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The article described a little-studied aspect of Soviet military construction in Siberia at the final stage of the Civil War in Russia — the creation and the first months of the activity of the Siberian Directorate of Military Educational Institutions of the Red Army. The source base of the study is unpublished materials of the office work of Siberian Revolutionary Committee, the Omsk press and memoirs. The theoretical basis of the study is a combination of anthropological and systemic approaches, problem-chronological, comparative-historical and biographical methods. The author comes to the conclusion about the key role of the Soviet military leaders M. N. Tukhachevsky and N. I. Koritsky in the formation of a network of military schools in Siberia, and the influence of the Siberian Directorate of Military Educational Institutions on the development of military education in the region and the cultural level of the local population.

The article is devoted to the characteristics of the socio-cultural image of the Tatar rural settlements of the Tobolsk province population at the beginning of the 20th century. The dynamics of the population and the number of settlements for the second half of the 19th — early 20th centuries are traced (according to the lists of settlements in the Tobolsk province). The authors focus on the consideration of the socio-cultural infrastructure of the Tatar rural settlements. It is understood as a set of objects of the non-productive sphere (religious, educational institutions, healthcare facilities and communications). They reveal regional and ethnic features of the integration of the Tatar population into the all-Russian system in the period under review. The country has undergone reforms aimed at unifying the management system and actively integrating the national outskirts into national processes. There was an acceleration of migration processes. It caused a violation of the former isolation of the rural Tatar-Muslim communities. Settlers arriving in the region contributed to the active development of commodity-money relations. The educational and cultural needs of the Tatar population grew. All-Russian processes have caused the need to adapt to new realities, in connection with which there is a modernization within the confessional education system.

The question of whether an artificial moral agent (AMA) is possible implies discussion of a whole range of problems raised by Kant within the framework of practical philosophy that have not exhausted their heuris­tic potential to this day. First, I show the significance of the correlation between moral law and freedom. Since a rational being believes that his/her will is independent of external influences, the will turns out to be governed by the moral law and is autonomous. Morality and freedom are correlated through independence from the external. Accordingly, if the actions of artificial intelligence (AI) are determined by something or someone external to it (by a human), then it does not act morally and freely, but heteronomously. As a consequence of AI’s lack of autonomy, and thus lack of access to the moral law, it does not and cannot have a moral understanding that proceeds from the moral law. Another consequence is that it has no sense of duty, which would follow from the moral law. Thus, moral action becomes impossible for the AMA because it lacks autonomy and moral law, moral understanding and sense of duty. It is concluded that, first, AMA not only cannot be moral, but should not be that, since the inclusion of any moral principle would imply the necessity for the individual to choose it, making the choice of the principle itself immoral. Second, although AI has no will as such, which prima facie makes not only moral but also legal action impossible, it can still act legally in the sense of conforming to legal law, since AI carries a quasi-human will. Thus, it is necessary that the creation of AI should be based not on moral principles, but on legal law that prioritises human freedom and rights.

The construction industry is a critical sector in the nation’s economic growth, accounting for a sizable share of GDP growth. However, it is the most vulnerable industry to a financial depression, whether local or worldwide. The present economic crisis has had an impact on the Sri Lankan construction industry, with more than half a million employees lost their jobs in the previous year. Many major construction firms have either paused or abandoned their projects and shifted to overseas construction. Therefore, understanding the consequences of financial crises regarding construction initiatives in Sri Lanka, as well as anticipated post-crisis growth paths in this sector, necessitates a thorough examination. The goal of this study is to extensively examine the consequences of the 2022 economic crisis on Sri Lankan construction projects and investigate remedies that might start a post-crisis rebound. The study utilized a mixed-method approach, combining quantitative and qualitative research methods. Purposive sampling was used to choose construction industry participants from various backgrounds in order to get a varied range of perspectives. The findings of this study not only emphasize the negative consequences of the crisis but also reveal prospects for development within the industry. The article offers construction professionals and other industry stakeholders useful insights about the foreseeable future of the country’s construction sector. The research looks at prospective growth areas such as the development of infrastructure, sustainable construction strategies, and the usage of emerging technology. The findings of the research can help to ensure that the sector has a robust and productive future.

The study is a comparative analysis of two fast reflection symmetry axis detection methods: an algorithm to refine the symmetry axis found with a chain of skeletal primitives and a boundary method based on the Fourier descriptor. We tested the algorithms with binary raster images of plant leaves (FLAVIA database). The symmetry axis detection quality and performance indicate that both methods can be used to solve applied problems. Neither method demonstrated any significant advantage in terms of accuracy or performance. It is advisable to integrate both methods for solving real-life problems.

The article presents a description of the family case of rare hereditary prion disease – Gerstmann–Sträussler–Scheinker syndrome with a verified p.P102L mutation in the PRNP gene. The clinical picture was represented by progressive cerebellar ataxia, pyramidal signs, bulbar syndrome, and neuropathy, which made it possible to establish a preliminary diagnosis of autosomal dominant spinocerebellar ataxia. Subsequently, the final diagnosis was verified using the massive parallel sequencing technology. The features of this observation are the variable age of onset within the family, with the unusually early age of the disease onset in the proband (age of 25 years), the absence of cognitive impairment, as well as the absence of pathological changes in the electroencephalography and brain MRI study. The possible modifying role of polymorphism in codon 129 of the PRNP gene (129Val) in the disease phenotype formation, as well as the clinical findings and diagnostic methods of this syndrome are discussed.

Introduction. Parkinson's disease (PD) is a neurodegenerative disorder, and the development of biomarkers is essential due to complicated PD diagnosis and progression assessment. Objective. To identify PD RNA markers by multiplex expression profiling of 760 genes associated with the main neuropathological processes. Materials and methods. We studied the expression of 760 genes associated with the main neuropathological processes using Nanostring nCounter Human Neuropathology Panel in 29 blood samples obtained from PD patients, including 13 samples from those in the early stage and 16 samples from those in the advanced stage, and in 16 control blood samples. Results. The comparison of gene expression in the patients with early PD and in the controls demonstrated differential expression of genes CDKN1A and CPT1B. The comparison of gene expression in the patients with advanced PD and in the controls showed LRP1 upregulation in the advanced PD group. We also revealed СPT1B upregulation in advanced disease, with a positive correlation between СPT1B expression and PD duration. Discussion. The variably expressed genes may be relevant as PD biomarkers for diagnosis and progression assessment.

Multiple system atrophy (MSA) is a neurodegenerative disease belonging to a group of synucleinopathies and characterized by significant autonomic failure, parkinsonian syndrome, and cerebellar signs. Diagnostic criteria used currently were updated in 2022. While the clinical method and neuroimaging are typically diagnostic in MSA, new modalities are currently emerging. Novel candidate biomarkers are being intensively and thoroughly studied. The review analyzes the clinical picture and diagnostic criteria of the disease, describes imaging methods for diagnosing synucleinopathies, as well as known laboratory markers of multiple system atrophy.

The publication analyzes the content of one of the first domestic predictions in the field of geopolitics – the information and analytical work «The Future War», prepared in 1928 by specialists of the IV (intelligence) Directorate of the Red Army Headquarters under the leadership of the Chief of Staff of the Red Army M. N. Tukhachevsky. The history of the creation of the work is presented, the accuracy of the forecasts proposed by theorists is analyzed, and the modern relevance of this study is revealed in the light of the current global geopolitical situation, when Russia, as in the 1920s, is opposed by a block of unfriendly states.

Мета статті полягає у теоретичному аналізі проблеми морального дистресу в науковій літературі, з’ясуванні основних аспектів вивчення відповідної проблематики та встановленні особливостей прояву морального дистресу шляхом вторинного аналізу результатів емпіричних досліджень науковців. Методи. У статті застосовано методи теоретичного вивчення наукової літератури (аналіз, синтез, узагальнення, систематизація підходів науковців) стосовно висвітлення проблеми переживання морального дистресу. Результати. Проблеми морального дистресу в науковій літературі висвітлюється здебільшого шляхом її вивчення в ході реалізації професійної діяльності медичних працівників. Моральний дистрес розглядають як моральні страждання, які виникають в особистості в ситуації наявності знань про те, яким чином потрібно діяти, але неможливості діяти відповідно, через встановлені інституційних обмежень. Виокремлюють види морального дистресу: первинний (описують власне як моральний дистрес) та реактивний (розглядається як «моральний залишок»). Емпіричними маркерами морального дистресу є: почуття гніву, розчарування та провини, неможливість втілення морального судження в дію, невпевненість у собі, відсутність наполегливості, конформізм, уявне безсилля, відсутність критичності і розуміння ситуації тощо. Фізичними наслідками тривалого переживання морального дистресу для особистості можуть бути: безсоння, нудоту, мігрені, кишково-шлункові розлади, плаксивість та значне фізичне виснаження. В якості необхідної та/або достатньої умови переживання морального дистресу, на думку науковців, можуть виступати: моральне судження/необхідність вибору, інституційне/правове обмеження, психологічний ефект/вплив, моральний конфлікт, загроза моральної цілісності та автентичності, внутрішні обмеження та моральний клімат установи. У єдності з теорією морального дистресу розглядають теорію моральної розплати, стрижнем якої є аналіз переживання моральної розплати медсестрою: легкість, ситуативна прив’язка, вирішення та рефлексія. Висновки. Здійснений теоретичний аналіз проблеми морального дистресу засвідчив складність та неоднозначність у визначені відповідного поняття, його показників та чинників. Теоретична розвідка означеної проблематики вказує на доцільність та важливість ґрунтованого вивчення морального дистресу з урахуванням вікового, статевого та професійного аспектів, а також актуальність та необхідність розробки програми психологічної підтримки осіб, які переживають моральний дистрес, комплексу заходів для збереження психічного здоров’я вразливих верств населення в умовах військових дій.

Multiple system atrophy (MSA) is a neurodegenerative disorder characterized by autonomous insufficiency and motor abnormalities, such as akinetic rigid syndrome and cerebellar ataxia. The diagnosis of this disorder is challenging, and quite frequently the patients are seen by other specialties or with other diagnoses. The paper presents three clinical observations of patients with various phenotypic MSA subtypes. In two of them, the diagnosis of MSA was clinically proven and in the third one, clinically probable. All patients were initially followed up with other diagnoses. The authors describe specifics of complaints and past history registration, neurological examination and typical signs of MSA at neuroimaging.

The article explores one of the modern trends in the semiotic analysis of the city and urban environment — the study of the cultural code of the city. In the contemporary aca­de­mic discourse, the importance of studying the cultural code of the city is growing not so much as a phenomenon but as a system of decoding and cognizing each specific city in its own con­text. This aspect is closely related to the analysis of the problem of enhancing urban identity and local patriotism, as well as identifying the unique cultural meanings of the city as part of exp­loring its image in the external environment. As the basis for the study of the cultural code of the city, it is proposed to consider the following factors encoding of urban environ­ment: a) nature and climate, b) texts, where the city is conceptualized and presented in litera­ry context, c) historical events associated with the city, d) spatial characteristics, e) symbolic relationship with famous individuals (“geniuses of place”). The process of coding is inf­luenced by other features of the city, which form economic, culinary, tourist, digital and other codes of the city, and their decoding can be carried out both on the everyday level and on the expert (academic) level. The author identifies the main ways of expressing, capturing and communicating the city’s cultural code in signs of different origin.

Aim. To consider and analyze early and late complications that occur during autologous soft tissue augmentation in dental practice, since knowledge of complications helps the doctor to choose the right approach and materials for the treatment of any disease.Materials and methods. The publications in the electronic databases PubMed , Google Scholar and other reliable resources, were studied during a systematic review of the literature. the author has selected articles whose content concerns the study of complications arising from autologous soft tissue augmentation in outpatient dental practice.Results. 71 articles we reviewed during the review. After analyzing the literature for inclusion criteria, the total number of publications has become 30.Conclusions. according to the studied literature, it can be assumed that the main complications arising from autologous soft tissue augmentation in dental practice include: bleeding, pain, swelling, increased sensitization, damage to nerve and/or vascular elements and flap necrosis.

Aim. Based on original and bibliographic data, to compile a review of the fauna of gall midges in Dagestan, Russia, including information about host plants, gall formation, life cycles and distribution.Materials and Methods. The basis for the work were materials collected in the flat and mountainous parts of Dagestan. Standard methods were used: inspection of the plants, search and mass collection of galls and damage to plants in which larvae develop; rearing imago; making permanent preparations of larvae and adults.Results. For the first time, an overview of the gall midges of Dagestan is offered. 67 species of gall midges of 41 genera were identified, of which 39 species are new to Dagestan, including 13 species new to the Caucasus: Asphondylia hornigi Wachtl, 1880, A. menthae Kieffer, 1902, A. salviaflorae Fedotova, 2003, Lasioptera eryngii (Vallot, 1829), Rosomyia spiraeae Fedotova, 1987, Dracunculomyia saissanica Fedotova, 1999, Dasineura plicatrix (Loew, 1850), D. sisymbrii (Schrank, 1803), D. trifolii (Löw, 1874), D. tamaricicarpa Fedotova, 1983, Asiodiplosis hodukini Marikovskij, 1965, A. petrosimoniae (Fedotova, 1994), Seriphidomyia butakovi Fedotova, 2000. Of these the last 4 are new to Russia. Phytophage gall midges (64 species of 36 genera) were found on plants belonging to 23 families, 46 genera and 56 species. Of the 36 genera of gall midges, 28 (77.8%) are plant‐specific to plant families, including 9 out of 28 (32.1%) monotypic. The fauna is based on the Western Palearctic and Turanian species.Conclusion. A preliminary review of gall midges in Dagestan in comparison with data on adjacent territories, indicates a very poor study of gall midges in general. Identification of the species diversity and trophic relationships of gall midges which develop on adventitious, invasive and economically important plants of the Caucasus is relevant both for protected natural areas and recreational areas.

The object of the study is digital assets and digital intellectual assets as objects of valuation. The subject of the research are the principles, factors, approaches and methods of assessing the value of digital assets, including digital intellectual assets, in order to involve them in civil turnover in modern realities. The relevance of the problem is caused, on the one hand, by the formation of new types of assets — digital, including intellectual — in the context of digitalization of the economy and public relations, on the other — by the uncertainties arising during their identification, as well as the need to substantiate the applicability of valuation principles, approaches and methods to determine the value of such assets for further involvement in civil turnover. The purpose of the study is to substantiate the principles, factors, approaches and methods applicable to the valuation of digital intellectual assets, their approbation on specific examples (domain names). Methods of statistical and comparative analysis, generalization, classification, and valuation were used. The essential characteristics of digital intellectual assets have been defined: intangible nature, creation with the help of digital technology; manifestation of value in the information system; the ability to civil (property) turnover as objects of intellectual rights. The applicability of valuation principles, income and comparative approaches to the valuation of digital intellectual assets is substantiated. The factors influencing the value of digital intellectual assets, as well as specific factors characteristic of one of the types of digital intellectual assets — domain names are identified. An example of using the analogs method to estimate the cost of a second-level domain name in the framework of a comparative approach is shown. It is concluded that digital intellectual assets satisfying all essential characteristics can be put on the balance sheet as intangible assets, and their market value is determined on the basis of income or comparative approaches using the principles of evaluation and identified factors.

FeO ⋅ Fe2O3 ⋅ nH2O, Fe2.95Gd0.05O4 and Fe2.9Gd0.1O4 powders were obtained by chemical precipitation from aqueous solutions. The phase composition and local environment of iron ions in gadolinium-doped iron oxide nanoparticles were studied by X-ray diffraction analysis and nuclear gamma resonance (NGR) spectroscopy. Interpretation of radiographs and NGR spectra of synthesised samples indicates the presence of a superposition of maghemite γ-Fe2O3 and iron hydroxide α-FeOOH in the samples. It was found that under the deposition of powders in the presence of gadolinium nitrate, an increase in the content of iron hydroxide α-FeOOH is observed, which disappears after annealing at 200 °C.

The article analyzes the transformation of the methodological toolkit for teaching humanities and sciences in the Russian Federation. The method of case study, being widely spread in modern higher education research, is used as an example to illustrate the attempts to implement the best practices of foreign educational technology into tertiary academic process in Russia. The authors provide some historical aspects of introducing case studies in modern teaching practice. The article features peculiarities of the Soviet approach to the structure of cases. Content analysis helps to identify similarities and differences in Soviet/post-Soviet approaches to case study construction and brings into focus the problem points which reveal misinterpretation and/or misuse of didactic materials designated as cases. The approach suggested in the article implies presenting the content of a case study as a collection of documents related to a certain topic. The case study "Istanbul in the life and work of the artist Martiros Saryan" demonstrates that a case can have invariable and variable parts to reflect the specificity of the didactic task within the discipline. Such approach is expected to support students' cognitive activity, develop creativity in searching additional sources and missing materials, improve efficiency of students' autonomous work on solving complex problem solution.

A rare clinical variant of angina manifestation as part of the coronary steal syndrome in a patient with prior bilateral coronary artery bypass grafting and subtotal brachiocephalic trunk stenosis is considered.

Наслідки російської агресії для України є відчутними в усіх галузях економіки, але їх неможливо повністю спрогнозувати через продовження воєнних дій. Мета статті – дослідження відновлення української економіки крізь призму аналізу головних аспектів повоєнної відбудови, ключових елементів трансформації сфери страхування й звернення до її потенціалу як до шляху подальшого відновлення економічного сектора. Дослідження побудоване на підставі використання загальнонаукових методів аналізу, синтезу, абстрагування, індукції, пояснення та узагальнення. Проаналізовано проблему економічних утрат України на тлі глобальних викликів воєнного та повоєнного середовищ. Досліджено також перспективи відновлення української економіки в повоєнні часи, виділено основні напрями цього процесу. Окрему увагу звернено на можливості співпраці з іноземними фінансовими партнерами-донорами, гармонізацію податкового та фінансового законодавства відповідно до вимог інтеграції в Європейський Союз. Зауважено також на важливості трансформацій у розвитку людського капіталу, соціальної та критичної інфраструктури. Окрему увагу присвячено проблемам галузі страхування та ймовірним шляхам подолання економічних негараздів у цій царині. Визначено, що падіння платоспроможності підприємств і фізичних осіб може стати на заваді подальшому розвиткові повоєнної економіки України (зокрема й страхування). Водночас, ця проблема залишається малодослідженою, оскільки сьогодні визначити абсолютно всі наслідки російсько-української війни неможливо.

Background. Sedentary and unhealthy lifestyle behaviors are modifiable health risks that often develop during adolescence. A comprehensive analysis of unhealthy behaviors in adolescents with and without chronic health conditions (CHC) could inform the development of more effective prevention approaches. The aim. This study aimed to measure associations between Problematic Internet Use (PIU), lifestyle habits and subjective health complaints among adolescents with and without CHC. In addition, health behaviors and prevalence of subjective health complaints between adolescents with and without CHC were compared. Methods. A total of 171 adolescents (87 without CHC and 84 with CHC) completed an online survey. The PIU was assessed by the Problematic and Risky Internet Use Screening Scale. The subjective health complaints assessed were somatic and psychological symptoms. Healthy lifestyle behaviors assessed were daily physical activities, time spent by screens, eating habits, and duration of sleep. Results. The results showed that 21.83% of adolescents with CHC and 36.78% without CHC scored at risk for problematic internet use. Adolescents without CHC reported significantly more frequent psychological health complaints than their peers with CHC. This study found that multiple health complaints and unhealthy eating habits were significantly associated with PIU in adolescents with CHC, while nervousness and eating fast food in adolescents without CHC. Girls without CHC reported significantly higher PRIUSS scores and prevalence of subjective health complaints than boys (p

Agenesis of the aortic and pulmonary valves is a very rare congenital malformation of the semilunar valves. The literature describes no more than thirty cases of such anomaly in combination with congenital heart disease. Most descriptions include aplasia of either the aortic or pulmonic valve. The combination of such defect in both valves has been described in a much smaller number of scientific papers.In this article, we present a clinical case of the treatment of a patient with agenesis of aortic valve and severely hypoplastic pulmonary valve. As a result circulatory arrest occurred immediately after birth, which required the implementation of cardiopulmonary resuscitation. The child was resuscitated and transferred to the intensive care unit for further examination and treatment.