medicine.anatomical_structure, Sagittal synostosis, 030220 oncology & carcinogenesis, Child, Preschool, Pediatrics, Perinatology and Child Health, Female, Neurology (clinical), Nuclear medicine, business
Abstract

PurposeTo evaluate the incidence of squamosal suture synostosis (SQS) in children with non-syndromic sagittal synostosis and to evaluate whether the additional SQS affects the intracranial volume (ICV).MethodsThirty-four consecutive patients (23 boys) who had been operated by cranial vault remodelling because of sagittal synostosis were compared retrospectively from 3D-CT imaging data sets obtained from volumetric CT. The mean age of the patients at preoperative CT imaging was 0.48 (range 0.13-1.3) years. Mann-Whitney U test was used in the statistical analyses.ResultsSagittal synostosis was combined with SQS in four children (11.7%) but the additional SQS did not affect the ICV. SQS was unilateral in all children, two were located on the right and two on the left side. The length of the SQS varied between 4 and 27mm. The children with SQS had a shorter sagittal suture synostosis length ratio (length of synostosis/total sagittal suture lengthx100) than those without SQS.ConclusionsThe incidence of SQS in non-syndromic sagittal synostosis was 11.7% but SQS did not affect the ICV.

Published
2019

182. Laboratorioiden välinen vertailumittaus 16/2018 - Materiaalinäytteiden asbestimääritykset

Author

Koivikko, Riitta, Leivuori, Mirja, Lallukka, Heli, Lindström, Annika, Tervonen, Keijo, Lanteri, Sari, and Ilmakunnas, Markku

Subjects
pätevyys, pätevyyskoe, asbesti, laboratoriot
Abstract

Proftest SYKE järjesti yhteistyössä Työterveyslaitoksen (TTL) kanssa syksyllä 2018 ensimmäisen kansallisen vertailumittauksen toimijoille, jotka tekevät materiaalinäytteiden asbestimäärityksiä (ABS 16/2018). Vertailumittauksen osallistujille toimitettiin neljä rakennusmateriaalinäytettä, joista analysoitiin asbestin läsnäolo tai puuttuminen sekä tunnistetut asbestisilikaattimineraalit. Vertailumittaukseen osallistui yhteensä 19 toimijaa. Osallistujatulosten arviointi perustui testinäytteiden raportoituihin tuloksiin ja osallistujatuloksia verrattiin asiantuntijalaboratoriossa tehtyihin asbestianalyyseihin. Sekä hyväksyttäviä asbestimääritystuloksia että hyväksyttäviä asbestitunnistustuloksia oli tulosaineistossa 99 %. Kiitos vertailumittauksen osallistujille!

Published
2019

183. Interlaboratory comparison 09/2018 - VOC measurement from indoor air samples

Author

Leivuori, Mirja, Hovi, Hanna, Koivikko, Riitta, Tervonen, Keijo, Lanteri, Sari, and Ilmakunnas, Markku

Subjects
pätevyys, sisäilma, pätevyyskoe, laboratoriot
Abstract

Proftest SYKE carried out the interlaboratory comparison in cooperation with Finnish Institute of Occupational Health (FIOH) for VOC thermodesorption measurements (ISO 16000-6) from native indoor air samples in Tenax TA thermodesorption tubes (IDA 09/2018) in October 2018. Further, the measurements of alpha-pinene, 1-butanol, 2-butoxyethanol, 2EH (2-ethyl-1-hexanol), naphthalene, styrene, tetrachloroethylene, toluene, and TXIB (2,2,4-trimethyl-1,3-pentanediol diisobutyrate) were tested from the synthetic sample. In total eight participants took part in the comparison. In total 70 % of the results reported by the participants were satisfactory when deviation of 20–30 % from the assigned value was accepted. The calculated values were used as the assigned values for the results of the synthetic sample reported as compound specific responses. For the other measurands and samples the mean of the results of the homogeneity measurements of the expert laboratory were used as the assigned value. The performance evaluation was based on the z scores. Warm thanks to all the participants of this interlaboratory comparison!

Published
2019

184. Luukasvainpotilaan diagnostinen polku ja hyvänlaatuiset luukasvaimet

Author

Koivikko, Mika, Haapamäki, Ville, Diagnostis-terapeuttinen osasto, and HUS Kuvantaminen

Subjects
+diagnostic imaging, +diagnosis, 3126 Kirurgia, anestesiologia, tehohoito, radiologia, Bone Neoplasms, +classification
Abstract

Teema : luukasvaimet. English summary

Published
2019

185. Laboratorioiden välinen pätevyyskoe 03/2019 - BOD7, CODCr, CODMn, kiintoaine, Na ja TOC jätevesistä

Author

Koivikko, Riitta, Leivuori, Mirja, Näykki, Teemu, Sarkkinen, Mika, Sara-Aho, Timo, Tervonen, Keijo, Lanteri, Sari, Väisänen, Ritva, and Ilmakunnas, Markku

Subjects
pätevyys, vesianalyysi, pätevyyskoe, jätevesi, laboratoriot
Abstract

Proftest SYKE järjesti maaliskuussa 2019 pätevyyskokeen jätevesiä analysoiville laboratorioille. Pätevyyskokeessa määritettiin BOD7, CODCr, CODMn, kiintoaine, Na ja TOC synteettisestä näytteestä, viemärilaitoksen sekä massa- ja paperiteollisuuden jätevesistä. BOD7 ja CODMn määritettiin myös luonnonvedestä. Pätevyyskokeeseen osallistui yhteensä 61 laboratoriota. Testisuureen vertailuarvona käytettiin teoreettista (laskennallista) pitoisuutta tai osallistujien tulosten robustia keskiarvoa. Osallistujien pätevyyden arviointi tehtiin z-arvojen avulla. Koko tulosaineistossa oli 91 % hyväksyttäviä tuloksia, kun vertailuarvosta sallittiin 10–30 %:n poikkeama. Kiitos pätevyyskokeen osallistujille!

Published
2019

186. Laboratorioiden välinen pätevyyskoe 09/2019 - Talousvesimääritykset

Author

Björklöf, Katarina, Koivikko, Riitta, Sara-Aho, Timo, Sarkkinen, Mika, Tervonen, Keijo, Lanteri, Sari, Väisänen, Ritva, and Ilmakunnas, Markku

Subjects
pätevyys, vesianalyysi, pätevyyskoe, talousvesi, laboratoriot
Abstract

Proftest SYKEn järjestämään pätevyyskokeeseen talous- ja kaivovesimääritysten testisuureille osallistui 40 osallistujaa. Tuloksia arvioitiin z-arvon avulla käyttäen tavoitehajontana pH-määrityksissä 0,2 pH-yksikköä ja muissa määrityksissä 5-40 % 95 %:n luottamusvälillä. Koko tulosaineistossa oli hyväksyttäviä tuloksia 91 %. Hyväksyttävien tulosten määrä oli hieman korkeampi kuin edellisessä talousvesivertailussa. Näytteiden homogeenisuus ja säilyvyys täyttivät laatukriteerit testattujen testisuureiden osalta (pH, NH4 ja alkaliniteetti). Menetelmävertailuissa todettiin talousvesinäytteen nitriittituloksissa tilastollisesti merkitsevä ero manuaalisen ja automaattisen sulfaniiliamidimenetelmän ja muiden menetelmien välillä. Kiitos pätevyyskokeen osallistujille!

Published
2019

187. Interlaboratory Proficiency Test 04/2019 - Metals in natural water and sediment

Author

Leivuori, Mirja, Koivikko, Riitta, Sara-Aho, Timo, Näykki, Teemu, Tervonen, Keijo, Lanteri, Sari, Väisänen, Ritva, and Ilmakunnas, Markku

Subjects
vesianalyysi, sedimentti, pätevyyskoe, laboratoriot
Abstract

Proftest SYKE carried out the proficiency test (PT) for analysis of elements in ground and domestic waters as well as in sediment in April 2019. The measurands for the synthetic sample and domestic and ground water samples were: Al, As, Cd, Co, Cr, Cu, Fe, Hg, Mn, Ni, Pb, Se, Ti, U, V, and Zn. In addition to the aforementioned, also measurands Ntot, Ptot, Stot, TC, and dry weight (Drw) were analysed from the sediment sample. In total 20 participants joined in the PT. In this proficiency test 91 % of the results valuated based on z score were satisfactory when deviation of 10–25 % from the assigned value was accepted. From the results evaluated with En scores, 90 % were satisfactory. Basically, either the metrologically traceable concentration, the calculated concentration, the robust mean or the median of the results reported by the participants was used as the assigned value for the measurands. Warm thanks to all the participants of this proficiency test!

Published
2019

188. Interlaboratory Proficiency Test 02/2019 - Chlorophyll a, colour, conductivity, nutrients, pH and turbidity in natural waters

Author

Koivikko, Riitta, Leivuori, Mirja, Sarkkinen, Mika, Tervonen, Keijo, Lanteri, Sari, Väisänen, Ritva, and Ilmakunnas, Markku

Subjects
pätevyys, vesianalyysi, pätevyyskoe, laboratoriot
Abstract

Proftest SYKE carried out the proficiency test for the determination of chlorophyll a, colour, conductivity, nutrients, pH, and turbidity in natural waters in February 2019. In total, there were 34 participants in the proficiency test. Either the calculated concentration, the robust mean or the median of the results reported by the participants was used as the assigned value for the measurands. The overall performance of the participants was evaluated by using z scores. In this proficiency test 85 % of the results were satisfactory when total deviation of 0.2 pH units for pH values and 5–35 % for the other measurands was accepted from the assigned value. Warm thanks to all participants in this proficiency test!

Published
2019

189. Interlaboratory Proficiency Test 07/2019 - Gross and net calorific values in fuels

Author

Leivuori, Mirja, Hatanpää, Eliisa, Koivikko, Riitta, Tervonen, Keijo, Lanteri, Sari, and Ilmakunnas, Markku

Subjects
pätevyys, polttoaineet, technology, industry, and agriculture, pätevyyskoe, laboratoriot, complex mixtures
Abstract

Proftest SYKE arranged the proficiency test (PT) for the measurements of the gross and net calorific value, the content of ash, carbon, nitrogen, hydrogen, moisture, sulphur, and volatile matter in peat, wood pellet (not sulphur) and coal samples in August-September 2019. In total, there were 34 participants in the PT. The participants could also estimate the emission factor for the peat and coal samples. The robust mean or the median of the results reported by the participants was used as the assigned value for measurements. The performance evaluation was based on the z scores. In total, 90 % of the reported results were satisfactory, when the deviation of 1–30 % from the assigned value was accepted. For the gross calorific value measurements 93 % of the peat sample results, 76 % of the wood pellet sample results, and 86 % of the coal sample results were satisfactory. For the net calorific value measurements 82 % of the peat sample results, 88 % of the wood pellet results, and 93 % of the coal sample results were satisfactory. The performance evaluation was not done for the measurements of Mad in all samples, Nd in the wood pellet sample, and emission factor in peat and coal sample. Warm thanks to all the participants in this proficiency test!

Published
2019

190. Early probiotic supplementation and the risk of celiac disease in children at genetic risk

Author

Uusitalo, U. (Ulla), Aronsson, C. A. (Carin Andren), Liu, X. (Xiang), Kurppa, K. (Kalle), Yang, J. (Jimin), Liu, E. (Edwin), Skidmore, J. (Jennifer), Winkler, C. (Christiane), Rewers, M. J. (Marian J.), Hagopian, W. A. (William A.), She, J.-X. (Jin-Xiong), Toppari, J. (Jorma), Ziegler, A.-G. (Anette-G), Akolkar, B. (Beena), Norris, J. M. (Jill M.), Virtanen, S. M. (Suvi M.), Krischer, J. P. (Jeffrey P.), Agardh, D. (Daniel), Rewers, M. (Marian), Bautista, K. (Kimberly), Baxter, J. (Judith), Felipe-Morales, D. (Daniel), Driscoll, K. (Kimberly), Frohnert, B. I. (Brigitte, I), Gallant, M. (Marisa), Gesualdo, P. (Patricia), Hoffman, M. (Michelle), Karban, R. (Rachel), Norris, J. (Jill), Steck, A. (Andrea), Waugh, K. (Kathleen), Simell, O. G. (Olli G.), Adamsson, A. (Annika), Ahonen, S. (Suvi), Akerlund, M. (Mari), Hekkala, A. (Anne), Holappa, H. (Henna), Hyoty, H. (Heikki), Ikonen, A. (Anni), Ilonen, J. (Jorma), Jaminki, S. (Sinikka), Jokipuu, S. (Sanna), Karlsson, L. (Leena), Kahonen, M. (Miia), Knip, M. (Mikael), Koivikko, M.-L. (Minna-Liisa), Koreasalo, M. (Mirva), Kytola, J. (Jarita), Latva-aho, T. (Tiina), Lindfors, K. (Katri), Lonnrot, M. (Maria), Mantymaki, E. (Elina), Mattila, M. (Markus), Multasuo, K. (Katja), Mykkanenv, T. (Teija), Niininen, T. (Titha), Niinisto, S. (Sari), Nyblom, M. (Mia), Oikarinen, S. (Sami), Ollikainen, P. (Paula), Pohjola, S. (Sirpa), Rajala, P. (Petra), Rautanen, J. (Jenna), Riikonen, A. (Anne), Romo, M. (Minna), Ruohonen, S. (Suvi), Simell, S. (Satu), Sjoberg, M. (Maija), Stenius, A. (Aino), Tossavainen, P. (Paivi), Vaha-Makila, M. (Mari), Vainionpaa, S. (Sini), Varjonen, E. (Eeva), Veijola, R. (Riitta), Viinikangas, I. (Irene), Schatz, D. (Desmond), Hopkins, D. (Diane), Steed, L. (Leigh), Bryant, J. (Jennifer), Silvis, K. (Katherine), Haller, M. (Michael), Gardiner, M. (Melissa), Mclndoe, R. (Richard), Sharma, A. (Ashok), Anderson, S. W. (Stephen W.), Jacobsen, L. (Laura), Marks, J. (John), Towe, P. D. (P. D.), Ziegler, A. G. (Anette G.), Bonifacio, E. (Ezio), D'Angelo, M. (Miryam), Gavrisan, A. (Anita), Gezginci, C. (Cigdem), Heublein, A. (Anja), Hoffmann, V. (Verena), Hummel, S. (Sandra), Keimer, A. (Andrea), Knopff, A. (Annette), Koch, C. (Charlotte), Koletzko, S. (Sibylle), Ramminger, C. (Claudia), Roth, R. (Roswith), Scholz, M. (Marlon), Stock, J. (Joanna), Warncke, K. (Katharina), Wendel, L. (Lorena), Lernmark, A. (Ake), Ask, M. (Maria), Bremer, J. (Jenny), Cilio, C. (Corrado), Ericson-Hallstrom, E. (Emelie), Fors, A. (Annika), Fransson, L. (Lina), Gard, T. (Thomas), Bennet, R. (Rasmus), Hansen, M. (Monika), Hyberg, S. (Susanne), Jisser, H. (Hanna), Johansen, F. (Fredrik), Jonsdottir, B. (Berglind), Jovic, S. (Silvija), Larsson, H. E. (Helena Elding), Lindstrom, M. (Marielle), Lundgren, M. (Markus), Manson-Martinez, M. (Maria), Markan, M. (Maria), Melin, J. (Jessica), Mestan, Z. (Zeliha), Nilsson, C. (Caroline), Ottosson, K. (Karin), Rahmati, K. (Kobra), Ramelius, A. (Anita), Salami, F. (Falastin), Sjoberg, A. (Anette), Sjoberg, B. (Birgitta), Torn, C. (Carina), Wallin, A. (Anne), Wimar, A. (Asa), Aberg, S. (Sofie), Killian, M. (Michael), Crouch, C. C. (Claire Cowen), Akramoff, A. (Ashley), Chavoshi, M. (Masumeh), Dunson, K. (Kayleen), Hervey, R. (Rachel), Lyons, R. (Rachel), Meyer, A. (Arlene), Mulenga, D. (Denise), Radtke, J. (Jared), Romancik, M. (Matei), Schmitt, D. (Davey), Schwabe, J. (Julie), Zink, S. (Sarah), Becker, D. (Dorothy), Franciscus, M. (Margaret), Smith, M. D. (Maryellen Dalmagro-Elias), Daftary, A. (Ashi), Klein, M. B. (Mary Beth), Yates, C. (Chrystal), Austin-Gonzalez, S. (Sarah), Avendano, M. (Maryouri), Baethke, S. (Sandra), Brown, R. (Rasheedah), Burkhardt, B. (Brant), Butterworth, M. (Martha), Clasen, J. (Joanna), Cuthbertson, D. (David), Eberhard, C. (Christopher), Fiske, S. (Steven), Garmeson, J. (Jennifer), Gowda, V. (Veena), Heyman, K. (Kathleen), Hsiao, B. (Belinda), Karges, C. (Christina), Laras, F. P. (Francisco Perez), Lee, H.-S. (Hye-Seung), Li, Q. (Qian), Liu, S. (Shu), Lynch, K. (Kristian), Maguire, C. (Colleen), Malloy, J. (Jamie), McCarthy, C. (Cristina), Merrell, A. (Aubrie), Meulemans, S. (Steven), Parikh, H. (Hemang), Quigley, R. (Ryan), Remedios, C. (Cassandra), Shaffer, C. (Chris), Smith, L. (Laura), Smith, S. (Susan), Sulman, N. (Noah), Tamura, R. (Roy), Tewey, D. (Dena), Toth, M. (Michael), Vehik, K. (Kendra), Vijayakandipan, P. (Ponni), Wood, K. (Keith), Abbondondolo, M. (Michael), Ballard, L. (Lori), Hadley, D. (David), McLeod, W. (Wendy), Yu, L. (Liping), Miao, D. (Dongmei), Bingley, P. (Polly), Williams, A. (Alistair), Chandler, K. (Kyla), Ball, O. (Olivia), Kelland, I. (Ilana), Grace, S. (Sian), Hagopian, W. (William), Erlich, H. (Henry), Mack, S. J. (Steven J.), Fear, A. L. (Anna Lisa), Ke, S. (Sandra), Mulholland, N. (Niveen), Bourcier, K. (Kasia), Briese, T. (Thomas), Johnson, S. B. (Suzanne Bennett), and Triplett, E. (Eric)

Subjects
dietary supplements, probiotics, infant formula, celiac disease, celiac disease autoimmunity
Abstract

Probiotics are linked to positive regulatory effects on the immune system. The aim of the study was to examine the association between the exposure of probiotics via dietary supplements or via infant formula by the age of 1 year and the development of celiac disease autoimmunity (CDA) and celiac disease among a cohort of 6520 genetically susceptible children. Use of probiotics during the first year of life was reported by 1460 children. Time-to-event analysis was used to examine the associations. Overall exposure of probiotics during the first year of life was not associated with either CDA (n = 1212) (HR 1.15; 95%CI 0.99, 1.35; p = 0.07) or celiac disease (n = 455) (HR 1.11; 95%CI 0.86, 1.43; p = 0.43) when adjusting for known risk factors. Intake of probiotic dietary supplements, however, was associated with a slightly increased risk of CDA (HR 1.18; 95%CI 1.00, 1.40; p = 0.043) compared to children who did not get probiotics. It was concluded that the overall exposure of probiotics during the first year of life was not associated with CDA or celiac disease in children at genetic risk.

Published
2019

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