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153. Patient engagement in preclinical laboratory research: A scoping review

Author

Fox, Grace, primary, Fergusson, Dean A., additional, Daham, Zeinab, additional, Youssef, Mark, additional, Foster, Madison, additional, Poole, Evelyn, additional, Sharif, Ayni, additional, Richards, Dawn P., additional, Hendrick, Kathryn, additional, Mendelson, Asher A., additional, Macala, Kimberly F., additional, Monfaredi, Zarah, additional, Montroy, Joshua, additional, Fiest, Kirsten M., additional, Presseau, Justin, additional, and Lalu, Manoj M., additional

Published
2021
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156. Impact des politiques de visites restreintes pendant la COVID-19 sur les adultes gravement malades, leurs familles, les intensivistes et les décideurs : une étude d’entrevue qualitative.

Author

Fiest, Kirsten M., Krewulak, Karla D., Jaworska, Natalia, Spence, Krista L., Mizen, Sara J., Bagshaw, Sean M., Burns, Karen E. A., Cook, Deborah J., Fowler, Robert A., Olafson, Kendiss, Patten, Scott B., Rewa, Oleksa G., Rochwerg, Bram, Spence, Sean, West, Andrew, Stelfox, Henry T., Parsons Leigh, Jeanna, and Canadian Critical Care Trials Group

Abstract

Copyright of Canadian Journal of Anaesthesia / Journal Canadien d'Anesthésie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2022
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157. Factors associated with high health care spending among patients with schizophrenia.

Author

Stewart, Andrew J., Patten, Scott B., Fiest, Kirsten M., Williamson, Tyler S., Wick, James P., and Ronksley, Paul E.

Subjects
SCHIZOPHRENIA treatment, PUBLIC spending, MEDICAL care costs, POLYPHARMACY, MEDICAL care
Abstract

Introduction: Understanding the reasons for the wide variation in health care spending among patients with schizophrenia may benefit the development of interventions aimed at improving patient outcomes and health care spending efficiency. The aim of our study was to determine factors associated with high health care spending in the patient population. Methods: A serial cross-sectional study used the administrative health records of residents of Alberta, Canada between 1 January 2008 and 31 December 2017 and provincial costing methodologies to calculate total health care spending and sector-specific costs. Factors that modified the odds of being a high cost (i.e. 95th percentile or higher) patient with schizophrenia were estimated using generalized estimating equations. Results: This study captured 242 818 person-years of observations among 38 177 unique patients with schizophrenia. Increased odds of being a high-cost patient were associated with younger age (18-29 years), male sex, unstable housing status and requiring care from multiple medical specialties. The strongest estimated associations between high cost status and comorbidity were for metastatic cancer (OR = 2.26) and cirrhosis (OR = 2.07). In contrast, polypharmacy was associated with a decreased odds of being high cost compared with untreated patients. Conclusion: Factors associated with being a high-cost patient are the result of complex interactions between individual, structural and treatment-related factors. Efforts to improve patient outcomes and address rising health care costs must consider the value of allocating resources towards early detection and support of patients with schizophrenia along with the prevention/management of comorbidity. [ABSTRACT FROM AUTHOR]

Published
2022
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158. Patient, Public, and Healthcare Professionals' Sepsis Awareness, Knowledge, and Information Seeking Behaviors: A Scoping Review.

Author

Fiest, Kirsten M., Krewulak, Karla D., Brundin-Mather, Rebecca, Leia, Madison P., Fox-Robichaud, Alison, Lamontagne, François, Leigh, Jeanna Parsons, and for Sepsis Canada

Subjects
*MEDICAL personnel, *INFORMATION-seeking behavior, *SEPSIS, *EMERGENCY medical technicians, *AWARENESS, *SYSTEMATIC reviews, *MEDICAL care, *JOB Descriptive Index, *QUESTIONNAIRES, *RESEARCH funding, *LITERATURE reviews
Abstract

Objectives: Sepsis awareness and understanding are important aspects of prevention, recognition, and clinical management of sepsis. We conducted a scoping review to identify and map the literature related to sepsis awareness, general knowledge, and information-seeking behaviors with a goal to inform future sepsis research and knowledge translation campaigns.Design: Scoping review.Setting: Using Arksey and O'Malley's methodological framework, we conducted a systematic search on May 3, 2021, across four databases (MEDLINE, EMBASE, CINAHL, and Education Research Complete). Title/abstract and full-text screening was done in duplicate. One researcher extracted the data for each included article, and a second researcher checked data accuracy. The protocol was registered on Open Science Framework ( https://doi.org/10.17605/OSF.IO/YX7AU ).Subjects: Articles related to sepsis awareness, knowledge, and information seeking behaviors among patients, public, and healthcare professionals.Interventions: None.Measurements and Main Results: Of 5,927 unique studies, 80 reported on patient ( n = 13/80;16.3%), public ( n = 15/80;18.8%), or healthcare professional (nurses, physicians, emergency medical technicians) ( n = 48/80; 60%) awareness and knowledge of sepsis. Healthcare professional awareness and knowledge of sepsis is high compared with patients/public. The proportion of patients/public who had heard of the term sepsis ranged from 2% (Japan) to 88.6% (Germany). The proportions of patients/public who correctly identified the definition of sepsis ranged from 4.2% (Singapore) to 92% (Sweden). The results from the included studies appear to suggest that patient/public awareness of sepsis gradually improved over time. We found that the definition of sepsis was inconsistent in the literature and that few studies reported on patient, public, or healthcare professional knowledge of sepsis risk factors. Most patient/public get their sepsis information from the internet, whereas healthcare professionals get it from their role in healthcare through job training or educational training.Conclusions: Patient, public, and healthcare professional awareness and knowledge of sepsis vary globally. Future research may benefit from a consistent definition as well as country-specific data to support targeted public awareness campaigns. [ABSTRACT FROM AUTHOR]

Published
2022
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159. The Effects of Biological Sex on Sepsis Treatments in Animal Models: A Systematic Review and a Narrative Elaboration on Sex- and Gender-Dependent Differences in Sepsis

Author

Zhang, MengQi, primary, Montroy, Joshua, additional, Sharma, Rahul, additional, Fergusson, Dean A., additional, Mendelson, Asher A., additional, Macala, Kimberly F., additional, Bourque, Stephane L., additional, Schlechte, Jared M., additional, Eng, Mikaela K., additional, McDonald, Braedon, additional, Gill, Sean E., additional, Fiest, Kirsten M., additional, Liaw, Patricia C., additional, Fox-Robichaud, Alison, additional, and Lalu, Manoj M., additional

Published
2021
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162. Additional file 1 of Adverse events associated with administration of vasopressor medications through a peripheral intravenous catheter: a systematic review and meta-analysis

Author

Owen, Victoria S., Rosgen, Brianna K., Stephana J. Cherak, Ferland, Andre, Stelfox, Henry T., Fiest, Kirsten M., and Niven, Daniel J.

Subjects
endocrine system, hormones, hormone substitutes, and hormone antagonists
Abstract

Additional file 1. Table S1: MEDLINE search strategy. Table S2: Conference abstracts searched. Table S3: Demographic and clinical characteristics of patients who received peripheral intravenous vasopressors. Table S4: Adverse event characteristics. Table S5: Revised Cochrane risk-of-bias tool for randomized trials (RoB 2). Table S6: JBI Critical Appraisal Checklist for Studies Reporting Prevalence Data. Fig. S1: Funnel plot of studies included in the meta-analysis. Fig. S2: Forest plot examining the incidence proportion of adverse events associated with peripheral intravenous vasopressor administration of adult studies stratified by location of care. Fig. S3: Forest plot examining the incidence proportion of adverse events associated with peripheral intravenous vasopressor administration of Adult studies stratified by study design. Fig. S4: Forest plot examining the incidence proportion of adverse events associated with peripheral intravenous vasopressor administration of adult studies stratified by the mean/median duration of infusion. Fig. S5: Forest plot examining the incidence proportion of adverse events associated with peripheral intravenous vasopressor administration of adult studies stratified by Intravenous gauge. Fig. S6: Forest plot examining the incidence proportion of adverse events associated with peripheral intravenous vasopressor administration of Adult studies stratified by anatomical location. Fig. S7: Forest plot examining the incidence proportion of adverse events associated with peripheral intravenous vasopressor administration of adult studies stratified by vasopressor type. Fig. S8: Forest plot examining the incidence proportion of adverse events associated with peripheral intravenous vasopressor administration of adult studies stratified by patient sex. Fig. S9: Sensitivity analysis of forest plot examining the incidence proportion of adverse events associated with peripheral intravenous vasopressor administration in adults.

Published
2021
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163. Additional file 2 of Patient discharge from intensive care: an updated scoping review to identify tools and practices to inform high-quality care

Author

Plotnikoff, Kara M., Krewulak, Karla D., Hern��ndez, Laura, Spence, Krista, Foster, Nadine, Longmore, Shelly, Straus, Sharon E., Niven, Daniel J., Parsons Leigh, Jeanna, Stelfox, Henry T., and Fiest, Kirsten M.

Subjects
ComputingMethodologies_PATTERNRECOGNITION, InformationSystems_INFORMATIONSTORAGEANDRETRIEVAL, Data_FILES
Abstract

Additional file 2. MEDLINE Search Strategy

Published
2021
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164. Additional file 4 of Patient discharge from intensive care: an updated scoping review to identify tools and practices to inform high-quality care

Author

Plotnikoff, Kara M., Krewulak, Karla D., Hern��ndez, Laura, Spence, Krista, Foster, Nadine, Longmore, Shelly, Straus, Sharon E., Niven, Daniel J., Parsons Leigh, Jeanna, Stelfox, Henry T., and Fiest, Kirsten M.

Abstract

Additional file 4. Article classification according to study population, describing framework elements, themes, and facilitators and barriers

Published
2021
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165. Additional file 2 of Incorporating and evaluating citizen engagement in health research: a scoping review protocol

Author

Shahid, Anmol, Rosgen, Brianna K., Krewulak, Karla D., Lorenzetti, Diane L., Foster, Nadine, Sept, Bonnie G., Leigh, Jeanna Parsons, Stelfox, Henry T., and Fiest, Kirsten M.

Subjects
ComputingMethodologies_PATTERNRECOGNITION, InformationSystems_INFORMATIONSTORAGEANDRETRIEVAL, Data_FILES
Abstract

Additional file 2:. Medline Search Strategy

Published
2021
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167. Additional file 1 of Patient discharge from intensive care: an updated scoping review to identify tools and practices to inform high-quality care

Author

Plotnikoff, Kara M., Krewulak, Karla D., Hern��ndez, Laura, Spence, Krista, Foster, Nadine, Longmore, Shelly, Straus, Sharon E., Niven, Daniel J., Parsons Leigh, Jeanna, Stelfox, Henry T., and Fiest, Kirsten M.

Abstract

Additional file 1. Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) Checklist

Published
2021
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168. Additional file 3 of Patient discharge from intensive care: an updated scoping review to identify tools and practices to inform high-quality care

Author

Plotnikoff, Kara M., Krewulak, Karla D., Hern��ndez, Laura, Spence, Krista, Foster, Nadine, Longmore, Shelly, Straus, Sharon E., Niven, Daniel J., Parsons Leigh, Jeanna, Stelfox, Henry T., and Fiest, Kirsten M.

Subjects
health care facilities, manpower, and services
Abstract

Additional file 3. Tools to facilitate a successful ICU discharge

Published
2021
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171. Additional file 1 of Restricted visitation policies in acute care settings during the COVID-19 pandemic: a scoping review

Author

Moss, Stephana J., Krewulak, Karla D., Stelfox, Henry T., Ahmed, Sofia B., Anglin, Melanie C., Bagshaw, Sean M., Burns, Karen E. A., Cook, Deborah J., Doig, Christopher J., Fox-Robichaud, Alison, Fowler, Robert, Hernández, Laura, Kho, Michelle E., Kredentser, Maia, Makuk, Kira, Murthy, Srinivas, Niven, Daniel J., Olafson, Kendiss, Parhar, Ken Kuljit S., Patten, Scott B., Rewa, Oleksa G., Rochwerg, Bram, Sept, Bonnie, Soo, Andrea, Spence, Krista, Spence, Sean, Straus, Sharon, West, Andrew, Parsons Leigh, Jeanna, and Fiest, Kirsten M.

Abstract

Additional file 1. Supplementary material to “Restricted visitation policies in acute care settings during the COVID-19 pandemic: a scoping review”.

Published
2021
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178. Additional file 2 of Association between delirium in the intensive care unit and subsequent neuropsychiatric disorders

Author

Brown, Kyla N., Soo, Andrea, Faris, Peter, Patten, Scott B., Fiest, Kirsten M., and Stelfox, Henry T.

Abstract

Additional file 2. Characteristics of Those With and Without Pre-Existing Neuropsychiatric Disorders. The data presented in additional file 2 compare characteristics of patients with and without pre-existing neuropsychiatric disorders from five years prior to ICU admission.

Published
2020
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179. Additional file 3 of Association between delirium in the intensive care unit and subsequent neuropsychiatric disorders

Author

Brown, Kyla N., Soo, Andrea, Faris, Peter, Patten, Scott B., Fiest, Kirsten M., and Stelfox, Henry T.

Subjects
mental disorders, behavioral disciplines and activities, nervous system diseases
Abstract

Additional file 3. Unadjusted Risk Ratios for Delirium, Patient Characteristics and Neuropsychiatric Disorders. The data presented in additional file 3 present detailed unadjusted risk ratios for delirium, patient characteristics and each neuropsychiatric disorder.

Published
2020
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180. Additional file 1 of Allocation of intensive care resources during an infectious disease outbreak: a rapid review to inform practice

Author

Fiest, Kirsten M., Krewulak, Karla D., Plotnikoff, Kara M., Laryssa G. Kemp, Parhar, Ken Kuljit S., Niven, Daniel J., Kortbeek, John B., Stelfox, Henry T., and Leigh, Jeanna Parsons

Abstract

Additional file 1: Supplementary Appendix 1. (PRISMA checklist for systematic reviews), Supplementary Appendix 2. (MEDLINE search strategy), Supplementary Table 1. (Study characteristics), Supplementary Table 2. (Triage protocols based on an algorithm or point-based method), Supplementary Table 3. (Diagnostic accuracies of triage criteria), and Supplementary Table 4. (Ethical frameworks or guiding principles for triage decisions during a pandemic).

Published
2020
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181. Additional file 5 of Association between delirium in the intensive care unit and subsequent neuropsychiatric disorders

Author

Brown, Kyla N., Soo, Andrea, Faris, Peter, Patten, Scott B., Fiest, Kirsten M., and Stelfox, Henry T.

Abstract

Additional file 5. Sensitivity Analyses Between Delirium and No Delirium/one calendar day/two or more calendar days of Delirium in the Intensive Care Unit. The data presented in additional file 5 is the outputs of a sensitivity analysis between delirium and no delirium/one calendar day/two or more calendar days of delirium in the ICU.

Published
2020
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182. Additional file 4 of Association between delirium in the intensive care unit and subsequent neuropsychiatric disorders

Author

Brown, Kyla N., Soo, Andrea, Faris, Peter, Patten, Scott B., Fiest, Kirsten M., and Stelfox, Henry T.

Subjects
mental disorders, behavioral disciplines and activities, nervous system diseases
Abstract

Additional file 4. Adjusted Models for Delirium and Neuropsychiatric Disorders. The data presented in additional file 4 present detailed models for delirium and each neuropsychiatric disorder.

Published
2020
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183. Additional file 1 of Association between delirium in the intensive care unit and subsequent neuropsychiatric disorders

Author

Brown, Kyla N., Soo, Andrea, Faris, Peter, Patten, Scott B., Fiest, Kirsten M., and Stelfox, Henry T.

Abstract

Additional file 1. Frequency of Diagnostic Codes for Each Neuropsychiatric Disorder Per Visit Per Database for All Patient Data.: The data presented in additional file 1 present frequency of diagnostic codes for each neuropsychiatric disorder per visit per database (DAD, NACRS, and Physician Claims) for all patient data.

Published
2020
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184. Characteristics and outcomes of patients with COVID-19 admitted to hospital and intensive care in the first phase of the pandemic in Canada: a national cohort study

Author

Murthy, Srinivas, primary, Archambault, Patrick M., additional, Atique, Anika, additional, Carrier, François Martin, additional, Cheng, Matthew P., additional, Codan, Cassidy, additional, Daneman, Nick, additional, Dechert, William, additional, Douglas, Sarah, additional, Fiest, Kirsten M., additional, Fowler, Robert, additional, Goco, Geraldine, additional, Gu, Yusing, additional, Guerguerian, Anne-Marie, additional, Hall, Richard, additional, Hsu, Jimmy M., additional, Joffe, Ari, additional, Jouvet, Philippe, additional, Kelly, Laurel, additional, Kho, Michelle E., additional, Kruisselbrink, Rebecca J., additional, Kumar, Deepali, additional, Kutsogiannis, Demetrios James, additional, Lamontagne, François, additional, Lee, Todd C., additional, Menon, Kusum, additional, O’Grady, Heather, additional, O’Hearn, Katie, additional, Ovakim, Daniel H., additional, Pharand, Scott G., additional, Pitre, Tyler, additional, Reel, Riley, additional, Reeve, Brenda, additional, Rewa, Oleksa, additional, Richardson, David, additional, Rishu, Asgar, additional, Sandhu, Gyan, additional, Sarfo-Mensah, Shirley, additional, Shadowitz, Ellen, additional, Sligl, Wendy, additional, Solomon, Joshua, additional, Stelfox, Henry T., additional, Swanson, Ashleigh, additional, Tessier-Grenier, Hubert, additional, Tsang, Jennifer L.Y., additional, and Wood, Gordon, additional

Published
2021
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186. Standardized Management for Hypoxemic Respiratory Failure and ARDS

Author

Parhar, Ken Kuljit S., primary, Stelfox, Henry T., additional, Fiest, Kirsten M., additional, Rubenfeld, Gordon D., additional, Zuege, Danny J., additional, Knight, Gwen, additional, Lee Robertson, Helen, additional, Soo, Andrea, additional, Doig, Christopher J., additional, and Niven, Daniel J., additional

Published
2020
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187. Patients, family members and providers perceive family-administered delirium detection tools in the adult ICU as feasible and of value to patient care and family member coping: a qualitative focus group study

Author

Parsons Leigh, Jeanna, primary, Krewulak, Karla D., additional, Zepeda, Nubia, additional, Farrier, Christian E., additional, Spence, Krista L., additional, Davidson, Judy E., additional, Stelfox, Henry T., additional, and Fiest, Kirsten M., additional

Published
2020
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191. Impact of restricted visitation policies during COVID-19 on critically ill adults, their families, critical care clinicians, and decision-makers: a qualitative interview study

Author

Fiest, Kirsten M., Krewulak, Karla D., Jaworska, Natalia, Spence, Krista L., Mizen, Sara J., Bagshaw, Sean M., Burns, Karen E. A., Cook, Deborah J., Fowler, Robert A., Olafson, Kendiss, Patten, Scott B., Rewa, Oleksa G., Rochwerg, Bram, Spence, Sean, West, Andrew, Stelfox, Henry T., and Parsons Leigh, Jeanna

Abstract

Purpose: During the first wave of the COVID-19 pandemic, restricted visitation policies were enacted at acute care facilities to reduce the spread of COVID-19 and conserve personal protective equipment. In this study, we aimed to describe the impact of restricted visitation policies on critically ill patients, families, critical care clinicians, and decision-makers; highlight the challenges faced in translating these policies into practice; and delineate strategies to mitigate their effects. Method: A qualitative description design was used. We conducted semistructured interviews with critically ill adult patients and their family members, critical care clinicians, and decision-makers (i.e., policy makers or enforcers) affected by restricted visitation policies. We transcribed semistructured interviews verbatim and analyzed the transcripts using inductive thematic analysis. Results: Three patients, eight family members, 30 clinicians (13 physicians, 17 nurses from 23 Canadian intensive care units [ICUs]), and three decision-makers participated in interviews. Thematic analysis was used to identify five themes: 1) acceptance of restricted visitation (e.g., accepting with concerns); 2) impact of restricted visitation (e.g., ethical challenges, moral distress, patients dying alone, intensified workload); 3) trust in the healthcare system during the pandemic (e.g., mistrust of clinical team); 4) modes of communication (e.g., communication using virtual platforms); and 5) impact of policy implementation on clinical practice (e.g., frequent changes and inconsistent implementation). Conclusions: Restricted visitation policies across ICUs during the COVID-19 pandemic negatively affected critically ill patients and their families, critical care clinicians, and decision-makers.

Published
2022
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193. The authors reply

Author

Fiest, Kirsten M., primary, Krewulak, Karla D., additional, Sept, Bonnie G., additional, and Stelfox, Henry T., additional

Published
2020
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