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151. SUN-LB056 The Pharmacological Blockade of the Splicing Factor SF3B1 Exerts Antitumor Actions in Different Endocrine-Related Cancers

Author

Enrique Gómez-Gómez, Araceli Lara-Lopez, Raúl M. Luque, Prudencio Sáez-Martínez, Juan M. Jiménez-Vacas, Alfonso Soto-Moreno, Justo P. Castaño, Aura D. Herrera-Martinez, Jesus M. Perez-Gomez, Ricardo Blazquez-Encinas, Antonio J. Montero-Hidalgo, Juan L López-Cánovas, Sergio Pedraza-Arevalo, Vicente Herrero-Aguayo, Mercedes del Rio-Moreno, Manuel D. Gahete, and Mari C Vázquez-Borrego

Subjects
Splicing factor, Tumor Biology: Translational Investigations of Endocrine Tumors and Cancer Therapies, business.industry, Endocrinology, Diabetes and Metabolism, Cancer research, Endocrine system, Medicine, Tumor Biology, business, Blockade
Abstract

The intrinsic heterogeneity of endocrine-related cancers (ERCs) hampers the identification and development of global and effective therapeutic treatments for these pathologies. However, the dysregulation of the splicing process has been postulated as a new common hallmark shared by most cancer types, since it is associated with the appearance of splicing variants with oncogenic potential (e.g. CD44v6, BCL-xs, AR-v7, SST5TMD4, In1-ghrelin). Yet, the putative alteration, pathophysiological role and potential therapeutic utility of the elements involved in the control of the splicing process [i.e. spliceosome components (SCs) and splicing factors (SFs)] remain still unknown. For this reason, we have analysed the expression levels of a representative set of SCs (n=18) and SFs (n=27) in different cohorts of ERCs [i.e. growth hormone secreting pituitary tumors (n=96); non-functioning pituitary tumors (n=23); pancreatic neuroendocrine tumors (n=20); prostate cancer (n=126); and in four in silico cohorts of liver cancer (HCC; n=445, n=115, n=75, n=45)]. Our results showed that the SF3b subunit 1 (SF3B1) gene, which encodes a protein necessary for spliceosome assembly, was consistently overexpressed in all the ERCs evaluated in this study. Interestingly, SF3B1 expression was positively correlated and associated with clinical and molecular aggressiveness features (e.g. histopathological grade, presence of metastasis, expression of oncogenic splicing variants, etc.) in these ERCs. In vitro analyses revealed that the specific blockade of SF3B1 activity, using the pladienolide-B compound, exhibited potent and relevant antitumor effects (reducing cell proliferation, migration, tumorospheres and colonies formation, hormone release and inducing apoptosis) in the vast majority of representative models of ERC cells tested herein (primary ERCs cell cultures and cell lines such as BON-1, QGP-1, LNCaP, 22Rv1, PC-3, HepG2, Hep3b or SNU-387). Remarkably, the antitumor effects of pladienolide-B treatment were further validated in vivo in that we found a significant reduction of tumor volume after 9-days of local treatment of pladienolide-B in a xenograft model of ERC. Moreover, we found that pladienolide-B treatment modulated an ample repertoire of molecular events, such as inhibition of major oncogenic signalling pathways (e.g. PI3K/AKT and JNK), modulation of the expression of key tumour markers (e.g. MKI67/CDK6/CDKN2A) and oncogenic splicing variants (e.g. AR-v7/In1-ghrelin), and regulation of the expression pattern of key components of mRNA homeostasis-associated machineries (spliceosome and SURF/EJC). In conclusion, these results indicate that SF3B1 is consistently overexpressed in different ERCs and associated to malignant features and that its pharmacological blockade with pladienolide-B could represent a novel, global and effective therapeutic approach for ERCs Unless otherwise noted, all abstracts presented at ENDO are embargoed until the date and time of presentation. For oral presentations, the abstracts are embargoed until the session begins. Abstracts presented at a news conference are embargoed until the date and time of the news conference. The Endocrine Society reserves the right to lift the embargo on specific abstracts that are selected for promotion prior to or during ENDO.

Published
2019

153. Revisión bibliográfica de metodologías de integración en las entidades del sector público en Colombia

Author

Laura Ximena Herrera Martinez and Andrea Jhoana Bernal Triana

Abstract

El objetivo de esta revision bibliografica es identificar el conocimiento sobre la gestion de la calidad en las entidades publicas colombianas y cuales son los criterios, aspectos, metodologias y herramientas utilizadas para la integracion entre dos o mas modelos. La revision bibliografica realizada estuvo enfocada en empresas del sector publico en Colombia, atendiendo a la necesidad que tiene el Estado de contribuir y mejorar la gestion institucional. Teniendo en cuenta el Modelo Integrado de Planeacion y Gestion MIPG como herramienta propuesta por el departamento de la funcion publica la cual tiene como proposito mejorar y desarrollar actividades al interior de cada entidad que fortalezcan el desempeno institucional, de igual forma, se encuentra la norma tecnica NTC ISO 9001, que busca la mejora, el enfoque por procesos, el enfoque al cliente y la satisfaccion de sus partes interesada, instrumento fundamental que deberia ser aprovechado y tenerlo como punto de partida para dar continuidad o iniciar la implementacion, desarrollo y aplicacion de mejores y buenas practicas que propendan a la mejora continua; todo lo anterior, con el fin de conocer el nivel de aceptacion y adaptacion por parte de las entidades y de los colaboradores cuando se integran varios modelos haciendo uso de las diferentes metodologias de integracion impartidas por los autores.

Published
2019
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155. Time–energy relation of the n_TOF neutron beam: energy standards revisited

Author

Lorusso, G., Colonna, N., Marrone, S., Tagliente, G., Heil, M., Cano-Ott, D., Mosconi, M., Moreau, C., Mengoni, A., Abbondanno, U., Aerts, G., Alvarez-Pol, H., Alvarez-Velarde, F., Andriamonje, S., Andrzejewski, J., Angelopoulos, A., Assimakopoulos, P., Badurek, G., Baumann, P., Bečvář, F., Benlliure, J., Berthomieux, E., Bisceglie, E., Calviño, P., Capote, R., Cennini, P., Chepel, V., Chiaveri, E., Coceva, C., Cortes, G., Cortina, D., Couture, A., Cox, J., Dababneh, S., Dahlfors, M., David, S., Dolfini, R., Domingo-Pardo, C., Duran, I., Eleftheriadis, C., Embid-Segura, M., Ferrant, L., Ferrari, A., Ferreira-Marques, R., Frais-Koelbl, H., Furman, W.I., Goncalves, I.F., Gonzalez-Romero, E., Goverdovski, A., Gramegna, F., Griesmayer, E., Gunsing, F., Haas, B., Haight, R., Herrera-Martinez, A., Ioannides, K.G., Isaev, S., Jericha, E., Käppeler, F., Kadi, Y., Karamanis, D., Ketlerov, V., Kitis, G., Koehler, P.E., Konovalov, V., Kossionides, E., Krticka, M., Leeb, H., Lindote, A., Lopes, M.I., Lozano, M., Lukic, S., Marganiec, J., Mastinu, P.F., Milazzo, P.M., Molina-Coballes, A., Neves, F., Oberhummer, H., O’Brien, S., Pancin, J., Paradela, C., Pavlik, A., Pavlopoulos, P., Perrot, L., Peskov, V., Plag, R., Plompen, A., Plukis, A., Poch, A., Policarpo, A., Pretel, C., Quesada, J.M., Rapp, W., Rauscher, T., Reifarth, R., Rosetti, M., Rubbia, C., Rudolf, G., Rullhusen, P., Salgado, J., Savvidis, E., Soares, J.C., Stephan, C., Tain, J.L., Tassan-Got, L., Tavora, L.M.N., Terlizzi, R., Tsangas, N., Vannini, G., Vaz, P., Ventura, A., Villamarin, D., Vincente, M.C., Vlachoudis, V., Vlastou, R., Voss, F., Wendler, H., Wiescher, M., and Wisshak, K.

Published
2004
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156. Measurement of the n_TOF beam profile with a micromegas detector

Author

Pancin, J., Abbondanno, U., Aerts, G., Alvarez, H., Andriamonje, S., Angelopoulos, A., Assimakopoulos, P., Bacri, C., Badurek, G., Baumann, P., Bečvář, F., Beer, H., Benlliure, J., Berthier, B., Berthoumieux, E., Boffi, S., Borcea, C., Boscolo-Marchi, E., Bustreo, N., Calvino, F., Cano-ott, D., Capote, R., Carlson, P., Cennini, P., Chepel, V., Chiaveri, E., Colonna, N., Cortes, G., Cortina, D., Couture, A., Cox, J., Dababneh, S., Dahlfors, M., David, S., Delbart, A., Derre, J., Dolfini, R., Domingo, C., Duran-Escribano, I., Eleftheriadis, C., Embid-Segura, M., Ferrant, L., Ferrari, A., Ferreira-Lourenco, L., Ferreiramarques, R., Frais-Koelbl, H., Furman, W., Giomataris, Y., Goncalves, I., Gonzalez-Romero, E., Goverdovski, A., Gramegna, F., Griesmayer, E., Gunsing, F., Haight, R., Heil, M., Herrera-Martinez, A., Ioannides, K., Janeva, N., Jeanneau, F., Jericha, E., Käppeler, F., Kadi, Y., Karamanis, D., Kelic, A., Ketlerov, V., Kitis, G., Koehler, P., Konovalov, V., Kossionides, E., Lacoste, V., Leeb, H., Lindote, A., Lopes, I., Lozano, M., Lukic, S., Markov, S., Marrone, S., Martinez-Val, J., Mastinu, P., Mengoni, A., Milazzo, P., Minguez, E., Molina-Coballes, A., Moreau, C., Neves, F., Oberhummer, H., O'brien, S., Papadopoulos, I., Papavengelou, T., Paradela, C., Pavlik, A., Pavlopoulos, P., Perez-Parra, A., Perlado, J., Peskov, V., Perrot, L., Plag, R., Plompen, A., Plukis, A., Poch, A., Policarpo, A., Pretel, C., Quesada, J., Radici, M., Raman, S., Rapp, W., Reifarth, R., Rejmund, F., Rosetti, M., Rubbia, C., Rudolf, G., Rullhusen, P., Salgado, J., Savvidis, E., Stephan, C., Tagliente, G., Tain, J., Tapia, C., Tassan-Got, L., Tavora, L., Terlizzi, R., Terrani, M., Tsangas, N., Vannini, G., Vaz, P., Ventura, A., Villamarin-Fernandez, D., Vincente-Vincente, M., Vlachoudis, V., Vlastou, R., Voss, F., Wendler, H., Wiescher, M., Wisshak, K., and Zanini, L.

Published
2004
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157. New experimental validation of the pulse height weighting technique for capture cross-section measurements

Author

Abbondanno, U, Aerts, G, Alvarez, H, Andriamonje, S, Angelopoulos, A, Assimakopoulos, P, Bacri, C.O, Badurek, G, Baumann, P, Bečvář, F, Beer, H, Benlliure, J, Berthier, B, Berthomieux, E, Boffi, S, Borcea, C, Boscolo-Marchi, E, Bustreo, N, Calviño, P, Cano-Ott, D, Capote, R, Carlson, P, Cennini, P, Chepel, V, Chiaveri, E, Coceva, C, Colonna, N, Cortes, G, Cortina, D, Couture, A, Cox, J, Dababneh, S, Dahlfors, M, David, S, Dolfini, R, Domingo-Pardo, C, Duran, I, Eleftheriadis, C, Embid-Segura, M, Ferrant, L, Ferrari, A, Ferreira-Lourenco, L, Ferreira-Marques, R, Frais-Koelbl, H, Furman, W.I, Giomataris, Y, Goncalves, I.F, Gonzalez-Romero, E, Goverdovski, A, Gramegna, F, Griesmayer, E, Gunsing, F, Haight, R, Heil, M, Herrera-Martinez, A, Ioannides, K.G, Janeva, N, Jericha, E, Käppeler, F, Kadi, Y, Karamanis, D, Kelic, A, Ketlerov, V, Kitis, G, Koehler, P.E, Konovalov, V, Kossionides, E, Lacoste, V, Leeb, H, Lindote, A, Lopes, M.I, Lozano, M, Lukic, S, Markov, S, Marrone, S, Martinez-Val, J, Mastinu, P, Mengoni, A, Milazzo, P.M, Minguez, E, Molina-Coballes, A, Moreau, C, Neves, F, Oberhummer, H, O'Brien, S, Pancin, J, Papaevangelou, T, Paradela, C, Pavlik, A, Pavlopoulos, P, Perez-Parra, A, Perlado, J.M, Perrot, L, Peskov, V, Plag, R, Plompen, A, Plukis, A, Poch, A, Policarpo, A, Pretel, C, Quesada, J.M, Radici, M, Raman, S, Rapp, W, Rauscher, T, Reifarth, R, Rejmund, F, Rosetti, M, Rubbia, C, Rudolf, G, Rullhusen, P, Salgado, J, Savvidis, E, Soares, J.C, Stephan, C, Tagliente, G, Tain, J.L, Tapia, C, Tassan-Got, L, Tavora, L.M.N, Terlizzi, R, Terrani, M, Tsangas, N, Vannini, G, Vaz, P, Ventura, A, Villamarin-Fernandez, D, Vincente-Vincente, M, Vlachoudis, V, Vlastou, R, Voss, F, Wendler, H, Wiescher, M, Wisshak, K, and Zanini, L

Published
2004
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158. Effects of Ketoconazole on ACTH-Producing and Non-ACTH-Producing Neuroendocrine Tumor Cells

Author

Herrera Martinez, Aura, Feelders, R.A., de Herder, W.W., Castano, JP (Justo), Moreno, MAG, Dogan - Oruç, Fadime, van den Dungen, Rosanna, van Koetsveld, Peter, Hofland, Leo, Herrera Martinez, Aura, Feelders, R.A., de Herder, W.W., Castano, JP (Justo), Moreno, MAG, Dogan - Oruç, Fadime, van den Dungen, Rosanna, van Koetsveld, Peter, and Hofland, Leo

Published
2019

160. Formation Patterns of Mediterranean High-Mountain Water-Bodies in Sierra-Nevada, SE Spain

Author

José Luis Díaz-Hernández and Antonio Jose Herrera-Martinez

Subjects
Mediterranean climate, lcsh:Hydraulic engineering, 010504 meteorology & atmospheric sciences, Geography, Planning and Development, Overdeepening, Aquatic Science, 010502 geochemistry & geophysics, 01 natural sciences, Biochemistry, water-bodies of Mediterranean mountains, mountain streams, lcsh:Water supply for domestic and industrial purposes, Altitude, lcsh:TC1-978, overdeepening, Glacial period, 0105 earth and related environmental sciences, Water Science and Technology, landslides, lcsh:TD201-500, geography, geography.geographical_feature_category, Landslide, Massif, Debris, hillside instability, Moraine, Physical geography, Geology
Abstract

At present, there is a lack of detailed understanding on how the factors converging on water variables from mountain areas modify the quantity and quality of their watercourses, which are features determining these areas’ hydrological contribution to downstream regions. In order to remedy this situation to some extent, we studied the water-bodies of the western sector of the Sierra Nevada massif (Spain). Since thaw is a necessary but not sufficient contributor to the formation of these fragile water-bodies, we carried out field visits to identify their number, size and spatial distribution as well as their different modelling processes. The best-defined water-bodies were the result of glacial processes, such as overdeepening and moraine dams. These water-bodies are the highest in the massif (2918 m mean altitude), the largest and the deepest, making up 72% of the total. Another group is formed by hillside instability phenomena, which are very dynamic and are related to a variety of processes. The resulting water-bodies are irregular and located at lower altitudes (2842 m mean altitude), representing 25% of the total. The third group is the smallest (3%), with one subgroup formed by anthropic causes and another formed from unknown origin. It has recently been found that the Mediterranean and Atlantic watersheds of this massif are somewhat paradoxical in behaviour, since, despite its higher xericity, the Mediterranean watershed generally has higher water contents than the Atlantic. The overall cause of these discrepancies between watersheds is not connected to their formation processes. However, we found that the classification of water volumes by the manners of formation of their water-bodies is not coherent with the associated green fringes because of the anomalous behaviour of the water-bodies formed by moraine dams. This discrepancy is largely due to the passive role of the water retained in this type of water-body as it depends on the characteristics of its hollows. The water-bodies of Sierra Nevada close to the peak line (2918 m mean altitude) are therefore highly dependent on the glacial processes that created the hollows in which they are located. Slope instability created water-bodies mainly located at lower altitudes (2842 m mean altitude), representing tectonic weak zones or accumulation of debris, which are influenced by intense slope dynamics. These water-bodies are therefore more fragile, and their existence is probably more short-lived than that of bodies created under glacial conditions.

Published
2021
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164. Memorias: Tercer Congreso Internacional: Crimen económico y fraude financiero y contable

Author

Facultad de Ciencias Contables, Corporación Universitaria Remington. Medellín, Colombia, Diego Fernando Hernández, Daniel Alberto Grajales Gaviria, Hugo Alejandro Pérez Velásquez, Corporación Universitaria Remington Facultad de Ciencias Contables, Jose Mauricio Herrera Martinez, María Reguey González Velásquez, Gabriel Antonio Gómez Ocampo, Mario de Jesús Cadavid Fonnegra, Jorge Alcides Quintero Quintero, Rubén Darío Raga Perlaza, Costa Rica Tribunal Registral Administrativo, Rogelio Cárdenas Londoño, Diego Fernando Restrepo Duque, Reinel José Guzmán Marín, Luis Gustavo Socatelli Porras, John Jairo Echeverri Arango, Institución Universitaria Escolme, Durlandy Chaverra Muñoz, Colombia Institución Universitaria de Envigado. Medellín, Institución Universitaria de Envigado, and Corporación Universitaria Remington Decano Facultad de Ciencias Contables

Published
2018
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167. Presence and functional role of KiSS/KiSS-R system in pancreatic neuroendocrine tumors (panNETs) and its relationship with clinical features and tumor behavior

Author

María A Gálvez-Moreno, Rafael Sánchez-Sánchez, Justo P Castano-Fuentes, Raul M Luque, Aura D. Herrera-Martinez, Angel J Diaz-Perez, Teresa Caro, Antonio J. Martínez-Fuentes, Emilia Alors-Perez, Raquel Serrano-Blanch, and Sergio Pedraza-Arevalo

Subjects
Functional role, media_common.quotation_subject, Kiss, medicine, Cancer research, Biology, Neuroendocrine tumors, medicine.disease, media_common
Published
2018
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169. Predicción de generación fotovoltaica con técnicas de aprendizaje supervisado

Author

Herrera Martinez, Walter, Moreno, Analía, Reybet, Ana Clara, and Saint André, Simón

Subjects
generación, Random Forest, Ingeniería, aprendizaje supervisado, Ciencias Exactas, Energía solar
Abstract

En el siguiente trabajo se realizó la predicción de la potencia generada por un conjunto de módulos fotovoltaicos ubicado en el edificio 42 del Centro Atómico Constituyentes (CAC) de la Comisión Nacional de Energía Atómica (CNEA). Se efectuó un preprocesamiento de tres años de datos de generación recolectados del inversor fotovoltaico, y posteriormente se determinó a partir de diferentes métodos de aprendizaje supervisado y su análisis, que el método con el algoritmo de Random Forest presentó el comportamiento más adecuado para realizar una predicción respecto a los datos de generación fotovoltaica reales. Una vez elegido el método de aprendizaje, se optimizaron los parámetros y se analizaron qué variables características son las más influyentes en los resultados. Finalmente se obtuvo la energía producida por el conjunto de módulos a partir de la generación predicha y se comparó con los datos reales, obteniendo coeficientes de determinación mayores a 0,9., In this work was carried out the power prediction generated by a set of photovoltaic modules located in 42´s Constituyentes Atomic Center (CAC) building of the National Atomic Energy Commission (CNEA). A preprocessing of three years of photovoltaic generation data, collected from the inverter to which the modules are connected, was conducted. Later it was determined that the method with the Random Forest algorithm presented the most suitable behavior to make a prediction regarding the real photovoltaic generation data. After choosing the learning method, parameters were optimized and analyzed to determine which characteristic variables are the most influential in the results. Finally, the energy produced by the modules was obtained from the predicted generation and it was compared with the real data, obtaining coefficients of determination greater than 0.9., Asociación Argentina de Energías Renovables y Medio Ambiente (ASADES)

Published
2018

170. Towards the design and implementation of a Smart City in Bogotá, Colombia

Author

Ochoa Guevara, Nancy Edith, primary, Díaz, Cesar O., additional, Davila Sguerra, Manuel, additional, Herrera Martinez, Marcelo, additional, Acosta Agudelo, Oscar, additional, Rios Suarez, Javier Augusto, additional, Munar Rodriguez, Aura Patricia, additional, Álzate Acuña, Gabriel Andres, additional, and López García, Andrés Camilo, additional

Published
2019
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172. SF3B1 as novel target for the treatment of multiple endocrine-related cancers

Author

Jimenez-Vacas, Juan M, primary, Lopez-Canovas, Juan L, additional, Vazquez-Borrego, Mari C, additional, Pedraza-Arevalo, Sergio, additional, del, Rio-Moreno Mercedes, additional, Herrero-Aguayo, Vicente, additional, Saez-Martinez, Prudencio, additional, Montero-Hidalgo, Antonio J, additional, Encinas, Ricardo Blazquez, additional, Lara-Lopez, Araceli, additional, Perez-Gomez, Jesus M, additional, Gomez-Gomez, Enrique, additional, Herrera-Martinez, Aura, additional, Gadelha, Monica R, additional, Castano, Justo P, additional, Gahete, Manuel D, additional, and Luque, Raul M, additional

Published
2019
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173. Biguanides exert antitumoral actions in pituitary tumor cells through AMPK-dependent and -independent mechanisms

Author

Herrera-Martinez, Aura D, primary, Vazquez-Borrego, Mari C, additional, Fuentes-Fayos, Antonio C, additional, L-Lopez, Fernando, additional, Ibanez-Costa, Alejandro, additional, Moreno, Paloma Moreno, additional, Alhambra-Exposito, Maria R, additional, Barrera-Martin, Ana, additional, Blanco-Acevedo, Cristobal, additional, Dios, Elena, additional, Venegas-Moreno, Eva, additional, Solivera, Juan, additional, Gahete, Manuel D, additional, Soto-Moreno, Alfonso, additional, Galvez-Moreno, Maria A, additional, Castano, Justo P, additional, and Luque, Raul M, additional

Published
2019
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174. Quality of life in patients undergoing bariatric surgery

Author

Merino-Molina, Sara, primary, Rebollo-Roman, Angel, additional, Herrera-Martinez, Aura-Dulcinea, additional, Alcantara-Laguna, Maria-Dolores, additional, Munoz-Jimenez, Concepcion, additional, Manzano-Garcia, Gregorio, additional, Calanas-Continente, Alfonso, additional, and Molina-Puerta, Maria-Jose, additional

Published
2019
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175. A new generation somatostatin-dopamine chimeric analogue exerts potent antitumoral actions on primary pituitary neuroendocrine tumor cells

Author

Alors-Perez, Emilia, primary, Vazquez-Borrego, Mari C, additional, L-Lopez, Fernando, additional, Galvez-Moreno, Maria A, additional, Fuentes-Fayos, Antonio C, additional, Venegas-Moreno, Eva, additional, Herrera-Martinez, Aura D, additional, Blanco-Acevedo, Cristobal, additional, Solivera, Juan, additional, Landsman, Tanya, additional, D, Gahete Manuel, additional, Soto-Moreno, Alfonso, additional, Culler, Michael D, additional, Castano, Justo P, additional, and Luque, Raul M, additional

Published
2019
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176. The splicing factor NOVA1 is overexpressed in pancreatic neuroendocrine tumors and related to increased aggressiveness and malignancy

Author

Pedraza-Arevalo, Sergio, primary, Alors-Perez, Emilia, additional, Herrera-Martinez, Aura D., additional, Blazquez-Encinas, Ricardo, additional, Sanchez-Sanchez, Rafael, additional, Ortega-Salas, Rosa, additional, Serrano-Blanch, Raquel, additional, Gahete, Manuel D., additional, Luque, Raul M, additional, and Castano, Justo P, additional

Published
2019
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178. Measurements of high-energy neutron-induced fission ofnatPb and 209Bi

Author

Couture A., Cortes G., Colonna N., Chiaveri E., Chepel V., Cennini P., Carrapiço C., Capote R., Cano-Ott D., Calviani M., Calviño F., Berthoumieux E., Becvár F., Baumann P., Badurek G., Assimakopoulos P., Andrzejewski J., Andriamonje S., Álvarez-Velarde F., Álvarez H., Aerts G., Abbondanno U., Trubert D., Stephan C., Paradela C., Le Naour C., Isaev S., Ferrant L., Duran I., Berthier B., Audouin L., Tassan-Got L., Tarrío D., Cox J., Dahlfors M., David S., Dillmann I., Domingo-Pardo C., Dridi W., Eleftheriadis C., Embid-Segura M., Ferrari A., Ferreira-Marques R., Fujii K., Furman W., Gonçalves I., González-Romero E., Gramegna F., Guerrero C., Gunsig F., Haas B., Haight R., Heil M., Herrera-Martinez A., Igashira M., Jericha E., Kadi Y., Käppeler F., Karadimos D., Karamanis D., Kerveno M., Koehler P., Kossionides E., Krticka M., Lampoudis C., Leeb H., Lindote A., Lopes I., Lozano M., Lukic S., Marganiec J., Marrone S., Martínez T., Massimi C., Mastinu P., Mengoni A., Milazzo P.M., Moreau C., Mosconi M., Neves F., Oberhummer H., O’Brien S., Oshima M., Pancin J., Papachristodoulou C., Papadopoulos C., Patronis N., Pavlik A., Pavlopoulos P., Perrot L., Pigni M.T., Plag R., Plompen A., Plukis A., Poch A., Praena J., Pretel C., Quesada J., Rauscher T., Reifarth R., Rubbia C., Rudolf G., Rullhusen P., Salgado J., Santos C., Sarchiapone L., Savvidis I., Tagliente G., Tain J.L., Tavora L., Terlizzi R., Vannini G., Vaz P., Ventura A., Villamarin D., Vicente M.C., Vlachoudis V., Vlastou R., Voss F., Walter S., Wiescher M., and Wisshak K.

Subjects
Physics, QC1-999
Abstract

The CERN Neutron Time-Of-Flight (n_TOF) facility is well suited to measure low cross sections as those of neutron-induced fission in subactinides. The cross section ratios of natPb and 209Bi relative to 235U and 238U were measured using PPAC detectors and a fragment coincidence method that allows us to identify the fission events. The present experiment provides first results for neutron-induced fission up to 1 GeV. Good agreement is found with previous experimental data below 200 MeV. The comparison with proton-induced fission indicates that the limiting regime where neutron-induced and proton-induced fission reach equal cross sections is close to 1 GeV.

Published
2010
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179. Development of a perforated panel for acoustic conditioning based on Colombian guadua fiber (Guadua angustifolia Kunth)

Author

Paez Soto, Dario Alfonso, Herrera Fernandez, Luis Jorge, Acosta Agudelo, Oscar Esneider, Garcia Bustos, Shymmy Wilbermer, Herrera Martinez, Marcelo, Paez Soto, Dario Alfonso, Herrera Fernandez, Luis Jorge, Acosta Agudelo, Oscar Esneider, Garcia Bustos, Shymmy Wilbermer, and Herrera Martinez, Marcelo

Abstract

The present research is about the practical implementation of a perforated panel for acoustic conditioning, manufactured with guadua, a typical Colombian fiber. The developed panel is checked for its acoustic conditioning properties. Guadua is an attractive natural resource with great potential for renovation and use in sustainable construction. Here, its acoustic absorption coefficient is measured and validated; finally, a physical panel is built for acoustic conditioning purposes

Published
2018

180. Renewable Insulation materials constructed from Colombian materials according to the principles of Sustainable Development: a review of possibilities

Author

Herrera Martinez, Marcelo, Paez Soto, Dario Alfonso, Herrera Martinez, Marcelo, and Paez Soto, Dario Alfonso

Abstract

The growing demand for building materials requires the development of environmentally friendly materials with excellent use properties and reasonable prices. One of the major objectives of materials research in the construction industry is the use of renewable resources from waste materials from industries for the development of new building materials. The current trend of thermal insulation of buildings has resulted in the development of materials for insulation based on renewable resources of agriculture. This article describes the research and development of insulation materials based on natural fibres of agricultural origin; in particular, guadua fibres, sugar cane, hemp, flax and jute.

Published
2018

181. 237Np(n,f) Cross Section: New Data and Present Status

Author

B. Haas, I. Savvidis, C. Lampoudis, A. Pavlik, C. Domingo-Pardo, G. Cortes, Martin Heil, P. Cennini, S. David, D. Tarrío, D. Cano-Ott, W. Dridi, Roberto Capote, P.A. Assimakopoulos, M. Mosconi, S. O'Brien, G. Tagliente, Marco Calviani, M. Oshima, R. Terlizzi, Corrie S. Moreau, S. Walter, J. Andrzejewski, L. Tavora, Ralf Plag, F. Calviño, H. Leeb, J. Salgado, Isabel Lopes, P. Rullhusen, J. Marganiec, S. Andriamonje, A. Poch, C. Santos, E. Kossionides, E. Chiaveri, K. Wisshak, P. F. Mastinu, A. J. M. Plompen, Christoph A. Stephan, J. Pancin, A. Herrera-Martinez, N. Patronis, A. Ventura, F. Gunsing, D. Trubert, L. Ferrant, Cristian Massimi, Javier Praena, I. Duran, Arnaud Ferrari, G. Aerts, M. Dahlfors, Y. Kadi, R. C. Haight, M. Embid-Segura, P. Vaz, Rene Reifarth, H. Álvarez, S. Lukic, D. Villamarin, Alberto Mengoni, James L. Cox, C. Paradela, M. C. Vicente, C. Eleftheriadis, Thomas Rauscher, Aaron Couture, M. Krtička, S. Isaev, J. M. Quesada, Manuel Lozano, L. Tassan-Got, Carlos Guerrero, U. Abbondanno, J. L. Tain, L. Audouin, B. Berthier, P. E. Koehler, L. Sarchiapone, D. Karadimos, R. Ferreira-Marques, T. Martinez, Heinz Oberhummer, E. Jericha, C. Le Naour, E. González-Romero, P. Pavlopoulos, Michael Wiescher, F. Voss, F. Becvar, W.I. Furman, F. Alvarez-Velarde, R. Vlastou, Marco T. Pigni, Nicola Colonna, Masayuki Igashira, E. Berthoumieux, Gerald Badurek, A. Plukis, Vasilis Vlachoudis, C. A. Papachristodoulou, F. Gramegna, K. Fujii, C. T. Papadopoulos, A. Lindote, C. Rubbia, C. Pretel, F. Käppeler, Isabel S. Gonçalves, S. Marrone, M. Kerveno, F. Neves, P. M. Milazzo, L. Perrot, V. Chepel, G. Rudolf, P. Baumann, G. Vannini, C. Carrapiço, D. Karamanis, I. Dillmann, Universitat Politècnica de Catalunya. Departament de Física i Enginyeria Nuclear, Universitat Politècnica de Catalunya. GREENER - Grup de recerca d'estudis energètics i de les radiacions, Paradela C., Tassan-Got L., Audouin L., Berthier B., Ferrant L., Isaev S., Naour C. Le, Stephan C., Trubert D., David S., Duran I., Tarrio D., Alvarez H., Abbondanno U., Fujii K., Milazzo P. M., Moreau C., Aerts G., Alvarez-Velarde F., Cano-Ott D., Embid-Segura M., Gonzalez-Romero E., Guerrero C., Martinez T., Villamarin D., Vicente M. C., Andriamonje S., Berthoumieux E., Dridi W., Gunsing F., Pancin J., Perrot L., Plukis A., Andrzejewski J., Marganiec J., Assimakopoulos P., Karadimos D., Karamanis D., Papachristodoulou C., Patronis N., Badurek G., Jericha E., Leeb H., Oberhummer H., Pigni M. T., Baumann P., Kerveno M., Lukic S., Rudolf G., Becvar F., Krticka M., Calvino F., Cortes G., Poch A., Pretel C., Calviani M., Gramegna F., Mastinu P., Praena J., Capote R., Carrapico C., Cennini P., Chiaveri E., Dahlfors M., Ferrari A., Herrera-Martinez A., Kadi Y., Sarchiapone L., Vlachoudis V., Chepel V., Ferreira-Marques R., Lindote A., Lopes I., Neves F., Colonna N., Tagliente G., Terlizzi R., Couture A., Cox J., Marrone S., Obrien S., Wiescher M., Dillmann I., Heil M., Kappeler F., Mosconi M., Voss F., Walter S., Wisshak K., Domingo-Pardo C., Plag R., Plompen A., Tain J. L., Eleftheriadis C., Savvidis I., Furman W., Goncalves I., Salgado J., Santos C., Tavora L., Vaz P., Haas B., Haight R., Reifarth R., Igashira M., Koehler P., Kossionides E., Lampoudis C., Lozano M., Quesada J., Massimi C., Vannini G., Mengoni A., Oshima M., Papadopoulos C., Pavlik A., Pavlopoulos P., Vlastou R., Rauscher T., Rubbia C., Rullhusen P., Ventura A., Institut de Physique Nucléaire d'Orsay (IPNO), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Aval du cycle et Energie Nucléaire (ACEN), Centre d'Etudes Nucléaires de Bordeaux Gradignan (CENBG), Université Sciences et Technologies - Bordeaux 1-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Sciences et Technologies - Bordeaux 1-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département Recherches Subatomiques (DRS-IPHC), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Pôle Universitaire Léonard de Vinci, Pôle Universitaire Léonard de Vinci (PULV), nTOF, Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Sciences et Technologies - Bordeaux 1 (UB)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Sciences et Technologies - Bordeaux 1 (UB)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), and Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Energies::Energia nuclear [Àrees temàtiques de la UPC], Physics, neutron fission cross section, Np-237, Fission, Nuclear data, General Physics and Astronomy, Nuclear energy, 020206 networking & telecommunications, Energies::Energia nuclear::Reactors nuclears de fissió [Àrees temàtiques de la UPC], 02 engineering and technology, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], Nuclear physics, TIME-OF-FLIGHT, Cross section (physics), Fusion reactors, Reactors nuclears, n TOF experiment, 0202 electrical engineering, electronic engineering, information engineering, Energia nuclear, 020201 artificial intelligence & image processing, Energy (signal processing), Neutron-induced ssion reactions
Abstract

In this document, we present the nal result obtained at the n TOF experiment for the neutron- induced ssion cross section of the 237Np, from the ssion threshold up to 1 GeV. The method applied to get this result is brie y discussed. n TOF data are compared to the last experimental measurements using other TOF facilities or the surrogate method, reported experiments performed with monoenergetic sources and the FISCAL systematic, including a discussion about the existing discrepancies.

Published
2011
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182. High-energy Neutron-induced Fission Cross Sections of Natural Lead and Bismuth-209

Author

D. Tarrio, L. Tassan-Got, L. Audouin, B. Berthier, L. Ferrant, S. Isaev, C. Le Naour, C. Stephan, D. Trubert, S. David, I. Duran, C. Paradela, H. Alvarez, U. Abbondanno, K. Fujii, P. M. Milazzo, C. Moreau, G. Aerts, F. Alvarez-Velarde, D. Cano-Ott, M. Embid-Segura, E. Gonzalez-Romero, C. Guerrero, T. Martinez, D. Villamarin, M. C. Vicente, S. Andriamonje, E. Berthoumieux, W. Dridi, F. Gunsig, J. Pancin, L. Perrot, A. Plukis, J. Andrzejewski, J. Marganiec, P. Assimakopoulos, D. Karadimos, D. Karamanis, C. Papachristodoulou, N. Patronis, G. Badurek, E. Jericha, H. Leeb, H. Oberhummer, M. T. Pigni, P. Baumann, M. Kerveno, S. Lukic, G. Rudolf, F. Becvar, M. Krticka, F. Calvino, G. Cortes, A. Poch, C. Pretel, M. Calviani, F. Gramegna, P. Mastinu, J. Praena, R. Capote, C. Carrapico, P. Cennini, E. Chiaveri, M. Dahlfors, A. Ferrari, I. Goncalves, A. Herrera-Martinez, Y. Kadi, L. Sarchiapone, V. Vlachoudis, V. Chepel, R. Ferreira-Marques, A. Lindote, I. Lopes, F. Neves, N. Colonna, G. Tagliente, R. Terlizzi, A. Couture, J. Cox, S. Marrone, S. O'brien, M. Wiescher, I. Dillmann, M. Heil, F. Kappeler, M. Mosconi, F. Voss, S. Walter, K. Wisshak, C. Domingo-Pardo, R. Plag, A. Plompen, J. L. Tain, C. Eleftheriadis, I. Savvidis, W. Furman, B. Haas, R. Haight, R. Reifarth, M. Igashira, P. Koehler, E. Kossionides, C. Lampoudis, M. Lozano, J. Quesada, C. Massimi, G. Vannini, A. Mengoni, M. Oshima, C. Papadopoulos, A. Pavlik, P. Pavlopoulos, R. Vlastou, T. Rauscher, C. Rubbia, P. Rullhusen, J. Salgado, C. Santos, L. Tavora, P. Vaz, A. Ventura, Universitat Politècnica de Catalunya. Departament de Física i Enginyeria Nuclear, Universitat Politècnica de Catalunya. GREENER - Grup de recerca d'estudis energètics i de les radiacions, Institut de Physique Nucléaire d'Orsay (IPNO), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Aval du cycle et Energie Nucléaire (ACEN), Centre d'Etudes Nucléaires de Bordeaux Gradignan (CENBG), Université Sciences et Technologies - Bordeaux 1-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Sciences et Technologies - Bordeaux 1-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département Recherches Subatomiques (DRS-IPHC), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Pôle Universitaire Léonard de Vinci, Pôle Universitaire Léonard de Vinci (PULV), nTOF, Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Sciences et Technologies - Bordeaux 1 (UB)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Sciences et Technologies - Bordeaux 1 (UB)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Tarrno D., Tassan-Got L., Audouin L., Berthier B., Ferrant L., Isaev S., Naour C. Le, Stephan C., Trubert D., David S., Duran I., Paradela C., Alvarez H., Abbondanno U., Fujii K., Milazzo P. M., Moreau C., Aerts G., Alvarez-Velarde F., Cano-Ott D., Embid-Segura M., Gonzalez-Romero E., Guerrero C., Martinez T., Villamarin D., Vicente M. C., Andriamonje S., Berthoumieux E., Dridi W., Gunsig F., Pancin J., Perrot L., Plukis A., Andrzejewski J., Marganiec J., Assimakopoulos P., Karadimos D., Karamanis D., Papachristodoulou C., Patronis N., Badurek G., Jericha E., Leeb H., Oberhummer H., Pigni M. T., Baumann P., Kerveno M., Lukic S., Rudolf G., Becvar F., Krticka M., Calvino F., Cortes G., Poch A., Pretel C., Calviani M., Gramegna F., Mastinu P., Praena J., Capote R., Carrapico C., Cennini P., Chiaveri E., Dahlfors M., Ferrari A., Goncalves I., Herrera-Martinez A., Kadi Y., Sarchiapone L., Vlachoudis V., Chepel V., Ferreira-Marques R., Lindote A., Lopes I., Neves F., Colonna N., Tagliente G., Terlizzi R., Couture A., Cox J., Marrone S., Obrien S., Wiescher M., Dillmann I., Heil M., Kappeler F., Mosconi M., Voss F., Walter S., Wisshak K., Domingo-Pardo C., Plag R., Plompen A., Tain J. L., Eleftheriadis C., Savvidis I., Furman W., Haas B., Haight R., Reifarth R., Igashira M., Koehler P., Kossionides E., Lampoudis C., Lozano M., Quesada J., Massimi C., Vannini G., Mengoni A., Oshima M., Papadopoulos C., Pavlik A., Pavlopoulos P., Vlastou R., Rauscher T., Rubbia C., Rullhusen P., Salgado J., Santos C., Tavora L., Vaz P., and Ventura A.

Subjects
Pb-nat(n, Fission, Nuclear data, Nuclear Theory, General Physics and Astronomy, chemistry.chemical_element, f), Energies::Energia nuclear::Reactors nuclears de fissió [Àrees temàtiques de la UPC], [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], 7. Clean energy, Bismuth, Nuclear physics, Nuclear reactors, Reactors nuclears, Neutron, Spallation, Nuclear Experiment, EMERGING NUCLEAR TECHNOLOGIES, Neutron-induced ssion reactions, Energies::Energia nuclear [Àrees temàtiques de la UPC], Physics, Cluster decay, Nuclear energy, Bi-209(n, n TOF facility, TIME-OF-FLIGHT, chemistry, Spallation neutron source, Energia nuclear, Neutron source, PPAC fission detector, Spallation Neutron Source
Abstract

The CERN Neutron Time-Of-Flight (n-TOF) facility is well suited to measure small neutron-induced fission cross sections, as those of subactinides. The cross section ratios of {sup nat}Pb and {sup 209}Bi relative to {sup 235}U and {sup 238}U were measured using PPAC detectors. The fragment coincidence method allows to unambiguously identify the fission events. The present experiment provides the first results for neutron-induced fission up to 1 GeV for {sup nat}Pb and {sup 209}Bi. A good agreement with previous experimental data below 200 MeV is shown. The comparison with proton-induced fission indicates that the limiting regime where neutron-induced and proton-induced fission reach equal cross section is close to 1 GeV.

Published
2011
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185. Diagnosis of cystic fibrosis related diabetes

Author

Aura-Dulcinea Herrera-Martinez, Jose-Manuel Vaquero-Barrios, Alfonso Calanas-Continente, Paloma Moreno-Moreno, Angel Rebollo-Roman, and Ana Barrera-Martin

Subjects
medicine.medical_specialty, business.industry, Internal medicine, Cystic fibrosis-related diabetes, medicine, medicine.disease, business, Gastroenterology
Published
2017
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186. Characterization of young Mexican patients with breast cancer who underwent oocyte/embryo preservation

Author

Villarreal-Garza, Cynthia Mayte, primary, Alejandra, Platas, additional, Juan Enrique, Bargallo-Rocha, additional, Melina, Miaja, additional, Alan, Fonseca, additional, Edna A, Lopez-Martinez, additional, Jose Felipe, Muñoz-Lozano, additional, Bertha Alejandra, Martinez-Cannon, additional, Andrea, Castro-Sanchez, additional, Marytere, Herrera-Martinez, additional, Manuel Rolando, Garcia Garza, additional, Carlos, Navarro-Martinez, additional, and Alejandro, Mohar, additional

Published
2018
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188. Presence and functional role of KiSS/KiSS-R system in pancreatic neuroendocrine tumors (panNETs) and its relationship with clinical features and tumor behavior

Author

Alors-Perez, Emilia, primary, Pedraza-Arevalo, Sergio, additional, Herrera-Martinez, Aura, additional, Diaz-Perez, Angel J, additional, Caro, Teresa, additional, Serrano-Blanch, Raquel, additional, Sanchez-Sanchez, Rafael, additional, Galvez-Moreno, Maria Angeles, additional, Castano-Fuentes, Justo P, additional, Luque, Raul M, additional, and Martinez-Fuentes, Antonio J, additional

Published
2018
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191. Evaluation of the Microlocal Wind Power Potential for the Operation of a University Wind Turbine

Author

Villamarín, Luis Fernando, Mayorga Betancourt, Manuel Alejandro, Herrera Martinez, Marcelo, Hernández, Olga Camila, Sánchez, Ricardo, Villamarín, Luis Fernando, Mayorga Betancourt, Manuel Alejandro, Herrera Martinez, Marcelo, Hernández, Olga Camila, and Sánchez, Ricardo

Abstract

The research deals with the estimation of the available wind’s potential on the building terrace, at the P-headquarter of the Universidad ECCI of Colombia, and from the results obtained consequently verify if the wind conditions are conducive to the operation of a wind micro-turbine, currently unused. The methodology is based on the wind speed estimation; applying the velocity potential’s law to the records captured, between the 1st of January and the 24th of March, 2015, by the weather station of the National University of Colombia. Once the speed of the wind is estimated in the study area, a frequency velocity distribution is performed and the graphical method is applied to determine the scale, c and shape parameters, k that allow the characterization of the function of the Weibull distribution in the study area. Finally, based on the micro turbine’s specifications, the power that could be usable is estimated and it is theoretically evaluated if the wind conditions are optimal for its operation. Although wind speed data were recorded in the study area, using the Universidad ECCI weather station, they were only used as a benchmark for the estimated velocities. The estimated values of the useful power and the wind power density for the wind micro-turbine, operating at a wind speed of , which represents approximately the average value of the wind speed (obtained with the scale factor of the Weibull function), are respectively and ., La investigación consiste en estimar el potencial eólico disponible en la terraza del edificio, sede P de la Universidad ECCI y verificar, a partir de los resultados obtenidos, sí las condiciones de viento son propicias para el funcionamiento de una microturbina eólica, actualmente inutilizada. La metodología, se fundamenta en la estimación de velocidad de viento; aplicando la ley potencial a los registros de velocidades capturados, entre el 1 de enero y el 24 de marzo de 2015, por la estación meteorológica de la Universidad Nacional. Una vez estimada la velocidad de viento en la zona de estudio, se realiza una distribución de velocidades de frecuencia y se procede, aplicando el método gráfico, a determinar los parámetros de escala, c y de forma, k que permiten caracterizar la función de distribución de Weibull en la zona de estudio. Finalmente y a partir de algunas especificaciones de la micro-turbina, se estima su potencia útil y se evalúa, teóricamente, si las condiciones de viento son óptimas para su funcionamiento. Aunque, se registraron datos de velocidad de viento en la zona de estudio empleando la estación meteorológica de la Universidad ECCI, únicamente fueron utilizados como patrón de comparación para las velocidades estimadas. Los valores estimados de la potencia útil y la densidad de potencia del viento, para la micro-turbina eólica, operando a un velocidad de viento de 4.0m/s, que representa aproximadamente el valor promedio de la velocidad de viento (obtenido con el factor de escala de la función de Weibull), son respectivamente 41 W y 0.226 W/m^2.

Published
2017

192. Detección, estimación y problemas inversos con sistemas sonar

Author

Vallejo, Felipe A, Rodríguez, Belman Jahir, Herrera Martinez, Marcelo, Vallejo, Felipe A, Rodríguez, Belman Jahir, and Herrera Martinez, Marcelo

Abstract

The present work introduces the reader to the basic theory used to optimally extract and process information in passive and active sonar systems. In particular, the typical problems addressed when implementing sonar technology systems are reviewed. The work also covers the basic statistical theory that is used in acoustic signal processing and the behavior of the receiving operating characteristics (ROC) when dealing with probability density functions for noise and signal in presence of noise with varying standard deviations. Finally, we review the underlying theory of inverse problems and model based matched field processing that will be implemented in a future visualization system for under water applications., El objetivo del presente trabajo es hacer una introducción a la teoría básica utilizada para extraer información y cómo hacer un procesamiento de señales óptimo para sistemas SoNAR activos o pasivos. En especial, se revisa cómo se catalogan los problemas típicos que se tratan en sistemas tipo sonar. Se revisa la teoría estadística que se usa en el procesamiento de señal acústica y se estudia el comportamiento de las curvas características de operación cuando se varía la varianza de las distribuciones de probabilidad de ruido y de señal en presencia del ruido. Por último, se revisa la teoría de fondo de los problemas inversos y el procesamiento de campo ajustado para aplicarlo en un futuro a un sistema de visualización acuática en condiciones de poca visibilidad.

Published
2017

194. Multiport cyclical fibre-optical switch

Author

Sergei N. Khotiaintsev, A. R. Sanchez-Ramirez, H. J. Guzman Olguin, M. A. Zuniga Bravo, E. Ovando-Shelley, M. C. Lopez Bautista, F. Galvez-Mendoza, D. M. Martinez-Gonzalez, and A. Herrera Martinez

Subjects
Optical fiber, Materials science, business.industry, Optical cross-connect, Physics::Optics, 02 engineering and technology, Optical modulation amplitude, 021001 nanoscience & nanotechnology, Optical burst switching, 01 natural sciences, Optical switch, Waveguide (optics), law.invention, 010309 optics, Amplitude modulation, Optics, law, Optical transistor, 0103 physical sciences, 0210 nano-technology, business
Abstract

We present a layout and operational characteristics of an optical switch that performs a cyclic switching of an input port to multiple output ports by means of a metal-clad optical fibre cantilever in oscillatory motion at its natural resonance frequency. The oscillatory motion of the fibre is produced by the force of the alternating electric or magnetic field. The switch is intended for use in large arrays of fibre-optical sensors with binary-type amplitude modulation of optical signals, such as employed in liquid-level measurement and structural damage detection.

Published
2016
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195. Neutron-induced fission cross section of U-234 measured at the CERN n_TOF facility

Author

D. Karadimos, R. Vlastou, K. Ioannidis, P. Demetriou, M. Diakaki, V. Vlachoudis, P. Pavlopoulos, V. Konovalov, U. Abbondanno, G. Aerts, H. Alvarez, F. Alvarez Velarde, S. Andriamonje, J. Andrzejewski, P. Assimakopoulos, L. Audouin, G. Badurek, P. Baumann, F. Becvar, E. Berthoumieux, F. Calvino, D. Cano Ott, R. Capote, A. C. de, V. Chepel, E. Chiaveri, N. Colonna, G. Cortes, A. Couture, J. Cox, S. David, R. Dolfini, C. Domingo Pardo, A. Dorochenko, W. Dridi, I. Duran, C. Eleftheriadis, M. Embid Segura, L. Ferrant, A. Ferrari, R. Ferreira Marques, L. Fitzpatrick, H. Frais Koelbl, K. Fuji, W. Furman, I. Goncalves, R. Gallino, P. Cennini, E. Gonzalez Romero, A. Goverdovski, F. Gramegna, E. Griesmayer, C. Guerrero, F. Gunsing, B. Haas, R. Haight, M. Heil, A. Herrera Martinez, M. Igashira, S. Isaev, E. Jericha, Y. Kadi, F. Kaeppeler, D. Karamanis, M. Kerveno, V. Ketlerov, P. Koehler, D. Kolokolov, M. Krticka, C. Lamboudis, H. Leeb, A. Lindote, I. Lopes, M. Lozano, S. Lukic, J. Marganiec, L. Marques, S. Marrone, P. Mastinu, A. Mengoni, P. M. Milazzo, C. Moreau, M. Mosconi, F. Neves, H. Oberhummer, S. O'Brien, M. Oshima, J. Pancin, C. Papadopoulos, C. Paradela, N. Patronis, A. Pavlik, L. Perrot, R. Plag, A. Plompen, A. Plukis, A. Poch, C. Pretel, J. Quesada, T. Rauscher, R. Reifarth, M. Rosetti, C. Rubbia, G. Rudolf, P. Rullhusen, J. Salgado, L. Sarchiapone, I. Savvidis, M. Sedysheva, K. Stamoulis, C. Stephan, G. Tagliente, J. L. Tain, L. Tassan Got, L. Tavora, R. Terlizzi, A. Tsinganis, P. Vaz, A. Ventura, D. Villamarin, M. C. Vincente, F. Voss, H. Wendler, M. Wiescher, K. Wisshak, MASSIMI, CRISTIAN, VANNINI, GIANNI, D. Karadimo, R. Vlastou, K. Ioannidi, P. Demetriou, M. Diakaki, V. Vlachoudi, P. Pavlopoulo, V. Konovalov, U. Abbondanno, G. Aert, H. Alvarez, F. Alvarez-Velarde, S. Andriamonje, J. Andrzejewski, P. Assimakopoulo, L. Audouin, G. Badurek, P. Baumann, F. Becvar, E. Berthoumieux, F. Calvino, D. Cano-Ott, R. Capote, A. C. de, V. Chepel, E. Chiaveri, N. Colonna, G. Corte, A. Couture, J. Cox, S. David, R. Dolfini, C. Domingo-Pardo, A. Dorochenko, W. Dridi, I. Duran, C. Eleftheriadi, M. Embid-Segura, L. Ferrant, A. Ferrari, R. Ferreira-Marque, L. Fitzpatrick, H. Frais-Koelbl, K. Fuji, W. Furman, I. Goncalve, R. Gallino, P. Cennini, E. Gonzalez-Romero, A. Goverdovski, F. Gramegna, E. Griesmayer, C. Guerrero, F. Gunsing, B. Haa, R. Haight, M. Heil, A. Herrera-Martinez, M. Igashira, S. Isaev, E. Jericha, Y. Kadi, F. Kaeppeler, D. Karamani, M. Kerveno, V. Ketlerov, P. Koehler, D. Kolokolov, M. Krticka, C. Lamboudi, H. Leeb, A. Lindote, I. Lope, M. Lozano, S. Lukic, J. Marganiec, L. Marque, S. Marrone, C. Massimi, P. Mastinu, A. Mengoni, P. M. Milazzo, C. Moreau, M. Mosconi, F. Neve, H. Oberhummer, S. O'Brien, M. Oshima, J. Pancin, C. Papadopoulo, C. Paradela, N. Patroni, A. Pavlik, L. Perrot, R. Plag, A. Plompen, A. Pluki, A. Poch, C. Pretel, J. Quesada, T. Rauscher, R. Reifarth, M. Rosetti, C. Rubbia, G. Rudolf, P. Rullhusen, J. Salgado, L. Sarchiapone, I. Savvidi, M. Sedysheva, K. Stamouli, C. Stephan, G. Tagliente, J. L. Tain, L. Tassan-Got, L. Tavora, R. Terlizzi, A. Tsingani, G. Vannini, P. Vaz, A. Ventura, D. Villamarin, M. C. Vincente, F. Vo, H. Wendler, M. Wiescher, and K. Wisshak

Subjects
MINOR ACTINIDES TRANSMUTATIONS, Nuclear Experiment, NEUTRON TIME OF FLIGHT, NEUTRON INDUCED FISSION
Abstract

The neutron-induced fission cross section of U234 has been measured at the CERN n_TOF facility relative to the standard fission cross section of U235 from 20 keV to 1.4 MeV and of U238 from 1.4 to 200 MeV. A fast ionization chamber (FIC) was used as a fission fragment detector with a detection efficiency of no less than 97%. The high instantaneous flux and the low background characterizing the n_TOF facility resulted in wide-energy-range data (0.02 to 200 MeV), with high energy resolution, high statistics, and systematic uncertainties bellow 3%. Previous investigations around the energy of the fission threshold revealed structures attributed to β-vibrational levels, which have been confirmed by the present measurements. Theoretical calculations have been performed, employing the talys code with model parameters tuned to fairly reproduce the experimental data.

Published
2014

196. Measurement and analysis of the Am-243 neutron capture cross section at the n_TOF facility at CERN

Author

E. Mendoza, D. Cano Ott, C. Guerrero, E. Berthoumieux, U. Abbondanno, G. Aerts, F. Alvarez Velarde, S. Andriamonje, J. Andrzejewski, P. Assimakopoulos, L. Audouin, G. Badurek, J. Balibrea, P. Baumann, F. Becvar, F. Belloni, F. Calvino, M. Calviani, R. Capote, C. Carrapico, A. C. de, P. Cennini, V. Chepel, E. Chiaveri, N. Colonna, G. Cortes, A. Couture, J. Cox, M. Dahlfors, S. David, I. Dillmann, R. Dolfini, C. Domingo Pardo, W. Dridi, I. Duran, C. Eleftheriadis, L. Ferrant, A. Ferrari, R. Ferreira Marques, L. Fitzpatrick, H. Frais Koelbl, K. Fujii, W. Furman, I. Goncalves, E. Gonzalez Romero, A. Goverdovski, F. Gramegna, E. Griesmayer, F. Gunsing, B. Haas, R. Haight, M. Heil, A. Herrera Martinez, M. Igashira, S. Isaev, E. Jericha, F. Kaeppeler, Y. Kadi, D. Karadimos, D. Karamanis, V. Ketlerov, M. Kerveno, P. Koehler, V. Konovalov, E. Kossionides, M. Krticka, C. Lampoudis, H. Leeb, A. Lindote, S. L. Meo, I. Lopes, R. Lossito, M. Lozano, S. Lukic, J. Marganiec, L. Marques, S. Marrone, T. Martinez, MASSIMI, CRISTIAN, P. Mastinu, A. Mengoni, P. M. Milazzo, C. Moreau, M. Mosconi, F. Neves, H. Oberhummer, S. O'Brien, M. Oshima, J. Pancin, C. Papachristodoulou, C. Papadopoulos, C. Paradela, N. Patronis, A. Pavlik, P. Pavlopoulos, L. Perrot, M. T. Pigni, R. Plag, A. Plompen, A. Plukis, A. Poch, J. Praena, C. Pretel, J. Quesada, T. Rauscher, R. Reifarth, C. Rubbia, G. Rudolf, P. Rullhusen, J. Salgado, C. Santos, L. Sarchiapone, I. Savvidis, C. Stephan, G. Tagliente, J. L. Tain, L. Tassan Got, L. Tavora, R. Terlizzi, VANNINI, GIANNI, P. Vaz, A. Ventura, D. Villamarin, M. C. Vicente, V. Vlachoudis, R. Vlastou, F. Voss, S. Walter, H. Wendler, M. Wiescher, K. Wisshak, E. Mendoza, D. Cano-Ott, C. Guerrero, E. Berthoumieux, U. Abbondanno, G. Aert, F. Alvarez-Velarde, S. Andriamonje, J. Andrzejewski, P. Assimakopoulo, L. Audouin, G. Badurek, J. Balibrea, P. Baumann, F. Becvar, F. Belloni, F. Calvino, M. Calviani, R. Capote, C. Carrapico, A. C. de, P. Cennini, V. Chepel, E. Chiaveri, N. Colonna, G. Corte, A. Couture, J. Cox, M. Dahlfor, S. David, I. Dillmann, R. Dolfini, C. Domingo-Pardo, W. Dridi, I. Duran, C. Eleftheriadi, L. Ferrant, A. Ferrari, R. Ferreira-Marque, L. Fitzpatrick, H. Frais-Koelbl, K. Fujii, W. Furman, I. Goncalve, E. Gonzalez-Romero, A. Goverdovski, F. Gramegna, E. Griesmayer, F. Gunsing, B. Haa, R. Haight, M. Heil, A. Herrera-Martinez, M. Igashira, S. Isaev, E. Jericha, F. Kaeppeler, Y. Kadi, D. Karadimo, D. Karamani, V. Ketlerov, M. Kerveno, P. Koehler, V. Konovalov, E. Kossionide, M. Krticka, C. Lampoudi, H. Leeb, A. Lindote, S. L. Meo, I. Lope, R. Lossito, M. Lozano, S. Lukic, J. Marganiec, L. Marque, S. Marrone, T. Martinez, C. Massimi, P. Mastinu, A. Mengoni, P. M. Milazzo, C. Moreau, M. Mosconi, F. Neve, H. Oberhummer, S. O'Brien, M. Oshima, J. Pancin, C. Papachristodoulou, C. Papadopoulo, C. Paradela, N. Patroni, A. Pavlik, P. Pavlopoulo, L. Perrot, M. T. Pigni, R. Plag, A. Plompen, A. Pluki, A. Poch, J. Praena, C. Pretel, J. Quesada, T. Rauscher, R. Reifarth, C. Rubbia, G. Rudolf, P. Rullhusen, J. Salgado, C. Santo, L. Sarchiapone, I. Savvidi, C. Stephan, G. Tagliente, J. L. Tain, L. Tassan-Got, L. Tavora, R. Terlizzi, G. Vannini, P. Vaz, A. Ventura, D. Villamarin, M. C. Vicente, V. Vlachoudi, R. Vlastou, F. Vo, S. Walter, H. Wendler, M. Wiescher, and K. Wisshak

Subjects
RADIATIVE NEUTRON CAPTURE, NEUTRON TIME OF FLIGHT
Abstract

Background: The design of new nuclear reactors and transmutation devices requires to reduce the present neutron cross section uncertainties of minor actinides. Purpose: Improvement of the Am243(n,γ) cross section uncertainty. Method: The Am243(n,γ) cross section has been measured at the n-TOF facility at CERN with a BaF2 total absorption calorimeter, in the energy range between 0.7 eV and 2.5 keV. Results: The Am243(n,γ) cross section has been successfully measured in the mentioned energy range. The resolved resonance region has been extended from 250 eV up to 400 eV. In the unresolved resonance region our results are compatible with one of the two incompatible capture data sets available below 2.5 keV. The data available in EXFOR and in the literature have been used to perform a simple analysis above 2.5 keV. Conclusions: The results of this measurement contribute to reduce the Am243(n,γ) cross section uncertainty and suggest that this cross section is underestimated up to 25% in the neutron energy range between 50 eV and a few keV in the present evaluated data libraries. Background: The design of new nuclear reactors and transmutation devices requires to reduce the present neutron cross section uncertainties of minor actinides. Purpose: Improvement of the Am243(n,γ) cross section uncertainty. Method: The Am243(n,γ) cross section has been measured at the n-TOF facility at CERN with a BaF2 total absorption calorimeter, in the energy range between 0.7 eV and 2.5 keV. Results: The Am243(n,γ) cross section has been successfully measured in the mentioned energy range. The resolved resonance region has been extended from 250 eV up to 400 eV. In the unresolved resonance region our results are compatible with one of the two incompatible capture data sets available below 2.5 keV. The data available in EXFOR and in the literature have been used to perform a simple analysis above 2.5 keV. Conclusions: The results of this measurement contribute to reduce the Am243(n,γ) cross section uncertainty and suggest that this cross section is underestimated up to 25% in the neutron energy range between 50 eV and a few keV in the present evaluated data libraries.

Published
2014

197. Thyroid nodules classified as bethesda 3: final diagnosis

Author

Aura-Dulcinea Herrera-Martinez, Maria-Inmaculada Prior-Sanchez, Ana Barrera-Martin, Pedro Segui-Alpizcueta, Rodrigo Bahamondes-Opazo, Maria-Angeles Galvez-Moreno, Angel Rebollo-Roman, and Paloma Moreno-Moreno

Subjects
Thyroid nodules, Pathology, medicine.medical_specialty, business.industry, medicine, business, medicine.disease
Published
2016
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199. Presence and clinical-histological correlates of ghrelin and somatostatin systems components in gastroenteropancreatic neuroendocrine tumors and lung carcinoids

Author

Rafael Sánchez-Sánchez, Justo P. Castaño, Aura D. Herrera-Martinez, Raul M Luque, Maria Angeles Galvez Moreno, Juan Salvatierra, Rosa Ortega Salas, Manuel D. Gahete, and Raquel Serrano Blanch

Subjects
medicine.medical_specialty, Pathology, Endocrinology, Somatostatin, Lung, medicine.anatomical_structure, business.industry, Internal medicine, medicine, Ghrelin, Neuroendocrine tumors, business, medicine.disease
Published
2016
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200. Neutron-induced fission cross section ofNp237in the keV to MeV range at the CERN n_TOF facility

Author

L. Sarchiapone, S. Andriamonje, G. Cortes, J. Marganiec, R. C. Haight, P. E. Koehler, H. Álvarez, Masayuki Igashira, K. Ioannidis, M. Oshima, C. Lamboudis, J. L. Tain, C. Paradela, E. Chiaveri, P. F. Mastinu, A. Dorochenko, J. Andrzejewski, G. Aerts, J. Cox, A. J. M. Plompen, Isabel Lopes, B. Haas, Matthias Heil, J. Pancin, E. Skordis, L. Audouin, F. Voss, P. Cennini, S. David, Roberto Capote, P.A. Assimakopoulos, Thomas Rauscher, F. Neves, P. M. Milazzo, A. Tsinganis, Y. Kadi, G. Tagliente, I. Duran, H. Frais-Koelbl, Carlos Guerrero, U. Abbondanno, M. Mosconi, P. Pavlopoulos, D. Karadimos, Nicola Colonna, C. Rubbia, M. Kokkoris, Michael Wiescher, V. Konovalov, F. Bečvář, Heinz Oberhummer, S. O'Brien, E. González-Romero, Isabel S. Gonçalves, K. C. Stamoulis, S. Marrone, W. Dridi, I. Savvidis, J. Salgado, D. Cano-Ott, Marco Calviani, M. Diakaki, A. Poch, Vasilis Vlachoudis, A. Lindote, M. Sedysheva, R. Terlizzi, A. Goverdovski, M. Kerveno, Rene Reifarth, E. Griesmayer, V. Ketlerov, A. Plukis, F. Alvarez-Velarde, A. Carrillo de Albornoz, C. Papadopoulos, M. Embid-Segura, L. Ferrant, L. Tavora, K. Fuji, Gerald Badurek, F. Käppeler, Paraskevi Demetriou, L. Fitzpatrick, F. Gramegna, Ralf Plag, R. Dolfini, A. Pavlik, J. M. Quesada, C. Eleftheriadis, M. Rosetti, C. Pretel, Manuel Lozano, C. Domingo-Pardo, L. Tassan-Got, M. C. Vincente, D. Villamarin, P. Rullhusen, M. Krtička, F. Calviño, W.I. Furman, L. Perrot, Corrie S. Moreau, R. Ferreira-Marques, S. Lukic, V. Chepel, A. Herrera-Martinez, N. Patronis, G. Rudolf, L. Marques, P. Vaz, Arnaud Ferrari, Aaron Couture, P. Baumann, Alberto Mengoni, S. Isaev, A. Ventura, R. Vlastou, E. Berthoumieux, G. Vannini, R. Gallino, K. Wisshak, D. Karamanis, H. Wendler, D. Kolokolov, H. Leeb, C. Stephan, F. Gunsing, Cristian Massimi, and E. Jericha

Subjects
Physics, Large Hadron Collider, 010308 nuclear & particles physics, Fission, Model parameters, 7. Clean energy, 01 natural sciences, Nuclear physics, 0103 physical sciences, Homogeneity (physics), Ionization chamber, Neutron cross section, Neutron, Atomic physics, Nuclear Experiment, 010306 general physics, Spectroscopy
Abstract

The neutron-induced fission cross section of Np237 was experimentally determined at the high-resolution and high-intensity facility n-TOF, at CERN, in the energy range 100 keV to 9 MeV, using the U235(n,f) and U238(n,f) cross section standards below and above 2 MeV, respectively. A fast ionization chamber was used in order to detect the fission fragments from the reactions and the targets were characterized as far as their mass and homogeneity are concerned by means of α spectroscopy and Rutherford backscattering spectroscopy respectively. Theoretical calculations within the Hauser-Feshbach formalism have been performed, employing the empire code, and the model parameters were tuned in order to successfully reproduce the experimental fission cross-sectional data and simultaneously all the competing reaction channels.

Published
2016
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