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1,018 results on '"John, Mathew"'

152. Laparoscopic Repair of a Right Paraduodenal Hernia

Author

John Mathew Manipadam, Lekha V., Vamsi Syamprasad, and Ramesh H.

Subjects
right paraduodenal hernia, laparoscopic repair, Surgery, RD1-811
Abstract

Laparoscopic repair of a right paraduodenal hernia has been described sparingly in literature. We present an account of how we laparoscopically repaired a right paraduodenal hernia along with a review of the current literature as regards the various techniques that have been attempted. With the patient in supine position, and with umbilical camera port and three 5 mm ports, we mobilized the cecum and ascending colon up to the third part of the duodenum, thereby widening the neck of the hernia sac in the Waldeyer fossa. This method is ideal for the less severe incomplete rotation presenting with right paraduodenal hernia where there are no Ladd's bands and there is no requirement for fetalization of the bowel.

Published
2018
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153. The Effect of Preoperative Biliary and Pancreatic Drainage on Postoperative Pancreatic Fistula: A Retrospective Cohort Study

Author

John Mathew Manipadam, Mahesh S., Jacob Mathew Kadamapuzha, and Ramesh H.

Subjects
preoperative biliary drainage, postoperative pancreatic fistula, pancreaticoduodenectomy, Surgery, RD1-811
Abstract

Abstract Background Surgeons and endoscopists welcome routine preoperative biliary drainage prior to pancreaticoduodenectomy despite evidence that it increases complications. Its effect on postoperative pancreatic fistula is variably reported in literature. Simultaneous biliary and pancreatic drainage is rarely performed for very selected indications and its effects on postoperative pancreatic fistula are largely unknown. Our aim was to analyze the same while eliminating confounding factors. Methods Retrospective single center cohort study of patients who underwent pancreaticoduodenectomy over the past 10 years for carcinoma obstructing the lower common bile duct. Patients who underwent biliary stenting alone, biliary and pancreatic stenting, and no stenting prior to pancreaticoduodenectomy were the three study cohort groups and their records were scrutinized for the incidence of postoperative pancreatic fistula. Results Sixty-two patients underwent biliary stenting alone, 5 patients underwent both biliary and pancreatic stenting, and 237 patients were not stented in the adenocarcinoma group without chronic pancreatitis. The pancreatic fistula rate was similar in the patients who underwent biliary stenting alone when compared with the group which was not stented. (24/62 versus 67/237, odds ratio [OR] =0.619, confidence interval (CI) =0.345–1.112, p = 0.121). However, the patients who underwent both biliary and pancreatic stenting had a significant increase in postoperative pancreatic fistula compared with the not stented (p = 0.003). By univariate and multivariate analysis using Firth logistic regression, pancreatic texture (OR = 1.205, CI = 0.103–2.476, p = 0.032) and the presence of a biliary and pancreatic stent (OR = 2.695, CI = 0.273–7.617, p = 0.027) were the significant factors affecting pancreatic fistula. Conclusion Preoperative biliary drainage alone has no significant influence on postoperative pancreatic fistula except when combined with pancreatic stenting. We need more such studies from other centers to confirm that the rare event of preoperative biliary and pancreatic stenting has indeed this harmful effect on healing of postoperative pancreatic anastomosis.

Published
2018
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155. Nasalance in Cochlear Implantees

Author

Swapna Sebastian, N Sreedevi, Anjali Lepcha, and John Mathew

Subjects
Speech Intelligibility, Nasal Air Pressure, Hearing Loss, Cochlear Implantation, Hearing Aid Users, Medicine, Otorhinolaryngology, RF1-547
Abstract

ObjectivesSpeech intelligibility is severely affected in children with congenital profound hearing loss. Hypernasality is a problem commonly encountered in their speech. Auditory information received from cochlear implants is expected to be far superior to that from hearing aids. Our study aimed at comparing the percentages of nasality in the speech of the cochlear implantees with hearing aid users and also with children with normal hearing.MethodsThree groups of subjects took part in the study. Groups I and II comprised 12 children each, in the age range of 4-10 years, with prelingual bilateral profound hearing loss, using multichannel cochlear implants and digital hearing aids respectively. Both groups had received at least one year of speech therapy intervention since cochlear implant surgery and hearing aid fitting respectively. The third group consisted of age-matched and sex-matched children with normal hearing. The subjects were asked to say a sentence which consisted of only oral sounds and no nasal sounds ("Buy baby a bib"). The nasalance score as a percentage was calculated.ResultsStatistical analysis revealed that the children using hearing aids showed a high percentage of nasalance in their speech. The cochlear implantees showed a lower percentage of nasalance compared to children using hearing aids, but did not match with their normal hearing peers.ConclusionThe quality of speech of the cochlear implantees was superior to that of the hearing aid users, but did not match with the normal controls. The study suggests that acoustic variables still exist after cochlear implantation in children, with hearing impairments at deviant levels, which needs attention. Further research needs to be carried out to explore the effect of the age at implantation as a variable in reducing nasality in the speech and attaining normative values in cochlear implantees, and also between unilateral versus bilateral implantees.

Published
2015
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157. Systemic Therapy in Thyroid Cancer

Author

Geethu Babu, R. Rejnish Ravi Kumar, Malu Rafi, Lekha M. Nair, Zuzaki Sharafuddin, John Mathew, Nijo Jose, and Cessal Thommachan Kainickal

Abstract

The standard treatment for patients with differentiated thyroid cancer (DTC) is a combination of surgery, radioactive iodine (RAI), and long-term thyroid hormone–suppression therapy. Treatment of patients whose diseases persist, recur, or metastasize remains a challenge. The role of cytotoxic chemotherapy in the treatment of thyroid cancer is limited. The key signaling pathways involved in the pathogenesis of thyroid cancers are the RAS/RAF/MEK & PI3K/Akt/mTOR pathways. Systemic therapy in thyroid cancer involves the use of tyrosine kinase inhibitors targeting the above mentioned pathways which are often both effective in controlling disease and have manageable toxicity. Sorafenib and lenvatinib are approved for advanced radioiodine refractory and poorly differentiated thyroid cancers and vandetanib and cabozantinib for recurrent or metastatic medullary thyroid cancers. Cabozantinib is also approved for the treatment of locally advanced or metastatic radioactive iodine–refractory differentiated thyroid cancer that has progressed after prior VEGF-targeted therapy. The combination of dabrafenib (BRAF inhibitor) and trametinib (MEK inhibitor) is approved for BRAF V600E mutated unresectable locally advanced anaplastic thyroid cancer. Selpercatinib, RET kinase inhibitor is used for advanced and metastatic RET mutated medullary thyroid cancers and advanced and metastatic RET fusion-positive thyroid cancers of any histologic type. Various clinical trials using newer molecules targeting the aforementioned pathways are ongoing.

Published
2022

158. Approach and Management of Anaplastic Carcinoma Thyroid

Author

Zuzaki Shabin, R. Rejnish Kumar, Malu Rafi, Lekha M. Nair, John Mathew, and Cessal Thommachan Kainickal

Abstract

Anaplastic carcinoma thyroid, also known as undifferentiated thyroid carcinoma, is a rare but highly aggressive malignant tumor, which accounts for 2–3% of all thyroid malignancies. It is mostly seen in elderly females in their 6th or 7th decade. It carries a very bad prognosis with an average median survival of 5 months. Patients often present with a rapidly growing, painful, woody hard lower anterior neck mass fixed to underlying structures. In addition to local invasion, patients also present with regional nodal spread and distant metastasis. Though the risk factors for anaplastic carcinoma thyroid are unknown, most of them develop in the setting of long-standing goiter, possibly in an undiagnosed, well-differentiated thyroid carcinoma. Management of anaplastic carcinoma thyroid demands a multidisciplinary approach with the involvement of surgeon, radiation oncologist, radiologist, and endocrinologist. The conventional treatment of anaplastic carcinoma thyroid includes surgery, radiation, and chemotherapy. Recently, multitarget tyrosine kinase inhibitors are also incorporated into the treatment. However, prognosis of the disease is very poor with 4 months of overall survival of 35% and overall disease-specific mortality of 98–99%. In this chapter, we discuss how to approach the condition and various treatment strategies to provide improved treatment outcomes for patients diagnosed with anaplastic carcinoma thyroid.

Published
2022

160. Four-decade-old benign tracheomediastinal fistula

Author

Jayakrishnan Soman Pillai, Nainar Madhu Sankar, Jovin John Mathew, Suchith Cheruvally, and Priya Baby

Subjects
Pulmonary and Respiratory Medicine, Surgery, Cardiology and Cardiovascular Medicine
Published
2022

162. Influence of different levels of dietary protein on serum biochemical parameters of dairy cows during the transition period

Author

S Nair Sreemol, K. Ally, V. Dildeep, John Mathew Jith, and V. L. Gleeja

Subjects
total mixed ration, Q1-390, dietary protein, Science (General), QP501-801, transition period, Animal biochemistry
Abstract

A study was carried out to find the influence of different dietary protein levels on serum biochemical parameters of dairy cows during the transition period. Twenty cross bred cows, three weeks prior to their expected date of calving were selected from University Livestock Farm and Fodder Research and Development Scheme (ULF&FRDS), College of Veterinary and Animal Sciences, Mannuthy as experimental animals. The cows were randomly allotted to two dietary treatments – T1 (12 per cent CP (crude protein) TMR (Total Mixed Ration)) and T2 (14 per cent CP TMR). After calving, half of the animals in T1 were allotted to T3 (16 per cent CP TMR) and remaining half to T4 (18 per cent CP TMR). Similarly half of the animals in T2 were allotted to T3 and remaining half to T4. All these rations were iso-caloric. The feeding trial was carried out for a period of 3 weeks prepartum and 45 days postpartum. The serum biochemical parameters such as serum glucose levels were significantly higher (p

Published
2021

163. Prevalence of HLA-B*27 subtypes in the Tamil population of India with Ankylosing spondylitis and its correlation with clinical features

Author

Snehil Kumar, Grace Rebekah, John Mathew, Dolly Daniel, Nitty Skariah Mathews, Debashish Danda, and R. Sam Arul Doss

Subjects
Adult, Male, 0301 basic medicine, medicine.medical_specialty, Immunology, Population, India, Disease, Dactylitis, 03 medical and health sciences, Sex Factors, 0302 clinical medicine, Gene Frequency, Internal medicine, Ethnicity, Prevalence, Humans, Immunology and Allergy, Medicine, Genetic Predisposition to Disease, Spondylitis, Ankylosing, Typing, education, HLA-B27 Antigen, Ankylosing spondylitis, education.field_of_study, business.industry, Enthesitis, General Medicine, medicine.disease, HLA-B, language.human_language, Phenotype, 030104 developmental biology, Tamil, language, Female, Joints, medicine.symptom, business, 030215 immunology
Abstract

Introduction HLA-B*27 is strongly associated with Ankylosing spondylitis (AS). Its subtypes show considerable geographic and ethnic difference. The main aim of this study was to assess the frequency of subtypes of HLA-B*27 in the Indian Tamil AS patients. Methods and materials Adult AS patients positive for HLA-B*27 were considered for the study. The high-resolution typing to define HLA-B*27 subtypes were done using Invitrogen B kits from One Lambda (SeCore® Sequencing Kits, Thermo Fisher, United States). Results and conclusion Prevalence of subtypes identified were HLA-B*27:04 (52.2%), HLA-B*27:05 (41.6%), HLA-B*27:07 (3.5%) and HLA-B*27:02 (2.7%). All subtypes showed disease predisposition for males. The most common extra articular manifestation seen was enthesitis in HLA-B*27:04 and HLA-B*27:05. Uveitis was mainly associated with HLA-B*27:05 and dactylitis with HLA-B*27:04. A significant peripheral joints involvement for female and axial joint involvement for males was seen in HLA-B*27:04. Our study establishes the prevalence of HLA-B*27 subtypes and the associated clinical phenotypes among the Indian Tamil population. Considering the variability of presentation, organ involvement, and disease course in different subtypes and across ethnicities it is critical to define these associations in the ethnic populations we treat for their appropriate care considering the significant negative health and socioeconomic effects of AS.

Published
2021

166. Pyoderma gangrenosum: A clinician′s nightmare

Author

Bindhu Bhaskaran, Mittu John Mathew, K N Vijayan, and Asha Zacharia

Subjects
Pyoderma gangrenosum, spreading, ulcer, Medicine
Abstract

Pyoderma gangrenosum (PG) is a rare disease and that affecting specifically the sole of the foot, is even rarer. Here, we report the case of a 54-year-old female admitted with a painful ulcer on the sole of the right foot which was initially treated with empirical antibiotics and debridement. The disease was found to spread rapidly after each debridement. The culture reports were negative; rheumatology workup and Doppler study were within normal limits. A clinical suspicion of PG was made and was confirmed with tissue biopsy. She was started on oral steroids following which she dramatically improved. Thus, when a patient presents with a rapidly expanding painful ulcer in a vascular limb that is refractory to antibiotic treatment and exacerbating on debridement, it is imperative to consider the possibility of PG.

Published
2016
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167. Outcomes of Percutaneous Intervention in Patients With Takayasu Arteritis

Author

George Joseph, Viji S. Thomson, Thomas V. Attumalil, Pratheesh G. Mathen, Arpudh M. Anandaraj, Oommen K. George, Paul V. George, Ruchika Goel, Sathish Kumar, John Mathew, and Debashish Danda

Subjects
Treatment Outcome, Humans, Stents, Cardiology and Cardiovascular Medicine, Takayasu Arteritis, Aneurysm, Angioplasty, Balloon, Retrospective Studies
Abstract

The status of vascular lesion treatment using percutaneous intervention (PI) in Takayasu arteritis (TAK) remains unresolved.This study sought to develop PI strategies appropriate for TAK.A prospectively maintained single-center database of TAK PI procedures from 1996 to 2022 was analyzed retrospectively. Obstructive lesions were treated by elective stenting (using bare or covered stents), balloon angioplasty (BA), or cutting-balloon angioplasty (CBA), with adjunctive stenting for suboptimal BA or CBA results. PIs were repeated in restenotic lesions until sustained success was obtained. Aortic or peripheral aneurysms and spontaneous aortic dissections were treated with covered stents or endografts. Immunosuppressive therapy, started before PI, was continued long term.A total of 942 patients underwent PI to treat 2,450 arterial lesions (2,365 stenoses or occlusions, 85 aneurysms or dissections) in 630 subclavian or axillary, 586 renal, 463 aortic, 333 carotid, 188 mesenteric, 116 iliac, 71 coronary, and 63 other arteries; 3,805 PIs were performed (1.55 PIs per lesion; range 1-7 PIs per lesion). Early success was obtained in 2,262 (92.3%), and late success in 1,460 (84.5%) of 1,727 lesions with a median of 39 months (IQR: 15-85 months) of follow-up. Repeated PIs increased late success in obstructive lesions from 48.6% to 83.3%. A total of 1,687 elective stenting lesions achieved 88% late success with 1.49 PIs per lesion; covered stents (1.18 PIs per lesion) restenosed less than bare stents (1.51 PIs per lesion; P 0.001). A total of 183 (36%) of 513 BA-treated lesions had good outcomes without adjunctive stenting; 122 CBA-treated lesions had 19% dissections and 8% ruptures or pseudoaneurysm formations. Aneurysms or dissections had 91.3% late success after PI. A total of 472 complications occurred in 415 (17%) lesions; 375 (79%) were resolved.Most vascular lesions in TAK can be effectively, safely, and durably treated using predominantly stent-based PI strategies.

Published
2022

168. Laparoscopic necrosectomy in acute necrotizing pancreatitis: Our experience

Author

Mittu John Mathew, Amit Kumar Parmar, Diwakar Sahu, and Prasanna Kumar Reddy

Subjects
Laparoscopic necrosectomy, necrotizing pancreatitis, retroperitoneal, transgastric, transluminal, Surgery, RD1-811, Diseases of the digestive system. Gastroenterology, RC799-869
Abstract

Context: Pancreatic necrosis is a local complication of acute pancreatitis. The development of secondary infection in pancreatic necrosis is associated with increased mortality. Pancreatic necrosectomy is the mainstay of invasive management. Aims: Surgical approach has significantly changed in the last several years with the advent of enhanced imaging techniques and minimally invasive surgery. However, there have been only a few case series related to laparoscopic approach, reported in literature to date. Herein, we present our experience with laparoscopic management of pancreatic necrosis in 28 patients. Materials And Methods: A retrospective study of 28 cases [20 men, 8 women] was carried out in our institution. The medical record of these patients including history, clinical examination, investigations, and operative notes were reviewed. The mean age was 47.8 years [range, 23-70 years]. Twenty-one patients were managed by transgastrocolic, four patients by transgastric, two patients by intra-cavitary, and one patient by transmesocolic approach. Results: The mean operating time was 100.8 min [range, 60-120 min]. The duration of hospital stay after the procedure was 10-18 days. Two cases were converted to open (7.1%) because of extensive dense adhesions. Pancreatic fistula was the most common complication (n = 8; 28.6%) followed by recollection (n = 3; 10.7%) and wound infection (n = 3; 10.7%). One patient [3.6%] died in postoperative period. Conclusions: Laparoscopic pancreatic necrosectomy is a promising and safe approach with all the benefits of minimally invasive surgery and is found to have reduced incidence of major complications and mortality.

Published
2014
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172. Management of Both Bones Forearm Fractures with Dynamic Compression Plate

Author

Jerson John Mathew, Jithin Jose Thomas, and Raja Nadar Chidambaram

Subjects
both bones, Medicine (General), R5-920, fixation, dynamic compression plate, fracture, Dentistry, RK1-715, forearm, diaphyseal
Abstract

Background: A study was conducted on Internal Fixation and Dynamic Compression Plating as management for both bones forearm diaphyseal fractures. Materials and Methods: This is a retrospective study in which 30 cases of diaphyseal fractures both bones forearm in adults were treated in Sree Balaji Medical College Hospital, Chennai .The average age ranged between 20-30 years .Fracture union, function and complications were assessed for the patients. Results: The grip strength and range of movements are good. Exceptional results were attained in 21cases (70%), good in 5 cases (17.5%), fair result in 4 cases (12.5%) . Occurrence of infection and delayed union were two and one cases respectively. Conclusion: Dynamic Compression Plating proves to be an effective treatment for both bone forearm fractures and choice of treatment is open reduction and internal fixation.

Published
2021

173. Mycophenolate in idiopathic inflammatory myositis: outcome data of a large South Asian cohort

Author

P. Chebbi, G. Arvind, Bijesh Yadav, John A. J. Prakash, Ashish J. Mathew, Grace Rebekah, John Mathew, Ruchika Goel, Aswin Nair, and Debashish Danda

Subjects
030203 arthritis & rheumatology, medicine.medical_specialty, business.industry, Interstitial lung disease, Retrospective cohort study, General Medicine, medicine.disease, Pericardial effusion, Rash, Gastroenterology, Rheumatology, Discontinuation, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Cohort, Inclusion and exclusion criteria, medicine, 030212 general & internal medicine, medicine.symptom, business
Abstract

Consensus on treatment of idiopathic inflammatory myositis (IIM), particularly with regard to flares and interstitial lung disease (ILD), does not exist. We studied the long-term outcome and treatment response in our large, retrospective cohort of adult South-Asian patients exclusively with IIM. Electronic records of IIM patients satisfying inclusion and exclusion criteria were studied longitudinally at presentation, at 3, 6, 12, 18 and 24 months and thereafter yearly till their last follow up (F/u) visit. Depending on clinical, imaging, and muscle enzyme profile during the F/u period, patients were categorised as complete (CR) and partial responders (PRs). Parameters favouring CR were assessed using multivariate logistic regression analysis. Outcome parameters and flares on immunosuppressants (IS) were then assessed in patients with/without ILD. Two hundred thirty-two patients with median F/u duration of 44.5 months (25–80.25) were included. ILD was seen in 40.1%. Patients with non-Jo1 anti-synthetase antibodies (n=26) were numerically more than those with Jo-1 antibody (n=24). CR status was attained by 50.9% patients. Absence of pericardial effusion (p=0.042, OR 4.223, 95% CI: 1.05–16.9) and presence of Gottron’s rash (p=0.044, OR 1.78, 95% CI 1.017–3.121) at baseline predicted CR by multivariate regression. Majority received mycophenolate during the entire F/u period. Discontinuation of steroids was feasible in 51.7% after a median duration of 24 months (18–42). After excluding patients with ILD, flares were numerically lesser in patients only on mycophenolate compared with those only on methotrexate (p=0.06). Further flares were curtailed when switched from other agents to mycophenolate. Mycophenolate is an effective treatment option in IIM patients with and without co-existing ILD. Presence of Gottron’s rash and absence of pericardial effusion were found to be predictors of favourable clinical outcome in this largest single-centre study.

Published
2021

174. A tale of two great mimickers: leprosy or sarcoidosis? A case-based review

Author

Reena Kharkele, John Mathew, RameshBabu Telugu, Shivraj Padiyar, and S Rima

Subjects
medicine.medical_specialty, business.industry, Diagnostic dilemma, Disease, Diseases of the musculoskeletal system, Radiological examination, medicine.disease, Dermatology, Rheumatology, RC925-935, medicine, uveitis, Leprosy, Sarcoidosis, sarcoidosis, business, granuloma, hansen's
Abstract

Leprosy and sarcoidosis are chronic multisystem disorders, with clinical features overlapping with each other. The diagnosis requires a thorough clinical, laboratory, histopathological, and radiological examination. Although it is possible to conclude on one particular diagnosis most of the time, in some cases, even after extensive evaluation, it is difficult to differentiate between the two diseases. In such scenarios, treating both the conditions is warranted. Here, we present a case with a diagnostic dilemma between Hansen's disease and sarcoidosis and systematically discuss the specific pointers which can help to differentiate between the two diseases.

Published
2021

175. Urinary vascular cell adhesion molecule-1 as a marker of disease activity in lupus nephritis

Author

John Mathew, Shivraj Padiyar, TheophilusS Vijayakumar, and Samuel Hansdak

Subjects
lupus nephritis, Cell adhesion molecule, business.industry, Urinary system, activity, Lupus nephritis, Diseases of the musculoskeletal system, medicine.disease, Disease activity, Rheumatology, RC925-935, medicine, Cancer research, systemic lupus erythematosus disease activity index, biomarker, business, urinary vascular cell adhesion molecule-11
Abstract

Objectives: The objective of this study is to study the role of urinary vascular cell adhesion molecule-1 (uVCAM-1) as a marker for disease activity in lupus nephritis (LN). Methodology: This was a diagnostic study where patients with active LN were taken as cases and those without LN were taken as disease controls. uVCAM-1 was correlated with the classes of LN and standard of care markers. Results: There was a significant difference between the uVCAM-1 values in cases (59.69 [range: 0.07–13752.5]) pg/mg and controls (2.11 [range − 0.11 − 1138.5] pg/mg [P = 0.02]). Maximum levels of VCAM 1 were seen in Class 4 and Class 5 LN (P = 0.96). Although higher renal systemic lupus erythematosus disease activity index score had a higher median value of uVCAM 1, the values were not statistically significant (P = 0.2). There is a positive correlation between the uVCAM1 and anti-double-stranded DNA (anti-dsDNA) levels (r = 0.38) and a negative correlation between VCAM 1 levels and C3 (r = −0.19).The sensitivity of uVCAM1 for determining the disease activity was 65.2%, and the specificity was 75% at a cutoff value of more than 23.8 pg/mg. Conclusions: uVCAM 1, although not in isolation, but along with the other standard of care markers may be useful in assessing the disease activity.

Published
2021

176. Zirconium-Doped Ceria Nanoparticles as Anticorrosion Pigments in Waterborne Epoxy–Polymer Coatings

Author

Sajith Vandana, Antony Joseph, and Kevin P. John Mathew

Subjects
Zirconium, Materials science, education, Doping, chemistry.chemical_element, Nanoparticle, Epoxy, humanities, Corrosion, Dielectric spectroscopy, Pigment, chemistry, Chemical engineering, visual_art, visual_art.visual_art_medium, Polymer coating, General Materials Science, sense organs
Abstract

The use of anticorrosion pigments in polymeric coatings is an effective way for the prevention of corrosion of metals. Ceria nanoparticle-based pigments are excellent replacement for conventional c...

Published
2020

177. Impact of the COVID-19 pandemic on patients with paediatric cancer in low-income, middle-income and high-income countries: a multicentre, international, observational cohort study

Author

Global Health Research Group on Children’s Non-Communicable Diseases Collaborative: Soham Bandyopadhyay, Noel, Peter, Kokila, Lakhoo, Simone de Campos Vieira Abib, Hafeez, Abdelhafeez, Shaun, Wilson, Max, Pachl, Benjamin, Martin, Sonal, Nagras, Mihir, Sheth, Catherine, Dominic, Suraj, Gandhi, Divya, Parwani, Rhea, Raj, Diella, Munezero, Rohini, Dutta, Nsimire Mulanga Roseline, Kellie, Mcclafferty, Armin, Nazari, Smrithi, Sriram, Sai, Pillarisetti, Kingdavid, Nweze, Aishwarya, Ashwinee, Gul, Kalra, Poorvaprabha, Patil, Priyansh, Nathani, Khushman Kaur Bhullar, Muhammed, Elhadi, Maryam, Khan, Nehal, Rahim, Shweta, Madhusudanan, Joshua, Erhabor, Manasi, Shirke, Aishah, Mughal, Darica, Au, Mahan, Salehi, Sravani, Royyuru, Mohamed, Ahmed, Syeda Namayah Fatima Hussain, Daniel, Robinson, Anna, Casey, Mehdi, Khan, Alexandre, Dukundane, Kwizera, Festus, Vaishnavi, Govind, Rohan, Pancharatnam, Lorraine, Ochieng, Elliott, H Taylor, Hritik, Nautiyal, Marta de Andres Crespo, Somy, Charuvila, Alexandra, Valetopoulou, Krithi, Ravi, Fatumata, Jalloh, Nermin, Badwi, Shahnur, Shah, Rohini, Rajpal, Masooma, Rana, Muskaan Abdul Qadir, Emmanuel, Uwiringiyimana, Abdelrahman, Azzam, Mayara, Fanelli, Gustavo Mendonça Ataíde Gomes, Igor Lima Buarque, Isadora Schwaab Guerini, Anfel, Bouderbala, Sarah, Alfurais, Mohamed, Gamal, Yara, Hijazi, Shatha, Tailakh, Hamza, Alnaggar, Zain, Douba, Sewar, Elejla, Abdullah, Eldaly, Ekram, Sharashi, Ahmad, Mansour, Tamara, Elyan, Aouabed, Nesrine, Ammar, Ayman, Aya, Zazo, Mohamed, Bonna, Safia, Lorabi, Hassan, Alalami, Rawan Yasser Emam, Soham, Bandyopadhyay, Muath, Alser, Mohamad, K Abou Chaar, Dennis, Mazingi, Hira, Zuberi, Iyad, Sultan, Dhruv Nath Ghosh, Nitin James Peters, Reto, M Baertschiger, Augusto, Zani, Lucy, Davies, Kefas John Bwala, M Umar, A, Abdurahaman, Aremu, Dauda, E Suleiman, Tybat, Aliyu, Ayesha, Saleem, Muhammad, Arshad, Kashaf, Turk, Sadaf, Altaf, Oluseyi Oyebode Ogunsua, Tunde Talib Sholadoye, Musliu Adetola Tolani, Yakubu, Alfa, Keffi Mubarak Musa, Mwangi, Irungu, Ken, Muma, Sarah, Muma, Mitchelle, Obat, Youssef Sameh Badran, Abdulrahman Ghassan Qasem, Faris, Ayasra, Reema, Alnajjar, Mohamed, Abdel-Maboud, Abdelrahman, Bahaa, Ayat, M Saadeldin, Mohamed, Adwi, Mahmoud, Adly, Abdallah, Elshenawy, Amer, Harky, Leanne, Gentle, Kirstie, Wright, Jessica, Luyt, Olivia, White, Charlotte, Smith, Nathan, Thompson, Thomas, Smith, Imogen, Harrison, Ashrarur Rahman Mitul, Sabbir, Karim, Nazmul, Islam, Sara Kader Alsaeiti, Fatma Saleh Benkhial, Mohammed Miftah Faraj Almihashhish, Eman Salem Muftah Burzeiza, Raja Mari Mohammed Nasef, Hend Mohammed Masoud, Mabroukah Saeid Alshamikh, Fatma Mohammed Masoud, William, B Lo, Nyararai, Togarepi, Elaine, Carrolan, Benjamin, J, Mohamed Hassanin O'Sullivan, Ahmed, Saleh, Mahmoud, Bassiony, Mostafa, Qatora, Mohamed, Bahaaeldin, Shady, Fadel, Yasmine El Chazli, Kamel, Hamizi, Mehdi Anouar Zekkour, Rima, Rahmoun, Boutheyna, Drid, Salma Naje Abu Teir, Mohamed Yazid Kadir, Yassine, Zerizer, Nacer, Khernane, Brahim, Saada, Imane, Ammouze, Yahya, Elkaoune, Hajar, Moujtahid, Ghita, Chaoui, Hajar, Benaouda, Meryem, Gounni, Narjiss, Aji, Laila, Hessissen, Joana Mafalda Monteiro, Susana, Nunes, Maria do Bom-Sucesso, Dave, R Lal, Brian, T Craig, Kerri, Becktell, Tahmina, Banu, Md Afruzul Alam, Orindom Shing Pulock, Tasmiah Tahera Aziz, Rosanda, Ilic, Danica, Grujicic, Tijana, Nastasovic, Igor, Lazic, Mihailo, Milicevic, Vladimir, Bascarevic, Radovan, Mijalcic, Vuk, Scepanovic, Aleksandar, Stanimirovic, Aleksandra, Paunovic, Ivan, Bogdanovic, Shahnoor, Islam, Akm Amirul Morshed, A K, M Khairul Basher, Mehnaz, Akter, M Rezanur Rahman, S, Zannat, Ara, Mohammed Tanvir Ahammed, Tania, Akter, Kamrun, Nahar, Fatema, Sayed, Ashfaque, Nabi, Md Asif Iqbal, Md Masud Rana, Asaduzzaman, Md, Hasanuzzaman, Md, Kemal Tolga Saracoglu, Elif, Akova, Evren, Aydogmus, Bekir Can Kendirlioglu, Tufan, Hicdonmez, Arshiya, Adhnon, Asim Noor Rana, Hani, Humad, Anjan, Madasu, Ahmed, Y Azzam, Mohammed, A Azab, Sherief, Ghozy, Alzhraa Salah Abbas, Olanrewaju, Moses, Ibiyeye Taiye Taibat, Taiwo, Jones, Kalu, Ukoha, Olagundoye, Goke, Okorie, Ikechukwu, Abiodun Idowu Okunlola, Milind, Chitnis, Helga, Nauhaus, Danelle, Erwee, Robyn, Brown, Agata, Chylinska, Robin, Simpson, Prasanna, Gomes, Marco Aurelio Ciriaco Padilha, Elvercio Pereira de Oliveira Junior, Lucas Garschagen de Carvalho, Fabiola Leonelli Diz, Mohamed El Kassas, Usama, Eldaly, Ahmed, Tawheed, Mohamed, Abdelwahab, Oudrhiri Mohammed Yassaad, Bechri, Hajar, El Ouahabi Abdessamad, Arkha, Yasser, Hessissen, Laila, Farah Sameer Yahya, Yasir, Al-Agele, Maria Teresa Peña Gallardo, Jacqueline Elizabeth Montoya Vásquez, Juan Luis García León, Sebastián Shu Yip, Mariam, Lami, Matthew H, V Byrne, Duha, Jasim, Harmit, Ghattaura, Eric, W Etchill, Daniel, Rhee, Stacy, Cooper, Kevin, Crow, Morgan, Drucker, Megan, Murphy, Benjamin, Shou, Alan, Siegel, Yasin, Kara, Gül Nihal Özdemir, Mahmoud, Elfiky, Ehab El Refaee, John George Massoud, Ayah Bassam Ibrahim, Ruaa Bassam Ibrahim, Faris Abu Za'nouneh, Ranya, M Baddourah, Toqa, Fahmawee, Ayah Al Shraideh, Ghazwani, Salman, Ehab, Alameer, Al-Mudeer, Ali, Ghazwani, Yahia, Khozairi, Waleed, Khalil, Ghandour, Shaima', Al-Dabaibeh, Ammar, Al-Basiti, Hazim, Ababneh, Omaima, El-Qurneh, Yousef, Alalawi, Ahmad Al Ayed, Ehab, Hanafy, Naif Al Bolowi, Amos Hp Loh, Anette, S Jacobsen, Heidi, Barola, Aubrey, L Pagaduan, Jingdan, Fan, Olumide Abiodun Elebute, Adesoji, O Ademuyiwa, Christopher, O Bode, Justina, O Seyi-Olajide, Oluwaseun, Ladipo-Ajayi, Felix, M Alakaloko, George, C Ihediwa, Kareem, O Musa, Edamisan, O Temiye, Olufemi, Oni, Adeseye, M Akinsete, Janita, Zarrish, Ramsha, Saleem, Soha, Zahid, Atiqa, Amirali, Ahsan, Nadeem, Sameer Saleem Tebha, Zonaira, Qayyum, Sana, Tahir, Anneqa, Tahir, Rabbey Raza Khan, Ayesha, Mehmood, Taimur Iftikhar Qureshi, Pooja, Kumari, Victor, Calvagna, Nathalie, Galea, Ariana, Axiaq, Matthew, R Schuelke, Jake, A Kloebe, Robert, L Owen, Alexander, S Roth, Catherine, Yang, J Hudson Barnett, Lucien, P Jay, Kirk David Wyatt, Paul, J Galardy, Agnes, Vojcek, Mahmoud Maher Abdelnaby Alrahawy, Seham, M Ragab, Abdallah, R Allam, Eman Ibrahim Hager, Kıvılcım Karadeniz Cerit, Adnan, Dağçınar, Tümay, Umuroğlu, Ayten, Saraçoğlu, Mustafa, Sakar, Can, Kıvrak, Gül, Çakmak, Ibrahim, Sallam, Gamal, Amira, Mohamed, Sherief, Ahmed, Sherif, Simone de Oliveira Coelho, Arissa, Ikeda, Licia, Portela, Marianne Monteiro Garrigo, Ricardo Vianna de Carvalho, Fernanda, Lobo, Sima Ester Ferman, Fernanda Ferreira da Silva Lima, Moawia Mohammed Ali Elhassan, Nada Osman Yousif Elhaj, Hytham K, S Hamid, Emmanuel, A Ameh, Vincent, E Nwatah, Adewumi, B Oyesakin, Andrew Nwankwo Osuigwe, Okechukwu Hyginus Ekwunife, Chisom Adaobi Nri-Ezedi, Eric Okechukwu Umeh, Nellie, Patiala, Ibukunolu Olufemi Ogundele, Abiodun Folashade Adekanmbi, Olubunmi Motunrayo Fatungase, Olubunmi Obafemi Obadaini, Sarah, Al-Furais, Humaida, Hemlae, Sreylis, Nay, John, Mathew, M Jeffri Ismail, R, Simonede Campos Vieira Abib, Fabianne Altruda de Moraes Costa Carlesse, Mayara Caroline Amorim Fanelli, Fernanda Kelly Marques de Souza, Pierfrancesco, Lapolla, Andrea, Mingoli, Denis, Cozzi, Anna Maria Testi, Paolo, Musiu, Paolo, Sapienza, Gioia, Brachini, Martina, Zambon, Simona, Meneghini, Pierfranco, Cicerchia, Bruno, Cirillo, Abdulrahman Omar Taha, Bouaoud, Souad, Mebarki, Malika, Bioud, Belkacem, Ayman, Meelad, Hajier Salim Alrashed, Fayza, Haider, Fatema Naser Al Fayez, Fakher, Rahim, Alhassan, Abdul-Mumin, Halwani Yaninga Fuseini, Peter Gyamfi Kwarteng, Abubakari Bawa Abdulai, Sheba Mary Pognaa Kunfah, Gilbert, B Bonsaana, Stephanie, Ajinkpang, Edmund, M Der, Francis, A Abantanga, Mary Joan Kpiniong, Kingsley Aseye Hattor, Kingsley Appiah Bimpong, Mohamed, Elbahnasawy, Sherief, Abdelsalam, Ahmed, Samir, Amanpreet, Brar, Andreea, C Matei, Lubna, Samad, Hira Khalid Zuberi, Kishwer, Nadeem, Naema, Khayyam, Fatima Ambreen Imran, Nida, Zia, Sadia, Muhammad, Muhammad Rafie Raza, Muhammad Rahil Khan, Alaa, Hamdan, Abdeljawad, Mazloum, Ali, Abodest, Nisreen, Ali, Bardisan, Gawarieh, Ammar, Omran, Almed, Moussa, Alaa, Ahmed, Munawar, Hraib, Victor, Khoury, Abdulrahman, Almjersah, Mohammad Ali Deeb, Almahmod, Alkhalil, Akram, Ahmed, Mohammad, Ahmad, Ali, Alelayan, Ali, Hammed, Wassem, Shater, Ahmad, Bouhuwaish, Alqasim, Abdulkarim, Eman, Abdulwahed, Marwa, Biala, Reem, Ghamgh, Amani, Alamre, Marwa, Shelft, Asmaa A, M Albanna, Hoda, Tawel, Emmanuel, Hatzipantelis, Athanasios, Tragiannidis, Eleni, Tsotridou, Assimina, Galli-Tsinopoulou, Dayang Anita Abdul Aziz, Zarina Abdul Latiff, Hamidah, Alias, C-Khai, Loh, Doris, Lau, Azrina Syarizad Khutubul, Raphael, N Vuille-Dit-Bille, Stefan, G Holland-Cunz, Nima, Allafi, Taiwo Akeem Lawal, Kelvin Ifeanyichukwu Egbuchulem, Olakayode Olaolu Ogundoyin, Isaac Dare Olulana, Biobele, J Brown, Oluwasegun Joshua Afolaranmi, Abdulbasit, Fehintola, Annika, Heuer, Christine, Nitschke, Michael, Boettcher, Matthias, Priemel, Lennart, Viezens, Martin, Stangenberg, Marc, Dreimann, Alonja, Reiter, Jasmin, Meyer, Leon, Köpke, Karl-Heinz, Frosch, Samson, Olori, Uduak, Offiong, Philip Mari Mshelbwala, Fashie Andrew Patrick, Aminu Muhammed Umar, N Otene ThankGod, Abdulrasheed, A Nasir, Kazeem O, O Ibrahim, Dupe, S Ademola-Popoola, Olayinka, T Sayomi, Alege, Abdurrzzaq, Ademola, A Adeyeye, Khadijah, O Omokanye, Lukman, O Abdur-Rahman, Olubisi Olutosin Bamidele, Shakirullah, Abdulazeez, Aminat, Akinoso, Michael, O Adegboye, Shireen Anne Nah, Yuki Julius Ng, Syukri Ahmad Zubaidi, Murad, Almasri, Sara, Ali, Rasaq, Olaosebikan, Akila, Muthukumar, Patricia, Shinondo, Amon, Ngongola, Bruce, Bvulani, Azad, Patel, Abdullahi, Nuhu-Koko, Baba, Jibrin, Ajiboye, L Olalekan, Christopher, S Lukong, Ezekiel, I Ajayi, Gabriela, Guillén, Sergio, López, José Andrés Molino, Pablo, Velasco, Omar, Elmandouh, Omar, Hamam, Rim, Elmandouh, Nensi Melissa Ruzgar, Rachel, Levinson, Shashwat, Kala, Sarah, Ullrich, Emily, Christison-Lagay, Aya Sabry Mortada, Mahmoud Ahmed Ebada, Eman Seif Alnaser Solimam, Khaled, Abualkher, Amr Mohammed Elsayed Yousf, Mohamed Mohamed Holail, Reem Mohamed Almowafy, Salah Eddine Oussama Kacimi, Janice Hui Ling Wong, Reto, Baertschiger, Essam, Elhalaby, Mahmoud, M Saad, Guido, Seitz, Judith, Lindbert, Francis Abantanga Georgios Tsoulfas, Asimina, Galli-Tsinopoulou, Maryam Ghavami Adel, Virgone, Calogero, Francesco, Pata, Gaetano, Gallo, Mohammad, K Abou Chaar, Eric Mwangi Irungu, Outani, Oumaima, Zineb, Bentounsi, Adesoji, Ademuyiwa, Lily, Saldana, Jan, Godzinsky, Abdelbasit, Ali, Dragana, Janic, Mohamed Bella Jalloh, Nellie, Bell, Annette, Jacobsen, Chan Hon Chui, Israel Fernandez Pineda, Lucas, Krauel, Maricarmen, Olivos, Waha, Rahama, Hazim, Elfatih, Arda, Isik, Kate, Cross, Andrea, Hayes-Jordan, Roshni, Dasgupta, Mohamedraed, Elshami, and Bandyopadhyay S., Peter N., Lakhoo K., Vieira Abib S. d. C. , Abdelhafeez H., Wilson S., Pachl M., Martin B., Nagras S., Sheth M., et al.

Subjects
Adolescent, Retinal Neoplasms, Temel Tıp Bilimleri, Medicine (miscellaneous), Assessment and Diagnosis, global surgery, Sağlık Bilimleri, Temel Bilgi ve Beceriler, Genel Tıp, Fundamental Medical Sciences, Pathophysiology, Clinical Medicine (MED), paediatrics, Cohort Studies, TIP, GENEL & DAHİLİ, Health Sciences, Internal Medicine, EPIDEMIOLOGY, Humans, Klinik Tıp (MED), Aile Sağlığı, Child, MEDICINE, GENERAL & INTERNAL, Developing Countries, Pandemics, Dahiliye, Patofizyoloji, paediatric oncology, public health, Developed Countries, COVID-19, Hodgkin Disease, Klinik Tıp, CHILDHOOD-CANCER, Fundamentals and Skills, General Medicine, CLINICAL MEDICINE, CARE, Değerlendirme ve Teşhis, Tıp, General Health Professions, Medicine, Tıp (çeşitli), Family Practice, Genel Sağlık Meslekleri
Abstract

ObjectivesPaediatric cancer is a leading cause of death for children. Children in low-income and middle-income countries (LMICs) were four times more likely to die than children in high-income countries (HICs). This study aimed to test the hypothesis that the COVID-19 pandemic had affected the delivery of healthcare services worldwide, and exacerbated the disparity in paediatric cancer outcomes between LMICs and HICs.DesignA multicentre, international, collaborative cohort study.Setting91 hospitals and cancer centres in 39 countries providing cancer treatment to paediatric patients between March and December 2020.ParticipantsPatients were included if they were under the age of 18 years, and newly diagnosed with or undergoing active cancer treatment for Acute lymphoblastic leukaemia, non-Hodgkin’s lymphoma, Hodgkin lymphoma, Wilms’ tumour, sarcoma, retinoblastoma, gliomas, medulloblastomas or neuroblastomas, in keeping with the WHO Global Initiative for Childhood Cancer.Main outcome measureAll-cause mortality at 30 days and 90 days.Results1660 patients were recruited. 219 children had changes to their treatment due to the pandemic. Patients in LMICs were primarily affected (n=182/219, 83.1%). Relative to patients with paediatric cancer in HICs, patients with paediatric cancer in LMICs had 12.1 (95% CI 2.93 to 50.3) and 7.9 (95% CI 3.2 to 19.7) times the odds of death at 30 days and 90 days, respectively, after presentation during the COVID-19 pandemic (pConclusionsThe COVID-19 pandemic has affected paediatric oncology service provision. It has disproportionately affected patients in LMICs, highlighting and compounding existing disparities in healthcare systems globally that need addressing urgently. However, many patients with paediatric cancer continued to receive their normal standard of care. This speaks to the adaptability and resilience of healthcare systems and healthcare workers globally.

Published
2022

178. Cardiovascular risk in newly diagnosed type 2 diabetes patients in India

Author

Unnikrishnan, A. G., primary, Sahay, R. K., additional, Phadke, Uday, additional, Sharma, S. K., additional, Shah, Parag, additional, Shukla, Rishi, additional, Viswanathan, Vijay, additional, Wangnoo, S. K., additional, Singhal, Santosh, additional, John, Mathew, additional, Kumar, Ajay, additional, Dharmalingam, Mala, additional, Jain, Subodh, additional, Shaikh, Shehla, additional, and Verberk, Willem J., additional

Published
2022
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181. Pregnancy and Diabetes

Author

Finny, Philip, primary, Jeyaraman, Kanakamani, additional, John, Mathew, additional, DM, Mahesh, additional, and K, Senthil, additional

Published
2016
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182. Endoscopic Repair of CSF Fistulae: A Ten Year Experience

Author

Arun Alexander, John Mathew, Ajoy Mathew Varghese, and Sivaraman Ganesan

Subjects
endoscopic sinus surgery, fovea ethmoidalis, lumbar drain, Medicine
Abstract

Introduction: Cerebrospinal Fluid (CFF) fistulae are repaired endoscopically with varying degrees of success around the world. Large series are still uncommon, and the results varied primarily because of the different techniques by different surgeons and also because of a variation in the patient profile in each series, for example, many series deal primarily with traumatic CSF leaks where the defects are larger and outcomes poorer. Aim: To analyse the surgical outcomes of Endoscopic CSF rhinorrhea closure. Materials and Methods: This is a series of 34 cases operated upon primarily by one surgeon in two different centres over a period of 10 years. Results: Of the 34 cases, 76% of the patients were women. Among the patients only 20.6% patients had a history of trauma preceding the CSF leak. The most common site of leak was in the fovea ethmoidalis in 19 (55.8%) followed by 10 (29.4%) in the cribriform plate. An overlay technique of placing the multiple layers of fascia and mucosa was used in 26 (76.5%) patients and underlay technique in the remaining. Postoperative lumbar drain was used in all patients. Conclusion: Based on the treatment outcome of the 34 patients, it can be concluded that the success rate of a single endoscopic procedure in our experience is 97% and 100% following the second. Endoscopic approach for closure of CSF leak is safe with minimal complications and little morbidity.

Published
2016
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183. Perforated Gastric Gangrene without Pneumothorax in an Adult Bochdalek Hernia due to Volvulus

Author

John Mathew Manipadam, George Mathew Sebastian, Venugopal Ambady, and Ramesh Hariharan

Subjects
duodenal ulcer perforation, laparotomy, organoaxial volvulus, Medicine
Abstract

Bochdalek hernia is the most frequent congenital diaphragmatic hernia which occurs due to a defect in the posterior attachment of the diaphragm when there is a failure of closure of the pleuroperitoneal membrane in utero. It rarely presents for the first time in adults. We report one such case of a 23-year-old male patient who presented with an acute abdomen. Chest X-ray showed air under diaphragm and he was taken up for an emergency laparotomy. Intraoperatively an organoaxial volvulus of the stomach was found in a bochdaleks hernia with a focal gangrene of the stomach fundus with perforation and peritonitis. However, there was no breach of pleural cavity. A sleeve resection of the gangrenous portion of the stomach was performed and the diaphragmatic defect was repaired. Patient made an uneventful postoperative recovery. Gastric gangrene with perforation as a manifestation of the adult bochdalek hernia is indeed rare. A concomitant pneumothorax occurs along with this condition which requires an intercostal drainage tube prior to the laparotomy. We report this case for its unique presentation without pneumothorax.

Published
2016
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184. USERS’ SURVEY FOR DEVELOPMENT OF PASSENGER DRONES

Author

Priyabrata Rautray, Deepak John Mathew, and Boris Eisenbart

Subjects
020301 aerospace & aeronautics, Emerging technologies, business.industry, media_common.quotation_subject, 0211 other engineering and technologies, 02 engineering and technology, General Medicine, User centred design, Drone, Megacity, Mode (computer interface), 0203 mechanical engineering, Industrial design, Business, Prosperity, Telecommunications, 021106 design practice & management, media_common
Abstract

The prosperity of any megacities heavily depends on smooth transport systems. In India, however, most cities are failing to keep in step with the growing demands. With new technologies, such as passenger drones, an alternate mode of intra-city transportation seems within reach. For successful development of passenger drones in a diverse country like India, understanding users’ needs are vital. This paper presents the results from a survey of potential users of passenger drones from across India. These are then used to derive concrete recommendations for passenger drones design parameters.

Published
2020

187. Twelve-month observational study of children with cancer in 41 countries during the COVID-19 pandemic

Author

Soham, Bandyopadhyay, Noel, Peter, Kokila, Lakhoo, Simone de Campos Vieira Abib, Hafeez, Abdelhafeez, Shaun, Wilson, Max, Pachl, Benjamin, Martin, Sonal, Nagras, Mihir, Sheth, Catherine, Dominic, Suraj, Gandhi, Divya, Parwani, Rhea, Raj, Diella, Munezero, Rohini, Dutta, Nsimire Mulanga Roseline, Kellie, Mcclafferty, Armin, Nazari, Smrithi, Sriram, Sai, Pillarisetti, King-David, Nweze, Aishwarya, Ashwinee, Gul, Kalra, Poorvaprabha, Patil, Priyansh, Nathani, Khushman Kaur Bhullar, Muhammed, Elhadi, Maryam, Khan, Nehal, Rahim, Shweta, Madhusudanan, Joshua, Erhabor, Manasi, Shirke, Aishah, Mughal, Darica, Au, Mahan, Salehi, Sravani, Royyuru, Mohamed, Ahmed, Syeda Namayah Fatima Hussain, Daniel, Robinson, Anna, Casey, Mehdi, Khan, Alexandre, Dukundane, Kwizera, Festus, Vaishnavi, Govind, Rohan, Pancharatnam, Lorraine, Ochieng, Elliott, H Taylor, Hritik, Nautiyal, Marta deAndres Crespo, Somy, Charuvila, Alexandra, Valetopoulou, Amanpreet, Brar, Hira, Zuberi, Imane, Ammouze, Dhruva, Ghosh, Nitin James Peters, Kefas John Bwala, M Umar, A, Abdurahaman, Aremu, Dauda, E Suleiman, Tybat, Aliyu, Ayesha, Saleem, Muhammad, Arshad, Kashaf, Turk, Sadaf, Altaf, Oluseyi Oyebode Ogunsua, Tunde Talib Sholadoye, Musliu Adetola Tolani, Yakubu, Alfa, Keffi Mubarak Musa, Eric Mwangi Irungu, Ken, Muma, Sarah, Muma, Mitchelle, Obat, Youssef Sameh Badran, Abdulrahman Ghassan Qasem, Faris, Ayasra, Reema, Alnajjar, Mohamed, Abdel-Maboud, Abdelrahman, Bahaa, Ayat, M Saadeldin, Mohamed, Adwi, Mahmoud, Adly, Abdallah, Elshenawy, Amer, Harky, Leanne, Gentle, Kirstie, Wright, Jessica, Luyt, Olivia, White, Charlotte, Smith, Nathan, Thompson, Thomas, Smith, Imogen, Harrison, Santosh Kumar Mahalik, Rajat, Piplani, Enono, Yhoshu, Manoj, Gupta, Uttam Kumar Nath, Amit, Sehrawat, S Rajkumar, K, Vivek, Singh, Sadi, A Abukhalaf, Ashrarur Rahman Mitul, Sabbir, Karim, Nazmul, Islam, Sara Kader Alsaeiti, Fatma Saleh Benkhial, Mohammed Miftah Faraj Almihashhish, Eman Salem Muftah Burzeiza, Hend Mohammed Masoud, Mabroukah Saeid Alshamikh, Raja Mari Mohammed Nasef, Fatma Mohammed Masoud, William, B Lo, Nyararai, Togarepi, Elaine, Carrolan, Benjamin, J O'Sullivan, Mohamed, Hassanin, Ahmed, Saleh, Mahmoud, Bassiony, Mostafa, Qatora, Mohamed, Bahaaeldin, Shady, Fadel, Yasmine El Chazli, Anfel, Bouderbala, Kamel, Hamizi, Safia, Lorabi, Mehdi Anouar Zekkour, Rima, Rahmoun, Boutheyna, Drid, Salma Naje Abu Teir, Mohamed Yazid Kadir, Yassine, Zerizer, Nacer, Khernane, Brahim, Saada, Yahya, Elkaoune, Hajar, Moujtahid, Ghita, Chaoui, Hajar, Benaouda, Meryem, Gounni, Narjiss, Aji, Laila, Hessissen, Joana Mafalda Monteiro, Susana, Nunes, Maria do Bom-Sucesso, Dave, R Lal, Brian, T Craig, Kerri, Becktell, Tahmina, Banu, Md Afruzul Alam, Orindom Shing Pulock, Tasmiah Tahera Aziz, Vishal, Michael, M Joseph John, William, Bhatti, Bobby, John, Swati, Daniel, Jyoti, Dhiman, Hunar, Mahal, Atul, Suroy, Rosanda, Ilic, Danica, Grujicic, Tijana, Nastasovic, Igor, Lazic, Mihailo, Milicevic, Vladimir, Bascarevic, Radovan, Mijalcic, Vuk, Scepanovic, Aleksandar, Stanimirovic, Aleksandra, Paunovic, Ivan, Bogdanovic, Shruti, Kakkar, Shaina, Kamboj, Suraj, Singh, Shahnoor, Islam, Akm Amirul Morshed, Akm Khairul Basher, Mehnaz, Akter, M Rezanur Rahman, S, Zannat, Ara, Mohammed Tanvir Ahammed, Tania, Akter, Kamrun, Nahar, Fatema, Sayed, Ashfaque, Nabi, Md Asif Iqbal, Md Masud Rana, Asaduzzaman, Md, Hasanuzzaman, Md, Kemal Tolga Saracoglu, Elif, Akova, Evren, Aydogmus, Bekir Can Kendirlioglu, Tufan, Hicdonmez, Ahmed, Y Azzam, Mohammed, A Azab, Sherief, Ghozy, Alzhraa Salah Abbas, Monica, Dobs, Mohamed Atef Mohamed Ghamry, Mohammed, Alhendy, Joana, Monteiro, Olanrewaju, Moses, Ibiyeye Taiye Taibat, Taiwo, Jones, Kalu, Ukoha, Olagundoye, Goke, Okorie, Ikechukwu, Abiodun Idowu Okunlola, Milind, Chitnis, Helga, Nauhaus, Danelle, Erwee, Robyn, Brown, Agata, Chylinska, Robin, Simpson, Prasanna, Gomes, Marco Aurelio Ciriaco Padilha, Elvercio Pereira de Oliveira Junior, Lucas Garschagen deCarvalho, Fabiola Leonelli Diz, Mohamed El Kassas, Usama, Eldaly, Ahmed, Tawheed, Mohamed, Abdelwahab, Oudrhiri Mohammed Yassaad, Bechri, Hajar, El Ouahabi Abdessamad, Arkha, Yasser, Hessissen, Laila, Farah Sameer Yahya, Sandip Kumar Rahul, Vijayendra, Kumar, Digamber, Chaubey, Maria Teresa Peña Gallardo, Jacqueline Elizabeth Montoya Vásquez, Juan Luis García León, Sebastián Shu Yip, Georgios, Karagiannidis, Rejin, Kebudi, Sema Bay Buyukkapu, Krishna Kumar Govindarajan, Kumaravel, Sambandan, Smita, Kayal, Gunaseelan, Karunanithi, Bikash Kumar Naredi, Bibekanand, Jindal, Mariam, Lami, Matthew Hv Byrne, Duha, Jasim, Harmit, Ghattaura, Eric, W Etchill, Daniel, Rhee, Stacy, Cooper, Kevin, Crow, Morgan, Drucker, Megan, Murphy, Benjamin, Shou, Alan, Siegel, Yasin, Kara, Gül Nihal Özdemir, Mahmoud, Elfiky, Ehab El Refaee, John George Massoud, Ayah Bassam Ibrahim, Ruaa Bassam Ibrahim, Faris Abu Za'nouneh, Ranya, M Baddourah, Toqa, Fahmawee, Ayah Al Shraideh, Ghazwani, Salman, Ehab, Alameer, Al-Mudeer, Ali, Ghazwani, Yahia, Khozairi, Waleed, Ahmad, Ozair, Ankur, Bajaj, Bal Krishna Ojha, Kaushal Kishor Singh, Atique, Anwar, Vinay, Suresh, Mohamad, K Abou Chaar, Iyad, Sultan, Khalil, Ghandour, Shaima', Al-Dabaibeh, Ammar, Al-Basiti, Hazim, Ababneh, Omaima, El-Qurneh, Yousef, Alalawi, Ahmad Al Ayed, Ehab, Hanafy, Naif Al Bolowi, Anette, S Jacobsen, Heidi, Barola, Aubrey, L Pagaduan, Jingdan, Fan, Olumide Abiodun Elebute, Adesoji, O Ademuyiwa, Christopher, O Bode, Justina, O Seyi-Olajide, Oluwaseun, Ladipo-Ajayi, Felix, M Alakaloko, George, C Ihediwa, Kareem, O Musa, Edamisan, O Temiye, Olufemi, Oni, Adeseye, M Akinsete, Janita, Zarrish, Ramsha, Saleem, Soha, Zahid, Atiqa, Amirali, Ahsan, Nadeem, Sameer Saleem Tebha, Zonaira, Qayyum, Sana, Tahir, Anneqa, Tahir, Rabbey Raza Khan, Ayesha, Mehmood, Iqra, Effendi, Taimur Iftikhar Qureshi, Pooja, Kumari, Mohamed, Bonna, Khaled, Mamdouh, Mohamed, Atef, Mohamed, Faried, Victor, Calvagna, Nathalie, Galea, Ariana, Axiaq, Matthew, R Schuelke, Jake, A Kloeber, Robert, L Owen, Alexander, S Roth, Catherine, Yang, J Hudson Barnett, Lucien, P Jay, Kirk David Wyatt, Paul, J Galardy, Bernard, Mbwele, Irene, Nguma, Moshi Moshi Shabani, Amani, Twaha, Bilal, Matola, Agnes, Vojcek, Mahmoud Maher Abdelnaby Alrahawy, Seham, M Ragab, Abdallah, R Allam, Eman Ibrahim Hager, Abdelrahman, Azzam, Ammar, Ayman, Kıvılcım Karadeniz Cerit, Adnan, Dağçınar, Tümay, Umuroğlu, Ayten, Saraçoğlu, Mustafa, Sakar, Can, Kıvrak, Gül, Çakmak, Ibrahim, Sallam, Gamal, Amira, Mohamed, Sherief, Ahmed, Sherif, Simone deOliveira Coelho, Arissa, Ikeda, Licia, Portela, Marianne Monteiro Garrigo, Ricardo Vianna deCarvalho, Fernanda, Lobo, Sima Ester Ferman, FernandaFerreira daSilva Lima, Moawia Mohammed AliElhassan, Nada Osman Yousif Elhaj, Hytham Ks Hamid, Emmanuel, A Ameh, Vincent, E Nwatah, Adewumi, B Oyesakin, Andrew Nwankwo Osuigwe, Okechukwu Hyginus Ekwunife, Chisom Adaobi Nri-Ezedi, Eric Okechukwu Umeh, Nellie, Bell, Ibukunolu Olufemi Ogundele, Abiodun Folashade Adekanmbi, Olubunmi Motunrayo Fatungase, Olubunmi Obafemi Obadaini, Sarah, Al-Furais, Humaida, Hemlae, Sreylis, Nay, John, Mathew, M Jeffri Ismail, R, Simone deCamposVieira Abib, Fabianne Altruda de Moraes Costa Carlesse, Mayara Caroline Amorim Fanelli, Fernanda Kelly Marques de Souza, Pierfrancesco, Lapolla, Andrea, Mingoli, Denis, Cozzi, Anna Maria Testi, Paolo, Musiu, Paolo, Sapienza, Gioia, Brachini, Martina, Zambon, Simona, Meneghini, Pierfranco, Cicerchia, Bruno, Cirillo, Manjul, Tripathi, Sandeep, Mohindra, Vishal, Kumar, Ninad, R Patil, Richa, Jain, Renu, Madan, Madhivanan, Karthigeyan, Pravin, Salunke, Gopal, Nambi, Abdulrahman Omar Taha, Janice Hui Ling Wong, Norehan, Johari, Anas, Shikha, Win SabaiPhyu Han, Zahidah, Ahmad, Yen Yan Lim, Roserahayu, Idros, Noorainun Mohd Yusof, David Nelson Jaisingh, Aouabed, Nesrine, Bouaoud, Souad, Mebarki, Malika, Bioud, Belkacem, Fayza, Haider, Fatema Naser AlFayez, Fakher, Rahim, Elana, Kleinman, Taylor, Ibelli, Emily, Hamilton, Rochelle, Fayngor, Tzvi, Najman, Gideon, Karplus, Etai, Adam, Daniella, Melamed, Cecilia, Paasche, Amir, Labib, Farman Ali Laghari, Zainab Al Balushi, Abdulhakim Awadh SalimAl-Rawas, Ali Al Sharqi, Ammar Saif AlShabibi, Ismail Al Bulushi, Muna, Alshahri, Abdulrahman, Almirza, Ola Al Hamadani, Jawaher Al Sharqi, Anisa Al Shamsi, Bashar, Dawud, Sareya Al Sibai, Alhassan, Abdul-Mumin, Halwani Yaninga Fuseini, Peter Gyamfi Kwarteng, Abubakari Bawa Abdulai, Sheba Mary Pognaa Kunfah, Gilbert, B Bonsaana, Stephanie, Ajinkpang, Edmund, M Der, Francis, A Abantanga, Mary Joan Kpiniong, Kingsley Aseye Hattor, Kingsley Appiah Bimpong, Mohamed, Elbahnasawy, Sherief, Abdelsalam, Ahmed, Samir, Reto, M Baertschiger, Andreea, C Matei, Augusto, Zani, Lubna, Samad, Hira Khalid Zuberi, Kishwer, Nadeem, Naema, Khayyam, Fatima Ambreen Imran, Nida, Zia, Sadia, Muhammad, Muhammad Rafie Raza, Muhammad Rahil Khan, Alaa, Hamdan, Ammar, Omran, Ahmed, Moussa, Bardisan, Gawrieh, Hassan, Salloum, Alaa, Ahmed, Abdeljawad, Mazloum, Ali, Abodest, Nisreen, Ali, Munawar, Hraib, Victor, Khoury, Abdulrahman, Almjersah, Mohammad Ali Deeb, Mohammad Ahmad Almahmod Alkhalil, Akram, Ahmed, Waseem, Shater, Ali Farid Alelayan, Alaa, Guzlan, Ahmad, Bouhuwaish, Alqasim, Abdulkarim, Eman, Abdulwahed, Marwa, Biala, Reem, Ghamgh, Amani, Alamre, Marwa, Shelft, Asmaa Am Albanna, Hoda, Tawel, Emmanuel, Hatzipantelis, Athanasios, Tragiannidis, Eleni, Tsotridou, Assimina, Galli-Tsinopoulou, Dayang AnitaAbdul Aziz, Zarina Abdul Latiff, Hamidah, Alias, C-Khai, Loh, Doris, Lau, Azrina Syarizad Khutubul Zaman, Taiwo Akeem Lawal, Kelvin Ifeanyichukwu Egbuchulem, Olakayode Olaolu Ogundoyin, Isaac Dare Olulana, Biobele, J Brown, Oluwasegun Joshua Afolaranmi, Abdulbasit, Fehintola, Annika, Heuer, Christine, Nitschke, Michael, Boettcher, Matthias, Priemel, Lennart, Viezens, Martin, Stangenberg, Marc, Dreimann, Alonja, Reiter, Jasmin, Meyer, Leon, Köpke, Karl-Heinz, Frosch, Samson, Olori, Uduak, Offiong, Philip Mari Mshelbwala, Fashie Andrew Patrick, Aminu Muhammed Umar, N Otene ThankGod, Shireen Anne Nah, Yuki Julius Ng, Syukri Ahmad Zubaidi, Murad, Almasri, Sara, Ali, Rasaq, Olaosebikan, Akila, Muthukumar, Patricia, Shinondo, Amon, Ngongola, Bruce, Bvulani, Azad, Patel, Abdullahi, Nuhu-Koko, Baba, Jibrin, Ajiboye, L Olalekan, Christopher, S Lukong, Ezekiel, I Ajayi, Gabriela, Guillén, Sergio, López, José Andrés Molino, Pablo, Velasco, Omar, Elmandouh, Omar, Hamam, Rim, Elmandouh, Nensi Melissa Ruzgar, Rachel, Levinson, Shashwat, Kala, Sarah, Ullrich, Emily, Christison-Lagay, Reto, Baertschiger, Essam, Elhalaby, Muath, Alser, Mahmoud, M Saad, Luca, Pio, Guido, Seitz, Judith, Lindbert, Francis, Abantanga, Georgios, Tsoulfas, Asimina, Galli-Tsinopoulou, Nitin James Peter, Vrisha, Madhuri, Ravi, Kishore, Maryam Ghavami Adel, Virgone, Calogero, Francesco, Pata, Gaetano, Gallo, Mohammad, K Abou Chaar, Dayang Anita Abdul Aziz, Outani, Oumaima, Zineb, Bentounsi, Adesoji, Ademuyiwa, Dhruva Nath Ghosh, Lily, Saldana, Jan, Godzinsky, Abdelbasit, Ali, Dragana, Janic, Mohamed Bella Jalloh, Annette, Jacobsen, Chan Hon Chui, Israel Fernandez Pineda, Lucas, Krauel, Maricarmen, Olivos, Waha, Rahama, Hazim, Elfatih, Raphael, N Vuille-Dit-Bille, Arda, Isik, Asim Noor Rana, Kate, Cross, Andrea, Hayes-Jordan, Roshni, Dasgupta, Mohamedraed, Elshami, Collaborative, Global Health Research Group on Children’s Non-Communicable Diseases, and Bandyopadhyay S., Peter N., Lakhoo K., Abib S. d. C. V. , Abdelhafeez H., Wilson S., Pachl M., Martin B., Nagras S., Sheth M., et al.

Subjects
Social Sciences and Humanities, Health (social science), Social Sciences (SOC), Sosyal Bilimler ve Beşeri Bilimler, Epidemiology, IMPACT, SOCIAL SCIENCES, GENERAL, LOW-INCOME, Sağlık Bilimleri, paediatrics, REGISTRIES, Sociology, Occupational Therapy, Neoplasms, Epidemiyoloji, Health Sciences, ADOLESCENTS, Genel Sosyal Bilimler, Humans, cancer, Sosyal ve Beşeri Bilimler, Social Sciences & Humanities, Prospective Studies, Child, Sosyoloji, Pandemics, Halk, Çevre ve İş Sağlığı, Güvenlik Araştırması, RISK, PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH, PEDIATRIC CANCER, COVID-19, health systems, CHILDHOOD-CANCER, SARS-CoV-2, MORTALITY, Health Policy, Public Health, Environmental and Occupational Health, General Social Sciences, Sosyal Bilimler Genel, CARE, KAMU, ÇEVRE VE İŞ SAĞLIĞI, İş Sağlığı ve Terapisi, SURVIVAL, Sosyal Bilimler (SOC), Safety Research, Sağlık (sosyal bilimler)
Abstract

IntroductionChildhood cancer is a leading cause of death. It is unclear whether the COVID-19 pandemic has impacted childhood cancer mortality. In this study, we aimed to establish all-cause mortality rates for childhood cancers during the COVID-19 pandemic and determine the factors associated with mortality.MethodsProspective cohort study in 109 institutions in 41 countries. Inclusion criteria: children ResultsAll-cause mortality was 3.4% (n=71/2084) at 30-day follow-up, 5.7% (n=113/1969) at 90-day follow-up and 13.0% (n=206/1581) at 12-month follow-up. The median time from diagnosis to multidisciplinary team (MDT) plan was longest in low-income countries (7 days, IQR 3–11). Multivariable analysis revealed several factors associated with 12-month mortality, including low-income (OR 6.99 (95% CI 2.49 to 19.68); pConclusionsChildren with cancer are more likely to die within 30 days if infected with SARS-CoV-2. However, timely treatment reduced odds of death. This report provides crucial information to balance the benefits of providing anticancer therapy against the risks of SARS-CoV-2 infection in children with cancer.

Published
2022

188. Contributors

Author

Sami G. Al-Ghamdi, Ibtisam Sulaiman Alhosni, Omar Amoudi, Fenna Blomsma, Geraldine Brennan, Anton Brummelhuis, Nicola Callaghan, Joana Costa, Marco Cucchi, Dimo Dimov, Azadeh Dindarian, Karine Van Doorsselaer, Hilde Engels, K.I. Evangelinos, M.A. Fernández López, Anna Maria Ferrari, Karen Fortuin, Robin Foster, G. Fountoulakis, Tânia Freitas, Victor Fukumoto, Fernando E. García-Muiña, Darya Gerasimenko, Helena I. Gomes, João Pedro Moreira Gonçalves, Emma Goosey, Rafael Hernández López, Alistair Ho, Holger Hoppe, Beijia Huang, M. Hughes, Susan L. Hull, R. Husgafvel, Konstantinos Iatridis, Jan Jonker, René Kemp, A. Kipritsis, Nermin Kişi, G. Lanaras-Mamounis, L. Linkosalmi, Cembalo Luigi, Warren E. Mabee, Monica Mihaela Maer-Matei, Sergey Makaryan, Mehzabeen Mannan, Thomas Marinelli, Borrello Massimiliano, Deepak John Mathew, William M. Mayes, Erica Mazerolle-Castillo, M. Sonia Medina-Salgado, O. Mikroni, Eva Militaru, Alberto Fernandez Minguela, Irina Mkrtchyan, Cristina Mocanu, Ioannis E. Nikolaou, Piotr Nowakowski, Satoshi Ohnishi, Juyeon Park, Seigo Robinson, Indranil Saha, D. Sakaguchi, Daniel Rolph Schneider, Anastasios Sepetis, Davide Settembre-Blundo, Manuela Castro Silva, Keith R. Skene, Alexandros I. Stefanakis, Krzysztof Szwarc, Mike Tennant, Tihomir Tomić, Thomas A. Tsalis, Alisha Tuladhar, Serdar Türkeli, Elena Turrado Domínguez, Alexandre Meira de Vasconcelos, Konstantinos I. Vatalis, P. Vouros, Mariusz Wala, K.S. Winans, and Ana Maria Zamfir

Published
2022

191. New age zero waste sustainable apparel industry: Design practices, innovative approaches, and technological intervention

Author

Indranil Saha and Deepak John Mathew

Subjects
Intervention (law), Textile industry, business.industry, Circular economy, Sustainability, Zero waste, Production (economics), Business, Manufacturing methods, Clothing, Industrial organization
Abstract

This chapter presents contemporary design practices in the apparel industry, which are in line with the concept of the circular economy. It begins with an explanation of the distinctive features and ecological challenges of the apparel industry. The chapter then explains the association between sustainability and the apparel industry by exploring various domains, including design, production, and consumption practices. A comprehensive discussion of ethical and consumption-based concerns is also included in determining their connection with the main elements of the circular economy in the apparel industry. It ends with the explanation of the core components of the zero waste apparel design and manufacturing methods, including historical evidence, creative pattern making techniques, various methods of textile production, and technological innovations.

Published
2022

196. Presentation and outcome of traumatic spinal fractures

Author

Ahmed El-Faramawy, Ayman El-Menyar, Ahmad Zarour, Kimball Maull, Jane Riebe, Krishna Kumar, John Mathew, Ashok Parchani, Hassan Al-Thani, and Rifat Latifi

Subjects
Cord injury, fracture, spine, trauma, Qatar, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

Background: Motor vehicle crashes and falls account for most of the spine fractures with subsequent serious disability. Aim: To define the incidence, causes, and outcome of spinal fractures. Materials and Methods: Data were collected retrospectively from trauma registry database of all traumatic spinal injuries admitted to the section of trauma surgery in Qatar from November 2007 to December 2009. Results: Among 3712 patients who were admitted to the section of trauma surgery, 442 (12%) injured patients had spinal fractures with a mean age of 33.2 ± 12 years. The male to female ratio was 11.6:1. Motor vehicle crashes (36.5%) and falls from height (19.3%) were the leading causes of cervical injury (P = 0.001). The injury severity score ranged between 4 and 75. Nineteen percent of cases with cervical injury had thoracic injury as well (P = 0.04). Lumber injury was associated with thoracic injury in 27% of cases (P < 0.001). Combined thoracic and lumber injuries were associated with cervical injury in 33% of cases (P < 0.001). The total percent of injuries associated with neurological deficit was 5.4%. Fifty-three cases were managed surgically for spine fractures; 14 of them had associated neurological deficits. Overall mortalityrate was 5%. Conclusions: Spine fractures are not uncommon in Qatar. Cervical and thoracic spine injuries carry the highest incidence of associated neurological deficit and injuries at other spinal levels. Young males are the most exposed population that deserves more emphasis on injury prevention programs in the working sites and in enforcement of traffic laws.

Published
2012
Full Text
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197. Wrestle while you learn: EMG as a teaching tool for undergraduate skeletal muscle physiology teaching

Author

Vinay Oommen, Mahatabb Nundy, Anandit John Mathew, and Niranjini Chandrashekaran

Subjects
Reflex, Stretch, medicine.medical_specialty, Universities, Electromyography, Physiology, business.industry, Teaching, MEDLINE, Skeletal muscle, General Medicine, Education, Physical medicine and rehabilitation, medicine.anatomical_structure, Teaching tool, Accelerometry, medicine, Reflex, Humans, Muscle, Skeletal, business, Muscle Contraction
Published
2019

198. Nonclassical states of light in a nonlinear Michelson interferometer

Author

Bijoy John Mathew and Anil Shaji

Subjects
Quantum Physics, FOS: Physical sciences, Quantum Physics (quant-ph)
Abstract

Nonlinear quantum metrology schemes can lead to faster than Heisenberg limited scalings for the measurement uncertainty. We study a Michelson interferometer embedded in a Kerr medium [Luis and Rivas, Phys. Rev. A 92, 022104 (2015)] that leads to non-linear, intensity dependent phase shifts corresponding to relative changes in the lengths of its two arms. The quantum Cramer-Rao bound on the minimum achievable measurement uncertainties is worked out and the requirements, in practice, to saturate the bound are investigated. The choice of input state of light into the interferometer and the read out strategy at the output end are discussed. The ideal, non-classical states of light that must be used to saturate the bound are found to be highly susceptible to photon loss noise. We identify optimal states at each noise level that are both resilient to noise and capable of giving the enhanced sensitivities and discuss practical implementations of the interferometry scheme using such states., This is the published version. This paper has 9 pages and 5 figures

Published
2021

199. Automated Cobb Angle Measurement for Adolescent Idiopathic Scoliosis Using Convolutional Neural Network

Author

Wahyu Caesarendra, Wahyu Rahmaniar, John Mathew, and Ady Thien

Subjects
musculoskeletal diseases, Clinical Biochemistry, convolutional neural network (CNN), deep learning, scoliosis, spine classification, vertebrae, musculoskeletal system
Abstract

The Cobb angle measurement of the scoliotic spine is prone to inter- and intra-observer variations in the clinical setting. This paper proposes a deep learning architecture for detecting spine vertebrae from X-ray images to evaluate the Cobb angle automatically. The public AASCE MICCAI 2019 anterior-posterior X-ray image dataset and local images were used to train and test the proposed convolutional neural network architecture. Sixty-eight landmark features of the spine were detected from the input image to obtain seventeen vertebrae on the spine. The vertebrae locations obtained were processed to automatically measure the Cobb angle. The proposed method can measure the Cobb angle with accuracies up to 93.6% and has excellent reliability compared to clinicians’ measurement (intraclass correlation coefficient > 0.95). The proposed deep learning architecture may be used as a tool to augment Cobb angle measurement in X-ray images of patients with adolescent idiopathic scoliosis in a real-world clinical setting.

Published
2021

200. Immediate Reconstruction of the Nipple-areola Complex Using Inferior Pedicle Skin for Central Tumors of the Breast

Author

John Mathew

Subjects
Surgery
Abstract

The nipple-areola complex (NAC) must be considered as an integral part of the breast with regard to morale and self-assurance. Achieving good aesthetic outcome is a challenge after excision of the NAC in retroareolar tumors. This article looks into immediate reconstruction of the NAC using inferior pedicle skin in patients after central excision of retroareolar tumors. Sixteen patients had breast conservation surgery for retroareolar tumors by a single surgeon between September 2016 and November 2021, and six of them had nipple-areola reconstruction with inferior pedicle skin. None of the patients having NAC reconstruction had any recorded complications and none needed reexcision of the margins. Five out of six patients undergoing NAC reconstruction had good to excellent aesthetic outcome as recorded in the patient questionnaire. There was no locoregional recurrence or distant metastasis in the whole group after a median follow-up of 17 months (2-62).

Published
2021

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