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705 results on '"Iughetti L."'

154. Storia naturale della tiroidine di Hashimoto eutiroidea

Author

Radetti, G., Gottardi, E., Bona, G., Buzi, F., Caimmi, S., Larizza, D., Cappa, M., Corrias, A., Gastaldi, R., Greggio, N., Iughetti, L., Lauriola, S., Loche, S., Mastrangelo, C., Salardi, S., Salerno, M., Salvatoni, A., Sposito, M., Tonini, G., Vigoni, Mc, Volta, C., and Wasniewska, Malgorzata Gabriela

Published
2005

155. Diabetes incidence in 0- to 14-year age-group in Italy: a 10-year prospective study

Author

Carle, Flavia, Gesuita, Rosaria, Bruno, Graziella, Coppa, Giovanni V, Falorni, Alberto, Lorini, Renata, Martinucci, Marco E, Pozzilli, Paolo, Prisco, Francesco, Songini, Marco, Tenconi, Maria T, Cherubini, Valentino, RIDI Study Group (Piffer, S, Franchini, S, Bianchi, L, Cerutti, F, Merletti, F, Pagano, G, Cotellessa, M, Minicucci, L, Barbieri, P, Devoti, G, D’Annunzio, G, Bazzano, S, Toni, S, Reali, Ms, Medici, A, Iughetti, L, Predieri, B, Balli, F, Visalli, N, Sebastiani, L, Marietti, G, Santeusanio, F, De Giorgi, G, Santilli, E, Iannilli, A, Pinelli, A, Mascioli, G, Altobelli, E, Chiarelli, F, Tumini, S, Iafusco, D, De Felice, E, Ingenito, N, Casu, A, Frongia, P, and Marinaro, A)

Subjects
Male, Adolescent, Child, Child, Preschool, Demography, Diabetes Mellitus, Type 1, Female, Humans, Incidence, Infant, Italy, Registries, Sex Characteristics, Diabetes Mellitus, Preschool, Type 1
Abstract

The Registry for Type 1 Diabetes Mellitus in Italy (RIDI) Study Group was established to coordinate the registries of type 1 diabetes in Italy. This report is based on 3,606 children younger than 15 years diagnosed with type 1 diabetes and prospectively registered during 1990-1999 by nine centers, covering35% of the Italian population.Registries were pooled in four geographic macro-areas: north, central, south, and insular. The completeness of registration was assessed by the capture-recapture method. Poisson regression analysis was used to evaluate temporal trend in incidence.Large variations in incidence were confirmed not only between Sardegna and the mainland but also among peninsular areas. In Sardegna, there was an excess of boys (the boy-to-girl incidence ratio was 1.4). The overall incidence showed average increases of 3.6% (P0.001) and 3.7% (P0.001) per year in peninsular Italy and in Sardegna, respectively. Significant increases in incidence rates were found in boys aged 10-14 years (6.7%, 95% CI 0.5-13.3) and in girls aged 5-9 years (6.6%, 0.5-13.1) living in the southern area. The incidence rate also increased in boys aged 10-14 years (5.0%, 0.3-10) and in girls aged 0-4 years (4.9%, 0.8-9.1) living in Sardegna.Italy is a country with large geographical variations in incidence rates of type 1 diabetes. However, the rates are evenly increasing both in the mainland and Sardegna, suggesting that similar environmental factors are operating over populations that have different genetic backgrounds.

Published
2004

156. Death in People with Prader-Willi Sindrome: a National Survey

Author

Grugni, G., Corria, A., Bellone, J., Bosio, L., Cerioni, V., Delvecchio, M., Detoni, T., Dibattista, E., Gargantini, L., Iughetti, L., Livieri, C., Naselli, A., Pilotta, A., Pozzan, G., Ragusa, L., Sacco, M., Salvatoni, Alessandro, Sanzari, A., Sartorio, A., Trifir, G., Aimaretti, G., and Crin, A.

Published
2004

158. Growth hormone treatment of adolescents with growth hormone deficiency (GHD) during the transition period: results of a survey among adult and paediatric endocrinologists from Italy. Endorsed by SIEDP/ISPED, AME, SIE, SIMA

Author

Aimaretti, G., primary, Attanasio, R., additional, Cannavò, S., additional, Nicoletti, M. C., additional, Castello, R., additional, Di Somma, C., additional, Garofalo, P., additional, Iughetti, L., additional, Loche, S., additional, Maghnie, M., additional, Mazzanti, L., additional, Saggese, G., additional, Salerno, M., additional, Tonini, G., additional, Toscano, V., additional, Zucchini, S., additional, and Cappa, M., additional

Published
2014
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160. Diagnostic approach and therapy of overgrowth and tall stature in childhood

Author

Iughetti, L., Bergomi, A., and Bernasconi, S.

Subjects
Male, therapy, diagnosis, Humans, Growth disorders, Female, Child, Child development, Growth disorders, diagnosis, Growth disorders, therapy, Gigantism
Abstract

Although referral for evaluation of tall stature is much less common than for short stature, early diagnosis in the paediatric age of clinical pictures leading to tall stature is crucial, both in order to detect conditions which can be properly treated and in order to limit excessive final heights; nowadays tall stature may be cause of psychosocial problems. This paper reviews different items related to tall stature in childhood. First of all, our review focuses on the definition of tall stature and the classification of the main clinical conditions associated with either tallness or excessive growth is discussed. Secondly, the clinical picture and the most recent breakthroughs of each of these conditions are reviewed. A diagnostic flow-chart meant to approach a patient presenting with tall stature is designed according to a few simple parameters such as chronological age, height age, bone age and growth velocity. The novel advances in the understanding of constitutional and secondary tall stature are presented and discussed, together with the hormonal treatment of constitutional tall stature and other related outstanding questions.

Published
2003

161. [Treatment of childhood obesity]

Author

Trifirò, G, Salvatoni, A, Tanas, R, Brambilla, P, Maffeis, Claudio, Cammareri, V, Corciulo, N, Mulè, Rm, Peverelli, P, Cerutti, F, Rabbone, I, Saggese, G, Miniero, R, Bernasconi, S, Chiumello, G, Rondanini, Gf, Manzoni, P, Ambruzzi, Am, Morino, G, Cuccarolo, G, Del Majno UM, Monetti, N, Martino, R, Grugni, G, Crinò, A, Ciampalini, P, Beccaria, L, Caselli, G, Balsamo, A, Cicognani, A, Greggio, Na, Modestini, E, Iughetti, L, Predieri, B, De Sanctis, V, Franzese, A, Yannakou, P, Guerraggio, L, Luciano, A, Livieri, C, Di Pietro ME, Bergamaschi, G, Valerio, G, and Grezzani, A.

Subjects
Adult, Counseling, Male, Adolescent, physical activity, Body Mass Index, Sex Factors, children, Dexfenfluramine, Behavior Therapy, Pregnancy, Appetite Depressants, Humans, Family, Obesity, Child, Exercise, Life Style, therapy, Motivation, Human Growth Hormone, Puberty, Age Factors, obesity, diet, Diet, Serotonin Receptor Agonists, Pregnancy Complications, Child, Preschool, Female, Energy Intake
Abstract

This article provides current guidelines on the treatment and prevention of childhood obesity. Since factors involved in obesity change with age, the therapeutic approach in pre-school children will be different from pupils and adolescents. The treatment will also be modulated on the basis of weight excess, weight gain velocity and complications. The main goal of the treatment should be to encourage the child and his family to have healthy lifestyle. Families who are not ready for change might benefit from counselling to improve motivation before starting treatment. A detailed alimentary and behavioural history is the start point of the treatment. The strategy of the intervention is to induce changes at three levels: 1) attitudes of parents; 2) physical activity; 3) energy intake. The treatment of the adolescents should take into account the pubertal changes and the psychological aspects of this peculiar period of life. Obesity is a chronic disease and its treatment needs long-life follow-up. The long-term results of the obesity treatment are often disappointing and we have to consider consistent prevention programs for better results.

Published
2003

162. Diabete Mellito

Author

Chiumello, G, Cerruti, F, Chiarelli, F, Dammacco, F, Iughetti, L, Lorini, RENATA GIUSEPPINA, Meschi, F, Pinelli, L, and Vanelli, M.

Published
2003

164. RISK FOR THE DEVELOPMENT OF TYPE I DIABETES IN CHILDREN WITH INCIDENTAL HYPERGLYCEMIA (MULTICENTER ITALIAN STUDY) DIABETES CARE

Author

Lorini, L., Alibrandi, A., Vitali, L., Martinetti, M., Betterle, C., D'Annunzio, G., Cherubini, E. BONIFACIO AND PEDIATRIC ITALIAN STUDY GROUP OF PREDIABETES V., Cavallo, L., Dammacco, F., Cerasoli, G., Pocecco, M., Tumini, S., Chiarelli, F., Mancuso, M., Banin, P., Toni, S., Martinucci, M., Barella, C., Coltellessa, M., Monaci, A., Lombardo, F., Meschi, F., Chiumello, G., Iughetti, L., Brnasconi, S., Iafusco, D., Prisco, F., Franzese, A., Cadario, F., Cardella, F., Monciotti, C., Giacchero, R., Avanzini, M. A., Calisti, M. A. L., Chiari, G., Vanelli, M., Guazzarotti, L., Sulli, Nicoletta, Multari, G., Crin, A., Marietti, G., Piccinini, S., MANCA BITTI, L. M., Sacchini, P., Masciani, A., Sacchetti, C., Cerutti, F., Tonini, G., Visentin, A., Contreas, G., and Pinelli, L.

Published
2001

166. Obesità

Author

Iughetti, L, Beccaria, L, Brambilla, P, De Simone, M, Maffeis, Claudio, Salvatoni, A, and Seminara, S.

Published
2001

167. Genetics and molecular biology of the GHRH-GH-IGF-I axis

Author

Bernasconi S, Bergomi A, Milioli S, Tirendi A, Mastronardi G, Mariani S, Barbara PREDIERI, Ferrari M, Geti M, Livio L, Rossi K, Forese S, and Iughetti L

Subjects
Adult, Male, Human Growth Hormone, Gene Expression, Humans, Point Mutation, Dwarfism, Female, Insulin-Like Growth Factor I, Growth Hormone-Releasing Hormone
Abstract

In this paper, the genetics and molecular biology of the GHRH-GH-IGF-I (Growth Hormone Releasing hormone-Growth Hormone-Insulin like Growth Factor I) axis involved in the pathogenesis of short stature are reviewed. Short stature associated with GH deficiency is estimated to occur in about 1/4000-10,000 live births; 3-30% of cases affect first-degree relatives, suggesting a genetic aetiology. Identification of such molecular defects is very recent and dependent on new findings on the physiology of GHRH-GH-IGF-I axis: for example the pituitary-specific transcription factors and their mutations have only been described in the last few years. The epidemiological importance of the identified molecular defect depends on the level of the axis involved, but the prevalence of some of these genetic defects is probably underestimated. Time will tell what the practical relevance of these findings is and what the clinical features of the new mutations are; we will probably learn something more about the GHRH-GH-IGF-I axis: to date, no mutations have been reported regarding the GHRH gene or the IGF-I receptor.

Published
2000

171. La sindrome di Prader-Willi

Author

Beccaria, L, Bosio, L., Benzi, F., Bregani, P., Achutegui, I., Chiumello, G., Livieiri, C., Trifir, G., DE TONI, T., Iughetti, L., Ragusa, L., Salvatoni, Alessandro, Tonini, G., Corrias, A., and Crino, A.

Published
1999

172. L'obesità in età evolutiva: stato dell'arte

Author

Pinelli, Leonardo, Pietrobelli, Angelo, Catassi, G., Balsamo, A., Seminara, S., De Toni, T., De Simone, M., Beccaria, L., Chiumello, G., Trifirò, G., Bernasconi, S., Iughetti, L., Franzese, A., Livieri, C., Ambruzzi, A. M., Crinò, A., Meneghetti, E., Morino, G., and Yannakou, P.

Published
1999

173. Standard di assistenza per la prevenzione e cura dell'obesità infantile

Author

Brambilla, P., Catassi, C., DE SIMONE, M., Cavallo, L., Damacco, F., Peverelli, P., Cacciari, E., Balsamo, A., Cicchetti, M., Reitano, G., LO PRESTI, D., Bergamaschi, G., Seminara, S., Grifi, G., Caroli, M., Corciulo, N., DE TONI, T., DI PIETRO, M., GOBIO CASALI, L., DE LUCA, F., Chiumello, G., Beccaria, L., Cammareri, V., Trifir, G., Berbasconi, S., Iughetti, L., Franzese, A., Vido, L., Antonello, I., Greggio, N., Agnello, D., Mul, R. M., Livieri, C., Saggese, G., Barsanti, S., Sposito, M., Bartolotta, E., Crin, A., Ambruzzi, A., Morino, G., Menghetti, E., Yiannakou, P., Falorni, A., DE GIORGI, G., Corrias, A., Cerutti, F., Rabbone, I., Fontana, F., Uasone, R., Guerraggio, L., Tonini, G., Valerio, G., Salvatoni, Alessandro, Cuccarolo, G., Monetti, N., Maffeis, C., Tat, L., Luciano, A., and Pinelli, L.

Published
1999

174. Metabolic syndrome in adult patients with Prader–Willi syndrome

Author

Grugni, G., primary, Crinò, A., additional, Bedogni, G., additional, Cappa, M., additional, Sartorio, A., additional, Corrias, A., additional, Di Candia, S., additional, Gargantini, L., additional, Iughetti, L., additional, Pagano, C., additional, Ragusa, L., additional, Salvatoni, A., additional, Spera, S., additional, Vettor, R., additional, Chiumello, G., additional, and Brambilla, P., additional

Published
2013
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176. POI: A Score to Modulate GH Treatment in Children with Prader-Willi Syndrome

Author

Salvatoni, A., primary, Berini, J., additional, Chiumello, G., additional, Crinò, A., additional, Di Candia, S., additional, Gargantini, L., additional, Grugni, G., additional, Iughetti, L., additional, Luce, A., additional, Musolino, G., additional, Sogno Valin, P., additional, Spica Russotto, V., additional, and Trifirò, G., additional

Published
2012
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177. [Non-specific pituitary responses in insulin-dependent diabetes mellitus in children and adolescents]

Author

Iughetti, L., Petraglia, F., Facchinetti, F., Genazzani, A. R., Cozzini, A., Vanelli, M., and Bernasconi, S.

Subjects
Adult, Male, Adolescent, Pituitary Function Tests, beta-Endorphin, Thyrotropin, Luteinizing Hormone, pituitary, Gonadotropin-Releasing Hormone, Diabetes Mellitus, Type 1, Reference Values, Growth Hormone, diabetes mellitus, Humans, Female, Follicle Stimulating Hormone, Child, Thyrotropin-Releasing Hormone
Abstract

Several reports indicate a number of changes in the control of the release of PRL, LH, FSH, GH and beta-endorphin (B-EP) as a result of insulin-dependent diabetes mellitus (IDDM). In this study we evaluate the presence of non-specific pituitary responses to releasing hormones in IDDM children and adolescents.The non-specific effects of TRH on plasma GH, LH and B-EP levels and of GnRH on plasma GH, PRL, TSH and B-EP levels were measured in 16 IDDM children and in 16 healthy children matched by age and sex. All subjects were tested with injection of TRH (200 micrograms i.v. bolus) and GnRH (50 micrograms i.v. bolus). GH, TSH, PRL, LH and B-EP levels were evaluated with radioimmunological methods on blood samples collected before and after stimulation by releasing hormones.GH and B-EP non-specific responses to TRH and GnRH were significantly more pronounced in IDDM patients than in controls. All patients showed at least one non-specific response to one of the two releasing hormones. No significant correlations were found between non-specific pituitary responses and the patient's age, the duration and onset of disease or the degree of metabolic control.These observations may indicate that: in IDDM hypothalamus-pituitary regulating mechanism is altered; the hormones whose levels are most often found to be abnormal in IDDM (other than insulin) are also hormones which respond non specifically to the neuropeptides TRH and GnRH.

Published
1995

178. Insulin resistance is a risk factor for high blood pressure regardless of body size and fat distribution in obese children

Author

Maffeis, C., primary, Banzato, C., additional, Brambilla, P., additional, Cerutti, F., additional, Corciulo, N., additional, Cuccarolo, G., additional, Di Pietro, M., additional, Franzese, A., additional, Gennari, M., additional, Balsamo, A., additional, Grugni, G., additional, Iughetti, L., additional, Del Giudice, E. Miraglia, additional, Petri, A., additional, Trada, M., additional, and Yiannakou, P., additional

Published
2010
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182. A Survey on Prader-Willi Syndrome in the Italian Population: Prevalence of Historical and Clinical Signs

Author

Crinò, A., primary, Di Giorgio, G., additional, Livieri, C., additional, Grugni, G., additional, Beccaria, L., additional, Bosio, L., additional, Corrias, A., additional, Chiumello, G., additional, Trifirò,, G., additional, Salvatoni, A., additional, Tonini, G., additional, Gargantini, L., additional, de Toni, T., additional, Valerio, G., additional, Ragusa, L., additional, Franzese, A., additional, Rinaldi, M.M., additional, Spera, S., additional, Castelli Gattinara, G., additional, Villani, S., additional, Iughetti, L., additional, and (ISPED), Genetic Obesity Study Group of the, additional

Published
2009
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184. Obesità essenziale Proposta di cartella clinica in età pediatrica

Author

Cerutti, M., De Simone, M., Monetti, N., Corrias, A., Rusconi, R., Gastaldi, R., Salvatoni, Alessandro, Vido, L., Maffeis, C., Peverelli, P., Crinò, A., Tonini, G., Degiorgi, G., Iughetti, L., Grassi, R., Balsamo, A., Livieri, C., Gobio Casali, L., Brambilla, P., Uasone, R., Cuccarolo, G., De Toni, T., Riganti, G., Antonello, I., Pinelli, L., Sposito, M., Bernasconi, S., Bellizzi, M., Lorini, R., Fontana, F., and Chiumello, G.

Published
1992

186. La sindrome di Prader-Willi-Labart

Author

Tonini, G., Crinò, A., Livieri, C., Brambilla, P., Vido, L., Pinelli, L., Corrias, A., De Simone, M., Balsamo, A., Sposito, M., De Toni, T., Balestrazzi, P., Salvatoni, Alessandro, Cerutti, F., Borrelli, P., Lorini, R., Pozzan, G. B., Maffeis, C., Gastaldi, R., Iughetti, L., Riganti, G., Seminara, S., and Chiumello, G.

Published
1991

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