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573 results on '"Hunold, P."'

170. Randomized trials in emergency medicine journals, 2008 to 2011.

Author

Jones CW, Hunold KM, Isaacs CG, Platts-Mills TF, Jones, Christopher W, Hunold, Katherine M, Isaacs, Cameron G, and Platts-Mills, Timothy F

Abstract

Study Objective: Knowledge of current areas of activity in emergency medicine research may improve collaboration among investigators and may help inform decisions about future research priorities. Randomized, controlled trials are a key component of research activity and an essential tool for improving care. We investigated the characteristics of randomized trials recently published in emergency medicine journals.Methods: This was a retrospective analysis of randomized trials published in the 5 highest impact emergency medicine journals. PubMed was searched for reports of randomized trials involving human subjects indexed to MEDLINE between January 1, 2008, and December 31, 2011. Included trials were classified with respect to study topic, funding source, presence of age-related inclusion criteria, and country of origin.Results: A total of 163 published studies were included for analysis. Pain management was the most commonly studied topic (n = 28, or 17%) followed by orthopedics (n = 24, or 15%), cardiovascular disease (n = 13, or 8%), and prehospital medicine (n = 13, or 8%). Less than half of studies received extramural funding support. Children were specifically examined in 22 (13%) of trials; only 5 trials (3%) specifically examined patients aged 60 or older.Conclusions: Emergency medicine journals publish randomized trials addressing a wide range of clinical topics. Randomized trials focusing on geriatric patients are not commonly published in these journals. [ABSTRACT FROM AUTHOR]

Published
2013
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180. Myokardiale Perfusionsstörung und Late Gd enhancement in der MRT bei asymptomatischen Diabetikern - Prävalenz und Einfluss auf kardiovaskuläre Ereignisse in der Heinz Nixdorf RECALL MRT-Substudie

Author

Hunold, P, primary, Nassenstein, K, additional, Schlosser, T, additional, Meyer, S, additional, Moebus, S, additional, Roggenbuck, U, additional, Lehmann, N, additional, Jöckel, KH, additional, Barkhausen, J, additional, Erbel, R, additional, and Sievers, B, additional

Published
2013
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181. Impact of Extended Primary Surgery on Suboptimally Operable Patients With Advanced Ovarian Cancer.

Author

Oseledchyk, Anton, Hunold, Lena Elisa, Mallmann, Michael R., Domröse, Christian M., Abramian, Alina, Debald, Manuel, Kaiser, Christina, Kiefer, Nicholas, Putensen, Christian, Pantelis, Dimitrios, Fimmers, Rolf, Walther Kuhn, Schäfer, Nico, and Keyver-Paik, Mignon-Denise

Abstract

Objectives: Extensive surgical efforts to achieve an optimal debulking (no residual tumor) in primary surgery of ovarian cancer are today's criterion standard in gyneco-oncologic surgery. However, it is controversial whether extensive surgery, including resections of metastases in the upper abdomen and bowel resections, is justifiable in patients with not completely operable lesions. Methods: All patients who had undergone surgery for ovarian cancer in the years 2002 to 2013 at our institution were viewed (n = 472). We retrospectively identified 278 operations for primary ovarian cancer. Ninety-six (35%) of the 278 patients showed postoperative tumor residuals and were included in this study. Results: Fifty-five (57%) of 96 patients underwent bowel resection, showing significantly higher complication rates (64% vs 39% minor complications, P = 0.017; 31% vs 9.8% severe complications, P = 0.013) compared with patients without bowel resections as well as no improvement in progression-free or overall survival (median overall survival, 19.5 vs 32.9; P = 0.382). Multiple anastomoses (Q2) were associated with higher rates for anastomotic leakage (16.7% vs 2.6%, P = 0.02) and a higher mortality (16.7% vs 0%, P = 0.04) compared with patients with only 1 anastomosis. Extensive surgery of the upper abdomen was not associated with a significant increase in complication rates. Conclusions: Because of the increased morbidity of bowel resections without any evidence for improvement of survival, we suggest to restrain from further resection of intestines if an optimal debulking seems not feasible after removal of the major tumor bulk. [ABSTRACT FROM AUTHOR]

Published
2016
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194. Konsensusempfehlungen der DRG/DGK/DGPK zum Einsatz der Herzbildgebung mit Computertomografie und Magnetresonanztomografie

Author

Achenbach, S., additional, Barkhausen, J., additional, Beer, M., additional, Beerbaum, P., additional, Dill, T., additional, Eichhorn, J., additional, Fratz, S., additional, Gutberlet, M., additional, Hoffmann, M., additional, Huber, A., additional, Hunold, P., additional, Klein, C., additional, Krombach, G., additional, Kreitner, K.-F., additional, Kühne, T., additional, Lotz, J., additional, Maintz, D., additional, Mahrholdt, H., additional, Merkle, N., additional, Messroghli, D., additional, Miller, S., additional, Paetsch, I., additional, Radke, P., additional, Steen, H., additional, Thiele, H., additional, Sarikouch, S., additional, and Fischbach, R., additional

Published
2012
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198. Leakage of Hepaticojejunal Anastomosis: Radiological Interventional Therapy

Author

May, Katharina and Hunold, Peter

Abstract

Background:Hepaticojejunostomy is an established procedure accompanying liver resection as well as hepatobiliary and pancreatic surgery. Typical complications requiring radiological intervention are abscesses and anastomosis leakage. Biliary obstruction and strictures are less frequent indications for interventional radiology since many of them can be treated endoscopically. Methods:Depending on anatomic location, underlying etiology, and complication of leakage, different procedures of interventional radiology are performed: treating abscesses through percutaneous abscess drainage (PAD), handling biliary leakage by percutaneous transhepatic biliary drainage (PTBD) after percutaneous transhepatic cholangiography (PTC), or rarely performed percutaneous stent implantation and internalization after PTC and PAD to treat biliary strictures or to cover the leak. A selective literature search was performed, taking into account recent papers of radiological interventions concerning leakage of hepaticojejunostomy. Results:Different radiological interventions for the treatment of potentially devastating complications after hepaticojejunostomy are recommended. PAD and PTBD serve either as a definite treatment or as bridging therapy until re-surgery is performed. Complications mainly concern uncontrollable bleeding during the intervention. Conclusion:Radiological interventions are safe and usable if the indication is meticulously chosen. PAD is one of the most commonly performed procedures by interventional radiologists and a well-established and safe procedure. PTC, PTBD, and biliary stent implantation are important procedures which are required if endoscopic interventions failed or cannot be performed due to postoperatively changed anatomical structures.

Published
2017
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