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AMSTERDAM - Adatimumab significantly improved the painful inflammatory nodules and abscesses of hidradenitis suppurativa while maintaining a side-effect profile comparable to that of placebo in the phase III PIONEER H [...]

FROM THE EADV CONGRESS No clinically meaningful changes in laboratory values occurred in adolescents during 52 weeks on dupilumab for atopic dermatitis in a large, open-label safety study, Michael J. [...]

FROM THE EADV CONGRESS About 70% of patients on the oral selective Janus kinase 1 inhibitor abrocitinib for moderate to severe atopic dermatitis (AD) achieved high-efficacy responses without need for [...]

FROM THE EADV CONGRESS European dermatologists shifted en masse to teledermatology during the first wave of the COVID-19 pandemic, and most of them disliked the videoconferencing experience intensely, according to [...]

GUSACITINIB, A NOVEL oral inhibitor of multiple inflammatory pathways, achieved rapid and clinically meaningful improvement in corticosteroid-refractory moderate to severe chronic hand eczema in a phase 2b, randomized trial, Howard [...]

FROM ECNP 2020 There's a reason they're called smartphones. Indeed, how patients use their smartphones and where they take them provides insight into what has been termed their 'digital phenotype.' [...]

General anesthesia for ECT gets short shrift in the psychiatric literature, yet it's an indispensable part of the procedure, with a major impact on its safety and outcomes, Alexander Sartorius, [...]

EXPERT ANALYSIS FROM SOEF HAWAII DERMATOLOGY SEMINAR WAILEA, HAWAII -- The Food and Drug Administration's approval of adapalene gel 0.1% as an over-the-counter treatment for acne is a potential game [...]

A novel formulation of botulinum toxin type A substantially improved the appearance of dynamic forehead lines while garnering favorable patient satisfaction scores in an interim analysis of a phase 2 [...]

YOUNG MEN WITH HIDRADENITIS suppurativa are 'surprisingly' at increased risk for hypothyroidism, Anna Figueiredo, MD, declared at the virtual annual meeting of the American Academy of Dermatology. The surprise about [...]

FROM ECNP 2020 Objective neuropsychological tests can be used to subclassify the cognitive symptoms present in patients with major depression into three patterns having implications for treatment responsiveness, Gitte Moos [...]

LIUBLJANA, SLOVENIA -- Fever of unknown origin and pneumonia are two clinical features useful in distinguishing between influenza and respiratory syncytial virus infection as the cause of hospitalization in infants [...]

LAHAINA, HAWAII -- Clascoterone cream, a first-in-class topical selective androgen receptor inhibitor for the treatment of acne now under review by the Food and Drug Administration, is already generating considerable [...]

THE NATIONAL incidence of vulvar melanoma is on the rise in women aged over 60 years, climbing by an average of 2.2% per year during 2000-2016, Maia K. Erickson reported [...]

FROM AAS 2020 A 'GROWING AND DISTURBING' INCREASE in suicidal behavior among black youth has quietly been underway in the United States during the past several decades, even while rates [...]

ABROCITINIB, a once-daily oral Janus kinase-l(JAK-l)--selective inhibitor, achieved all key endpoints in adolescents and adults with moderate to severe atopic dermatitis in the pivotal phase 3 JADE-MONO-2 clinical trial, Melinda [...]

A 'growing and disturbing' increase in suicidal behavior among black youth has quietly been underway in the United States during the past several decades, even while rates in white and [...]

MADRID--A parental history of asthma or allergic rhinitis significantly increases the risk that a child will develop atopic dermatitis, and that risk doubles if a parent has a history of [...]

LAHAINA, HAWAII -- Clascoterone cream, a first-in-class topical selective androgen receptor inhibitor for the treatment of acne now under review by the Food and Drug Administration, is generating considerable buzz [...]

MAUI, HAWAII -- Belimumab shows promise as a novel biologic treatment for skin involvement in early diffuse cutaneous systemic sclerosis, Janet E. Pope, MD, said at the 2020 Rheumatology Winter [...]

MAUI, HAWAII -- Anti-Ro52 autoantibodies are the latest and most potent of the autoantibody predictors of interstitial lung disease (ILD) discovered in patients with juvenile dermatomyositis, Anne M. Stevens, MD, [...]

CONSIDER NUCLEOSIDE reverse transcriptase inhibitors (NRTIs) prescribed for HIV infection as a possible cause of neutrophilic eccrine hidradenitis (NEH) arising in an affected patient, Jessica Kalen, MD, advised during a [...]

If the shoe fits a presumptive clinical diagnosis of calciphylaxis, wear it--and don't assume that ordering imaging studies or histology will make for a better fit or is even necessary. [...]

LAHAINA, HAWAII -- Novel topical medications are in the works that will address the longstanding unmet need for a Food and Drug Administration-approved noncorticosteroid topical for use in pediatric atopic [...]

LAHAINA, HAWAII--Reassuring evidence of the safety of oral propranolol for treatment of complicated infantile hemangiomas in patients with PHACE syndrome comes from a recent multicenter study. Oral propranolol is now [...]

LAHAINA, HAWAII -- The rash commonly called perioral dermatitis is more appropriately termed periorificial dermatitis, according to Jessica Sprague, MD, a pediatric dermatologist at the University of California, San Diego, [...]

LAHAINA, HAWAII -- Most patients on dupilumab for the treatment of severe atopic dermatitis are best off on continuous long-term dosing of the selective Th2 cytokine inhibitor rather than treatment [...]

LAHAINA, HAWAII--General dermatologists can have a high degree of confidence in treating patients with stage I mycosis fungoides without bringing in a medical oncologist, Trilokraj Tejasvi, MBBS, said at the [...]

SPIRONOLACTONE for the treatment of endocrine therapy-induced alopecia in breast cancer survivors was not associated with increased risk of recurrence of the malignancy in a large retrospective study Chapman Wei [...]

LAHAINA, HAWAII -- The rash commonly called perioral dermatitis is more appropriately termed periorificial dermatitis, according to Jessica Sprague, MD, a pediatric dermatologist at the University of California, San Diego, [...]

LAHAINA, HAWAII--Novel topical medications are in the works that will address the longstanding unmet need for a Food and Drug Administration-approved noncorticosteroid topical for use in pediatric atopic dermatitis, Lawrence [...]

Noninvasive ventilation with helmet continuous positive air pressure (CPAP) deserves to be embraced as an effective strategy in preventing self-induced lung injury, often a key factor in progression from the [...]

LAHAINA, HAWAII -- Two recent large, well-conducted, and persuasive studies provide much-needed clarity regarding the neurodevelopmental risks posed by general anesthesia in early childhood, Jessica Sprague, MD, said at the [...]

MAUI, HAWAII -- The 15% rule in scleroderma is a handy tool that raises awareness of the disease's associated prevalence of various severe organ complications so clinicians can screen appropriately, [...]

A powerful genetic predisposition to cardiovascular disease was overcome by low lifetime exposure to LDL cholesterol and systolic blood pressure in a naturalistic study conducted in nearly half a million [...]

MADRID -- Adults with atopic dermatitis (AD) face significantly increased risks of osteoporosis and major osteoporotic fractures--even if they've never taken systemic corticosteroids, according to a large observational Danish national [...]

MADRID -- Dermatologic clinical trialist Kim A. Papp, MD, PhD, is known to pick his words carefully, and the word he uses to describe the quality of life improvement documented [...]

MADRID -- Soft-tissue ultrasound is helpful in determining whether fistulae in patients with hidradenitis suppurativa (HS) will respond to medical therapy or require surgical excision, Antonio Martorell, MD, said at [...]

MADRID -- A parental history of asthma or allergic rhinitis significantly increases the risk that a child will develop atopic dermatitis (AD), and that risk doubles if a parent has [...]

PHILADELPHIA -- Engaging in at least 150 minutes of moderate to vigorous physical activity per week as recommended in national guidelines appears to mitigate the cardiometabolic risks associated with poor [...]

MADRID -- Adding the oral Janus kinase (JAK) inhibitor baricitinib to standard atopic dermatitis (AD) therapy with low- and midpotency topical corticosteroids markedly improved disease severity and key patient-reported outcomes, [...]

MADRID -- Oral apremilast's beneficial effects on Behcet's disease oral ulcer disease severity and patient quality of life were sustained through week 64 of the long-term extension phase of the [...]

MADRID -- The risk of serious adverse events in patients on certolizumab varies considerably across indications for use of the biologic, with differential disease-related rates of systemic corticosteroid use and [...]

COPENHAGEN -- Paying patients with schizophrenia a modest sum to take their long-acting injectable antipsychotic agents is a proven, evidence-based strategy for achieving improved adherence. Now it's time to find [...]

COPENHAGEN -- The traditional treatment paradigm for patients with comorbid depression and insomnia has been to focus on the depression in expectation that the sleep problems will fade away with [...]

SAN ANTONIO - Oral supplementation with a proprietary blend of human milk oligosaccharides improved all of the core symptoms of irritable bowel syndrome in a large open-label study, Magnus Simren, [...]

MADRID - European atopic dermatitis experts have issued formal guidance on a seriously neglected topic: treatment of the disease during pregnancy, during breastfeeding, and in men planning to father children. [...]

MADRID -- Nemolizumab, an investigational humanized monoclonal antibody targeting the interleukin-31 receptor alpha subunit, achieved rapid and clinically meaningful improvement in both itch and skin lesions of severe prurigo nodularis [...]

MADRID -- In a phase 2, dose-ranging study, 78% of patients with long-standing moderate or severe alopecia areata rated their condition as 'much improved' or 'very much improved' after 24 [...]

MADRID -- Repigmentation in patients with vitiligo documented at 24 weeks continued to increase up to 1 year, in a randomized clinical trial of ruxolitinib cream for the treatment of [...]