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Young cattle and buffaloes were vaccinated subcutaneously and intradermally with a live vaccine containing Pasteurella multocida serotype B:3,4. Twelve months after vaccination three of five young cattle in the subcutaneously vaccinated group and three of four in the intradermally vaccinated group were protected against serotype B:2 challenge. Eleven buffaloes vaccinated subcutaneously and two vaccinated intradermally survived the same challenge 13 months after vaccination.

Disease prevalence in turkeys was estimated by totaling the flock size of necropsy cases submitted to the University of Georgia in 1986 for each disease reported and comparing it with the population at risk. Fowl cholera was the most prevalent disease in both commercial tom flocks (18.0%) and breeder hen flocks (14.7%). Prevalence of colibacillosis was 15.9% in commercial tom flocks, and prevalence of aspergillosis was 8.5% in commercial tom and 4.9% in breeder hen flocks.

Pasteurella multocida serotype B:3,4 isolated from a fallow deer in England was used as a vaccine to prevent haemorrhagic septicaemia. The deer strain was less virulent for calves than typical serotype B:2 of haemorrhagic septicaemia strains. It elicited antibodies in cattle that protected mice against serotype B:2 infection. The live deer vaccine containing 2 X 10(7) viable organisms per dose was used to immunise calves. Six months after vaccination, five of six calves were protected against serotype B:2 challenge. Two calves challenged nine months after vaccination survived the same challenge. The live vaccine was more efficacious than an alum precipitated vaccine in protecting calves against B:2 challenge.

Septicemic pasteurellosis caused by Pasteurella multocida is believed responsible for the deaths of 48 elk (Cervus elaphus) on the National Elk Refuge near Jackson, Wyoming (USA) during 1986 and 1987. Clinical signs included depression and salivation; necropsy findings included congestion and petechial and ecchymotic hemorrhages in lymph nodes, diaphragm, lungs and endocardium. Pasteurella multocida was isolated from femur marrow of eight carcasses and a variety of tissues from eight others.

ELISA and immunoblotting techniques were used to examine the humoral immune response to Pasteurella multocida, in bovine sera from Indonesia and Malaysia. Elevated levels of antibody to a crude lipopolysaccharide preparation were found in vaccinated animals. In addition to the response to lipopolysaccharide, antibodies from the vaccinated cattle strongly labelled five to six of the 40 protein bands in this organism.