Search

Your search keyword '"Guo, Zhigang"' showing total 1,630 results
Start Over Author "Guo, Zhigang"
1,630 results on '"Guo, Zhigang"'

167. Anthropocene 129I Record in the Yellow Sea Sediments and Its Indication for River-Delivered Radioactive Pollution to Marginal Seas

Author

Wang, Yanyun, Guo, Tianfeng, Fan, Yukun, Zhang, Luyuan, Guo, Zhigang, Cheng, Peng, Lan, Jianghu, Liu, Qi, and Hou, Xiaolin

Abstract

As the number of coastal nuclear facilities rapidly increases and the wastewater from the Fukushima Nuclear Plant has been discharged into the Pacific Ocean, the nuclear environmental safety of China’s marginal seas is gaining increased attention along with the heightened potential risk of nuclear accidents. However, insufficient work limits our understanding of the impact of human nuclear activities on the Yellow Sea (YS) and the assessment of their environmental process. This study first reports the 129I and 127I records of posthuman nuclear activities in the two YS sediments. Source identification of anthropogenic 129I reveals that, in addition to the gaseous 129I release and re-emission of oceanic 129I discharged from the European Nuclear Fuel Reprocessing Plants (NFRPs), the Chinese nuclear weapons testing fallout along with the global fallout is an additional 129I input for the continental shelf of the YS. The 129I/127I atomic ratios in the North YS (NYS) sediment are significantly higher than those in the other adjacent coastal areas, attributed to the significant riverine input of particulate 129I by the Yellow River. Furthermore, we found a remarkable 129I latitudinal disparity in the sediments than those in the seawaters in the various China seas, revealing that sediments in China’s marginal seas already received a huge anthropogenic 129I from terrigenous sources via rivers and thus became a significant sink of anthropogenic 129I. This study broadens an insight into the potential impacts of terrigenous anthropogenic pollution on the Chinese coastal marine radioactive ecosystem.

Published
2024
Full Text
View/download PDF

178. Trajectory Prediction in Campus Based on Markov Chains

Author

Wang, Bonan, Hu, Yihong, Shou, Guochu, Guo, Zhigang, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Weikum, Gerhard, Series editor, Wang, Yu, editor, Yu, Ge, editor, Zhang, Yanyong, editor, Han, Zhu, editor, and Wang, Guoren, editor

Published
2016
Full Text
View/download PDF

196. Effect of Wuling capsule on patients with generalized anxiety disorder

Author

Guo, Zhigang, Jia, An, Zhang, Tieshan, Li, Huixi, and Chen, Shan

Subjects
Generalized anxiety disorder, Wuling capsule, Anxiety, Depression
Abstract

Purpose: To investigate the effectiveness of Wuling capsule for the treatment of patients diagnosed with generalized anxiety disorder (GAD). Methods: Patients with generalized anxiety disorder (GAD) admitted in Affiliated Hospital of Huanghe Science and Technology College, Zhengzhou, China were treated with the Chinese traditional patent medicine, Wuling capsule. A self-control study was conducted before and after treatment. Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD), and Global Rating Scale (CGI-SI) were used to evaluate the symptoms of anxiety and depression suffered by GAD patients before and after treatment. Inflammatory factors (IL-6, IL-8, and IFN-γ), superoxide dismutase (SOD), γ-aminobutyric acid (GABA), and glutamic acid (Glu) levels were assessed in the peripheral blood of patients using ELISA before and after treatment. Results: A total of 58 patients with GAD completed 8 weeks of fixed-dose Wuling capsule treatment. After treatment, total scores on the HAMA scale, HAMD scale, and CGI scale significantly improved compared with baseline, and the differences before and after treatment were statistically significant (p < 0.01). The levels of inflammatory factors (IL-6, IL-8, and IFN-γ) in the peripheral blood of patients decreased significantly (p < 0.05). SOD and GABA/Glu increased after treatment (p < 0.05). Nine patients (15.5 %) had mild reactions, but no patients withdrew from the study as result of adverse reactions. Conclusion: The Chinese traditional patent medicine, Wuling capsule, is effective in the treatment of GAD patients with high safety. Future studies will need to explore the specific biological pathways and physiological processes that are involved in the treatment of GAD using Wuling capsule.&nbsp

Published
2023

199. A pomegranate seed-structured nanozyme-based colorimetric immunoassay for highly sensitive and specific biosensing of Staphylococcus aureus.

Author

Li, Jinghui, Tang, Yipeng, Bai, Yunpeng, Zhang, Zhejun, Zhang, Shaopeng, Chen, Tongyun, Zhao, Feng, and Guo, Zhigang

Subjects
PATHOGENIC bacteria, STAPHYLOCOCCUS aureus, POMEGRANATE, ENZYME-linked immunosorbent assay, COLORIMETRIC analysis, IMMUNOASSAY
Abstract

Staphylococcus aureus (S. aureus) infections are a serious threat to human health. The development of rapid and sensitive detection methods for pathogenic bacteria is crucial for accurate drug administration. In this research, by combining the advantages of enzyme-linked immunosorbent assay (ELISA), we synthesized nanozymes with high catalytic performance, namely pomegranate seed-structured bimetallic gold–platinum nanomaterials (Ps-PtAu NPs), which can catalyze a colorless TMB substrate into oxidized TMB (oxTMB) with blue color to achieve colorimetric analysis of S. aureus. Under the optimal conditions, the proposed biosensor could quantitatively detect S. aureus at levels ranging from 1.0 × 101 to 1.0 × 106 CFU mL−1 with a limit of detection (LOD) of 3.9 CFU mL−1. Then, an integrated color picker APP on a smartphone enables on-site point-of-care testing (POCT) of S. aureus with LOD as low as 1 CFU mL−1. Meanwhile, the proposed biosensor is successfully applied to the detection of S. aureus in clinical samples with high sensitivity and specificity. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

200. Targeting the mammalian target of rapamycin pathway in neurological manifestations of Covid‐19.

Author

Wang, Han, Cheng, Li, Yu, Lanlan, and Guo, Zhigang

Abstract

The diverse and severe nature of neurological manifestations associated with coronavirus disease 2019 (Covid‐19) has garnered increasing attention. Exploring the potential to decrease neurological complications in Covid‐19 patients involves targeting the mammalian target of rapamycin (mTOR) pathway as a therapeutic strategy. The mTOR pathway, widely recognised for its central role in essential cellular processes like synthesising proteins, facilitating autophagy, and modulating immune responses, has implications in various neurological disorders. Drawing parallels between these disorders and the observed neurological complications in Covid‐19, we present a comprehensive review on the current understanding of mTOR signalling in the context of severe acute respiratory syndrome coronavirus 2 infection and neuroinflammation. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results