1,167 results on '"G. Muhr"'
Search Results
152. Poster
- Author
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A. Kaminski, U. Rohr, EJ. Müller, and G. Muhr
- Published
- 2002
153. [Complications in the use of the halo fixator]
- Author
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W, Schulze, S A, Esenwein, E J, Müller, O, Russe, and G, Muhr
- Subjects
Adult ,Aged, 80 and over ,Male ,Analgesics ,Pain, Postoperative ,Time Factors ,Adolescent ,External Fixators ,Middle Aged ,Interviews as Topic ,Quality of Life ,Humans ,Female ,Aged ,Follow-Up Studies ,Retrospective Studies - Abstract
50 patients out of a total of 88 who underwent treatment using a halo-fixateur between 1987 and 1997 were available for a follow-up interview reviewing local complications and quality of life. Marginal discomfort was observed in 54% of patients, moderate complaints/transitory pain in 30%, prolonged and severe discomfort and pain in 16%. 62% of patients took no analgetics, 22% infrequently, and 16% continuously throughout treatment. In pin-tract infection local treatment was successful in 6 patients, in 3 patients the screws needed to be relocated. Complaints of dysphagia due to extended forced lordosis of the cervical spine could be corrected by adjusting the position of the halo ring in 3 out of 8 patients. 3 patients developed pressure sores which could be managed without surgical intervention. Proper fixation and placement of the pin-tracts are crucial in the application of the halo fixateur if complications are to be avoided. Superficial infections must be treated locally. If the infection persists immediate pin relocation and systemic antibiotic therapy have to be initiated.
- Published
- 2001
154. TGFbeta1 and TGFbeta2 mRNA and protein expression in human bone samples
- Author
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Andreas Pfeiffer, G. Muhr, C. Jost, J. Janott, Helmut Schatz, Steffen Hering, F. Isken, C. Knabbe, and A. Pommer
- Subjects
Gene isoform ,Adult ,Male ,medicine.medical_specialty ,Aging ,Adolescent ,Endocrinology, Diabetes and Metabolism ,Gene Expression ,Biology ,Bone and Bones ,Bone remodeling ,Extracellular matrix ,Transforming Growth Factor beta1 ,Fractures, Bone ,Transforming Growth Factor beta2 ,Endocrinology ,Transforming Growth Factor beta ,Internal medicine ,Gene expression ,Osteoarthritis ,Internal Medicine ,medicine ,Humans ,RNA, Messenger ,Chromatography, High Pressure Liquid ,Aged ,Aged, 80 and over ,Messenger RNA ,Reverse Transcriptase Polymerase Chain Reaction ,RNA ,Osteoblast ,General Medicine ,Transforming growth factor beta ,Middle Aged ,medicine.anatomical_structure ,embryonic structures ,biology.protein ,Female - Abstract
Transforming growth factor beta is one of the most abundant growth factors stored in bone. It is known as a potent regulator of osteoblast proliferation and differentiation as well as of production extracellular matrix. We established a highly specific RT-PCR in combination with HPLC for detection and quantification of TGFbeta1 and TGFbeta2 mRNA expression in 89 human bone samples. Levels of TGFbeta1 protein ranged between 27 and 580 ng/g bone (mean 188 +/- 15 ng/g; n=75) and for TGFbeta2 between 7.2 and 35 ng/g bone (mean 14.3 +/- 2.1 ng/g; n=57). TGFbeta1 and TGFbeta2 protein concentrations and TGFbeta isoform mRNA expression in bone were not significantly different between the sexes. TGFbeta isoform mRNA expression as well as protein content in bone declined age dependently. TGFbeta1 and TGFbeta2 protein and mRNA expression were different in bone samples from different sites of the skeleton indicating in part the regulation by mechanical stimuli. In contrast to TGFbeta1, TGFbeta2 mRNA expression was significantly enhanced in osteoarthritic bone compared to unaffected bone. These data are in concordance to previous results concerning the expression of TGFbeta3 in bone. In conclusion, the data suggest distinct patterns' of expression of the TGFbeta isoforms under physiological and pathological conditions in bone.
- Published
- 2001
155. [Supracondylar femoral fractures in knee endoprostheses. Stabilizing with retrograde interlocking nail]
- Author
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M, Wick, E J, Müller, and G, Muhr
- Subjects
Aged, 80 and over ,Male ,Reoperation ,Knee Injuries ,Middle Aged ,Fracture Fixation, Intramedullary ,Radiography ,Postoperative Complications ,Humans ,Female ,Knee Prosthesis ,Femoral Fractures ,Aged ,Follow-Up Studies ,Retrospective Studies - Abstract
The treatment of supracondylar fractures of the femur in total knee arthroplasty is still challenging, and a variety of methods has been recommended. In a retrospective analysis, we reviewed six patients (average age: 70.5 years) with this type of fracture that had been stabilized with a retrograde intramedullary locking nail [Green-Seligson-Henry (GSH) nail]. The fracture had occurred 34.5 months after implantation of total knee arthroplasty. The average time of the operation was 97.16 min. There were no intra- or postoperative complications. All patients could be followed up at 17.3 months on average. Fracture healing was uneventful in all six cases. The postoperative range of motion was similar to the prefracture level in five patients. One patient demonstrated a loss of extension (10 degrees) associated with a valgus malalignment of 10 degrees. According to our experience, retrograde intramedullary nailing of supracondylar fractures in total knee arthroplasty is a promising alternative, which allows closed reduction and preservation of the soft tissue envelope. Immediate mobilization with partial weight bearing is possible, and the rate of complications is low.
- Published
- 2001
156. Analysis of TGFbeta3 gene expression and protein levels in human bone and serum
- Author
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C. Jost, G. Muhr, Andreas Pfeiffer, A. Pommer, F. Isken, Helmut Schatz, J. Janott, and Steffen Hering
- Subjects
Adult ,Male ,medicine.medical_specialty ,Aging ,Adolescent ,Endocrinology, Diabetes and Metabolism ,Bone tissue ,Bone and Bones ,Bone remodeling ,Endocrinology ,Transforming Growth Factor beta3 ,Transforming Growth Factor beta ,Internal medicine ,Blood plasma ,Gene expression ,Osteoarthritis ,Internal Medicine ,medicine ,Distribution (pharmacology) ,Humans ,Tissue Distribution ,Insulin-Like Growth Factor I ,Aged ,Aged, 80 and over ,Messenger RNA ,biology ,General Medicine ,Middle Aged ,In vitro ,medicine.anatomical_structure ,Osteocalcin ,biology.protein ,Female - Abstract
Recent data indicate that TGFbeta3, one member of the TGFbeta-isoforms, has an important role in bone remodeling. Up to date little is known about the expression and regulation of TGFbeta3 in man. We established a highly specific ELISA for quantitative measurement of TGFbeta3 in bone and blood samples and a RT-PCR in combination with HPLC for detection and quantification of TGFbeta3 mRNA in 89 human bone samples. Levels of TGFbeta3 protein ranged between 30 and 66 pg/mg bone (mean 36,6 +/-1,03 pg/mg) and between 30 and 1910 pg/ml in serum (mean 128.9+/-38.9 pg/ml). TGFbeta3 mRNA expression as well as protein levels in serum and in bone declined age dependently. No specific load- or site-specific distribution of TGFbeta3 mRNA expression or protein content was detected at different sites indicating an absence of mechanical regulation. Protein levels of TGFbeta3 in serum correlated with TGFbeta3 mRNA expression in bone (p= 0.0027; r=0.49). By contrast, TGFbeta3 protein levels stored in the bone matrix were not related to TGFbeta3 mRNA reflecting the long term process of TGFbeta3 deposition during bone remodeling. Notably TGFbeta3 serum levels were highly correlated with IGF-I and osteocalcin levels in serum. We conclude that TGFbeta3 in man circulates in significant amounts which appears to be representative for TGFbeta3 expression in bone tissue and may be in part derived from bone. The high correlation of TGFbeta3 with IGF-I suggests parallel systemic principles of regulation.
- Published
- 2001
157. Decreased leukotriene release from neutrophils after severe trauma: role of immature cells
- Author
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M, Köller, M, Wick, and G, Muhr
- Subjects
Adult ,Male ,Leukotrienes ,Arachidonate 5-Lipoxygenase ,Adolescent ,Ionophores ,Multiple Trauma ,Neutrophils ,Blotting, Western ,Immunologic Deficiency Syndromes ,Cell Differentiation ,Middle Aged ,Leukotriene B4 ,Enzyme Induction ,Humans ,Female ,Calcium Signaling ,Inflammation Mediators ,Calcimycin ,Cellular Senescence ,Chromatography, High Pressure Liquid - Abstract
Polymorphonuclear granulocytes (PMN) play a key role in host defense against microbial infections. After severe trauma PMN show cellular dysfunctions including chemotactic migration, phagocytosis, and bacterial killing. In these settings the contribution of the cellular maturation stage compared to functional activities has not been investigated. Polymorphonuclear granulocytes are potent producers of lipid mediators via the 5-lipoxygenase (5-LO) pathway (leukotrienes, LTs) which exert important proinflammatory and immunoregulatory activities. We analyzed leukotriene generation from PMN-fractions (N = 23) of 15 polytrauma patients in comparison to 17 healthy donor cell fractions and correlated this lipid mediator release to the hematopoietic maturation stage of respective PMN. Polymorphonuclear granulocytes were isolated from EDTA-anticoagulated peripheral blood employing a one step procedure based on a discontinuous double Ficoll-gradient. Cells (5 x 10(6)/500 microl phosphate-buffered saline) were stimulated for 20 min at 37 degrees C with 1 microM Ca-ionophor A23187 in the presence of 1 mM Ca++ and 0.5 mM Mg++. Leukotrienes were analyzed by reversed-phase HPLC. Expression of 5-lipoxygenase (5-LO) was additionally determined by Western blot. Maturation stage of PMN was quantitated by Pappenheim-staining of cell smears. After polytrauma the generation of leukotrienes from PMN was individually diminished. Synthesis of enzymatically formed metabolites (LTB4, OH-LTB4 and COOH-LTB4) was concomitantly reduced. The decresaed leukotriene synthesis strongly correlated (r2 = 0.907, P0.0001) to the occurrence of immature PMN (mostly band cells). The expression of 5-lipoxygenase in PMN fractions consisting mainly of band cells was decreased. Our results provide evidence that posttraumatic granulocyte dysfunction is partly due to immature functional cell capacities.
- Published
- 2001
158. [The diagnostic concept of acute infection of the shoulder joint]
- Author
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T, Ambacher, S, Esenwein, E, Kollig, and G, Muhr
- Subjects
Adult ,Diagnostic Imaging ,Male ,Arthritis, Infectious ,Bacteriological Techniques ,Shoulder Joint ,Bacterial Infections ,Middle Aged ,Arthroscopy ,C-Reactive Protein ,Predictive Value of Tests ,Acute Disease ,Humans ,Female ,Range of Motion, Articular ,Algorithms ,Aged ,Retrospective Studies ,Ultrasonography - Abstract
It is generally accepted that septic conditions of the shoulder often lead to an earnest situation with joint damage. Because of the low incidence of shoulder infections there are only a few cases reported in the literature. Therefore, unlike joint infections of the knee no diagnostic and therapeutic standard procedure is documented for the shoulder.In a retrospective study the results of 15 patients with a surgical revision at the BG-Clinic-Bergmannsheil-Bochum between 1 January 1989 and 31 August 1999 after an infection of the shoulder joint were analyzed. We registered the following parameters: etiology, intervall until the first clinical symptoms, clinical signs, diagnostic procedure, intraoperative site (Gächter classification), and operative treatment. The diagnostic procedure followed an algorithm, including CRP-determination, ultrasound of the shoulder, ultrasound-guided aspiration and a Gram stain. If the result was positive, surgical joint revision followed. The infection stage was classified intraoperatively according to the criteria of the Gächter classification. Eight patients were reexamined after an average follow-up of 4.8 years.Fourteen infections followed injection. All patients demonstrated increasing CRP levels and a painful limited range of motion. In all Gram stains we detected bacterial organisms. The diagnosis of an acute infection according to the criteria of this diagnostic algorithm was verified intraoperatively in all 15 joints. Two patients with delayed admission died postoperatively due to septic multiorgan failure despite maximal treatment under intensive care conditions.If there are suspicious clinical symptoms after a typical anamnesis, we recommend an immediate diagnostic algorithm, including CRP determination, ultrasound of the shoulder, ultrasound-guided joint puncture and a Gram stain. If there is acute joint infection, time-consuming diagnostic procedures must be avoided because of the risk of secondary reduced joint mobility or life-threatening complications.
- Published
- 2001
159. Schultergelenkfrakturen im Alter
- Author
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I. Reich, O. Gimm, V. Lippert, W. Rothfischer, T. Gross, P. M. Sutter, P. Regazzoni, E. Brück, A. Junge, T. v. Garrell, G. Böhringer, L. Gotzen, K. Hahn, J. Schmidt, H. Grosse-Leege, K. H. Winker, T. Glombik, E. Kollig, O. Russe, A. Schönwasser, G. Muhr, S. Pokar, O. Holbein, L. Kinzl, G. Hehl, Chr. Ulrich, B. Gmelich, G. Kelsch, H. Seitz, C. Liegi, D. Brass, H. Reichel, M. Müller, A. Schmid, F. Gohlke, T. D. Böhm, and A. Werner
- Published
- 2001
160. Experimentelle Unfallchirurgie
- Author
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F. Adam, D. Pape, K. Schiel, D. Kohn, S. Rupp, J. Richter, B. Clasbrummel, G. Muhr, R. Hente, J. Lechner, B. Füchtmeier, U. Schlegel, S. M. Perren, A. M. Halder, M. Zobitz, K.-N. An, S. Weindel, R. Schmidt, H. Gerngroß, L. Claes, M. Lucke, G. Schmidmaier, R. Schiller, S. Sadoni, B. Wildemann, M. Raschke, A. Kreutz, P. Kirschner, A. Schmeling, K. Ito, R. Wieling, M. Kääb, M. Schütz, M. Sauerbier, M. Fujita, M. E. Hahn, P. G. Neale, R. A. Berger, T. Schmickal, and A. Wentzensen
- Published
- 2001
161. Verbesserung der biokompatibilität von ni-ti-formgedächtnislegierungen ('nitinol') durch beschichtung mit calciumphosphaten aus lösung
- Author
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Matthias Epple, Manfred R. Koller, G. Muhr, D. Müller, and J. S. Choi
- Subjects
Chemistry ,Biomedical Engineering ,Chemie - Published
- 2001
162. Kniegelenkendoprothetik
- Author
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R. Neugebauer, W. Puhl, W. Neumann, V. Ewerbeck, H. J. Refior, W. Plitz, J. Schunck, T. Filler, E. Peuker, J. Jerosch, U. Clemens, R. K. Miehlke, J. Jens, M. Börner, M. Tenbusch, U. Wiesel, R. Ascherl, E. Lenz, H. Albersdörfer, A. Kölling, E. W. Kollig, F. Kutscha-Lissberg, B. Kroes, and G. Muhr
- Published
- 2001
163. Innovationen
- Author
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M. Raschke, C. Csimma, A. Valentin-Opran, W. Fabry, Ch. Bettag, H. Hirche, H.-J. Kock, W. Ditzen, Martin Börner, J. Hensel, T. Radebold, H. Burchhardt, K. M. Stürmer, S. A. Esenwein, F. Hopf, A. Pommer, F. Kutscha-Lissberg, E. Kollig, G. Muhr, U. Berlemann, T. Franz, P. F. Heini, M. Grotz, H. Baur, H.-C. Pape, C. Krettek, T. R. Neubert, M. Baacke, R. Stiletto, E. Freyenhagen, L. Gotzen, P. Voeltz, W. Hasse, M. Faschingbauer, E. A. H. Euler, S. Wirth, U. Linsenmaier, W. Mutschler, F. Kleinod, M. Putzier, H. Zippel, H. Veigel, B. Clasbrummel, N. Reckwitz, A. Bolz, M. Schieri, and J. Petermann
- Published
- 2001
164. Schultergelenkfrakturen im Alter
- Author
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V. Echtermeyer, S. Bartsch, L. Kinzl, O. J. Russe, E. Kollig, B. Roetmann, E. Weitknecht, A. Pommer, A. Dávid, A. Anselmann, P. Kirschner, M. Fuchs, A. Losch, H. Burchhardt, K. M. Stürmer, T. Rose, H. Lill, P. Hepp, J. Korner, Ch. Josten, J. Friese, E. Mielke, G. Muhr, P. M. Hahn, M. Runkel, A. Noltze, and P. M. Rommens
- Published
- 2001
165. Experimentelle Unfallchirurgie
- Author
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M. van Griensven, K. Hucke, H.-C. Pape, C. Krettek, St. Arens, U. Schlegel, D. Pfluger, H. Eijer, J. Textor, C. Kraft, R. A. Laun, O. Schröder, D.-L. Herrmann, K.-M. Schulte, H.-D. Röher, A. Ekkernkamp, M. R. Raum, R. Linker, S. Gregor, D. Rixen, T. Tiling, R. Zander, E. Neugebauer, A. G. Schock, null Trauma, S. Katscher, T. Frenkel, C. Josten, M. Majetschak, M. Heesen, G. Voggenreiter, M. Bardenheuer, U. Obertacke, F. U. Schade, L. Mende, T. Lorenz, L. Engelmann, M. Köller, F. Kutscha-Lissberg, G. Muhr, S. Lendemans, E. Kreuzfelder, C. Waydhas, S. Flohe, D. Schreiter, S. Müller, K. Eid, M. Keel, O. Trentz, W. Ertel, U. C. Liener, M. W. Knöferl, T. Barth, U. B. Brückner, L. Kinzl, F. Gebhard, B. J. Kinner, L. C. Gerstenfeld, T. A. Einhorn, K. P. Thon, and M. Spector
- Published
- 2001
166. Proximale Femurfrakturen
- Author
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G. Kelsch, F. Balz, Chr. Ulrich, T. Gausepohl, K. Mader, S. Harnoss, J. Koebke, D. Pennig, M. Felenda, M. Rapp, K.-K. Dittel, T. Fischer, R. Sperling, B. Sauerwein, T. von Garrel, R. Stiletto, M. Wurm, M. E. Wenzl, M. Faschingbauer, Ch. Jürgens, P. Klever, H. M. Rau, H. J. Erli, U. Witzel, O. Paar, J.-C. Renggli, R. Babst, P. Regazzoni, P. Messmer, F. Hopf, E. Kollig, T. M. Frangen, and G. Muhr
- Published
- 2001
167. Proximale Tibiafrakturen und Begleitverletzungen
- Author
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P. M. Rommens, F. Kutscha-Lissberg, G. Muhr, Reinhard Schnettler, M. Jackel, Markus D. Schofer, A. Dávid, E. Kollig, C. Simanski, Ch. Schmidt, A. B. Imhoff, M. Runkel, C. Josten, A. Scherenberg, H. Seikmann, T. Tiling, Horst-Rainer Kortmann, Ch. Jürgens, S. A. Esenwein, A. Tiemann, M. E. Wenzl, L. Gotzen, D. Schmischke, A. Pommer, B. Bouillon, W. Kolb, M. Jessel, S. Fuchs, A. C. Burkart, E. Markgraf, L. Harder, M. Hansen, Ch. Rülander, D. v.d. Heyde, and R. Babst
- Published
- 2001
168. [Spinal contusion after trauma to the cervical spine--relevance of the sagittal diameter of the spinal canal]
- Author
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M, Wick, E J, Müller, M P, Hahn, and G, Muhr
- Subjects
Adult ,Male ,Neurologic Examination ,Adolescent ,Anthropometry ,Contusions ,Middle Aged ,Quadriplegia ,Radiography ,Spinal Stenosis ,Risk Factors ,Cervical Vertebrae ,Humans ,Female ,Spinal Cord Injuries ,Aged - Abstract
The purpose of this study was to analyze the relationship between spinal stenosis and cervical myelopathy. Furthermore it was to investigate whether there is a correlation between spinal stenosis and progression of neurologic symptoms?Using the Pavlov ratio method, we compared 14 patients with a contusio spinalis with 14 patients who suffered from a distortion of the cervical spine. This ratio is calculated by the sagittal diameter of the spinal canal with the anteroposterior width of the vertebral body.In eight patients with a contusio spinalis, there was a spinal stenosis, while there was none in the distortion group. The remaining patients with a contusio had severe degenerative changes in routine roentgenograms of the cervical spine. The Pavlov ratio was statistically significant reduced in the contusio group. After 8.5 days there was a complete regression of neurologic symptoms, whereas in 4 patients there was no full recovery.To conclude we demonstrated that a spinal stenosis promotes a contusio spinalis but there is no evidence that the Pavlov ratio allows statements concerning the progression of the injury.
- Published
- 2000
169. [Diaphyseal femur pseudarthroses--only a technical problem?]
- Author
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J, Richter, W, Schulze, and G, Muhr
- Subjects
Adult ,Aged, 80 and over ,Fracture Healing ,Male ,Reoperation ,Adolescent ,Middle Aged ,Fracture Fixation, Intramedullary ,Radiography ,Fracture Fixation, Internal ,Pseudarthrosis ,Postoperative Complications ,Child, Preschool ,Humans ,Surgical Wound Infection ,Female ,Treatment Failure ,Child ,Femoral Fractures ,Aged - Abstract
Between 1981 and 1994 at the Bergmannsheil Ruhr University Hospital in Bochum, Germany, we treated 145 patients with femoral diaphyseal nonunions following initial operative treatment. Of these patients, 138 received this initial operative treatment at an outside institution. The primary reconstructions for the fractures utilized plates in 112 cases, reamed nails in 24 cases and external fixators in 9 cases. The average age of the patients was 35 years and the mean time from the initial operative treatment was 2 years. Twenty-seven patients (19%) presented with a hypertrophic nonunion and 118 (81%) with an atrophic nonunion. There was a significant correlation between primary "classic" plating and development of an atrophic nonunion (chi 2-test: P0.01). We observed 34 wound infections (23%) with no significant correlation to the type of primary osteosynthesis. We determined that 73 of the pseudarthroses were due to improper osteosynthesis techniques. Of these cases, 41% involved the use of plates, 83% involved the use of reamed nails, and 78% involved the use of external fixators. Fracture location near the diaphyseal-metaphyseal junctions was common in this problematic group. Ninety-two percent of all plates led to atrophic nonunions. There were 21 open fractures and of these 90% (n = 19) developed an atrophic pseudarthrosis and 29% (n = 6) developed a wound infection. Fifty-seven (39%) of all patients had additional injuries, but we found that did not increase the risk of disturbed bone healing. Our revision operations focused on the elimination of wound infections, refreshment of bone healing, and improvement in fragment stability. Only 28% of all "classic" plates and 11% of all external fixators were changed to an intramedullary implant at the time of the first revision surgery. Hypertrophic nonunions required a mean of 1.3 revision operations to achieve bone healing whereas a mean of 2 revision operations were necessary to fuse atrophic bone ends (P0.05). In cases of diaphyseal pseudarthrosis healing time was not affected by the type of osteosynthesis used for primary reconstructions. Since lack of fracture healing can often already be observed directly from postoperative X-rays, we recommend that revision procedures be performed early. The prolonged length of time to care for femoral nonunions underlines the importance of appropriate primary fracture treatment. That takes into consideration both the biomechanical and the biological aspects of bone healing.
- Published
- 2000
170. [Does liberation of interleukin-12 correlate with the clinical course of polytraumatized patients?]
- Author
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M, Wick, E, Kollig, M, Walz, G, Muhr, and M, Köller
- Subjects
Adult ,Male ,Adolescent ,Critical Care ,Multiple Trauma ,Multiple Organ Failure ,Middle Aged ,Prognosis ,Interleukin-12 ,Systemic Inflammatory Response Syndrome ,Survival Rate ,Injury Severity Score ,Reference Values ,Humans ,Female ,Aged - Abstract
Interleukin-12-p70 (IL-12-p70) is a potent immunoregulatory cytokine composed of a heavy chain (p40) and a light chain (p35). Contradicting results have been reported with regard to leukocyte release and systemic concentration of IL-12 after polytrauma.We daily analyzed systemic concentrations of IL-12 in polytrauma patients (n = 37, mean ISS 33.9) in comparison to healthy donor values during intensive care course by ELISA. Patients were divided according to their mean IL-12 levels into those with elevated IL-12 (group 1, n = 7), those with decreased IL-12 (group 2, n = 4) and those with IL-12 in the normal range (group 3, n = 26).Patients in group 1 revealed elevated levels of IL-12 up to p701000 pg/ml and p402500 pg/ml. The common clinical feature of group 1 was a thorax trauma in combination with pneumonia (85% survivors). Patients with single thorax trauma or pneumonia without thorax trauma (group 3) showed normal IL-12 values. Patients with decreased IL-12 levels revealed also a thorax trauma and pneumonia but all patients succumbed. The groups significantly differ in their stay in the intensive care unit, in TISS, in MODS score and in respiratory ratio, but not in ISS, mean CRP values and leukocyte counts. Correlation analysis revealed no significant relation between systemically altered IL-12 values and clinical parameters, with the exception of a negative correlation of p70 and ISS (r = -0.785) or MODS score (r = -0.314) in group 1.After major injuries there is no overall suppression of IL-12 formation. Patients with normal or elevated IL-12 levels belong mainly to the survivors, whereas patients with decreased IL-12 levels are at high risk of succumbing to multi-organ failure.
- Published
- 2000
171. [Chronic venous insufficiency after open tibial fracture. An underestimated problem]
- Author
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J, Buchholz, G, Möllenhoff, M, Reckert, and G, Muhr
- Subjects
Adult ,Male ,Soft Tissue Injuries ,Postphlebitic Syndrome ,Middle Aged ,Thrombophlebitis ,Varicose Ulcer ,Plethysmography ,Tibial Fractures ,Fractures, Open ,Postoperative Complications ,Venous Insufficiency ,Humans ,Female ,Aged ,Follow-Up Studies ,Retrospective Studies - Abstract
There is a wide range of alternatives for primary bone reconstruction in the treatment of open lower leg fractures with soft tissue damage of the type Gustillo II and III. The primary objective should always be the protection of soft tissue damage whether one uses the fixateur externe, or an unreamed nail or primary bone shortening with secondary callus distraction. In recent years, this approach has produced better results and a reduction in the rate of major amputations. The overall effects of the initial treatment can only be analysed after a number of years. Research results indicate long-term soft tissue complications of the lower leg, varying from harmless swelling to venous ulcer. We conducted a clinical investigation which compared 80 patients, who were treated between 1985 and 1994 using the venous-occlusion plethysmography, to 50 healthy individuals. Clinically significant damage of the deep venous system was found in over 50% of cases. There was a direct correlation between the number of years since the initial treatment and the degree of damage found. Based on these findings, we recommend that the initial treatment of this condition and the preventative treatment of the secondary trauma diseases should follow regulated surgical guidelines and be recognised for insurance purposes.
- Published
- 2000
172. [Fatal soft tissue infections after arthroscopy of the knee joint. A diagnostic or therapeutic problem?]
- Author
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S A, Esenwein, E, Kollig, F, Kutscha-Lissberg, T, Klapperich, and G, Muhr
- Subjects
Male ,Arthritis, Infectious ,Arthroscopy ,Knee Joint ,Synovectomy ,Sepsis ,Soft Tissue Infections ,Humans ,Middle Aged ,Staphylococcal Infections ,Shock, Septic ,Algorithms ,Anti-Bacterial Agents - Abstract
After detection of a bacterial infection of the joint, an absolute indication for intervention is given. Systemic antibiotic drug therapy is indicated and drainage of the joint has to be performed immediately. The following therapeutic algorithm regimen is a proven remedy in treating pyoarthrosis of the knee joint: During the initial period, the infection can be controlled by arthroscopic irrigation and systemic antibiotic therapy. Depending on the progredient findings or if the symptoms persist, curing the joint by open synovectomy is the next step of treatment. If open joint revision including synovectomy is not performed or is performed too late, there will be a threat of irreversible damage of the afflicted joint up to septic spread endangering the patient's life. We report on two patients suffering from generalized sepsis resulting in death after delayed therapy for knee joint infection. Regarding the presented cases, it can be concluded that indication to early surgical joint debridement including open synovectomy of the knee is still rarely seen after development of pyoarthritis.
- Published
- 2000
173. [Acute pseudo-obstruction of the colon as complication of hip surgery]
- Author
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M, Wick, D, Martin, E J, Müller, and G, Muhr
- Subjects
Aged, 80 and over ,Male ,Hip ,Hip Fractures ,Colonic Pseudo-Obstruction ,Decompression, Surgical ,Osteoarthritis, Hip ,Femoral Neck Fractures ,Postoperative Complications ,Acute Disease ,Humans ,Female ,Aged ,Retrospective Studies - Abstract
Pseudo-obstruction of the colon is characterized by a massive colonic dilatation without mechanical obstruction. It is rarely after hip surgery, however, untreated it may be complicated by a life threatening perforation of the colon. In a retrospective analysis we reviewed 11 patients (4 women, 7 men, mean age 75.2 years, range 67 to 86 years) with pseudo-obstruction of the colon after hip surgery in the years 1995 to 1998. In relation to all patients aged 65 years and older who underwent surgery of the hip, the prevalence was 1.06%. The leading clinical symptom was abdominal distension. On plain x-rays, dilatation of the colon measured 13.3 cm on average (9-16 cm). In two patients (18%) adequate application of drugs stimulating the gastro-intestinal motility was sufficient, whereas in 8 patients (73%) colonoscopic decompression had to be performed. In three of these, the procedure failed and because of persistent symptoms a cecostomy was performed. One patient underwent immediate laparotomy because of peritonitis. 2 patients (18%) died because of a complicated course. Non operative treatment should not exceed 24 hours, endoscopic decompression and tube placement is considered as the treatment of choice. In cases of failure of these procedures, perforation of the colon and/or peritonism, urgent laparotomy with open decompression by a cecostomy is essential.
- Published
- 2000
174. [Pattern of injuries and prophylaxis in paragliding]
- Author
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W, Schulze, B, Hesse, G, Blatter, B, Schmidtler, and G, Muhr
- Subjects
Adult ,Male ,Adolescent ,Protective Devices ,Middle Aged ,Sports Equipment ,Fractures, Bone ,Accident Prevention ,Protective Clothing ,Germany ,Athletic Injuries ,Humans ,Female ,Switzerland ,Retrospective Studies ,Sports - Abstract
This study will present trends and recommendations to increase active and passive safety in paragliding on the basis of current state-of-the-art equipment and typical patterns of injury. This German-Swiss teamwork presents data of 55 male and 9 female patients treated after paragliding accidents between 1994 to 1998 respectively 1996 to 1998. 43.7% of the pilots presented with multiple injuries, 62.5% suffered spinal fractures and 18.8% pelvic fractures. 28.4% of the injured pilots were admitted with injuries of the lower extremities mainly affecting the tarsus or the ankle joint. Only three patients with single injuries could be treated in an ambulatory setting. 54.0% of the injuries left the patients with lasting functional residues and complaints. Main causes of accidents were either pilot error in handling the paraglider or general lack of awareness about potential risk factors. 46.0% of injuries occurred during landing, 42.9% of injuries during the flight and another 11.1% of injuries during starting procedures. With noticeable enhanced performance sails of the beginners and intermediate level are increasingly popular. Protective helmets and sturdy footwear reaching above the ankle joint are indispensable pieces of equipment. The use of protective gloves is highly recommended. Back protection devices of the new generation provide the best passive prophylaxis for the pilot against pelvic and spinal cord injuries. This area hold the most promise for increasing safety and reducing risk of injury in future, apart from using beginners and intermediate wings. After acquisition of the pilot license performance and security training provide the best preparing to master unforeseeable situations.
- Published
- 2000
175. [Fracture management in the aged]
- Author
-
F, Kutscha-Lissberg, E, Kollig, M, Keller, and G, Muhr
- Subjects
Aged, 80 and over ,Male ,Reoperation ,Fracture Fixation, Internal ,Fractures, Bone ,Postoperative Complications ,Humans ,Female ,Aged - Abstract
Fracture care in a geriatric population should lead to a mobilisation with full weight bearing as soon as possible after the accident. Osteoporosis and associated preexisting disease influences the kind of fracture care as well as the social situation. A retrospective analysis of 888 consecutive patients from 1994 to 1998 showed that the fracture risk for a second independent bony lesion was 5.2% in this population with a mean age of 83.4 years (75 y-97.2 y). 946 fractures were treated operatively with a overall reoperation rate of 10%. 3.1% were soft tissue revisions due to infection, 2.0% were because of implant failure in connection with a deep infection and 5.2% of the reoperation were indicated because of implant failure alone. Distribution of complications showed the advantage of closed, indirect reduction and intramedullary devices and primary hemiarthroplasty in femoral and humeral head fractures.
- Published
- 2000
176. [Femoral neck fracture. Osteosynthesis or which endoprosthesis is indicated?]
- Author
-
G, Möllenhoff, M, Walz, B, Clasbrummel, and G, Muhr
- Subjects
Male ,Radiography ,Reoperation ,Fracture Fixation, Internal ,Postoperative Complications ,Arthroplasty, Replacement, Hip ,Bone Screws ,Humans ,Female ,Prosthesis Design ,Aged ,Femoral Neck Fractures ,Follow-Up Studies - Abstract
Femoral neck fractures are frequent fractures of the elderly. They can be treated by the use of dynamic hip screws, lag screws, bipolar hemi-protheses or total hip replacement. The results are markedly influenced by the timing of the operation and the choice of the implant. Using the Garden classification of femoral neck fracture we demonstrate a different therapeutic approach according to Garden stadium I-IV.
- Published
- 2000
177. [Intrathoracic displacement of the transverse colon as a late complication after abdominal knife stab wound. A case report]
- Author
-
M, Wick, D, Martin, E J, Müller, and G, Muhr
- Subjects
Adult ,Male ,Radiography ,Thoracotomy ,Colon ,Humans ,Abdominal Injuries ,Wounds, Stab ,Respiratory Insufficiency ,Hernia, Diaphragmatic, Traumatic - Abstract
The treatment of stab wounds of the abdomen is discussed controversely. The management of these wounds depends on a high degree on the clinical situation of the patient. Repeated physical examination, peritoneal lavage and laparotomy are recommended. The identification of an isolated diaphragmatic injury is worrisome because its subtle clinical presentation is often not alleviated by adjunctive tests. Delayed recognition of an incarcerated diaphragmatic hernia has a high mortality rate. We report about an 23 year old African male, who was injured by an intraabdominal stab wound. Initially he did not have any clinical problems, but after 6 months he was admitted to the hospital due to severe pulmonary complications. A diaphragmatic hernia with dislocation of the transverse colon into the left thorax was identified on x-rays. A thoracotomy as well as a laparotomy were performed to restore the anatomic conditions and to dose the hernia. After two weeks, the patient could leave the hospital without pulmonary complications. Under consideration of the literature we recommend exploratory laparotomy for stab wounds that penetrate the left side of the chest below the fourth intercostal space anteriorly, the sixth intercostal space laterally and the tip of the scapula posteriorly. The high mortality rate after a delayed recognition appears to justify an early operative approach.
- Published
- 2000
178. [Comment on R. Smektala et al.: Femoral neck fracture: analysis of results of external quality assurance]
- Author
-
G, Muhr
- Subjects
Survival Rate ,Bias ,Quality Assurance, Health Care ,Germany ,Humans ,Length of Stay ,Femoral Neck Fractures ,Total Quality Management - Published
- 2000
179. [Ankle joint fractures in adults]
- Author
-
J, Richter and G, Muhr
- Subjects
Adult ,Fracture Healing ,Radiography ,Fracture Fixation, Internal ,Fractures, Bone ,Postoperative Complications ,Humans ,Ankle Injuries - Published
- 2000
180. [Reconstructive surgery of the cruciate ligament. How to achieve optimal results? The Indianapolis experience]
- Author
-
J, Richter and G, Muhr
- Subjects
Adult ,Male ,Arthroscopy ,Time Factors ,Athletic Injuries ,Ligaments, Articular ,Football ,Humans ,Female ,Basketball ,Knee Injuries ,Exercise Therapy ,Follow-Up Studies - Published
- 2000
181. [Anterior screw fixation for odontoid fractures]
- Author
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E J, Müller, M, Wick, O J, Russe, M, Palta, and G, Muhr
- Subjects
Adult ,Aged, 80 and over ,Male ,Adolescent ,Middle Aged ,Radiography ,Fracture Fixation, Internal ,Postoperative Complications ,Odontoid Process ,Humans ,Spinal Fractures ,Female ,Aged ,Follow-Up Studies - Abstract
The results of anterior screw fixation of odontoid fractures in 28 patients are presented. There were 27 type II- and 1 type III-injuries. Non-union with persistent instability had to be notified in one patient (3.6 %), secondary posterior C1/2 fusion had to be performed. Incorrect positioning of the screws in the odontoid with penetration of the postero-lateral cortex occurred in 3 patients (10.7 %). Malpositioning of the odontoid after screw fixation was documented in 5 cases (17.9 %). Cardiopulmonary complications had to be treated in 5 patients (17.9 %), 4 patients (14.3 %) died in the postoperative period. 17 patients could be followed up. Only 3 patients (17.8 %) were free of symptoms. A significant limitation in ROM of axial rotation was seen in 44 % of the patients. With anterior screw fixation of the odontoid high fusion rates can be achieved, however the procedure is technically demanding. Regarding the functional outcome, there is no significant difference to other established treatment methods.
- Published
- 2000
182. Qualitätsmanagement in Klinik und Forschung
- Author
-
C. J. E. Gekle and G. Muhr
- Published
- 2000
183. Effekte der Wechsellagerung in Abhängigkeit vom Therapiebeginn
- Author
-
M. Walz, G. Muhr, and G. Möllenhoff
- Abstract
Die wechselnde Bauch- und Ruckenlagerung hat in der Therapie des Lungenversagens an Bedeutung gewonnen. Wir unterscheiden die primare (Start innerhalb der ersten 36 Stunden nach Trauma, PA) von der spateren, sekundaren Anwendung (SA). Unterscheiden sich die Effekte in Abhangigkeit vom Therapiebeginn? Die Auswertung der Verlaufe von 304 Patienten (PA: n = 212, SA: n = 92) ergab fur die PA eine kurzere Anwendungsdauer (7.4 vs. 12.1 d) und eine niedrigere Mortalitat (9.4% vs. 18.5). Auch die Letalitat des ARDS war bei fruhzeitigem Therapiebeginn geringer (10.6% vs. 18.5%). In der PA-Gruppe zeigte sich eine mit 0.6% drastisch gesenkte Inzidenz des ARDS als wesentlichster Effekt. Die fruhzeitige, prophylaktische Anwendung der Wechsellagerung fuhrte zur rascheren Verbesserung der gestorten Oxygenierung und konnte bei Patienten mit initial noch nicht wesentlich beeintrachtigter Lungenfunktion eine Verschlechterung nahezu immer verhindern.
- Published
- 2000
184. Polytrauma (IV) - Immunologie / Entzündungsreaktion
- Author
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G. Muhr, T.A. Schildhauer, M. Köller, and M. P. Hahn
- Subjects
business.industry ,Anesthesia ,Medicine ,business ,medicine.disease ,Polytrauma - Published
- 2000
185. Experimentelle Unfallchirurgie I Wachstumsfaktoren - Grundlagenforschung
- Author
-
P. Klein, K. Weise, S. Assenmacher, G. Herr, T. Holzmann, R. Falk, M. van Griensven, A. Weiler, U. Pfister, S. Grässel, A. Probst, D. Höntzsch, G. Schmidmaier, U. Bosch, M. Amling, F. Högel, D. Nast-Kolb, C. Müller, H. J. Bail, M. Leunig, P. Reynders, F. Maurer, J. Fritz, A. Beck, G. Muhr, S. Hankemeier, A. F. Schilling, F. Gebhard, U. Schmid, L. Olivier, W. Strecker, P. Lobenhoffer, S. A. Esenwein, W. Hofstetter, R. Stange, R. Egli, G. Voggenreiter, N. P. Südkamp, S. Kolbeck, B. Wildemann, U. Holz, P. Bruckner, R. Peter, M. Priemel, L. Claes, L. Kinzl, C. Gaissmaier, S. Esenwein, M. Raschke, K. Raus, P. de Zwart, P. Broos, R. Ganz, C.-H. Hartwig, I. Roenne, C. Wingenfeld, M. Skutek, T. Krackhardt, J. Zeichen, C. Förster, J. M. Rueger, and C. F. Fraitzl
- Published
- 2000
186. Kindliche Femurschaftfraktur — Behandlung mit der elastischen Markraumschienung als Methode der Wahl?
- Author
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E. Kollig, S. A. Esenwein, F. Kutscha-Lissberg, and G. Muhr
- Abstract
Die Femurschaftfraktur des Kindesalters stellt eine haufige Verletzung vor. Wahrend die konservative Behandlung in den letzten Jahren erheblich an Bedeutung verloren hat, werden heute zunehmend operative Behandlungsformen favorisiert. Die offene Reposition mit der Plattenosteosynthese wie auch die geschlossene Einrichtung mit anschliesendem Fixateur externe gelten inzwischen nicht mehr als kindgerecht. Als Alternative ist die elastische Markraumschienung nach Prevot anzufuhren. In einem Dreijahreszeitraum wurden in unserer Institution 15 Kinder von 3 bis 14 Jahren mit einer Femurschaftfraktur mittels geschlossener Reposition und intramedullarer Stabilisierung durch elastische Titannagel versorgt (TEN). Eingeschlossen wurden auch die gelenknahen Schaftbruche. Eine kurzzeitige zusatzliche Gipsbehandlung wurde nur bei 2 huftnahen Bruchen angewandt.Alle Frakturen heilten im Durchschnitt innerhalb von 7 Wochen zur vollen Belastbarkeit aus.
- Published
- 2000
187. Postersession VI-Soft Tissue/Knorpel
- Author
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W. Schwarz, B. Friemert, Y. Oberländer, B. Danz, W. Bähren, H. Gerngroß, G. M. Maier, S. Weindel, R. Müller-Rath, S. Bolte, V. Maier, U. Mommsen, M. G. Baacke, R. Stiletto, R. Leppek, H. Bäthis, M. Tingart, B. Bouillon, A. Gaitzsch, T. Bogosi, G. Merényi, T. Atanaszov, S. Schubert, S. Piatek, T. Westphal, T. Bürger, S. Winckler, E. Scola, C. Simanski, G. Koch-Epping, T. Tiling, O. Rühmann, C. Wirth, F. Gossé, S. Schmolke, C. Dumont, P. Stanković, M. Fuchs, K. M. Stürmer, D. Jezussek, L. Kleine, O. Weber, A. Schmidgen, A. Wentzensen, A. F. Hinsche, J. Joseph, P. V. Giannoudis, S. J. Matthews, R. M. Smith, J. E. Mueller, T. Ilchmann, T. Lowatscheff, J. Sterk, H. U. Völker, C. Willy, P. Manak, P. Drac, T. Frebel, B. Leidinger, A. Joist, U. Joosten, P. Klever, U. P. F. Siekmann, H. J. Erli, C. Haltern, R. Rossaint, O. Paar, T. Niebauer, J. Gehr, W. Friedl, L. Tóth, J. Kovács, F. Fierpasz, G. Dósa, T. Radebold, J. Hensel, M. Bischoff, R. Grabensee, A. Schmelz, L. Kinzl, F. Huber, M. A. Scherer, G. Metak, S. v. Gumppenberg, T. Fuchs, G. Schmidmaier, J. E. Hoffmann, M. Raschke, A. Betthäuser, K. Raabe, E. Hille, T. Bickert, J. Folgmann, K. Kurten, C. Kühne, O. Klinger, L. Gotzen, M. Schnabel, M. Wenski, T. von Garrel, M. Förtsch, M. Prymka, R. Zeller, M. Schürmann, J. Zaspel, A. Wipfel, G. Gradl, C. Herzog, M. Bauer, M. G. Clemens, I. Marzi, W. Lehmann, W. Linhart, A. F. Schilling, K. Schwarz, M. Epple, J. M. Rueger, J. Blum, M. Högner, F. Baumgart, P. M. Rommens, M. Pszolla, P. Keppler, W. Strecker, C. Dollriess, E. Kollig, F. Hopf, G. Muhr, T. Henke, S. Gruber, J. Schmidt, K. H. Winker, J. Degreif, L. P. Müller, L. Rudig, A. Ewert, A. Scheller, C. Voigt, R. Rahmanzadeh, M. Kettler, S. Trageiser, R. Baumgart, W. Mutschler, K.-H. Frosch, A. Schmid, G. Altenvoerde, U. R. Schiefer, J. B. Nijs, P. L. O. Broos, D. Pape, E. Fritsch, A. Adam, D. Kohn, A. Thannheimer, R. Ketterl, S. Brüner, M. Wittemann, B. Karle, G. Germann, A. Gänsslen, T. Pohlemann, H. C. Pape, H. Tscherne, M. Grotz, U. Kaufmann, N. Danelia, B. W. Wippermann, L. Mahlke, M. Winny, H.-C. Pape, O. Gonschorek, D. Rüttinger, G. O. Hofmann, V. Bühren, U. C. Liener, U. B. Brückner, G. Steinbach, F. Gebhard, M. Rummeny, M. Fell, H. W. Kottkamp, A. Meißer, M. Sarkar, E. Billharz, J. Andermahr, H. J. Helling, T. Hensler, A. Greb, E. Neugebauer, K. E. Rehm, A.-M. Weinberg, R. Hawi, M. Jablonski, H. Hofmann, M. Zdichavsky, L. Bastian, C. Knop, U. Lange, J. Lotz, M. Blauth, O. Grün, T. Gössling, A. Müller-Heine, P. Schandelmaier, A. Halder, S. Drischmann, S. Ludwig, R. Kreusch-Brinker, A. Karl, M. Stumpf, F. Jonas, C. Neumann, M. Nerlich, J. Ohnsorge, D.-C. Wirtz, K. Birnbaum, K.-D. Heller, M. Langer, E. Ziring, B. Ishaque, J. Petermann, Z. Szabo, I. Barany, M. E. Chantes, D. Mastrokalos, C. O. Tibesku, H. H. Pässler, D. Jung, V. Matussek, P. Habermeyer, R. Meier, H. Thermann, H. E. Schratt, M. van Griensven, J. van Schoonhoven, T. Djalal, R. Freitag, D. Klüppel, B. Hillrichs, V. Echtermeyer, S. Marlovits, R. Stocker, V. Vécsei, R. S. Schabus, N. L. Ankin, L. N. Ankin, A. Schmeling, M. Kääb, R. Wieling, K. Ito, M. Schütz, O. A. Trentz, G. K. Uhlschmid, S. Weber, C. Graser, I. Fichtel, J. Schlegel, M. H. Hessmann, F. Geiger, C. Wendler, H. Forkl, H. J. Andress, R. Brüning, M. Grubwinkler, G. Lob, C. Weiβer, R. Wagner, A. Weckbach, M. Schädel-Höpfner, K. Giannadakis, J. Fröhlich, A. Dietrich, H. Lill, T. Engel, C. Josten, K. Richter, P. Verheyden, U. Martin, and M. Beckert
- Subjects
Chemistry ,Soft tissue ,Biomedical engineering - Published
- 2000
188. Therapie der ipsilateralen Femurfraktur bei einliegender Totalendoprothese
- Author
-
F.-X. Huber, P.-J. Meeder, J. Buchholz, L. Herzog, and G. Muhr
- Abstract
Wir untersuchten 102 Patienten (1981–1995) mit Femurfraktur bei ipsilateraler Huftgelenksendoprothese. 71 Patienten (Durchschnittsalter 65 Jahre) konnten im Schnitt 4,5 Jahre nach erfolgter Behandlung nachuntersucht werden. Die periprothetische Fraktur nach Huftgelenksendoprothese ist zwar eine auf die gesamte Zeit bezogene seltene, jedoch fur den betroffenen Patienten stets schwerwiegende Komplikation. Bei den Fraktur-typen A und B 1 stellten wir die Indikation zur konservativen Behandlung. Hauptindikation fr den Prothesenwechsel mit Ubergang auf die Revisionsprothetik stellt der Frakturtyp B 2 dar. Eindeutig empfehlen wir die Versorgung der Frakturtypen C bei fest verankerter Prothese mit einer Plattenosteosynthese und autologer Spongiosa. Im Falle der Lockerung sollte eine Explantation der Huftendoprothese und Implantation einer Revisionsprothese durchgefuhrt werden.
- Published
- 2000
189. 'Worst Case'Szenario-Salvage-Verfahren II
- Author
-
W. E. Mutschler, C. Zeiler, E.-H. Schwer, C. H. Siebert, F. U. Niethard, M. Weber, P. Brucker, A. Burkart, A. B. Imhoff, S. A. Esenwein, E. Kollig, K. Robert, T. Ambacher, F. Kutscha-Lissberg, G. Muhr, E. W. Kollig, C. Dollries, M. Bühler, B. Gilberger, M. Börner, F. Hopf, A. Pommer, and J. Richter
- Published
- 2000
190. Verbleibende Problemfrakturen II - Wirbelsäule - Becken
- Author
-
H. Scheele, T. Hüfner, I. Schwinnen, G. Muhr, U. Fischer, J. Lotz, E. Grabbe, M. Blauth, T. Pohlemann, C. Knop, F. Maurer, A. Gänsslen, K. S. Saternus, K. Weise, M. Bruett, M. Wick, M. Zdichavsky, I. Meyer, Ernst Josef Müller, M. Ueser, H.-W. Kuensebeck, L. Bastian, U. Lange, T. Lowatscheff, K. Hiersemann, K. Dresing, S. Zech, and C. Chylarecki
- Published
- 2000
191. Postersession I-Presträgersitzung
- Author
-
B. Füchtmeier, R. Hente, S. M. Perren, M. Nerlich, G. Krischak, S. Wolf, L. Kinzl, L. Claes, M. Achten, M. A. Scherer, W. Schwarz, H. Gerngroß, G. Metak, S. v. Gumppenberg, U. Mayr-Wohlfart, S. Kessler, R. Brenner, K. P. Günther, J. Ziegler, T. John, M. Shakibaei, P. deSouza, H.-J. Merker, R. Rahmanzadeh, A. Hofmann, C. Hofmann, F. Moischke, L. Konrad, L. Gotzen, B. Krapohl, M. Siemionow, J. E. Zins, H.-G. Machens, B. Reichert, P. Mailänder, C. Heiss, C. Meyer, J.-P. Stahl, R. Schnettler, L. J. Capeller, C. Föster, C. von Fournier, N. P. Südkamp, M. P. Palm, L. Zwank, M. Schädel-Höpfner, G. Böhringer, M. H. Hessmann, H. Gehling, F. Baumgaertel, Ch. Meyer, E. Markgraf, R. H. Meffert, N. Inoue, E. McCarthy, E. Brug, E. Y. S. Chao, P. Kasten, B. Schewe, F. Maurer, K. Weise, A. Betthäuser, T. Kruppa, C. Bartram, E. Hille, T. A. Friess, C. Bahrs, R. Leppeck, C. Fleischhacker, M. Schnabel, M. Mehlis, M. Kleinheyer, M. Wennmacher, A. Meißner, M. Burrer, T. Harms, B. Wittner, U. Holz, M. Rahmanzadeh, K. Ipaktchi, S. Piatek, T. Westphal, S. Schubert, S. Winckler, A. Mohr, E. Schneider, C. Dorow, S. Rausch, M. Oberst, H. Stöltzing, K.-P. Thon, E. Schäfer, R. Stiletto, M. Baacke, M. Kalt, L. Knipping, H. Schmelzeisen, T. Nau, F. Kutscha, T. Müllner, V. Vècsei, H. Dorow, T. Hohaus, R. Cyffka, T. Lein, D. Paul, A. Blocks, B. Friemert, W. Kauffels, K. Mühlhaus, B. Wippermann, C. Hauke, P. Hoffmeyer, G. Vatter, W. K. Zychlinski, W. Marczynski, J. Gawlikowski, S. Tuschen, K. Niess, H. Trouillier, B. Hintermann, G. Suveges, E. Varga, J. A. Simonka, Z. Balogh, A. Horvath, M. Fuchs, H. Burchhardt, K. M. Stürmer, K. Fischer, E.-J. Müller, G. Muhr, U. Moorahrend, W. H. M. Castro, E. Hartwig, W. Hell, O. Pieske, U. Thoden, E. Scola, D. Jezussek, L. Kleine, A. Krueger, A. Junge, J. Petermann, C. Gekle, E. J. Müller, M. Wick, C. Kleinhorst, M. Fell, M. Schierlinger, T. J. Henke, L. Eschbach, M. Portmann, P. Steiger, R. Frigg, M. Spieß, T. von Garrel, C. Heiß, S. Marchetti, M. Manca, M. Phillips, M. Iacopinelli, A. Faldini, R. Schwyn, M. Hehli, J. Alonso, A. Fernandez Dell’ Oca, P. Messmer, P. Regazzoni, M. Reuter, M. Holch, U. Aschenbrenner, H. Zwipp, J. Iwinska-Zelder, N. Ishaque, H. P. Kerling, M. Barthel, S. Toth, H. Halsband, T. Pesl, A. Gänsslen, T. Pohlemann, T. Hüfner, H. C. Pape, M. Tingart, J. Höher, H. Bäthis, and T. Tiling
- Published
- 2000
192. Luxationsfrakturen des Ellenbogens mit Beteiligung des Processus coronoideus
- Author
-
T. Kälicke, T. Ambacher, S. Arens, M. P. Hahn, and G. Muhr
- Published
- 2000
193. Mortalität nach hüftgelenksnaher Fraktur
- Author
-
G. Meng, G. Muhr, J. Buchholz, P.-J. Meeder, and L. Herzog
- Abstract
Wir untersuchten prospektiv, randomisiert und doppelblind 932 Patienten (durchschnittlich 81,4 Jahre) mit huftgelenksnahen Frakturen (Multicenterstudie). Einschluskriterien waren z. B. Alter > 65 Jahre, operative Versorgung innerhalb 48 Stunden und weitgehende organische Integritat. Ausschluskriterien waren z. B. pathologische Frakturen. Die Mortalitat innerhalb 21 Tage nach Fraktur Verstorbenen wurden analysiert. 134 (14,4%) Patienten verstarben, davon 37 innerhalb der ersten 21 Tage. 8,9% aller Patienten wiesen eine ernsthafte, nichtfrakturbezogene Komplikation auf gegenuber 37,9% der verstorbenen Patienten (frakturbezogene Komplikationen demgegenuber 8,9% bzw.10,6%). Die Patienten dieser Studie verstarben an bestehenden Vorerkrankungen; bereits eine postoperative Komplikation fuhrt zur Dekompensation. Die Mortalitat konnte wahrend der Studie von 25 auf 14,4% gesenkt werden; weitere Verbesserungen sind lediglich durch Einrichtung einer interdisziplinaren HIP-Unit zu erwarten.
- Published
- 2000
194. Innovation I - Die am besten beurteilten Innovationsbeiträge
- Author
-
G. Muhr, Ernst Wiedemann, Thomas Mussack, L. Konrad, Ch. Hofmann, H.-J. Kock, C. Gippner-Steppert, P. Biberthaler, Peter R. Mueller, A. L. Jacob, Norbert Suhm, L. Claes, M. Hehli, T. Aigner, R. Wenz, J.-P. Stahl, G. Herr, M. Heller, Marianne Jochum, U. Horas, G. Möllenhoff, P. Regazzoni, B. Nies, A. K. Vocke, G. Schmeiser, R. Schnettler, Peter Pokinskyj, M. Walz, F. Moischke, Reinhard Putz, G. N. Duda, N. P. Haas, G. Bergmann, L. v. Laer, H. Hempfling, G. Deuretzbacher, P. Messmer, L. Gotzen, A. Hofmann, J. Blum, W. Mutschler, P. M. Rommens, C. C. Hasler, and V. Bühren
- Subjects
Materials science - Published
- 2000
195. Sprungelenksbänder - Verletzung / Insuffizienz
- Author
-
G. Muhr, J. Richter, and S. Esenwein
- Published
- 2000
196. Alterstraumatologie III
- Author
-
C. Dumont, M. Fuchs, K. Dresing, K. M. Stürmer, U. Joosten, T. Frebel, M. Langer, A. Joist, S. Kluge, M. Sauerbier, B. Bickert, G. Germann, G. Fischer, R. Engel, J. Brzezinski, R. Schulz, M. Grotz, H. C. Pape, H. Baur, H. Tscherne, J. Korner, H. Lill, T. Amtmann, D. Schreiter, C. Josten, D. Brilej, B. Buhanec, M. Vlaoviæ, R. Komadina, I. Schwinnen, E. J. Müller, K. Fischer, G. Muhr, L. Kleinschmidt, R. Hierner, U. Rhode, and A. Berger
- Published
- 2000
197. [Surgical, conservative and functional fracture treatment]
- Author
-
G, Muhr
- Subjects
Fracture Healing ,Casts, Surgical ,Fracture Fixation, Internal ,Fractures, Bone ,Treatment Outcome ,Splints ,Humans - Published
- 1999
198. [Hierarchy in surgery. An antiquated system?]
- Author
-
G, Muhr
- Subjects
Physician Executives ,General Surgery ,Germany ,Humans ,Curriculum ,Hierarchy, Social - Abstract
Medical responsibility and hospital management, competency for resident's training and decision making in therapy are better performed in a system of hierarchy than other kinds of organisation of a surgical department. If all the duties and responsibilities are concentrated to a head of the department, it is also necessary to give him the adequate instruments for leadership, to stay alive.
- Published
- 1999
199. [Results of posttraumatic elbow arthrolyses: a prospective study]
- Author
-
L U, Lahoda, T, Klapperich, M P, Hahn, and G, Muhr
- Subjects
Adult ,Male ,Postoperative Care ,Reoperation ,Adolescent ,Ankylosis ,Middle Aged ,Radiography ,Treatment Outcome ,Elbow Joint ,Humans ,Female ,Range of Motion, Articular ,Child ,Elbow Injuries ,Aged - Abstract
Posttraumatic stiffened joints are mostly well restored by means of operation, however, the range of motion remains restricted by secondary soft tissue shrinking and scarring. Conservative treatment yields only limited success rates. Open arthrolysis is a useful tool in regaining function; in postoperative treatment, immediate passive mobilization and prevention of heterotopic ossification are most important.Sixty-nine patients were arthrolyzed on average 25.3 months post trauma, with an average of 1.5 previous operations (range 0-8) and a follow-up period of 14.7 months.By means of the open arthrolysis, an increase in range of motion for flexion and extension of 62.3 degrees (preoperative 38.4 degrees, postoperative 87.9 degrees, at follow-up 100.7 degrees ) and 29.3 degrees for pro- and supination was achieved on average. The highly important range of motion between 0-30 degrees and 110 degrees was accomplished in 78.2 % of the patients. We analyzed the postoperative management including irradiation, pharmacological ossification prophylaxis with indomethacin and immediate passive motion. Whenever the time to arthrolysis exceeded 9 months, clearly worse results were obtained, thus we measured a difference in the correlated increase of motion from 54.3 % - 34.6 %. Comparisons of our results with German (after Blauth and Hipp) and French (after Cauchoix and Deburge) standard follow-up forms are made, and the rehabilitation program is underlined and explained. Another task of this study was to discuss the complication rate.
- Published
- 1999
200. [Pediatric forearm fractures: indications, technique, and limits of conservative management]
- Author
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P A, Ostermann, D, Richter, K, Mecklenburg, A, Ekkernkamp, G, Muhr, and M P, Hahn
- Subjects
Fracture Healing ,Male ,Adolescent ,Forearm Injuries ,Infant ,Bone Malalignment ,Radiography ,Fractures, Bone ,Treatment Outcome ,Child, Preschool ,Humans ,Female ,Child ,Follow-Up Studies - Abstract
Although several "minimal invasive" techniques for the operative management of pediatric forearm fractures have been developed recently, conservative treatment still remains the option with the lowest risk for small patients. We present the results of our clinical and radiological follow-up after an average of 52.4 months (4-112) in 102 pediatric patients. All fractures were treated conservatively. There were 68 fractures (66.7 %) of the distal third of the forearm, 30 fractures (29.4 %) of the midshaft area, and four fractures (3.9 %) in the proximal third of the shaft. Greenstick fractures were seen in 58 cases (56.8 %), complete fractures with displacement of both corticalices in 26 patients (25.5 %), and folding fractures in 18 cases (17.7 %). With the exception of one fracture with the necessity of remanipulation after redisplacement in the cast, all fractures healed uneventfully without any further intervention. Functional results were excellent with a free range of motion of the wrist and elbow and without any signs of muscular atrophy in 96 children (94.1 %) at the time of follow-up. Six patients, however, showed a significant loss of forearm rotation of an average of 25 degrees (15 degrees -50 degrees ). In four of these six patients, the fracture had been situated in the proximal and midshaft area. Thus, two out of four fractures of the proximal forearm (50.0 %) showed a poor functional outcome. On the basis of our data we recommend conservative management for (closed) pediatric fractures of the distal and midshaft area. Operative treatment is indicated in forearm fractures close to the elbow.
- Published
- 1999
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