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1,452 results on '"Hayward, S."'

159. Expedition report CCGS Hudson 2011036: Bay of Fundy

Author

Todd, B J, primary, Bossey, S E, additional, Boutilier, R R, additional, Brown, A O, additional, Bryk, J L, additional, Bugden, G L, additional, Currie, C G, additional, Hayward, S E, additional, Horne, E P, additional, Jarrett, C A, additional, LeBlanc, K W G, additional, Li, M Z, additional, Manning, DJ, additional, Mesling, P, additional, Murphy, RJ, additional, Neelands, P J, additional, Potter, D P, additional, Robertson, A G, additional, Spencer, PL, additional, and Standen, G B, additional

Published
2012
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174. Trace Elements in Head and Neck Cancer Patients: Zinc Status and Immunologic Functions

Author

Steven C. Marks, Hayward S. Penny, Ananda S. Prasad, Walter A. Salwen, Falah Shamsa, Frances W.J. Beck, Joseph Kaplan, and Robert H. Mathog

Subjects
medicine.medical_specialty, Univariate analysis, business.industry, Head and neck cancer, Cancer, chemistry.chemical_element, Zinc, medicine.disease, Gastroenterology, Peripheral blood mononuclear cell, Natural killer cell, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Immune system, Otorhinolaryngology, chemistry, 030220 oncology & carcinogenesis, Internal medicine, Immunology, medicine, Zinc deficiency, Surgery, 030223 otorhinolaryngology, business
Abstract

In this study we have assessed zinc status and zinc-dependent cell-mediated immune functions (interleukin-2 production by mononuclear cells, natural killer cell lytic activity, and interleukin-1β production by mononuclear cells) in adult patients with squamous cell carcinoma of the upper aerodigestive tract at diagnosis and before any therapy was instituted. Inasmuch as significant interactions between zinc, copper, and iron exist, we also assayed the plasma copper level, serum iron level, and total iron-binding capacity in our patients. We recruited 30 cancer subjects and 21 control subjects. On the basis of cellular zinc criteria, we diagnosed a mild deficiency of zinc in 53% of cancer subjects. The plasma zinc level was not decreased in our subjects. A univariate analysis was applied by use of one-way analysis of variance comparing study variables among the three study groups (controls and zinc-deficient and zinc-sufficient cancer patients) and Tukey's multiple comparison test, and we showed that interleukin-2 production and natural killer lytic activity were decreased in zinc-deficient cancer patients. Interleukin-1β production (ELISA assay) was increased in both zinc-deficient and zinc-sufficient groups. Plasma copper level was not different, but the iron utilization was decreased in both groups of cancer subjects. We conclude that zinc deficiency and zinc-dependent immunologic dysfunctions are present in more than half of the patients with head and neck cancer in the Detroit area.

Published
2018

176. Expedition report CCGS Hudson 2009 - 039: Bay of Fundy

Author

Todd, B J, primary, Brown, O, additional, Fromm, S A, additional, Hayward, S E, additional, Jerosch, K, additional, Kostylev, V E, additional, Li, M, additional, Manning, D, additional, Mesling, P, additional, Middleton, G, additional, Patton, E, additional, Pledge, PE, additional, Robertson, A, additional, Shaw, J, additional, Spencer, P L, additional, and Standen, G, additional

Published
2010
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182. Influence of A Thermogenic Dietary Supplement on Safety Markers, Body Composition, Energy Expenditure, Muscular Performance and Hormone Concentrations: A Randomized, Placebo-Controlled, Double-Blind Trial

Author

Grant Tinsley, Urbina, S., Mullins, J., Outlaw, J., Hayward, S., Stone, M., Foster, C., Wilborn, C., and Taylor, L.

Subjects
Research Article
Abstract

Dietary supplementation is commonly employed by individuals seeking to improve body composition and exercise performance. The purpose of the present study was to examine the safety and effectiveness of a commercially available dietary supplement designed to promote thermogenesis and fat loss. In a randomized double-blind trial, participants were assigned to consume placebo or a multi-ingredient supplement containing caffeine, green tea extract, l-carnitine, evodiamine and other ingredients that purportedly enhance thermogenesis. The study included acute baseline testing, a 6-week progressive resistance training and supplementation intervention, and post-intervention testing. Laboratory assessments included resting energy expenditure responses to acute supplement ingestion, evaluation of body composition and muscular performance, and analysis of blood variables (metabolic panel, testosterone, estrogen and cortisol). Dependent variables were analyzed using ANOVA with repeated measures. No unfavorable effects of supplementation were reported, and the supplement did not adversely affect safety markers. However, the supplement did not reduce fat mass or increase lean mass relative to placebo. In the supplement group, lower body maximal strength was increased relative to placebo (+18%, d=1.1 vs. +10%, d=0.5), and cortisol concentrations were decreased relative to placebo (-16%; d=-0.4 vs. +15%, d=.75). However, no differences were observed for upper body maximal strength or muscular endurance. REE increased in response to both supplement and placebo ingestion (placebo: +5%; supplement: +11.5%), but the difference between conditions was not statistically significant. Overall, some select parameters may have been beneficially modified by supplementation, but this did not result in superior weight or fat loss over 6 weeks of supplementation and resistance training.

Published
2017

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