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Your search keyword '"Grodsky, G M"' showing total 194 results
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194 results on '"Grodsky, G M"'

152. Insulin secretion in obesity: pseudodiabetes?

Author

Karam JH, Grodsky GM, and Forsham PH

Subjects
Age Factors, Animals, Diabetes Mellitus genetics, Glucagon, Glucose, Humans, Hyperplasia, Insulin blood, Insulin physiology, Insulin Resistance, Insulin Secretion, Islets of Langerhans, Diabetes Mellitus etiology, Insulin metabolism
Published
1968
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155. [Regulation of insulin release in perifused pancreatic tissue].

Author

Burr IM, Renold AE, Stauffacher W, Grodsky GM, and Balant L

Subjects
Amino Acids pharmacology, Animals, Aprotinin pharmacology, Arginine pharmacology, Freezing, Glucagon pharmacology, Glucose pharmacology, Hypoglycemic Agents pharmacology, In Vitro Techniques, Insulin Secretion, Islets of Langerhans enzymology, Leucine pharmacology, Pancreas drug effects, Perfusion, Rats, Sulfonamides pharmacology, Tolbutamide pharmacology, Insulin metabolism, Pancreas metabolism
Published
1969

158. [Further studies on the dynamic aspects of insulin release in vitro with evidence for a two-compartmental storage system].

Author

Grodsky GM, Curry D, Landahl H, and Bennett L

Subjects
Animals, Calcium pharmacology, Carbon Isotopes, Glucagon pharmacology, Glucose pharmacology, Hypoglycemic Agents pharmacology, In Vitro Techniques, Insulin Secretion, Models, Biological, Pancreas analysis, Pancreas drug effects, Perfusion, Protein Biosynthesis, Puromycin pharmacology, Rats, Sulfonamides pharmacology, Tolbutamide pharmacology, Valine metabolism, Insulin metabolism, Pancreas metabolism
Published
1969

160. Hyperinsulinuria in patients with renal calculi.

Author

Ching KN, Karam JH, Choy FB, Kolb FO, Grodsky GM, and Forsham PH

Subjects
Animals, Antibody Specificity, Blood Glucose analysis, Charcoal, Dextrans, Female, Guinea Pigs immunology, Humans, Immune Sera, Insulin blood, Iodine Isotopes, Kidney Calculi physiopathology, Kidney Tubules physiopathology, Male, Radioimmunoassay, Swine, Insulin urine, Kidney Calculi urine
Published
1972
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161. Comparison of insulin and 2-deoxy-D-glucose-induced glucopenia as stimulators of growth hormone secretion.

Author

Wegienka LC, Grodsky GM, Karam JH, Grasso SG, and Forsham PH

Subjects
Acromegaly metabolism, Addison Disease metabolism, Adolescent, Adult, Blood Glucose metabolism, Female, Growth Hormone blood, Humans, Hypoglycemia chemically induced, Hypopituitarism metabolism, Male, Middle Aged, Obesity metabolism, Pituitary Function Tests, Pituitary Gland physiology, Secretory Rate, Glucose biosynthesis, Glucose pharmacology, Growth Hormone biosynthesis, Insulin pharmacology
Published
1967
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162. The relationship of obesity and growth hormone to serum insulin levels.

Author

Karam JH, Grodsky GM, and Forsham PH

Subjects
Acromegaly physiopathology, Adolescent, Adult, Aged, Blood, Cushing Syndrome physiopathology, Dexamethasone pharmacology, Female, Hexoses pharmacology, Humans, Hyperglycemia physiopathology, In Vitro Techniques, Male, Middle Aged, Diabetes Mellitus, Growth Hormone, Insulin, Obesity
Published
1965
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167. Use of 2-deoxy-D-glucose in studying the mechanism of lipid mobilization.

Author

Grasso SG, Karam JH, Wegienka LC, Grodsky GM, and Forsham PH

Subjects
Adenoma, Chromophobe complications, Adult, Blood Glucose, Clinical Trials as Topic, Epinephrine urine, Fatty Acids, Nonesterified blood, Growth Hormone blood, Humans, Middle Aged, Radioimmunoassay, Acromegaly metabolism, Addison Disease metabolism, Cushing Syndrome metabolism, Epinephrine physiology, Fatty Acids, Nonesterified metabolism, Growth Hormone physiology, Hexoses pharmacology, Hypopituitarism metabolism, Lipid Metabolism, Obesity metabolism
Published
1968
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172. Effect of age of rat on development of hepatic carriers for bilirubin: a possible explanation for physiologic jaundice and hyperbilirubinemia in the newborn.

Author

Grodsky GM, Kolb HJ, Fanska RE, and Nemechek C

Subjects
Animals, Chromatography, Gel, Humans, Hydrogen-Ion Concentration, Infant, Newborn, Rats, Age Factors, Bilirubin metabolism, Hyperbilirubinemia, Hereditary, Jaundice, Neonatal etiology, Liver metabolism, Protein Binding, Proteins metabolism, Sulfobromophthalein metabolism
Published
1970
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173. Dynamics of insulin secretion by the perfused rat pancreas.

Author

Curry DL, Bennett LL, and Grodsky GM

Subjects
Animals, Calcium pharmacology, Carbon Isotopes, Depression, Chemical, In Vitro Techniques, Insulin Secretion, Islets of Langerhans anatomy & histology, Islets of Langerhans drug effects, Male, Oxygen Consumption, Perfusion, Portal Vein, Protein Biosynthesis, Puromycin pharmacology, Rats, Tolbutamide pharmacology, Valine metabolism, Insulin metabolism, Islets of Langerhans metabolism
Published
1968
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176. Glucose tolerance and insulin response of potassium-deficienct rat and isolated liver.

Author

Mondon CE, Burton SD, Grodsky GM, and Ishida T

Subjects
Amino Acids analysis, Animals, Body Weight, Corticosterone blood, Glucose pharmacology, Glucose Tolerance Test, Injections, Intravenous, Injections, Subcutaneous, Insulin pharmacology, Lactates analysis, Male, Muscles analysis, Nitrogen analysis, Potassium blood, Rats, Sodium blood, Urea analysis, Blood Glucose analysis, Glucose metabolism, Insulin blood, Liver analysis, Potassium pharmacology, Potassium Deficiency metabolism
Published
1968
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177. Acromegaly. The effects of various steroid hormones on the insulin-induced growth hormone response.

Author

Deller JJ Jr, Di Raimondo VC, Grodsky GM, and Forsham PH

Subjects
Acromegaly diagnosis, Humans, Acromegaly drug therapy, Growth Hormone, Hormones therapeutic use, Insulin pharmacology
Abstract

The availability of a sensitive assay for human growth hormone has made it possible to directly measure the effects of various agents purported to alter growth patterns. Acromegalic patients present a special problem both in early diagnosis and in therapy. Being able to measure growth hormone in these patients provides an accurate index of activity and a precise measure of therapeutic effectiveness. In an attempt to determine whether a pituitary block of growth hormone secretion is feasible in this condition, a study was made of the effects of estrogen, androgen and glucocorticoid administration on growth hormone response to a standard insulin tolerance test in a patient with active acromegaly. In the dosage schedules used in this study, it was not possible to suppress either basal growth hormone secretion or blunt its responsiveness to the normal physiologic stimulus of hypoglycemia.

Published
1966

178. Insulin and the pancreas.

Author

Grodsky GM and Forsham PH

Subjects
Animals, Humans, In Vitro Techniques, Insulin Antibodies, Insulin, Islets of Langerhans metabolism
Published
1966
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179. Biological and immunological activity of fructose 1,6-diphosphatase. Application of a quantitative displacement radioimmunoassay.

Author

Kolb HJ and Grodsky GM

Subjects
Adenine Nucleotides, Animals, Biological Assay, Brain immunology, Cattle, Chemical Precipitation, Chloramines, Cross Reactions, Fructose, Fructose-Bisphosphatase antagonists & inhibitors, Fructose-Bisphosphatase isolation & purification, Guinea Pigs, Horses, Immune Sera, Immunodiffusion, Immunoelectrophoresis, Iodine Isotopes, Kidney enzymology, Liver enzymology, Methods, Muscles immunology, Myocardium immunology, Rabbits, Rats, Sheep, Sodium, Spectrophotometry, Sulfates, Swine, Fructose-Bisphosphatase analysis, Radioimmunoassay
Published
1970
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182. Insulin and the pancreas.

Author

Grodsky GM

Subjects
Amino Acid Sequence, Animals, Cattle, Central Nervous System drug effects, Chemical Phenomena, Chemistry, Drug Synergism, Feedback, Gluconeogenesis, Glycogen biosynthesis, Glycolysis, Hormones pharmacology, Insulin Secretion, Islets of Langerhans metabolism, Lipids pharmacology, Nucleotides pharmacology, Proinsulin metabolism, Protein Conformation, Rats, Structure-Activity Relationship, Sulfonylurea Compounds pharmacology, Insulin biosynthesis, Insulin chemical synthesis, Insulin metabolism, Pancreas drug effects
Published
1970
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184. Evaluation of the role of exogenous insulin on phasic insulin secretion.

Author

Grodsky GM, Fanska R, and Schmid FG

Subjects
Animals, Culture Techniques, Feedback, Glucose pharmacology, Insulin pharmacology, Insulin Secretion, Islets of Langerhans drug effects, Radioimmunoassay, Rats, Stimulation, Chemical, Time Factors, Tolbutamide pharmacology, Insulin metabolism, Islets of Langerhans metabolism
Published
1973
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186. Adenosine 3',5'-monophosphate in pancreatic islets: glucose-induced insulin release.

Author

Charles MA, Fanska R, Schmid FG, Forsham PH, and Grodsky GM

Subjects
Animals, Cyclic AMP physiology, Insulin Secretion, Islets of Langerhans drug effects, Male, Rats, Theophylline pharmacology, Cyclic AMP metabolism, Glucose pharmacology, Insulin metabolism, Islets of Langerhans metabolism
Abstract

Glucose-induced release of insulin from perifused rat islets is associated with elevated islet adenosine 3',5'-monophosphate. If values for adenosine 3',5'-monophosphate are compared to insulin release during theophylline or glucose stimulation and theophylline plus glucose stimulation, it suggests a minor role for adenosine 3',5'-monophosphate in directly stimulating insulin release but a prominent role in modulating glucose-induced release of insulin.

Published
1973
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189. Relationships between arginine and glucose in the induction of insulin secretion from the isolated, perfused rat pancreas.

Author

Levin SR, Grodsky GM, Hagura R, Smith DF, and Forsham PH

Subjects
Animals, Arginine administration & dosage, Drug Synergism, Glucose administration & dosage, In Vitro Techniques, Insulin Secretion, Pancreas drug effects, Perfusion, Rats, Stimulation, Chemical, Time Factors, Arginine pharmacology, Drug Interactions, Glucose pharmacology, Insulin metabolism, Pancreas metabolism
Published
1972
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190. The histopathology of immune diabetes in the rabbit.

Author

Toreson WE, Lee JC, and Grodsky GM

Subjects
Adjuvants, Immunologic pharmacology, Animals, Blood Glucose analysis, Cell Aggregation, Diabetes Mellitus immunology, Hyperglycemia etiology, Insulin Antibodies analysis, Leukocytes, Lymphocytes, Microscopy, Electron, Monocytes, Pancreas pathology, Rabbits, Diabetes Mellitus pathology, Islets of Langerhans pathology
Published
1968

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