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191 results on '"Grigoryev, Dmitry"'

156. Transcriptional analysis of infiltrating T cells in kidney ischemia-reperfusion injury reveals a pathophysiological role for CCR5.

Author

Gang Jee Ko, Linfert, Douglas, Hye Ryoun Jang, Higbee, Elizabeth, Watkins, Tonya, Cheadle, Chris, Manchang Liu, Racusen, Lorraine, Grigoryev, Dmitry N., and Rabb, Hamid

Abstract

Although T cells have been shown to play a direct role in kidney ischemia-reperfusion injury (IRI), little is known about the underlying mechanisms. We hypothesized that studying the transcriptional responses in kidney-infiltrating T cells would help elucidate novel therapeutic targets for kidney IRI. Unilateral renal pedicle clamping for 45 min was performed in male C57BL/6 mice, and CD3+ T cells were isolated from the kidney and purified. Transcriptional activities of T cell were measured by array-based PCR compared between ischemic kidneys and contralateral nonischemic kidneys. Among total of 89 genes analyzed, 24, 22, 24, and 37 genes were significantly changed at 6 h, day 3, day 10, and day 28 after IRI. Genes associated with cytokines, chemokines, and costimulatory molecules were upregulated. Pathway analysis identified CC motif chemokine receptor 5 (CCR5) as a candidate pathophysiological pathway. CCR5 upregulation was validated at the protein level, and CCR5 blockade improved renal function after kidney IRI. Using discovery techniques to identify transcriptional responses in purified kidney-infiltrating cells enabled the elucidation of novel mechanisms and therapeutic targets for IRI. [ABSTRACT FROM AUTHOR]

Published
2012
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157. Transcriptional analysis of kidneys during repair from AKI reveals possible roles for NGAL and KIM-1 as biomarkers of AKI-to-CKD transition.

Author

Gang Jee Ko, Grigoryev, Dmitry N., Linfert, Douglas, Hye Ryoun Jang, Watkins, Tonya, Cheadle, Chris, Racusen, Lorraine, and Rabb, Hamid

Subjects
*CHRONIC kidney failure, *REPERFUSION injury, *DNA fingerprinting, *BIOMARKERS, *LABORATORY mice, *GENETICS
Abstract

Acute kidney injury (AKI) is being increasingly shown to be a risk factor for chronic kidney disease (CKD), but little is known about the possible mechanistic links. We hypothesized that analysis of the genomic signature in the repair stage after AKI would reveal pathways that could link AKI and CKD. Unilateral renal pedicle clamping for 45 min was performed in male C57BL/6J mice. Mice were euthanized at 3, 10, and 28 days after ischemia-reperfusion injury (IRI). Total RNA was isolated from kidney and analyzed using an Illumina mouse array, Among 24,600 tested genes, 242, 146, and 46 genes were upregulated at days 3, 10, and 28 after IRI, and 85, 35, and 0 genes were downregulated respectively. Gene ontology analysis showed that gene expression changes were primarily related to immune and inflammatory pathways both early and late after AKI. The most highly upregulated genes late after AKI were hepatitis A virus cellular receptor 1 (Havcr1) and lipocalin 2 (Lcn2), which code for kidney injury molecule-1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL), respectively. This was unexpected since they are both primarily potential biomarkers of the early stage of AKI. Furthermore, increases observed in gene expression in amiloride binding protein 1, vascular cell adhesion molecule-1, and endothelin 1 could explain the salt-sensitive hypertension that can follow AKI. These data suggested that 1) persistent inflammation and immune responses late after AKI could contribute to the pathogenesis of CKD, 2) late upregulation of KIM-1 and NGAL could be a useful marker for sustained renal injury after AKI, and 3) hypertension-related gene changes could underlie mechanisms for persistent renal and vascular injury after AKI. [ABSTRACT FROM AUTHOR]

Published
2010
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158. TNF-α increase tyrosine phosphorylation of vascular endothelial cadherin and opens the paracellular pathway through fyn activation in human lung endothelia.

Author

Angellini, Daniel J., Sang-Won Hyun, Grigoryev, Dmitry N., Garg, Pallavi, Ping Gong, Singh, Ishwar S., Passaniti, Antonio, Hasday, Jeffery D., and Goldblum, Simeon E.

Subjects
TUMOR necrosis factors, SEPSIS, TYROSINE, AMINO acids, OSMOSIS, PHOSPHORYLATION
Abstract

Tumor necrosis factor (TNF)-α is a key mediator of sepsis-associated multiorgan failure, including the acute respiratory distress syndrome. We examined the role of protein tyrosine phosphorylation in TNF-α- induced pulmonary vascular permeability. Postconfluent human lung microvascular and pulmonary artery endothelial cell (EC) monolayers exposed to human recombinant TNF-α displayed a dose- and time-dependent increase in transendothelial [14C]albumin flux in the absence of EC injury. TNF-α also increased tyrosine phosphorylation of EC proteins, and several substrates were identified as the zonula adherens proteins vascular endothelial (VE)-cadherin, and β-catenin, γ-catenin, and p120 catenin (p120ctn). Prior protein tyrosine kinase (PTK) inhibition protected against the TNF-α effect. TNF-α activated multiple PTKs, including src family PTKs. Prior PTK inhibition with the src-selective agents PP1 and PP2 each protected against ~60% of the TNF-α-induced increment in [14C]albumin flux. PP2 also blocked TNF-α-induced tyrosine phosphorylation of VE-cadherin, γ-catenin, and p120ctn. To identify which src family kinase(s) was required for TNF-α-induced vascular permeability, small interfering RNA (siRNA) targeting each of the three src family PTKs expressed in human EC, c-src, fyn, and yes, were introduced into the barrier function assay. Only fyn siRNA protected against the TNF-α effect, whereas the c-src and yes siRNAs did not. These combined data suggest that TNF-α regulates the pulmonary vascular endothelial paracellular pathway, in part, through fyn activation. [ABSTRACT FROM AUTHOR]

Published
2006
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159. Chronic intermittent hypoxia upregulates genes of lipid biosynthesis in obese mice.

Author

Jianguo Li, Grigoryev, Dmitry N., Shul Qing Ye, Thorne, Laura, Schwartz, Alan R., Smith, Philip L., O'Donnell, Christopher P., and Polotsky, Vsevolod Y.

Subjects
HYPOXEMIA, GENETIC regulation, LIPIDS, BIOSYNTHESIS, OBESITY
Abstract

Obstructive sleep apnea (OSA), a condition tightly linked to obesity, leads to chronic intermittent hypoxia (CIH) during sleep. There is emerging evidence that OSA is independently associated with insulin resistance and fatty liver disease, suggesting that OSA may affect hepatic lipid metabolism. To test this hypothesis, leptin-deficient obese (ob/ob) mice were exposed to CIH during the light phase (9 AM-9 PM) for 12 wk. Liver lipid content and gene expression profile in the liver (Affymetrix 430 GeneChip with real-time PCR validation) were determined on completion of the exposure. CIH caused a 30% increase in triglyceride and phospholipid liver content (P < 0.05), whereas liver cholesterol content was unchanged. Gene expression analysis showed that CIH upregulated multiple genes controlling 1) cholesterol and fatty acid biosynthesis [malic enzyme and acetyl coenzyme A (CoA) synthetase], 2) predominantly fatty acid biosynthesis (acetyl-CoA carboxylase and stearoyl-CoA desaturases 1 and 2), and 3) triglyceride and phospholipid biosynthesis (mitochondrial glycerol-3-phosphate acyltransferase). A majority of overexpressed genes were transcriptionally regulated by sterol regulatory element-binding protein (SREBP) 1, a master regulator of lipogenesis. A 2.8-fold increase in SREBP-1 gene expression in CIH was confirmed by real-time PCR (P = 0.001). Expression of major genes of cholesterol biosynthesis, SREBP-2 and 3-hydroxy-3-methylglutaryl-CoA reductase, was unchanged. In conclusion, we have shown that CIH may exacerbate preexisting fatty liver of obesity via upregulation of the pathways of lipid biosynthesis in the liver. [ABSTRACT FROM AUTHOR]

Published
2005
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160. Bioinformatic identification of novel early stress response genes in rodent models of lung injury.

Author

Shwu-Fan Ma, Grigoryev, Dmitry N., Taylor, Angela D., Nonas, Stephanie, Sammani, Saad, Shui Qing Ye, and Garcia, Joe G. N.

Subjects
*LUNG injuries, *LABORATORY rodents, *ARTIFICIAL respiration, *BIOINFORMATICS, *GENE expression
Abstract

Acute lung injury is a complex illness with a high mortality rate (>30%) and often requires the use of mechanical ventilatory support for respiratory failure. Mechanical ventilation can lead to clinical deterioration due to augmented lung injury in certain patients, suggesting the potential existence of genetic susceptibility to mechanical stretch (6, 48), the nature of which remains unclear. To identify genes affected by ventilator-induced lung injury (VILI), we utilized a bioinformatic-intense candidate gene approach and examined gene expression profiles from rodent VILI models (mouse and rat) using the oligonucleotide microarray platform. To increase statistical power of gene expression analysis, 2,769 mouse/rat orthologous genes identified on RG̱U34A and MG̱U74Av2 arrays were simultaneously analyzed by significance analysis of microarrays (SAM). This combined ortholog/SAM approach identified 41 up- and 7 downregulated VILI-related candidate genes, results validated by comparable expression levels obtained by either real-time or relative RT-PCR for 15 randomly selected genes. K-mean clustering of 48 VILI-related genes clustered several well-known VILI-associated genes (IL-6, plasminogen activator inhibitor type 1, CCL-2, cyclooxygenase-2) with a number of stress-related genes (Myc, Cyr61, Socs3). The only unannotated member of this cluster (n = 14) was RIKEṈ1300002F13 EST, an ortholog of the stress-related Gene33/Mig-6 gene. The further evaluation of this candidate strongly suggested its involvement in development of VILI. We speculate that the ortholog-SAM approach is a useful, time- and resource-efficient tool for identification of candidate genes in a variety of complex disease models such as VILI. [ABSTRACT FROM AUTHOR]

Published
2005
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161. Paranormal beliefs and core knowledge confusions: A meta-analysis.

Author

Gallyamova, Albina, Komyaginskaya, Elizaveta, and Grigoryev, Dmitry

Subjects
*MENTALIZATION, *HETEROGENEITY, *INFORMATION processing, *CLASSIFICATION, *METAPHOR
Abstract

This meta-analysis examines the relationship between paranormal beliefs and Core Knowledge Confusions (CKC), a concept introduced by Lindeman and Aarnio (2007) to explore the link between ontological errors and belief in the paranormal. The CKC, which uses metaphor classification to assess ontological confusion, suggests that cognitive processes organize information into ontologies, and our interpretation of literal versus metaphorical expressions reflects these categorizations. Despite advancements in education, ontological confusion persists, manifesting in various forms like mentalization of matter, physicalization of the mental, and biologization of the mental. Our analysis, encompassing 25 effect sizes with 16,129 participants from 11 countries and publications over 14 years, found a significant average effect size (r = 0.40) in the relationship between paranormal beliefs and the CKC, indicating a robust and consistent association across various populations and contexts. The study observed that contextual factors specific to data from Finland enhance the estimated magnitude of the effect size. Despite considerable heterogeneity and potential influences of unexamined moderators, the results suggest a universal cognitive pattern linking paranormal beliefs with certain types of ontological confusion. This meta-analysis underscores the need for further exploration into contextual variations in understanding the complex relationship between paranormal beliefs and ontological errors. • Meta-analysis shows robust, consistent correlations. • Paranormal beliefs linked to core knowledge confusions, r = 0.40. • Finnish data crucially shifts effect size. • Urges cross-cultural research and precise measures. [ABSTRACT FROM AUTHOR]

Published
2024
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162. Science review: Searching for gene candidates in acute lung injury

Author

Grigoryev, Dmitry, Finigan, James, Hassoun, Paul, and Garcia, Joe

Abstract

Acute lung injury (ALI) is a complex and devastating illness, often occurring within the setting of sepsis, and carries an annual mortality rate of 30–50%. Although the genetic basis of ALI has not been fully established, an increasing body of evidence suggests that genetic predisposition contributes to disease susceptibility and severity. Significant difficulty exists, however, in defining the exact nature of these genetic factors, including large phenotypic variance, incomplete penetrance, complex gene–environment interactions, and strong potential for locus heterogeneity. We utilized the candidate gene approach and an ortholog gene database to provide relevant gene ontologies and insights into the genetic basis of ALI. We employed a Medline search of selected basic and clinical studies in the English literature and studies sponsored by the HopGene National Institutes of Health sponsored Program in Genomic Applications. Extensive gene expression profiling studies in animal models of ALI (rat, murine, canine), as well as in humans, were performed to identify potential candidate genes http://www.hopkins-genomics.org/. We identified a number of candidate genes for ALI, with blood coagulation and inflammation gene ontologies being the most highly represented. The candidate gene approach coupled with extensive gene profiling and novel bioinformatics approaches is a valuable way to identify genes that are involved in ALI.

Published
2004
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163. Network psychometric-based identification and structural analysis of a set of evolved human motives.

Author

Aunger, Robert, Gallyamova, Albina, and Grigoryev, Dmitry

Abstract

Establishing a limited set of motives characteristic of the human species has been a goal in psychology since the beginning of the discipline. This paper uses a network-based analysis of previously published psychometric data to establish the existence of a pre-defined set of human motives. The set was derived by using evolutionary theory to identify what sorts of goals humans need to achieve to survive and reproduce in the niche our species evolved to fill. The analysis reported here is based on responses obtained from an on-line sample of 510 representative residents of the United Kingdom to 150 items. Analysis shows that all fifteen of the identified motives can be isolated, that they show expected relationships to one another (based on common functionality), and that differences in attentiveness to motives by gender reflect traditional gender-based role-play during human evolution, while differences by age are consistent with expectations from life history theory. The reduced set of 45 items identified by a genetic algorithm-based analysis could form the basis of a psychometric scale. Knowing the set of motives behind goal-directed behaviour should prove a significant boon to a wide variety of psychological applications, including human relations, educational strategies, marketing and behaviour change. • 15 theory-derived motives are identified by network-based psychometric analysis. • Motives cluster into categories related to their function in life. • Some motives assume additional importance during expected life-historical periods. • Some motives are more important in the lives of one gender than the other. [ABSTRACT FROM AUTHOR]

Published
2025
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164. In COVID-19 health messaging, loss framing increases anxiety with little-to-no concomitant benefits: experimental evidence from 84 countries

Author

Dorison, Charles A., Lerner, Jennifer S., Heller, Blake H., Rothman, Alexander J., Kawachi, Ichiro I., Wang, Ke, Rees, Vaughan W., Gill, Brian P., Gibbs, Nancy, Ebersole, Charles R., Vally, Zahir, Tajchman, Zuzanna, Zsido, Andras N., Zrimsek, Mija, Chen, Zhang, Ziano, Ignazio, Gialitaki, Zoi, Ceary, Chris D., Lin, Yijun, Kunisato, Yoshihiko, Yamada, Yuki, Xiao, Qinyu, Jiang, Xiaoming, Du, Xinkai, Yao, Elvin, Wilson, John Paul, Cyrus-lai, Wilson, Jimenez-leal, William, Law, Wilbert, Collins, W. Matthew, Richard, Karley L., Vranka, Marek, Ankushev, Vladislav, Schei, Vidar, Križanić, Valerija, Kadreva, Veselina Hristova, Adoric, Vera Cubela, Tran, Ulrich S., Yeung, Siu Kit, Hassan, Widad, Houston, Ralph, Lima, Tiago J. S., Ostermann, Thomas, Frizzo, Thomas, Sverdrup, Therese E., House, Thea, Gill, Tripat, Fedotov, Maksim, Paltrow, Tamar, Jernsäther, Teodor, Koptjevskaja-tamm, Maria, Hostler, Thomas J., Ishii, Tatsunori, Szaszi, Barnabas, Adamus, Sylwia, Suter, Lilian, Habib, Sumaiya, Studzinska, Anna, Stojanovska, Dragana, Janssen, Steve M. J., Stieger, Stefan, Schulenberg, Stefan E., Tatachari, Srinivasan, Azouaghe, Soufian, Sorokowski, Piotr, Sorokowska, Agnieszka, Song, Xin, Lewis, Savannah C., Sinkolova, Sladjana, Grigoryev, Dmitry, Drexler, Shira Meir, Daches, Shimrit, Geniole, Shawn N., Vračar, Selena, Massoni, Sébastien, Zorjan, Saša, Sarıoğuz, Eylül, Izquierdo, Sara Morales, Alves, Sara G., Pöntinen, Sara, Solas, Sara Álvarez, Ordoñez-riaño, Santiago, Očovaj, Sanja Batić, Onie, Sandersan, Lins, Samuel, Çoksan, Sami, Sacakli, Asli, Ruiz-fernández, Susana, Geiger, Sandra J., Fatahmodares, Saeideh, Walczak, Radoslaw B., Betlehem, Ruben, Vilar, Roosevelt, Cárcamo, Rodrigo, Ross, Robert M., Mccarthy, Randy, Ballantyne, Tonia, Westgate, Erin C., Afhami, Reza, Ren, Dongning, Monteiro, Renan P., Reips, Ulf-dietrich, Reggev, Niv, Calin-jageman, Robert J., Pourafshari, Razieh, Oliveira, Raquel, Nedelcheva-datsova, Mina, Rahal, Rima-maria, Ribeiro, Rafael R., Radtke, Theda, Searston, Rachel, Habte, Redeate, Zdybek, Przemysław, Chen, Sau-chin, Maturan, Princess Lovella G., Perillo, Jennifer T., Isager, Peder Mortvedt, Kačmár, Pavol, Macapagal, Paulo Manuel, Szwed, Paulina, Hanel, Paul H. P., Forbes, Paul A. G., Arriaga, Patrícia, Paris, Bastien, Papachristopoulos, Konstantinos, Correa, Pablo Sebastián, Kácha, Ondřej, Bernardo, Márcia, Campos, Olatz, Bravo, Olalla Niño, Galindo-caballero, Oscar J., Ogbonnaya, Chisom Esther, Bialobrzeska, Olga, Kiselnikova, Natalia, Simonovic, Nicolle, Cohen, Noga, Nock, Nora L., Johannes, Niklas, Albayrak-aydemir, Nihan, Say, Nicolas, Torunsky, Nathan, Van Doren, Natalia, Sunami, Naoyuki, Rachev, Nikolay R., Majeed, Nadyanna M., Schmidt, Nadya-daniela, Nadif, Khaoula, Corral-frías, Nadia S., Ouherrou, Nihal, Pantazi, Myrto, Lucas, Marc Y., Vasilev, Martin R., Ortiz, María Victoria, Butt, Muhammad Mussaffa, Kabir, Muhib, Muda, Rafał, Tejada Rivera, Maria Del Carmen Mc, Sirota, Miroslav, Seehuus, Martin, Parzuchowski, Michal, Toro, Mónica, Hricova, Monika, Maldonado, Mónica Alarcón, Marszalek, Magdalena, Karekla, Maria, Mioni, Giovanna, Bosma, Minke Jasmijn, Westerlund, Minja, Vdovic, Milica, Bialek, Michal, Silan, Miguel A., Anne, Michele, Misiak, Michal, Grinberg, Maurice, Capizzi, Mariagrazia, Espinoza Barría, Mauricio F., Kurfali, Merve A., Mensink, Michael C., Harutyunyan, Mikayel, Khosla, Meetu, Korbmacher, Max, Adamkovič, Matúš, Ribeiro, Matheus Fernando Felix, Terskova, Maria, Hruška, Matej, Martončik, Marcel, Voracek, Martin, Čadek, Martin, Frías-armenta, Martha, Kowal, Marta, Topor, Marta, Roczniewska, Marta, Oosterlinck, Marlies, Kohlová, Markéta Braun, Paruzel-czachura, Mariola, Romanova, Marina, Papadatou-pastou, Marietta, Lund, Maria Louise, Antoniadi, Maria, Jones, Marc V., Ortiz, Manuel S., Manavalan, Mathi, Muminov, Abdumalik, Kossowska, Małgorzata, Friedemann, Maja, Wielgus, Magdalena, Varella, Marco A. C., Colloff, Melissa F., Bradford, Maria, Vaughn, Leigh Ann, Eudave, Luis, Vieira, Luc, Pineda, Lina Maria Sanabria, Pérez, Laura Calderón, Lazarevic, Ljiljana B., Jaremka, Lisa M., Kushnir, Elizaveta, Anton-boicuk, Lisa, De Holanda Coelho, Gabriel Lins, Ahlgren, Lina, Levitan, Carmel A., Micheli, Leticia, Volz, Leonhard, Stojanovska, Marija, Boucher, Leanne, Samojlenko, Lara, Delgado, Lady Grey Javela, Kaliska, Lada, Warmelink, Lara, Rojas-berscia, Luis Miguel, Yu, Karen, Wachowicz, Jakub, Desai, Kermeka, Barzykowski, Krystian, Kozma, Luca, Evans, Kortnee, Kirgizova, Komila, Agesin, Bamikole Emmanuel, Koehn, Monica A, Wolfe, Kelly, Korobova, Tatiana, Klevjer, Kristoffer, Van Schie, Kevin, Vezirian, Kevin, Damnjanović, Kaja, Thommesen, Katrine Krabbe, Schmidt, Kathleen, Filip, Katarzyna, Grzech, Karolina, Hoyer, Karlijn, Moon, Karis, Rana, Kafeel, Janjić, Kristina, Suchow, Jordan W., Kielińska, Julita, Cruz Vásquez, Julio E, Beitner, Julia, Vargas-nieto, Juan Camilo, Roxas, Jose Carlos T., Taber, Jennifer, Urriago-rayo, Joan, Pavlacic, Jeffrey M., Bavolar, Jozef, Soto, José A., Olofsson, Jonas K., Vilsmeier, Johannes K., Messerschmidt, Johanna, Czamanski-cohen, Johanna, Boudesseul, Jordane, Lee, Jeong Min, Kamburidis, Julia, Zickfeld, Janis, Miranda, Jacob F., Verharen, Jeroen P. H., Hristova, Evgeniya, Beshears, Julie E., Đorđević, Jasna Milošević, Bosch, Jasmijn, Valentova, Jaroslava Varella, Antfolk, Jan, Berkessel, Jana B., Schrötter, Jana, Urban, Jan, Röer, Jan Philipp, Norton, James O, Silva, Jaime R., Pickering, Jade S., Vintr, Jáchym, Uttley, Jim, Kunst, Jonas R., Ndukaihe, Izuchukwu L. G., Iyer, Aishwarya, Vilares, Iris, Ivanov, Aleksandr, Ropovik, Ivan, Sula, Isabela, Sarieva, Irena, Metin-orta, Irem, Prusova, Irina, Pinto, Isabel, Bozdoc, Andreea Ioana, Almeida, Inês A. T., Pit, Ilse L., Dalgar, Ilker, Zakharov, Ilya, Arinze, Azuka Ikechukwu, Ihaya, Keiko, Stephen, Ian D., Gjoneska, Biljana, Brohmer, Hilmar, Flowe, Heather, Godbersen, Hendrik, Kocalar, Halil Emre, Hedgebeth, Mattie V., Chuan-peng, Hu, Sharifian, Mohammadhasan, Manley, Harry, Akkas, Handan, Hajdu, Nandor, Azab, Habiba, Kaminski, Gwenael, Nilsonne, Gustav, Anjum, Gulnaz, Travaglino, Giovanni A., Feldman, Gilad, Pfuhl, Gerit, Czarnek, Gabriela, Marcu, Gabriela Mariana, Hofer, Gabriela, Banik, Gabriel, Adetula, Gabriel Agboola, Bijlstra, Gijsbert, Verbruggen, Frederick, Kung, Franki Y. H., Foroni, Francesco, Singer, Gage, Muchembled, Fany, Azevedo, Flavio, Mosannenzadeh, Farnaz, Marinov, Evelina, Štrukelj, Eva, Etebari, Zahra, Baskin, Ernest, Garcia, Elkin Oswaldo Luis, Musser, Erica, Van Steenkiste, I.m.m., Ahn, El Rim, Pronizius, Ekaterina, Jackson, Emily A, Manunta, Efisio, Agadullina, Elena, Šakan, Dušana, Dursun, Pinar, Dujols, Olivier, Dubrov, Dmitrii, Willis, Megan, Tümer, Murat, Beaudry, Jennifer L., Popović, Dora, Dunleavy, Daniel, Djamai, Ikhlas, Krupić, Dino, Vega, Diego, Du, Hongfei, Mola, Débora, Davis, William E., Holford, Dawn Liu, Lewis, David M. G., Vaidis, David C., Ozery, Daphna Hausman, Ricaurte, Danilo Zambrano, Storage, Daniel, Sousa, Daniela, Alvarez, Daniela Serrato, Rosa, Anna Dalla, Krupić, Dajana, Marko, Dafne, Moreau, David, Reeck, Crystal, Correia, Rita C., Whitt, Cassie M., Lamm, Claus, Solorzano, Claudio Singh, Von Bastian, Claudia C., Sutherland, Clare Am, Overkott, Clara, Aberson, Christopher L., Wang, Chunhui, Karashiali, Christiana, Noone, Chris, Chiu, Faith, Picciocchi, Chiara, Karaarslan, Cemre, Cellini, Nicola, Esteban-serna, Celia, Reyna, Cecilia, Batres, Carlota, Li, Ranran, Grano, Caterina, Carpentier, Joelle, Tamnes, Christian K., Fu, Cynthia H.y., Ishkhanyan, Byurakn, Bylinina, Lisa, Jaeger, Bastian, Bundt, Carsten, Allred, Tara Bulut, Bokkour, Ahmed, Bogatyreva, Natalia, Chopik, William J., Antazo, Benedict, Behzadnia, Behzad, Becker, Maja, Cocco, Beatrice, Chou, Wei-lun, Hubena, Barbora, Žuro, Barbara, Aczel, Balazs, Baklanova, Ekaterina, Bai, Hui, Balci, Busra Bahar, Babinčák, Peter, Dixson, Barnaby James Wyld, Mokady, Aviv, Kappes, Heather Barry, Atari, Mohammad, Szala, Anna, Szabelska, Anna, Aruta, John Jamir Benzon, Domurat, Artur, Arinze, Nwadiogo Chisom, Modena, Arianna, Adiguzel, Arca, Monajem, Arash, Arabi, Kanza Ait El, Özdoğru, Asil Ali, Olaya Torres, Adriana Julieth, Theodoropoulou, Andriana, Jurković, Anita Penić, Kassianos, Angelos P., Findor, Andrej, Hartanto, Andree, Thibault Landry, Anais, Ferreira, Ana, Santos, Anabela Caetano, De La Rosa-gomez, Anabel, Gourdon-kanhukamwe, Amélie, Todsen, Anna Louise, Karababa, Alper, Janak, Allison, Bran, Alexandre, Tullett, Alexa M., Kuzminska, Anna O., Krafnick, Anthony J, Urooj, Anum, Khaoudi, Ahmed, Ahmed, Afroja, Groyecka-bernard, Agata, Askelund, Adrian Dahl, Adetula, Adeyemi, Belaus, Anabel, Charyate, Abdelilah Ca, Wichman, Aaron L., Stoyanova, Alina, Greenburgh, Anna, Thomas, Andrew G., Arvanitis, Alexios, Forscher, Patrick S., Mallik, Peter R, Primbs, Maximilian A., Miller, Jeremy K., Moshontz, Hannah, Urry, Heather L., Ijzerman, Hans, Basnight-brown, Dana M., Chartier, Christopher R., Buchanan, Erin M., Coles, Nicholas A., Dorison, Charles A., Lerner, Jennifer S., Heller, Blake H., Rothman, Alexander J., Kawachi, Ichiro I., Wang, Ke, Rees, Vaughan W., Gill, Brian P., Gibbs, Nancy, Ebersole, Charles R., Vally, Zahir, Tajchman, Zuzanna, Zsido, Andras N., Zrimsek, Mija, Chen, Zhang, Ziano, Ignazio, Gialitaki, Zoi, Ceary, Chris D., Lin, Yijun, Kunisato, Yoshihiko, Yamada, Yuki, Xiao, Qinyu, Jiang, Xiaoming, Du, Xinkai, Yao, Elvin, Wilson, John Paul, Cyrus-lai, Wilson, Jimenez-leal, William, Law, Wilbert, Collins, W. Matthew, Richard, Karley L., Vranka, Marek, Ankushev, Vladislav, Schei, Vidar, Križanić, Valerija, Kadreva, Veselina Hristova, Adoric, Vera Cubela, Tran, Ulrich S., Yeung, Siu Kit, Hassan, Widad, Houston, Ralph, Lima, Tiago J. S., Ostermann, Thomas, Frizzo, Thomas, Sverdrup, Therese E., House, Thea, Gill, Tripat, Fedotov, Maksim, Paltrow, Tamar, Jernsäther, Teodor, Koptjevskaja-tamm, Maria, Hostler, Thomas J., Ishii, Tatsunori, Szaszi, Barnabas, Adamus, Sylwia, Suter, Lilian, Habib, Sumaiya, Studzinska, Anna, Stojanovska, Dragana, Janssen, Steve M. J., Stieger, Stefan, Schulenberg, Stefan E., Tatachari, Srinivasan, Azouaghe, Soufian, Sorokowski, Piotr, Sorokowska, Agnieszka, Song, Xin, Lewis, Savannah C., Sinkolova, Sladjana, Grigoryev, Dmitry, Drexler, Shira Meir, Daches, Shimrit, Geniole, Shawn N., Vračar, Selena, Massoni, Sébastien, Zorjan, Saša, Sarıoğuz, Eylül, Izquierdo, Sara Morales, Alves, Sara G., Pöntinen, Sara, Solas, Sara Álvarez, Ordoñez-riaño, Santiago, Očovaj, Sanja Batić, Onie, Sandersan, Lins, Samuel, Çoksan, Sami, Sacakli, Asli, Ruiz-fernández, Susana, Geiger, Sandra J., Fatahmodares, Saeideh, Walczak, Radoslaw B., Betlehem, Ruben, Vilar, Roosevelt, Cárcamo, Rodrigo, Ross, Robert M., Mccarthy, Randy, Ballantyne, Tonia, Westgate, Erin C., Afhami, Reza, Ren, Dongning, Monteiro, Renan P., Reips, Ulf-dietrich, Reggev, Niv, Calin-jageman, Robert J., Pourafshari, Razieh, Oliveira, Raquel, Nedelcheva-datsova, Mina, Rahal, Rima-maria, Ribeiro, Rafael R., Radtke, Theda, Searston, Rachel, Habte, Redeate, Zdybek, Przemysław, Chen, Sau-chin, Maturan, Princess Lovella G., Perillo, Jennifer T., Isager, Peder Mortvedt, Kačmár, Pavol, Macapagal, Paulo Manuel, Szwed, Paulina, Hanel, Paul H. P., Forbes, Paul A. G., Arriaga, Patrícia, Paris, Bastien, Papachristopoulos, Konstantinos, Correa, Pablo Sebastián, Kácha, Ondřej, Bernardo, Márcia, Campos, Olatz, Bravo, Olalla Niño, Galindo-caballero, Oscar J., Ogbonnaya, Chisom Esther, Bialobrzeska, Olga, Kiselnikova, Natalia, Simonovic, Nicolle, Cohen, Noga, Nock, Nora L., Johannes, Niklas, Albayrak-aydemir, Nihan, Say, Nicolas, Torunsky, Nathan, Van Doren, Natalia, Sunami, Naoyuki, Rachev, Nikolay R., Majeed, Nadyanna M., Schmidt, Nadya-daniela, Nadif, Khaoula, Corral-frías, Nadia S., Ouherrou, Nihal, Pantazi, Myrto, Lucas, Marc Y., Vasilev, Martin R., Ortiz, María Victoria, Butt, Muhammad Mussaffa, Kabir, Muhib, Muda, Rafał, Tejada Rivera, Maria Del Carmen Mc, Sirota, Miroslav, Seehuus, Martin, Parzuchowski, Michal, Toro, Mónica, Hricova, Monika, Maldonado, Mónica Alarcón, Marszalek, Magdalena, Karekla, Maria, Mioni, Giovanna, Bosma, Minke Jasmijn, Westerlund, Minja, Vdovic, Milica, Bialek, Michal, Silan, Miguel A., Anne, Michele, Misiak, Michal, Grinberg, Maurice, Capizzi, Mariagrazia, Espinoza Barría, Mauricio F., Kurfali, Merve A., Mensink, Michael C., Harutyunyan, Mikayel, Khosla, Meetu, Korbmacher, Max, Adamkovič, Matúš, Ribeiro, Matheus Fernando Felix, Terskova, Maria, Hruška, Matej, Martončik, Marcel, Voracek, Martin, Čadek, Martin, Frías-armenta, Martha, Kowal, Marta, Topor, Marta, Roczniewska, Marta, Oosterlinck, Marlies, Kohlová, Markéta Braun, Paruzel-czachura, Mariola, Romanova, Marina, Papadatou-pastou, Marietta, Lund, Maria Louise, Antoniadi, Maria, Jones, Marc V., Ortiz, Manuel S., Manavalan, Mathi, Muminov, Abdumalik, Kossowska, Małgorzata, Friedemann, Maja, Wielgus, Magdalena, Varella, Marco A. C., Colloff, Melissa F., Bradford, Maria, Vaughn, Leigh Ann, Eudave, Luis, Vieira, Luc, Pineda, Lina Maria Sanabria, Pérez, Laura Calderón, Lazarevic, Ljiljana B., Jaremka, Lisa M., Kushnir, Elizaveta, Anton-boicuk, Lisa, De Holanda Coelho, Gabriel Lins, Ahlgren, Lina, Levitan, Carmel A., Micheli, Leticia, Volz, Leonhard, Stojanovska, Marija, Boucher, Leanne, Samojlenko, Lara, Delgado, Lady Grey Javela, Kaliska, Lada, Warmelink, Lara, Rojas-berscia, Luis Miguel, Yu, Karen, Wachowicz, Jakub, Desai, Kermeka, Barzykowski, Krystian, Kozma, Luca, Evans, Kortnee, Kirgizova, Komila, Agesin, Bamikole Emmanuel, Koehn, Monica A, Wolfe, Kelly, Korobova, Tatiana, Klevjer, Kristoffer, Van Schie, Kevin, Vezirian, Kevin, Damnjanović, Kaja, Thommesen, Katrine Krabbe, Schmidt, Kathleen, Filip, Katarzyna, Grzech, Karolina, Hoyer, Karlijn, Moon, Karis, Rana, Kafeel, Janjić, Kristina, Suchow, Jordan W., Kielińska, Julita, Cruz Vásquez, Julio E, Beitner, Julia, Vargas-nieto, Juan Camilo, Roxas, Jose Carlos T., Taber, Jennifer, Urriago-rayo, Joan, Pavlacic, Jeffrey M., Bavolar, Jozef, Soto, José A., Olofsson, Jonas K., Vilsmeier, Johannes K., Messerschmidt, Johanna, Czamanski-cohen, Johanna, Boudesseul, Jordane, Lee, Jeong Min, Kamburidis, Julia, Zickfeld, Janis, Miranda, Jacob F., Verharen, Jeroen P. H., Hristova, Evgeniya, Beshears, Julie E., Đorđević, Jasna Milošević, Bosch, Jasmijn, Valentova, Jaroslava Varella, Antfolk, Jan, Berkessel, Jana B., Schrötter, Jana, Urban, Jan, Röer, Jan Philipp, Norton, James O, Silva, Jaime R., Pickering, Jade S., Vintr, Jáchym, Uttley, Jim, Kunst, Jonas R., Ndukaihe, Izuchukwu L. G., Iyer, Aishwarya, Vilares, Iris, Ivanov, Aleksandr, Ropovik, Ivan, Sula, Isabela, Sarieva, Irena, Metin-orta, Irem, Prusova, Irina, Pinto, Isabel, Bozdoc, Andreea Ioana, Almeida, Inês A. T., Pit, Ilse L., Dalgar, Ilker, Zakharov, Ilya, Arinze, Azuka Ikechukwu, Ihaya, Keiko, Stephen, Ian D., Gjoneska, Biljana, Brohmer, Hilmar, Flowe, Heather, Godbersen, Hendrik, Kocalar, Halil Emre, Hedgebeth, Mattie V., Chuan-peng, Hu, Sharifian, Mohammadhasan, Manley, Harry, Akkas, Handan, Hajdu, Nandor, Azab, Habiba, Kaminski, Gwenael, Nilsonne, Gustav, Anjum, Gulnaz, Travaglino, Giovanni A., Feldman, Gilad, Pfuhl, Gerit, Czarnek, Gabriela, Marcu, Gabriela Mariana, Hofer, Gabriela, Banik, Gabriel, Adetula, Gabriel Agboola, Bijlstra, Gijsbert, Verbruggen, Frederick, Kung, Franki Y. H., Foroni, Francesco, Singer, Gage, Muchembled, Fany, Azevedo, Flavio, Mosannenzadeh, Farnaz, Marinov, Evelina, Štrukelj, Eva, Etebari, Zahra, Baskin, Ernest, Garcia, Elkin Oswaldo Luis, Musser, Erica, Van Steenkiste, I.m.m., Ahn, El Rim, Pronizius, Ekaterina, Jackson, Emily A, Manunta, Efisio, Agadullina, Elena, Šakan, Dušana, Dursun, Pinar, Dujols, Olivier, Dubrov, Dmitrii, Willis, Megan, Tümer, Murat, Beaudry, Jennifer L., Popović, Dora, Dunleavy, Daniel, Djamai, Ikhlas, Krupić, Dino, Vega, Diego, Du, Hongfei, Mola, Débora, Davis, William E., Holford, Dawn Liu, Lewis, David M. G., Vaidis, David C., Ozery, Daphna Hausman, Ricaurte, Danilo Zambrano, Storage, Daniel, Sousa, Daniela, Alvarez, Daniela Serrato, Rosa, Anna Dalla, Krupić, Dajana, Marko, Dafne, Moreau, David, Reeck, Crystal, Correia, Rita C., Whitt, Cassie M., Lamm, Claus, Solorzano, Claudio Singh, Von Bastian, Claudia C., Sutherland, Clare Am, Overkott, Clara, Aberson, Christopher L., Wang, Chunhui, Karashiali, Christiana, Noone, Chris, Chiu, Faith, Picciocchi, Chiara, Karaarslan, Cemre, Cellini, Nicola, Esteban-serna, Celia, Reyna, Cecilia, Batres, Carlota, Li, Ranran, Grano, Caterina, Carpentier, Joelle, Tamnes, Christian K., Fu, Cynthia H.y., Ishkhanyan, Byurakn, Bylinina, Lisa, Jaeger, Bastian, Bundt, Carsten, Allred, Tara Bulut, Bokkour, Ahmed, Bogatyreva, Natalia, Chopik, William J., Antazo, Benedict, Behzadnia, Behzad, Becker, Maja, Cocco, Beatrice, Chou, Wei-lun, Hubena, Barbora, Žuro, Barbara, Aczel, Balazs, Baklanova, Ekaterina, Bai, Hui, Balci, Busra Bahar, Babinčák, Peter, Dixson, Barnaby James Wyld, Mokady, Aviv, Kappes, Heather Barry, Atari, Mohammad, Szala, Anna, Szabelska, Anna, Aruta, John Jamir Benzon, Domurat, Artur, Arinze, Nwadiogo Chisom, Modena, Arianna, Adiguzel, Arca, Monajem, Arash, Arabi, Kanza Ait El, Özdoğru, Asil Ali, Olaya Torres, Adriana Julieth, Theodoropoulou, Andriana, Jurković, Anita Penić, Kassianos, Angelos P., Findor, Andrej, Hartanto, Andree, Thibault Landry, Anais, Ferreira, Ana, Santos, Anabela Caetano, De La Rosa-gomez, Anabel, Gourdon-kanhukamwe, Amélie, Todsen, Anna Louise, Karababa, Alper, Janak, Allison, Bran, Alexandre, Tullett, Alexa M., Kuzminska, Anna O., Krafnick, Anthony J, Urooj, Anum, Khaoudi, Ahmed, Ahmed, Afroja, Groyecka-bernard, Agata, Askelund, Adrian Dahl, Adetula, Adeyemi, Belaus, Anabel, Charyate, Abdelilah Ca, Wichman, Aaron L., Stoyanova, Alina, Greenburgh, Anna, Thomas, Andrew G., Arvanitis, Alexios, Forscher, Patrick S., Mallik, Peter R, Primbs, Maximilian A., Miller, Jeremy K., Moshontz, Hannah, Urry, Heather L., Ijzerman, Hans, Basnight-brown, Dana M., Chartier, Christopher R., Buchanan, Erin M., and Coles, Nicholas A.

Abstract

The COVID-19 pandemic (and its aftermath) highlights a critical need to communicate health information effectively to the global public. Given that subtle differences in information framing can have meaningful effects on behavior, behavioral science research highlights a pressing question: Is it more effective to frame COVID-19 health messages in terms of potential losses (e.g., “If you do not practice these steps, you can endanger yourself and others”) or potential gains (e.g., “If you practice these steps, you can protect yourself and others”)? Collecting data in 48 languages from 15,929 participants in 84 countries, we experimentally tested the effects of message framing on COVID-19-related judgments, intentions, and feelings. Loss- (vs. gain-) framed messages increased self-reported anxiety among participants cross-nationally with little-to-no impact on policy attitudes, behavioral intentions, or information seeking relevant to pandemic risks. These results were consistent across 84 countries, three variations of the message framing wording, and 560 data processing and analytic choices. Thus, results provide an empirical answer to a global communication question and highlight the emotional toll of loss-framed messages. Critically, this work demonstrates the importance of considering unintended affective consequences when evaluating nudge-style interventions.

165. The psychological science accelerator’s COVID-19 rapid-response dataset

Author

Buchanan, Erin M., Lewis, Savannah C., Paris, Bastien, Forscher, Patrick S., Pavlacic, Jeffrey M., Beshears, Julie E., Drexler, Shira Meir, Gourdon-Kanhukamwe, Amélie, Mallik, Peter R., Silan, Miguel Alejandro A., Miller, Jeremy K., IJzerman, Hans, Moshontz, Hannah, Beaudry, Jennifer L., Suchow, Jordan W., Chartier, Christopher R., Coles, Nicholas A., Sharifian, Mohammad Hasan, Todsen, Anna Louise, Levitan, Carmel A., Azevedo, Flávio, Legate, Nicole, Heller, Blake, Rothman, Alexander J., Dorison, Charles A., Gill, Brian P., Wang, Ke, Rees, Vaughan W., Gibbs, Nancy, Goldenberg, Amit, Thi Nguyen, Thuy vy, Gross, James J., Kaminski, Gwenaêl, von Bastian, Claudia C., Paruzel-Czachura, Mariola, Mosannenzadeh, Farnaz, Azouaghe, Soufian, Bran, Alexandre, Ruiz-Fernandez, Susana, Santos, Anabela Caetano, Reggev, Niv, Zickfeld, Janis H., Akkas, Handan, Pantazi, Myrto, Ropovik, Ivan, Korbmacher, Max, Arriaga, Patrícia, Gjoneska, Biljana, Warmelink, Lara, Alves, Sara G., de Holanda Coelho, Gabriel Lins, Stieger, Stefan, Schei, Vidar, Hanel, Paul H.P., Szaszi, Barnabas, Fedotov, Maksim, Antfolk, Jan, Marcu, Gabriela Mariana, Schrötter, Jana, Kunst, Jonas R., Geiger, Sandra J., Adetula, Adeyemi, Kocalar, Halil Emre, Kielińska, Julita, Kačmár, Pavol, Bokkour, Ahmed, Galindo-Caballero, Oscar J., Djamai, Ikhlas, Pöntinen, Sara Johanna, Agesin, Bamikole Emmanuel, Jernsäther, Teodor, Urooj, Anum, Rachev, Nikolay R., Koptjevskaja-Tamm, Maria, Kurfalı, Murathan, Pit, Ilse L., Li, Ranran, Çoksan, Sami, Dubrov, Dmitrii, Paltrow, Tamar Elise, Baník, Gabriel, Korobova, Tatiana, Studzinska, Anna, Jiang, Xiaoming, Aruta, John Jamir Benzon R., Vintr, Jáchym, Chiu, Faith, Kaliska, Lada, Berkessel, Jana B., Tümer, Murat, Morales-Izquierdo, Sara, Chuan-Peng, Hu, Vezirian, Kevin, Rosa, Anna Dalla, Bialobrzeska, Olga, Vasilev, Martin R., Beitner, Julia, Kácha, Ondřej, Žuro, Barbara, Westerlund, Minja, Nedelcheva-Datsova, Mina, Findor, Andrej, Krupić, Dajana, Kowal, Marta, Askelund, Adrian Dahl, Pourafshari, Razieh, Đorđević, Jasna Milošević, Schmidt, Nadya Daniela, Baklanova, Ekaterina, Szala, Anna, Zakharov, Ilya, Vranka, Marek A., Ihaya, Keiko, Grano, Caterina, Cellini, Nicola, Białek, Michał, Anton-Boicuk, Lisa, Dalgar, Ilker, Adıgüzel, Arca, Verharen, Jeroen P.H., Maturan, Princess Lovella G., Kassianos, Angelos P., Oliveira, Raquel, Čadek, Martin, Adoric, Vera Cubela, Özdoğru, Asil Ali, Sverdrup, Therese E., Aczel, Balazs, Zambrano, Danilo, Ahmed, Afroja, Tamnes, Christian K., Yamada, Yuki, Volz, Leonhard, Sunami, Naoyuki, Suter, Lilian, Vieira, Luc, Groyecka-Bernard, Agata, Kamburidis, Julia Arhondis, Reips, Ulf Dietrich, Harutyunyan, Mikayel, Adetula, Gabriel Agboola, Allred, Tara Bulut, Barzykowski, Krystian, Antazo, Benedict G., Zsido, Andras N., Šakan, Dušana Dušan, Cyrus-Lai, Wilson, Ahlgren, Lina Pernilla, Hruška, Matej, Vega, Diego, Manunta, Efisio, Mokady, Aviv, Capizzi, Mariagrazia, Martončik, Marcel, Say, Nicolas, Filip, Katarzyna, Vilar, Roosevelt, Staniaszek, Karolina, Vdovic, Milica, Adamkovic, Matus, Johannes, Niklas, Hajdu, Nandor, Cohen, Noga, Overkott, Clara, Krupić, Dino, Hubena, Barbora, Nilsonne, Gustav, Mioni, Giovanna, Solorzano, Claudio Singh, Ishii, Tatsunori, Chen, Zhang, Kushnir, Elizaveta, Karaarslan, Cemre, Ribeiro, Rafael R., Khaoudi, Ahmed, Kossowska, Małgorzata, Bavolar, Jozef, Hoyer, Karlijn, Roczniewska, Marta, Karababa, Alper, Becker, Maja, Monteiro, Renan P., Kunisato, Yoshihiko, Metin-Orta, Irem, Adamus, Sylwia, Kozma, Luca, Czarnek, Gabriela, Domurat, Artur, Štrukelj, Eva, Alvarez, Daniela Serrato, Parzuchowski, Michal, Massoni, Sébastien, Czamanski-Cohen, Johanna, Pronizius, Ekaterina, Muchembled, Fany, van Schie, Kevin, Saçaklı, Aslı, Hristova, Evgeniya, Kuzminska, Anna O., Charyate, Abdelilah, Bijlstra, Gijsbert, Afhami, Reza, Majeed, Nadyanna M., Musser, Erica D., Sirota, Miroslav, Ross, Robert M., Yeung, Siu Kit, Papadatou-Pastou, Marietta, Foroni, Francesco, Almeida, Inês A.T., Grigoryev, Dmitry, Lewis, David M.G., Holford, Dawn L., Janssen, Steve M.J., Tatachari, Srinivasan, Batres, Carlota, Olofsson, Jonas K., Daches, Shimrit, Belaus, Anabel, Pfuhl, Gerit, Corral-Frias, Nadia Sarai, Sousa, Daniela, Röer, Jan Philipp, Isager, Peder Mortvedt, Godbersen, Hendrik, Walczak, Radoslaw B., Van Doren, Natalia, Ren, Dongning, Gill, Tripat, Voracek, Martin, DeBruine, Lisa M., Anne, Michele, Očovaj, Sanja Batić, Thomas, Andrew G., Arvanitis, Alexios, Ostermann, Thomas, Wolfe, Kelly, Arinze, Nwadiogo Chisom, Bundt, Carsten, Lamm, Claus, Calin-Jageman, Robert J., Davis, William E., Karekla, Maria, Zorjan, Saša, Jaremka, Lisa M., Uttley, Jim, Hricova, Monika, Koehn, Monica A., Kiselnikova, Natalia, Bai, Hui, Krafnick, Anthony J., Balci, Busra Bahar, Ballantyne, Tonia, Lins, Samuel, Vally, Zahir, Esteban-Serna, Celia, Schmidt, Kathleen, Macapagal, Paulo Manuel L., Szwed, Paulina, Zdybek, Przemysław Marcin, Moreau, David, Collins, W. Matthew, Joy-Gaba, Jennifer A., Vilares, Iris, Tran, Ulrich S., Boudesseul, Jordane, Albayrak-Aydemir, Nihan, Dixson, Barnaby James Wyld, Perillo, Jennifer T., Ferreira, Ana, Westgate, Erin C., Aberson, Christopher L., Arinze, Azuka Ikechukwu, Jaeger, Bastian, Butt, Muhammad Mussaffa, Silva, Jaime R., Storage, Daniel Shafik, Janak, Allison P., Jiménez-Leal, William, Soto, Jose A., Sorokowska, Agnieszka, McCarthy, Randy, Tullett, Alexa M., Frias-Armenta, Martha, Ribeiro, Matheus Fernando Felix, Hartanto, Andree, Forbes, Paul A.G., Willis, Megan L., del Carmen Tejada R, María, Torres, Adriana Julieth Olaya, Stephen, Ian D., Vaidis, David C., de la Rosa-Gómez, Anabel, Yu, Karen, Sutherland, Clare A.M., Manavalan, Mathi, Behzadnia, Behzad, Urban, Jan, Baskin, Ernest, McFall, Joseph P., Ogbonnaya, Chisom Esther, Fu, Cynthia H.Y., Rahal, Rima Maria, Ndukaihe, Izuchukwu L.G., Hostler, Thomas J., Kappes, Heather Barry, Sorokowski, Piotr, Khosla, Meetu, Lazarevic, Ljiljana B., Eudave, Luis, Vilsmeier, Johannes K., Luis, Elkin O., Muda, Rafał, Agadullina, Elena, Cárcamo, Rodrigo A., Reeck, Crystal, Anjum, Gulnaz, Venegas, Mónica Camila Toro, Misiak, Michal, Ryan, Richard M., Nock, Nora L., Travaglino, Giovanni A., Mensink, Michael C., Feldman, Gilad, Wichman, Aaron L., Chou, Weilun, Ziano, Ignazio, Seehuus, Martin, Chopik, William J., Kung, Franki Y.H., Carpentier, Joelle, Vaughn, Leigh Ann, Du, Hongfei, Xiao, Qinyu, Lima, Tiago J.S., Noone, Chris, Onie, Sandersan, Verbruggen, Frederick, Radtke, Theda, Primbs, Maximilian A., Lewis, David M. G., Buchanan, Erin M., Lewis, Savannah C., Paris, Bastien, Forscher, Patrick S., Pavlacic, Jeffrey M., Beshears, Julie E., Drexler, Shira Meir, Gourdon-Kanhukamwe, Amélie, Mallik, Peter R., Silan, Miguel Alejandro A., Miller, Jeremy K., IJzerman, Hans, Moshontz, Hannah, Beaudry, Jennifer L., Suchow, Jordan W., Chartier, Christopher R., Coles, Nicholas A., Sharifian, Mohammad Hasan, Todsen, Anna Louise, Levitan, Carmel A., Azevedo, Flávio, Legate, Nicole, Heller, Blake, Rothman, Alexander J., Dorison, Charles A., Gill, Brian P., Wang, Ke, Rees, Vaughan W., Gibbs, Nancy, Goldenberg, Amit, Thi Nguyen, Thuy vy, Gross, James J., Kaminski, Gwenaêl, von Bastian, Claudia C., Paruzel-Czachura, Mariola, Mosannenzadeh, Farnaz, Azouaghe, Soufian, Bran, Alexandre, Ruiz-Fernandez, Susana, Santos, Anabela Caetano, Reggev, Niv, Zickfeld, Janis H., Akkas, Handan, Pantazi, Myrto, Ropovik, Ivan, Korbmacher, Max, Arriaga, Patrícia, Gjoneska, Biljana, Warmelink, Lara, Alves, Sara G., de Holanda Coelho, Gabriel Lins, Stieger, Stefan, Schei, Vidar, Hanel, Paul H.P., Szaszi, Barnabas, Fedotov, Maksim, Antfolk, Jan, Marcu, Gabriela Mariana, Schrötter, Jana, Kunst, Jonas R., Geiger, Sandra J., Adetula, Adeyemi, Kocalar, Halil Emre, Kielińska, Julita, Kačmár, Pavol, Bokkour, Ahmed, Galindo-Caballero, Oscar J., Djamai, Ikhlas, Pöntinen, Sara Johanna, Agesin, Bamikole Emmanuel, Jernsäther, Teodor, Urooj, Anum, Rachev, Nikolay R., Koptjevskaja-Tamm, Maria, Kurfalı, Murathan, Pit, Ilse L., Li, Ranran, Çoksan, Sami, Dubrov, Dmitrii, Paltrow, Tamar Elise, Baník, Gabriel, Korobova, Tatiana, Studzinska, Anna, Jiang, Xiaoming, Aruta, John Jamir Benzon R., Vintr, Jáchym, Chiu, Faith, Kaliska, Lada, Berkessel, Jana B., Tümer, Murat, Morales-Izquierdo, Sara, Chuan-Peng, Hu, Vezirian, Kevin, Rosa, Anna Dalla, Bialobrzeska, Olga, Vasilev, Martin R., Beitner, Julia, Kácha, Ondřej, Žuro, Barbara, Westerlund, Minja, Nedelcheva-Datsova, Mina, Findor, Andrej, Krupić, Dajana, Kowal, Marta, Askelund, Adrian Dahl, Pourafshari, Razieh, Đorđević, Jasna Milošević, Schmidt, Nadya Daniela, Baklanova, Ekaterina, Szala, Anna, Zakharov, Ilya, Vranka, Marek A., Ihaya, Keiko, Grano, Caterina, Cellini, Nicola, Białek, Michał, Anton-Boicuk, Lisa, Dalgar, Ilker, Adıgüzel, Arca, Verharen, Jeroen P.H., Maturan, Princess Lovella G., Kassianos, Angelos P., Oliveira, Raquel, Čadek, Martin, Adoric, Vera Cubela, Özdoğru, Asil Ali, Sverdrup, Therese E., Aczel, Balazs, Zambrano, Danilo, Ahmed, Afroja, Tamnes, Christian K., Yamada, Yuki, Volz, Leonhard, Sunami, Naoyuki, Suter, Lilian, Vieira, Luc, Groyecka-Bernard, Agata, Kamburidis, Julia Arhondis, Reips, Ulf Dietrich, Harutyunyan, Mikayel, Adetula, Gabriel Agboola, Allred, Tara Bulut, Barzykowski, Krystian, Antazo, Benedict G., Zsido, Andras N., Šakan, Dušana Dušan, Cyrus-Lai, Wilson, Ahlgren, Lina Pernilla, Hruška, Matej, Vega, Diego, Manunta, Efisio, Mokady, Aviv, Capizzi, Mariagrazia, Martončik, Marcel, Say, Nicolas, Filip, Katarzyna, Vilar, Roosevelt, Staniaszek, Karolina, Vdovic, Milica, Adamkovic, Matus, Johannes, Niklas, Hajdu, Nandor, Cohen, Noga, Overkott, Clara, Krupić, Dino, Hubena, Barbora, Nilsonne, Gustav, Mioni, Giovanna, Solorzano, Claudio Singh, Ishii, Tatsunori, Chen, Zhang, Kushnir, Elizaveta, Karaarslan, Cemre, Ribeiro, Rafael R., Khaoudi, Ahmed, Kossowska, Małgorzata, Bavolar, Jozef, Hoyer, Karlijn, Roczniewska, Marta, Karababa, Alper, Becker, Maja, Monteiro, Renan P., Kunisato, Yoshihiko, Metin-Orta, Irem, Adamus, Sylwia, Kozma, Luca, Czarnek, Gabriela, Domurat, Artur, Štrukelj, Eva, Alvarez, Daniela Serrato, Parzuchowski, Michal, Massoni, Sébastien, Czamanski-Cohen, Johanna, Pronizius, Ekaterina, Muchembled, Fany, van Schie, Kevin, Saçaklı, Aslı, Hristova, Evgeniya, Kuzminska, Anna O., Charyate, Abdelilah, Bijlstra, Gijsbert, Afhami, Reza, Majeed, Nadyanna M., Musser, Erica D., Sirota, Miroslav, Ross, Robert M., Yeung, Siu Kit, Papadatou-Pastou, Marietta, Foroni, Francesco, Almeida, Inês A.T., Grigoryev, Dmitry, Lewis, David M.G., Holford, Dawn L., Janssen, Steve M.J., Tatachari, Srinivasan, Batres, Carlota, Olofsson, Jonas K., Daches, Shimrit, Belaus, Anabel, Pfuhl, Gerit, Corral-Frias, Nadia Sarai, Sousa, Daniela, Röer, Jan Philipp, Isager, Peder Mortvedt, Godbersen, Hendrik, Walczak, Radoslaw B., Van Doren, Natalia, Ren, Dongning, Gill, Tripat, Voracek, Martin, DeBruine, Lisa M., Anne, Michele, Očovaj, Sanja Batić, Thomas, Andrew G., Arvanitis, Alexios, Ostermann, Thomas, Wolfe, Kelly, Arinze, Nwadiogo Chisom, Bundt, Carsten, Lamm, Claus, Calin-Jageman, Robert J., Davis, William E., Karekla, Maria, Zorjan, Saša, Jaremka, Lisa M., Uttley, Jim, Hricova, Monika, Koehn, Monica A., Kiselnikova, Natalia, Bai, Hui, Krafnick, Anthony J., Balci, Busra Bahar, Ballantyne, Tonia, Lins, Samuel, Vally, Zahir, Esteban-Serna, Celia, Schmidt, Kathleen, Macapagal, Paulo Manuel L., Szwed, Paulina, Zdybek, Przemysław Marcin, Moreau, David, Collins, W. Matthew, Joy-Gaba, Jennifer A., Vilares, Iris, Tran, Ulrich S., Boudesseul, Jordane, Albayrak-Aydemir, Nihan, Dixson, Barnaby James Wyld, Perillo, Jennifer T., Ferreira, Ana, Westgate, Erin C., Aberson, Christopher L., Arinze, Azuka Ikechukwu, Jaeger, Bastian, Butt, Muhammad Mussaffa, Silva, Jaime R., Storage, Daniel Shafik, Janak, Allison P., Jiménez-Leal, William, Soto, Jose A., Sorokowska, Agnieszka, McCarthy, Randy, Tullett, Alexa M., Frias-Armenta, Martha, Ribeiro, Matheus Fernando Felix, Hartanto, Andree, Forbes, Paul A.G., Willis, Megan L., del Carmen Tejada R, María, Torres, Adriana Julieth Olaya, Stephen, Ian D., Vaidis, David C., de la Rosa-Gómez, Anabel, Yu, Karen, Sutherland, Clare A.M., Manavalan, Mathi, Behzadnia, Behzad, Urban, Jan, Baskin, Ernest, McFall, Joseph P., Ogbonnaya, Chisom Esther, Fu, Cynthia H.Y., Rahal, Rima Maria, Ndukaihe, Izuchukwu L.G., Hostler, Thomas J., Kappes, Heather Barry, Sorokowski, Piotr, Khosla, Meetu, Lazarevic, Ljiljana B., Eudave, Luis, Vilsmeier, Johannes K., Luis, Elkin O., Muda, Rafał, Agadullina, Elena, Cárcamo, Rodrigo A., Reeck, Crystal, Anjum, Gulnaz, Venegas, Mónica Camila Toro, Misiak, Michal, Ryan, Richard M., Nock, Nora L., Travaglino, Giovanni A., Mensink, Michael C., Feldman, Gilad, Wichman, Aaron L., Chou, Weilun, Ziano, Ignazio, Seehuus, Martin, Chopik, William J., Kung, Franki Y.H., Carpentier, Joelle, Vaughn, Leigh Ann, Du, Hongfei, Xiao, Qinyu, Lima, Tiago J.S., Noone, Chris, Onie, Sandersan, Verbruggen, Frederick, Radtke, Theda, Primbs, Maximilian A., and Lewis, David M. G.

Abstract

In response to the COVID-19 pandemic, the Psychological Science Accelerator coordinated three large-scale psychological studies to examine the effects of loss-gain framing, cognitive reappraisals, and autonomy framing manipulations on behavioral intentions and affective measures. The data collected (April to October 2020) included specific measures for each experimental study, a general questionnaire examining health prevention behaviors and COVID-19 experience, geographical and cultural context characterization, and demographic information for each participant. Each participant started the study with the same general questions and then was randomized to complete either one longer experiment or two shorter experiments. Data were provided by 73,223 participants with varying completion rates. Participants completed the survey from 111 geopolitical regions in 44 unique languages/dialects. The anonymized dataset described here is provided in both raw and processed formats to facilitate re-use and further analyses. The dataset offers secondary analytic opportunities to explore coping, framing, and self-determination across a diverse, global sample obtained at the onset of the COVID-19 pandemic, which can be merged with other time-sampled or geographic data.

166. The Psychological Science Accelerator’s COVID-19 rapid-response dataset

Author

Buchanan, Erin M., Lewis, Savannah C., Paris, Bastien, Forscher, Patrick S., Pavlacic, Jeffrey M., Beshears, Julie E., Drexler, Shira Meir, Gourdon-Kanhukamwe, Amélie, Mallik, Peter R, Silan, Miguel Alejandro A., Miller, Jeremy K., IJzerman, Hans, Moshontz, Hannah, Beaudry, Jennifer L., Suchow, Jordan W., Chartier, Christopher R., Coles, Nicholas A., Sharifian, MohammadHasan, Todsen, Anna Louise, Levitan, Carmel A., Azevedo, Flávio, Legate, Nicole, Heller, Blake, Rothman, Alexander J., Dorison, Charles A., Gill, Brian P., Wang, Ke, Rees, Vaughan W., Gibbs, Nancy, Goldenberg, Amit, Thi Nguyen, Thuy-vy, Gross, James J., Kaminski, Gwenaêl, von Bastian, Claudia C., Paruzel-Czachura, Mariola, Mosannenzadeh, Farnaz, Azouaghe, Soufian, Bran, Alexandre, Ruiz-Fernandez, Susana, Santos, Anabela Caetano, Reggev, Niv, Zickfeld, Janis H., Akkas, Handan, Pantazi, Myrto, Ropovik, Ivan, Korbmacher, Max, Arriaga, Patrícia, Gjoneska, Biljana, Warmelink, Lara, Alves, Sara G., de Holanda Coelho, Gabriel Lins, Stieger, Stefan, Schei, Vidar, Hanel, Paul H. P., Szaszi, Barnabas, Fedotov, Maksim, Antfolk, Jan, Marcu, Gabriela-Mariana, Schrötter, Jana, Kunst, Jonas R., Geiger, Sandra J., Adetula, Adeyemi, Kocalar, Halil Emre, Kielińska, Julita, Kačmár, Pavol, Bokkour, Ahmed, Galindo-Caballero, Oscar J., Djamai, Ikhlas, Pöntinen, Sara Johanna, AGESIN, Bamikole Emmanuel, Jernsäther, Teodor, Urooj, Anum, Rachev, Nikolay R., Koptjevskaja-Tamm, Maria, Kurfalı, Murathan, Pit, Ilse L., Li, Ranran, Çoksan, Sami, Dubrov, Dmitrii, Paltrow, Tamar Elise, Baník, Gabriel, Korobova, Tatiana, Studzinska, Anna, Jiang, Xiaoming, Aruta, John Jamir Benzon R., Vintr, Jáchym, Chiu, Faith, Kaliska, Lada, Berkessel, Jana B., Tümer, Murat, Morales-Izquierdo, Sara, Chuan-Peng, Hu, Vezirian, Kevin, Rosa, Anna Dalla, Bialobrzeska, Olga, Vasilev, Martin R., Beitner, Julia, Kácha, Ondřej, Žuro, Barbara, Westerlund, Minja, Nedelcheva-Datsova, Mina, Findor, Andrej, Krupić, Dajana, Kowal, Marta, Askelund, Adrian Dahl, Pourafshari, Razieh, Đorđević, Jasna Milošević, Schmidt, Nadya-Daniela, Baklanova, Ekaterina, Szala, Anna, Zakharov, Ilya, Vranka, Marek A., Ihaya, Keiko, Grano, Caterina, Cellini, Nicola, Białek, Michał, Anton-Boicuk, Lisa, Dalgar, Ilker, Adıgüzel, Arca, Verharen, Jeroen P. H., Maturan, Princess Lovella G., Kassianos, Angelos P., Oliveira, Raquel, Čadek, Martin, Adoric, Vera Cubela, Özdoğru, Asil Ali, Sverdrup, Therese E., Aczel, Balazs, Zambrano, Danilo, Ahmed, Afroja, Tamnes, Christian K., Yamada, Yuki, Volz, Leonhard, Sunami, Naoyuki, Suter, Lilian, Vieira, Luc, Groyecka-Bernard, Agata, Kamburidis, Julia Arhondis, Reips, Ulf-Dietrich, Harutyunyan, Mikayel, Adetula, Gabriel Agboola, Allred, Tara Bulut, Barzykowski, Krystian, Antazo, Benedict G, Zsido, Andras N., Šakan, Dušana Dušan, Cyrus-Lai, Wilson, Ahlgren, Lina Pernilla, Hruška, Matej, Vega, Diego, Manunta, Efisio, Mokady, Aviv, Capizzi, Mariagrazia, Martončik, Marcel, Say, Nicolas, Filip, Katarzyna, Vilar, Roosevelt, Staniaszek, Karolina, Vdovic, Milica, Adamkovic, Matus, Johannes, Niklas, Hajdu, Nandor, Cohen, Noga, Overkott, Clara, Krupić, Dino, Hubena, Barbora, Nilsonne, Gustav, Mioni, Giovanna, Solorzano, Claudio Singh, Ishii, Tatsunori, Chen, Zhang, Kushnir, Elizaveta, Karaarslan, Cemre, Ribeiro, Rafael R., Khaoudi, Ahmed, Kossowska, Małgorzata, Bavolar, Jozef, Hoyer, Karlijn, Roczniewska, Marta, Karababa, Alper, Becker, Maja, Monteiro, Renan P., Kunisato, Yoshihiko, Metin-Orta, Irem, Adamus, Sylwia, Kozma, Luca, Czarnek, Gabriela, Domurat, Artur, Štrukelj, Eva, Alvarez, Daniela Serrato, Parzuchowski, Michal, Massoni, Sébastien, Czamanski-Cohen, Johanna, Pronizius, Ekaterina, Muchembled, Fany, van Schie, Kevin, Saçaklı, Aslı, Hristova, Evgeniya, Kuzminska, Anna O., Charyate, Abdelilah, Bijlstra, Gijsbert, Afhami, Reza, Majeed, Nadyanna M., Musser, Erica D., Sirota, Miroslav, Ross, Robert M., Yeung, Siu Kit, Papadatou-Pastou, Marietta, Foroni, Francesco, Almeida, Inês A. T., Grigoryev, Dmitry, Lewis, David M. G., Holford, Dawn L., Janssen, Steve M. J., Tatachari, Srinivasan, Batres, Carlota, Olofsson, Jonas K., Daches, Shimrit, Belaus, Anabel, Pfuhl, Gerit, Corral-Frias, Nadia Sarai, Sousa, Daniela, Röer, Jan Philipp, Isager, Peder Mortvedt, Godbersen, Hendrik, Walczak, Radoslaw B., Van Doren, Natalia, Ren, Dongning, Gill, Tripat, Voracek, Martin, DeBruine, Lisa M., Anne, Michele, Očovaj, Sanja Batić, Thomas, Andrew G., Arvanitis, Alexios, Ostermann, Thomas, Wolfe, Kelly, Arinze, Nwadiogo Chisom, Bundt, Carsten, Lamm, Claus, Calin-Jageman, Robert J, Davis, William E., Karekla, Maria, Zorjan, Saša, Jaremka, Lisa M., Uttley, Jim, Hricova, Monika, Koehn, Monica A, Kiselnikova, Natalia, Bai, Hui, Krafnick, Anthony J., Balci, Busra Bahar, Ballantyne, Tonia, Lins, Samuel, Vally, Zahir, Esteban-Serna, Celia, Schmidt, Kathleen, Macapagal, Paulo Manuel L., Szwed, Paulina, Zdybek, Przemysław Marcin, Moreau, David, Collins, W. Matthew, Joy-Gaba, Jennifer A., Vilares, Iris, Tran, Ulrich S., Boudesseul, Jordane, Albayrak-Aydemir, Nihan, Dixson, Barnaby James Wyld, Perillo, Jennifer T, Ferreira, Ana, Westgate, Erin C., Aberson, Christopher L., Arinze, Azuka Ikechukwu, Jaeger, Bastian, Butt, Muhammad Mussaffa, Silva, Jaime R., Storage, Daniel Shafik, Janak, Allison P, Jiménez-Leal, William, Soto, Jose A., Sorokowska, Agnieszka, McCarthy, Randy, Tullett, Alexa M, Frias-Armenta, Martha, Ribeiro, Matheus Fernando Felix, Hartanto, Andree, Forbes, Paul A. G., Willis, Megan L., del Carmen Tejada R, María, Torres, Adriana Julieth Olaya, Stephen, Ian D, Vaidis, David C., de la Rosa-Gómez, Anabel, Yu, Karen, Sutherland, Clare A. M., Manavalan, Mathi, Behzadnia, Behzad, Urban, Jan, Baskin, Ernest, McFall, Joseph P., Ogbonnaya, Chisom Esther, Fu, Cynthia H. Y., Rahal, Rima-Maria, Ndukaihe, Izuchukwu L. G., Hostler, Thomas J., Kappes, Heather Barry, Sorokowski, Piotr, Khosla, Meetu, Lazarevic, Ljiljana B., Eudave, Luis, Vilsmeier, Johannes K., Luis, Elkin O., Muda, Rafał, Agadullina, Elena, Cárcamo, Rodrigo A., Reeck, Crystal, Anjum, Gulnaz, Venegas, Mónica Camila Toro, Misiak, Michal, Ryan, Richard M., Nock, Nora L., Travaglino, Giovanni A., Mensink, Michael C., Feldman, Gilad, Wichman, Aaron L., Chou, Weilun, Ziano, Ignazio, Seehuus, Martin, Chopik, William J., Kung, Franki Y. H., Carpentier, Joelle, Vaughn, Leigh Ann, Du, Hongfei, Xiao, Qinyu, Lima, Tiago J. S., Noone, Chris, Onie, Sandersan, Verbruggen, Frederick, Radtke, Theda, Primbs, Maximilian A., Buchanan, Erin M., Lewis, Savannah C., Paris, Bastien, Forscher, Patrick S., Pavlacic, Jeffrey M., Beshears, Julie E., Drexler, Shira Meir, Gourdon-Kanhukamwe, Amélie, Mallik, Peter R, Silan, Miguel Alejandro A., Miller, Jeremy K., IJzerman, Hans, Moshontz, Hannah, Beaudry, Jennifer L., Suchow, Jordan W., Chartier, Christopher R., Coles, Nicholas A., Sharifian, MohammadHasan, Todsen, Anna Louise, Levitan, Carmel A., Azevedo, Flávio, Legate, Nicole, Heller, Blake, Rothman, Alexander J., Dorison, Charles A., Gill, Brian P., Wang, Ke, Rees, Vaughan W., Gibbs, Nancy, Goldenberg, Amit, Thi Nguyen, Thuy-vy, Gross, James J., Kaminski, Gwenaêl, von Bastian, Claudia C., Paruzel-Czachura, Mariola, Mosannenzadeh, Farnaz, Azouaghe, Soufian, Bran, Alexandre, Ruiz-Fernandez, Susana, Santos, Anabela Caetano, Reggev, Niv, Zickfeld, Janis H., Akkas, Handan, Pantazi, Myrto, Ropovik, Ivan, Korbmacher, Max, Arriaga, Patrícia, Gjoneska, Biljana, Warmelink, Lara, Alves, Sara G., de Holanda Coelho, Gabriel Lins, Stieger, Stefan, Schei, Vidar, Hanel, Paul H. P., Szaszi, Barnabas, Fedotov, Maksim, Antfolk, Jan, Marcu, Gabriela-Mariana, Schrötter, Jana, Kunst, Jonas R., Geiger, Sandra J., Adetula, Adeyemi, Kocalar, Halil Emre, Kielińska, Julita, Kačmár, Pavol, Bokkour, Ahmed, Galindo-Caballero, Oscar J., Djamai, Ikhlas, Pöntinen, Sara Johanna, AGESIN, Bamikole Emmanuel, Jernsäther, Teodor, Urooj, Anum, Rachev, Nikolay R., Koptjevskaja-Tamm, Maria, Kurfalı, Murathan, Pit, Ilse L., Li, Ranran, Çoksan, Sami, Dubrov, Dmitrii, Paltrow, Tamar Elise, Baník, Gabriel, Korobova, Tatiana, Studzinska, Anna, Jiang, Xiaoming, Aruta, John Jamir Benzon R., Vintr, Jáchym, Chiu, Faith, Kaliska, Lada, Berkessel, Jana B., Tümer, Murat, Morales-Izquierdo, Sara, Chuan-Peng, Hu, Vezirian, Kevin, Rosa, Anna Dalla, Bialobrzeska, Olga, Vasilev, Martin R., Beitner, Julia, Kácha, Ondřej, Žuro, Barbara, Westerlund, Minja, Nedelcheva-Datsova, Mina, Findor, Andrej, Krupić, Dajana, Kowal, Marta, Askelund, Adrian Dahl, Pourafshari, Razieh, Đorđević, Jasna Milošević, Schmidt, Nadya-Daniela, Baklanova, Ekaterina, Szala, Anna, Zakharov, Ilya, Vranka, Marek A., Ihaya, Keiko, Grano, Caterina, Cellini, Nicola, Białek, Michał, Anton-Boicuk, Lisa, Dalgar, Ilker, Adıgüzel, Arca, Verharen, Jeroen P. H., Maturan, Princess Lovella G., Kassianos, Angelos P., Oliveira, Raquel, Čadek, Martin, Adoric, Vera Cubela, Özdoğru, Asil Ali, Sverdrup, Therese E., Aczel, Balazs, Zambrano, Danilo, Ahmed, Afroja, Tamnes, Christian K., Yamada, Yuki, Volz, Leonhard, Sunami, Naoyuki, Suter, Lilian, Vieira, Luc, Groyecka-Bernard, Agata, Kamburidis, Julia Arhondis, Reips, Ulf-Dietrich, Harutyunyan, Mikayel, Adetula, Gabriel Agboola, Allred, Tara Bulut, Barzykowski, Krystian, Antazo, Benedict G, Zsido, Andras N., Šakan, Dušana Dušan, Cyrus-Lai, Wilson, Ahlgren, Lina Pernilla, Hruška, Matej, Vega, Diego, Manunta, Efisio, Mokady, Aviv, Capizzi, Mariagrazia, Martončik, Marcel, Say, Nicolas, Filip, Katarzyna, Vilar, Roosevelt, Staniaszek, Karolina, Vdovic, Milica, Adamkovic, Matus, Johannes, Niklas, Hajdu, Nandor, Cohen, Noga, Overkott, Clara, Krupić, Dino, Hubena, Barbora, Nilsonne, Gustav, Mioni, Giovanna, Solorzano, Claudio Singh, Ishii, Tatsunori, Chen, Zhang, Kushnir, Elizaveta, Karaarslan, Cemre, Ribeiro, Rafael R., Khaoudi, Ahmed, Kossowska, Małgorzata, Bavolar, Jozef, Hoyer, Karlijn, Roczniewska, Marta, Karababa, Alper, Becker, Maja, Monteiro, Renan P., Kunisato, Yoshihiko, Metin-Orta, Irem, Adamus, Sylwia, Kozma, Luca, Czarnek, Gabriela, Domurat, Artur, Štrukelj, Eva, Alvarez, Daniela Serrato, Parzuchowski, Michal, Massoni, Sébastien, Czamanski-Cohen, Johanna, Pronizius, Ekaterina, Muchembled, Fany, van Schie, Kevin, Saçaklı, Aslı, Hristova, Evgeniya, Kuzminska, Anna O., Charyate, Abdelilah, Bijlstra, Gijsbert, Afhami, Reza, Majeed, Nadyanna M., Musser, Erica D., Sirota, Miroslav, Ross, Robert M., Yeung, Siu Kit, Papadatou-Pastou, Marietta, Foroni, Francesco, Almeida, Inês A. T., Grigoryev, Dmitry, Lewis, David M. G., Holford, Dawn L., Janssen, Steve M. J., Tatachari, Srinivasan, Batres, Carlota, Olofsson, Jonas K., Daches, Shimrit, Belaus, Anabel, Pfuhl, Gerit, Corral-Frias, Nadia Sarai, Sousa, Daniela, Röer, Jan Philipp, Isager, Peder Mortvedt, Godbersen, Hendrik, Walczak, Radoslaw B., Van Doren, Natalia, Ren, Dongning, Gill, Tripat, Voracek, Martin, DeBruine, Lisa M., Anne, Michele, Očovaj, Sanja Batić, Thomas, Andrew G., Arvanitis, Alexios, Ostermann, Thomas, Wolfe, Kelly, Arinze, Nwadiogo Chisom, Bundt, Carsten, Lamm, Claus, Calin-Jageman, Robert J, Davis, William E., Karekla, Maria, Zorjan, Saša, Jaremka, Lisa M., Uttley, Jim, Hricova, Monika, Koehn, Monica A, Kiselnikova, Natalia, Bai, Hui, Krafnick, Anthony J., Balci, Busra Bahar, Ballantyne, Tonia, Lins, Samuel, Vally, Zahir, Esteban-Serna, Celia, Schmidt, Kathleen, Macapagal, Paulo Manuel L., Szwed, Paulina, Zdybek, Przemysław Marcin, Moreau, David, Collins, W. Matthew, Joy-Gaba, Jennifer A., Vilares, Iris, Tran, Ulrich S., Boudesseul, Jordane, Albayrak-Aydemir, Nihan, Dixson, Barnaby James Wyld, Perillo, Jennifer T, Ferreira, Ana, Westgate, Erin C., Aberson, Christopher L., Arinze, Azuka Ikechukwu, Jaeger, Bastian, Butt, Muhammad Mussaffa, Silva, Jaime R., Storage, Daniel Shafik, Janak, Allison P, Jiménez-Leal, William, Soto, Jose A., Sorokowska, Agnieszka, McCarthy, Randy, Tullett, Alexa M, Frias-Armenta, Martha, Ribeiro, Matheus Fernando Felix, Hartanto, Andree, Forbes, Paul A. G., Willis, Megan L., del Carmen Tejada R, María, Torres, Adriana Julieth Olaya, Stephen, Ian D, Vaidis, David C., de la Rosa-Gómez, Anabel, Yu, Karen, Sutherland, Clare A. M., Manavalan, Mathi, Behzadnia, Behzad, Urban, Jan, Baskin, Ernest, McFall, Joseph P., Ogbonnaya, Chisom Esther, Fu, Cynthia H. Y., Rahal, Rima-Maria, Ndukaihe, Izuchukwu L. G., Hostler, Thomas J., Kappes, Heather Barry, Sorokowski, Piotr, Khosla, Meetu, Lazarevic, Ljiljana B., Eudave, Luis, Vilsmeier, Johannes K., Luis, Elkin O., Muda, Rafał, Agadullina, Elena, Cárcamo, Rodrigo A., Reeck, Crystal, Anjum, Gulnaz, Venegas, Mónica Camila Toro, Misiak, Michal, Ryan, Richard M., Nock, Nora L., Travaglino, Giovanni A., Mensink, Michael C., Feldman, Gilad, Wichman, Aaron L., Chou, Weilun, Ziano, Ignazio, Seehuus, Martin, Chopik, William J., Kung, Franki Y. H., Carpentier, Joelle, Vaughn, Leigh Ann, Du, Hongfei, Xiao, Qinyu, Lima, Tiago J. S., Noone, Chris, Onie, Sandersan, Verbruggen, Frederick, Radtke, Theda, and Primbs, Maximilian A.

Abstract

In response to the COVID-19 pandemic, the Psychological Science Accelerator coordinated three large-scale psychological studies to examine the effects of loss-gain framing, cognitive reappraisals, and autonomy framing manipulations on behavioral intentions and affective measures. The data collected (April to October 2020) included specific measures for each experimental study, a general questionnaire examining health prevention behaviors and COVID-19 experience, geographical and cultural context characterization, and demographic information for each participant. Each participant started the study with the same general questions and then was randomized to complete either one longer experiment or two shorter experiments. Data were provided by 73,223 participants with varying completion rates. Participants completed the survey from 111 geopolitical regions in 44 unique languages/dialects. The anonymized dataset described here is provided in both raw and processed formats to facilitate re-use and further analyses. The dataset offers secondary analytic opportunities to explore coping, framing, and self-determination across a diverse, global sample obtained at the onset of the COVID-19 pandemic, which can be merged with other time-sampled or geographic data.

167. Addressing climate change with behavioral science: a global intervention tournament in 63 countries

Author

Vlasceanu, Madalina, Doell, Kimberly C., Bak-Coleman, Joseph b., Todorova, Boryana, Berkebile-Weinberg, Michael M., Grayson, Samantha j., Patel, Yash, Goldwert, Danielle, Pei, Yifei, Chakroff, Alek, Pronizius, Ekaterina, Van den broek, Karlijn l., Vlasceanu, Denisa, Constantino, Sara, Morais, Michael J., Schumann, Philipp, Rathje, Steve, Fang, Ke, Aglioti, Salvatore maria, Alfano, Mark, Alvarado-Yepez, Andy J., Andersen, Angélica, Anseel, Frederik, Apps, Matthew A. J., Asadli, Chillar, Awuor, Fonda Jane, Azevedo, Flavio, Basaglia, Piero, Bélanger, Jocelyn J., Berger, Sebastian, Bertin, Paul, Białek, Michał, Bialobrzeska, Olga, Blaya-Burgo, Michelle, Bleize, Daniëlle N. M., Bø, Simen, Boecker, Lea, Boggio, Paulo S., Borau, Sylvie, Bos, Björn, Bouguettaya, Ayoub, Brauer, Markus, Brick, Cameron, Brik, Tymofii, Briker, Roman, Brosch, Tobias, Buchel, Ondrej, Buonauro, Daniel, Butalia, Radhika, Carvacho, Héctor, Chamberlain, Sarah A. E., Chan, Hang-Yee, Chow, Dawn, Chung, Dongil, Cian, Luca, Cohen-Eick, Noa, Contreras-Huerta, Luis sebastian, Contu, Davide, Cristea, Vladimir, Cutler, Jo, D'ottone, Silvana, De keersmaecker, Jonas, Delcourt, Sarah, Delouvée, Sylvain, Diel, Kathi, Douglas, Benjamin d., Drupp, Moritz a., Dubey, Shreya, Ekmanis, Jānis, Elbaek, Christian t., Elsherif, Mahmoud, Engelhard, Iris m., Escher, Yannik a., Etienne, Tom W., Farage, Laura, Farias, Ana Rita, Feuerriegel, Stefan, Findor, Andrej, Freira, Lucia, Friese, Malte, Gains, Neil philip, Gallyamova, Albina, Geiger, Sandra j., Genschow, Oliver, Gjoneska, Biljana, Gkinopoulos, Theofilos, Goldberg, Beth, Goldenberg, Amit, Gradidge, Sarah, Grassini, Simone, Gray, Kurt, Grelle, Sonja, Griffin, Siobhán m., Grigoryan, Lusine, Grigoryan, Ani, Grigoryev, Dmitry, Gruber, June, Guilaran, Johnrev, Hadar, Britt, Hahnel, Ulf j.j., Halperin, Eran, Harvey, Annelie j., Haugestad, Christian a. p., Herman, Aleksandra M., Hershfield, Hal E., Himichi, Toshiyuki, Hine, Donald W., Hofmann, Wilhelm, Howe, Lauren, Huaman-Chulluncuy, Enma t., Huang, Guanxiong, Ishii, Tatsunori, Ito, Ayahito, Jia, Fanli, Jost, John T., Jovanović, Veljko, Jurgiel, Dominika, Kácha, Ondřej, Kankaanpää, Reeta, Kantorowicz, Jaroslaw, Kantorowicz-Reznichenko, Elena, Kaplan mintz, Keren, Kaya, Ilker, Kaya, Ozgur, Khachatryan, Narine, Klas, Anna, Klein, Colin, Klöckner, Christian a., Koppel, Lina, Kosachenko, Alexandra i., Kothe, Emily J., Krebs, Ruth, Krosch, Amy R., Krouwel, Andre P. M., Kyrychenko, Yara, Lagomarsino, Maria, Lamm, Claus, Lange, Florian, Lee cunningham, Julia, Lees, Jeffrey, Leung, Tak yan, Levy, Neil, Lockwood, Patricia l., Longoni, Chiara, López ortega, Alberto, Loschelder, David D., Lu, Jackson G., Luo, Yu, Luomba, Joseph, Lutz, Annika E., Majer, Johann M., Markowitz, Ezra, Marsh, Abigail A., Mascarenhas, Karen Louise, Mbilingi, Bwambale, Mbungu, Winfred, Mchugh, Cillian, Meijers, Marijn H. C., Mercier, Hugo, Mhagama, Fenant laurent, Michalakis, Katerina, Mikus, Nace, Milliron, Sarah, Mitkidis, Panagiotis, Monge-Rodríguez, Fredy s., Mora, Youri l., Moreau, David, Motoki, Kosuke, Moyano, Manuel, Mus, Mathilde, Navajas, Joaquin, Nguyen, Tam Luong, Nguyen, Dung Minh, Nguyen, Trieu, Niemi, Laura, Nijssen, Sari R. R., Nilsonne, Gustav, Nitschke, Jonas P., Nockur, Laila, Okura, Ritah, Öner, Sezin, Özdoğru, Asil ali, Palumbo, Helena, Panagopoulos, Costas, Panasiti, Maria serena, Pärnamets, Philip, Paruzel-Czachura, Mariola, Pavlov, Yuri g., Payán-Gómez, César, Pearson, Adam r., Pereira da costa, Leonor, Petrowsky, Hannes m., Pfattheicher, Stefan, Pham, Nhat Tan, Ponizovskiy, Vladimir, Pretus, Clara, Rêgo, Gabriel g., Reimann, Ritsaart, Rhoads, Shawn A., Riano-Moreno, Julian, Richter, Isabell, Röer, Jan philipp, Rosa-Sullivan, Jahred, Ross, Robert m., Sabherwal, Anandita, Saito, Toshiki, Sarrasin, Oriane, Say, Nicolas, Schmid, Katharina, Schmitt, Michael T., Schoenegger, Philipp, Scholz, Christin, Schug, Mariah g., Schulreich, Stefan, Shreedhar, Ganga, Shuman, Eric, Sivan, Smadar, Sjåstad, Hallgeir, Soliman, Meikel, Soud, Katia, Spampatti, Tobia, Sparkman, Gregg, Spasovski, Ognen, Stanley, Samantha K., Stern, Jessica A., Strahm, Noel, Suko, Yasushi, Sul, Sunhae, Syropoulos, Stylianos, Taylor, Neil C., Tedaldi, Elisa, Tinghög, Gustav, Huynh, Luu duc toan, Travaglino, Giovanni antonio, Tsakiris, Manos, Tüter, İlayda, Tyrala, Michael, Uluğ, Özden melis, Urbanek, Arkadiusz, Valko, Danila, Van der linden, Sander, Van schie, Kevin, Van stekelenburg, Aart, Vanags, Edmunds, Västfjäll, Daniel, Vesely, Stepan, Vintr, Jáchym, Vranka, Marek, Wanguche, Patrick otuo, Willer, Robb, Wojcik, Adrian dominik, Xu, Rachel, Yadav, Anjali, Zawisza, Magdalena, Zhao, Xian, Zhao, Jiaying, Żuk, Dawid, Van bavel, Jay j., Vlasceanu, Madalina, Doell, Kimberly C., Bak-Coleman, Joseph b., Todorova, Boryana, Berkebile-Weinberg, Michael M., Grayson, Samantha j., Patel, Yash, Goldwert, Danielle, Pei, Yifei, Chakroff, Alek, Pronizius, Ekaterina, Van den broek, Karlijn l., Vlasceanu, Denisa, Constantino, Sara, Morais, Michael J., Schumann, Philipp, Rathje, Steve, Fang, Ke, Aglioti, Salvatore maria, Alfano, Mark, Alvarado-Yepez, Andy J., Andersen, Angélica, Anseel, Frederik, Apps, Matthew A. J., Asadli, Chillar, Awuor, Fonda Jane, Azevedo, Flavio, Basaglia, Piero, Bélanger, Jocelyn J., Berger, Sebastian, Bertin, Paul, Białek, Michał, Bialobrzeska, Olga, Blaya-Burgo, Michelle, Bleize, Daniëlle N. M., Bø, Simen, Boecker, Lea, Boggio, Paulo S., Borau, Sylvie, Bos, Björn, Bouguettaya, Ayoub, Brauer, Markus, Brick, Cameron, Brik, Tymofii, Briker, Roman, Brosch, Tobias, Buchel, Ondrej, Buonauro, Daniel, Butalia, Radhika, Carvacho, Héctor, Chamberlain, Sarah A. E., Chan, Hang-Yee, Chow, Dawn, Chung, Dongil, Cian, Luca, Cohen-Eick, Noa, Contreras-Huerta, Luis sebastian, Contu, Davide, Cristea, Vladimir, Cutler, Jo, D'ottone, Silvana, De keersmaecker, Jonas, Delcourt, Sarah, Delouvée, Sylvain, Diel, Kathi, Douglas, Benjamin d., Drupp, Moritz a., Dubey, Shreya, Ekmanis, Jānis, Elbaek, Christian t., Elsherif, Mahmoud, Engelhard, Iris m., Escher, Yannik a., Etienne, Tom W., Farage, Laura, Farias, Ana Rita, Feuerriegel, Stefan, Findor, Andrej, Freira, Lucia, Friese, Malte, Gains, Neil philip, Gallyamova, Albina, Geiger, Sandra j., Genschow, Oliver, Gjoneska, Biljana, Gkinopoulos, Theofilos, Goldberg, Beth, Goldenberg, Amit, Gradidge, Sarah, Grassini, Simone, Gray, Kurt, Grelle, Sonja, Griffin, Siobhán m., Grigoryan, Lusine, Grigoryan, Ani, Grigoryev, Dmitry, Gruber, June, Guilaran, Johnrev, Hadar, Britt, Hahnel, Ulf j.j., Halperin, Eran, Harvey, Annelie j., Haugestad, Christian a. p., Herman, Aleksandra M., Hershfield, Hal E., Himichi, Toshiyuki, Hine, Donald W., Hofmann, Wilhelm, Howe, Lauren, Huaman-Chulluncuy, Enma t., Huang, Guanxiong, Ishii, Tatsunori, Ito, Ayahito, Jia, Fanli, Jost, John T., Jovanović, Veljko, Jurgiel, Dominika, Kácha, Ondřej, Kankaanpää, Reeta, Kantorowicz, Jaroslaw, Kantorowicz-Reznichenko, Elena, Kaplan mintz, Keren, Kaya, Ilker, Kaya, Ozgur, Khachatryan, Narine, Klas, Anna, Klein, Colin, Klöckner, Christian a., Koppel, Lina, Kosachenko, Alexandra i., Kothe, Emily J., Krebs, Ruth, Krosch, Amy R., Krouwel, Andre P. M., Kyrychenko, Yara, Lagomarsino, Maria, Lamm, Claus, Lange, Florian, Lee cunningham, Julia, Lees, Jeffrey, Leung, Tak yan, Levy, Neil, Lockwood, Patricia l., Longoni, Chiara, López ortega, Alberto, Loschelder, David D., Lu, Jackson G., Luo, Yu, Luomba, Joseph, Lutz, Annika E., Majer, Johann M., Markowitz, Ezra, Marsh, Abigail A., Mascarenhas, Karen Louise, Mbilingi, Bwambale, Mbungu, Winfred, Mchugh, Cillian, Meijers, Marijn H. C., Mercier, Hugo, Mhagama, Fenant laurent, Michalakis, Katerina, Mikus, Nace, Milliron, Sarah, Mitkidis, Panagiotis, Monge-Rodríguez, Fredy s., Mora, Youri l., Moreau, David, Motoki, Kosuke, Moyano, Manuel, Mus, Mathilde, Navajas, Joaquin, Nguyen, Tam Luong, Nguyen, Dung Minh, Nguyen, Trieu, Niemi, Laura, Nijssen, Sari R. R., Nilsonne, Gustav, Nitschke, Jonas P., Nockur, Laila, Okura, Ritah, Öner, Sezin, Özdoğru, Asil ali, Palumbo, Helena, Panagopoulos, Costas, Panasiti, Maria serena, Pärnamets, Philip, Paruzel-Czachura, Mariola, Pavlov, Yuri g., Payán-Gómez, César, Pearson, Adam r., Pereira da costa, Leonor, Petrowsky, Hannes m., Pfattheicher, Stefan, Pham, Nhat Tan, Ponizovskiy, Vladimir, Pretus, Clara, Rêgo, Gabriel g., Reimann, Ritsaart, Rhoads, Shawn A., Riano-Moreno, Julian, Richter, Isabell, Röer, Jan philipp, Rosa-Sullivan, Jahred, Ross, Robert m., Sabherwal, Anandita, Saito, Toshiki, Sarrasin, Oriane, Say, Nicolas, Schmid, Katharina, Schmitt, Michael T., Schoenegger, Philipp, Scholz, Christin, Schug, Mariah g., Schulreich, Stefan, Shreedhar, Ganga, Shuman, Eric, Sivan, Smadar, Sjåstad, Hallgeir, Soliman, Meikel, Soud, Katia, Spampatti, Tobia, Sparkman, Gregg, Spasovski, Ognen, Stanley, Samantha K., Stern, Jessica A., Strahm, Noel, Suko, Yasushi, Sul, Sunhae, Syropoulos, Stylianos, Taylor, Neil C., Tedaldi, Elisa, Tinghög, Gustav, Huynh, Luu duc toan, Travaglino, Giovanni antonio, Tsakiris, Manos, Tüter, İlayda, Tyrala, Michael, Uluğ, Özden melis, Urbanek, Arkadiusz, Valko, Danila, Van der linden, Sander, Van schie, Kevin, Van stekelenburg, Aart, Vanags, Edmunds, Västfjäll, Daniel, Vesely, Stepan, Vintr, Jáchym, Vranka, Marek, Wanguche, Patrick otuo, Willer, Robb, Wojcik, Adrian dominik, Xu, Rachel, Yadav, Anjali, Zawisza, Magdalena, Zhao, Xian, Zhao, Jiaying, Żuk, Dawid, and Van bavel, Jay j.

Abstract

Effectively reducing climate change requires marked, global behavior change. However, it is unclear which strategies are most likely to motivate people to change their climate beliefs and behaviors. Here, we tested 11 expert-crowdsourced interventions on four climate mitigation outcomes: beliefs, policy support, information sharing intention, and an effortful tree-planting behavioral task. Across 59,440 participants from 63 countries, the interventions’ effectiveness was small, largely limited to nonclimate skeptics, and differed across outcomes: Beliefs were strengthened mostly by decreasing psychological distance (by 2.3%), policy support by writing a letter to a future-generation member (2.6%), information sharing by negative emotion induction (12.1%), and no intervention increased the more effortful behavior—several interventions even reduced tree planting. Last, the effects of each intervention differed depending on people’s initial climate beliefs. These findings suggest that the impact of behavioral climate interventions varies across audiences and target behaviors.

168. Mental health literacy for social phobia in Ghana: Investigation of gender stereotypes and previous experience for recognition rates and prejudice.

Author

Adu, Peter, Jurcik, Tomas, Demah, Emmanuel, Korang, Patrick T, and Grigoryev, Dmitry

Subjects
*SEXISM, *SELF-evaluation, *MENTAL health, *PREJUDICES, *HEALTH literacy, *SOCIAL anxiety, *STEREOTYPES, *GHANAIANS, *RESEARCH funding, *CASE studies, *QUESTIONNAIRES
Abstract

Background: Mental health literacy (MHL) research has been of substantial interest internationally. Nevertheless, the interplay between beliefs, attitudes, previous experience with mental disorders, and knowledge of Ghanaians on specific mental disorders remains to be understood. The present study explored the interconnectedness between gender stereotypes, prejudice, previous experience with social phobia, and MHL among the general population in Ghana. Method: Six hundred and one Ghanaians were recruited for an online experimental study design using a survey approach for data gathering. Respondents were randomly assigned to one of the two conditions (i.e., male and female vignettes) depicting symptoms of social phobia for a hypothetical person. Participants further completed self-reported measures including gender stereotypes (based on Ambivalent Sexism Inventory) and prejudice. Results: Results revealed a 15.5% recognition rate for social phobia. Recognition rates of social phobia did not differ by the experimental condition or by the gender of participants. However, personal experience of social phobia was positively related to an increased likelihood of correctly labeling social phobia among men in the female vignette condition, whereas correct recognition of social phobia was negatively related to prejudice among women in the male vignette condition. In the male vignette condition, men with more hostile sexism attitudes toward men exhibited more prejudice toward their hypothetical male counterpart. In contrast, women with hostile sexism attitudes toward men exhibited less prejudice, but greater benevolent sexism attitudes toward men was associated with more prejudice toward the hypothetical male in the vignette. Conclusion: Findings from the current study emphasize the role of the cultural milieu in shaping effective mental health interventions. The results also have implications for promoting MHL to reduce prejudice in Ghana and other developing countries in the region. [ABSTRACT FROM AUTHOR]

Published
2024
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169. COVID‐19 cases correlate with greater acceptance coping in flexible cultures: A cross‐cultural study in 26 countries.

Author

Zhou, Xiaoyu, English, Alexander Scott, Kulich, Steve J., Zheng, Lu, Alves, Tales, Aquino, Sibele D., Batić Očovaj, Sanja, Belen, Hacer, Biddle, Ashley, Boonroungrut, Chinun, Campos, Adolfo Fabricio Licoa, Castro, Rita, Chettiar, Cicilia, Chobthamkit, Phatthanakit, Cowden, Richard G., Dubrov, Dmitrii, F. Falavarjani, Mehrdad, Farid, Tahir, Geeraert, Nicolas, and Grigoryev, Dmitry

Subjects
*COVID-19 pandemic, *CROSS-cultural studies
Abstract

The current study examines whether the prevalence of COVID‐19 cases and cultural flexibility correlate to one's use of acceptance coping across 26 cultures. We analyzed data from 7476 participants worldwide at the start of the first outbreak from March 2020 to June 2020. Results showed that cultural flexibility moderated the relationship between COVID‐19 cases and individuals' acceptance coping strategies. Specifically, for cultures with high flexibility, COVID‐19 cases correlated with more acceptance coping; for cultures with low flexibility, COVID‐19 cases correlated with less acceptance coping. This result demonstrates how participants from flexible cultures can coexist with the realistic challenges and suffering faced during this pandemic. [ABSTRACT FROM AUTHOR]

Published
2024
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170. Exploring Attitudes Toward "Sugar Relationships" Across 87 Countries: A Global Perspective on Exchanges of Resources for Sex and Companionship.

Author

Meskó, Norbert, Kowal, Marta, Láng, András, Kocsor, Ferenc, Bandi, Szabolcs A., Putz, Adam, Sorokowski, Piotr, Frederick, David A., García, Felipe E., Aguilar, Leonardo A., Studzinska, Anna, Tan, Chee-Seng, Gjoneska, Biljana, Milfont, Taciano L., Topcu Bulut, Merve, Grigoryev, Dmitry, Aavik, Toivo, Boussena, Mahmoud, Mattiassi, Alan D. A., and Afhami, Reza

Subjects
*HUMAN sexuality, *FELLOWSHIP, *INTERPERSONAL relations, *FAVORITISM (Personnel management), *GENDER differences (Psychology), *GENDER role
Abstract

The current study investigates attitudes toward one form of sex for resources: the so-called sugar relationships, which often involve exchanges of resources for sex and/or companionship. The present study examined associations among attitudes toward sugar relationships and relevant variables (e.g., sex, sociosexuality, gender inequality, parasitic exposure) in 69,924 participants across 87 countries. Two self-report measures of Acceptance of Sugar Relationships (ASR) developed for younger companion providers (ASR-YWMS) and older resource providers (ASR-OMWS) were translated into 37 languages. We tested cross-sex and cross-linguistic construct equivalence, cross-cultural invariance in sex differences, and the importance of the hypothetical predictors of ASR. Both measures showed adequate psychometric properties in all languages (except the Persian version of ASR-YWMS). Results partially supported our hypotheses and were consistent with previous theoretical considerations and empirical evidence on human mating. For example, at the individual level, sociosexual orientation, traditional gender roles, and pathogen prevalence were significant predictors of both ASR-YWMS and ASR-OMWS. At the country level, gender inequality and parasite stress positively predicted the ASR-YWMS. However, being a woman negatively predicted the ASR-OMWS, but positively predicted the ASR-YWMS. At country-level, ingroup favoritism and parasite stress positively predicted the ASR-OMWS. Furthermore, significant cross-subregional differences were found in the openness to sugar relationships (both ASR-YWMS and ASR-OMWS scores) across subregions. Finally, significant differences were found between ASR-YWMS and ASR-OMWS when compared in each subregion. The ASR-YWMS was significantly higher than the ASR-OMWS in all subregions, except for Northern Africa and Western Asia. [ABSTRACT FROM AUTHOR]

Published
2024
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171. Down-regulation of placental neuropilin-1 in fetal growth restriction.

Author

Maulik, Dev, De, Alok, Ragolia, Louis, Evans, Jodi, Grigoryev, Dmitry, Lankachandra, Kamani, Mundy, David, Muscat, Jolene, Gerkovich, Mary M., and Ye, Shui Qing

Subjects
NEUROPILINS, PREGNANCY proteins, FETAL growth retardation, UMBILICAL arteries, BIOMARKERS, DNA microarrays, RNA metabolism, DOPPLER ultrasonography, BIOCHEMISTRY, BIRTH size, BLOOD circulation, CELL receptors, DIASTOLE (Cardiac cycle), FETAL ultrasonic imaging, GENES, IMMUNOHISTOCHEMISTRY, LONGITUDINAL method, PHENOMENOLOGY, NEOVASCULARIZATION, PLACENTA, POLYMERASE chain reaction, WESTERN immunoblotting, CASE-control method, REVERSE transcriptase polymerase chain reaction, OLIGONUCLEOTIDE arrays, GENE expression profiling
Abstract

Background: Fetal growth restriction (FGR) is associated with adverse outcomes extending from fetal to adult life, and thus, constitutes a major health care challenge. Fetuses with progressive growth restriction show increasing impedance in the umbilical artery flow, which may become absent during end-diastole. Absent end-diastolic flow (AEDF) is associated with adverse perinatal outcomes including stillbirths and perinatal asphyxia. Placentas from such pregnancies demonstrate deficient fetoplacental vascular branching. Current evidence, moreover, indicates an antiangiogenic state in maternal circulation in several pregnancy complications including preeclampsia, small-for-gestational-age births, fetal death, and preterm labor. The angiogenic mediators in maternal circulation are predominantly of placental origin. Information, however, on the role of specific proangiogenic and antiangiogenic mechanisms operating at the placental level remains limited. Elucidation of these placenta-specific angiogenic mechanisms will not only extend our understanding of the causal pathway for restricted fetal growth but may also lead to the development of biomarkers that may allow early recognition of FGR.Objective: We sought to test the hypothesis that fetoplacental angiogenic gene expression is altered in pregnancies complicated with FGR and umbilical artery Doppler AEDF.Study Design: Placental samples were collected from FGR pregnancies complicated with umbilical artery Doppler AEDF (study group, n = 7), and from uncomplicated pregnancies (control group, n = 7), all delivered by cesarean during the last trimester of pregnancy. Angiogenic oligonucleotide microarray analysis was performed and was corroborated by quantitative real-time polymerase chain reaction, Western blot analysis, and immunohistochemistry. The Student t test with Bonferroni correction was used with P < .05 considered statistically significant. Independent groups t test was used to analyze the immunostain intensity scores with a P < .05 considered statistically significant.Results: Our microarray results showed that among several differentially expressed angiogenic genes in the growth-restricted group, only the down-regulation of neuropilin (NRP)-1 was most significant (P < .0007). Quantitative real-time polymerase chain reaction confirmed a significantly lower NRP-1 gene expression in the FGR group than in the control group (mean ± SD (ˆ)cycle threshold: 0.624 ± 0.55 and 1.325 ± 0.84, respectively, P = .04). Western blot validated significantly lower NRP-1 protein expression in the FGR group than in the control group (mean ± SD NRP-1/β-actin ratio: 0.13 ± 0.04 and 0.34 ± 0.05, respectively, P < .001). Finally, immunohistochemistry of placental villi further corroborated a significantly decreased expression of NRP-1 in the FGR group (P = .006).Conclusion: The study demonstrated significant down-regulation of placental NRP-1 expression in FGR pregnancies complicated with AEDF in umbilical artery. As NRP-1 is known to promote sprouting angiogenesis, its down-regulation may be involved in the deficient vascular branching observed in FGR placentas suggesting the presence of an antiangiogenic state. Further studies may elucidate such a causal role and may lead to the development of novel diagnostic and therapeutic tools. [ABSTRACT FROM AUTHOR]

Published
2016
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172. Evaluating the integration hypothesis: A meta‐analysis of the ICSEY project data using two new methods.

Author

Abu‐Rayya, Hisham M., Berry, John W., Sam, David L., and Grigoryev, Dmitry

Subjects
*IMMIGRANTS, *META-analysis, *ACCULTURATION, *DISCRIMINATION (Sociology), *SOCIAL adjustment, *FAMILY separation policy, 2018-2021, *SOCIAL isolation, *PSYCHOLOGICAL adaptation, *SOCIAL integration, *SOCIAL psychology
Abstract

The Integration Hypothesis states that acculturating migrants who adopt the integration strategy (i.e. being doubly engaged, in both their heritage culture and in the larger national society) will have better psychological and socio‐cultural adaptation than those who adopt any other strategy (Assimilation, Separation or Marginalization). This hypothesis was supported in the original evaluation of the ICSEY project data, using the mean adaptation scores for individuals in the four acculturation clusters. This conclusion was further supported by an analysis that used scores that were derived from the two underlying dimensions. This paper further evaluates this hypothesis meta‐analytically using two new methods: Cultural Involvement and Cultural Preference; and Euclidean Distance. The results showed that these two methods provided support for the integration hypothesis, for both psychological adaptation and socio‐cultural adaptation. The pattern of relationships was stronger for positive than for negative indicators of adaptation. Theoretical and practical implications of the results are discussed. [ABSTRACT FROM AUTHOR]

Published
2023
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173. Warmth and competence perceptions of key protagonists are associated with containment measures during the COVID-19 pandemic: Evidence from 35 countries.

Author

Friehs, Maria-Therese, Kotzur, Patrick F., Kraus, Christine, Schemmerling, Moritz, Herzig, Jessica A., Stanciu, Adrian, Dilly, Sebastian, Hellert, Lisa, Hübner, Doreen, Rückwardt, Anja, Ulizcay, Veruschka, Christ, Oliver, Brambilla, Marco, De keersmaecker, Jonas, Durante, Federica, Gale, Jessica, Grigoryev, Dmitry, Igou, Eric R., Javakhishvili, Nino, and Kienmoser, Doris

Subjects
*COVID-19 pandemic, *PROTEST movements, *CONFIRMATORY factor analysis, *SOCIAL perception, *HEADS of state
Abstract

It is crucial to understand why people comply with measures to contain viruses and their effects during pandemics. We provide evidence from 35 countries (Ntotal = 12,553) from 6 continents during the COVID-19 pandemic (between 2021 and 2022) obtained via cross-sectional surveys that the social perception of key protagonists on two basic dimensions—warmth and competence—plays a crucial role in shaping pandemic-related behaviors. Firstly, when asked in an open question format, heads of state, physicians, and protest movements were universally identified as key protagonists across countries. Secondly, multiple-group confirmatory factor analyses revealed that warmth and competence perceptions of these and other protagonists differed significantly within and between countries. Thirdly, internal meta-analyses showed that warmth and competence perceptions of heads of state, physicians, and protest movements were associated with support and opposition intentions, containment and prevention behaviors, as well as vaccination uptake. Our results have important implications for designing effective interventions to motivate desirable health outcomes and coping with future health crises and other global challenges. [ABSTRACT FROM AUTHOR]

Published
2022
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174. Contextual factors predicting compliance behavior during the COVID-19 pandemic: A machine learning analysis on survey data from 16 countries.

Author

Hajdu, Nandor, Schmidt, Kathleen, Acs, Gergely, Röer, Jan P., Mirisola, Alberto, Giammusso, Isabella, Arriaga, Patrícia, Ribeiro, Rafael, Dubrov, Dmitrii, Grigoryev, Dmitry, Arinze, Nwadiogo C., Voracek, Martin, Stieger, Stefan, Adamkovic, Matus, Elsherif, Mahmoud, Kern, Bettina M. J., Barzykowski, Krystian, Ilczuk, Ewa, Martončik, Marcel, and Ropovik, Ivan

Subjects
*COVID-19 pandemic, *MACHINE learning, *PUBLIC health officers, *INFECTIOUS disease transmission, *DATA analysis
Abstract

Voluntary isolation is one of the most effective methods for individuals to help prevent the transmission of diseases such as COVID-19. Understanding why people leave their homes when advised not to do so and identifying what contextual factors predict this non-compliant behavior is essential for policymakers and public health officials. To provide insight on these factors, we collected data from 42,169 individuals across 16 countries. Participants responded to items inquiring about their socio-cultural environment, such as the adherence of fellow citizens, as well as their mental states, such as their level of loneliness and boredom. We trained random forest models to predict whether someone had left their home during a one week period during which they were asked to voluntarily isolate themselves. The analyses indicated that overall, an increase in the feeling of being caged leads to an increased probability of leaving home. In addition, an increased feeling of responsibility and an increased fear of getting infected decreased the probability of leaving home. The models predicted compliance behavior with between 54% and 91% accuracy within each country's sample. In addition, we modeled factors leading to risky behavior in the pandemic context. We observed an increased probability of visiting risky places as both the anticipated number of people and the importance of the activity increased. Conversely, the probability of visiting risky places increased as the perceived putative effectiveness of social distancing decreased. The variance explained in our models predicting risk ranged from <.01 to.54 by country. Together, our findings can inform behavioral interventions to increase adherence to lockdown recommendations in pandemic conditions. [ABSTRACT FROM AUTHOR]

Published
2022
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175. More Similarity if Different, More Difference if Similar: Assimilation, Colorblindness, Multiculturalism, Polyculturalism, and Generalized and Specific Negative Intergroup Bias.

Author

Batkhina, Anastasia, Berry, John W., Jurcik, Tomas, Dubrov, Dmitrii, and Grigoryev, Dmitry

Subjects
*MULTICULTURALISM, *IMPLICIT bias, *INTERGROUP relations, *ETHNIC groups, *ANTISEMITISM
Abstract

The creation of a social climate where all ethnic groups can harmoniously coexist is a central challenge for many countries today. Should we emphasize similarities and common ground or, conversely, recognize that there are important differences between groups? The current study examined relations between diversity ideologies (assimilation, colorblindness, multiculturalism, polyculturalism) and generalized and specific intergroup bias (against Chechens, Belarusians, Uzbeks, Chinese, and Jews and Muslims) among ethnic Russians (N = 701). In Study 1, colorblindness (ignoring differences) and polyculturalism (emphasizing interconnectivity) were associated with lower generalized intergroup bias and lower bias against Chechens, Uzbeks, and Chinese, but not Belarusians. Bias against Belarusians was lower among those who endorsed multiculturalism (emphasizing differences). In Study 2, multiculturalism was associated with higher implicit bias when the target was a Chechen but in general more proximal variables (positive or negative contact experience and perceived group similarity) were more robust predictors of intergroup bias than diversity ideologies. In Study 3, colorblindness and polyculturalism were related to lower levels of fearful attitudes against Muslims. Colorblindness was also associated with lower levels of Antisemitism in contrast to multiculturalism that had an opposite association. We place these results in the context of cultural distance and existing cultural stereotypes about different groups among the majority of Russians. The strengths and weaknesses of each diversity ideology for the mainstream cultural group are discussed. The results of the current study suggest that the most fruitful strategy for mainstream cultural groups for maintaining harmonious intergroup relations in diverse societies might be that of optimal distinctiveness. [ABSTRACT FROM AUTHOR]

Published
2022
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176. The Strategies of Parental Involvement in Adolescents' Education and Extracurricular Activities.

Author

Goshin, Mikhail, Dubrov, Dmitrii, Kosaretsky, Sergey, and Grigoryev, Dmitry

Subjects
*PARENT participation in education, *STUDENT activities, *LEISURE, *MIDDLE school students, *PARENT-child relationships, *HIGH school students
Abstract

Different parental strategies in education are bound to produce various effects: not all of these strategies are equally productive in their application. At the same time, the impact of parental involvement in general education on their children's extracurricular activities has not been thoroughly studied. This article attempts to fill this gap by analyzing the relationship between strategies of parental involvement in education and adolescents' participation in extracurricular activities. The data source for this study were parents whose children attend general education institutions (N = 3,887; Mage of children = 12.4, SD = 3.1; 55.6% female). A latent class analysis identified three categories of parental participation in education: "Intrusive", "Supervisory", and "Detached". Each category showed different patterns of involvement from primary to high school, distinguished by the type of extracurricular participation encouraged by parents. In primary school, children of "Intrusive" parents attended the highest number of extracurricular activities. In secondary school, they attended fewer activities compared to the children of "Supervisory" parents. Children of "Supervisory" parents often chose to participate in activities on their own, and continued to attend the selected activity, or change activity on their own initiative. The children of "Detached" parents were less involved in extracurricular activities in primary school. In some cases, they chose their own extracurricular activities as they grew older. The study demonstrates that parental involvement is related to adolescents' participation in extracurricular activities. Parents' strategies should be considered instrumental as they produce a variety of different outcomes, depending upon the adolescents' age and type of activities. The identified strategies may serve as a basis for recommendations for development of parental competencies, consultations, and family education. [ABSTRACT FROM AUTHOR]

Published
2021
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177. Author Correction: Warmth and competence perceptions of key protagonists are associated with containment measures during the COVID-19 pandemic: Evidence from 35 countries.

Author

Friehs, Maria-Therese, Kotzur, Patrick F., Kraus, Christine, Schemmerling, Moritz, Herzig, Jessica A., Stanciu, Adrian, Dilly, Sebastian, Hellert, Lisa, Hübner, Doreen, Rückwardt, Anja, Ulizcay, Veruschka, Christ, Oliver, Brambilla, Marco, De keersmaecker, Jonas, Durante, Federica, Gale, Jessica, Grigoryev, Dmitry, Igou, Eric R., Javakhishvili, Nino, and Kienmoser, Doris

Subjects
*COVID-19 pandemic, *COUNTRIES
Abstract

Correction to: I Scientific Reports i https://doi.org/10.1038/s41598-022-25228-9, published online 08 December 2022 The original version of this Article contained an error in Affiliation 27, which was incorrectly given as "University of Nicosia, Nicosia, Cyprus". The correct Affiliation is listed below: University of Cyprus, Nicosia, Cyprus. [Extracted from the article]

Published
2023
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178. A worldwide test of the predictive validity of ideal partner preference matching.

Author

Eastwick PW, Sparks J, Finkel EJ, Meza EM, Adamkovič M, Adu P, Ai T, Akintola AA, Al-Shawaf L, Apriliawati D, Arriaga P, Aubert-Teillaud B, Baník G, Barzykowski K, Batres C, Baucom KJ, Beaulieu EZ, Behnke M, Butcher N, Charles DY, Chen JM, Cheon JE, Chittham P, Chwiłkowska P, Cong CW, Copping LT, Corral-Frias NS, Ćubela Adorić V, Dizon M, Du H, Ehinmowo MI, Escribano DA, Espinosa NM, Expósito F, Feldman G, Freitag R, Frias Armenta M, Gallyamova A, Gillath O, Gjoneska B, Gkinopoulos T, Grafe F, Grigoryev D, Groyecka-Bernard A, Gunaydin G, Ilustrisimo R, Impett E, Kačmár P, Kim YH, Kocur M, Kowal M, Krishna M, Labor PD, Lu JG, Lucas MY, Małecki WP, Malinakova K, Meißner S, Meier Z, Misiak M, Muise A, Novak L, O J, Özdoğru AA, Park HG, Paruzel M, Pavlović Z, Püski M, Ribeiro G, Roberts SC, Röer JP, Ropovik I, Ross RM, Sakman E, Salvador CE, Selcuk E, Skakoon-Sparling S, Sorokowska A, Sorokowski P, Spasovski O, Stanton SCE, Stewart SLK, Swami V, Szaszi B, Takashima K, Tavel P, Tejada J, Tu E, Tuominen J, Vaidis D, Vally Z, Vaughn LA, Villanueva-Moya L, Wisnuwardhani D, Yamada Y, Yonemitsu F, Žídková R, Živná K, and Coles NA

Abstract

Ideal partner preferences (i.e., ratings of the desirability of attributes like attractiveness or intelligence) are the source of numerous foundational findings in the interdisciplinary literature on human mating. Recently, research on the predictive validity of ideal partner preference matching (i.e., Do people positively evaluate partners who match vs. mismatch their ideals?) has become mired in several problems. First, articles exhibit discrepant analytic and reporting practices. Second, different findings emerge across laboratories worldwide, perhaps because they sample different relationship contexts and/or populations. This registered report-partnered with the Psychological Science Accelerator-uses a highly powered design ( N = 10,358) across 43 countries and 22 languages to estimate preference-matching effect sizes. The most rigorous tests revealed significant preference-matching effects in the whole sample and for partnered and single participants separately. The "corrected pattern metric" that collapses across 35 traits revealed a zero-order effect of β = .19 and an effect of β = .11 when included alongside a normative preference-matching metric. Specific traits in the "level metric" (interaction) tests revealed very small (average β = .04) effects. Effect sizes were similar for partnered participants who reported ideals before entering a relationship, and there was no consistent evidence that individual differences moderated any effects. Comparisons between stated and revealed preferences shed light on gender differences and similarities: For attractiveness, men's and (especially) women's stated preferences underestimated revealed preferences (i.e., they thought attractiveness was less important than it actually was). For earning potential, men's stated preferences underestimated-and women's stated preferences overestimated-revealed preferences. Implications for the literature on human mating are discussed. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Published
2024
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179. The International Climate Psychology Collaboration: Climate change-related data collected from 63 countries.

Author

Doell KC, Todorova B, Vlasceanu M, Bak Coleman JB, Pronizius E, Schumann P, Azevedo F, Patel Y, Berkebile-Wineberg MM, Brick C, Lange F, Grayson SJ, Pei Y, Chakroff A, van den Broek KL, Lamm C, Vlasceanu D, Constantino SM, Rathje S, Goldwert D, Fang K, Aglioti SM, Alfano M, Alvarado-Yepez AJ, Andersen A, Anseel F, Apps MAJ, Asadli C, Awuor FJ, Basaglia P, Bélanger JJ, Berger S, Bertin P, Białek M, Bialobrzeska O, Blaya-Burgo M, Bleize DNM, Bø S, Boecker L, Boggio PS, Borau S, Borau S, Bos B, Bouguettaya A, Brauer M, Brik T, Briker R, Brosch T, Buchel O, Buonauro D, Butalia R, Carvacho H, Chamberlain SAE, Chan HY, Chow D, Chung D, Cian L, Cohen-Eick N, Contreras-Huerta LS, Contu D, Cristea V, Cutler J, D'Ottone S, De Keersmaecker J, Delcourt S, Delouvée S, Diel K, Douglas BD, Drupp MA, Dubey S, Ekmanis J, Elbaek CT, Elsherif M, Engelhard IM, Escher YA, Etienne TW, Farage L, Farias AR, Feuerriegel S, Findor A, Freira L, Friese M, Gains NP, Gallyamova A, Geiger SJ, Genschow O, Gjoneska B, Gkinopoulos T, Goldberg B, Goldenberg A, Gradidge S, Grassini S, Gray K, Grelle S, Griffin SM, Grigoryan L, Grigoryan A, Grigoryev D, Gruber J, Guilaran J, Hadar B, Hahnel UJJ, Halperin E, Harvey AJ, Haugestad CAP, Herman AM, Hershfield HE, Himichi T, Hine DW, Hofmann W, Howe L, Huaman-Chulluncuy ET, Huang G, Ishii T, Ito A, Jia F, Jost JT, Jovanović V, Jurgiel D, Kácha O, Kankaanpää R, Kantorowicz J, Kantorowicz-Reznichenko E, Mintz KK, Kaya I, Kaya O, Khachatryan N, Klas A, Klein C, Klöckner CA, Koppel L, Kosachenko AI, Kothe EJ, Krebs R, Krosch AR, Krouwel APM, Kyrychenko Y, Lagomarsino M, Cunningham JL, Lees J, Leung TY, Levy N, Lockwood PL, Longoni C, Ortega AL, Loschelder DD, Lu JG, Luo Y, Luomba J, Lutz AE, Majer JM, Markowitz E, Marsh AA, Mascarenhas KL, Mbilingi B, Mbungu W, McHugh C, Meijers MHC, Mercier H, Mhagama FL, Michalaki K, Mikus N, Milliron SG, Mitkidis P, Monge-Rodríguez FS, Mora YL, Morais MJ, Moreau D, Motoki K, Moyano M, Mus M, Navajas J, Nguyen TL, Nguyen DM, Nguyen T, Niemi L, Nijssen SRR, Nilsonne G, Nitschke JP, Nockur L, Okura R, Öner S, Özdoğru AA, Palumbo H, Panagopoulos C, Panasiti MS, Pärnamets P, Paruzel-Czachura M, Pavlov YG, Payán-Gómez C, Pearson AR, da Costa LP, Petrowsky HM, Pfattheicher S, Pham NT, Ponizovskiy V, Pretus C, Rêgo GG, Reimann R, Rhoads SA, Riano-Moreno J, Richter I, Röer JP, Rosa-Sullivan J, Ross RM, Sabherwal A, Saito T, Sarrasin O, Say N, Schmid K, Schmitt MT, Schoenegger P, Scholz C, Schug MG, Schulreich S, Shreedhar G, Shuman E, Sivan S, Sjåstad H, Soliman M, Soud K, Spampatti T, Sparkman G, Spasovski O, Stanley SK, Stern JA, Strahm N, Suko Y, Sul S, Syropoulos S, Taylor NC, Tedaldi E, Tinghög G, Huynh LDT, Travaglino GA, Tsakiris M, Tüter İ, Tyrala M, Uluğ ÖM, Urbanek A, Valko D, van der Linden S, van Schie K, van Stekelenburg A, Vanags E, Västfjäll D, Vesely S, Vintr J, Vranka M, Wanguche PO, Willer R, Wojcik AD, Xu R, Yadav A, Zawisza M, Zhao X, Zhao J, Żuk D, and Van Bavel JJ

Subjects
Humans, Surveys and Questionnaires, Climate Change
Abstract

Climate change is currently one of humanity's greatest threats. To help scholars understand the psychology of climate change, we conducted an online quasi-experimental survey on 59,508 participants from 63 countries (collected between July 2022 and July 2023). In a between-subjects design, we tested 11 interventions designed to promote climate change mitigation across four outcomes: climate change belief, support for climate policies, willingness to share information on social media, and performance on an effortful pro-environmental behavioural task. Participants also reported their demographic information (e.g., age, gender) and several other independent variables (e.g., political orientation, perceptions about the scientific consensus). In the no-intervention control group, we also measured important additional variables, such as environmentalist identity and trust in climate science. We report the collaboration procedure, study design, raw and cleaned data, all survey materials, relevant analysis scripts, and data visualisations. This dataset can be used to further the understanding of psychological, demographic, and national-level factors related to individual-level climate action and how these differ across countries., (© 2024. The Author(s).)

Published
2024
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180. Validation of the Revised Multicultural Ideology Scale (MCI-r) in the UK.

Author

Lefringhausen K, Berry JW, Grigoryev D, and Stogianni M

Subjects
Humans, United Kingdom, Female, Male, Adult, Middle Aged, Reproducibility of Results, Young Adult, Social Interaction, Aged, Adolescent, Cultural Diversity, Psychometrics standards, Psychometrics instrumentation
Abstract

As worldwide migration continues to grow, valid and reliable instruments are needed to assess the psychological processes that influence the successful management of intercultural relations in different sociopolitical contexts. In this study, we test whether the original Multicultural Ideology Scale (MCI) required a revision to remain 'fit for purpose' in the current culturally plural context of the UK (MCI-r). Specifically, six subscales are proposed to underlie the construct of a multicultural ideology: Cultural Maintenance, Equity/Inclusion, Social interaction, Essentialistic Boundaries, Extent of Differences, and Consequences of Diversity. With data from 300 UK nationals, we tested the psychometric properties of the MCI-r using various confirmatory factor analysis techniques to estimate the scale's factor structure followed by convergent and discriminant validity tests. The results indicated that a 4-factor solution (Cultural Maintenance, Equity/Inclusion, Social interaction, and Consequences of Diversity) fitted the data best. All four subscales demonstrated adequate internal consistency as well as convergent and discriminant validity. All four subscales were also negatively correlated with a right-wing political orientation, whilst especially Social Interaction and Consequences of Diversity were positively associated with intergroup contact frequency across domains (work, family and friends and/or acquaintances). Finally, UK participants with personal migratory experiences reported a stronger belief in positive consequences of multiculturalism and more support for Social Interactions between members of different ethnic groups. Overall, findings provide first insights into the applicability of the MCI-r as a reliable and valid tool for the assessment of multiculturalism within the present UK context., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Published
2024
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181. Collective action against corruption in Western and non-Western countries: cross-cultural implications of the Axiological-Identitary Collective Action Model.

Author

Grigoryev D, Gallyamova A, Conway LG 3rd, Zubrod A, Sabucedo JM, Dono M, Batkhina A, and Boehnke K

Abstract

People sometimes protest government corruption, yet our current understanding of why they do so is culturally constrained. Can we separate pancultural factors influencing people's willingness to protest government corruption from factors culturally specific to each socioecological context? Surprisingly little cross-cultural data exist on this important question. To fill this gap, we performed a cross-cultural test of the Axiological-Identitary Collective Action Model (AICAM) regarding the intention to protest against corruption. As a collective action framework, AICAM integrates three classical antecedents of collective action (injustice, efficacy, identity) with axiological variables (ideology and morality). A total sample of 2,316 participants from six countries (Nigeria, Russia, India, Spain, United States, Germany) in a multilevel analysis of AICAM predictions showed that the positive relationship of the intention to protest corruption with moral obligation, system-based anger, and national identification can be considered pancultural. In contrast, the relationships between system justification and perceived efficacy are culturally specific. System justification negatively predicted the intention to participate only in countries with high levels of wealth, while perceived efficacy positively predicted it only in countries perceived as less corrupt. These findings highlight the importance of accounting features of socioecology and separating pancultural from culture-specific effects in understanding collective action., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Grigoryev, Gallyamova, Conway, Zubrod, Sabucedo, Dono, Batkhina and Boehnke.)

Published
2024
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182. Addressing climate change with behavioral science: A global intervention tournament in 63 countries.

Author

Vlasceanu M, Doell KC, Bak-Coleman JB, Todorova B, Berkebile-Weinberg MM, Grayson SJ, Patel Y, Goldwert D, Pei Y, Chakroff A, Pronizius E, van den Broek KL, Vlasceanu D, Constantino S, Morais MJ, Schumann P, Rathje S, Fang K, Aglioti SM, Alfano M, Alvarado-Yepez AJ, Andersen A, Anseel F, Apps MAJ, Asadli C, Awuor FJ, Azevedo F, Basaglia P, Bélanger JJ, Berger S, Bertin P, Białek M, Bialobrzeska O, Blaya-Burgo M, Bleize DNM, Bø S, Boecker L, Boggio PS, Borau S, Bos B, Bouguettaya A, Brauer M, Brick C, Brik T, Briker R, Brosch T, Buchel O, Buonauro D, Butalia R, Carvacho H, Chamberlain SAE, Chan HY, Chow D, Chung D, Cian L, Cohen-Eick N, Contreras-Huerta LS, Contu D, Cristea V, Cutler J, D'Ottone S, De Keersmaecker J, Delcourt S, Delouvée S, Diel K, Douglas BD, Drupp MA, Dubey S, Ekmanis J, Elbaek CT, Elsherif M, Engelhard IM, Escher YA, Etienne TW, Farage L, Farias AR, Feuerriegel S, Findor A, Freira L, Friese M, Gains NP, Gallyamova A, Geiger SJ, Genschow O, Gjoneska B, Gkinopoulos T, Goldberg B, Goldenberg A, Gradidge S, Grassini S, Gray K, Grelle S, Griffin SM, Grigoryan L, Grigoryan A, Grigoryev D, Gruber J, Guilaran J, Hadar B, Hahnel UJJ, Halperin E, Harvey AJ, Haugestad CAP, Herman AM, Hershfield HE, Himichi T, Hine DW, Hofmann W, Howe L, Huaman-Chulluncuy ET, Huang G, Ishii T, Ito A, Jia F, Jost JT, Jovanović V, Jurgiel D, Kácha O, Kankaanpää R, Kantorowicz J, Kantorowicz-Reznichenko E, Kaplan Mintz K, Kaya I, Kaya O, Khachatryan N, Klas A, Klein C, Klöckner CA, Koppel L, Kosachenko AI, Kothe EJ, Krebs R, Krosch AR, Krouwel APM, Kyrychenko Y, Lagomarsino M, Lamm C, Lange F, Lee Cunningham J, Lees J, Leung TY, Levy N, Lockwood PL, Longoni C, López Ortega A, Loschelder DD, Lu JG, Luo Y, Luomba J, Lutz AE, Majer JM, Markowitz E, Marsh AA, Mascarenhas KL, Mbilingi B, Mbungu W, McHugh C, Meijers MHC, Mercier H, Mhagama FL, Michalakis K, Mikus N, Milliron S, Mitkidis P, Monge-Rodríguez FS, Mora YL, Moreau D, Motoki K, Moyano M, Mus M, Navajas J, Nguyen TL, Nguyen DM, Nguyen T, Niemi L, Nijssen SRR, Nilsonne G, Nitschke JP, Nockur L, Okura R, Öner S, Özdoğru AA, Palumbo H, Panagopoulos C, Panasiti MS, Pärnamets P, Paruzel-Czachura M, Pavlov YG, Payán-Gómez C, Pearson AR, Pereira da Costa L, Petrowsky HM, Pfattheicher S, Pham NT, Ponizovskiy V, Pretus C, Rêgo GG, Reimann R, Rhoads SA, Riano-Moreno J, Richter I, Röer JP, Rosa-Sullivan J, Ross RM, Sabherwal A, Saito T, Sarrasin O, Say N, Schmid K, Schmitt MT, Schoenegger P, Scholz C, Schug MG, Schulreich S, Shreedhar G, Shuman E, Sivan S, Sjåstad H, Soliman M, Soud K, Spampatti T, Sparkman G, Spasovski O, Stanley SK, Stern JA, Strahm N, Suko Y, Sul S, Syropoulos S, Taylor NC, Tedaldi E, Tinghög G, Huynh LDT, Travaglino GA, Tsakiris M, Tüter İ, Tyrala M, Uluğ ÖM, Urbanek A, Valko D, van der Linden S, van Schie K, van Stekelenburg A, Vanags E, Västfjäll D, Vesely S, Vintr J, Vranka M, Wanguche PO, Willer R, Wojcik AD, Xu R, Yadav A, Zawisza M, Zhao X, Zhao J, Żuk D, and Van Bavel JJ

Subjects
Humans, Intention, Policy, Climate Change, Behavioral Sciences
Abstract

Effectively reducing climate change requires marked, global behavior change. However, it is unclear which strategies are most likely to motivate people to change their climate beliefs and behaviors. Here, we tested 11 expert-crowdsourced interventions on four climate mitigation outcomes: beliefs, policy support, information sharing intention, and an effortful tree-planting behavioral task. Across 59,440 participants from 63 countries, the interventions' effectiveness was small, largely limited to nonclimate skeptics, and differed across outcomes: Beliefs were strengthened mostly by decreasing psychological distance (by 2.3%), policy support by writing a letter to a future-generation member (2.6%), information sharing by negative emotion induction (12.1%), and no intervention increased the more effortful behavior-several interventions even reduced tree planting. Last, the effects of each intervention differed depending on people's initial climate beliefs. These findings suggest that the impact of behavioral climate interventions varies across audiences and target behaviors.

Published
2024
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183. Basic values as a motivational framework relating individual values with acculturation strategies among Arab immigrants and refugees across different settlement contexts.

Author

Abu-Rayya HM, Berry JW, Lepshokova Z, Alnunu M, and Grigoryev D

Abstract

There is a lack of systematic acculturation research on the motivations underpinning the behavior of migrants, which could explain how they acculturate and adapt to their new country of residence. This paper examines the link between values, using the Schwartz Theory of Basic Human Values, and acculturation strategies among Arab immigrant and refugee groups across different settlement contexts. The results of Study 1 (Arab immigrants; N  = 456) showed, as hypothesized, positive links between strategies and values: the integration strategy with conservation, social focus, self-protection, and self-transcendence values; assimilation with openness to change, personal focus, and growth values; and separation with conservation, social focus, and self-protection. These findings were generally repeated in Study 2 (Syrian refugees; N  = 415) except that integration was not associated with self-transcendence and that assimilation was positively linked to self-enhancement instead of openness to change. Our analyses indicated that acculturation preferences are mainly related to motivational values, rather than to different settlement contexts in both samples; however, assimilation seems to be more associated to context than values among the refugee sample. Implications of the findings to the acculturation literature are discussed., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2023 Abu-Rayya, Berry, Lepshokova, Alnunu and Grigoryev.)

Published
2023
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184. The Psychological Science Accelerator's COVID-19 rapid-response dataset.

Author

Buchanan EM, Lewis SC, Paris B, Forscher PS, Pavlacic JM, Beshears JE, Drexler SM, Gourdon-Kanhukamwe A, Mallik PR, Silan MAA, Miller JK, IJzerman H, Moshontz H, Beaudry JL, Suchow JW, Chartier CR, Coles NA, Sharifian M, Todsen AL, Levitan CA, Azevedo F, Legate N, Heller B, Rothman AJ, Dorison CA, Gill BP, Wang K, Rees VW, Gibbs N, Goldenberg A, Thi Nguyen TV, Gross JJ, Kaminski G, von Bastian CC, Paruzel-Czachura M, Mosannenzadeh F, Azouaghe S, Bran A, Ruiz-Fernandez S, Santos AC, Reggev N, Zickfeld JH, Akkas H, Pantazi M, Ropovik I, Korbmacher M, Arriaga P, Gjoneska B, Warmelink L, Alves SG, de Holanda Coelho GL, Stieger S, Schei V, Hanel PHP, Szaszi B, Fedotov M, Antfolk J, Marcu GM, Schrötter J, Kunst JR, Geiger SJ, Adetula A, Kocalar HE, Kielińska J, Kačmár P, Bokkour A, Galindo-Caballero OJ, Djamai I, Pöntinen SJ, Agesin BE, Jernsäther T, Urooj A, Rachev NR, Koptjevskaja-Tamm M, Kurfalı M, Pit IL, Li R, Çoksan S, Dubrov D, Paltrow TE, Baník G, Korobova T, Studzinska A, Jiang X, Aruta JJBR, Vintr J, Chiu F, Kaliska L, Berkessel JB, Tümer M, Morales-Izquierdo S, Chuan-Peng H, Vezirian K, Rosa AD, Bialobrzeska O, Vasilev MR, Beitner J, Kácha O, Žuro B, Westerlund M, Nedelcheva-Datsova M, Findor A, Krupić D, Kowal M, Askelund AD, Pourafshari R, Đorđević JM, Schmidt ND, Baklanova E, Szala A, Zakharov I, Vranka MA, Ihaya K, Grano C, Cellini N, Białek M, Anton-Boicuk L, Dalgar I, Adıgüzel A, Verharen JPH, Maturan PLG, Kassianos AP, Oliveira R, Čadek M, Adoric VC, Özdoğru AA, Sverdrup TE, Aczel B, Zambrano D, Ahmed A, Tamnes CK, Yamada Y, Volz L, Sunami N, Suter L, Vieira L, Groyecka-Bernard A, Kamburidis JA, Reips UD, Harutyunyan M, Adetula GA, Allred TB, Barzykowski K, Antazo BG, Zsido AN, Šakan DD, Cyrus-Lai W, Ahlgren LP, Hruška M, Vega D, Manunta E, Mokady A, Capizzi M, Martončik M, Say N, Filip K, Vilar R, Staniaszek K, Vdovic M, Adamkovic M, Johannes N, Hajdu N, Cohen N, Overkott C, Krupić D, Hubena B, Nilsonne G, Mioni G, Solorzano CS, Ishii T, Chen Z, Kushnir E, Karaarslan C, Ribeiro RR, Khaoudi A, Kossowska M, Bavolar J, Hoyer K, Roczniewska M, Karababa A, Becker M, Monteiro RP, Kunisato Y, Metin-Orta I, Adamus S, Kozma L, Czarnek G, Domurat A, Štrukelj E, Alvarez DS, Parzuchowski M, Massoni S, Czamanski-Cohen J, Pronizius E, Muchembled F, van Schie K, Saçaklı A, Hristova E, Kuzminska AO, Charyate A, Bijlstra G, Afhami R, Majeed NM, Musser ED, Sirota M, Ross RM, Yeung SK, Papadatou-Pastou M, Foroni F, Almeida IAT, Grigoryev D, Lewis DMG, Holford DL, Janssen SMJ, Tatachari S, Batres C, Olofsson JK, Daches S, Belaus A, Pfuhl G, Corral-Frias NS, Sousa D, Röer JP, Isager PM, Godbersen H, Walczak RB, Van Doren N, Ren D, Gill T, Voracek M, DeBruine LM, Anne M, Očovaj SB, Thomas AG, Arvanitis A, Ostermann T, Wolfe K, Arinze NC, Bundt C, Lamm C, Calin-Jageman RJ, Davis WE, Karekla M, Zorjan S, Jaremka LM, Uttley J, Hricova M, Koehn MA, Kiselnikova N, Bai H, Krafnick AJ, Balci BB, Ballantyne T, Lins S, Vally Z, Esteban-Serna C, Schmidt K, Macapagal PML, Szwed P, Zdybek PM, Moreau D, Collins WM, Joy-Gaba JA, Vilares I, Tran US, Boudesseul J, Albayrak-Aydemir N, Dixson BJW, Perillo JT, Ferreira A, Westgate EC, Aberson CL, Arinze AI, Jaeger B, Butt MM, Silva JR, Storage DS, Janak AP, Jiménez-Leal W, Soto JA, Sorokowska A, McCarthy R, Tullett AM, Frias-Armenta M, Ribeiro MFF, Hartanto A, Forbes PAG, Willis ML, Del Carmen Tejada R M, Torres AJO, Stephen ID, Vaidis DC, de la Rosa-Gómez A, Yu K, Sutherland CAM, Manavalan M, Behzadnia B, Urban J, Baskin E, McFall JP, Ogbonnaya CE, Fu CHY, Rahal RM, Ndukaihe ILG, Hostler TJ, Kappes HB, Sorokowski P, Khosla M, Lazarevic LB, Eudave L, Vilsmeier JK, Luis EO, Muda R, Agadullina E, Cárcamo RA, Reeck C, Anjum G, Venegas MCT, Misiak M, Ryan RM, Nock NL, Travaglino GA, Mensink MC, Feldman G, Wichman AL, Chou W, Ziano I, Seehuus M, Chopik WJ, Kung FYH, Carpentier J, Vaughn LA, Du H, Xiao Q, Lima TJS, Noone C, Onie S, Verbruggen F, Radtke T, and Primbs MA

Subjects
Humans, Adaptation, Psychological, Health Behavior, Pandemics, Surveys and Questionnaires, COVID-19
Abstract

In response to the COVID-19 pandemic, the Psychological Science Accelerator coordinated three large-scale psychological studies to examine the effects of loss-gain framing, cognitive reappraisals, and autonomy framing manipulations on behavioral intentions and affective measures. The data collected (April to October 2020) included specific measures for each experimental study, a general questionnaire examining health prevention behaviors and COVID-19 experience, geographical and cultural context characterization, and demographic information for each participant. Each participant started the study with the same general questions and then was randomized to complete either one longer experiment or two shorter experiments. Data were provided by 73,223 participants with varying completion rates. Participants completed the survey from 111 geopolitical regions in 44 unique languages/dialects. The anonymized dataset described here is provided in both raw and processed formats to facilitate re-use and further analyses. The dataset offers secondary analytic opportunities to explore coping, framing, and self-determination across a diverse, global sample obtained at the onset of the COVID-19 pandemic, which can be merged with other time-sampled or geographic data., (© 2023. The Author(s).)

Published
2023
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185. An Adaptationist Framework to Examine Intergroup Contact.

Author

Berry JW and Grigoryev D

Abstract

Background: Many culturally-plural societies like Canada or Russia seek ways to manage their cultural diversity in order to promote harmony among coexisting groups. The social sciences have long viewed intergroup contact as a beneficial intervention to achieve such harmony., Objective: This paper proposes an adaptationist framework within which to explain how and why intergroup contact contributes to the positive and negative outcomes for individuals who live together in a plural society. We employed this framework in a case study that may serve as an example of the conceptualization and analysis of these issues in international research. Its structural framework included both positive and negative contact and the role of this contact in the distribution of intercultural and psychological adaptation among a large representative sample of the Canadian population., Design: We used a correlational design with a representative sample of Canadians from a survey carried out by Environics in 2019, which was stratified according to the most current population statistics. The total sample was 3,111 persons age 18 and over and included the largest racialised groups in the country., Results: Our main finding was that intergroup contact (both positive and negative) related to both psychological and intercultural adaptation. These findings have implications for improving intercultural relations, especially through the role of positive contact., Conclusion: The experience of negative contact ( e.g., discrimination) in the near term is an important factor in undermining both forms of adaptation. Nonetheless, while intergroup contact can bring both positive and negative experiences during intercultural interactions, it leads to mutual adaptation over time., Competing Interests: The authors declare no conflict of interest., (© Lomonosov Moscow State University, 2022© Russian Psychological Society, 2022.)

Published
2022
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186. In COVID-19 Health Messaging, Loss Framing Increases Anxiety with Little-to-No Concomitant Benefits: Experimental Evidence from 84 Countries.

Author

Dorison CA, Lerner JS, Heller BH, Rothman AJ, Kawachi II, Wang K, Rees VW, Gill BP, Gibbs N, Ebersole CR, Vally Z, Tajchman Z, Zsido AN, Zrimsek M, Chen Z, Ziano I, Gialitaki Z, Ceary CD, Lin Y, Kunisato Y, Yamada Y, Xiao Q, Jiang X, Du X, Yao E, Wilson JP, Cyrus-Lai W, Jimenez-Leal W, Law W, Collins WM, Richard KL, Vranka M, Ankushev V, Schei V, Križanić V, Kadreva VH, Adoric VC, Tran US, Yeung SK, Hassan W, Houston R, Lima TJS, Ostermann T, Frizzo T, Sverdrup TE, House T, Gill T, Fedotov M, Paltrow T, Jernsäther T, Koptjevskaja-Tamm M, Hostler TJ, Ishii T, Szaszi B, Adamus S, Suter L, Habib S, Studzinska A, Stojanovska D, Janssen SMJ, Stieger S, Schulenberg SE, Tatachari S, Azouaghe S, Sorokowski P, Sorokowska A, Song X, Lewis SC, Sinkolova S, Grigoryev D, Drexler SM, Daches S, Geniole SN, Vračar S, Massoni S, Zorjan S, Sarıoğuz E, Izquierdo SM, Alves SG, Pöntinen S, Solas SÁ, Ordoñez-Riaño S, Očovaj SB, Onie S, Lins S, Çoksan S, Sacakli A, Ruiz-Fernández S, Geiger SJ, FatahModares S, Walczak RB, Betlehem R, Vilar R, Cárcamo R, Ross RM, McCarthy R, Ballantyne T, Westgate EC, Afhami R, Ren D, Monteiro RP, Reips UD, Reggev N, Calin-Jageman RJ, Pourafshari R, Oliveira R, Nedelcheva-Datsova M, Rahal RM, Ribeiro RR, Radtke T, Searston R, Habte R, Zdybek P, Chen SC, Maturan PLG, Perillo JT, Isager PM, Kačmár P, Macapagal PM, Szwed P, Hanel PHP, Forbes PAG, Arriaga P, Paris B, Papachristopoulos K, Correa PS, Kácha O, Bernardo M, Campos O, Bravo ON, Galindo-Caballero OJ, Ogbonnaya CE, Bialobrzeska O, Kiselnikova N, Simonovic N, Cohen N, Nock NL, Johannes N, Albayrak-Aydemir N, Say N, Torunsky N, Van Doren N, Sunami N, Rachev NR, Majeed NM, Schmidt ND, Nadif K, Corral-Frías NS, Ouherrou N, Pantazi M, Lucas MY, Vasilev MR, Ortiz MV, Butt MM, Kabir M, Muda R, Tejada Rivera MDCM, Sirota M, Seehuus M, Parzuchowski M, Toro M, Hricova M, Maldonado MA, Marszalek M, Karekla M, Mioni G, Bosma MJ, Westerlund M, Vdovic M, Bialek M, Silan MA, Anne M, Misiak M, Grinberg M, Capizzi M, Espinoza Barría MF, Kurfali MA, Mensink MC, Harutyunyan M, Khosla M, Korbmacher M, Adamkovič M, Ribeiro MFF, Terskova M, Hruška M, Martončik M, Voracek M, Čadek M, Frías-Armenta M, Kowal M, Topor M, Roczniewska M, Oosterlinck M, Kohlová MB, Paruzel-Czachura M, Romanova M, Papadatou-Pastou M, Lund ML, Antoniadi M, Jones MV, Ortiz MS, Manavalan M, Muminov A, Kossowska M, Friedemann M, Wielgus M, Varella MAC, Colloff MF, Bradford M, Vaughn LA, Eudave L, Vieira L, Pineda LMS, Pérez LC, Lazarevic LB, Jaremka LM, Kushnir E, Anton-Boicuk L, de Holanda Coelho GL, Ahlgren L, Levitan CA, Micheli L, Volz L, Stojanovska M, Boucher L, Samojlenko L, Delgado LGJ, Kaliska L, Warmelink L, Rojas-Berscia LM, Yu K, Wachowicz J, Desai K, Barzykowski K, Kozma L, Evans K, Kirgizova K, Agesin BE, Koehn MA, Wolfe K, Korobova T, Klevjer K, van Schie K, Vezirian K, Damnjanović K, Thommesen KK, Schmidt K, Filip K, Grzech K, Hoyer K, Moon K, Rana K, Janjić K, Suchow JW, Kielińska J, Cruz Vásquez JE, Beitner J, Vargas-Nieto JC, Roxas JCT, Taber J, Urriago-Rayo J, Pavlacic JM, Bavolar J, Soto JA, Olofsson JK, Vilsmeier JK, Messerschmidt J, Czamanski-Cohen J, Boudesseul J, Lee JM, Kamburidis J, Zickfeld J, Miranda JF, Verharen JPH, Hristova E, Beshears JE, Đorđević JM, Bosch J, Valentova JV, Antfolk J, Berkessel JB, Schrötter J, Urban J, Röer JP, Norton JO, Silva JR, Pickering JS, Vintr J, Uttley J, Kunst JR, Ndukaihe ILG, Iyer A, Vilares I, Ivanov A, Ropovik I, Sula I, Sarieva I, Metin-Orta I, Prusova I, Pinto I, Bozdoc AI, Almeida IAT, Pit IL, Dalgar I, Zakharov I, Arinze AI, Ihaya K, Stephen ID, Gjoneska B, Brohmer H, Flowe H, Godbersen H, Kocalar HE, Hedgebeth MV, Chuan-Peng H, Sharifian M, Manley H, Akkas H, Hajdu N, Azab H, Kaminski G, Nilsonne G, Anjum G, Travaglino GA, Feldman G, Pfuhl G, Czarnek G, Marcu GM, Hofer G, Banik G, Adetula GA, Bijlstra G, Verbruggen F, Kung FYH, Foroni F, Singer G, Muchembled F, Azevedo F, Mosannenzadeh F, Marinov E, Štrukelj E, Etebari Z, Baskin E, Garcia EOL, Musser E, van Steenkiste IMM, Ahn ER, Pronizius E, Jackson EA, Manunta E, Agadullina E, Šakan D, Dursun P, Dujols O, Dubrov D, Willis M, Tümer M, Beaudry JL, Popović D, Dunleavy D, Djamai I, Krupić D, Vega D, Du H, Mola D, Davis WE, Holford DL, Lewis DMG, Vaidis DC, Ozery DH, Ricaurte DZ, Storage D, Sousa D, Alvarez DS, Rosa AD, Krupić D, Marko D, Moreau D, Reeck C, Correia RC, Whitt CM, Lamm C, Solorzano CS, von Bastian CC, Sutherland CA, Overkott C, Aberson CL, Wang C, Karashiali C, Noone C, Chiu F, Picciocchi C, Karaarslan C, Cellini N, Esteban-Serna C, Reyna C, Batres C, Li R, Grano C, Carpentier J, Tamnes CK, Fu CHY, Ishkhanyan B, Bylinina L, Jaeger B, Bundt C, Allred TB, Bokkour A, Bogatyreva N, Chopik WJ, Antazo B, Behzadnia B, Becker M, Cocco B, Chou WL, Hubena B, Žuro B, Aczel B, Baklanova E, Bai H, Balci BB, Babinčák P, Dixson BJW, Mokady A, Kappes HB, Atari M, Szala A, Szabelska A, Aruta JJB, Domurat A, Arinze NC, Modena A, Adiguzel A, Monajem A, Arabi KAE, Özdoğru AA, Olaya Torres AJ, Theodoropoulou A, Jurković AP, Kassianos AP, Findor A, Hartanto A, Thibault Landry A, Ferreira A, Santos AC, De la Rosa-Gomez A, Gourdon-Kanhukamwe A, Todsen AL, Karababa A, Janak A, Bran A, Tullett AM, Kuzminska AO, Krafnick AJ, Urooj A, Khaoudi A, Ahmed A, Groyecka-Bernard A, Askelund AD, Adetula A, Belaus A, Charyate AC, Wichman AL, Stoyanova A, Greenburgh A, Thomas AG, Arvanitis A, Forscher PS, Mallik PR, Primbs MA, Miller JK, Moshontz H, Urry HL, IJzerman H, Basnight-Brown DM, Chartier CR, Buchanan EM, and Coles NA

Abstract

The COVID-19 pandemic (and its aftermath) highlights a critical need to communicate health information effectively to the global public. Given that subtle differences in information framing can have meaningful effects on behavior, behavioral science research highlights a pressing question: Is it more effective to frame COVID-19 health messages in terms of potential losses (e.g., "If you do not practice these steps, you can endanger yourself and others") or potential gains (e.g., "If you practice these steps, you can protect yourself and others")? Collecting data in 48 languages from 15,929 participants in 84 countries, we experimentally tested the effects of message framing on COVID-19-related judgments, intentions, and feelings. Loss- (vs. gain-) framed messages increased self-reported anxiety among participants cross-nationally with little-to-no impact on policy attitudes, behavioral intentions, or information seeking relevant to pandemic risks. These results were consistent across 84 countries, three variations of the message framing wording, and 560 data processing and analytic choices. Thus, results provide an empirical answer to a global communication question and highlight the emotional toll of loss-framed messages. Critically, this work demonstrates the importance of considering unintended affective consequences when evaluating nudge-style interventions., Competing Interests: Conflict of InterestThe authors declare no conflict of interest., (© The Society for Affective Science 2022.)

Published
2022
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187. Author Correction: A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic.

Author

Wang K, Goldenberg A, Dorison CA, Miller JK, Uusberg A, Lerner JS, Gross JJ, Agesin BB, Bernardo M, Campos O, Eudave L, Grzech K, Ozery DH, Jackson EA, Garcia EOL, Drexler SM, Jurković AP, Rana K, Wilson JP, Antoniadi M, Desai K, Gialitaki Z, Kushnir E, Nadif K, Bravo ON, Nauman R, Oosterlinck M, Pantazi M, Pilecka N, Szabelska A, van Steenkiste IMM, Filip K, Bozdoc AI, Marcu GM, Agadullina E, Adamkovič M, Roczniewska M, Reyna C, Kassianos AP, Westerlund M, Ahlgren L, Pöntinen S, Adetula GA, Dursun P, Arinze AI, Arinze NC, Ogbonnaya CE, Ndukaihe ILG, Dalgar I, Akkas H, Macapagal PM, Lewis S, Metin-Orta I, Foroni F, Willis M, Santos AC, Mokady A, Reggev N, Kurfali MA, Vasilev MR, Nock NL, Parzuchowski M, Espinoza Barría MF, Vranka M, Kohlová MB, Ropovik I, Harutyunyan M, Wang C, Yao E, Becker M, Manunta E, Kaminski G, Boudesseul J, Marko D, Evans K, Lewis DMG, Findor A, Landry AT, Aruta JJB, Ortiz MS, Vally Z, Pronizius E, Voracek M, Lamm C, Grinberg M, Li R, Valentova JV, Mioni G, Cellini N, Chen SC, Zickfeld J, Moon K, Azab H, Levy N, Karababa A, Beaudry JL, Boucher L, Collins WM, Todsen AL, van Schie K, Vintr J, Bavolar J, Kaliska L, Križanić V, Samojlenko L, Pourafshari R, Geiger SJ, Beitner J, Warmelink L, Ross RM, Stephen ID, Hostler TJ, Azouaghe S, McCarthy R, Szala A, Grano C, Solorzano CS, Anjum G, Jimenez-Leal W, Bradford M, Pérez LC, Cruz Vásquez JE, Galindo-Caballero OJ, Vargas-Nieto JC, Kácha O, Arvanitis A, Xiao Q, Cárcamo R, Zorjan S, Tajchman Z, Vilares I, Pavlacic JM, Kunst JR, Tamnes CK, von Bastian CC, Atari M, Sharifian M, Hricova M, Kačmár P, Schrötter J, Rahal RM, Cohen N, FatahModares S, Zrimsek M, Zakharov I, Koehn MA, Esteban-Serna C, Calin-Jageman RJ, Krafnick AJ, Štrukelj E, Isager PM, Urban J, Silva JR, Martončik M, Očovaj SB, Šakan D, Kuzminska AO, Djordjevic JM, Almeida IAT, Ferreira A, Lazarevic LB, Manley H, Ricaurte DZ, Monteiro RP, Etabari Z, Musser E, Dunleavy D, Chou W, Godbersen H, Ruiz-Fernández S, Reeck C, Batres C, Kirgizova K, Muminov A, Azevedo F, Alvarez DS, Butt MM, Lee JM, Chen Z, Verbruggen F, Ziano I, Tümer M, Charyate ACA, Dubrov D, Tejada Rivera MDCMC, Aberson C, Pálfi B, Maldonado MA, Hubena B, Sacakli A, Ceary CD, Richard KL, Singer G, Perillo JT, Ballantyne T, Cyrus-Lai W, Fedotov M, Du H, Wielgus M, Pit IL, Hruška M, Sousa D, Aczel B, Hajdu N, Szaszi B, Adamus S, Barzykowski K, Micheli L, Schmidt ND, Zsido AN, Paruzel-Czachura M, Muda R, Bialek M, Kowal M, Sorokowska A, Misiak M, Mola D, Ortiz MV, Correa PS, Belaus A, Muchembled F, Ribeiro RR, Arriaga P, Oliveira R, Vaughn LA, Szwed P, Kossowska M, Czarnek G, Kielińska J, Antazo B, Betlehem R, Stieger S, Nilsonne G, Simonovic N, Taber J, Gourdon-Kanhukamwe A, Domurat A, Ihaya K, Yamada Y, Urooj A, Gill T, Čadek M, Bylinina L, Messerschmidt J, Kurfalı M, Adetula A, Baklanova E, Albayrak-Aydemir N, Kappes HB, Gjoneska B, House T, Jones MV, Berkessel JB, Chopik WJ, Çoksan S, Seehuus M, Khaoudi A, Bokkour A, El Arabi KA, Djamai I, Iyer A, Parashar N, Adiguzel A, Kocalar HE, Bundt C, Norton JO, Papadatou-Pastou M, De la Rosa-Gomez A, Ankushev V, Bogatyreva N, Grigoryev D, Ivanov A, Prusova I, Romanova M, Sarieva I, Terskova M, Hristova E, Kadreva VH, Janak A, Schei V, Sverdrup TE, Askelund AD, Pineda LMS, Krupić D, Levitan CA, Johannes N, Ouherrou N, Say N, Sinkolova S, Janjić K, Stojanovska M, Stojanovska D, Khosla M, Thomas AG, Kung FYH, Bijlstra G, Mosannenzadeh F, Balci BB, Reips UD, Baskin E, Ishkhanyan B, Czamanski-Cohen J, Dixson BJW, Moreau D, Sutherland CAM, Chuan-Peng H, Noone C, Flowe H, Anne M, Janssen SMJ, Topor M, Majeed NM, Kunisato Y, Yu K, Daches S, Hartanto A, Vdovic M, Anton-Boicuk L, Forbes PAG, Kamburidis J, Marinova E, Nedelcheva-Datsova M, Rachev NR, Stoyanova A, Schmidt K, Suchow JW, Koptjevskaja-Tamm M, Jernsäther T, Olofsson JK, Bialobrzeska O, Marszalek M, Tatachari S, Afhami R, Law W, Antfolk J, Žuro B, Van Doren N, Soto JA, Searston R, Miranda J, Damnjanović K, Yeung SK, Krupić D, Hoyer K, Jaeger B, Ren D, Pfuhl G, Klevjer K, Corral-Frías NS, Frias-Armenta M, Lucas MY, Torres AO, Toro M, Delgado LGJ, Vega D, Solas SÁ, Vilar R, Massoni S, Frizzo T, Bran A, Vaidis DC, Vieira L, Paris B, Capizzi M, Coelho GLH, Greenburgh A, Whitt CM, Tullett AM, Du X, Volz L, Bosma MJ, Karaarslan C, Sarıoğuz E, Allred TB, Korbmacher M, Colloff MF, Lima TJS, Ribeiro MFF, Verharen JPH, Karekla M, Karashiali C, Sunami N, Jaremka LM, Storage D, Habib S, Studzinska A, Hanel PHP, Holford DL, Sirota M, Wolfe K, Chiu F, Theodoropoulou A, Ahn ER, Lin Y, Westgate EC, Brohmer H, Hofer G, Dujols O, Vezirian K, Feldman G, Travaglino GA, Ahmed A, Li M, Bosch J, Torunsky N, Bai H, Manavalan M, Song X, Walczak RB, Zdybek P, Friedemann M, Rosa AD, Kozma L, Alves SG, Lins S, Pinto IR, Correia RC, Babinčák P, Banik G, Rojas-Berscia LM, Varella MAC, Uttley J, Beshears JE, Thommesen KK, Behzadnia B, Geniole SN, Silan MA, Maturan PLG, Vilsmeier JK, Tran US, Izquierdo SM, Mensink MC, Sorokowski P, Groyecka-Bernard A, Radtke T, Adoric VC, Carpentier J, Özdoğru AA, Joy-Gaba JA, Hedgebeth MV, Ishii T, Wichman AL, Röer JP, Ostermann T, Davis WE, Suter L, Papachristopoulos K, Zabel C, Onie S, Ebersole CR, Chartier CR, Mallik PR, Urry HL, Buchanan EM, Coles NA, Primbs MA, Basnight-Brown DM, IJzerman H, Forscher PS, and Moshontz H

Published
2022
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188. Possible kidney-lung cross-talk in COVID-19: in silico modeling of SARS-CoV-2 infection.

Author

Grigoryev DN and Rabb H

Subjects
Animals, Disease Models, Animal, Male, Mice, Mice, Inbred C57BL, COVID-19 complications, Computer Simulation, Kidney Diseases etiology, Lung Diseases etiology, SARS-CoV-2 genetics
Abstract

Background: Publicly available genomics datasets have grown drastically during the past decades. Although most of these datasets were initially generated to answer a pre-defined scientific question, their repurposing can be useful when new challenges such as COVID-19 arise. While the establishment and use of experimental models of COVID-19 are in progress, the potential hypotheses for mechanisms of onset and progression of COVID-19 can be generated by using in silico analysis of known molecular changes during COVID-19 and targets for SARS-CoV-2 invasion., Methods: Selecting condition: COVID-19 infection leads to pneumonia and mechanical ventilation (PMV) and associated with acute kidney injury (AKI). There is increasing data demonstrating mechanistic links between AKI and lung injury caused by mechanical ventilation. Selecting targets: SARS-CoV-2 uses angiotensin-converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2) for cell entry. We hypothesized that expression of ACE2 and TMPRSS2 would be affected in models of AKI and PMV. We therefore evaluated expression of ACE2 and TMPRSS2 as well as other novel molecular players of AKI and AKI-lung cross-talk in the publicly available microarray datasets GSE6730 and GSE60088, which represent gene expression of lungs and kidneys in mouse models of AKI and PMV, respectively., Results: Expression of COVID-19 related genes ACE2 and TMPRSS2 was downregulated in lungs after 6 h of distant AKI effects. The expression of ACE2 decreased further after 36 h, while expression of TMPRSS2 recovered. In kidneys, both genes were downregulated by AKI, but not by distant lung injury. We also identified 53 kidney genes upregulated by PMV; and 254 lung genes upregulated by AKI, 9 genes of which were common to both organs. 3 of 9 genes were previously linked to kidney-lung cross-talk: Lcn2 (Fold Change (FC) Lung (L)  = 18.6, FC Kidney (K)  = 6.32), Socs3 (FC L  = 10.5, FC K  = 10.4), Inhbb (FC L  = 6.20, FC K  = 6.17). This finding validates the current approach and reveals 6 new candidates, including Maff (FC L  = 7.21, FC K  = 5.98)., Conclusions: Using our in silico approach, we identified changes in COVID-19 related genes ACE2 and TMPRSS2 in traditional mouse models of AKI and kidney-lung cross-talk. We also found changes in new candidate genes, which could be involved in the combined kidney-lung injury during COVID-19., (© 2022. The Author(s).)

Published
2022
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189. A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic.

Author

Wang K, Goldenberg A, Dorison CA, Miller JK, Uusberg A, Lerner JS, Gross JJ, Agesin BB, Bernardo M, Campos O, Eudave L, Grzech K, Ozery DH, Jackson EA, Garcia EOL, Drexler SM, Jurković AP, Rana K, Wilson JP, Antoniadi M, Desai K, Gialitaki Z, Kushnir E, Nadif K, Bravo ON, Nauman R, Oosterlinck M, Pantazi M, Pilecka N, Szabelska A, van Steenkiste IMM, Filip K, Bozdoc AI, Marcu GM, Agadullina E, Adamkovič M, Roczniewska M, Reyna C, Kassianos AP, Westerlund M, Ahlgren L, Pöntinen S, Adetula GA, Dursun P, Arinze AI, Arinze NC, Ogbonnaya CE, Ndukaihe ILG, Dalgar I, Akkas H, Macapagal PM, Lewis S, Metin-Orta I, Foroni F, Willis M, Santos AC, Mokady A, Reggev N, Kurfali MA, Vasilev MR, Nock NL, Parzuchowski M, Espinoza Barría MF, Vranka M, Kohlová MB, Ropovik I, Harutyunyan M, Wang C, Yao E, Becker M, Manunta E, Kaminski G, Boudesseu J, Marko D, Evans K, Lewis DMG, Findor A, Landry AT, Aruta JJB, Ortiz MS, Vally Z, Pronizius E, Voracek M, Lamm C, Grinberg M, Li R, Valentova JV, Mioni G, Cellini N, Chen SC, Zickfeld J, Moon K, Azab H, Levy N, Karababa A, Beaudry JL, Boucher L, Collins WM, Todsen AL, van Schie K, Vintr J, Bavolar J, Kaliska L, Križanić V, Samojlenko L, Pourafshari R, Geiger SJ, Beitner J, Warmelink L, Ross RM, Stephen ID, Hostler TJ, Azouaghe S, McCarthy R, Szala A, Grano C, Solorzano CS, Anjum G, Jimenez-Leal W, Bradford M, Pérez LC, Cruz Vásquez JE, Galindo-Caballero OJ, Vargas-Nieto JC, Kácha O, Arvanitis A, Xiao Q, Cárcamo R, Zorjan S, Tajchman Z, Vilares I, Pavlacic JM, Kunst JR, Tamnes CK, von Bastian CC, Atari M, Sharifian M, Hricova M, Kačmár P, Schrötter J, Rahal RM, Cohen N, FatahModares S, Zrimsek M, Zakharov I, Koehn MA, Esteban-Serna C, Calin-Jageman RJ, Krafnick AJ, Štrukelj E, Isager PM, Urban J, Silva JR, Martončik M, Očovaj SB, Šakan D, Kuzminska AO, Djordjevic JM, Almeida IAT, Ferreira A, Lazarevic LB, Manley H, Ricaurte DZ, Monteiro RP, Etabari Z, Musser E, Dunleavy D, Chou W, Godbersen H, Ruiz-Fernández S, Reeck C, Batres C, Kirgizova K, Muminov A, Azevedo F, Alvarez DS, Butt MM, Lee JM, Chen Z, Verbruggen F, Ziano I, Tümer M, Charyate ACA, Dubrov D, Tejada Rivera MDCMC, Aberson C, Pálfi B, Maldonado MA, Hubena B, Sacakli A, Ceary CD, Richard KL, Singer G, Perillo JT, Ballantyne T, Cyrus-Lai W, Fedotov M, Du H, Wielgus M, Pit IL, Hruška M, Sousa D, Aczel B, Hajdu N, Szaszi B, Adamus S, Barzykowski K, Micheli L, Schmidt ND, Zsido AN, Paruzel-Czachura M, Muda R, Bialek M, Kowal M, Sorokowska A, Misiak M, Mola D, Ortiz MV, Correa PS, Belaus A, Muchembled F, Ribeiro RR, Arriaga P, Oliveira R, Vaughn LA, Szwed P, Kossowska M, Czarnek G, Kielińska J, Antazo B, Betlehem R, Stieger S, Nilsonne G, Simonovic N, Taber J, Gourdon-Kanhukamwe A, Domurat A, Ihaya K, Yamada Y, Urooj A, Gill T, Čadek M, Bylinina L, Messerschmidt J, Kurfalı M, Adetula A, Baklanova E, Albayrak-Aydemir N, Kappes HB, Gjoneska B, House T, Jones MV, Berkessel JB, Chopik WJ, Çoksan S, Seehuus M, Khaoudi A, Bokkour A, El Arabi KA, Djamai I, Iyer A, Parashar N, Adiguzel A, Kocalar HE, Bundt C, Norton JO, Papadatou-Pastou M, De la Rosa-Gomez A, Ankushev V, Bogatyreva N, Grigoryev D, Ivanov A, Prusova I, Romanova M, Sarieva I, Terskova M, Hristova E, Kadreva VH, Janak A, Schei V, Sverdrup TE, Askelund AD, Pineda LMS, Krupić D, Levitan CA, Johannes N, Ouherrou N, Say N, Sinkolova S, Janjić K, Stojanovska M, Stojanovska D, Khosla M, Thomas AG, Kung FYH, Bijlstra G, Mosannenzadeh F, Balci BB, Reips UD, Baskin E, Ishkhanyan B, Czamanski-Cohen J, Dixson BJW, Moreau D, Sutherland CAM, Chuan-Peng H, Noone C, Flowe H, Anne M, Janssen SMJ, Topor M, Majeed NM, Kunisato Y, Yu K, Daches S, Hartanto A, Vdovic M, Anton-Boicuk L, Forbes PAG, Kamburidis J, Marinova E, Nedelcheva-Datsova M, Rachev NR, Stoyanova A, Schmidt K, Suchow JW, Koptjevskaja-Tamm M, Jernsäther T, Olofsson JK, Bialobrzeska O, Marszalek M, Tatachari S, Afhami R, Law W, Antfolk J, Žuro B, Van Doren N, Soto JA, Searston R, Miranda J, Damnjanović K, Yeung SK, Krupić D, Hoyer K, Jaeger B, Ren D, Pfuhl G, Klevjer K, Corral-Frías NS, Frias-Armenta M, Lucas MY, Torres AO, Toro M, Delgado LGJ, Vega D, Solas SÁ, Vilar R, Massoni S, Frizzo T, Bran A, Vaidis DC, Vieira L, Paris B, Capizzi M, Coelho GLH, Greenburgh A, Whitt CM, Tullett AM, Du X, Volz L, Bosma MJ, Karaarslan C, Sarıoğuz E, Allred TB, Korbmacher M, Colloff MF, Lima TJS, Ribeiro MFF, Verharen JPH, Karekla M, Karashiali C, Sunami N, Jaremka LM, Storage D, Habib S, Studzinska A, Hanel PHP, Holford DL, Sirota M, Wolfe K, Chiu F, Theodoropoulou A, Ahn ER, Lin Y, Westgate EC, Brohmer H, Hofer G, Dujols O, Vezirian K, Feldman G, Travaglino GA, Ahmed A, Li M, Bosch J, Torunsky N, Bai H, Manavalan M, Song X, Walczak RB, Zdybek P, Friedemann M, Rosa AD, Kozma L, Alves SG, Lins S, Pinto IR, Correia RC, Babinčák P, Banik G, Rojas-Berscia LM, Varella MAC, Uttley J, Beshears JE, Thommesen KK, Behzadnia B, Geniole SN, Silan MA, Maturan PLG, Vilsmeier JK, Tran US, Izquierdo SM, Mensink MC, Sorokowski P, Groyecka-Bernard A, Radtke T, Adoric VC, Carpentier J, Özdoğru AA, Joy-Gaba JA, Hedgebeth MV, Ishii T, Wichman AL, Röer JP, Ostermann T, Davis WE, Suter L, Papachristopoulos K, Zabel C, Onie S, Ebersole CR, Chartier CR, Mallik PR, Urry HL, Buchanan EM, Coles NA, Primbs MA, Basnight-Brown DM, IJzerman H, Forscher PS, and Moshontz H

Subjects
Adult, Female, Humans, Male, COVID-19 psychology, Emotional Regulation, Emotions
Abstract

The COVID-19 pandemic has increased negative emotions and decreased positive emotions globally. Left unchecked, these emotional changes might have a wide array of adverse impacts. To reduce negative emotions and increase positive emotions, we tested the effectiveness of reappraisal, an emotion-regulation strategy that modifies how one thinks about a situation. Participants from 87 countries and regions (n = 21,644) were randomly assigned to one of two brief reappraisal interventions (reconstrual or repurposing) or one of two control conditions (active or passive). Results revealed that both reappraisal interventions (vesus both control conditions) consistently reduced negative emotions and increased positive emotions across different measures. Reconstrual and repurposing interventions had similar effects. Importantly, planned exploratory analyses indicated that reappraisal interventions did not reduce intentions to practice preventive health behaviours. The findings demonstrate the viability of creating scalable, low-cost interventions for use around the world. PROTOCOL REGISTRATION: The stage 1 protocol for this Registered Report was accepted in principle on 12 May 2020. The protocol, as accepted by the journal, can be found at https://doi.org/10.6084/m9.figshare.c.4878591.v1., (© 2021. The Author(s), under exclusive licence to Springer Nature Limited.)

Published
2021
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190. Novel Protective Role of Nicotinamide Phosphoribosyltransferase in Acetaminophen-Induced Acute Liver Injury in Mice.

Author

Zhang LQ, Nsumu M, Huang P, Heruth DP, Riordan SM, Shortt K, Zhang N, Grigoryev DN, Li DY, Friesen CA, Van Haandel L, Leeder JS, Olson J, and Ye SQ

Subjects
Animals, Chemical and Drug Induced Liver Injury etiology, Chemical and Drug Induced Liver Injury metabolism, Chemical and Drug Induced Liver Injury pathology, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Oxidative Stress, Acetaminophen toxicity, Analgesics, Non-Narcotic toxicity, Chemical and Drug Induced Liver Injury prevention & control, Cytokines physiology, Nicotinamide Phosphoribosyltransferase physiology, Protective Agents
Abstract

Acetaminophen overdose is the most common cause of acute liver injury (ALI) or acute liver failure in the United States. Its pathogenetic mechanisms are incompletely understood. Additional studies are warranted to identify new genetic risk factors for more mechanistic insights and new therapeutic target discoveries. The objective of this study was to explore the role and mechanisms of nicotinamide phosphoribosyltransferase (NAMPT) in acetaminophen-induced ALI. C57BL/6 Nampt gene wild-type (Nampt +/+ ), heterozygous knockout (Nampt +/- ), and overexpression (Nampt OE ) mice were treated with overdose of acetaminophen, followed by histologic, biochemical, and transcriptomic evaluation of liver injury. The mechanism of Nampt in acetaminophen-induced hepatocytic toxicity was also explored in cultured primary hepatocytes. Three lines of evidence have convergently demonstrated that acetaminophen overdose triggers the most severe oxidative stress and necrosis, and the highest expression of key necrosis driving genes in Nampt +/- mice, whereas the effects in Nampt OE mice were least severe relative to Nampt +/+ mice. Treatment of P7C3-A20, a small chemical molecule up-regulator of Nampt, ameliorated acetaminophen-induced mouse ALI over the reagent control. These findings support the fact that NAMPT protects against acetaminophen-induced ALI., (Copyright © 2018 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.)

Published
2018
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191. Transcriptional analysis of infiltrating T cells in kidney ischemia-reperfusion injury reveals a pathophysiological role for CCR5.

Author

Ko GJ, Linfert D, Jang HR, Higbee E, Watkins T, Cheadle C, Liu M, Racusen L, Grigoryev DN, and Rabb H

Subjects
Animals, Antibodies, CD3 Complex genetics, CD3 Complex metabolism, Chemokines genetics, Chemokines metabolism, Cluster Analysis, Enzyme-Linked Immunosorbent Assay, Gene Expression Profiling, Kidney cytology, Kidney Diseases metabolism, Kidney Diseases physiopathology, Male, Mice, Receptors, CCR5 genetics, Reperfusion Injury metabolism, Specific Pathogen-Free Organisms, Gene Expression Regulation physiology, Kidney injuries, Kidney pathology, Receptors, CCR5 metabolism, Reperfusion Injury physiopathology, T-Lymphocytes metabolism
Abstract

Although T cells have been shown to play a direct role in kidney ischemia-reperfusion injury (IRI), little is known about the underlying mechanisms. We hypothesized that studying the transcriptional responses in kidney-infiltrating T cells would help elucidate novel therapeutic targets for kidney IRI. Unilateral renal pedicle clamping for 45 min was performed in male C57BL/6 mice, and CD3(+) T cells were isolated from the kidney and purified. Transcriptional activities of T cell were measured by array-based PCR compared between ischemic kidneys and contralateral nonischemic kidneys. Among total of 89 genes analyzed, 24, 22, 24, and 37 genes were significantly changed at 6 h, day 3, day 10, and day 28 after IRI. Genes associated with cytokines, chemokines, and costimulatory molecules were upregulated. Pathway analysis identified CC motif chemokine receptor 5 (CCR5) as a candidate pathophysiological pathway. CCR5 upregulation was validated at the protein level, and CCR5 blockade improved renal function after kidney IRI. Using discovery techniques to identify transcriptional responses in purified kidney-infiltrating cells enabled the elucidation of novel mechanisms and therapeutic targets for IRI.

Published
2012
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