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6,543 results on '"Elgendy A"'

151. Correction: Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations.

Author

Iliana K Kerzeli, Martin Lord, Milena Doroszko, Ramy Elgendy, Aikaterini Chourlia, Ivan Stepanek, Elinor Larsson, Luuk van Hooren, Sven Nelander, Per-Uno Malmstrom, Anca Dragomir, Ulrika Segersten, and Sara M Mangsbo

Subjects
Medicine, Science
Abstract

[This corrects the article DOI: 10.1371/journal.pone.0253178.].

Published
2024
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154. Radioprotective potential of whey protein against gamma irradiation-induced lingual damage

Author

Hanaa M. Hassan, Asmaa M. Abdeen, Ibrahim Y. Abdelrahman, Walied Abdo, Saher S. Mohammed, Ahmed Abdeen, Afaf Abdelkader, Rada Olga, Liana Fericean, Samah F. Ibrahim, Heba I. Ghamry, Farouk S. Elgendy, Safwa M. Sorour, Abeer A. Eldeeb, Osama Ahmed, Fatema Rashed, and Maha M. Bikheet

Subjects
ionizing radiation, whey protein, inflammation, mRNA expression, oxidative damage, tongue, Therapeutics. Pharmacology, RM1-950
Abstract

Introduction: Ionizing radiation (IR) is effectively used in the treatment of oral malignancies; however, it might also significantly harm the surrounding tissues. Whey protein isolate (WP) is a protein derived from milk that exhibits a wide range of bioactivities. Therefore, the present research aimed to delineate the mitigating impact of WP against gamma irradiation-induced lingual damage.Methods: Rats were randomized into 5 groups: Control (saline, orally, 14 days), WP (WP; 0.5 g/kg b. w., orally, 14 days), IR (saline, orally, 14 days, exposed to 6 and 3 Gy on days 4 and 6, respectively), WP+IR (WP was given orally for 14 days before and after IR exposure; exposed to 6 and 3 Gy on days 4 and 6, respectively), and IR+WP (WP, orally, started 24 h after 1st IR exposure till the end of the experiment) groups. Samples were collected at two-time intervals (on the 7th and 14th days).Results and Discussion: Oxidative stress was stimulated upon IR exposure in tongue, indicated by boosted malondialdehyde (MDA) level, along with a decrease in the total antioxidant capacity (TAC) level, superoxide dismutase (SOD), and catalase (CAT) activities. Additionally, IR exposure depicted an increase of serum IgE, inflammatory cytokines, including tumor necrosis factor-α (TNF-α), interleukin (IL)-6, along with overexpression mRNA levels of nuclear factor kappa-B transcription factor/p65 (NF-κB/p65), and down-regulation of nuclear factor erythroid 2–related factor 2 (NRF2) and heme oxygenase (HO-1) mRNA levels in tongue tissue. Moreover, IR triggered alterations in lingual histological architecture. The antioxidant and anti-inflammatory properties of WP mitigated oxidative damage, inflammation, and desquamation that were brought on following IR exposure. The protective administration of WP markedly decreases IR-induced lingual harm compared to the mitigation protocol. Our findings recommend WP supplements to the diets of cancer patients undergoing IR that might aid radioprotective effects.

Published
2023
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155. Identification of new 4-(6-oxopyridazin-1-yl)benzenesulfonamides as multi-target anti-inflammatory agents targeting carbonic anhydrase, COX-2 and 5-LOX enzymes: synthesis, biological evaluations and modelling insights

Author

Waleed A. Badawi, Mahmoud Rashed, Alessio Nocentini, Alessandro Bonardi, Mohammad M. Abd-Alhaseeb, Sara T. Al-Rashood, Giri Babu Veerakanellore, Taghreed A. Majrashi, Eslam B. Elkaeed, Bahaa Elgendy, Paola Gratteri, Claudiu T. Supuran, Wagdy M. Eldehna, and Mohamed Elagawany

Subjects
Analgesic, Synthesis, Pyridazinone, Sulphonates, Molecular modelling, Therapeutics. Pharmacology, RM1-950
Abstract

Multiple inhibitions of CA, COX-2 and 5-LOX enzymes has been recognised as a useful strategy for the development of anti-inflammatory drugs that can avoid the disadvantages of using NSAIDs alone. Here, we report new pyridazine-based sulphonamides (5a-c and 7a-f) as potential multi-target anti-inflammatory candidates. First, the furanone heterocycle in the dual CA/COX-2 inhibitor Polmacoxib was replaced with the pyridazinone one. Then, a hydrophobic tail was appended through benzylation of the 3-hydroxyl group of the pyridazinone scaffold to afford benzyloxy pyridazines 5a-c. Furthermore, the structures were adorned with the polar sulphonate functionality, in pyridazine sulphonates 7a-f, that are expected to be engaged in interactions with the hydrophilic half of the CA binding sites. All of the disclosed pyridazinones were tested for inhibitory activities against 4 hCA isoforms (I, II, IX, and XII), as well as against COX-1/2, and 5-LOX. Furthermore, in vivo anti-inflammatory and analgesic effects of pyridazinones 7a and 7b were examined.

Published
2023
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156. Syringeable atorvastatin loaded eugenol enriched PEGylated cubosomes in-situ gel for the intra-pocket treatment of periodontitis: statistical optimization and clinical assessment

Author

Heba Amin Elgendy, Amna M. A. Makky, Yara E. Elakkad, Radwa M. Ismail, and Nihal Farid Younes

Subjects
Intra-pocket delivery, periodontitis, atorvastatin, cubosomes, Box-Behnken design, and clinical assessment, Therapeutics. Pharmacology, RM1-950
Abstract

AbstractAtorvastatin calcium (ATV) is a well-known anti-hyperlipidemic drug currently being recognized for possessing an anti-inflammatory effect. Introducing it as a novel remedy for periodontitis treatment necessitates developing a syringeable modified delivery system capable of targeting inflammation within the periodontal pockets. Thus, a 33 Box-Behnken design was used to generate eugenol enriched PEGylated cubosomes. Based on the desirability function, the optimized formulation (OEEPC) was selected exhibiting a solubilization efficiency (SE%) of 97.71 ± 0.49%, particle size (PS) of 135.20 ± 1.11 nm, polydispersity index (PDI) of 0.09 ± 0.006, zeta potential (ZP) of −28.30 ± 1.84 mV and showing a sustained drug release over 12 h. It displayed a cubic structure under the transmission electron microscope, furthermore, it was stable upon storage for up to 30 days. Hence, it was loaded into an optimum syringeable in-situ gel (ISG) which displayed the desired periodontal gelation temperature (34 ± 0.70 °C) and an adequate gelation time (46 ± 2.82 sec), it also released approximately 75% of the drug within 72 h. Clinical evaluation of the ISG showed a promising percentage reduction of about 58.33% in probing depth, 90% in the bleeding index, 81.81% in the plaque index, and 70.21% in gingival levels of transforming growth factor–β1. This proved that the formulated syringeable intra-pocket delivery system of ATV is an efficient candidate for diminishing inflammation in periodontitis.

Published
2023
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157. Deep brain stimulation for chronic pain: a systematic review and meta-analysis

Author

Nour Shaheen, Ahmed Shaheen, Abdelrahman Elgendy, Yarema B. Bezchlibnyk, Theresa Zesiewicz, Brian Dalm, Jennifer Jain, Alexander L. Green, Tipu Z. Aziz, and Oliver Flouty

Subjects
chronic pain, pain, deep brain stimulation, DBS, neuromodulation, neurostimulation, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract

BackgroundDeep brain stimulation (DBS) has shown promise in effectively treating chronic pain. This study aimed to assess the efficacy of DBS in this context.MethodsWe conducted a systematic literature search using PubMed, Scopus, and Web of Science, following the PRISMA guidelines. A well-constructed search strategy was utilized. Our literature search identified two groups of subjects: one group underwent DBS specifically for chronic pain treatment (DBS-P), while the second group received DBS for other indications (DBS-O), such as Parkinson’s disease or dystonia, with pain perception investigated as a secondary outcome in this population. Meta-analysis was performed using R version 4.2.3 software. Heterogeneity was assessed using the tau^2 and I^2 indices, and Cochran’s Q-test was conducted.ResultsThe analysis included 966 patients in 43 original research studies with chronic pain who underwent DBS (340 for DBS-P and 625 for DBS-O). Subgroup analysis revealed that DBS-P exhibited a significant effect on chronic pain relief, with a standardized mean difference (SMD) of 1.65 and a 95% confidence interval (CI) of [1.31; 2.00]. Significant heterogeneity was observed among the studies, with an I^2 value of 85.8%. However, no significant difference was found between DBS-P and DBS-O subgroups. Subgroup analyses based on study design, age, pain diseases, and brain targets demonstrated varying levels of evidence for the effectiveness of DBS across different subgroups. Additionally, meta-regression analyses showed no significant relationship between age or pain duration and DBS effectiveness for chronic pain.ConclusionThese findings significantly contribute to the expanding body of knowledge regarding the utility of DBS in the management of chronic pain. The study underscores the importance of conducting further research to enhance treatment outcomes and elucidate patient-specific factors that are associated with treatment response.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?RecordID=428442, identifier CRD42023428442.

Published
2023
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162. Estrogen-Related Receptor Agonism Reverses Mitochondrial Dysfunction and Inflammation in the Aging Kidney

Author

Wang, Xiaoxin X., Myakala, Komuraiah, Libby, Andrew E., Krawczyk, Ewa, Panov, Julia, Jones, Bryce A., Bhasin, Kanchan, Shults, Nataliia, Qi, Yue, Krausz, Kristopher W., Zerfas, Patricia M., Takahashi, Shogo, Daneshpajouhnejad, Parnaz, Titievsky, Avi, Taranenko, Elizaveta, Billon, Cyrielle, Chatterjee, Arindam, Elgendy, Bahaa, Walker, John K., Albanese, Chris, Kopp, Jeffrey B., Rosenberg, Avi Z., Gonzalez, Frank J., Guha, Udayan, Brodsky, Leonid, Burris, Thomas P., and Levi, Moshe

Published
2023
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164. Management of Women With Acquired Cardiovascular Disease From Pre-Conception Through Pregnancy and Postpartum JACC Focus Seminar 3/5

Author

Park, Ki, Merz, C Noel Bairey, Bello, Natalie A, Davis, Melinda, Duvernoy, Claire, Elgendy, Islam Y, Ferdinand, Keith C, Hameed, Afshan, Itchhaporia, Dipti, Minissian, Margo B, Reynolds, Harmony, Mehta, Puja, Russo, Andrea M, Shah, Rashmee U, Volgman, Annabelle Santos, Wei, Janet, Wenger, Nanette K, Pepine, Carl J, Lindley, Kathryn J, and Group, American College of Cardiology Cardiovascular Disease in Women Committee and the Cardio-Obstetrics Work

Subjects
Reproductive Medicine, Biomedical and Clinical Sciences, Cardiovascular, Heart Disease, Reproductive health and childbirth, Good Health and Well Being, Cardiovascular Diseases, Female, Heart Disease Risk Factors, Humans, Patient Care Management, Peripartum Period, Practice Guidelines as Topic, Pregnancy, Pregnancy Complications, Cardiovascular, Risk Adjustment, cardio-obstetrics, hypertensive disorders of pregnancy, ischemic heart disease, pregnancy, arrhythmia, American College of Cardiology Cardiovascular Disease in Women Committee and the Cardio-Obstetrics Work Group, Cardiorespiratory Medicine and Haematology, Public Health and Health Services, Cardiovascular System & Hematology, Cardiovascular medicine and haematology
Abstract

Acquired cardiovascular conditions are a leading cause of maternal morbidity and mortality. A growing number of pregnant women have acquired and heritable cardiovascular conditions and cardiovascular risk factors. As the average age of childbearing women increases, the prevalence of acute coronary syndromes, cardiomyopathy, and other cardiovascular complications in pregnancy are also expected to increase. This document, the third of a 5-part series, aims to provide practical guidance on the management of such conditions encompassing pre-conception through acute management and considerations for delivery.

Published
2021

165. Pooled Analysis of PFO Occluder Device Trials in Patients With PFO and Migraine

Author

Mojadidi, Mohammad K, Kumar, Preetham, Mahmoud, Ahmed N, Elgendy, Islam Y, Shapiro, Hilary, West, Brian, Charles, Andrew C, Mattle, Heinrich P, Sorensen, Sherman, Meier, Bernhard, Silberstein, Stephen D, and Tobis, Jonathan M

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Neurosciences, Cardiovascular, Clinical Trials and Supportive Activities, Headaches, Migraines, Chronic Pain, Pain Research, Clinical Research, Foramen Ovale, Patent, Humans, Migraine Disorders, Randomized Controlled Trials as Topic, Septal Occluder Device, migraine headache with aura, patent foramen ovale, PFO occluder, PREMIUM trial, PRIMA trial, Cardiorespiratory Medicine and Haematology, Public Health and Health Services, Cardiovascular System & Hematology, Cardiovascular medicine and haematology
Abstract

BackgroundAlthough observational studies have shown percutaneous patent foramen ovale (PFO) closure to be a safe means of reducing the frequency and duration of migraine, randomized clinical trials have not met their primary efficacy endpoints.ObjectivesThe authors report the results of a pooled analysis of individual participant data from the 2 randomized trials using the Amplatzer PFO Occluder to assess the efficacy and safety of percutaneous device closure as a therapy for episodic migraine with or without aura.MethodsThe authors analyzed individual patient-level data from 2 randomized migraine trials (the PRIMA [Percutaneous Closure of Patent Foramen Ovale in Migraine With Aura] and PREMIUM [Prospective Randomized Investigation to Evaluate Incidence of Headache Reduction in Subjects with Migraine and PFO Using the Amplatzer PFO Occluder Compared to Medical Management] studies). Efficacy endpoints were mean reduction in monthly migraine days, responder rate (defined as ≥50% reduction in monthly migraine attacks), mean reduction in monthly migraine attacks, and percentage of patients who experienced complete cessation of migraine. The safety endpoint was major procedure- and device-related adverse events.ResultsAmong 337 subjects, 176 were randomized by blocks to device closure and 161 to medical treatment only. At 12-month follow-up, the analysis met 3 of the 4 efficacy endpoints: mean reduction of monthly migraine days (-3.1 days vs. -1.9 days; p = 0.02), mean reduction of monthly migraine attacks (-2.0 vs. -1.4; p = 0.01), and number of subjects who experienced complete cessation of migraine (14 [9%] vs. 1 [0.7%]; p

Published
2021

166. A collisional global sheath – Bulk model of argon plasma for semiconductor scale manufacturing

Author

A.T. Elgendy, N.M. Basfer, and Nuha Al-Harbi

Subjects
Global model, RF plasma, Plasma sheath, Semiconductor scale manufacturing, Engineering (General). Civil engineering (General), TA1-2040
Abstract

Plasma processes enhance the high-quality, semiconductor fabrication employed in large-scale industries. A crucial element in this process are the many gases that generate different reactive species at low temperatures. Capacitive plasma discharge radio frequency CCPs play a major role in semiconductor scale fabrication. The analysis of nonlinear dynamics in CCPs are complicated even under simple approaches. Therefore, we study self consistent collision fluid model, particle in cell simulation PIC, step approximation and finally the global model to find the accurate solution of merging plasma sheath -bulk region. For this purpose we study the self consistent collisional fluid model to find the accurate charge–voltage distribution V(Q) which controls the nonlinear dynamics of CCPs. The results against the PIC simulations and the more elaborate model step approximation is accomplished with higher accuracy. Consequently, the cubic polynomial formula V(Q) are applied in the global model. Accurate analytical global sheath-bulk calculations of the higher harmonic effect-exhibiting average power distributions, bulk potentials, and currents are obtained. This study provides an effective solution of collision regime for any arbitrary plasma reactor designs, including single-frequency and double frequency CCPs. Moreover, we used the argon gas as a good example in our study for a good ion etching. Finally, we can assist in achieving effective results that are consistent with experimental data and in large-scale applications in the semiconductor sector.

Published
2023
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168. Global burden of peripheral artery disease and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Author

Kim, Min Seo, Hwang, Jimin, Yon, Dong Keon, Lee, Seung Won, Jung, Se Yong, Park, Seoyeon, Johnson, Catherine Owens, Stark, Benjamin A, Razo, Christian, Abbasian, Mohammadreza, Abbastabar, Hedayat, Abhari, Amir Parsa, Aboyans, Victor, Adane, Denberu Eshetie Adane, Adebayo, Oladimeji M, Alahdab, Fares, Almustanyir, Sami, Aly, Hany, Ameyaw, Edward Kwabena, Anderson, Jason A, Andrei, Catalina Liliana, Aryan, Zahra, Aujayeb, Avinash, Bagherieh, Sara, Baltatu, Ovidiu Constantin, Banach, Maciej, Bayileyegn, Nebiyou Simegnew, Bearne, Lindsay M, Behnoush, Amir Hossein, Bensenor, Isabela M, Bhaskar, Sonu, Bhat, Ajay Nagesh, Bhat, Vivek, Bikbov, Boris, Bintoro, Bagas Suryo, Burkart, Katrin, Cámera, Luis Alberto, Catapano, Alberico L, Chandrasekar, Eeshwar K, Charan, Jaykaran, Chattu, Vijay Kumar, Chi, Gerald, Chukwu, Isaac Sunday, Chung, Sheng-Chia, Cirillo, Massimo, Coberly, Kaleb, Costa, Vera Marisa, Dadras, Omid, Dai, Xiaochen, Do, Thanh Chi, Doshi, Rajkumar, Ekholuenetale, Michael, Elgendy, Islam Y, Elhadi, Muhammed, Fagbamigbe, Adeniyi Francis, Feizkhah, Alireza, Fekadu, Ginenus, Gill, Paramjit Singh, Goldust, Mohamad, Golechha, Mahaveer, Guan, Shi-Yang, Gupta, Vivek Kumar, Hadei, Mostafa, Hadi, Najah R, Hammoud, Ahmad, Hankey, Graeme J, Harlianto, Netanja I, Hasaballah, Ahmed I, Hassan, Shoaib, Hassen, Mohammed Bheser, Heidari, Golnaz, Hostiuc, Mihaela, Ilesanmi, Olayinka Stephen, Iwagami, Masao, Jokar, Mohammad, Jonas, Jost B, Joshua, Charity Ehimwenma, Jozwiak, Jacek Jerzy, Kazemian, Sina, Keykhaei, Mohammad, Khalaji, Amirmohammad, Khan, Moien AB, Khateri, Sorour, Kibret, Biruk Getahun, Korzh, Oleksii, Koulmane Laxminarayana, Sindhura Lakshmi, Krishan, Kewal, Kumar, Akshay, Kumar, Manoj, Kuttikkattu, Ambily, Laksono, Tri, Larijani, Bagher, Le, Thao Thi Thu, Lim, Stephen S, Liu, Xuefeng, Lorkowski, Stefan, Magdy Abd El Razek, Hassan, Malhotra, Kashish, Manla, Yosef, Maugeri, Andrea, Mentis, Alexios-Fotios A, Mestrovic, Tomislav, Micheletti Gomide Nogueira de Sá, Ana Carolina, Mirica, Andreea, Mirrakhimov, Erkin M, Misganaw, Awoke, Mishra, Manish, Mohammad, Yousef, Mokdad, Ali H, Moni, Mohammad Ali, Montasir, Ahmed Al, Moradi, Yousef, Moraga, Paula, Morovatdar, Negar, Mousavi-Aghdas, Seyed Ali, Murray, Christopher J L, Naghavi, Mohsen, Nair, Tapas Sadasivan, Nassereldine, Hasan, Natto, Zuhair S, Nguyen, Dang H, Nguyen, Hien Quang, Nguyen, Van Thanh, Noubiap, Jean Jacques, Oancea, Bogdan, Oliveira, Gláucia Maria Moraes, Owolabi, Mayowa O, Padron-Monedero, Alicia, Perico, Norberto, Petcu, Ionela-Roxana, Radfar, Amir, Rafferty, Quinn, Rahman, Mosiur, Rahman, Muhammad Aziz, Ram, Pradhum, Rashedi, Sina, Rashid, Ahmed Mustafa, Rawaf, Salman, Remuzzi, Giuseppe, Renzaho, Andre M N, Rezaee, Malihe, Roever, Leonardo, Saad, Aly M A, Saadatagah, Seyedmohammad, Sadeghi, Masoumeh, Sahebkar, Amirhossein, Saleh, Mohamed A, Samy, Abdallah M, Santric-Milicevic, Milena M, Sepanlou, Sadaf G, Seylani, Allen, Sharfaei, Sadaf, Shorofi, Seyed Afshin, Singh, Jasvinder A, Singh, Paramdeep, Spartalis, Michael, Sundström, Johan, Tan, Ker-Kan, Teramoto, Masayuki, Tharwat, Samar, Tyrovolas, Stefanos, Valadan Tahbaz, Sahel, Van den Eynde, Jef, Vart, Priya, Wang, Cong, Wang, Fang, Westerman, Ronny, Xia, Juan, Xu, Suowen, Yada, Dereje Y, Yamagishi, Kazumasa, Yonemoto, Naohiro, Zahir, Mazyar, Zangiabadian, Moein, Zarrintan, Armin, Zastrozhin, Mikhail Sergeevich, Zastrozhina, Anasthasia, Zoladl, Mohammad, Hay, Simon I, Shin, Jae Il, and Roth, Gregory A

Published
2023
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175. Clinical and radiographic assessment of autogenous dentin nanoparticles in treatment of stage iii periodontitis: a split-mouth clinical study

Author

Enas Ahmed Elgendy, Ahmed Mohamed Elgendy, and Ola Mohammad ElBorady

Subjects
Bone transplantation, Tuberculin, Autografts, Heterografts, Periodontitis, Nanoparticles, Medicine
Abstract

Objective: To compare autogenous dentin nanoparticles with allograft bone grafts in the treatment of stage III periodontitis. Method: The randomised study was conducted at the Department of Oral Medicine and Periodontology, Faculty of Oral and Dental Medicine, Kafrelsheikh University Hospital, Egypt, from January 2021 to January 2022, and comprised adult patients of either gender with stage III periodontitis. Each patient’s bilateral intrabony defect was randomly treated with an allograft on one side and a graft made of dentin nanoparticles on the test side. Each patient’s removed tooth was ground into these nanoparticles. Both groups had their probing pocket depth and clinical attachment loss evaluated at baseline and six months after surgery. Additionally, digital periapical films were collected in both groups at baseline and six months after therapy to assess vertical bone loss. Data was analysed using SPSS 20. Results: Of the 20 patients, 8(40%) were males and 12(60%) were females with overall mean age 31.00±4.06 years (range: 18-50 years). Of the 40 sites, 20(50%) each were in test and control groups. Compared to baseline values, both groups showed significant improvement in probing pocket depth, clinical attachment loss and vertical bone loss postintervention (p0.05). Conclusion: Autogenous dentin nanoparticles were found to be an effective and promising biomaterial for bone regeneration in intrabony defects. Clinical Trial: NCT05258006 link: https://clinicaltrials.gov/ct2/show/NCT05258006, Registration date of the Trial 10/2/2022. Keywords: Bone transplantation, Tuberculin, Autografts, Heterografts, Periodontitis, Nanoparticles, Dentin.

Published
2023
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176. Effect of corticosteroid and immune-suppressive drugs on oral manifestations in hospitalized COVID-19 patients

Author

Ahmed Mohamed Al Elgendy, Enas Ahmed Elgendy, Marwa Sabry, Mohamed Kamal Salama, and Tamer Aboshady

Subjects
Tocilizumab, Dentists, Methylprednisolone, COVID-19, Medicine
Abstract

Objective: To explore if the oral lesions in coronavirus disease-2019 patients are caused by the drugs used in the treatment or by the virus itself. Method: The cross-sectional study was conducted from September 2020 to September 2021 at the Kafrelsheikh University Hospital, Egypt, and comprised coronavirus disease-2019 patients of either gender aged 20-60 years having severe pneumonia and breathing difficulties who had no comorbidities. Based on the level of interleukin-6 and procalcitonin, the patients were classified into high group I receiving tocilizumab and methylprednisolone, medium group II receiving methylprednisolone alone, and low group III receiving antiviral drugs. The oral manifestations were recorded at the time of admission before treatment and at 2 weeks after the respective treatment. Data was analysed using SPSS 20. Results: Of the 90 patients, 30(33.3%) were in group I; 16(%) males and 14(%) females with mean age 44.82±6.10 years. Group II had 27(%) patients; 14(%) males and 13(%) females with mean age 43.74±4.87 years. Group III had 33(%) patients; 9(%) males and 14(%) females with mean age 42.66±2.51 years (p>0.05). There was no significant difference among the groups at baseline and after 2 weeks of treatment regarding oral manifestations. Intragroup comparison demonstrated a significant difference in the two values in all the three groups (p

Published
2023
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177. The effect of interleukin-6 and procalcitonin level on the development of oral manifestation in hospitalized COVID-19 patients

Author

Enas Ahmed Elgendy, Ahmed Mohammad Ali Elgendy, Marwa Sabry, Mohamed Kamal Salama, and Tamer Aboshady

Subjects
Interleukin, Procalcitonin, Ageusia, COVID-19, Gingivitis, Candidiasis, Medicine
Abstract

Objective: To evaluate the effect of interleukin-6 and procalcitonin levels in plasma on the development of oral manifestation in patients of coronavirus disease-2019. Methods: The case-control study was conducted from January to September 2021 at Kafrelsheikh University Hospital, Egypt, and comprised severe coronavirus disease. One hundred patients of either gender aged 30-60 years were included. The patients were divided into two equal groups, with group I having patients with oral manifestations, and group II had those without any oral symptoms. Plasma samples from both the groups were used to determine serum interleukin-6 and procalcitonin levels using electrochemiluminescence immunoassay. Data was analysed using SPSS 20. Result: Of the 100 patients, 50(50%) were in each of the two groups. Group I had 29(58%) males and 21(42%) females with overall mean age 44.83±6.12 years. Group II had 26(52%) males and 24(48%) females with overall mean age of 43.68±4.62 years. Interleukin 6 was significantly high in group I than in group II (p0.05). Conclusion: Interleukin-6 level could play an important role in the development of oral manifestation in coronavirus disease-2019 patients. Keyword: Interleukin, Procalcitonin, Ageusia, COVID-19, Gingivitis, Candidiasis, Mucous membrane, Immunoassay.

Published
2023
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181. Tailoring FXR Modulators for Intestinal Specificity: Recent Progress and Insights

Author

Amanda Morrison and Bahaa Elgendy

Subjects
farnesoid X receptor (FXR), intestinal selectivity, bile acid synthesis, metabolic diseases, drug design, Organic chemistry, QD241-441
Abstract

While FXR has shown promise in regulating bile acid synthesis and maintaining glucose and lipid homeostasis, undesired side effects have been observed in clinical trials. To address this issue, the development of intestinally restricted FXR modulators has gained attention as a new avenue for drug design with the potential for safer systematic effects. Our review examines all currently known intestinally restricted FXR ligands and provides insights into the steps taken to enhance intestinal selectivity.

Published
2024
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183. Effectiveness of Group Physical Exercise in Treating Major Depressive Disorder: An Analysis of Secondary Data from an Aborted Randomized Trial

Author

Hossam Elgendy, Reham Shalaby, Belinda Agyapong, Deanna Lesage, Lacey Paulsen, Amy Delday, Sherianna Duiker, Shireen Surood, Yifeng Wei, Nnamdi Nkire, and Vincent Israel Opoku Agyapong

Subjects
depression, exercise, physical activity, mental health, psychiatric patients, Psychology, BF1-990
Abstract

Background: Depression is highly prevalent and a significant cause of mortality and morbidity across the globe. Although antidepressants and/or psychotherapy are often used to treat depression, some recent studies indicate that exercise may play an important role in lowering depression symptoms among patients meeting the clinical criteria of a depressive episode. Objectives: This study aimed to evaluate the mental health and wellbeing of adult participants diagnosed with major depressive disorder (MDD) after fourteen weeks of receiving a supervised physical exercise program. Methods: In a pre-post design, the assessments were performed at baseline, seven weeks and fourteen weeks following the exercise intervention program using facilitated self-reported psychometric scales. The Beck Depression Inventory (BDI-2) and Clinical Outcomes in Routine Evaluation—Outcome Measure (CORE-OM) were used to assess depression. The short form of the International Physical Activity Questionnaire (IPAQ) was used for the self-reporting of participants’ physical activity. Results: At the beginning of the study, the baseline total mean scores and standard deviations for the BDI-2, CORE-OM, and IPAQ in both genders did not differ significantly (p-value > 0.05). Patients showed significant improvement in all assessment scales after completing fourteen weeks of the physical exercise program. Based on the BDI-2, the baseline score dropped from 31.25 (indicating moderate to severe depression) to 14.25 (indicating mild to minimal depression), with a p-value of p-value < 0.005 indicating effective clinical improvement in depression symptoms. The IPAQ total MET-minutes/week mean score increased from 1713.22 to 4367.62, indicating an improvement in the participants’ weekly P.E. intake; however, the change was not statistically significant (p = 0.07). Conclusions: Exercise treatment is linked with considerable therapeutic improvement in patients with MDD, particularly when exercise is sustained over time. The BDI-2 and CORE-OM total scores significantly decreased after the fourteen-week P.E. programme, indicating a change from moderate and severe depression to minimal and mild depression. Our findings offer insightful information to primary care doctors and psychiatrists, indicating that prescribing exercise to depressed patients may be a helpful adjunctive therapy.

Published
2024
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185. Exploring the cost-effectiveness of high versus low perioperative fraction of inspired oxygen in the prevention of surgical site infections among abdominal surgery patients in three low- and middle-income countries

Author

Mwayi Kachapila, Mark Monahan, Adesoji O. Ademuyiwa, Yakubu Momohsani Adinoyi, Bruce M. Biccard, Christina George, Dhruva N. Ghosh, James Glasbey, Dion G. Morton, Osaheni Osayomwanbo, Rupert Pearse, Tracy E. Roberts, Atul Suroy, Saidu Yusuf Yakubu, Raymond Oppong, Aneel Bhangu, Maria Lorena Aguilera, Philip Alexander, Sara W. Al-Saqqa, Giuliano Borda-Luque, Ainhoa Costas-Chavarri, Thomas M. Drake, Faustin Ntirenganya, J. Edward Fitzgerald, Stuart J. Fergusson, J.C. Allen Ingabire, Lawani Ismaïl, Hosni Khairy Salem, Anyomih Theophilus Teddy Kojo, Marie Carmela Lapitan, Richard Lilford, Andre L. Mihaljevic, Dion Morton, Alphonse Zeta Mutabazi, Dmitri Nepogodiev, Adewale O. Adisa, Riinu Ots, Francesco Pata, Thomas Pinkney, Tomas Poškus, Ahmad Uzair Qureshi, Antonio Ramos-De la Medina, Sarah Rayne, Catherine A. Shaw, Sebastian Shu, Richard Spence, Neil Smart, Stephen Tabiri, Ewen M. Harrison, Azmina Verjee, Emmy Runigamugabo, Chetan Khatri, Midhun Mohan, Zahra Jaffry, Afnan Altamini, Andrew Kirby, Kjetil Søreide, Gustavo Recinos, Jen Cornick, Maria Marta Modolo, Dushyant Iyer, Sebastian King, Tom Arthur, Sayeda Nazmum Nahar, Ade Waterman, Michael Walsh, Arnav Agarwal, Augusto Zani, Mohammed Firdouse, Tyler Rouse, Qinyang Liu, Juan Camilo Correa, Peep Talving, Mengistu Worku, Alexis Arnaud, Vassilis Kalles, Basant Kumar, Sunil Kumar, Radhian Amandito, Roy Quek, Luca Ansaloni, Ahmed Altibi, Donatas Venskutonis, Justas Zilinskas, Tomas Poskus, John Whitaker, Vanessa Msosa, Yong Yong Tew, Alexia Farrugia, Elaine Borg, Zineb Bentounsi, Tanzeela Gala, Ibrahim Al-Slaibi, Haya Tahboub, Osaid H. Alser, Diego Romani, Sebestian Shu, Piotr Major, Aurel Mironescu, Matei Bratu, Amar Kourdouli, Aliyu Ndajiwo, Abdulaziz Altwijri, Mohammed Ubaid Alsaggaf, Ahmad Gudal, Al Faifi Jubran, Sam Seisay, Bettina Lieske, Irene Ortega, Jenifa Jeyakumar, Kithsiri J. Senanayake, Omar Abdulbagi, Yucel Cengiz, Dmitri Raptis, Yuksel Altinel, Chia Kong, Ella Teasdale, Gareth Irwin, Michael Stoddart, Rakan Kabariti, Sukrit Suresh, Katherine Gash, Ragavan Narayanan, Mayaba Maimbo, Besmir Grizhja, Shpetim Ymeri, Gezim Galiqi, Roberto Klappenbach, Diego Antezana, Alvaro Enrique Mendoza Beleño, Cecilia Costa, Belen Sanchez, Susan Aviles, Claudio Gabriel Fermani, Rubén Balmaceda, Santiago Villalobos, Juan Manuel Carmona, Daniel Hamill, Peter Deutschmann, Simone Sandler, Daniel Cox, Ram Nataraja, Claire Sharpin, Damir Ljuhar, Demi Gray, Morgan Haines, Dush Iyer, Nithya Niranjan, Scott D'Amours, Morvarid Ashtari, Helena Franco, Ashrarur Rahman Mitul, Sabbir Karim, Nowrin F. Aman, Mahnuma Mahfuz Estee, Umme Salma, Joyeta Razzaque, Tasnia Hamid Kanta, Sayeeda Aktar Tori, Shadid Alamin, Swapnil Roy, Shadid Al Amin, Rezaul Karim, Muhtarima Haque, Amreen Faruq, Farhana Iftekhar, Margaret O'Shea, Greg Padmore, Ramesh Jonnalagadda, Andrey Litvin, Aliaksandr Filatau, Dzmitry Paulouski, Maryna Shubianok, Tatsiana Shachykava, Dzianis Khokha, Vladimir Khokha, Fernande Djivoh, Francis Dossou, Djifid Morel Seto, Dansou Gaspard Gbessi, Bruno Noukpozounkou, Yacoubou Imorou Souaibou, Kpèmahouton René Keke, Fred Hodonou, Ernest Yemalin Stephane Ahounou, Thierry Alihonou, Max Dénakpo, Germain Ahlonsou, Alemayehu Ginbo Bedada, Carlos Nsengiyumva, Sandrine Kwizera, Venerand Barendegere, Philip Choi, Simon Stock, Luai Jamal, Georges Azzie, Sameer Kushwaha, Tzu-Ling Chen, Chingwan Yip, Irene Montes, Felipe Zapata, Sebastian Sierra, Maria Isabel Villegas Lanau, Maria Clara Mendoza Arango, Ivan Mendoza Restrepo, Ruben Santiago Restrepo Giraldo, Edgar Domini, Robert Karlo, Jakov Mihanovic, Mohamed Youssef, Hossam Elfeki, Waleed Thabet, Aly Sanad, Gehad Tawfik, Ahmed Zaki, Noran Abdel-Hameed, Mohamed Mostafa, Muhammad Fathi Waleed Omar, Ahmed Ghanem, Emad Abdallah, Adel Denewar, Eman Emara, Eman Rashad, Ahmad Sakr, Rehab Elashry, Sameh Emile, Toqa Khafagy, Sara Elhamouly, Arwa Elfarargy, Amna Mamdouh Mohamed, Ghada Saied Nagy, Abeer Esam, Eman Elwy, Aya Hammad, Salwa Khallaf, Eman Ibrahim, Ahmed Saidbadr, Ahmed Moustafa, Amany Eldosouky Mohammed, Mohammed Elgheriany, Eman Abdelmageed, Eman Abd Al Raouf, Esraa Samir Elbanby, Maha Elmasry, Mahitab Morsy Farahat, Eman Yahya Mansor, Eman Magdy Hegazy, Esraa Gamal, Heba Gamal, Hend Kandil, Doaa Maher Abdelrouf, Mohamed Moaty, Dina Gamal, Nada El-Sagheer, Mohamed Salah, Salma Magdy, Asmaa Salah, Ahmed Essam, Ahmed Ali, Mahmoud Badawy, Sara Ahmed, Mazed Mohamed, Abdelrahman Assal, Mohamed Sleem, Mai Ebidy, Aly Abd Elrazek, Diaaaldin Zahran, Nourhan Adam, Mohamed Nazir, Adel B. Hassanein, Ahmed Ismail, Amira Elsawy, Rana Mamdouh, Mohamed Mabrouk, Lopna Ahmed Mohamed Ahmed, Mohamed Hassab Alnaby, Eman Magdy, Manar Abd-Elmawla, Marwan Fahim, Bassant Mowafy, Moustafa Ibrahim Mahmoud, Meran Allam, Muhammad Alkelani, Noran Halim El Gendy, Mariam Saad Aboul-Naga, Reham Alaa El-Din, Alyaa Halim Elgendy, Mohamed Ismail, Mahmoud Shalaby, Aya Adel Elsharkawy, Mahmoud Elsayed Moghazy, Khaled Hesham Elbisomy, Hend Adel Gawad Shakshouk, Mohamed Fouad Hamed, Mai Mohamed Ebidy, Mostafa Abdelkader, Mohamed Karkeet, Hayam Ahmed, Israa Adel, Mohammad Elsayed Omar, Mohamed Ibrahim, Omar Ghoneim, Omar Hesham, Shimaa Gamal, Karim Hilal, Omar Arafa, Sawsan Adel Awad, Menatalla Salem, Fawzia Abdellatif Elsherif, Nourhan Elsabbagh, Moustafa R. Aboelsoud, Ahmed Hossam Eldin Fouad Rida, Amr Hossameldin, Ethar Hany, Yomna Hosny Asar, Nourhan Anwar, Mohamed Gadelkarim, Samar Abdelhady, Eman Mohamed Morshedy, Reham Saad, Nourhan Soliman, Mahmoud Salama, Eslam Ezzat, Arwa Mohamed, Arwa Ibrahim, Alaa Fergany, Sara Mohammed, Aya Reda, Yomna Allam, Hanan Adel Saad, Afnan Abdelfatah, Aya Mohamed Fathy, Ahmed El-Sehily, Esraa Abdalmageed Kasem, Ahmed Tarek Abdelbaset Hassan, Ahmed Rabeih Mohammed, Abdalla Gamal Saad, Yasmin Elfouly, Nesma Elfouly, Arij Ibrahim, Amr Hassaan, Mohammed Mustafa Mohammed, Ghada Elhoseny, Mohamed Magdy, Esraa Abd Elkhalek, Yehia Zakaria, Tarek Ezzat, Ali Abo El Dahab, Mohamed Kelany, Sara Arafa, Osama Mokhtar Mohamed Hassan, Nermin Mohamed Badwi, Ahmad Saber Sleem, Hussien Ahmed, Kholoud Abdelbadeai, Mohamed Abozed Abdullah, Muhammad Amsyar Auni Lokman, Suraya Bahar, Anan Rady Abdelazeam, Abdelrahman Adelshone, Muhammad Bin Hasnan, Athirah Zulkifli, Siti Nur Alia Kamarulzamil, Abdelaziz Elhendawy, Aliang Latif, Ahmad Bin Adnan, Shahadatul Shaharuddin, Aminah Hanum Haji Abdul Majid, Mahmoud Amreia, Dina Al-Marakby, Mahmoud Salma, Mohamad Jeffrey Bin Ismail, Elissa Rifhan Mohd Basir, Citra Dewi, Mohd Ali, Aya Yehia Ata, Maha Nasr, Asmaa Rezq, Ahmed Sheta, Sherif Tariq, Abd Elkhalek Sallam, Abdelrhman K.Z. Darwish, Sohaila Elmihy, Shady Elhadry, Ahmed Farag, Haidar Hajeh, Abdelaziz Abdelaal, Amro Aglan, Ahmed Zohair, Mahitab Essam, Omar Moussa, Esraa El-Gizawy, Mostafa Samy, Safia Ali, Esraa Elhalawany, Ahmed Ata, Mohamed El Halawany, Mohamed Nashat, Samar Soliman, Alaa Elazab, Mostada Samy, Mohamed A. Abdelaziz, Khaled Ibrahim, Ahmed mohamed Ibrahim, Ammar Gado, Usama Hantour, Esraa Alm Eldeen, Mohamed Reda loaloa, Arwa Abouzaid, Mostafa Ahmed Bahaa Eldin, Eman Hashad, Fathy Sroor, Doaa Gamil, Eman Mahmoud Abdulhakeem, Mahmoud Zakaria, Fawzy Mohamed, Marwan Abubakr, Elsayed Ali, Hesham Magdy, Menna Tallah Ramadan, Mohamed Abdelaty Mohamed, Salma Mansour, Hager Abdul Aziz Amin, Ahmed Rabie Mohamed, Mahmoud Saami, Nada Ahmed Reda Elsayed, Adham Tarek, Sabry Mohy Eldeen Mahmoud, Islam Magdy El Sayed, Amira Reda, Martina Yusuf Shawky, Mohammed Mousa Salem, Shahinaz Alaa El-Din, Noha Abdullah Soliman, Muhammed Talaat, Shahinaz Alaael-Dein, Ahmed Abd Elmoen Elhusseiny, Noha Abdullah, Mohammed Elshaar, Aya AbdelFatah Ibraheem, Hager Abdulaziz, Mohammed Kamal Ismail, Mona Hamdy Madkor, Mohamed Abdelaty, Sara Mahmoud Abdel-Kader, Osama Mohamed Salah, Mahmoud Eldafrawy, Ahmed Zaki Eldeeb, Mostafa Mahmoud Eid, Attia Attia, Khalid Salah El-Dien, Ayman Shwky, Mohamed Adel Badenjki, Abdelrahman Soliman, Samaa Mahmoud Al Attar, Farrag Sayed, Fahd Abdel Sabour, Mohammed G. Azizeldine, Muhammad Shawqi, Abdullah Hashim, Ahmed Aamer, Ahmed Mahmoud Abdelraouf, Mahmoud Abdelshakour, Amal Ibrahim, Basma Mahmoud, Mohamed Ali Mahmoud, Mostafa Qenawy, Ahmed M. Rashed, Ahmed Dahy, Marwa Sayed, Ahmed W. Shamsedine, Bakeer Mohamed, Ahmad Hasan, Mahmoud M. Saad, Khalil Abdul Bassit, Nadia Khalid Abd El-Latif, Nada Elzahed, Ahmed El Kashash, Nada Mohamed Bekhet, Sarah Hafez, Ahmed Gad, Mahmoud Elkhadragy Maher, Ahmed Abd Elsameea, Mohamed Hafez, Ahmad Sabe, Ataa Ahmed, Ahmed Shahine, Khaled Dawood, Shireen Gaafar, Reem Husseiny, Omnia Aboelmagd, Ahmed Soliman, Nourhan Mesbah, Hossam Emadeldin, Amgad Al Meligy, Amira Hassan Bekhet, Doaa Hasan, Khaled Alhady, Ahmad Khaled Sabe, Mahmoud A. Elnajjar, Majed Aboelella, Ward Hamsho, Ihab Hassan, Hala Saad, Galaleldin Abdelazim, Hend Mahmoud, Noha Wael, Ahmedali M. Kandil, Ahmed Magdy, Shimaa Said Elkholy, Badr Eldin Adel, Kareem Dabbour, Saged Elsherbiney, Omar Mattar, Abdulshafi Khaled Abdrabou, Mohammed Yahia Mohamed Aly, Abdelrahman Geuoshy, Ahmedglal Elnagar, Saraibrahim Ahmed, Ibrahem Abdelmotaleb, Amr Ahmed Saleh, Manar Saeed, Shady Mahmoud, Badreldin Adel Tawfik, Samar Adel Ismail, Esraay Zakaria, Mariam O. Gad, Mohamed Salah Elhelbawy, Monica Bassem, Noha Maraie, Nourhan Medhat Elhadary, Nourhan Semeda, Shaza Rabie Mohamed, Hesham Mohammed Bakry, A.A. Essam, Dina Tarek, Khlood Ashour, Alaa Elhadad, Abdulrahman Abdel-Aty, Ibrahim Rakha, Sara Mamdouh Matter, Rasha Abdelhamed, Omar Abdelkader, Ayat Hassaan, Yasmin Soliman, Amna Mohamed, Sara Ghanem, Sara Amr Mohamed Farouk, Eman Mohamed Ibrahim, Esraa El-Taher, Merna Mostafa, Mohamed Fawzy Mahrous Badr, Rofida Elsemelawy, Aya El-Sawy, Ahmad Bakr, Ahmad Abdel Razaq Al Rafati, Sten Saar, Arvo Reinsoo, Nebyou Seyoum, Tewodros Worku, Agazi Fitsum, Matti Tolonen, Ari Leppäniemi, Ville Sallinen, Benoît Parmentier, Matthieu Peycelon, Sabine Irtan, Sabrina Dardenne, Elsa Robert, Betty Maillot, Etienne Courboin, Alexis Pierre Arnaud, Juliette Hascoet, Olivier Abbo, Amir Ait Kaci, Thomas Prudhomme, Quentin Ballouhey, Céline Grosos, Laurent Fourcade, Tolg Cecilia, Colombani Jean-Francois, Francois-Coridon Helene, Xavier Delforge, Elodie Haraux, Bertrand Dousset, Roberto Schiavone, Sebastien Gaujoux, Jean-Baptiste Marret, Aurore Haffreingue, Julien Rod, Mariette Renaux-Petel, Jean-François Lecompte, Jean Bréaud, Pauline Gastaldi, Chouikh Taieb, Raquillet Claire, Echaieb Anis, Nasir Bustangi, Manuel Lopezv, Aurelien Scalabre, Maria Giovanna Grella, Aurora Mariani, Guillaume Podevin, Françoise Schmitt, Erik Hervieux, Aline Broch, Cecile Muller, Dickson Bandoh, Francis Abantanga, Martin Kyereh, Hamza Asumah, Eric Kofi Appiah, Paul Wondoh, Adam Gyedu, Charles Dally, Kwabena Agbedinu, Michael Amoah, Abiboye Yifieyeh, Frank Owusu, Mabel Amoako-Boateng, Makafui Dayie, Richmond Hagan, Sam Debrah, Micheal Ohene-Yeboah, Joe-Nat Clegg-Lampety, Victor Etwire, Jonathan Dakubo, Samuel Essoun, William Bonney, Hope Glover-Addy, Samuel Osei-Nketiah, Joachim Amoako, Niiarmah Adu-Aryee, William Appeadu-Mensah, Antoinette Bediako-Bowan, Florence Dedey, Mattew Ekow, Emmanuel Akatibo, Musah Yakubu, Hope Edem Kofi Kordorwu, Kwasi Asare-Bediako, Enoch Tackie, Kenneth Aaniana, Emmanuel Acquah, Richard Opoku-Agyeman, Anthony Avoka, Kwasi Kusi, Kwame Maison, Frank Enoch Gyamfi, Gandau Naa Barnabas, Saiba Abdul-Latif, Philip Taah Amoako, Anthony Davor, Victor Dassah, Enoch Dagoe, Prince Kwakyeafriyie, Elliot Akoto, Eric Ackom, Ekow Mensah, Ebenezer Takyi Atkins, Christian Lari Coompson, Nikolaos Ivros, Christoforos Ferousis, Vasileios Kalles, Christos Agalianos, Ioannis Kyriazanos, Christos Barkolias, Angelos Tselos, Georgios Tzikos, Evangelos Voulgaris, Dimitrios Lytras, Athanasia Bamicha, Kyriakos Psarianos, Anastasios Stefanopoulos, Ioannis Patoulias, Dimitrios Sfougaris, Ioannis Valioulis, Dimitrios Balalis, Dimitrios Korkolis, Dimitrios K. Manatakis, Georgios Kyrou, Georgios Karabelias, Iason-Antonios Papaskarlatos, Kolonia Konstantina, Nikolaos Zampitis, Stylianos Germanos, Aspasia Papailia, Theodosios Theodosopoulos, Georgios Gkiokas, Magdalini Mitroudi, Christina Panteli, Thomas Feidantsis, Konstantinos Farmakis, Dimitrios Kyziridis, Orestis Ioannidis, Styliani Parpoudi, Georgios Gemenetzis, Stavros Parasyris, Christos Anthoulakis, Nikolaos Nikoloudis, Michail Margaritis, Maria-Lorena Aguilera-Arevalo, Otto Coyoy-Gaitan, Javier Rosales, Luis Tale, Rafael Soley, Emmanuel Barrios, Servio Tulio Torres Rodriguez, Carlos Paz Galvez, Danilo Herrera Cruz, Guillermo Sanchez Rosenberg, Alejandro Matheu, David Monterroso Cohen, Marie Paul, Angeline Charles, Justin Chak Yiu Lam, Man Hon Andrew Yeung, Chi Ying Jacquelyn Fok, Ka Hin Gabriel Li, Anthony Chuk-Him Lai, Yuk Hong Eric Cheung, Hong Yee Wong, Ka Wai Leung, Tien Seng Bryan Lee, Wai Him Lam, Weihei Dao, Stephanie Hiu-wai Kwok, Tsz-Yan Katie Chan, Yung Kok Ng, T.W.C. Mak, Chi Chung Foo, James Yang, Ankur Bhatnagar, Vijaid Upadhyaya, Uday Muddebihal, Wasim Dar, K.C. Janardha, Neerav Aruldas, Fidelis Jacklyn Adella, Anthonius Santoso Rulie, Ferdy Iskandar, Jonny Setiawan, Cicilia Viany Evajelista, Hani Natalie, Arlindawati Suyadi, Rudy Gunawan, Herlin Karismaningtyas, Lusi Padma Sulistianingsih Mata, Ferry Fitriya Ayu Andika, Afifatun Hasanah, T. Ariani Widiastini, Nurlaila Ayu Purwaningsih, Annisa Dewi Fitriana Mukin, Dina Faizatur Rahmah, Hazmi Dwinanda Nurqistan, Hasbi Maulana Arsyad, Novia Adhitama, Wifanto Saditya Jeo, Nathania Sutandi, Audrey Clarissa, Phebe Anggita Gultom, Matthew Billy, Andreass Haloho, Nadya Johanna, Felix Lee, Radin Mohd Nurrahman Radin Dorani, Martha Glynn, Mohammad Alherz, Wennweoi Goh, Haaris A. Shiwani, Lorraine Sproule, Kevin C. Conlon, Miklosh Bala, Asaf Kedar, Luca Turati, Federica Bianco, Francesca Steccanella, Gaetano Gallo, Mario Trompetto, Giuseppe Clerico, Matteo Papandrea, Giuseppe Sammarco, Rosario Sacco, Angelo Benevento, Luisa Giavarini, Mariano Cesare Giglio, Luigi Bucci, Gianluca Pagano, Viviana Sollazzo, Roberto Peltrini, Gaetano Luglio, Arianna Birindelli, Salomone Di Saverio, Gregorio Tugnoli, Miguel Angel Paludi, Pietro Mingrone, Domenica Pata, Francesco Selvaggi, Lucio Selvaggi, Gianluca Pellino, Natale Di Martino, Gianluca Curletti, Paolo Aonzo, Raffaele Galleano, Stefano Berti, Elisa Francone, Silvia Boni, Laura Lorenzon, Annalisa lo Conte, Genoveffa Balducci, Gianmaria Confalonieri, Giovanni Pesenti, Laura Gavagna, Giorgio Vasquez, Simone Targa, Savino Occhionorelli, Dario Andreotti, Giacomo Pata, Andrea Armellini, Deborah Chiesa, Fabrizio Aquilino, Nicola Chetta, Arcangelo Picciariello, Mohamed Abdelkhalek, Andrea Belli, Silvia De Franciscis, Annamaria Bigaran, Alessandro Favero, Stefano M.M. Basso, Paola Salusso, Martina Perino, Sylvie Mochet, Diego Sasia, Francesco Riente, Marco Migliore, David Merlini, Silvia Basilicò, Carlo Corbellini, Veronica Lazzari, Yuri Macchitella, Luigi Bonavina, Daniele Angelieri, Diego Coletta, Federica Falaschi, Marco Catani, Claudia Reali, Mariastella Malavenda, Celeste Del Basso, Sergio Ribaldi, Massimo Coletti, Andrea Natili, Norma Depalma, Immacolata Iannone, Angelo Antoniozzi, Davide Rossi, Daniele Gui, Gerardo Perrotta, Matteo Ripa, Francesco Ruben Giardino, Maurizio Foco, Erika Vicario, Federico Coccolini, Gabriela Elisa Nita, Nicoletta Leone, Andrea Bondurri, Anna Maffioli, Andrea Simioni, Davide De Boni, Sandro Pasquali, Elena Goldin, Elena Vendramin, Eleonora Ciccioli, Umberto Tedeschi, Luca Bortolasi, Paola Violi, Tommaso Campagnaro, Simone Conci, Giovanni Lazzari, Calogero Iacono, Alfredo Gulielmi, Serena Manfreda, Anna Rinaldi, Maria Novella Ringressi, Beatrice Brunoni, Giuseppe Salamone, Mirko Mangiapane, Paolino De Marco, Antonella La Brocca, Roberta Tutino, Vania Silvestri, Leo Licari, Tommaso Fontana, Nicolò Falco, Gianfranco Cocorullo, Mostafa Shalaby, Pierpaolo Sileri, Claudio Arcudi, Isam Bsisu, Khaled Aljboor, Lana Abusalem, Aseel Alnusairat, Ahmad Qaissieh, Emad Al-Dakka, Ali Ababneh, Oday Halhouli, Taha Yusufali, Hussein Mohammed, Justus Lando, Robert Parker, Wairimu Ndegwa, Mantas Jokubauskas, Jolanta Gribauskaite, Justas Kuliavas, Audrius Dulskas, Narimantas E. Samalavicius, Kristijonas Jasaitis, Audrius Parseliunas, Viktorija Nevieraite, Margarita Montrimaite, Evelina Slapelyte, Edvinas Dainius, Romualdas Riauka, Zilvinas Dambrauskas, Andrejus Subocius, Linas Venclauskas, Antanas Gulbinas, Saulius Bradulskis, Simona Kasputyte, Deimante Mikuckyte, Mindaugas Kiudelis, Tomas Jankus, Steponas Petrikenas, Matas Pažuskis, Zigmantas Urniežius, Mantas Vilčinskas, Vincas Jonas Banaitis, Vytautas Gaižauskas, Edvard Grisin, Povilas Mazrimas, Rokas Rackauskas, Mantas Drungilas, Karolis Lagunavicius, Vytautas Lipnickas, Dovilè Majauskyté, Valdemaras Jotautas, Tomas Abaliksta, Laimonas Uščinas, Gintaras Simutis, Adomas Ladukas, Donatas Danys, Erikas Laugzemys, Saulius Mikalauskas, Elena Zdanyte Sruogiene, Petras Višinskas, Reda Žilinskienė, Deividas Dragatas, Andrius Burmistrovas, Zygimantas Tverskis, Arturas Vaicius, Ruta Mazelyte, Antanas Zadoroznas, Nerijus Kaselis, Greta Žiubrytė, Finaritra Casimir Fleur Prudence Rahantasoa, Luc Hervé Samison, Fanjandrainy Rasoaherinomenjanahary, Todisoa Emmanuella Christina Tolotra, Cornelius Mukuzunga, Chimwemwe Kwatiwani, Nelson Msiska, Feng Yih Chai, Siti Mohd Desa Asilah, Khuzaimah Zahid Syibrah, Pui Xin Chin, Afizah Salleh, Nur Zulaika Riswan, April Camilla Roslani, Hoong-Yin Chong, Nora Abdul Aziz, Keat-Seong Poh, Chu-Ann Chai, Sandip Kumar, Mustafa Mohammed Taher, Nik Ritza Kosai, Dayang Nita Abdul Aziz, Reynu Rajan, Rokayah Julaihi, Durvesh Lacthman Jethwani, Muhammad Taqiyuddin Yahaya, Nik Azim Nik Abdullah, Susan Wndy Mathew, Kuet Jun Chung, Milaksh Kumar Nirumal, R. Goh Ern Tze, Syed Abdul Wahhab Eusoffee Wan Ali, Yiing Yee Gan, Jesse Ron Swire Ting, Samuel S.Y. Sii, Kean Leong Koay, Yi Koon Tan, Alvin Ee Zhiun Cheah, Chui Yee Wong, Tuan Nur'Azmah Tuan Mat, Crystal Yern Nee Chow, Prisca A.L. Har, Yishan Der, Fitjerald Henry, Xinwei Low, Ya Theng Neo, Hian Ee Heng, Shu Ning Kong, Cheewei Gan, Yi Ting Mok, Yee Wen Tan, Kandasami Palayan, Mahadevan Deva Tata, Yih Jeng Cheong, Kuhaendran Gunaseelan, Wan Nurul 'Ain Wan Mohd Nasir, Pigeneswaren Yoganathan, Eu Xian Lee, Jian Er Saw, Li Jing Yeang, Pei Ying Koh, Shyang Yee Lim, Shuang Yi Teo, Nicole Grech, Daniela Magri, Kristina Cassar, Christine Mizzi, Malcolm Falzon, Nihaal Shaikh, Ruth Scicluna, Stefan Zammit, Sean Mizzi, Svetlana Doris Brincat, Thelma Tembo, Vu Thanh Hien Le, Tara Grima, Keith Sammut, Kurt Carabott, Ciskje Zarb, Andre Navarro, Thea Dimech, Georgette Marie Camilleri, Isaac Bertuello, Jeffrey Dalli, Karl Bonavia, Samantha Corro-Diaz, Marisol Manriquez-Reyes, Amina Abdelhamid, Abdelmalek Hrora, Sarah Benammi, Houda Bachri, Meryem Abbouch, Khaoula Boukhal, Redouane Mammar Bennai, Abdelkader Belkouchi, Mohamed Sobhi Jabal, Chaymae Benyaiche, Maarten Vermaas, Lucia Duinhouwer, Javier Pastora, Greta Wood, Maria Soledad Merlo, Akinlabi Ajao, Omobolaji Ayandipo, Taiwo Lawal, Abdussemiu Abdurrazzaaq, Muslimat Alada, Abdulrasheed Nasir, James Adeniran, Olufemi Habeeb, Ademola Popoola, Ademola Adeyeye, Ademola Adebanjo, Opeoluwa Adesanya, Adewale Adeniyi, Henry Mendel, Bashir Bello, Umar Muktar, Adedapo Osinowo, Thomas Olagboyega Olajide, Oyindamola Oshati, George Ihediwa, Babajide Adenekan, Victor Nwinee, Felix Alakaloko, Adesoji Ademuyiwa, Olumide Elebute, Abdulrazzaq Lawal, Chris Bode, Mojolaoluwa Olugbemi, Alaba Adesina, Olubukola Faturoti, Oluwatomi Odutola, Oluwaseyi Adebola, Clement Onuoha, Ogechukwu Taiwo, Omolara Williams, Fatai Balogun, Olalekan Ajai, Mobolaji Oludara, Iloba Njokanma, Roland Osuoji, Stephen Kache, Jonathan Ajah, Jerry Makama, Ahmed Adamu, Suleiman Baba, Mohammad Aliyu, Shamsudeen Aliyu, Yahaya Ukwenya, Halima Aliyu, Tunde Sholadoye, Muhammad Daniyan, Oluseyi Ogunsua, Lofty-John Anyanwu, Abdurrahaman Sheshe, Aminu Mohammad, Samson Olori, Philip Mshelbwala, Babatunde Odeyemi, Garba Samson, Oyediran Kehinde Timothy, Sani Ali Samuel, Anthony Ajiboye, Isaac Amole, Olajide Abiola, Akin Olaolorun, Torhild Veen, Arezo Kanani, Kristian Styles, Ragnar Herikstad, Johannes Wiik Larsen, Jon Arne Søreide, Elisabeth Jensen, Mads Gran, Eirik Kjus Aahlin, Tina Gaarder, Peter Wiel Monrad-Hansen, Pål Aksel Næss, Giedrius Lauzikas, Joachim Wiborg, Silje Holte, Knut Magne Augestad, Gurpreet Singh Banipal, Michela Monteleone, Thomas Tetens Moe, Johannes Kurt Schultz, Taher Al-Taher, Ayah Hamdan, Ayman Salman, Rana Saadeh, Aseel Musleh, Dana Jaradat, Soha Abushamleh, Sakhaa Hanoun, Amjad Abu Qumbos, Aseel Hamarshi, Ayman, Taher, Israa Qawasmi, Khalid Qurie, Marwa Altarayra, Mohammad Ghannam, Alaa Shaheen, Azher Herebat, Aram Abdelhaq, Ahmad Shalabi, Maram Abu-Toyour, Fatema Asi, Ala Shamasneh, Anwar Atiyeh, Mousa Mustafa, Rula Zaa'treh, Majd Dabboor, Enas Alaloul, Heba Baraka, Jehad Meqbil, Alaa Al-Buhaisi, Mohamedraed Elshami, Samah Afana, Sahar Jaber, Said Alyacoubi, Yousef Abuowda, Tasneem Idress, Eman Abuqwaider, Sara Al-Saqqa, Alaa Bowabsak, Alaa El Jamassi, Doaa Hasanain, Hadeel Al-Farram, Maram Salah, Aya Firwana, Marwa Hamdan, Israa Awad, Ahmad Ashour, Fayez Elian Al Barrawi, Ahmed Al-Khatib, Maha Al-Faqawi, Mohamed Fares, Amjad Elmashala, Mohammad Adawi, Ihdaa Adawi, Reem Khreishi, Rose Khreishi, Ahed Ghaben, Najwa Nadeem, Muhammad Saqlain, Jibran Abbasy, Abdul Rehman Alvi, Noman Shahzad, Kamran Faisal Bhopal, Zainab Iftikhar, Muhammad Talha Butt, Syed Asaat Ul Razi, Asdaq Ahmed, Ali Khan Niazi, Ibrahim Raza, Fatima Baluch, Ahmed Raza, Ahmad Bani-Sadar, Muhammad Adil, Awais Raza, Mahnoor Javaid, Muhammad Waqar, Maryam Ali Khan, Mohammad Mohsin Arshad, Mohammadasim Amjad, Gustavo Miguel Machain Vega, Jorge Torres Cardozo, Marcelo O´Higgins Roche, Gustavo Rodolfo Pertersen Servin, Helmut Alfredo Segovia Lohse, Larissa Ines Páez Lopez, Ramón Augusto Melo Cardozo, Fernando Espinoza, Angel David Pérez Rojas, Diana Sanchez, Camila Sanchez Samaniego, Shalon Guevara Torres, Alexander Canta Calua, Cesar Razuri, Nadia Ortiz, Xianelle Rodriguez, Nahilia Carrasco, Fridiz Saravia, Hector Shibao Miyasato, María Valcarcel-Saldaña, Ysabel Esthefany Alejos Bermúdez, Juan Carpio, Walter Ruiz Panez, Pedro Angel Toribio Orbegozo, Carolina Guzmán Dueñas, Kevin Turpo Espinoza, Ana Maria Sandoval Barrantes, Jorge Armando Chungui Bravo, Lorena Fuentes-Rivera, Carmen Fernández, Bárbara Málaga, Joselyn Ye, Ricardo Velasquez, Jannin Salcedo, Ana Lucia Contreras-Vergara, Angelica Genoveva Vergara Mejia, Maria Soledad Gonzales Montejo, Marilia Del Carmen Escalante Salas, Willy Alcca Ticona, Marvin Vargas, George Christian Manrique Sila, Robinson Mas, Arazzelly del Pilar Paucar, Armando José Román Velásquez, Alina Robledo-Rabanal, Ludwing Alexander Zeta Solis, Kenny Turpo Espinoza, José Luis Hamasaki Hamaguchi, Erick Samuel Florez Farfan, Linda Alvi Madrid Barrientos, Juan Jaime Herrera Matta, John Jemuel V. Mora, Menold Archee P. Redota, Manuel Francisco Roxas, Maria Jesusa B. Maño, Marie Dione Parreno-Sacdalan, Christel Leanne Almanon, Maciej Walędziak, Rafał Roszkowski, Michał Janik, Anna Lasek, Dorota Radkowiak, Mateusz Rubinkiewicz, Cristina Fernandes, Jose Costa-Maia, Renato Melo, Liviu Muntean, Aurel Sandu Mironescu, Lucian Corneliu Vida, Mariuca Popa, Hogea Mircea, Mihaela Vartic, Bogdan Diaconescu, Matei Razvan Bratu, Ionut Negoi, Mircea Beuran, Cezar Ciubotaru, Norbert Uzabumwana, Dieudonne Duhoranenayo, Elio Jovine, Nicola Zanini, Giovanni Landolfo, Murad Aljiffry, Faisal Idris, Mohammed Saleh A. Alghamdi, Ashraf Maghrabi, Abdulmalik Altaf, Aroub Alkaaki, Ahmad Khoja, Abrar Nawawi, Sondos Turkustani, Eyad Khalifah, Adel Albiety, Sarah Sahel, Reham Alshareef, Mohammed Najjar, Ahmed Alzahrani, Ahmed Alghamdi, Wedyan Alhazmi, Ghiath Al Saied, Mohammed Alamoudi, Muhammed Masood Riaz, Mazen Hassanain, Basmah Alhassan, Abdullah Altamimi, Reem Alyahya, Norah Al Subaie, Fatema Al Bastawis, Afnan Altamimi, Thamer Nouh, Roaa Khan, Milan Radojkovic, Ljiljana Jeremic, Milica Nestorovic, Jia Hao Law, Keith Say Kwang Tan, Ryan Choon Kiat Tan, Joel Kin Tan, Lau Wen Liang Joel, Xue Wei Chan, Faith Qi Hui Leong, Choon Seng Chong, Sharon Koh, Kai Yin Lee, Kuok Chung Lee, Kent Pluke, Britta Dedekind, Puyearashid Nashidengo, Mark Ian Hampton, Johanna Joosten, Sanju Sobnach, Liana Roodt, Anthony Sander, James Pape, Niveshni Maistry, Phumudzo Ndwambi, Kamau Kinandu, Myint Tun, Frederick Du Toit, Quinn Ellison, D.C. Grobler, Sule Burger, Lawrence Bongani Khulu, Rachel Moore, Vicky Jennings, Astrid Leusink, Nazmie Kariem, Juan Gouws, Kathryn Chu, Heather Bougard, Fazlin Noor, Angela Dell, Stephanie Van Straten, Arvin Khamajeet, Serge Kapenda Tshisola, Kalangu Kabongo, Victor Kong, Yoshan Moodley, Frank Anderson, Thandinkosi Madiba, Flip du Plooy, Leila Hartford, Gareth Chilton, Parveen Karjiker, Matlou Ernest Mabitsela, Sibongile Ruth Ndlovu, Maria Badicel, Robert Jaich, Jaime Ruiz-Tovar, Luis Garcia-Florez, Jorge L. Otero-Díez, Virginia Ramos Pérez, Nuria Aguado Suárez, Javier Minguez García, Sara Corral Moreno, Maria Vicenta Collado, Virginia Jiménez Carneros, Javier García Septiem, Mariana Gonzalez, Antonio Picardo, Enrique Esteban, Esther Ferrero, Eloy Espin-Basany, Ruth Blanco-Colino, Valeria Andriola, Lorena Solar García, Elisa Contreras, Carmen García Bernardo, Janet Pagnozzi, Sandra Sanz, Alberto Miyar de León, Asnel Dorismé, Joseluis Rodicio, Aida Suarez, Jessica Stuva, Tamara Diaz Vico, Laura Fernandez-Vega, Carla Soldevila-Verdeguer, Fatima Sena-Ruiz, Natalia Pujol-Cano, Paula Diaz-Jover, José Maria Garcia-Perez, Juan Jose Segura-Sampedro, Cristina Pineño-Flores, David Ambrona-Zafra, Andrea Craus-Miguel, Patricia Jimenez-Morillas, Angela Mazzella, A.B. Jayathilake, S.P.B. Thalgaspitiya, L.S. Wijayarathna, P.M.S.N. Wimalge, Hakeem Ayomi Sanni, Ogheneochuko Okenabirhie, Anmar Homeida, Abobaker Younis, Omer Abdelbagi Omer, Mustafa Abdulaziz, Ali Mussad, Ali Adam, Ida Björklund, Sandra Ahlqvist, Anders Thorell, Fredrik Wogensen, Arestis Sokratous, Michaela Breistrand, Hildur Thorarinsdottir, Johanna Sigurdadottir, Maziar Nikberg, Abbas Chabok, Maria Hjertberg, Peter Elbe, Deborah Saraste, Wiktor Rutkowski, Louise Forlin, Karoliina Niska, Malin Sund, Dennis Oswald, Georgios Peros, Rafael Bluelle, Katharina Reinisch, Daniel Frey, Adrian Palma, Dimitri Aristotle Raptis, Lucius Zumbühl, Markus Zuber, Roger Schmid, Gabriela Werder, Antonio Nocito, Alexandra Gerosa, Silke Mahanty, Lukas Werner Widmer, Julia Müller, Alissa Gübeli, Grzegorz Zuk, Osman Bilgin Gulcicek, Talar Vartanoglu, Emin Kose, Servet Rustu Karahan, Mehmet Can Aydin, Nuri Alper Sahbaz, Ilkay Halicioglu, Halil Alis, Ipek Sapci, Can Adıyaman, Ahmet Murat Pektaş, Turgut Bora Cengiz, Ilkan Tansoker, Vedatcan Işler, Muazzez Cevik, Deniz Mutlu, Volkan Ozben, Berk Baris Ozmen, Sefa Bayram, Sinem Yolcu, Berna Buse Kobal, Ömer Faruk Toto, Haluk Cem Çakaloğlu, Kagan Karabulut, Vahit Mutlu, Bahar Busra Ozkan, Saban Celik, Anil Semiz, Selim Bodur, Enisburak Gül, Busra Murutoglu, Reyyan Yildirim, Bahadir Emre Baki, Ekin Arslan, Mehmet Ulusahin, Ali Guner, Nathan Walker, Nikhita Shrimanker, Simon Cole, Ryan Breslin, Ravi Srinivasan, Mohamed Elshaer, Kristina Hunter, Ahmed Al-Bahrani, Ignatius Liew, Nora Grace Mairs, Alistair Rocke, Lachlan Dick, Mobeen Qureshi, Debkumar Chowdhury, Naomi Wright, Clare Skerritt, Dorothy Kufeji, Adrienne Ho, Tharindra Dissanayake, Athula Tennakoon, Wadah Ali, Shujing Jane Lim, Charlene Tan, Stephen O'Neill, Catrin Jones, Stephen Knight, Dima Nassif, Abhishek Sharma, Oliver Warren, Rebecca White, Aia Mehdi, Nathan Post, Eliana Kalakouti, Enkhbat Dashnyam, Frederick Stourton, Ioannis Mykoniatis, Chelise Currow, Francisca Wong, Ashish Gupta, Veeranna Shatkar, Joshua Luck, Suraj Kadiwar, Alexander Smedley, Rebecca Wakefield, Philip Herrod, James Blackwell, Jonathan Lund, Fraser Cohen, Ashwath Bandi, Stefano Giuliani, Giles Bond-Smith, Theodore Pezas, Neda Farhangmehr, Tomas Urbonas, Miklos Perenyei, Philip Ireland, Natalie Blencowe, Kirk Bowling, David Bunting, Lydia Longstaff, Kenneth Keogh, Hyunjin Jeon, Muhammad Rafaih Iqbal, Shivun Khosla, Anna Jeffery, James Perera, Ahmad Aboelkassem Ibrahem, Tariq Alhammali, Yahya Salama, Shaun Oram, Thomas Kidd, Fraser Cullen, Christopher Owen, Michael Wilson, Seehui Chiu, Hannah Sarafilovic, Jennifer Ploski, Elizabeth Evans, Athar Abbas, Sylvia Kamya, Norzawani Ishak, Carly Bisset, Cedar Andress, Ye Ru Chin, Priya Patel, David Evans, Aidan Haslegrave, Adam Boggon, Kirsten Laurie, Katie Connor, Thomas Mann, Anahita Mansuri, Rachel Davies, Ewen Griffiths, Aized Raza Shahbaz, Calvin Eng, Farhat Din, Ariadne L'Heveder, Esther H.G. Park, Ramanish Ravishankar, Kirsten McIntosh, Jih Dar Yau, Luke Chan, Susan McGarvie, Lingshan Tang, Hui Lim, Suhhuey Yap, Jay Park, Zhan Herr Ng, Shahrukh Mirza, Yun Lin Ang, Luke Walls, Chloe Roy, Simon Paterson-Brown, Julian Camilleri-Brennan, Kenneth Mclean, Michelle S. D'Souza, Savva Pronin, David Ewart Henshall, Eunice Zuling Ter, Dina Fouad, Ashish Minocha, William English, Catrin Morgan, Dominic Townsend, Laura Maciejec, Shareef Mahdi, Onyinye Akpenyi, Elisabeth Hall, Hanaan Caydiid, Zakaria Rob, Tom Abbott, Hew D. Torrance, Robin Johnston, Mohammed Akil Gani, Gianpiero Gravante, Shivanchan Rajmohan, Kiran Majid, Shiva Dindyal, Christopher Smith, Madanmohan Palliyil, Sanjay Patel, Luke Nicholson, Neil Harvey, Katie Baillie, Sam Shillito, Suzanne Kershaw, Rebecca Bamford, Peter Orton, Elke Reunis, Robert Tyler, Wai Cheong Soon, Guled M. Jama, Dharminder Dhillon, Khyati Patel, Shayanthan Nanthakumaran, Rachel Heard, Kar Yan Chen, Behrad Barmayehvar, Uttaran Datta, Sivesh K. Kamarajah, Sharad Karandikar, Sobhana Iftekhar Tani, Eimear Monaghan, Philippa Donnelly, Michael Walker, Jehangirshaw Parakh, Sarah Blacker, Anil Kaul, Arjun Paramasivan, Sameh Farag, Ashrafun Nessa, Salwa Awadallah, Jieqi Lim, James Chean Khun Ng, Ravi P. Kiran, Alice Murray, Eric Etchill, Mohini Dasari, Juan Puyana, Nadeem Haddad, Martin Zielinski, Asad Choudhry, Celeste Caliman, Mieshia Beamon, Therese Duane, Mamta Swaroop, Jonathan Myers, Rebecca Deal, Erik Schadde, Mark Hemmila, Lena Napolitano, Kathleen To, Alex Makupe, Joseph Musowoya, Niels Van Der Naald, Dayson Kumwenda, Alex Reece-Smith, Kars Otten, Anna Verbeek, Marloes Prins, Alibeth Andres Baquero Suarez, Ruben Balmaceda, Chelsea Deane, Emilio Dijan, Mahmoud Elfiky, Laura Koskenvuo, Aurore Thollot, Bernard Limoges, Carmen Capito, Challine Alexandre, Henri Kotobi, Julien Leroux, Kalitha Pinnagoda, Nicolas Henric, Olivier Azzis, Olivier Rosello, Poddevin Francois, Sara Etienne, Philippe Buisson, Sophian Hmila, Joe-Nat Clegg-Lamptey, Osman Imoro, Owusu Emmanuel Abem, Dimitrios Papageorgiou, Vasiliki Soulou, Sabrina Asturias, Lenin Peña, Donal B. O’Connor, Alberto Realis Luc, Alfio Alessandro Russo, Andrea Ruzzenente, Antonio Taddei, Camilla Cona, Corrado Bottini, Giovanni Pascale, Giuseppe Rotunno, Leonardo Solaini, Marco Maria Pascale, Margherita Notarnicola, Mario Corbellino, Michele Sacco, Paolo Ubiali, Roberto Cautiero, Tommaso Bocchetti, Elena Muzio, Vania Guglielmo, Eugenio Morandi, Patrizio Mao, Emilia De Luca, Farah Mahmoud Ali, Justas Žilinskas, Kestutis Strupas, Paulius Kondrotas, Robertas Baltrunas, Juozas Kutkevicius, Povilas Ignatavicius, Choy Ling Tan, Jia Yng Siaw, Sir Young Yam, Ling Wilson, Mohamed Rezal Abdul Aziz, John Bondin, Carmina Diaz Zorrilla, Anass Majbar, Danjuma Sale, Lawal Abdullahi, Olabisi Osagie, Omolara Faboya, Adedeji Fatuga, Agboola Taiwo, Emeka Nwabuoku, Marte Bliksøen, Zain Ali Khan, Jazmin Coronel, Cesar Miranda, Idelso Vasquez, Luis M. Helguero-Santin, Jennifer Rickard, Adesina Adedeji, Saleh Alqahtani, Max Rath, Michael Van Niekerk, Modise Zacharia Koto, Roel Matos-Puig, Leif Israelsson, Tobias Schuetz, Mahmut Arif Yuksek, Meric Mericliler, Mehmet Uluşahin, Bernhard Wolf, Cameron Fairfield, Guo Liang Yong, Katharine Whitehurst, Natalie Redgrave, Caroluce K. Musyoka, James Olivier, Kathryn Lee, Michael Cox, Muhamed M.H. Farhan-Alanie, Rory Callan, Chali Chibuye, Tebian Hassanein Ahmed Ali, Syrine Rekhis, Muna Rommaneh, Zi Hao Sam, Thays Brunelli Pugliesi, Gabriel Pardo, and Ruth Blanco

Subjects
abdominal surgery, cost-effectiveness analysis, global surgery, high fraction of inspired oxygen, low-and middle-income countries, surgical site infection, Anesthesiology, RD78.3-87.3
Abstract

Background: This study assessed the potential cost-effectiveness of high (80–100%) vs low (21–35%) fraction of inspired oxygen (FiO2) at preventing surgical site infections (SSIs) after abdominal surgery in Nigeria, India, and South Africa. Methods: Decision-analytic models were constructed using best available evidence sourced from unbundled data of an ongoing pilot trial assessing the effectiveness of high FiO2, published literature, and a cost survey in Nigeria, India, and South Africa. Effectiveness was measured as percentage of SSIs at 30 days after surgery, a healthcare perspective was adopted, and costs were reported in US dollars ($). Results: High FiO2 may be cost-effective (cheaper and effective). In Nigeria, the average cost for high FiO2 was $216 compared with $222 for low FiO2 leading to a −$6 (95% confidence interval [CI]: −$13 to −$1) difference in costs. In India, the average cost for high FiO2 was $184 compared with $195 for low FiO2 leading to a −$11 (95% CI: −$15 to −$6) difference in costs. In South Africa, the average cost for high FiO2 was $1164 compared with $1257 for low FiO2 leading to a −$93 (95% CI: −$132 to −$65) difference in costs. The high FiO2 arm had few SSIs, 7.33% compared with 8.38% for low FiO2, leading to a −1.05 (95% CI: −1.14 to −0.90) percentage point reduction in SSIs. Conclusion: High FiO2 could be cost-effective at preventing SSIs in the three countries but further data from large clinical trials are required to confirm this.

Published
2023
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186. New-onset atrial fibrillation following percutaneous patent foramen ovale closure: a systematic review and meta-analysis of randomised trials.

Author

Elgendy, Akram Y, Elgendy, Islam Y, Mojadidi, Mohammad K, Mahmoud, Ahmed N, Barry, Julia S, Jneid, Hani, Wayangankar, Siddharth A, Tobis, Jonathan M, and Meier, Bernhard

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Atrial Fibrillation, Foramen Ovale, Patent, Humans, Randomized Controlled Trials as Topic, Septal Occluder Device, Stroke, Statistics, Cardiovascular medicine and haematology
Published
2019

187. Incidence and Causes of 30-day Readmissions after Surgical Versus Percutaneous Secundum Atrial Septal Defect Closure: A United States Nationwide Analysis

Author

Mojadidi, Mohammad K, Mahmoud, Ahmed N, Mahtta, Dhruv, Zaman, Muhammad O, Elgendy, Islam Y, Elgendy, Akram Y, Agarwal, Nayan, Patel, Nimesh K, Gertz, Zachary M, Wayangankar, Siddharth A, Lew, David C, Jneid, Hani, Don, Creighton W, Meier, Bernhard, and Tobis, Jonathan M

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Clinical Sciences, Brain Disorders, Cardiovascular, Heart Disease, Patient Safety, Atrial septal defect, readmission rates, surgical ASD repair, percutaneous ASD-device closure
Published
2019

188. Patent Foramen Ovale and Hypoxemia

Author

Mojadidi, Mohammad K, Ruiz, Juan C, Chertoff, Jason, Zaman, Muhammad O, Elgendy, Islam Y, Mahmoud, Ahmed N, Al-Ani, Mohammad, Elgendy, Akram Y, Patel, Nimesh K, Shantha, Ghanshyam, Tobis, Jonathan M, and Meier, Bernhard

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Clinical Sciences, Clinical Research, Heart Disease, Lung, Cardiovascular, 2.1 Biological and endogenous factors, Aetiology, Endovascular Procedures, Foramen Ovale, Patent, Humans, Hypoxia, patent foramen ovale, hypoxemia, right-to-left shunt, chronic obstructive pulmonary disease, sleep apnea, platypnea-orthodeoxia, Cardiovascular System & Hematology, Cardiovascular medicine and haematology
Abstract

Patent foramen ovale (PFO), an embryonic remnant of the fetal circulation, is present in 20-25% of adults. Although recent observational studies and clinical trials have established the link between PFO-mediated right-to-left shunting with cryptogenic stroke and migraine with aura, the role of a PFO in exacerbating hypoxemic medical conditions (ie, sleep apnea, chronic obstructive pulmonary disease, pulmonary hypertension, platypnea-orthodeoxia, pulmonary arteriovenous malformation, high-altitude pulmonary edema, and exercise desaturation) remains less understood. PFO-mediated hypoxemia occurs when deoxygenated venous blood from the right atrium enters and mixes with oxygenated arterial blood in the left atrium. Patients with an intracardiac right-to-left shunt may have profound hypoxemia out of proportion to underlying primary lung disease, even in the presence of normal right-sided pressures. The presence of right-to-left cardiac shunting can exacerbate the degree of hypoxemia in patients with underlying pulmonary disorders. In a subset of these patients, percutaneous PFO closure may result in marked improvement in dyspnea and hypoxemia. This review discusses the association between PFO-mediated right-to-left shunting with medical conditions associated with hypoxemia and explores the role of percutaneous PFO closure in alleviating the hypoxemia.

Published
2019

190. Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021

Author

Ong, Kanyin Liane, Stafford, Lauryn K, McLaughlin, Susan A, Boyko, Edward J, Vollset, Stein Emil, Smith, Amanda E, Dalton, Bronte E, Duprey, Joe, Cruz, Jessica A, Hagins, Hailey, Lindstedt, Paulina A, Aali, Amirali, Abate, Yohannes Habtegiorgis, Abate, Melsew Dagne, Abbasian, Mohammadreza, Abbasi-Kangevari, Zeinab, Abbasi-Kangevari, Mohsen, Abd ElHafeez, Samar, Abd-Rabu, Rami, Abdulah, Deldar Morad, Abdullah, Abu Yousuf Md, Abedi, Vida, Abidi, Hassan, Aboagye, Richard Gyan, Abolhassani, Hassan, Abu-Gharbieh, Eman, Abu-Zaid, Ahmed, Adane, Tigist Demssew, Adane, Denberu Eshetie, Addo, Isaac Yeboah, Adegboye, Oyelola A, Adekanmbi, Victor, Adepoju, Abiola Victor, Adnani, Qorinah Estiningtyas Sakilah, Afolabi, Rotimi Felix, Agarwal, Gina, Aghdam, Zahra Babaei, Agudelo-Botero, Marcela, Aguilera Arriagada, Constanza Elizabeth, Agyemang-Duah, Williams, Ahinkorah, Bright Opoku, Ahmad, Danish, Ahmad, Rizwan, Ahmad, Sajjad, Ahmad, Aqeel, Ahmadi, Ali, Ahmadi, Keivan, Ahmed, Ayman, Ahmed, Ali, Ahmed, Luai A, Ahmed, Syed Anees, Ajami, Marjan, Akinyemi, Rufus Olusola, Al Hamad, Hanadi, Al Hasan, Syed Mahfuz, AL-Ahdal, Tareq Mohammed Ali, Alalwan, Tariq A, Al-Aly, Ziyad, AlBataineh, Mohammad T, Alcalde-Rabanal, Jacqueline Elizabeth, Alemi, Sharifullah, Ali, Hassam, Alinia, Tahereh, Aljunid, Syed Mohamed, Almustanyir, Sami, Al-Raddadi, Rajaa M, Alvis-Guzman, Nelson, Amare, Firehiwot, Ameyaw, Edward Kwabena, Amiri, Sohrab, Amusa, Ganiyu Adeniyi, Andrei, Catalina Liliana, Anjana, Ranjit Mohan, Ansar, Adnan, Ansari, Golnoosh, Ansari-Moghaddam, Alireza, Anyasodor, Anayochukwu Edward, Arabloo, Jalal, Aravkin, Aleksandr Y, Areda, Demelash, Arifin, Hidayat, Arkew, Mesay, Armocida, Benedetta, Ärnlöv, Johan, Artamonov, Anton A, Arulappan, Judie, Aruleba, Raphael Taiwo, Arumugam, Ashokan, Aryan, Zahra, Asemu, Mulu Tiruneh, Asghari-Jafarabadi, Mohammad, Askari, Elaheh, Asmelash, Daniel, Astell-Burt, Thomas, Athar, Mohammad, Athari, Seyyed Shamsadin, Atout, Maha Moh'd Wahbi, Avila-Burgos, Leticia, Awaisu, Ahmed, Azadnajafabad, Sina, B, Darshan B, Babamohamadi, Hassan, Badar, Muhammad, Badawi, Alaa, Badiye, Ashish D, Baghcheghi, Nayereh, Bagheri, Nasser, Bagherieh, Sara, Bah, Sulaiman, Bahadory, Saeed, Bai, Ruhai, Baig, Atif Amin, Baltatu, Ovidiu Constantin, Baradaran, Hamid Reza, Barchitta, Martina, Bardhan, Mainak, Barengo, Noel C, Bärnighausen, Till Winfried, Barone, Mark Thomaz Ugliara, Barone-Adesi, Francesco, Barrow, Amadou, Bashiri, Hamideh, Basiru, Afisu, Basu, Sanjay, Basu, Saurav, Batiha, Abdul-Monim Mohammad, Batra, Kavita, Bayih, Mulat Tirfie, Bayileyegn, Nebiyou Simegnew, Behnoush, Amir Hossein, Bekele, Alehegn Bekele, Belete, Melaku Ashagrie, Belgaumi, Uzma Iqbal, Belo, Luis, Bennett, Derrick A, Bensenor, Isabela M, Berhe, Kidanemaryam, Berhie, Alemshet Yirga, Bhaskar, Sonu, Bhat, Ajay Nagesh, Bhatti, Jasvinder Singh, Bikbov, Boris, Bilal, Faiq, Bintoro, Bagas Suryo, Bitaraf, Saeid, Bitra, Veera R, Bjegovic-Mikanovic, Vesna, Bodolica, Virginia, Boloor, Archith, Brauer, Michael, Brazo-Sayavera, Javier, Brenner, Hermann, Butt, Zahid A, Calina, Daniela, Campos, Luciana Aparecida, Campos-Nonato, Ismael R, Cao, Yin, Cao, Chao, Car, Josip, Carvalho, Márcia, Castañeda-Orjuela, Carlos A, Catalá-López, Ferrán, Cerin, Ester, Chadwick, Joshua, Chandrasekar, Eeshwar K, Chanie, Gashaw Sisay, Charan, Jaykaran, Chattu, Vijay Kumar, Chauhan, Kirti, Cheema, Huzaifa Ahmad, Chekol Abebe, Endeshaw, Chen, Simiao, Cherbuin, Nicolas, Chichagi, Fatemeh, Chidambaram, Saravana Babu, Cho, William C S, Choudhari, Sonali Gajanan, Chowdhury, Rajiv, Chowdhury, Enayet Karim, Chu, Dinh-Toi, Chukwu, Isaac Sunday, Chung, Sheng-Chia, Coberly, Kaleb, Columbus, Alyssa, Contreras, Daniela, Cousin, Ewerton, Criqui, Michael H, Cruz-Martins, Natália, Cuschieri, Sarah, Dabo, Bashir, Dadras, Omid, Dai, Xiaochen, Damasceno, Albertino Antonio Moura, Dandona, Rakhi, Dandona, Lalit, Das, Saswati, Dascalu, Ana Maria, Dash, Nihar Ranjan, Dashti, Mohsen, Dávila-Cervantes, Claudio Alberto, De la Cruz-Góngora, Vanessa, Debele, Gebiso Roba, Delpasand, Kourosh, Demisse, Fitsum Wolde, Demissie, Getu Debalkie, Deng, Xinlei, Denova-Gutiérrez, Edgar, Deo, Salil V, Dervišević, Emina, Desai, Hardik Dineshbhai, Desale, Aragaw Tesfaw, Dessie, Anteneh Mengist, Desta, Fikreab, Dewan, Syed Masudur Rahman, Dey, Sourav, Dhama, Kuldeep, Dhimal, Meghnath, Diao, Nancy, Diaz, Daniel, Dinu, Monica, Diress, Mengistie, Djalalinia, Shirin, Doan, Linh Phuong, Dongarwar, Deepa, dos Santos Figueiredo, Francisco Winter, Duncan, Bruce B, Dutta, Siddhartha, Dziedzic, Arkadiusz Marian, Edinur, Hisham Atan, Ekholuenetale, Michael, Ekundayo, Temitope Cyrus, Elgendy, Islam Y, Elhadi, Muhammed, El-Huneidi, Waseem, Elmeligy, Omar Abdelsadek Abdou, Elmonem, Mohamed A, Endeshaw, Destaw, Esayas, Hawi Leul, Eshetu, Habitu Birhan, Etaee, Farshid, Fadhil, Ibtihal, Fagbamigbe, Adeniyi Francis, Fahim, Ayesha, Falahi, Shahab, Faris, MoezAlIslam Ezzat Mahmoud, Farrokhpour, Hossein, Farzadfar, Farshad, Fatehizadeh, Ali, Fazli, Ghazal, Feng, Xiaoqi, Ferede, Tomas Y, Fischer, Florian, Flood, David, Forouhari, Ali, Foroumadi, Roham, Foroutan Koudehi, Masoumeh, Gaidhane, Abhay Motiramji, Gaihre, Santosh, Gaipov, Abduzhappar, Galali, Yaseen, Ganesan, Balasankar, Garcia-Gordillo, MA, Gautam, Rupesh K, Gebrehiwot, Mesfin, Gebrekidan, Kahsu Gebrekirstos, Gebremeskel, Teferi Gebru, Getacher, Lemma, Ghadirian, Fataneh, Ghamari, Seyyed-Hadi, Ghasemi Nour, Mohammad, Ghassemi, Fariba, Golechha, Mahaveer, Goleij, Pouya, Golinelli, Davide, Gopalani, Sameer Vali, Guadie, Habtamu Alganeh, Guan, Shi-Yang, Gudayu, Temesgen Worku, Guimarães, Rafael Alves, Guled, Rashid Abdi, Gupta, Rajeev, Gupta, Kartik, Gupta, Veer Bala, Gupta, Vivek Kumar, Gyawali, Bishal, Haddadi, Rasool, Hadi, Najah R, Haile, Teklehaimanot Gereziher, Hajibeygi, Ramtin, Haj-Mirzaian, Arvin, Halwani, Rabih, Hamidi, Samer, Hankey, Graeme J, Hannan, Md Abdul, Haque, Shafiul, Harandi, Hamid, Harlianto, Netanja I, Hasan, S M Mahmudul, Hasan, Syed Shahzad, Hasani, Hamidreza, Hassanipour, Soheil, Hassen, Mohammed Bheser, Haubold, Johannes, Hayat, Khezar, Heidari, Golnaz, Heidari, Mohammad, Hessami, Kamran, Hiraike, Yuta, Holla, Ramesh, Hossain, Sahadat, Hossain, Md Shakhaoat, Hosseini, Mohammad-Salar, Hosseinzadeh, Mehdi, Hosseinzadeh, Hassan, Huang, Junjie, Huda, Md Nazmul, Hussain, Salman, Huynh, Hong-Han, Hwang, Bing-Fang, Ibitoye, Segun Emmanuel, Ikeda, Nayu, Ilic, Irena M, Ilic, Milena D, Inbaraj, Leeberk Raja, Iqbal, Afrin, Islam, Sheikh Mohammed Shariful, Islam, Rakibul M, Ismail, Nahlah Elkudssiah, Iso, Hiroyasu, Isola, Gaetano, Itumalla, Ramaiah, Iwagami, Masao, Iwu, Chidozie C D, Iyamu, Ihoghosa Osamuyi, Iyasu, Assefa N, Jacob, Louis, Jafarzadeh, Abdollah, Jahrami, Haitham, Jain, Rajesh, Jaja, Chinwe, Jamalpoor, Zahra, Jamshidi, Elham, Janakiraman, Balamurugan, Jayanna, Krishnamurthy, Jayapal, Sathish Kumar, Jayaram, Shubha, Jayawardena, Ranil, Jebai, Rime, Jeong, Wonjeong, Jin, Yinzi, Jokar, Mohammad, Jonas, Jost B, Joseph, Nitin, Joseph, Abel, Joshua, Charity Ehimwenma, Joukar, Farahnaz, Jozwiak, Jacek Jerzy, Kaambwa, Billingsley, Kabir, Ali, Kabthymer, Robel Hussen, Kadashetti, Vidya, Kahe, Farima, Kalhor, Rohollah, Kandel, Himal, Karanth, Shama D, Karaye, Ibraheem M, Karkhah, Samad, Katoto, Patrick DMC, Kaur, Navjot, Kazemian, Sina, Kebede, Sewnet Adem, Khader, Yousef Saleh, Khajuria, Himanshu, Khalaji, Amirmohammad, Khan, Moien AB, Khan, Maseer, Khan, Ajmal, Khanal, Saval, Khatatbeh, Moawiah Mohammad, Khater, Amir M, Khateri, Sorour, khorashadizadeh, Fatemeh, Khubchandani, Jagdish, Kibret, Biruk Getahun, Kim, Min Seo, Kimokoti, Ruth W, Kisa, Adnan, Kivimäki, Mika, Kolahi, Ali-Asghar, Komaki, Somayeh, Kompani, Farzad, Koohestani, Hamid Reza, Korzh, Oleksii, Kostev, Karel, Kothari, Nikhil, Koyanagi, Ai, Krishan, Kewal, Krishnamoorthy, Yuvaraj, Kuate Defo, Barthelemy, Kuddus, Mohammed, Kuddus, Md Abdul, Kumar, Rakesh, Kumar, Harish, Kundu, Satyajit, Kurniasari, Maria Dyah, Kuttikkattu, Ambily, La Vecchia, Carlo, Lallukka, Tea, Larijani, Bagher, Larsson, Anders O, Latief, Kamaluddin, Lawal, Basira Kankia, Le, Thao Thi Thu, Le, Trang Thi Bich, Lee, Shaun Wen Huey, Lee, Munjae, Lee, Wei-Chen, Lee, Paul H, Lee, Sang-woong, Lee, Seung Won, Legesse, Samson Mideksa, Lenzi, Jacopo, Li, Yongze, Li, Ming-Chieh, Lim, Stephen S, Lim, Lee-Ling, Liu, Xuefeng, Liu, Chaojie, Lo, Chun-Han, Lopes, Graciliana, Lorkowski, Stefan, Lozano, Rafael, Lucchetti, Giancarlo, Maghazachi, Azzam A, Mahasha, Phetole Walter, Mahjoub, Soleiman, Mahmoud, Mansour Adam, Mahmoudi, Razzagh, Mahmoudimanesh, Marzieh, Mai, Anh Tuan, Majeed, Azeem, Majma Sanaye, Pantea, Makris, Konstantinos Christos, Malhotra, Kashish, Malik, Ahmad Azam, Malik, Iram, Mallhi, Tauqeer Hussain, Malta, Deborah Carvalho, Mamun, Abdullah A, Mansouri, Borhan, Marateb, Hamid Reza, Mardi, Parham, Martini, Santi, Martorell, Miquel, Marzo, Roy Rillera, Masoudi, Reza, Masoudi, Sahar, Mathews, Elezebeth, Maugeri, Andrea, Mazzaglia, Giampiero, Mekonnen, Teferi, Meshkat, Mahboobeh, Mestrovic, Tomislav, Miao Jonasson, Junmei, Miazgowski, Tomasz, Michalek, Irmina Maria, Minh, Le Huu Nhat, Mini, GK, Miranda, J Jaime, Mirfakhraie, Reza, Mirrakhimov, Erkin M, Mirza-Aghazadeh-Attari, Mohammad, Misganaw, Awoke, Misgina, Kebede Haile, Mishra, Manish, Moazen, Babak, Mohamed, Nouh Saad, Mohammadi, Esmaeil, Mohammadi, Mohsen, Mohammadian-Hafshejani, Abdollah, Mohammadshahi, Marita, Mohseni, Alireza, Mojiri-forushani, Hoda, Mokdad, Ali H, Momtazmanesh, Sara, Monasta, Lorenzo, Moniruzzaman, Md, Mons, Ute, Montazeri, Fateme, Moodi Ghalibaf, AmirAli, Moradi, Yousef, Moradi, Maryam, Moradi Sarabi, Mostafa, Morovatdar, Negar, Morrison, Shane Douglas, Morze, Jakub, Mossialos, Elias, Mostafavi, Ebrahim, Mueller, Ulrich Otto, Mulita, Francesk, Mulita, Admir, Murillo-Zamora, Efrén, Musa, Kamarul Imran, Mwita, Julius C, Nagaraju, Shankar Prasad, Naghavi, Mohsen, Nainu, Firzan, Nair, Tapas Sadasivan, Najmuldeen, Hastyar Hama Rashid, Nangia, Vinay, Nargus, Shumaila, Naser, Abdallah Y, Nassereldine, Hasan, Natto, Zuhair S, Nauman, Javaid, Nayak, Biswa Prakash, Ndejjo, Rawlance, Negash, Hadush, Negoi, Ruxandra Irina, Nguyen, Hau Thi Hien, Nguyen, Dang H, Nguyen, Phat Tuan, Nguyen, Van Thanh, Nguyen, Hien Quang, Niazi, Robina Khan, Nigatu, Yeshambel T, Ningrum, Dina Nur Anggraini, Nizam, Muhammad A, Nnyanzi, Lawrence Achilles, Noreen, Mamoona, Noubiap, Jean Jacques, Nzoputam, Ogochukwu Janet, Nzoputam, Chimezie Igwegbe, Oancea, Bogdan, Odogwu, Nkechi Martina, Odukoya, Oluwakemi Ololade, Ojha, Vivek Anand, Okati-Aliabad, Hassan, Okekunle, Akinkunmi Paul, Okonji, Osaretin Christabel, Okwute, Patrick Godwin, Olufadewa, Isaac Iyinoluwa, Onwujekwe, Obinna E, Ordak, Michal, Ortiz, Alberto, Osuagwu, Uchechukwu Levi, Oulhaj, Abderrahim, Owolabi, Mayowa O, Padron-Monedero, Alicia, Padubidri, Jagadish Rao, Palladino, Raffaele, Panagiotakos, Demosthenes, Panda-Jonas, Songhomitra, Pandey, Ashok, Pandey, Anamika, Pandi-Perumal, Seithikurippu R, Pantea Stoian, Anca Mihaela, Pardhan, Shahina, Parekh, Tarang, Parekh, Utsav, Pasovic, Maja, Patel, Jay, Patel, Jenil R, Paudel, Uttam, Pepito, Veincent Christian Filipino, Pereira, Marcos, Perico, Norberto, Perna, Simone, Petcu, Ionela-Roxana, Petermann-Rocha, Fanny Emily, Podder, Vivek, Postma, Maarten J, Pourali, Ghazaleh, Pourtaheri, Naeimeh, Prates, Elton Junio Sady, Qadir, Mirza Muhammad Fahd, Qattea, Ibrahim, Raee, Pourya, Rafique, Ibrar, Rahimi, Mehran, Rahimifard, Mahban, Rahimi-Movaghar, Vafa, Rahman, Md Obaidur, Rahman, Muhammad Aziz, Rahman, Mohammad Hifz Ur, Rahman, Mosiur, Rahman, Md Mosfequr, Rahmani, Mohamed, Rahmani, Shayan, Rahmanian, Vahid, Rahmawaty, Setyaningrum, Rahnavard, Niloufar, Rajbhandari, Bibek, Ram, Pradhum, Ramazanu, Sheena, Rana, Juwel, Rancic, Nemanja, Ranjha, Muhammad Modassar Ali Nawaz, Rao, Chythra R, Rapaka, Deepthi, Rasali, Drona Prakash, Rashedi, Sina, Rashedi, Vahid, Rashid, Ahmed Mustafa, Rashidi, Mohammad-Mahdi, Ratan, Zubair Ahmed, Rawaf, Salman, Rawal, Lal, Redwan, Elrashdy Moustafa Mohamed, Remuzzi, Giuseppe, Rengasamy, Kannan RR, Renzaho, Andre M N, Reyes, Luis Felipe, Rezaei, Nima, Rezaei, Nazila, Rezaeian, Mohsen, Rezazadeh, Hossein, Riahi, Seyed Mohammad, Rias, Yohanes Andy, Riaz, Muhammad, Ribeiro, Daniela, Rodrigues, Mónica, Rodriguez, Jefferson Antonio Buendia, Roever, Leonardo, Rohloff, Peter, Roshandel, Gholamreza, Roustazadeh, Abazar, Rwegerera, Godfrey M, Saad, Aly M A, Saber-Ayad, Maha Mohamed, Sabour, Siamak, Sabzmakan, Leila, Saddik, Basema, Sadeghi, Erfan, Saeed, Umar, Saeedi Moghaddam, Sahar, Safi, Sare, Safi, Sher Zaman, Saghazadeh, Amene, Saheb Sharif-Askari, Narjes, Saheb Sharif-Askari, Fatemeh, Sahebkar, Amirhossein, Sahoo, Soumya Swaroop, Sahoo, Harihar, Saif-Ur-Rahman, KM, Sajid, Mirza Rizwan, Salahi, Sarvenaz, Salahi, Saina, Saleh, Mohamed A, Salehi, Mohammad Amin, Salomon, Joshua A, Sanabria, Juan, Sanjeev, Rama Krishna, Sanmarchi, Francesco, Santric-Milicevic, Milena M, Sarasmita, Made Ary, Sargazi, Saman, Sathian, Brijesh, Sathish, Thirunavukkarasu, Sawhney, Monika, Schlaich, Markus P, Schmidt, Maria Inês, Schuermans, Art, Seidu, Abdul-Aziz, Senthil Kumar, Nachimuthu, Sepanlou, Sadaf G, Sethi, Yashendra, Seylani, Allen, Shabany, Maryam, Shafaghat, Tahereh, Shafeghat, Melika, Shafie, Mahan, Shah, Nilay S, Shahid, Samiah, Shaikh, Masood Ali, Shanawaz, Mohd, Shannawaz, Mohammed, Sharfaei, Sadaf, Shashamo, Bereket Beyene, Shiri, Rahman, Shittu, Aminu, Shivakumar, K M, Shivalli, Siddharudha, Shobeiri, Parnian, Shokri, Fereshteh, Shuval, Kerem, Sibhat, Migbar Mekonnen, Silva, Luís Manuel Lopes Rodrigues, Simpson, Colin R, Singh, Jasvinder A, Singh, Paramdeep, Singh, Surjit, Siraj, Md Shahjahan, Skryabina, Anna Aleksandrovna, Sohag, Abdullah Al Mamun, Soleimani, Hamidreza, Solikhah, Solikhah, Soltani-Zangbar, Mohammad Sadegh, Somayaji, Ranjani, Sorensen, Reed J D, Starodubova, Antonina V, Sujata, Sujata, Suleman, Muhammad, Sun, Jing, Sundström, Johan, Tabarés-Seisdedos, Rafael, Tabatabaei, Seyyed Mohammad, Tabatabaeizadeh, Seyed-Amir, Tabish, Mohammad, Taheri, Majid, Taheri, Ensiyeh, Taki, Elahe, Tamuzi, Jacques JL Lukenze, Tan, Ker-Kan, Tat, Nathan Y, Taye, Birhan Tsegaw, Temesgen, Worku Animaw, Temsah, Mohamad-Hani, Tesler, Riki, Thangaraju, Pugazhenthan, Thankappan, Kavumpurathu Raman, Thapa, Rajshree, Tharwat, Samar, Thomas, Nihal, Ticoalu, Jansje Henny Vera, Tiyuri, Amir, Tonelli, Marcello, Tovani-Palone, Marcos Roberto, Trico, Domenico, Trihandini, Indang, Tripathy, Jaya Prasad, Tromans, Samuel Joseph, Tsegay, Guesh Mebrahtom, Tualeka, Abdul Rohim, Tufa, Derara Girma, Tyrovolas, Stefanos, Ullah, Sana, Upadhyay, Era, Vahabi, Seyed Mohammad, Vaithinathan, Asokan Govindaraj, Valizadeh, Rohollah, van Daalen, Kim Robin, Vart, Priya, Varthya, Shoban Babu, Vasankari, Tommi Juhani, Vaziri, Siavash, Verma, Madhur verma, Verras, Georgios-Ioannis, Vo, Danh Cao, Wagaye, Birhanu, Waheed, Yasir, Wang, Ziyue, Wang, Yanqing, Wang, Cong, Wang, Fang, Wassie, Gizachew Tadesse, Wei, Melissa Y Wei, Weldemariam, Abrha Hailay, Westerman, Ronny, Wickramasinghe, Nuwan Darshana, Wu, YiFan, Wulandari, Ratna DWI, Xia, Juan, Xiao, Hong, Xu, Suowen, Xu, Xiaoyue, Yada, Dereje Y, Yang, Lin, Yatsuya, Hiroshi, Yesiltepe, Metin, Yi, Siyan, Yohannis, Hunachew Kibret, Yonemoto, Naohiro, You, Yuyi, Zaman, Sojib Bin, Zamora, Nelson, Zare, Iman, Zarea, Kourosh, Zarrintan, Armin, Zastrozhin, Mikhail Sergeevich, Zeru, Naod Gebrekrstos, Zhang, Zhi-Jiang, Zhong, Chenwen, Zhou, Jingjing, Zielińska, Magdalena, Zikarg, Yossef Teshome, Zodpey, Sanjay, Zoladl, Mohammad, Zou, Zhiyong, Zumla, Alimuddin, Zuniga, Yves Miel H, Magliano, Dianna J, Murray, Christopher J L, Hay, Simon I, and Vos, Theo

Published
2023
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193. Seroprevalence of SARS-CoV-2 Infection Among Working Women and Impact of Workplace Restrictions

Author

Alishaq M, Nafady-Hego H, Jeremijenko A, Al Ajmi JA, Elgendy M, Al Ansari NAA, Elgendy H, Abou-Samra AB, and Butt AA

Subjects
sars-cov-2, covid-19, work-place restrictions, women. infections, qatar., Infectious and parasitic diseases, RC109-216
Abstract

Moza Alishaq,1 Hanaa Nafady-Hego,2 Andrew Jeremijenko,3 Jameela Ali Al Ajmi,4 Mohamed Elgendy,5 Naser Ali Asad Al Ansari,4 Hamed Elgendy,4,6 Abdul-Badi Abou-Samra,1,3 Adeel A Butt4,7,8 1Department of Quality and Clinical Transformation, Hamad Medical Corporation, Doha, Qatar; 2Microbiology and Immunology Department, Faculty of Medicine, Assiut University, Assiut, Egypt; 3Department of Medicine, Hamad Medical Corporation, Doha, Qatar; 4Hamad Medical Corporation, Doha, Qatar; 5Faculty of Medicine, Universiti Sains of Malaysia, Kelantan, Malaysia; 6Anesthesia Department, Faculty of Medicine, Assiut University, Assiut, Egypt; 7Departments of Medicine and Population Health Sciences, Weill Cornell Medical College, New York, NY, USA; 8Departments of Medicine and Population Health Sciences, Weill Cornell Medical College, Doha, QatarCorrespondence: Adeel A Butt, Department of Medicine, Hamad Medical Corporation, PO Box 3050, Doha, Qatar, Email aabutt@hamad.qaObjective: To determine the prevalence of SARS-CoV-2 virus infection among female workers who were restricted to working from home compared with those who continued to attend in-person work.Methods: As part of national surveillance program, serum samples for SARS-CoV-2 antibody testing and nasopharyngeal swabs for SARS-CoV-2 PCR were obtained on 1636 female school staff and salon/spa workers who were restricted to work remotely (restricted group) and 1190 female health-care workers who continued in-person work (unrestricted group).Results: Seropositivity rate was 5.1% among the restricted and 22.7% among the unrestricted group (P < 0.0001). Presence of symptoms at baseline (adjusted odds ratio [aOR], 2.88; 95% CI 2.09– 3.97), contact with a confirmed case (aOR 2.34; 95% CI 1.37– 3.98), and unrestricted work type (aOR 4.71; 95% CI 3.24– 6.86) were associated with a higher risk of infection, while increasing age was associated with a lower risk of infection.Conclusion: Prevalence of SARS-CoV-2 infection as determined by seropositivity was higher among women who were not subject to workplace restrictions.Keywords: SARS-CoV-2, COVID-19, work-place restrictions, women, infections, Qatar

Published
2022

194. Color Filter Arrays for Quanta Image Sensors

Author

Elgendy, Omar A. and Chan, Stanley H.

Subjects
Computer Science - Computer Vision and Pattern Recognition
Abstract

Quanta image sensor (QIS) is envisioned to be the next generation image sensor after CCD and CMOS. In this paper, we discuss how to design color filter arrays for QIS and other small pixels. Designing color filter arrays for small pixels is challenging because maximizing the light efficiency while suppressing aliasing and crosstalk are conflicting tasks. We present an optimization-based framework which unifies several mainstream color filter array design methodologies. Our method offers greater generality and flexibility. Compared to existing methods, the new framework can simultaneously handle luminance sensitivity, chrominance sensitivity, cross-talk, anti-aliasing, manufacturability and orthogonality. Extensive experimental comparisons demonstrate the effectiveness of the framework.

Published
2019

195. Megapixel Photon-Counting Color Imaging using Quanta Image Sensor

Author

Gnanasambandam, Abhiram, Elgendy, Omar, Ma, Jiaju, and Chan, and Stanley H.

Subjects
Computer Science - Computer Vision and Pattern Recognition
Abstract

Quanta Image Sensor (QIS) is a single-photon detector designed for extremely low light imaging conditions. Majority of the existing QIS prototypes are monochrome based on single-photon avalanche diodes (SPAD). Passive color imaging has not been demonstrated with single-photon detectors due to the intrinsic difficulty of shrinking the pixel size and increasing the spatial resolution while maintaining acceptable intra-pixel cross-talk. In this paper, we present image reconstruction of the first color QIS with a resolution of $1024 \times 1024$ pixels, supporting both single-bit and multi-bit photon counting capability. Our color image reconstruction is enabled by a customized joint demosaicing-denoising algorithm, leveraging truncated Poisson statistics and variance stabilizing transforms. Experimental results of the new sensor and algorithm demonstrate superior color imaging performance for very low-light conditions with a mean exposure of as low as a few photons per pixel in both real and simulated images.

Published
2019
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