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2,400 results on '"Karlsson S"'

153. Multimodales, intraoperatives Neuromonitoring während chirurgischer Hüftgelenkluxation via Trochanter-Flip-Osteotomie

Author

Hesper, T, Scalone, B, Bittersohl, B, Karlsson, S, Keenan, J, and Hosalkar, H

Subjects
FAI, chirurgische Hüftgelenkluxation, ddc: 610, 610 Medical sciences, Medicine, Neuromonitoring
Abstract

Fragestellung: Nervenverletzungen stellen eine schwerwiegende Komplikation nach Hüftgelenkoperationen dar, die zu einem irreversiblen Funktionsverlust für den Patienten führen können. Auch nach der von Ganz beschriebenen chirurgischen Hüftgelenkluxation via Trochanter-Flip-Osteotomie[zum vollständigen Text gelangen Sie über die oben angegebene URL], Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2017)

Published
2017
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154. Deterioration of basic activities of daily living and their impact on quality of life across different cognitive stages of dementia: A European study

Author

Giebel, C.M., Sutcliffe, C., Stolt, M., Karlsson, S., Renom-Guiteras, A., Soto, M., Verbeek, H., Zabalegui, A., RightTimePlaceCare Consortium, the, Challis, D., Health Services Research, RS: CAPHRI School for Public Health and Primary Care, RS: CAPHRI - Innovations in Health Care for the Elderly, and RS: Academische Werkplaats Ouderenzorg

Subjects
Cross-Cultural Comparison, Male, Gerontology, Activities of daily living, Psychological intervention, Context (language use), Neuropsychological Tests, Quality of life, Surveys and Questionnaires, Activities of Daily Living, medicine, Humans, Dementia, Mental Competency, Functional ability, Aged, ta316, Aged, 80 and over, Psychiatric Status Rating Scales, Depression, ta3142, Middle Aged, medicine.disease, humanities, Europe, Psychiatry and Mental health, Clinical Psychology, Caregivers, Ethnopsychology, Severe dementia, Disease Progression, Quality of Life, Female, Independent Living, Geriatrics and Gerontology, Psychology, Psychopathology
Abstract

Background:Performing basic activities of daily living (ADLs) is one of the major difficulties encountered in dementia, which can have considerable negative impacts on the quality of life (QoL) of people with dementia (PwD). However, the extent to which basic ADL performance deteriorates across mild, moderate, and severe dementia is little examined and its impact, together with depression and neuropsychiatric behavior, upon QoL, is of considerable relevance across European countries.Methods:Data were drawn from people living in the community who were participants in a large-scale European study on transition from community living to care homes of PwD. PwD completed measures on cognitive functioning and QoL, and informal carers reported upon QoL, depressive symptomatology, psychopathology, and functional ability of the PwD.Results:ADL performance deteriorated differently for each activity. In particular, toileting, transfer, and feeding remained relatively intact throughout, whereas performance on bathing and dressing deteriorated to a greater extent from mild to severe dementia. It appears that continence was not affected by the stage of dementia with similar levels of impairment. Basic ADL performance impacted to different degrees on QoL across dementia stages and countries.Conclusions:Interventions aimed at maintaining independence or QoL need to target different ADLs across different dementia stages and perhaps also tailor interventions to the context of different countries. Findings contribute to the development of non-pharmaceutical interventions and governmental pledges to promote independence in dementia.

Published
2014
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160. An in vitro load evaluation of a conical implant system with 2 abutment designs and 3 different retaining-screw alloys.

Author

Erneklint C, Ödman P, Örtengren U, and Karlsson S

Abstract

PURPOSE: The aim of this in vitro study was to evaluate the load resistance in a conical implant system by comparing combinations of 2 different abutment head angles and 3 different retaining screw materials. MATERIALS AND METHODS: The retaining screw materials (titanium alloy, gold alloy, and commercially pure titanium) were tested with abutment-head angles of 20 degrees and 45 degrees. Six groups of 10 specimens each were prepared. An oblique (30-degree) compression test was performed in a Lloyd LRX universal testing machine with the abutment attached to a superstructure with a retaining screw. All specimens were loaded until fracture or permanent deformation occurred. The results were evaluated statistically with Wilcoxon signed rank test for variance distribution (P < .05 considered significant). RESULTS: There were statistically significant differences in load resistance between 20-degree and 45-degree abutments. The titanium screws (titanium alloy and commercially pure) in the 45-degree abutment group had almost equal mean values, while the gold alloy had a significantly lower value. In the 20-degree abutment group, significantly higher values were found with commercially pure titanium compared to titanium alloy and gold alloy, but the difference between the values for the gold and titanium alloys was not significant. DISCUSSION: The angulation of the abutment head played the most significant role in determining the amount of load withstood, but the material used for the screw was also relevant. CONCLUSION: A 45-degree abutment can be combined with a retaining screw of any of these materials to create a functional implant system. The test also substantiated that, irrespective of the retaining-screw material, a 20-degree abutment could resist loading forces of at least 900 N. [ABSTRACT FROM AUTHOR]

Published
2006

161. Structural, electrical, and optical properties of low-doped 4H–SiC chemical vapor deposited epitaxial layers.

Author

Kalinina, E., Kholujanov, G., Zubrilov, A., Solov’ev, V., Davydov, D., Tregubova, A., Sheglov, M., Kovarskii, A., Yagovkina, M., Violina, G., Pensl, G., Halle´n, A., Konstantinov, A., Karlsson, S., Rendakova, S., and Dmitriev, V.

Subjects
EPITAXY, CHEMICAL vapor deposition
Abstract

Results of complex studies of structural, optical, and electrical characteristics of 4H–SiC n-type low-doped epitaxial layers grown by the chemical vapor deposition (CVD) method are presented. Characteristics of CVD layers grown on commercial wafers with and without a thin (<0.1 μm) buffer layer grown by liquid phase epitaxy (LPE) between the commercial wafer and CVD epitaxial layer were compared. It has been shown that the LPE filling process caused a significant improvement in the structural quality of CVD layers. Cathodoluminescence (CL) data and electrical characteristics of Schottky barriers (SB) revealed that the LPE layer also made the concentration profiles of the uncompensated donors and recombination centers for holes as well as the hole diffusion lengths more uniform over the CVD layer. According to CL and secondary ion mass-spectroscopy measurements the presence of aluminum as an impurity was detected in initial commercial wafers, as well as having LPE and CVD epitaxial layers. Forward current–voltage characteristics of SBs formed on CVD layers with and without a LPE buffer layer followed an exponential relationship with an ideality factor of 1.04–1.06 over six to seven orders of magnitude in current density. A noticeable increase of the breakdown voltage was also observed in samples with a LPE layer. © 2001 American Institute of Physics. [ABSTRACT FROM AUTHOR]

Published
2001
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169. Immunological biomarkers correlate to survival in CAR19-treated patients

Author

Lövgren, Tanja, Wenthe, Jessica, Karlsson, S. C. Hannah, Gammelgård, Gustav, Essand, Magnus, Savoldo, Barbara, Dotti, Gianpietro, Höglund, Martin, Brenner, Malcolm K., Hagberg, Hans, Enblad, Gunilla, Loskog, Angelica, Lövgren, Tanja, Wenthe, Jessica, Karlsson, S. C. Hannah, Gammelgård, Gustav, Essand, Magnus, Savoldo, Barbara, Dotti, Gianpietro, Höglund, Martin, Brenner, Malcolm K., Hagberg, Hans, Enblad, Gunilla, and Loskog, Angelica

Published
2017

170. Assessment of plasma endostatin to predict acute kidney injury in critically ill patients.

Author

Mårtensson, J, Vaara, S T, Pettilä, V, Ala-Kokko, T, Karlsson, S, Inkinen, O, Uusaro, A, Larsson, Anders, Bell, M, Mårtensson, J, Vaara, S T, Pettilä, V, Ala-Kokko, T, Karlsson, S, Inkinen, O, Uusaro, A, Larsson, Anders, and Bell, M

Abstract

BACKGROUND: We evaluated whether plasma endostatin predicts acute kidney injury (AKI), need for renal replacement therapy (RRT), or death. METHODS: Prospective, observational, multicenter study from 1 September 2011 to 1 February 2012 with data from 17 intensive care units (ICUs) in Finland. RESULTS: A total of 1112 patients were analyzed. We measured plasma endostatin within 2 h of ICU admission. Early AKI (KDIGO stage within 12 h of ICU admission) was found in 20% of the cohort, and 18% developed late AKI (KDIGO criteria > 12 h from ICU admission). Median (IQR) admission endostatin was higher in the early AKI group, 29 (19.1, 41.9) ng/ml as compared to 22.4 (16.1, 30.1) ng/ml for the late AKI group, and 18 (14.0, 23.6) ng/ml for non-AKI patients (P < 0.001). Endostatin level increased with increasing KDIGO stage. Significantly higher endostatin levels were found in patients with sepsis as compared to those without. Predictive properties for AKI, RRT, and mortality were low with corresponding areas under the receiver operating characteristic curve (AUC) of 0.62, 0.67, and 0.59. Sensitivity analyses among patients with chronic kidney disease or sepsis did not improve the predictive ability of endostatin. Adding endostatin to a clinical AKI prediction model (illness severity score, urine output, and age) insignificantly changed the AUC from 0.67 to 0.70 (P = 0.14). CONCLUSIONS: Endostatin increases with AKI severity but has limited value as a predictor of AKI, RRT and 90-day mortality in patients admitted to ICU. Moreover, endostatin does not improve AKI risk prediction when added to a clinical risk model.

Published
2017
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171. Effect of the dissolution time into an acid hydrolytic solvent to taylor electrospun nanofibrous polycaprolactone scaffolds

Author

Universitat Politècnica de València. Departamento de Máquinas y Motores Térmicos - Departament de Màquines i Motors Tèrmics, Universitat Politècnica de València. Instituto de Tecnología de Materiales - Institut de Tecnologia de Materials, Generalitat Valenciana, European Regional Development Fund, Royal Institute of Technology, Suecia, Universitat Politècnica de València, Ministerio de Economía y Competitividad, Ministerio de Educación, Cultura y Deporte, Gil-Castell, O., Badia, J.D., Strömberg, E., Karlsson, S., Ribes-Greus, A., Universitat Politècnica de València. Departamento de Máquinas y Motores Térmicos - Departament de Màquines i Motors Tèrmics, Universitat Politècnica de València. Instituto de Tecnología de Materiales - Institut de Tecnologia de Materials, Generalitat Valenciana, European Regional Development Fund, Royal Institute of Technology, Suecia, Universitat Politècnica de València, Ministerio de Economía y Competitividad, Ministerio de Educación, Cultura y Deporte, Gil-Castell, O., Badia, J.D., Strömberg, E., Karlsson, S., and Ribes-Greus, A.

Abstract

[EN] The hydrolysis of the polycaprolactone (PCL) as a function of the dissolution time in a formic/acetic acid mixture was considered as a method for tailoring the morphology of nanofibrous PCL scaffolds. Hence the aim of this research was to establish a correlation between the dissolution time of the polymer in the acid solvent with the physicochemical properties of the electrospun nanofibrous scaffolds and their further service life behaviour. The physico-chemical properties of the scaffolds were assessed in terms of fibre morphology molar mass and thermal behaviour. A reduction of the molar mass and the lamellar thickness as well as an increase of the crystallinity degree were observed as a function of dissolution time. Bead-free fibres were found after 24 and 48 h of dissolution time with similar diameter distributions. The decrease of the fibre diameter distributions along with the apparition of beads was especially significant for scaffolds prepared after 72 h and 120 h of dissolution time in the acid mixture. The service life of the obtained devices was evaluated by means of in vitro validation under abiotic physiological conditions. All the scaffolds maintained the nanofibrous structure after 100 days of immersion in water and PBS. The molar mass was barely affected and the crystallinity degree and the lamellar thickness increased along immersion preventing scaffolds from degradation. Scaffolds prepared after 24 h and 48 h kept their fibre diameters whereas those prepared after 72 h and 120 h showed a significant reduction. This PCL tailoring procedure to obtain scaffolds that maintain the nanoscaled structure after such long in vitro evaluation will bring new opportunities in the design of long-term biomedical patches. (C) 2016 Elsevier Ltd. All rights reserved.

Published
2017

172. Effect of sisal and hydrothermal ageing on the dielectric behaviour of polylactide/sisal biocomposites

Author

Universitat Politècnica de València. Instituto de Tecnología de Materiales - Institut de Tecnologia de Materials, Universitat Politècnica de València. Departamento de Máquinas y Motores Térmicos - Departament de Màquines i Motors Tèrmics, Generalitat Valenciana, Prince of Songkla University, European Regional Development Fund, Royal Institute of Technology, Suecia, Ministerio de Economía y Competitividad, Badia, J.D., Reig-Rodrigo, P., TERUEL JUANES, ROBERTO, Kittikorn, T., Strömberg, E., Ek, M., Karlsson, S., Ribes-Greus, A., Universitat Politècnica de València. Instituto de Tecnología de Materiales - Institut de Tecnologia de Materials, Universitat Politècnica de València. Departamento de Máquinas y Motores Térmicos - Departament de Màquines i Motors Tèrmics, Generalitat Valenciana, Prince of Songkla University, European Regional Development Fund, Royal Institute of Technology, Suecia, Ministerio de Economía y Competitividad, Badia, J.D., Reig-Rodrigo, P., TERUEL JUANES, ROBERTO, Kittikorn, T., Strömberg, E., Ek, M., Karlsson, S., and Ribes-Greus, A.

Abstract

[EN] The dielectric properties of virgin polylactide (PLA) and its reinforced composites with different weight amounts of sisal fibres were assessed at broad temperature (from - 130 degrees C to 130 degrees C) and frequency ranges (from 10(-2)-10(7) Hz), before and after being subjected to accelerated hydrothermal ageing. The synergetic effects of both the loading of sisal and hydrothermal ageing were analysed by means of dielectric relaxation spectra. The relaxation time functions were evaluated by the Havriliak-Negami model, substracting the ohmic contribution of conductivity. The intramolecular and intermolecular relaxations were respectively analysed by means of Arrhenius and Vogel-Fulcher-Tammann-Hesse thermal activation models. The addition of fibre increased the number of hydrogen bonds, which incremented the dielectric permittivity and mainly hindered the non-cooperative relaxations of the biocomposites by increasing the activation energy. Hydrothermal ageing enhanced the formation of the crystalline phase at the so-called transcrystalline region along sisal. This fact hindered the movement of the amorphous PLA fraction, and consequently decreased the dielectric permittivity and increased the dynamic fragility. (C) 2017 Elsevier Ltd. All rights reserved.

Published
2017

173. Relevant factors for the eco-design of polylactide/sisal biocomposites to control biodegradation in soil in an end-of-life scenario

Author

Universitat Politècnica de València. Departamento de Máquinas y Motores Térmicos - Departament de Màquines i Motors Tèrmics, Universitat Politècnica de València. Instituto de Tecnología de Materiales - Institut de Tecnologia de Materials, Generalitat Valenciana, Prince of Songkla University, European Regional Development Fund, Royal Institute of Technology, Suecia, Ministerio de Economía y Competitividad, Badia, J.D., Strömberg, E., Kittikorn, T., Ek, M., Karlsson, S., Ribes-Greus, A., Universitat Politècnica de València. Departamento de Máquinas y Motores Térmicos - Departament de Màquines i Motors Tèrmics, Universitat Politècnica de València. Instituto de Tecnología de Materiales - Institut de Tecnologia de Materials, Generalitat Valenciana, Prince of Songkla University, European Regional Development Fund, Royal Institute of Technology, Suecia, Ministerio de Economía y Competitividad, Badia, J.D., Strömberg, E., Kittikorn, T., Ek, M., Karlsson, S., and Ribes-Greus, A.

Abstract

[EN] The eco-design considers the factors to prepare biocomposites under an end-of-life scenario. PLA/sisal biocomposites were obtained from amorphous polylactide and sisal loadings of 10, 20 and 30 wt% with and without coupling agent, and subjected to biodegradation in soil according to standard IS0846. Mass loss, differential scanning calorimetry and size-exclusion chromatography were used for monitoring biodegradation. A statistical factorial analysis based on the molar mass M-n, and crystallinity degree X-c pointed out the relevance and interaction of amount of fibre and use of coupling agent with the time of burial in soil., During the preparation of biocomposites, chain scission provoked a similar reduction of M-n, for coupled and non-coupled biocomposites. The amount of fibre was relevant for the increase of Xc due to the increase of nucleation sites. The coupling agent accelerated the evolution of both factors: reduction of M-n, and the consequent increase of Xc, mainly during biodegradation in soil. Both factors should be balanced to facilitate microbial assimilation of polymer segments, since bacterial digestion is enhanced by chain scission but blocked by the promotion of crystalline fractions. (C) 2017 Elsevier Ltd. All rights reserved.

Published
2017

178. ESICM LIVES 2016: part two

Author

Sivakumar, S., Taccone, F. S., Desai, K. A., Lazaridis, C., Skarzynski, M., Sekhon, M., Henderson, W., Griesdale, D., Chapple, L., Deane, A., Williams, L., Strickland, R., Lange, K., Heyland, D., Chapman, M., Rowland, M. J., Garry, P., Westbrook, J., Corkill, R., Antoniades, C. A., Pattinson, K. T., Fatania, G., Strong, A. J., Myers, R. B., Jermaine, C. M., Robertson, C. S., Rusin, C. G., Hofmeijer, J., Sondag, L., Tjepkema-Cloostermans, M. C., Beishuizen, A., Bosch, F. H., van Putten, M. J. A. M., Carteron, L., Patet, C., Solari, D., Oddo, M., Ali, M. A., Dias, C., Almeida, R., Vaz-Ferreira, A., Silva, J., Monteiro, E., Cerejo, A., Rocha, A. P., Elsayed, A. A., Abougabal, A. M., Beshey, B. N., Alzahaby, K. M., Pozzebon, S., Ortiz, A. Blandino, Cristallini, S., Lheureux, O., Brasseur, A., Vincent, J. L., Creteur, J., Hravnak, M., Yousef, K., Chang, Y., Crago, E., Friedlander, R. M., Abdelmonem, S. A., Tahon, S. A., Helmy, T. A., Meligy, H. S., Puig, F., Dunn-Siegrist, I., Pugin, J., Gupta, S., Govil, D., Srinivasan, S., Patel, S. J., N, J. K., Gupta, A., Tomar, D. S., Shafi, M., Harne, R., Arora, D. P., Talwar, N., Mazumdar, S., Papakrivou, E. E., Makris, D., Manoulakas, E., Tsolaki, B., Karadodas, B., Zakynthinos, E., Garcia, I. Palacios, Martin, A. Diaz, Encinares, V. Sanchez, Ibañez, M. Pachón, Montero, J. Garnacho, Labrador, G., Cangueiro, T. Cebrero, Poulose, V., Koh, J., Kam, J. W., Yeter, H., Kara, A., Aktepe, O., Topeli, A., Tsolakoglou, I., Intas, G., Stergiannis, P., Kolaros, A. A., Chalari, E., Athanasiadou, E., Martika, A., Fildisis, G., Faivre, V., Mengelle, C., Favier, B., Payen, D., Poppe, A., Winkler, M. S., Mudersbach, E., Schreiber, J., Wruck, M. L., Schwedhelm, E., Kluge, S., Zöllner, C., Tavladaki, T., Spanaki, A. M., Dimitriou, H., Kondili, E., Choulaki, C., Meleti, E., Kafetzopoulos, D., Georgopoulos, D., Briassoulis, G., la Torre, A. García-de, de la Torre-Prados, M. V., Tsvetanova-Spasova, T., Nuevo-Ortega, P., Rueda-Molina, C., Fernández-Porcel, A., Camara-Sola, E., Salido-Díaz, L., García-Alcántara, A., Meleti, D. E., Suberviola, B., Riera, J., Rellan, L., Sanchez, M., Robles, J. C., Lopez, E., Vicente, R., Miñambres, E., Santibañez, M., Le Guen, M., Moore, J., Mason, N., Windpassinger, M., Plattner, O., Mascha, E., Sessler, D. I., Research, Outcomes, Melia, U., Fontanet, J., van den Berg, J. P., Struys, M. M. R. F., Vereecke, H. E. M., Jensen, E. W., Rood, P. J. T., van de Schoor, F., van Tertholen, K., Pickkers, P., van den Boogaard, M., Beardow, Z. J., Redhead, H., Paramasivam, K., Numan, T., Kamper, A. M., Rood, P., Peelen, L. M., Zeman, P. M., Slooter, A. J., van Ewijk, C. E., Jacobs, G. E., Girbes, A. R. J., Myatra, S. N., Harish, M. M., Prabu, N. R., Siddiqui, S., Kulkarni, A. P., Divatia, J. V., Murbach, L. D., Leite, M. A., Osaku, E. F., Costa, C. R. L. M., Pelenz, M., Neitzke, N. M., Moraes, M. M., Jaskowiak, J. L., Silva, M. M. M., Zaponi, R. S., Abentroth, L. R. L., Ogasawara, S. M., Jorge, A. C., Duarte, P. A. D., Hernández-Sánchez, N., Sánchez-Hurtado, L. A., García-Guillen, F. J., Ñamendys-Silva, S. A., Maghsoudi, B., Emami, M., Khosravi, M. B., Zand, F., Tabatabaie, H. R., Masjedi, M., Sabetiyan, G., Mokri, A., Troubleyn, J., Diltoer, M., Jacobs, R., Nguyen, D. N., De Waele, E., De Regt, J., Honoré, P. M., Van Gorp, V., Spapen, H. D., Contreras, R. S., Toapanta, N. D., Moreno, G., Sabater, J., Torrado, H., Gonzalez, M., Marin, M., Farigola, E., Gonzalez, A., Fernandez, J., Vera, A., Gisbert, X., Juliá, C., Uya, J., Corral, L., Elias-Jones, I., Gemmell, L., MacKay, A., Randall, D., Adwaney, A., Blunden, M., Prowle, J. R., Kirwan, C. J., Thomas, N., Martin, A., Owen, H., Darwin, L., Conway, D., Atkinson, D., Sharman, M., Barbanti, C., Amour, J., Gaudard, P., Rozec, B., Mauriat, P., M’rini, M., Leger, P. L., Cambonie, G., Liet, J. M., Girard, C., Laroche, S., Damas, P., Assaf, Z., Loron, G., Lecourt, L., Pouard, P., Prowle, J.R., Kim, S. H., Na, S., Kim, J., Oh, S. Y., Jung, C. W., Yoo, S. H., Min, S. H., Chung, E. J., Lee, H., Lee, N. J., Lee, K. W., Suh, K. S., Ryu, H. G., Marshall, D. C., Goodson, R. J., Salciccioli, J. D., Shalhoub, J., Potter, E. K., Kirk-Bayley, J., Karanjia, N. D., Forni, L. G., Creagh-Brown, B. C., Bossy, M., Nyman, M., Tailor, A., Creagh-Brown, B., D’Antini, D., Spadaro, S., Valentino, F., Sollitto, F., Cinnella, G., Mirabella, L., Calvo, F. J. Redondo, Bejarano, N., Padilla, D., Baladron, V., Villajero, P., Villazala, R., Redondo, J., Yuste, A. S., Liu, J., Shen, F., Teboul, J. L., Anguel, N., Beurton, A., Bezaz, N., Richard, C., Monnet, X., Fossali, T., Colombo, R., Ottolina, D., Rossetti, M., Mazzucco, C., Marchi, A., Porta, A., Catena, E., Tollisen, K. H., Andersen, G. Ø., Heyerdahl, F., Jacobsen, D., de Waard, M. C., van IJzendoorn, M. C. O., Buter, H., Kingma, W. P., Navis, G. J., Boerma, E. C., Rulisek, J., Balik, M., Zacharov, S., Kim, H. S., Jeon, S. J., Namgung, H., Lee, E., Cho, Y. J., Lee, Y. J., Huang, A., Cioccari, L., Luethi, N., Mårtensson, J., Bellomo, R., Forsberg, M., Edman, G., Höjer, J., Forsberg, S., Freile, M. T. Chiquito, Hidalgo, F. N., Molina, J. A. Martinez, Lecumberri, R., Rosselló, A. Figuerola, Travieso, P. Medrano, Leon, G. Tuero, Sanchez, J. Gonzalez, Frias, L. Sahuquillo, Rosello, D. Balsells, Verdejo, J. A. Garcia, Serrano, J. A. Noria, Winterwerp, D., van Galen, T., Vazin, A., Karimzade, I., Zand, A., Ozen, E., Ekemen, S., Akcan, A., Sen, E., Yelken, B. Buyukkidan, Kureshi, N., Fenerty, L., Thibault-Halman, G., Erdogan, M., Walling, S., Green, R. S., Clarke, D. B., Briassoulis, P., Kalimeris, K., Ntzouvani, A., Nomikos, T., Papaparaskeva, K., Politi, E., Kostopanagiotou, G., Crewdson, K., Rehn, M., Weaver, A., Brohi, K., Lockey, D., Wright, S., Thomas, K., Baker, C., Mansfield, L., Stafford, V., Wade, C., Watson, G., Bryant, A., Chadwick, T., Shen, J., Wilkinson, J., Furneval, J., Henderson, A., Hugill, K., Howard, P., Roy, A., Bonner, S., Baudouin, S., Ramírez, C. Sánchez, Escalada, S. Hípola, Viera, M. A. Hernández, Santana, M. Cabrera, Balcázar, L. Caipe, Monroy, N. Sangil, Campelo, F. Artiles, Vázquez, C. F. Lübbe, Santana, P. Saavedra, Santana, S. Ruiz, Quintard, H., Bouzat, P., Wollersheim, T., Malleike, J., Haas, K., Carbon, N., Schneider, J., Birchmeier, C., Fielitz, J., Spuler, S., Weber-Carstens, S., Enseñat, L., Pérez-Madrigal, A., Saludes, P., Proença, L., Gruartmoner, G., Espinal, C., Mesquida, J., Huber, W., Eckmann, M., Elkmann, F., Gruber, A., Lahmer, T., Mayr, U., Herner, A., Schellnegger, R., Schmid, R. M., Ayoub, W., Samy, W., Esmat, A., Battah, A., Mukhtar, S., Mongkolpun, W., Cortés, D. Orbegozo, Cordeiro, C. P. R., Funcke, S., Groesdonk, H., Saugel, B., Wagenpfeil, G., Wagenpfeil, S., Reuter, D. A., Fernandez, M. M., Fernandez, R., Magret, M., González-Castro, A., Bouza, M. T., Ibañez, M., García, C., Balerdi, B., Mas, A., Arauzo, V., Añón, J. M., Ruiz, F., Ferreres, J., Tomás, R., Alabert, M., Tizón, A. I., Altaba, S., Llamas, N., Goligher, E C., Fan, E., Herridge, M., Vorona, S., Sklar, M., Dres, M., Rittayamai, N., Lanys, A., Urrea, C., Tomlinson, G., Reid, W. D., Rubenfeld, G. D., Kavanagh, B. P., Brochard, L. J., Ferguson, N. D., Neto, A. Serpa, de Abreu, M. Gama, Pelosi, P., Schultz, M. J., Guérin, C., Papazian, L., Reignier, J., Ayzac, L., Loundou, A., Forel, J. M., Rolland-Debord, C., Bureau, C., Poitou, T., Clavel, M., Perbet, S., Terzi, N., Kouatchet, A., Similowski, T., Demoule, A., Hunfeld, N., Trogrlic, Z., Ladage, S., Osse, R. 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T., Russ, M., Braun, W., Walter, M., Francis, R., Lachmann, B., Leonhardt, S., Landaverde-López, A., Canedo-Castillo, N. A., Esquivel-Chávez, A., Arvizu-Tachiquín, P. C., Baltazar-Torres, J. A., Cardoso, V., Krystopchuk, A., Castro, S., Melão, L., Firmino, S., Marreiros, A., Almaziad, S., Kubbara, A., Barnett, W., Nakity, R., Alamoudi, W., Altook, R., Tarazi, T., Fida, M., Safi, F., Assaly, R., Santini, A., Milesi, M., Maraffi, T., Pugni, P., Cavenago, M., Gattinoni, L., Protti, A., Perchiazzi, G., Borges, J. B., Bayat, S., Porra, L., Broche, L., Hedenstierna, G., Larsson, A., Roneus, A., Segelsjö, M., Vestito, M. C., Gremo, E., Nyberg, A., Castegren, M., Pikwer, A., Yoshida, T., Engelberts, D., Otulakowski, G., Katira, B., Post, M., Brochard, L., Amato, M. B. P., Koch, N., Hoellthaler, J., Mair, S., Phillip, V., Beitz, A., Baladrón, V., Villarejo, P., Steenstra, R. J., Banierink, H., Hof, J., van der Horst, I. C., Nijsten, M. W., Hoekstra, M., Sterz, F., Horvatits, K., Herkner, H., Kott, M., Zitta, K., Brandt, B., Schildhauer, C., Elke, G., Hummitzsch, L., Albrecht, M., González, L. Rey, Alonso, D. Cabestrero, Sánchez, R. de Pablo, Lucas, J. Higuera, Ferlitsch, A., Fauler, G., Trauner, M., Pischke, S., Fischer, L., Thaiss, F., Koch, M., Bangert, K., Lohse, A. W., Nashan, B., Sterneck, M., Faenza, S., Siniscalchi, A., Pierucci, E., Mancini, E., Ricci, D., Gemelli, C., Cuoghi, A., Magnani, S., Atti, M., Sotos, F., Cánovas, J., López, A., Burruezo, A., Torres, D., Herrera-Gutierrez, M. E., Barrueco-Francioni, J., Arias-Verdú, D., Lozano-Saez, R., Quesada-Garcia, G., Seller-Pérez, G., Figueiredo, A., Anzola, Y., Pereira, R., Bento, L., Lai, M., Deiana, M., Seller-Perez, G., Vardas, K., Ilia, S., Sertedaki, A., Charmadari, E., Stratakis, C. A., Briassouli, E., Goukos, D., Psarra, K., Botoula, E., Tsagarakis, S., Mageira, E., Routsi, C., Nanas, S., Campello, E., Radu, C. M., Su, H., Lam, Y. M., Willis, K., Pullar, V., Hubner, R. P., Tsang, J. L., de Guadiana-Romualdo, L. García, Rebollo-Acebes, S., Esteban-Torrella, P., Jiménez-Sánchez, R., Jiménez-Santos, E., Ortín-Freire, A., Hernando-Holgado, A., Albaladejo-Otón, M. D., Coelho, L., Rabello, L., Póvoa, P., Varis, E., Poukkanen, M., Jacob, S., Takala, J., Wilkman, E., Lundberg, O. H. M., Bergenzaun, L., Rydén, J., Rosenqvist, M., Melander, O., Chew, M. S., Kishihara, Y., Yasuda, H., Jimenez, R., Torrella, P. Esteban, Fernandez, A., Sanchez, S., Ortin, A., Prats, R. Guillamat, Aguilera, E., Marti, D., Fernandez, L., Ferrer, M., Lanziotti, V. S., Pulcheri, L., Ribeiro, M. O., Barbosa, A. P., e Silva, J. R. Lapa, Soares, M., Salluh, J. I. F., Marqués, M. Gil, Moreno, A. Puppo, Pizarraya, A. Gutierrez, Diaz, J. Pachón, Smani, Y., Connell, M. Mc, Zhang, L. A., Parker, R. S., Banerjee, I., Clermont, G., Norberg, E., Oras, J., Cuisinier, A., Maufrais, C., Payen, J. F., Nottin, S., Walther, G., Arib, S., Bilotta, F., Badenes, R., Rubulotta, F., Mirek, S., Monfort, B., Stazi, E., Roig, A. Lozano, Magnoni, S., Marando, M., Pifferi, S., Conte, V., Ortolano, F., Carbonara, M., Bertani, G., Scola, E., Cadioli, M., Triulzi, F., Colombo, A., Stocchetti, N., Rotzel, H. B., Lázaro, A. Serrano, Prada, D. Aguillón, Guimillo, M. Rodriguez, Piqueras, C. Sanchís, Guia, J. Romero, Simon, M. García, Arizmendi, A. Mesejo, Carratalá, A., El Maraghi, S., Yehia, A., Bakry, M., Shoman, A., Backes, F. N., Bianchin, M. M., Vieira, S. R. R., de Souza, A., Backes, A. N., Klein, C., Arunkumar, A. S., Lozano, A., Gallaher, C., Cattlin, S., Gordon, S., Picard, J., Fontana, V., Bond, O., Nobile, L., Mrozek, S., Delamarre, L., Capilla, F., Al-Saati, T., Fourcade, O., Dominguez-Berrot, A. M., Gonzalez-Vaquero, M., Vallejo-Pascual, M. E., Gupta, D., Ivory, B. D., Chopra, M., McCarthy, J., Felderhof, C. L., MacNeil, C., Maggiorini, M., Duska, F., Fumis, R. R. L., Junior, J. M. Vieira, Amarante, G., Skorko, A., Sanders, S., Aron, J., Kroll, R. J., Redfearn, C., Krishnan, P., Khalil, J. E., Kongpolprom, N., Gulia, V., Lourenço, E., Duro, C., Baptista, G., Alves, A., Arminda, B., Rodrigues, M., Hayward, J., Baldwin, F., Gray, R., Katinakis, P. A., Stijf, M., Ten Kleij, M., Jansen-Frederiks, M., Broek, R., de Bruijne, M., Spronk, P. E., Sinha, K., Luney, M., Palmer, K., Keating, L., Abu-Habsa, M., Bahl, R., Baskaralingam, N., Ahmad, A., Kanapeckaite, L., Bhatti, P., Glace, S., Jeyabraba, S., Lewis, H. F., Kostopoulos, A., Raja, M., West, A., Ely, A., Turkoglu, L. M., Zolfaghari, P., Baptista, J. P., Marques, M. P., Martins, P., Pimentel, J., Su, Y. C., Villacres, S., Stone, M. E., Parsikia, A., Medar, S., O’Dea, K. P., Porter, J., Tirlapur, N., Jonathan, J. M., Singh, S., Takata, M., McWhirter, E., Lyon, R., Hariz, M. L., Azmi, E., Alkhan, J., Movsisyan, V., Petrikov, S., Marutyan, Z., Aliev, I., Evdokimov, A., Antonucci, E., Merz, T., Hartmann, C., Calzia, E., Radermacher, P., Nußbaum, B., Huber-Lang, M., Gröger, M., Svoren-Jabalera, E., Davenport, E. E., Humburg, P., Knight, J., Hinds, C. J., Jun, I. J., Kim, W. J., Lee, E. H., Besch, G., Perrotti, A., Puyraveau, M., Baltres, M., Samain, E., Chocron, S., Pili-Floury, S., Plata-Menchaca, E. P., Sabater-Riera, J., Estruch, M., Boza, E., Toscana-Fernández, J., Bruguera-Pellicer, E., Ordoñez-Llanos, J., Pérez-Fernández, X. L., Cavaleiro, P., Tralhão, A., Arrigo, M., Lopes, J.-P., Lebrun, M., Cholley, B., PerezVela, J. L., MarinMateos, H., Rivera, J. J. Jimenez, Llorente, M. A. Alcala, De Marcos, B. Gonzalez, Fernandez, F. J. Gonzalez, Laborda, C. Garcia, Zamora, D. Fernandez, Delgado, J. C. Lopez, Imperiali, C., Dastis, M., Górka, J., Górka, K., Iwaniec, T., Frołow, M., Polok, K., Fronczek, J., Kózka, M., Musiał, J., Szczeklik, W., Sileli, M., Moursia, C., Maleoglou, H., Leleki, K., Uz, Z., Ince, Y., Papatella, R., Bulent, E., De Mol, B., Vicka, V., Gineityte, D., Ringaitiene, D., Norkiene, I., Sipylaite, J., Möller, C., Thomas-Rueddel, D. O., Vlasakov, V., Rochwerg, B., Theurer, P., Al Sibai, J. Zanabili, Camblor, P. Martinez, Fernandez, P. Alvarez, Gala, J. M. García, Guisasola, J. Silba, Tamura, T., Miyajima, I., Yamashita, K., Yokoyama, M., Dalampini, E., Nastou, M., Baddour, A., Ignatiadis, A., Asteri, T., Hathorn, K. E., Purtle, S. W., Viana, M. V., Tonietto, T. A., Gross, L. A., Costa, V. L., Tavares, A. L. J., Lisboa, B. O., Moraes, R. B., Vieira, S. R., Viana, L. V., Azevedo, M. J., Ceniccola, G. D., Pequeno, R. S. F., Holanda, T. P., Mendonça, V. S., Araújo, W. M. C., Carvalho, L. S. F., Segaran, E., Vickers, L., Brinchmann, K., Wignall, I., De Brito-Ashurst, I., del Olmo, R., Esteban, M. J., Vaquerizo, C., Carreño, R., Gálvez, V., Kaminsky, G., Nieto, B., Fuentes, M., De la Torre, M. A., Torres, E., Alonso, A., Velayos, C., Saldaña, T., Escribá, A., GRIP, J., Kölegård, R., Sundblad, P., Rooyackers, O., Naser, Ben, Jaziri, F., Jazia, A. Ben, Barghouth, M., Hentati, O., Skouri, W., El Euch, M., Mahfoudhi, M., Turki, S., Abdelghni, K. Ben, Abdallah, Ben, Maha, B. N. M., Lorente, M., Włudarczyk, A., Hałek, A., Bargouth, M., Bennasr, M., Abdelghani, K. Ben, Abdallah, T. Ben, Geenen, I. L., Parienti, J. J., Straaten, H. M. Oudemans-van, Shum, H. P., King, H. S., Chan, K. C., Yan, W. W., Londoño, J. Gonzalez, Cardenas, C. Lorencio, Pedrosa, M. Morales, Gubianas, C. Murcia, Bertolin, C. Fuster, Batllori, N. Vila, Sirvent, J. M., Mukhopadhyay, A., Chan, H. Y., Kowitlawakul, Y., Remani, D., Leong, C. S. F., Henry, C. J., Puthucheary, Z. A., Mendsaikhan, N., Begzjav, T., Lundeg, G., Dünser, M., Welsh, S. P., Guerra, E., Zerpa, M. C. l., Zechner, F., Berdaguer, F., Risso-Vazquez, A., Masevicius, F. D., Greaney, D., Magee, A., Fitzpatrick, G., Lugo-Cob, R. G., Tejeda-Huezo, B. C., Cano-Oviedo, A. A., Aydogan, M. S., Togal, T., Taha, A., Chai, H. Z., Kam, C., Razali, S. S. Yang, Sivasamy, V., Kuan, L. Y., Morales, M. A. Lopez, Pires, T., and Azevedo, L. C. P.

Subjects
Meeting Abstracts
Abstract

Introduction In addition to systemic hemodynamics, the management\ud of neurocritically ill patients is often informed by neuromonitoring. In\ud the absence of high-level evidence clinicians are often guided by personal\ud and local expertise. Little is known about practices as they pertain\ud to the use of such monitoring in patients with acute brain injury (ABI).\ud Objectives To investigate practices in bedside monitoring for ABI patients.\ud Particularly interested in differences among “neurointensivists”\ud (NIs; defined here as intensivists whose clinical practice is comprised\ud > 1/3 by neurocritical care) and other intensivists (OIs). Also, to\ud explore patterns specific to traumatic brain injury (TBI) and subarachnoid\ud hemorrhage (SAH), as well as preferences and availability of\ud particular technologies/devices.\ud Methods Electronic survey of 22 items including two case-based scenarios;\ud endorsed by SCCM (9,000 recipients) and ESICM (on-line\ud newsletter) in 2013. A sample size of 370 was calculated based on a\ud population of 10,000 physician members, a 5 % margin error, and\ud 95 % confidence interval. We summarized results using descriptive\ud statistics (proportions with 95 % confidence intervals). A chi-square\ud test was used to compare proportions of responses between NIs and\ud OIs with a significance p < 0.05.\ud Results There were 655 responders (66 % completion rate); 422(65 %)\ud were classified as OIs and 226(35 %) as NIs. More NIs follow\ud hemodynamic protocols for neurocritically-ill patients (56 % vs. 43 %, p\ud 0.001), in TBI (44.5 % vs. 33.3 %, p 0.007), and in SAH (38.1 % vs. 21.3 %,\ud p < 000.1). For delayed cerebral ischemia (DCI), more NIs target cardiac\ud index (CI) (35 % vs. 21 %, p 0.0001), and fluid responsiveness (62 % vs.\ud 53 %, p 0.03), use more bedside ultrasound (BUS) (42 % vs. 29 %, p\ud 0.005) and arterial waveform analysis (40 % vs. 29 %, p 0.02). For DCI\ud neuromonitoring, NIs use more angiography (57 % vs. 43 %, p 0.004),\ud TCD (46 % vs. 38 %, p 0.0001), and CTP (32 % vs.16 %, p 0.0001). For\ud CPP optimization in TBI, NIs use more arterial waveform analysis (45 %\ud vs. 35 %, p 0.019), and BUS (37 % vs. 27.7 %, p 0.023), while more OIs\ud monitor mixed venous oxygen saturation (54.1 % vs. 45 %, p 0.045). For\ud TBI neuromonitoring, NIs use more PbtO2 (28 % vs. 10 %, p 0.0001). In\ud the case scenario of raised ICP/low PbtO2, most employ analgosedation\ud (47 %) and osmotherapy (38 %). Fewer make use of preserved pressure\ud reactivity, particularly OIs (vasopressor use 23 % vs. 34 %, p 0.014).\ud Conclusions There is large heterogeneity in the use of monitoring protocols,\ud variables, and technologies/devices. “Neurointensivists” not only\ud employ more neuromonitoring but also more hemodynamic monitoring\ud in patients with acute brain injury. ICP/CPP remain the most commonly\ud followed neuro-variables in TBI patients, with low use of other\ud brain-physiology parameters, sugg

Published
2016

179. 'Kysehän on koko ihmisestä':vuosien 1935, 1950 ja 1970 steriloimis- ja kastroimislakien kehykset Helsingin Sanomissa

Author

Karlsson, S. (Sonja)

Subjects
Information Studies
Abstract

Tutkielmassani tutkin vuosien 1935, 1950 ja 1970 steriloimis- ja kastroimislakien kehyksiä Helsingin Sanomissa. Tutkimuksen aineisto koostuu 59 lehtijutusta. Olen kerännyt aineiston manuaalisesti mikrofilmeiltä kolmen ajallisen kiintopisteen ympäriltä. Ensimmäinen kiintopiste sijoittuu Suomen ensimmäisen steriloimislain säätämisajankohtaan. Suomen ensimmäistä steriloimislakia alettiin suunnitella 1920-luvulla ja se astui voimaan vuonna 1935. Vastaavia lakeja säädettiin eri puolilla läntistä maailmaa samoina vuosikymmeninä. Suomen ensimmäinen steriloimislaki oli luonteeltaan rotuhygieeninen ja se mahdollisti pakkosteriloinnit. Lain tavoitteena oli vähentää kelvottomaksi luokiteltujen ihmisten määrää yhteiskunnassa. Lisääntymisen estämistä pidettiin tehokkaana menetelmänä tavoitteen saavuttamiseksi, koska rotuhygieenikot uskoivat kelvottomuuden olevan perinnöllistä. Toinen ajallinen kiintopiste sijoittuu vuoteen 1950, jolloin pakkosterilointien määräämistä helpotettiin ja kastroimistoimenpiteet erotettiin steriloimislaista omaksi laikseen. Lakien painopiste siirtyi rotuhygieenisestä kontrollista kohti sosiaalista kontrollia ja lakien muutos osuu yhteen suomalaisen hyvinvointiyhteiskunnan sosiaaliturvan laajentamisen kanssa. Kolmas ajallinen kiintopiste on näiden pakkotoimenpiteiden poistaminen Suomen laista vuonna 1970. Tutkimusmenetelmänä tutkielmassani on Erving Goffmanin luoma kehysanalyysi. Kehysanalyysi on paljon käytetty metodi mediatutkimuksessa. Koko aineistosta kehysanalyysiin valitsin 38 lehtijuttua. Paikansin aineistosta kaksi pääkehystä, jotka nimesin yksilön eduksi ja yhteiskunnan eduksi. Kahdessa ensimmäisessä ajallisessa kiintopisteessä yhteiskunnan edun kehys on toista kehystä vahvempi. Viimeisessä kiintopisteessä yksilön edun kehys näkyy yhteiskunnan edun kehystä huomattavasti enemmän. Muutos kehysten esiintymisessä liittyy laajempaan muutokseen suomalaisessa yhteiskunnassa ja kulttuurissa. Pakkotoimenpiteet mahdollistavien lakien voimassaoloaikana Suomessa oli vallalla poliittinen filosofia, jonka mukaan yksilön etu oli aina alisteinen yhteiskunnan edun edessä. Toisen maailmansodan jälkeen asenteet ja julkinen mielipide alkoivat muuttua. Kaupungistumisen ja hiljattaisen seksuaalisen vapautumisen myötä perinteiset arvot alkoivat murtua. Pakkolakeja, jotka rajoittivat yksilön oikeutta päättää omasta kehostaan, ei nähty enää ajankohtaisiksi välineiksi suomalaisessa sosiaalipolitiikassa.

Published
2016

180. Tehohoito tarvitsee laajan päivystyksen sairaalan palvelut

Author

Ala-Kokko, T. (Tero), Karlsson, S. (Sari), Kuitunen, A. (Anne), Uusaro, A. (Ari), Bendel, S. (Stepani), Parviainen, I. (Ilkka), Soininen, L. (Leena), Varpula, T. (Tero), Pettilä, V. (Ville), Valtonen, M. (Mika), Loisa, P. (Pekka), Saarinen, K. (Kari), Kiviniemi, O. (Outi), Sjövall, S. (Sari), Reinikainen, M. (Matti), Laru-Sompa, R. (Raili), and Hovilehto, S. (Seppo)

Published
2016

181. Investigation of the solar wind-Moon interaction onboard Chandrayaan-1 mission with the SARA experiment

Author

Barabash, S., Anil Bhardwaj, Wieser, M., Sridharan, R., Kurian, T., Varier, S., Vijayakumar, E., Abhirami, V., Raghavendra, K. V., Mohankumar, S. V., Dhanya, M. B., Thampi, S., Kazushi, A., Andersson, H., Yoshifumi, F., Holmström, M., Lundin, R., Svensson, J., Karlsson, S., Daniele Piazza, R., and Wurz, P.

Subjects
Chandrayaan, solar wind, elemental composition, magnetic anomalies, Moon, energetic neutral atoms
Abstract

資料番号: PAIS08049000

Published
2009

188. Shielding an MCP Detector for a Space-Borne Mass Spectrometer Against the Harsh Radiation Environment in Jupiter’s Magnetosphere

Author

Lasi, D., primary, Tulej, M., additional, Meyer, S., additional, Luthi, M., additional, Galli, A., additional, Piazza, D., additional, Wurz, P., additional, Reggiani, D., additional, Xiao, H., additional, Marcinkowski, R., additional, Hajdas, W., additional, Cervelli, A., additional, Karlsson, S., additional, Knight, T., additional, Grande, M., additional, and Barabash, S., additional

Published
2017
Full Text
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189. The association between physical dependency and the presence of neuropsychiatric symptoms, with the admission of people with dementia to a long-term care institution: A prospective observational cohort study

Author

Risco, E., Cabrera, E., Jolley, D., Stephan, A., Karlsson, S., Verbeek, H., Saks, K., Hupli, M., Sourdet, S., Zabalegui, A., RightTimePlaceCare Consortium, the, Health Services Research, RS: CAPHRI School for Public Health and Primary Care, RS: CAPHRI - R1 - Ageing and Long-Term Care, and RS: Academische Werkplaats Ouderenzorg

Subjects
Informal caregivers, ALZHEIMERS-DISEASE, Long-term care, 8 EUROPEAN COUNTRIES, RISK-FACTORS, Dependency, Institutionalization, Dementia, ILLNESS, HOME, PREDICTORS, Home care, INTERVENTIONS
Abstract

Background: Dementia is a progressive neurological disorder that causes a high degree of dependency. This dependency has been defined as an increased need for assistance due to deterioration in cognition and physical functioning, and changes in behavior. Highly dependent people with dementia are more likely to be institutionalized. Objectives: To investigate the association between specific categories of physical dependency and the presence of neuropsychiatric symptoms in people with dementia admitted to a long-term care institution. Design: A prospective observational cohort study. Settings: Home care and long-term care institutions in eight European countries. Participants: People with dementia living at home but at risk of institutionalization and recently institutionalized people with dementia. Method: Baseline and 3-month follow-up interviews were performed between November, 2010 and April, 2012. The sample consisted of 116 recently institutionalized dementia sufferers and 949 people with dementia still living at home. Physical dependency was measured using the Katz Activity of Daily Living index, and neuropsychiatric symptoms were assessed through The Neuropsychiatric Inventory. Specific categories of dependency were analyzed by performing a logistic regression analysis. This followed examination of baseline characteristics to define the degree of physical dependency, as factors associated with institutionalization, and evaluation of the same characteristics at 3-month follow-up to detect changes in the degree of physical dependency and neuropsychiatric symptoms associated with recent admission to a long-term care institution. Results: Toileting, dressing and continence dependency was higher in institutionalized people than in those receiving home-care. Delusion, hallucination, agitation, anxiety, apathy, motor-disturbances, night-time behavior and eating disorders were also worse in the institutionalized. Logistic regression analysis showed that independent factors significantly associated with being recently institutionalized were toileting (odds ratio = 2.3; 95% confidence interval = 1.43-3.71) and motor disturbances (odds ratio = 1.81; 95% confidence interval = 1.15-2.87). Conclusions: This study supports the association between type and degree of physical dependency in people with dementia and long-term institutionalization. Institutionalization is associated with physical dependency and the presence of neuropsychiatric symptoms. (C) 2015 Elsevier Ltd. All rights reserved.

Published
2015

190. Care and Service at Home for Persons With Dementia in Europe

Author

Bökberg, C., Ahlström, G., Leino-Kilpi, H., Soto-Martin, M.E., Cabrera, E., Verbeek, H., Saks, K., Stephan, A., Sutcliffe, C., Karlsson, S., Health Services Research, RS: CAPHRI School for Public Health and Primary Care, RS: CAPHRI - R1 - Ageing and Long-Term Care, and RS: Academische Werkplaats Ouderenzorg

Subjects
Europe, Geriatrics, mental disorders, Humans, Social Support, Dementia, Delivery of Health Care, Home Care Services, Community Mental Health Services, Health Services Accessibility
Abstract

Purpose To describe available and utilized formal care and service at home for persons with dementia, from diagnosis to end-of-life stage, in eight European countries. DesignA descriptive cross-country design concerning eight European countries as a part of the European research project RightTimePlaceCare. MethodsThe research team in each country used a mapping system to collect country-specific information concerning dementia care and service system. The mapping system consists of 50 types of care and service activities. Sixteen of the 50 predefined activities concerning care and service at home were selected for this study and subdivided into three categories, following the stages of dementia. FindingsAvailability was reported to be higher than utilization, and the findings indicated more similarities than differences among the eight countries involved. Even though there were several available activities of basic care and services and healthcare interventions, they were utilized by few in most countries. Furthermore, specialized dementia care and services were sparsely available and even more sparsely utilized in the participating countries. ConclusionsThe findings indicated that persons with dementia in Europe received formal care and service on a general, basic level but seldom adjusted to their specific needs. Clinical RelevanceThis study describes the gap between service provision and utilization enabling nurses to develop individually adjusted care plans for persons with dementia during the progress of the disease. The findings do not include matters of quality of care or how to best organize effective care and services. However, the activities of care and services presented here should shed light on what room there is for improvement when it comes to enabling persons with dementia to go on living at home.

Published
2015

191. Domesticated escapees on the run: the second-generation monitoring programme reports the numbers and proportions of farmed Atlantic salmon in >200 Norwegian rivers annually.

Author

Glover, K A, Urdal, K, Næsje, T, Skoglund, H, Florø-Larsen, B, Otterå, H, Fiske, P, Heino, M, Aronsen, T, Sægrov, H, Diserud, O, Barlaup, B T, Hindar, K, Bakke, G, Solberg, I, Lo, H, Solberg, M F, Karlsson, S, Skaala, Ø, and Lamberg, A

Subjects
ATLANTIC salmon, AQUACULTURE, RIVERS, MARICULTURE, PRODUCTION methods, SALMON farming
Abstract

Norway is the world's largest producer of farmed Atlantic salmon and is home to ∼400 rivers containing wild salmon populations. Farmed escapees, a reoccurring challenge of all cage-based marine aquaculture, pose a threat to the genetic integrity, productivity, and evolutionary trajectories of wild populations. Escapees have been monitored in Norwegian rivers since 1989, and, a second-generation programme was established in 2014. The new programme includes data from summer angling, autumn angling, broodstock sampling, and snorkelling surveys in >200 rivers, and >25 000 scale samples are analysed annually. In 2014–2017, escapees were observed in two-thirds of rivers surveyed each year, and between 15 and 30 of the rivers had >10% recorded escapees annually. In the period 1989–2017, a reduction in the proportion of escapees in rivers was observed, despite a >6-fold increase in aquaculture production. This reflected improved escape prevention, and possibly changes in production methods that influence post-escape behaviour. On average, populations estimated to experience the greatest genetic introgression from farmed salmon up to 2014 also had the largest proportions of escapees in 2014–2017. Thus, populations already most affected are those at greatest risk of further impacts. These data feed into the annual risk-assessment of Norwegian aquaculture and form the basis for directing mitigation efforts. [ABSTRACT FROM AUTHOR]

Published
2019
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192. Enhancing Nurse/Physician Collaboration in Ethical Issues in Paediatric Oncology

Author

Glosli, H., Bartholdson, C., Broner, T., Hauge, H. F., Karlsson, S., Pergert, Pernilla, Poroddsdottir, S., Tornudd, L., Stigmar, J., Petersen, G., Glosli, H., Bartholdson, C., Broner, T., Hauge, H. F., Karlsson, S., Pergert, Pernilla, Poroddsdottir, S., Tornudd, L., Stigmar, J., and Petersen, G.

Published
2016

193. Intravascular ultrasound guidance is associated with lower mortality in patients undergoing stenting for unprotected left main coronary artery lesions compared to angiography-guided stent implantation

Author

Andell, P., Karlsson, S., Mohammad, M., Gotberg, M., James, Stefan, Jensen, J., Frobert, O., Angeras, O., Nilsson, J., Omerovic, E., Lagerqvist, Bo, Persson, J., Koul, S., Erlinge, D., Andell, P., Karlsson, S., Mohammad, M., Gotberg, M., James, Stefan, Jensen, J., Frobert, O., Angeras, O., Nilsson, J., Omerovic, E., Lagerqvist, Bo, Persson, J., Koul, S., and Erlinge, D.

Published
2016

194. Impact of hydrothermal ageing on the thermal stability, morphology and viscoelastic performance of PLA/sisal biocomposites

Author

Universitat Politècnica de València. Instituto de Tecnología de Materiales - Institut de Tecnologia de Materials, Universitat Politècnica de València. Escuela Técnica Superior de Ingeniería del Diseño - Escola Tècnica Superior d'Enginyeria del Disseny, Ministerio de Educación, Cultura y Deporte, Corporación de Fomento de la Producción, Chile, Generalitat Valenciana, Prince of Songkla University, Royal Institute of Technology, Suecia, Gil Castell, Óscar, Badía Valiente, José David, Kittikorn, T., Strömberg, E., Ek, Martina, Karlsson, S., Ribes Greus, María Desamparados, Universitat Politècnica de València. Instituto de Tecnología de Materiales - Institut de Tecnologia de Materials, Universitat Politècnica de València. Escuela Técnica Superior de Ingeniería del Diseño - Escola Tècnica Superior d'Enginyeria del Disseny, Ministerio de Educación, Cultura y Deporte, Corporación de Fomento de la Producción, Chile, Generalitat Valenciana, Prince of Songkla University, Royal Institute of Technology, Suecia, Gil Castell, Óscar, Badía Valiente, José David, Kittikorn, T., Strömberg, E., Ek, Martina, Karlsson, S., and Ribes Greus, María Desamparados

Abstract

The influence of the combined exposure to water and temperature on the behaviour of polylactide/sisal biocomposites coupled with maleic acid anhydride was assessed through accelerated hydrothermal ageing. The biocomposites were immersed in water at temperatures from 65 to 85 °C, between the glass transition and cold crystallisation of the PLA matrix. The results showed that the most influent factor for water absorption was the percentage of fibres, followed by the presence of coupling agent, whereas the effect of the temperature was not significant. Deep assessment was devoted to biocomposites subjected to hydrothermal ageing at 85 °C, since it represents the extreme degrading condition. The morphology and crystallinity of the biocomposites were evaluated by means of X-Ray diffraction (XRD) and field emission scanning electron microscopy (FE-SEM). The viscoelastic and thermal performance were assessed by means of dynamic mechanic thermal analysis (DMTA) and thermogravimetry (TGA). The presence of sisal generally diminished the thermal stability of the biocomposites, which was mitigated by the addition of the coupling agent. After composite preparation, the effectiveness of the sisal fibre was improved by the crystallisation of PLA around sisal, which increased the storage modulus and reduced the dampening factor. The presence of the coupling agent strengthened this effect. After hydrothermal ageing, crystallisation was promoted in all biocomposites therefore showing more fragile behaviour evidencing pores and cracks. However, the addition of coupling agent in the formulation of biocomposites contributed in all cases to minimise the effects of hydrothermal ageing.

Published
2016

195. Formal support for informal caregivers to older persons with dementia through the course of the disease: an exploratory, cross-sectional study

Author

Lethin, C, Leino-Kilpi, H, Roe, Brenda, Martin Soto, M, Saks, K, Stephan, A, Zwakhalen, S, Zabalegui, A, Karlsson, S, Lethin, C, Leino-Kilpi, H, Roe, Brenda, Martin Soto, M, Saks, K, Stephan, A, Zwakhalen, S, Zabalegui, A, and Karlsson, S

Abstract

Background: In European countries, knowledge about availability and utilization of support for informal caregivers caring for older persons (≥65 years) with dementia (PwD) is lacking. To be able to evaluate and develop the dementia support system for informal caregivers to PwD, a survey of European support systems and professionals involved is needed. The aim of this study was to explore support for informal caregivers to PwD in European countries. We investigated the availability and utilization of support in each of the participating countries, and the professional care providers involved, through the dementia disease. Methods: A mapping system was used in 2010–2011 to gather information about estimations of availability, utilization, and professional providers of support to informal caregivers caring for PwD. Data collected was representing each country as a whole. Results: There was high availability of counselling, caregiver support, and education from the diagnosis to the intermediate stage, with a decrease in the late to end of life stage. Utilization was low, although there was a small increase in the intermediate stage. Day care and respite care were highly available in the diagnosis to the intermediate stage, with a decrease in the late to end of life stage, but both types of care were utilized by few or no caregivers through any of the disease stages. Professionals specialized in dementia (Bachelor to Master’s degree) provided counselling and education, whereas caregiver support for informal caregivers and day care, respite care, and respite care at home were provided by professionals with education ranging from upper secondary schooling to a Master’s degree. Conclusions: Counselling, caregiver support, and education were highly available in European countries from diagnosis to the intermediate stage of the dementia disease, decreasing in the late/end of life stages but were rarely utilized. Countries with care systems based on national guidelines for dem

Published
2016

198. Lentiviral gene transfer into primary and secondary NOD/SCID repopulating cells

Author

Woods, Nb, Fahlman, C., Mikkola, H., Hamaguchi, S., Olsson, K., Zufferey, R., Sten Eirik Waelgaard Jacobsen, Trono, D., and Karlsson, S.

Subjects
Genetic Vectors, Graft Survival, Lentivirus, Immunology, Gene Transfer Techniques, Hematopoietic Stem Cell Transplantation, Antigens, CD34, Mice, SCID, Cell Biology, Hematology, Fetal Blood, Hematopoietic Stem Cells, Polymerase Chain Reaction, Biochemistry, Hematopoiesis, Immunophenotyping, Mice, Mice, Inbred NOD, Transduction, Genetic, HIV-1, Animals, Humans, Cell Lineage
Abstract

The ability of lentiviral vectors to transfer genes into human hematopoietic stem cells was studied, using a human immunodeficiency virus 1 (HIV-1)–derived vector expressing the green fluorescence protein (GFP) downstream of the phosphoglycerate kinase (PGK) promoter and pseudotyped with the G protein of vesicular stomatitis virus (VSV). High-efficiency transduction of human cord blood CD34+cells was achieved after overnight incubation with vector particles. Sixteen to 28 percent of individual colony-forming units granulocyte-macrophage (CFU-GM) colonies derived from cord blood CD34+ cells were positive by polymerase chain reaction (PCR) for the GFP gene. The transduction efficiency of SCID-repopulating cells (SRC) within the cord blood CD34+population was assessed by serial transplantation into nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice. When 400 000 cord blood CD34+ cells were transplanted into primary recipients, all primary and secondary recipients contained and expressed the transgene. Over 50% of CFU-GM colonies derived from the bone marrow of these primary and secondary recipients contained the vector on average as determined by PCR. Transplantation of transduced cells in limiting dilution generated GFP+ lymphoid and myeloid progeny cells that may have arisen from a single SRC. Inverse PCR analysis was used to amplify vector-chromosomal junctional fragments in colonies derived from SRC and confirmed that the vector was integrated. These results show that lentiviral vectors can efficiently transduce very primitive human hematopoietic progenitor and stem cells.

Published
2000
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199. Autism spectrum traits and visual processing in young adults with very low birth weight: the Helsinki Study of Very Low Birth Weight adults

Author

Wolford, E., primary, Pesonen, A.-K., additional, Heinonen, K., additional, Lahti, M., additional, Pyhälä, R., additional, Lahti, J., additional, Hovi, P., additional, Strang-Karlsson, S., additional, Eriksson, J. G., additional, Andersson, S., additional, Järvenpää, A.-L., additional, Kajantie, E., additional, and Räikkönen, K., additional

Published
2016
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