Search

Your search keyword '"Eluri, Swathi"' showing total 530 results
Start Over Author "Eluri, Swathi"
530 results on '"Eluri, Swathi"'

169. Association Between Body Mass Index and Clinical and Endoscopic Features of Eosinophilic Esophagitis

Author

Wolf, W. Asher, primary, Piazza, Nicholas A., additional, Gebhart, Jessica H., additional, Rusin, Spencer, additional, Covey, Shannon, additional, Higgins, Leana L., additional, Beitia, RoseMary, additional, Speck, Olga, additional, Woodward, Kimberly, additional, Cotton, Cary C., additional, Runge, Thomas M., additional, Eluri, Swathi, additional, Woosley, John T., additional, Shaheen, Nicholas J., additional, and Dellon, Evan S., additional

Published
2016
Full Text
View/download PDF

171. Association between serrated epithelial changes and colorectal dysplasia in inflammatory bowel disease

Author

Parian, Alyssa, primary, Koh, Joyce, additional, Limketkai, Berkeley N., additional, Eluri, Swathi, additional, Rubin, David T., additional, Brant, Steven R., additional, Ha, Christina Y., additional, Bayless, Theodore M., additional, Giardiello, Francis, additional, Hart, John, additional, Montgomery, Elizabeth, additional, and Lazarev, Mark G., additional

Published
2016
Full Text
View/download PDF

184. Burden of Gastrointestinal, Liver, and Pancreatic Diseases in the United States

Author

Peery, Anne F., primary, Crockett, Seth D., additional, Barritt, Alfred S., additional, Dellon, Evan S., additional, Eluri, Swathi, additional, Gangarosa, Lisa M., additional, Jensen, Elizabeth T., additional, Lund, Jennifer L., additional, Pasricha, Sarina, additional, Runge, Thomas, additional, Schmidt, Monica, additional, Shaheen, Nicholas J., additional, and Sandler, Robert S., additional

Published
2015
Full Text
View/download PDF

185. Nearly a Third of High-Grade Dysplasia and Colorectal Cancer Is Undetected in Patients with Inflammatory Bowel Disease.

Author

Eluri, Swathi, Parian, Alyssa, Limketkai, Berkeley, Ha, Christina, Brant, Steven, Dudley-Brown, Sharon, Efron, Jonathan, Fang, Sandy, Gearhart, Susan, Marohn, Michael, Meltzer, Stephen, Bashar, Safar, Truta, Brindusa, Montgomery, Elizabeth, Lazarev, Mark, Parian, Alyssa M, Limketkai, Berkeley N, Ha, Christina Y, Brant, Steven R, and Efron, Jonathan E

Subjects
*COLON cancer diagnosis, *COLON cancer patients, *PUBLIC health, *MEDICAL quality control, *ULCERATIVE colitis, *PATIENTS, *MANAGEMENT, *ADENOCARCINOMA, *COLECTOMY, *COLON tumors, *COLONOSCOPY, *INFLAMMATORY bowel diseases, *RESEARCH funding, *DISEASE prevalence, *RETROSPECTIVE studies, *DISEASE complications, *DIAGNOSIS, RECTUM tumors
Abstract

Background: It is unclear whether intensive surveillance protocols have resulted in a decreased incidence of colorectal cancer (CRC) in inflammatory bowel disease (IBD).Aims: To determine the prevalence and characteristics of IBD associated high-grade dysplasia (HGD) or CRC that was undetected on prior colonoscopy.Methods: This is a single-center, retrospective study from 1994 to 2013. All participants had a confirmed IBD diagnosis and underwent a colectomy with either HGD or CRC found in the colectomy specimen.The undetected group had no HGD or CRC on prior colonoscopies. The detected group had HGD or CRC identified on previous biopsies.Results: Of 70 participants, with ulcerative colitis (UC) (n = 47), Crohn's disease (CD) (n = 21), and indeterminate colitis (n = 2), 29% (n = 20) had undetected HGD/CRC at colectomy (15 HGD and 5 CRC). In the undetected group, 75% had prior LGD, 15% had indefinite dysplasia, and 10% had no dysplasia (HGD was found in colonic strictures). Patients in the undetected group were more likely to have pancolitis (55 vs. 20%) and multifocal dysplasia (35 vs. 8%). The undetected group was less likely to have CRC at colectomy (25 vs. 62%). There was a trend toward right-sided HGD/CRC at colectomy (40 vs. 20%; p = 0.08). In addition, 84% of the lesions found in the rectum at colectomy were not seen on prior colonoscopy in the undetected group.Conclusions: The prevalence of previously undetected HGD/CRC in IBD found at colectomy was 29%. The high proportion of undetected rectal and right-sided HGD/CRC suggests that these areas may need greater attention during surveillance. [ABSTRACT FROM AUTHOR]

Published
2017
Full Text
View/download PDF

186. Higher Body Mass Index Is Associated With Decreased Treatment Response to Topical Steroids in Eosinophilic Esophagitis.

Author

Ketchem, Corey J., Ocampo, Adolfo A., Xue, Zeyun, Chang, Nicole C., Thakkar, Kisan P., Reddy, Sumana, Greenberg, Sydney B., Lee, Christopher J., Redd, Walker D., Eluri, Swathi, Reed, Craig C., and Dellon, Evan S.

Abstract

Understanding which eosinophilic esophagitis (EoE) patients will respond to treatment with topical corticosteroids (tCS) remains challenging, and it is unknown whether obesity impacts treatment response. This study aimed to determine whether treatment outcomes to tCS in EoE patients vary by body mass index (BMI). This retrospective cohort study of the University of North Carolina EoE Clinicopathologic database assessed subjects age 14 years or older with a new diagnosis of EoE. Their BMI was calculated and histologic, symptom, and endoscopic responses were recorded after tCS treatment. The treatment response of obese (BMI, ≥30 kg/m2) and nonobese EoE status was compared using bivariate and multivariate analyses. We identified 296 EoE patients treated with tCS. Baseline characteristics were similar, although obese EoE patients had more heartburn and hiatal hernias. Histologic response was higher for those who were nonobese compared with obese at fewer than 15 (61% vs 47%; P =.049) and 6 or fewer (54% vs 38%; P =.02) eosinophils per high-power field, respectively. In addition, nonobese patients had significantly greater endoscopic and symptomatic responses. On multivariate analysis, increasing BMI was associated independently with decreased histologic response after accounting for age, heartburn, dilation, and hiatal hernia whether BMI was assessed as a continuous variable (adjusted odds ratio [aOR], 0.93; 95% CI, 0.89–0.98), as nonobese vs obese (aOR, 0.38; 95% CI, 0.21–0.68), or in 4 categories (overweight vs normal [aOR, 0.46; 95% CI, 0.26–0.84] or obese vs normal [aOR, 0.26; 95% CI, 0.13–0.51]). As BMI increases in EoE patients, the odds of histologic, symptomatic, and endoscopic responses to tCS decreases, with obese patients having an approximately 40% decrease in odds of response. [Display omitted] [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

200. The Presence of Genetic Mutations at Key Loci Predicts Progression to Esophageal Adenocarcinoma in Barrett’s Esophagus

Author

Eluri, Swathi, primary, Brugge, William R, additional, Daglilar, Ebubekir S, additional, Jackson, Sara A, additional, Styn, Mindi A, additional, Callenberg, Keith M, additional, Welch, Derek C, additional, Barr, Todd M, additional, Duits, Lucas C, additional, Bergman, Jacques J, additional, and Shaheen, Nicholas J, additional

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results