1,145 results on '"Dybala A."'
Search Results
152. Multiagent system for joke generation: Humor and emotions combined in human-agent conversation.
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Pawel Dybala, Michal Ptaszynski, Jacek Maciejewski, Mizuki Takahashi, Rafal Rzepka, and Kenji Araki
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- 2010
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153. Evaluating Subjective Aspects of HCI on an Example of a Non-Task Oriented Conversational System.
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Pawel Dybala, Michal Ptaszynski, Rafal Rzepka, and Kenji Araki
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- 2010
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154. CAO: A Fully Automatic Emoticon Analysis System Based on Theory of Kinesics.
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Michal Ptaszynski, Jacek Maciejewski, Pawel Dybala, Rafal Rzepka, and Kenji Araki
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- 2010
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155. Antiarrhythmic properties of phenylpiperazine derivatives of phenytoin with α1-adrenoceptor affinities
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Handzlik, Jadwiga, Bajda, Marek, Zygmunt, Małgorzata, Maciąg, Dorota, Dybała, Małgorzata, Bednarski, Marek, Filipek, Barbara, Malawska, Barbara, and Kieć-Kononowicz, Katarzyna
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- 2012
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156. Translator is Wrong!: Readers’ Attitudes towards Official Manga Translations Biased by Fan-Made Scanlations
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Pawel Dybala
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History ,business.industry ,media_common.quotation_subject ,scanlation ,translation ,fans ,Comics ,Linguistics ,Ethnology. Social and cultural anthropology ,manga ,GN301-674 ,Perception ,Criticism ,business ,Dragon Ball ,media_common - Abstract
The purpose of this paper is to investigate how the knowledge of fan-made translations (scanlations) of Japanese comics (manga) influence the perception of official translations of volumes published in Poland. An analysis is performed on readers’ comments regarding the Polish translation of the Dragon Ball Super series and can be seen as a multiple-case study, showing how readers’ attitudes can be biased by their knowledge of scanlations (in both English and Polish). Criticism is analyzed using existing translation theories and explained accordingly.
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- 2021
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157. Nesting-like band gap in bismuth sulfide Bi2S3
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F. Dybala, Szymon J. Zelewski, Robert Kudrawiec, W. M. Linhart, and P. Scharoch
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Photoluminescence ,Materials science ,Condensed matter physics ,business.industry ,Band gap ,Hydrostatic pressure ,General Chemistry ,law.invention ,Semiconductor ,Absorption edge ,law ,Solar cell ,Materials Chemistry ,Direct and indirect band gaps ,Absorption (electromagnetic radiation) ,business - Abstract
The van der Waals material Bi2S3 is a potential solar absorber, but its optoelectronic properties are not fully explored and understood. Here, using theoretical calculations and various experimental techniques under different temperature and hydrostatic pressure conditions, the optoelectronic properties of Bi2S3 are determined. The fundamental absorption edge and photoreflectance transition value has been found to be ∼1.30 eV at room temperature, which is the optimum value, giving a maximum solar cell power conversion efficiency according to the Shockley–Queisser limit for a single-junction solar cell. Temperature-dependent measurements reveal that the total energy change of the fundamental gap between 20 and 300 K is significant at ∼0.16 eV, compared to conventional semiconductors. Theoretical predictions show that Bi2S3 possesses an indirect band gap with the band nesting surrounding. The combination of experimental methods such as photoreflectance, absorption, and photoluminescence clearly shows that the direct optical transition dominates above the indirect one. Therefore, we reveal Bi2S3 as a nesting-like band gap semiconductor with a strong absorption edge and excitonic emission.
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- 2021
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158. The effect of pressure on GRIN lenses
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Piechal, Bernard, Mrozowicz, Milan, Bohdan, Roland, Dybała, Filip, and Trzeciakowski, Witold
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- 2012
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159. The Fate of Various Halogenated Organics in the Active Sites of LinB and DhaA Dehalogenases – A Combined Experimental and Computational Study
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Sowińska, Agata, primary, Rostkowski, Michał, additional, Krzemińska, Agnieszka, additional, Englman, Tzofia, additional, Gelman, Faina, additional, and Dybala-Defratyka, Agnieszka, additional
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- 2022
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160. Quantitative detection of α-Synuclein and Tau oligomers and other aggregates by digital single particle counting
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Blömeke, Lara, primary, Pils, Marlene, additional, Kraemer-Schulien, Victoria, additional, Dybala, Alexandra, additional, Schaffrath, Anja, additional, Kulawik, Andreas, additional, Rehn, Fabian, additional, Cousin, Anneliese, additional, Nischwitz, Volker, additional, Willbold, Johannes, additional, Zack, Rebecca, additional, Tropea, Thomas F., additional, Bujnicki, Tuyen, additional, Tamgüney, Gültekin, additional, Weintraub, Daniel, additional, Irwin, David, additional, Grossman, Murray, additional, Wolk, David A., additional, Trojanowski, John Q., additional, Bannach, Oliver, additional, Chen-Plotkin, Alice, additional, and Willbold, Dieter, additional
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- 2022
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161. Towards Joking, Humor Sense Equipped and Emotion Aware Conversational Systems
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Dybala, Pawel, primary, Yatsu, Motoki, additional, Ptaszynski, Michal, additional, Rzepka, Rafal, additional, and Araki, Kenji, additional
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- 2016
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162. Activating Humans with Humor - A Dialogue System That Users Want to Interact with.
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Pawel Dybala, Michal Ptaszynski, Rafal Rzepka, and Kenji Araki
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- 2009
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163. Implications of Integrated Pancreatic Microcirculation: Crosstalk between Endocrine and Exocrine Compartments
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Megan E Reyna, Lisa R Gebien, Manami Hara, Michael P. Dybala, and Yolanda Yu
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0301 basic medicine ,endocrine system ,Pathology ,medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,030209 endocrinology & metabolism ,Enteroendocrine cell ,Biology ,Microcirculation ,Islets of Langerhans ,Mice ,03 medical and health sciences ,0302 clinical medicine ,Arteriole ,medicine.artery ,Diabetes Mellitus ,Internal Medicine ,medicine ,Animals ,Humans ,Endocrine system ,geography ,geography.geographical_feature_category ,Venule ,Blood flow ,Islet ,Pancreas, Exocrine ,030104 developmental biology ,medicine.anatomical_structure ,Perspectives in Diabetes ,Pancreas - Abstract
The endocrine and exocrine pancreas have been studied separately by endocrinologists and gastroenterologists as two organ systems. The pancreatic islet, consisting of 1–2% mass of the whole pancreas, has long been believed to be regulated independently from the surrounding exocrine tissues. Particularly, islet blood flow has been consistently illustrated as one-way flow from arteriole(s) to venule(s) with no integration of the capillary network between the endocrine and exocrine pancreas. It is likely linked to the long-standing dogma that the rodent islet has a mantle of non–β-cells and that the islet is completely separated from the exocrine compartment. A new model of islet microcirculation is built on the basis of analyses of in vivo blood flow measurements in mice and an in situ three-dimensional structure of the capillary network in mice and humans. The deduced integrated blood flow throughout the entire pancreas suggests direct interactions between islet endocrine cells and surrounding cells as well as the bidirectional blood flow between the endocrine and exocrine pancreas, not necessarily a unidirectional blood flow as in a so-called insuloacinar portal system. In this perspective, we discuss how this conceptual transformation could potentially affect our current understanding of the biology, physiology, and pathogenesis of the islet and pancreas.
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- 2020
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164. The NASD Regulation Advanced Detection System (ADS).
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J. Dale Kirkland, Ted E. Senator, James J. Hayden, Tomasz Dybala, Henry G. Goldberg, and Ping Shyr
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- 1998
165. Playing the Wordle Game
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Joanne Dybala and Joanne Dybala
- Abstract
Right now, Wordle is extremely popular. What will people say years from now? "Wow, Wordle's been around that long?" Or, if the game is only a short-term fad, "What in the world is Wordle?"
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- 2022
166. A Case Report of Monkeypox in an Adult Patient from Italy: Clinical and Dermoscopic Manifestations, Diagnosis and Management
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Proietti, Ilaria, Santoro, Paolo Emilio, Skroza, Nevena, Tieghi, Tiziana, Bernardini, Nicoletta, Tolino, Ersilia, Dybala, Agnieszka Ewa, Di Guardo, Antonio, Rallo, Alessandra, Di Fraia, Marco, Rossi, Maria Francesca, Vitiello, Martina, Moscato, Umberto, Pellacani, Giovanni, Lichtner, Miriam, Potenza, Concetta, Santoro, Paolo Emilio (ORCID:0000-0002-6052-088X), Moscato, Umberto (ORCID:0000-0002-2568-3966), Proietti, Ilaria, Santoro, Paolo Emilio, Skroza, Nevena, Tieghi, Tiziana, Bernardini, Nicoletta, Tolino, Ersilia, Dybala, Agnieszka Ewa, Di Guardo, Antonio, Rallo, Alessandra, Di Fraia, Marco, Rossi, Maria Francesca, Vitiello, Martina, Moscato, Umberto, Pellacani, Giovanni, Lichtner, Miriam, Potenza, Concetta, Santoro, Paolo Emilio (ORCID:0000-0002-6052-088X), and Moscato, Umberto (ORCID:0000-0002-2568-3966)
- Abstract
Monkeypox infection is an emerging problem and a new challenge for modern medicine. With an increasing number of new cases worldwide, new data regarding the clinical manifestations, characteristics of the patients, risk factors and treatment options are coming to light. Knowing more about the disease will allow to elaborate new helpful methods to facilitate its diagnosis. Special attention should be paid to the careful dermatologic and dermoscopic examination of the patient. The analysis of available data also suggests possible strategies for the prevention of Monkeypox virus spread; the vaccine against Smallpox seems to be an effective solution. This case report describes the diagnostic approach and management of a non-vaccinated adult patient with several risk factors and a history of sexually transmitted disease. The patient had no history of travel abroad. Even though a clinical diagnose of Monkeypox can be challenging due to its similarities with skin rashes caused by other Orthopoxviral infections, there are fine differences between the rashes which can be helpful in their differentiation, although laboratory analysis is required for a definitive identification. A careful study of the characteristics of the rash, such as diameter, its presence on palms and soles and its evolution in time, provided important clues for the diagnosis of Monkeypox infection. The lack of vaccinations in the history of the patient was another crucial finding in the diagnostic process.
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- 2022
167. Central sleep apnea – a case report
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Dybala Andrzej, Dyczko Monika, Makaruk Boguslaw, Kicinski Pawel, Bartoszek Elzbieta, Myslinski Wojciech, Rahnama Mansur, and Mosiewicz Jerzy
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entral sleep apnea ,heart failure ,bipap st ,servo-ventilation ,Medicine - Abstract
Central sleep apnea (CSA) is a disease characterized by repetitive episodes of the socalled central apneas during sleep. The disease has a very complex etiology. In clinical practice, the most important causes of CSA are disorders of the central nervous system, congestive heart failure or certain pathological changes of the respiratory muscles. We present a case of a 43-year-old male with severe CSA, who was successfully treated with BiPAP ST equipment.
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- 2014
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168. Application of generative technologies in the design of reduced stiffness stems of hip joint endoprosthesis
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ŚCIGAŁA, K., BĘDZIŃSKI, R., FILIPIAK, J., CHLEBUS, E., and DYBAŁA, B.
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- 2011
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169. Microstructure and mechanical behaviour of Ti―6Al―7Nb alloy produced by selective laser melting
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Chlebus, Edward, Kuźnicka, Bogumiła, Kurzynowski, Tomasz, and Dybała, Bogdan
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- 2011
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170. Derivatives of pyrrolo[3,4- d]pyridazinone, a new class of analgesic agents
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Malinka, Wiesław, Redzicka, Aleksandra, Jastrzębska – Więsek, Magdalena, Filipek, Barbara, Dybała, Małgorzata, Karczmarzyk, Zbigniew, Urbańczyk-Lipkowska, Zofia, and Kalicki, Przemysław
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- 2011
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171. Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT1A activity. part 3
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Herold, Franciszek, Chodkowski, Andrzej, Izbicki, Łukasz, Turło, Jadwiga, Dawidowski, Maciej, Kleps, Jerzy, Nowak, Gabriel, Stachowicz, Katarzyna, Dybała, Małgorzata, Siwek, Agata, Mazurek, Aleksander P., Mazurek, Andrzej, and Pluciński, Franciszek
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- 2011
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172. Oxidative dechlorination of halogenated phenols catalyzed by two distinct enzymes: Horseradish peroxidase and dehaloperoxidase
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Szatkowski, Lukasz, Thompson, Matthew K., Kaminski, Rafal, Franzen, Stefan, and Dybala-Defratyka, Agnieszka
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- 2011
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173. Synthesis and Evaluation of in Vitro Biological Activity of 4-Substituted Arylpiperazine Derivatives of 1,7,8,9-Tetrachloro-10,10-dimethoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione
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David Collu, Roberta Loddo, Cristina Ibba, Laura Ester Marongiu, Paolo La Colla, Izabela Dybala, Anna E. Koziol, Marta Struga, Jerzy Kossakowski, and Magdalena Pakosinska-Parys
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1,7,8,9-tetrachloro-10,10-dimethoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione ,arylpiperazine derivatives ,X-ray crystal structure analysis ,antiviral activity ,Organic chemistry ,QD241-441 - Abstract
A series of twenty arylpiperazine derivatives of 1,7,8,9-tetrachloro-10,10-dimethoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione have been prepared. These derivatives were tested in vitro with the aim of identifying novel lead compounds active against emergent and re-emergent human and cattle infectious diseases (AIDS, hepatitis B and C, tuberculosis, bovine viral diarrhea). In particular, these compounds were evaluated in vitro against representatives of different virus classes, such as a HIV-1 (Retrovirus), a HBV (Hepadnavirus) and the single-stranded RNA+ viruses Yellow fever virus (YFV) and Bovine viral diarrhea virus (BVDV), both belonging to the Flaviridae. Compounds 2c, 2g and 3d showed a modest activity against CVB-2. The molecular structures of the starting imide 1 and one of propyl-piperazine derivatives, 3b, have been determined by an X-ray crystallography study.
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- 2009
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174. Coupling of Hydrogenic Tunneling to Active-Site Motion in the Hydrogen Radical Transfer Catalyzed by a Coenzyme B₁₂-Dependent Mutase
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Dybala-Defratyka, Agnieszka, Paneth, Piotr, Banerjee, Ruma, and Truhlar, Donald G.
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- 2007
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175. Revealing the unknown aspects of initial steps of prenylated flavin mononucleotide biosynthesis – the role of Lys129 in PaUbiX
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Zaczek, Szymon, primary and Dybala-Defratyka, Agnieszka, additional
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- 2022
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176. Kalker’s coefficient c11 and its influence on the damping and the retuning of a mechanical drive torsion system of a railway vehicle
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Dybala, Vojtěch, primary
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- 2022
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177. FEA study of Residual stress in composite materials in Abrasive Waterjet machining
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Balashov, Artem, primary, Dybala, Bogdan, additional, Burduk, Anna, additional, and Batako, Andre DL, additional
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- 2022
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178. Strong Substrate Strain Effects in Multilayered WS2 Revealed by High-Pressure Optical Measurements
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Oliva, Robert, primary, Wozniak, Tomasz, additional, Faria, Paulo E., additional, Dybala, Filip, additional, Kopaczek, Jan, additional, Fabian, Jaroslav, additional, Scharoch, Paweł, additional, and Kudrawiec, Robert, additional
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- 2022
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179. Storing Water for the Environment: Operating Reservoirs to Improve California’s Freshwater Ecosystems
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Null, Sarah, Mount, Jeffrey, Gray, Brian, Dybala, Kristen, Sencan, Gokce, Sturrock, Anna, Thompson, Barton, Zeff, Harrison, and Public Policy Institute of California
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constraint-based regulations ,freshwater ecosystems ,Natural Resources and Conservation ,Life Sciences ,water storage ,reservoirs ,California ,Environmental Sciences - Abstract
California’s freshwater ecosystems—its lakes, rivers, floodplains, meadows, natural and managed wetlands, and estuaries—are a vital part of the state’s natural infrastructure. These ecosystems provide numerous benefits, including water supply, hydropower, flood control, fisheries, recreation, and cultural and aesthetic value. They are also home to the nation’s most diverse array of plant and animal communities, with numerous freshwater species found only in California (Jensen et al. 1993; Grantham et al. 2017).
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- 2022
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180. Japanese Puns Are Not Necessarily Jokes.
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Pawel Dybala, Rafal Rzepka, Kenji Araki, and Kohichi Sayama
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- 2012
181. Humor, Emotions and Communication: Human-like Issues of Human-Computer Interactions.
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Pawel Dybala and Kohichi Sayama
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- 2012
182. Computing Humorous Metaphors.
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Pawel Dybala and Kohichi Sayama
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- 2012
183. Quantum Catalysis in B₁₂-Dependent Methylmalonyl-CoA Mutase: Experimental and Computational Insights
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Banerjee, Ruma, Dybala-Defratyka, Agnieszka, and Paneth, Piotr
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- 2006
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184. Revealing the unknown aspects of initial steps of prenylated flavin mononucleotide biosynthesis – the role of Lys129 in PaUbiX
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Szymon Zaczek and Agnieszka Dybala-Defratyka
- Abstract
Background Prenylated flavin mononucleotide (prFMN) is a recently discovered, heavily modified flavin compound. It is the only known cofactor that enables enzymatic 1,3-dipolar cycloaddition reactions. It is produced by enzymes from the UbiX family, from flavin mononucleotide and either dimethylallyl mono- or diphosphate. prFMN biosynthe-sis is currently reported to be initiated by protonation of the substrate by Glu140. Methods Computational chemistry methods are applied herein - mostly different flavors of molecular dynamics MD, such as Constant pH MD, hybrid Quantum-Mechanical / Molecular Mechanical MD, and classical MD. Results Glu140 competes for a single proton with Lys129 prior to the prFMN biosynthesis but it is the latter that adopted a protonated state throughout most of the simulation time. Lys129 interacts very strongly with Glu140 and it plays a key role in the positioning of the DMAP’s phosphate group within the PaUbiX active site throughout different steps of prFMN biosynthesis Conclusions The role of Lys129 in the functioning of PaUbiX is reported for the first time. The severity of interactions between Glu140, Lys129, and DMAP’s phosphate group might enable an unusual decoupling of phosphate’s protonation from the DMAP’s breakdown. This behavior is most likely conserved throughout the UbiX family to the structur-al resemblance of active sites of those proteins. Significance Mechanistic insights into a crucial biochemical process, biosynthesis of prFMN, are provided. This study, alt-hough purely computational, extends and perfectly complements the knowledge obtained in classical laboratory experiments.
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- 2021
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185. Isotope Effects on the Vaporization of Organic Compounds from an Aqueous Solution-Insight from Experiment and Computations
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Michał Rostkowski, Heide K. V. Schürner, Agata Sowińska, Luis Vasquez, Martyna Przydacz, Martin Elsner, and Agnieszka Dybala-Defratyka
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Carbon Isotopes ,Materials Chemistry ,Water ,Physical and Theoretical Chemistry ,Chemical Fractionation ,Volatilization ,Groundwater ,Article ,Surfaces, Coatings and Films - Abstract
An isotope fractionation analysis of organic groundwater pollutants can assess the remediation at contaminated sites yet needs to consider physical processes as potentially confounding factors. This study explores the predictability of water–air partitioning isotope effects from experiments and computational predictions for benzene and trimethylamine (both H-bond acceptors) as well as chloroform (H-bond donor). A small, but significant, isotope fractionation of different direction and magnitude was measured with ε = −0.12‰ ± 0.07‰ (benzene), εC = 0.49‰ ± 0.23‰ (triethylamine), and εH = 1.79‰ ± 0.54‰ (chloroform) demonstrating that effects do not correlate with expected hydrogen-bond functionalities. Computations revealed that the overall isotope effect arises from contributions of different nature and extent: a weakening of intramolecular vibrations in the condensed phase plus additional vibrational modes from a complexation with surrounding water molecules. Subtle changes in benzene contrast with a stronger coupling between intra- and intermolecular modes in the chloroform–water system and a very local vibrational response with few atoms involved in a specific mode of triethylamine. An energy decomposition analysis revealed that each system was affected differently by electrostatics and dispersion, where dispersion was dominant for benzene and electrostatics dominated for chloroform and triethylamine. Interestingly, overall stabilization patterns in all studied systems originated from contributions of dispersion rather than other energy terms.
- Published
- 2021
186. Exome Sequencing Reveals Novel Variants and Expands the Genetic Landscape for Congenital Microcephaly
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Mateusz Dawidziuk, Tomasz Gambin, Ewelina Bukowska-Olech, Dorota Antczak-Marach, Magdalena Badura-Stronka, Piotr Buda, Edyta Budzynska, Jennifer Castaneda, Tatiana Chilarska, Elzbieta Czyzyk, Anna Eckersdorf-Mastalerz, Jolanta Fijak-Moskal, Dorota Gieruszczak-Bialek, Ewelina Glodek-Brzozowska, Alicja Goszczanska-Ciuchta, Malgorzata Grzeszykowska-Podymniak, Barbara Gurda, Anna Jakubiuk-Tomaszuk, Ewa Jamroz, Magdalena Janeczko, Dominika Jedlińska-Pijanowska, Marta Jurek, Dagmara Karolewska, Adela Kazmierczak, Teresa Kleist, Iwona Kochanowska, Malgorzata Krajewska-Walasek, Katarzyna Kufel, Anna Kutkowska-Kaźmierczak, Agata Lipiec, Dorota Maksym-Gasiorek, Anna Materna-Kiryluk, Hanna Mazurkiewicz, Michał Milewski, Tatsiana Pavina-Guglas, Aleksandra Pietrzyk, Renata Posmyk, Antoni Pyrkosz, Mariola Rudzka-Dybala, Ryszard Slezak, Marzena Wisniewska, Zofia Zalewska-Miszkurka, Elzbieta Szczepanik, Ewa Obersztyn, Monika Bekiesinska-Figatowska, Pawel Gawlinski, and Wojciech Wiszniewski
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Male ,medical genetics ,Adolescent ,neurology ,Infant, Newborn ,Infant ,human genetics ,Sequence Analysis, DNA ,QH426-470 ,Article ,Pedigree ,Child, Preschool ,Mutation ,Exome Sequencing ,molecular genetics ,Microcephaly ,Genetics ,Humans ,Female ,Gene Regulatory Networks ,high-throughput nucleotide sequencing ,Child ,Genetics (clinical) - Abstract
Congenital microcephaly causes smaller than average head circumference relative to age, sex and ethnicity and is most usually associated with a variety of neurodevelopmental disorders. The underlying etiology is highly heterogeneous and can be either environmental or genetic. Disruption of any one of multiple biological processes, such as those underlying neurogenesis, cell cycle and division, DNA repair or transcription regulation, can result in microcephaly. This etiological heterogeneity manifests in a clinical variability and presents a major diagnostic and therapeutic challenge, leaving an unacceptably large proportion of over half of microcephaly patients without molecular diagnosis. To elucidate the clinical and genetic landscapes of congenital microcephaly, we sequenced the exomes of 191 clinically diagnosed patients with microcephaly as one of the features. We established a molecular basis for microcephaly in 71 patients (37%), and detected novel variants in five high confidence candidate genes previously unassociated with this condition. We report a large number of patients with mutations in tubulin-related genes in our cohort as well as higher incidence of pathogenic mutations in MCPH genes. Our study expands the phenotypic and genetic landscape of microcephaly, facilitating differential clinical diagnoses for disorders associated with most commonly disrupted genes in our cohort.
- Published
- 2021
187. Characteristics of patients with atrial fibrillation prescribed antiplatelet monotherapy compared with those on anticoagulants: insights from the GARFIELD-AF registry
- Author
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Kania, G., Kakkar, Ajay K., Kayani, Gloria, Camm, A. John, Bassand, Jean-Pierre, Gao, Haiyan, Worthy, V, Verdi, C., Tripti, T., Treasure, L., Thompson, N., Theobald, H., Thatcher, A., Stephanie, B., Smith, K., Shoemaker, J., Shaw, P., Sanghera, T., Sage, A., Robertson, C., Richardson, T., Richard, C., Raziano, S., Raynor, J., Purcell, T., Pickelsimer, N., Peterson, J., Pearl, G., Paserchia, S., Parrott, T., Parker, M., Palumbo, V, Orosco, C., Mooso, B., Minardo, J., Merritt, D., Merliss, A., Malone, E., Lincoln, T., Lee, J. A., Lay, M., Langdon, J., Knowles, P., Kerr, J., Keeling, M., Karl, S., Jones, P., Jones, L., Jones, A., Jasinski, S., Hicks, T., Herrick, C., Henson, L., Headlee, M., Hawkins, B., Hartranft, E., Harbour, T., Hakimi, F., Haideri, A., Gentry, P., Fielder, D., Ferdinand, K., Felpel, S., Evans, L., Eley, M., Dickerson, A., DePauw, J., Congal, S., Cervellione, K., Cassidy, D., Canova, M., Cameron-Watts, J., Browne, A., Brown, A., Bowers, S., Bentley, M., Bartlett, M., Ball, K., Asafu-Adjaye, N., Treasure, C., Nishijima, D., Pitta, S., Duffy, P., Noveck, H., Ison, R., Alberts, M., Remmel, K., Theodoro, D., Diercks, D., Delafontaine, P., Ahmed, W., Reddy, R., Haque, I, Gutowski, T., Alfieri, A., Beach, S., Miller, S., Williams, M., Mendelson, R., Falkowski, S., Franco, M., Cox, M., Kutayli, W. M., Ferrick, K., Quick, A., Wilson, V, Mullen, P., Garcia, J., Blumberg, E., Rama, P., Canosa, R., Goldhaber, S. Z., Thanzeel, M., Sharma, R., Sharma, N., Mohamed, R., Maqsood, I, Makdad, M., Magdaluyo, K., Jadhav, S., Haridas, P., El Bardisy, S., Al Mulla, A., Abdul, A., Subbaraman, B., Khan, M., Gupta, R., Wassef, A., Bazargani, N., Maruthanayagam, R., Al Naeemi, A., Al Omairi, M., Abu-Mahfouz, M., Naguib, A., Singh, R., Esheiba, E. M., Ibrahim, M., Nathani, M., Agrawal, A., Yousef, G., Al Mahmeed, W., van Zyl, F., Tau, T., Tarr, G., Smith, L., Skein, A., Shaik, F., Sasto, J., Salie, M., Rikhotso, L., Page, A., Mostert, M., Mavhusa, L., Marks, J., Loyd, E., Karsten, M., Henley, L., Ellis, T., Du Plessis, G., de Meyer, L., Khairy, T., Katta, A., Elkhadem, M., El-Etreby, A., Elbahry, A., El Etriby, S., El Din, M. G., Abou Seif, S. K., Abd El-Aziz, A., Ragy, H., Wright, D., Wong, S., Trahey, T., Stevenson, J., Spearson, S., Snell, L., Schulman, S., Sas, G., Robinson, M., Roberts, P., Raines, M., Pinter, A., Petrie, F., Pandey, M., Otis, R., Otis, J., Neas, I, Navratil, J., Moor, R., Mangat, I, Lewis, S., Lewis, C., Largy, J., Kwan, L., Kornder, J., Korley, V, Kim, R., Kelly, S., Kahlon, R., Jethoo, G., Jean, C., Jackson, A. 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N., Oh, S., Yeo, C., Yap, S. Y., Thng, S., Lim, W. T., Lim, G., Lee, Y. M., Norita, H., Chiba, K., Adachi, S., Shiraishi, K., Oda, H. (Hiroshi), Minamoto, M., Suetsugu, T., Ando, S., Noguchi, H., Misumi, I, Mizuno, Y., Toyota, F., Sadamatsu, K., Katsuda, Y., Kumagai, K., Yamamoto, K., Kanamori, S., Koretsune, Y., Panse, S. G., Vanajakshamma, V., Suresh, S., Singhal, S., Shiva, P., Sharma, M., Shah, D., Sadhu, N., Rao, N. M., Rao, M., Prashanth, K., Naik, D., More, P., Meena, R., Madarkar, N., Lokesh, B., Lawande, A., Krishnappa, S., Kaur, S., Kasala, L., Karthikeyan, R., Jain, V, Giradkar, S., Ganatra, A., Earath, M., Duhan, S., Dhyani, V, Dhakrao, P., Deshpande, B., Davies, D., Dargude, M., Bhattacharjee, P., Begum, H., Barai, A., Adak, D., Abraham, S., Jain, D., Kumar, S., Gupta, J. B., Khan, A., Bisne, V, Bantwal, G., Vijan, V. M., Vijayaraghavan, G., Raghuraman, B., Kothiwale, V. A., Chawla, K., Shah, S., Purayil, M. Padinhare, Pothiwala, R. A., Chandwani, P., Kulkarni, G., Kishore, R., Chopda, M., Nagamalesh, U. M., Roy, D., Srinivas, A., Sarma, R., Bhargava, K., Rajput, R. K., Shankar, A. G. Ravi, Durgaprasad, R., Jadhav, P., Sawhney, J. P. S., Kakkar, S., Zhu, X. Y., Zhao, Y. S., Chen, K. N., Hu, D. Y., Fitzmaurice, David, Al Mahmeed, Wael, Parkhomenko, Alex, Oto, Ali, Angchaisuksiri, Pantep, Steffel, Jan, Rosenqvist, Marten, Vinolas, Xavier, Oh, Seil, Jacobson, Barry, Lim, Toon Wei, Panchenko, Elizaveta, Stepinska, Janina, Atar, Dan, Ten Cate, Hugo, Sanchez Diaz, Carlos Jerjes, Koretsune, Yukihiro, Agnelli, Giancarlo, Sawhney, Jitendra Pal Singh, Kakkar, Sanjay, Keltai, Matyas, Darius, Harald, Le Heuzey, Jean-Yves, Raatikainen, Pekka, Ragy, Hany, Nielsen, Jorn Dalsgaard, Jansky, Petr, Hu, Dayi, Corbalan, Ramon, Eikelboom, John, Spyropoulos, Alex, Connolly, Stuart J., Pereira Barretto, Antonio Carlos, Cools, Frank, Brodmann, Marianne, Gibbs, Harry, Lucas Luciardi, Hector, van Eickels, Martin, Pieper, Karen S., Misselwitz, Frank, Yilmaz, MEHMET BİRHAN, Ambrosio, Giuseppe, Verheugt, Freek W. A., Boveda, S., Cebron, J-P, Delarche, N., Piot, O., Destrac, S., Marquand, A., Koujan, M. B., Muller, J-J, Loiselet, P., Paganelli, F., Gottwalles, Y., Galinier, M., Le Heuzey, J-Y, Vasankari, T., Rasanen, V, Peltomaki, K., Nappila, H., Inoue, T., Inaba, H., Imaizumi, M., Ikeoka, K., Ikeda, K., Ikeda, H., Iiji, O., Ido, T., Horie, H. (Hideki), Honda, M., Hirota, S., Hirose, M., Hirayama, H., Hirasawa, K., Higuchi, K., Hayashi, Y., Hatsuno, T., Hasegawa, K., Hanazono, N., Hamaoka, M., Goto, T., Furumoto, W., Furukawa, T., Furukawa, N., Fukui, T., Fukuda, T., Fujisawa, Y., Fujisawa, A., Fujiki, R., Fujii, Y., Endo, M., Emura, Y., Doiuchi, J., Date, H., Chibana, H., Betsuyaku, T., Baba, T., Azuma, J., Asano, T., Asano, H., Arino, T., Arima, S., Arai, H., Aoyama, T., Aoki, K., Amano, T., Akahane, K., Adachi, T., Adachi, S. (Susumu), Adachi, S. (Sen), Abe, Y., Nagasaka, S., Okuda, F., Mukawa, H., Wada, M., Minagawa, T., Ishiguro, M., Mizuguchi, M., Yoshida, T. (Tomoki), Yoshida, T. (Tetsuro), Neya, K., Soma, A., Shiga, Y. (Yukio), Sugishita, N., Horie, H. 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H., Tian, G., Wang, K., Wang, L., Wu, R. N., Xie, Q., Xu, R. Y., Yang, J. S., Yang, L. L., Yang, Q., Ye, Y., Yu, H. Y., Yu, J. H., Yu, T., Zhai, H., Zhan, Q., Zhang, G. S., Zhang, Q., Zhang, R., Zhang, Y., Zheng, W. Y., Zhou, B., Zhou, Z. H., Zhu, X. Y., Jadhav, P., Durgaprasad, R., Ravi Shankar, A. G., Rajput, R. K., Bhargava, K., Sarma, R., Srinivas, A., Roy, D., Nagamalesh, U. M., Chopda, M., Kishore, R., Kulkarni, G., Chandwani, P., Pothiwala, R. A., Purayil, M. P., Shah, S., Chawla, K., Kothiwale, V. A., Raghuraman, B., Vijayaraghavan, G., Vijan, V. M., Bantwal, G., Bisne, V., Khan, A., Gupta, J. B., Kumar, S., Jain, D., Abraham, S., Adak, D., Barai, A., Begum, H., Bhattacharjee, P., Dargude, M., Davies, D., Deshpande, B., Dhakrao, P., Dhyani, V., Duhan, S., Earath, M., Ganatra, A., Giradkar, S., Jain, V., Karthikeyan, R., Kasala, L., Kaur, S., Krishnappa, S., Lawande, A., Lokesh, B., Madarkar, N., Meena, R., More, P., Naik, D., Prashanth, K., Rao, M., Rao, N. M., Sadhu, N., Shah, D., Sharma, M., Shiva, P., Singhal, S., Suresh, S., Vanajakshamma, V., Panse, S. G., Kanamori, S., Yamamoto, K., Kumagai, K., Katsuda, Y., Sadamatsu, K., Toyota, F., Mizuno, Y., Misumi, I., Noguchi, H., Ando, S., Suetsugu, T., Minamoto, M., Oda, H., Shiraishi, K., Adachi, S., Chiba, K., Norita, H., Tsuruta, M., Koyanagi, T., Ando, H., Higashi, T., Okada, K., Azakami, S., Komaki, S., Kumeda, K., Murayama, T., Matsumura, J., Oba, Y., Sonoda, R., Goto, K., Minoda, K., Haraguchi, Y., Suefuji, H., Miyagi, H., Kato, H., Nakamura, T., Nandate, H., Zaitsu, R., Fujiura, Y., Yoshimura, A., Numata, H., Ogawa, J., Tatematsu, H., Kamogawa, Y., Murakami, K., Wakasa, Y., Yamasawa, M., Maekawa, H., Abe, S., Kihara, H., Tsunoda, S., Saito, K., Fudo, T., Obunai, K., Tachibana, H., Oba, I., Kuwahata, T., Higa, S., Gushiken, M., Eto, T., Yoshida, H., Ikeda, D., Ishizawa, M., Nakatsuka, M., Murata, K., Ogurusu, C., Shimoyama, M., Akutsu, M., Takamura, I., Hoshino, F., Yokota, N., Iwao, T., Tsuchida, K., Takeuchi, M., Hatori, Y., Kitami, Y., Nakamura, Y., Oyama, R., Ageta, M., Go, Y., Mishima, K., Unoki, T., Morii, S., Shiga, Y., Sumi, H., Nagatomo, T., Sanno, K., Fujisawa, K., Atsuchi, Y., Nagoshi, T., Seto, T., Tabuchi, T., Kameko, M., Nii, K., Oshiro, K., Takezawa, H., Nagano, S., Miyamoto, N., Iwaki, M., Fujii, M., Okawa, M., Abe, M., Saito, T., Mito, T., Nagao, K., Minami, J., Mita, T., Sakuma, I., Taguchi, T., Marusaki, S., Doi, H., Tanaka, M., Fujito, T., Matsuta, M., Kusumoto, T., Kakinoki, S., Ashida, K., Yoshizawa, N., Agata, J., Arasaki, O., Manita, M., Ikemura, M., Fukuoka, S., Murakami, H., Matsukawa, S., Hata, Y., Taniguchi, T., Ko, T., Kubo, H., Imamaki, M., Akiyama, M., Inagaki, M., Odakura, H., Ueda, T., Katsube, Y., Nakata, A., Watanabe, H., Techigawara, M., Igarashi, M., Taga, K., Kimura, T., Tomimoto, S., Shibuya, M., Nakano, M., Ito, K., Seo, T., Hiramitsu, S., Hosokawa, H., Hoshiai, M., Hibino, M., Miyagawa, K., Horie, H., Sugishita, N., Soma, A., Neya, K., Yoshida, T., Mizuguchi, M., Ishiguro, M., Minagawa, T., Wada, M., Mukawa, H., Okuda, F., Nagasaka, S., Abe, Y., Adachi, T., Akahane, K., Amano, T., Aoki, K., Aoyama, T., Arai, H., Arima, S., Arino, T., Asano, H., Asano, T., Azuma, J., Baba, T., Betsuyaku, T., Chibana, H., Date, H., Doiuchi, J., Emura, Y., Endo, M., Fujii, Y., Fujiki, R., Fujisawa, A., Fujisawa, Y., Fukuda, T., Fukui, T., Furukawa, N., Furukawa, T., Furumoto, W., Goto, T., Hamaoka, M., Hanazono, N., Hasegawa, K., Hatsuno, T., Hayashi, Y., Higuchi, K., Hirasawa, K., Hirayama, H., Hirose, M., Hirota, S., Honda, M., Ido, T., Iiji, O., Ikeda, H., Ikeda, K., Ikeoka, K., Imaizumi, M., Inaba, H., Inoue, T., Iseki, F., Ishihara, A., Ishioka, N., Ito, N., Iwase, T., Kakuda, H., Kamata, J., Kanai, H., Kanda, H., Kaneko, M., Kano, H., Kasai, T., Kato, T., Kato, Y., Kawada, Y., Kawai, K., Kawakami, K., Kawakami, S., Kawamoto, T., Kawano, S., Kim, J., Kira, T., Kitazawa, H., Kitazumi, H., Kito, T., Kobayashi, T., Koeda, T., Kojima, J., Komatsu, H., Komatsu, I., Koshibu, Y., Kotani, T., Kozuka, T., Kumai, Y., Kumazaki, T., Maeda, I., Maeda, K., Maruyama, Y., Matsui, S., Matsushita, K., Matsuura, Y., Mineoi, K., Mitsuhashi, H., Miura, N., Miyaguchi, S., Miyajima, S., Miyamoto, H., Miyashita, A., Miyata, S., Mizuguchi, I., Mizuno, A., Mori, T., Moriai, O., Morishita, K., Murai, O., Nagai, S., Nagata, E., Nagata, H., Nakagomi, A., Nakahara, S., Nakamura, M., Nakamura, R., Nakanishi, N., Nakayama, T., Nakazato, R., Nanke, T., Nariyama, J., Niijima, Y., Niinuma, H., Nishida, Y., Nishihata, Y., Nishino, K., Nishioka, H., Nishizawa, K., Niwa, I., Nomura, K., Nomura, S., Nozoe, M., Ogawa, T., Ohara, N., Okada, M., Okamoto, K., Okita, H., Okuyama, M., Ono, H., Ono, T., Pearce, Y. 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T., Thng, S., Yap, S. Y., Yeo, C., Pak, H. N., Kim, J. -B., Kim, J. H., Jang, S. -W., Kim, D. H., Ryu, D. R., Park, S. W., Kim, D. -K., Choi, D. J., Oh, Y. S., Cho, M. -C., Kim, S. -H., Jeon, H. -K., Shin, D. -G., Park, J. S., Park, H. K., Han, S. -J., Sung, J. H., Cho, J. -G., Nam, G. -B., On, Y. K., Lim, H. E., Kwak, J. J., Cha, T. -J., Hong, T. J., Park, S. H., Yoon, J. H., Kim, N. -H., Kim, K. -S., Jung, B. C., Hwang, G. -S., Kim, C. -J., Kim, D. B., Ahn, J. J., An, H. J., Bae, H., Baek, A. L., Chi, W. J., Choi, E. A., Choi, E. H., Choi, H. K., Choi, H. S., Han, S., Heo, E. S., Her, K. O., Hwang, S. W., Jang, E. M., Jang, H. -S., Jang, S., Jeon, H. -G., Jeon, S. R., Jeon, Y. R., Jeong, H. K., Jung, I. -A., Kim, H. J., Kim, J. S., Kim, J. A., Kim, K. T., Kim, M. S., Kim, S. H., Kim, Y. -I., Lee, C. S., Lee, E. H., Lee, G. H., Lee, H. Y., Lee, H. -Y., Lee, K. H., Lee, K. R., Lee, M. S., Lee, M. -Y., Lee, R. W., Lee, S. E., Lee, S. H., Lee, S., Lee, W. Y., Noh, I. K., Park, A. 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A, Colquhoun, D, Kiat, H, Eccleston, D, French, J, Zimmett, L, Ayres, B, Phan, T, Blombery, P, Crimmins, D, O'Donnell, D, Choi, A, Astridge, P, Arstall, M, Jepson, N, Binnekamp, M, Lee, A, Rogers, J, Starmer, G, Carroll, P, Faunt, J, Aggarwala, A, Barry, L, Batta, C, Beveridge, R, Black, A, Bonner, M, Boys, J, Buckley, E, Campo, M, Carlton, L, Connelly, A, Conway, B, Cresp, D, Dimitri, H, Dixon, S, Dolman, M, Duroux, M, Eskandari, M, Eslick, R, Ferreira-Jardim, A, Fetahovic, T, Fitzpatrick, D, Geraghty, R, Gibbs, J, Grabek, T, Modi, M, Hayes, K, Hegde, M, Hesketh, L, Hoffmann, B, Johnson, K, Juergens, C, Kassam, I, Lawlor, V, Lehman, M, Lehman, S, Leung, D, Mackay, S, Mackenzie, M, Mccarthy, C, Mcintosh, C, Mckeon, L, Morrison, H, Mussap, C, Myers, J, Nagalingam, V, Oldfield, G, O'May, V, Palmer, J, Parsons, L, Patching, K, Patching, T, Paul, V, Plotz, M, Preston, S, Rashad, H, Ratcliffe, M, Raynes, S, Rose, J, Sanders, L, Seremetkoska, M, Setio, H, Shone, S, Shrestha, P, Singh, C, Singleton, C, Stoyanov, N, Sutcliffe, S, Swaraj, K, Tarrant, J, Thompson, S, Tsay, I, Vorster, M, Waldman, A, Wallis, L, Wilford, E, Won, G, Luton, R, Gupta, M, Pandey, A, Cheung, S, Leader, R, Beaudry, P, Ayala-Paredes, F, Berlingieri, J, Heath, J, Poirier, G, Du Preez, M, Nadeau, R, Dresser, G, Dhillon, R, Hruczkowski, T, Schweitzer, B, Coutu, B, Angaran, P, Macdonald, P, Vizel, S, Fikry, S, Parkash, R, Lavoie, A, Cha, J, Ramjattan, B, Bonet, J, Ahmad, K, Aro, L, Aves, T, Beaudry, K, Bergeron, C, Bigcanoe, J, Bignell, N, Breakwell, L, Burke, E, Carroll, L, Clarke, B, Cleveland, T, Daheb, S, Dehghani, P, Denis, I, Djaidani, Z, Dorian, P, Douglass, S, Dunnigan, J, Ewert, A, Farquhar, D, Fearon, A, Ferleyko, L, Fournier, D, Fox, B, Grenier, M, Gulliver, W, Haveman, K, Hines, C, Hines, K, Jackson, A, Jean, C, Jethoo, G, Kahlon, R, Kelly, S, Kim, R, Korley, V, Kornder, J, Kwan, L, Largy, J, Lewis, C, Lewis, S, Mangat, I, Moor, R, Navratil, J, Neas, I, Otis, J, Otis, R, Pandey, M, Petrie, F, Pinter, A, Raines, M, Roberts, P, Robinson, M, Sas, G, Schulman, S, Snell, L, Spearson, S, Stevenson, J, Trahey, T, Wrigh, T, Abd El-Aziz, A, Seif, S, El Din, M, El Etriby, S, Elbahry, A, El-Etreby, A, Elkhadem, M, Katta, A, Khairy, T, Mowafy, A, Nawar, M, Ohanissian, A, Reda, A, Reda, M, Salem, H, Sami, N, Samir, S, Setiha, M, Sobhy, M, Soliman, A, Taha, N, Tawfik, M, Zaatout, E, Kettles, D, Bayat, J, Siebert, H, Horak, A, Kelfkens, Y, Garda, R, Pillay, T, Guerra, M, van Zyl, L, Theron, H, Murray, A, Louw, R, Greyling, D, Mntla, P, Ueckermann, V, Loghdey, R, Ismail, S, Ahmed, F, Engelbrecht, J, Ramdass, A, Maharajh, S, Oosthuysen, W, Angel, G, Bester, C, Booysen, M, Boshoff, C, Cannon, C, Cassimjee, S, Chami, C, Conway, G, Davids, A, de Meyer, L, Du Plessis, G, Ellis, T, Henley, L, Karsten, M, Loyd, E, Marks, J, Mavhusa, L, Mostert, M, Page, A, Rikhotso, L, Salie, M, Sasto, J, Shaik, F, Skein, A, Smith, L, Tarr, G, Tau, T, van Zyl, F, Yousef, G, Agrawal, A, Nathani, M, Ibrahim, M, Esheiba, E, Singh, R, Naguib, A, Abu-Mahfouz, M, Al Omairi, M, Al Naeemi, A, Maruthanayagam, R, Bazargani, N, Wassef, A, Gupta, R, Khan, M, Subbaraman, B, Abdul, A, Al Mulla, A, El Bardisy, S, Haridas, P, Jadhav, S, Magdaluyo, K, Makdad, M, Maqsood, I, Mohamed, R, Sharma, N, Sharma, R, Thanzeel, M, Canosa, R, Rama, P, Blumberg, E, Garcia, J, Mullen, P, Wilson, V, Quick, A, Ferrick, K, Kutayli, W, Cox, M, Franco, M, Falkowski, S, Mendelson, R, Williams, M, Miller, S, Beach, S, Alfieri, A, Gutowski, T, Haque, I, Reddy, R, Ahmed, W, Delafontaine, P, Diercks, D, Theodoro, D, Remmel, K, Alberts, M, Ison, R, Noveck, H, Duffy, P, Pitta, S, Nishijima, D, Treasure, C, Asafu-Adjaye, N, Ball, K, Bartlett, M, Bentley, M, Bowers, S, Brown, A, Browne, A, Cameron-Watts, J, Canova, M, Cassidy, D, Cervellione, K, Congal, S, Depauw, J, Dickerson, A, Eley, M, Evans, L, Felpel, S, Ferdinand, K, Fielder, D, Gentry, P, Haideri, A, Hakimi, F, Harbour, T, Hartranft, E, Hawkins, B, Headlee, M, Henson, L, Herrick, C, Hicks, T, Jasinski, S, Jones, A, Jones, L, Jones, P, Karl, S, Keeling, M, Kerr, J, Knowles, P, Langdon, J, Lay, M, Lee, J, Lincoln, T, Malone, E, Merliss, A, Merritt, D, Minardo, J, Mooso, B, Orosco, C, Palumbo, V, Parker, M, Parrott, T, Paserchia, S, Pearl, G, Peterson, J, Pickelsimer, N, Purcell, T, Raynor, J, Raziano, S, Richard, C, Richardson, T, Robertson, C, Sage, A, Sanghera, T, Shaw, P, Shoemaker, J, Smith, K, Stephanie, B, Thatcher, A, Theobald, H, Thompson, N, Treasure, L, Tripti, T, Verdi, C, and Worthy, V
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Male ,medicine.medical_specialty ,Vascular damage Radboud Institute for Health Sciences [Radboudumc 16] ,030204 cardiovascular system & hematology ,Coronary artery disease ,03 medical and health sciences ,Anticoagulant therapy, Antiplatelet therapy, Atrial fibrillation ,0302 clinical medicine ,Risk Factors ,Internal medicine ,Antithrombotic ,Atrial Fibrillation ,medicine ,Humans ,030212 general & internal medicine ,Prospective Studies ,Anticoagulant therapy ,Aged ,Vascular disease ,business.industry ,Antiplatelet therapy ,Platelet Aggregation Inhibitor ,Risk Factor ,Atrial fibrillation ,Anticoagulant ,Anticoagulants ,Odds ratio ,ta3121 ,Middle Aged ,medicine.disease ,Prospective Studie ,Embolism ,Cohort ,Female ,Cardiology and Cardiovascular Medicine ,business ,Fibrinolytic agent ,Platelet Aggregation Inhibitors ,Human - Abstract
Contains fulltext : 190411.pdf (Publisher’s version ) (Closed access) Aims: Current atrial fibrillation (AF) guidelines discourage antiplatelet (AP) monotherapy as alternative to anticoagulants (ACs). Why AP only is still used is largely unknown. Methods and results: Factors associated with AP monotherapy prescription were analysed in GARFIELD-AF, a registry of patients with newly diagnosed (/=1 investigator-determined stroke risk factor. We analysed 51 270 patients from 35 countries enrolled into five sequential cohorts between 2010 and 2016. Overall, 20.7% of patients received AP monotherapy, 52.1% AC monotherapy, and 14.1% AP + AC. Most AP monotherapy (82.5%) and AC monotherapy (86.8%) patients were CHA2DS2-VASc >/=2. Compared with patients on AC monotherapy, AP monotherapy patients were frequently Chinese (vs. Caucasian, odds ratio 2.73) and more likely to have persistent AF (1.32), history of coronary artery disease (2.41) or other vascular disease (1.67), bleeding (2.11), or dementia (1.81). The odds for AP monotherapy increased with 5 years of age increments for patients >/=75 years (1.24) but decreased with age increments for patients 55-75 years (0.86). Antiplatelet monotherapy patients were less likely to have paroxysmal (0.67) or permanent AF (0.57), history of embolism (0.56), or alcohol use (0.90). With each cohort, AP monotherapy declined (P/=2). Conclusion: Prescribing AP monotherapy in newly diagnosed AF has declined, but even nowadays a substantial proportion of AP-treated patients with AF have no indication for AP. Clinical Trial Registration: URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362.
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- 2018
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188. Simile or Not Simile?
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Dybala, Pawel, primary, Rzepka, Rafal, additional, Araki, Kenji, additional, and Sayama, Kohichi, additional
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- 2016
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189. Synthesis and pharmacological evaluation of new 5-(cyclo)alkyl-5-phenyl- and 5-spiroimidazolidine-2,4-dione derivatives. Novel 5-HT 1A receptor agonist with potential antidepressant and anxiolytic activity
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Czopek, Anna, Byrtus, Hanna, Kołaczkowski, Marcin, Pawłowski, Maciej, Dybała, Małgorzata, Nowak, Gabriel, Tatarczyńska, Ewa, Wesołowska, Anna, and Chojnacka-Wójcik, Ewa
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- 2010
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190. GABAergic dysfunction in mGlu7 receptor-deficient mice as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 kDa and increased reelin proteins in the hippocampus
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Wierońska, Joanna M., Brański, P., Siwek, A., Dybala, M., Nowak, G., and Pilc, A.
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- 2010
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191. Managing Water Stored for the Environment During Drought
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Null, Sarah, Mount, Jeffrey, Gray, Brian, Dettinger, Michael, Dybala, Kristen, Sencan, Gokce, Sturrock, Anna, Thompson, Barton, Zeff, Harrison, and Public Policy Institute of California
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Central Valley Project ,Water Resource Management ,freshwater ecosystem health ,water storage ,State Water Project ,drought - Abstract
Storing water in reservoirs is important for maintaining freshwater ecosystem health and protecting native species. Stored water also is essential for adapting to the changing climate, especially warming and drought intensification. Yet, reservoir operators often treat environmental objectives as a constraint, rather than as a priority akin to water deliveries for cities and farms. Reservoir management becomes especially challenging during severe droughts when surface water supplies are scarce, and urban and agricultural demands conflict with water supplies needed to maintain healthy waterways and wetlands. In times of drought, most freshwater ecosystems suffer. This blog post examines 2021 water year actions by the federal Central Valley Project (CVP) and the State Water Project (SWP), which sought to maximize water deliveries while meeting environmental regulatory standards in a severe drought. Based on this experience, we offer recommendations to better protect the environment if California is faced with dry conditions in 2022 or beyond.
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- 2021
192. Lymphomatoid drug reaction developed after BNT162b2 (Comirnaty) COVID-19 vaccine manifesting as pityriasis lichenoides et varioliformis acuta-like eruption
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G Soda, Patrizia Maddalena, Teresa Grieco, V. Gomes, Alvise Sernicola, A Dybala, P Fino, E Del Duca, F Adotti, and R. Muharremi
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medicine.medical_specialty ,COVID-19 Vaccines ,Coronavirus disease 2019 (COVID-19) ,business.industry ,Skin rashes ,SARS-CoV-2 ,Authorization ,COVID-19 ,Dermatology ,Pityriasis lichenoides et varioliformis acuta ,medicine.disease ,Pityriasis Lichenoides ,Vaccination ,Clinical trial ,Infectious Diseases ,Pharmaceutical Preparations ,pityriasis lichenoides ,varioliformis acuta-like eruption ,pandemic ,vaccination campaign ,skin rashes ,Pandemic ,Medicine ,Humans ,Drug reaction ,business ,BNT162 Vaccine - Abstract
The current global healthcare response to the COVID-19 pandemic is focused on a widespread vaccination campaign, which started with the authorization of Pfizer/BioNTech and Moderna mRNA COVID-19 vaccines in December 2020. Local injection site reactions have been described during the clinical trials of both the abovementioned mRNA vaccines; skin rashes were additionally reported in the trial of Moderna. Despite this, cutaneous adverse reactions to the vaccines and their timing remain to date poorly characterized (1,2).
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- 2021
193. Magnetism in Au-Supported Planar Silicene
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Andrzej Bobyk, Agnieszka Stępniak-Dybala, Ryszard Zdyb, and Mariusz Krawiec
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Materials science ,Dopant ,Condensed matter physics ,Magnetism ,Silicene ,General Chemical Engineering ,Substrate (electronics) ,2D materials ,Fe ,Article ,Co ,Condensed Matter::Materials Science ,Chemistry ,Ferromagnetism ,magnetism ,Ab initio ,Antiferromagnetism ,General Materials Science ,Density functional theory ,Ground state ,silicene ,QD1-999 - Abstract
The adsorption and substitution of transition metal atoms (Fe and Co) on Au-supported planar silicene have been studied by means of first-principles density functional theory calculations. The structural, energetic and magnetic properties have been analyzed. Both dopants favor the same atomic configurations with rather strong binding energies and noticeable charge transfer. The adsorption of Fe and Co atoms do not alter the magnetic properties of Au-supported planar silicene, unless a full layer of adsorbate is completed. In the case of substituted system only Fe is able to produce magnetic ground state. The Fe-doped Au-supported planar silicene is a ferromagnetic structure with local antiferromagnetic ordering. The present study is the very first and promising attempt towards ferromagnetic epitaxial planar silicene and points to the importance of the substrate in structural and magnetic properties of silicene.
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- 2021
194. Revealing the unknown aspects of initial steps of prenylated flavin mononucleotide biosynthesis – the role of Lys129 in PaUbiX
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Zaczek, Szymon, primary and Dybala-Defratyka, Agnieszka, additional
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- 2021
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195. Exome Sequencing Reveals Novel Variants and Expands the Genetic Landscape for Congenital Microcephaly
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Dawidziuk, Mateusz, primary, Gambin, Tomasz, additional, Bukowska-Olech, Ewelina, additional, Antczak-Marach, Dorota, additional, Badura-Stronka, Magdalena, additional, Buda, Piotr, additional, Budzynska, Edyta, additional, Castaneda, Jennifer, additional, Chilarska, Tatiana, additional, Czyzyk, Elzbieta, additional, Eckersdorf-Mastalerz, Anna, additional, Fijak-Moskal, Jolanta, additional, Gieruszczak-Bialek, Dorota, additional, Glodek-Brzozowska, Ewelina, additional, Goszczanska-Ciuchta, Alicja, additional, Grzeszykowska-Podymniak, Malgorzata, additional, Gurda, Barbara, additional, Jakubiuk-Tomaszuk, Anna, additional, Jamroz, Ewa, additional, Janeczko, Magdalena, additional, Jedlińska-Pijanowska, Dominika, additional, Jurek, Marta, additional, Karolewska, Dagmara, additional, Kazmierczak, Adela, additional, Kleist, Teresa, additional, Kochanowska, Iwona, additional, Krajewska-Walasek, Malgorzata, additional, Kufel, Katarzyna, additional, Kutkowska-Kaźmierczak, Anna, additional, Lipiec, Agata, additional, Maksym-Gasiorek, Dorota, additional, Materna-Kiryluk, Anna, additional, Mazurkiewicz, Hanna, additional, Milewski, Michał, additional, Pavina-Guglas, Tatsiana, additional, Pietrzyk, Aleksandra, additional, Posmyk, Renata, additional, Pyrkosz, Antoni, additional, Rudzka-Dybala, Mariola, additional, Slezak, Ryszard, additional, Wisniewska, Marzena, additional, Zalewska-Miszkurka, Zofia, additional, Szczepanik, Elzbieta, additional, Obersztyn, Ewa, additional, Bekiesinska-Figatowska, Monika, additional, Gawlinski, Pawel, additional, and Wiszniewski, Wojciech, additional
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- 2021
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196. Isotope Effects on the Vaporization of Organic Compounds from an Aqueous Solution–Insight from Experiment and Computations
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Rostkowski, Michał, primary, Schürner, Heide K. V., additional, Sowińska, Agata, additional, Vasquez, Luis, additional, Przydacz, Martyna, additional, Elsner, Martin, additional, and Dybala-Defratyka, Agnieszka, additional
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- 2021
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197. Hidden spin-polarized bands in semiconducting 2H-MoTe2
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J. Kopaczek, P. Scharoch, R. Oliva, Robert Kudrawiec, F. Dybala, and Tomasz Woźniak
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010302 applied physics ,Materials science ,spin–valley locking ,Condensed matter physics ,transition metal dichalcogenides ,photoreflectance ,02 engineering and technology ,021001 nanoscience & nanotechnology ,01 natural sciences ,law.invention ,law ,0103 physical sciences ,lcsh:TA401-492 ,General Materials Science ,Density functional theory ,lcsh:Materials of engineering and construction. Mechanics of materials ,Hydrostatic equilibrium ,two-dimensional materials ,0210 nano-technology ,Electronic band structure ,density functional theory ,Spin-½ - Abstract
We present experimental and theoretical studies of the electronic band structure of 2H-MoTe2 at high hydrostatic pressures. Photoreflectance measurements allowed the determination of the pressure coefficient of the direct transitions A and B, which are 2.40(3) and −3.42(18) meV/kbar, respectively. We attribute the sign difference to a strong splitting of the conduction bands with increasing pressure and the presence of hidden spin-polarized states in bulk MoTe2. These results provide direct experimental evidence that the spin–valley locking effect takes place in centrosymmetric transition metal dichalcogenides.
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- 2020
198. Shifting Effects of Ocean Conditions on Survival and Breeding Probability of a Long-Lived Seabird.
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Annie E Schmidt, Kristen E Dybala, Louis W Botsford, John M Eadie, Russell W Bradley, and Jaime Jahncke
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Medicine ,Science - Abstract
With a rapidly changing climate, there is an increasing need to predict how species will respond to changes in the physical environment. One approach is to use historic data to estimate the past influence of environmental variation on important demographic parameters and then use these relationships to project the abundance of a population or species under future climate scenarios. However, as novel climate conditions emerge, novel species responses may also appear. In some systems, environmental conditions beyond the range of those observed during the course of most long-term ecological studies are already evident. Yet little attention has been given to how these novel conditions may be influencing previously established environment-species relationships. Here, we model the relationships between ocean conditions and the demography of a long-lived seabird, Brandt's cormorant (Phalacrocorax penicillatusI), in central California and show that these relationships have changed in recent years. Beginning in 2007/2008, the response of Brandt's cormorant, an upper trophic level predator, to ocean conditions shifted, resulting in lower than predicted survival and breeding probability. Survival was generally less variable than breeding probability and was initially best predicted by the basin-scale forcing of the El Niño Southern Oscillation rather than local ocean conditions. The shifting response of Brandt's cormorant to ocean conditions may be just a proximate indication of altered dynamics in the food web and that important forage fish are not responding to the physical ocean environment as expected. These changing relationships have important implications for our ability to project the effects of future climate change for species and communities.
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- 2015
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199. Disparity in Adiposity among Adults with Normal Body Mass Index and Waist-to-Height Ratio
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Matthew J. Brady, Manami Hara, and Michael P. Dybala
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0301 basic medicine ,National Health and Nutrition Examination Survey ,02 engineering and technology ,Article ,Fat mass ,03 medical and health sciences ,Obesity medicine ,medicine ,Obesity Medicine ,lcsh:Science ,Nutrition ,2. Zero hunger ,Waist-to-height ratio ,Multidisciplinary ,business.industry ,nutritional and metabolic diseases ,021001 nanoscience & nanotechnology ,medicine.disease ,Control subjects ,Obesity ,3. Good health ,030104 developmental biology ,Normal body mass index ,lcsh:Q ,Public Health ,0210 nano-technology ,business ,Body mass index ,Demography - Abstract
Summary Body mass index (BMI) is commonly used to define obesity. However, concerns about its accuracy in predicting adiposity have been raised. The feasibility of using BMI as well as waist-height ratio (WHtR) in assessing adiposity was examined in relation to a more direct measurement of percent body fat (%BF). We analyzed the relation between dual-energy X-ray absorptiometry (DXA)-measured fat mass and BMI and WHtR using the US 1999–2004 National Health and Nutrition Examination Survey (NHANES) data. A considerable proportion of subjects in the healthy BMI range 20–25 were found to have excess adiposity, including 33.1% of males and 51.9% of females. The use of WHtR also supports the notion of normal-weight central obesity (NWCO), which increases with age. These findings have important implications not only for clinical practice but also for many comparative studies where control subjects are usually selected based on age, sex, and BMI., Graphical Abstract, Highlights • BMI > 30 reliably defines obesity regardless of age and sex • People with BMI of 20–25 and WHtR < 0.5 showed age-dependent hidden obesity • Subjects with excess body fat and BMI range of 20–25 showed increased WHtR with increased age • The present study supports the new notion of normal-weight central obesity, Public Health; Nutrition; Obesity Medicine
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- 2019
200. Simulation of Influence of Transverse Wheel-Set Movement on Torsion Oscillations
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Vojtěch Dybala and Bohumil Šulc
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Physics ,Torsion (mechanics) ,Mathematical physics - Abstract
S rostoucim významem kolejove dopravy rostou take naroky na ekonomiku a funkcnost jejiho provozu. Ty jsou ovlivňovany řadou faktorů, jejichž identifikace, přime zjisťovani a dopad je v realnem provozu velmi obtižne měřit nebo dlouhodobě sledovat. Pocitacova simulace a kladkový stav jsou vhodnými prostředky, kterými lze rozpoznat miru vlivu fyzikalnich omezeni ve spojeni s navrhovanou konstrukci vozidla a s předpokladanými okolnimi podminkami provozu vse vyjasnit před uvedenim vozidla do vlastniho provozu. Proto byl v ramci SGS (studentska grantova soutěž) a doktorských studijnich programů sestaven, použivan a rozvijen model v Simulinku zaměřený na oblast výzkumu torzni dynamiky hnaných naprav a vlivu adheznich podminek. V minulosti sloužil ke zkoumani torzniho kmitani buzeneho změnami přenosu krouticiho momentu. V tomto clanku se zaměřujeme na jiný zdroj asynchronni obvodovou rychlost kol dvojkoli. To je dano kuželovitosti kol kolejových vozidel. Bude ukazano, jak změna průměru kontaktni kružnice ovlivňuje torzni zatiženi osy dvojkoli a druh zatiženi.
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- 2019
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