1,923 results on '"DePinho, Ronald A."'
Search Results
152. Adiponectin Regulates Bone Mass via Opposite Central and Peripheral Mechanisms through FoxO1
153. Murine dendritic cell rapamycin-resistant and rictor-independent mTOR controls IL-10, B7-H1, and regulatory T-cell induction
154. QnAs with Ronald DePinho
155. Neutralization of terminal differentiation in gliomagenesis
156. Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer
157. Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer
158. Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer
159. Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240
160. IRS2 Signaling in LepR-b Neurons Suppresses FoxO1 to Control Energy Balance Independently of Leptin Action
161. FoxOs Integrate Pleiotropic Actions of Insulin in Vascular Endothelium to Protect Mice from Atherosclerosis
162. Abstract 3208: Angiogenesis inhibitors strongly synergize with therapeutics targeting tumor metabolism
163. ATR-mediated CD47 and PD-L1 up-regulation restricts radiotherapy-induced immune priming and abscopal responses in colorectal cancer
164. STOPTRAFFIC-1: A phase I/II trial of SX-682 in combination with nivolumab for refractory RAS-mutated microsatellite stable (MSS) metastatic colorectal cancer (mCRC).
165. Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma
166. Synthetic Essentiality of Tryptophan 2,3-Dioxygenase 2 in APC-Mutated Colorectal Cancer
167. The Role for ink4a in Melanoma Pathogenesis : One Gene, Two Products, Multiple Pathways
168. Mig-6 controls EGFR trafficking and suppresses gliomagenesis
169. Dissecting Genetic Requirements of Human Breast Tumorigenesis in a Tissue Transgenic Model of Human Breast Cancer in Mice
170. mTORC1-Dependent and -Independent Regulation of Stem Cell Renewal, Differentiation, and Mobilization
171. Genomic Alterations Link Rho Family of GTPases to the Highly Invasive Phenotype of Pancreas Cancer
172. Bcl2L12-Mediated Inhibition of Effector Caspase-3 and Caspase-7 via Distinct Mechanisms in Glioblastoma
173. Specific Requirement of the Chromatin Modifier mSin3B in Cell Cycle Exit and Cellular Differentiation
174. Lung Cancer Signatures in Plasma Based on Proteome Profiling of Mouse Tumor Models
175. Proinvasion Metastasis Drivers in Early-Stage Melanoma Are Oncogenes
176. Coactivation of Receptor Tyrosine Kinases Affects the Response of Tumor Cells to Targeted Therapies
177. ARF Functions as a Melanoma Tumor Suppressor by Inducing p53-Independent Senescence
178. Ink4a/Arf Tumor Suppressor Does Not Modulate the Degenerative Conditions or Tumor Spectrum of the Telomerase-Deficient Mouse
179. Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer
180. Histone demethylase KDM5D drives sex-specific differences in colorectal cancer
181. Both $p16^{Ink4a}$ and the $p19^{Arf}-p53$ Pathway Constrain Progression of Pancreatic Adenocarcinoma in the Mouse
182. Mouse Model for Noninvasive Imaging of HIF Prolyl Hydroxylase Activity: Assessment of an Oral Agent That Stimulates Erythropoietin Production
183. Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function
184. FoxO1 Is a Positive Regulator of Bone Formation by Favoring Protein Synthesis and Resistance to Oxidative Stress in Osteoblasts
185. FoxO-Mediated Defense against Oxidative Stress in Osteoblasts Is Indispensable for Skeletal Homeostasis in Mice
186. FoxOs Enforce a Progression Checkpoint to Constrain mTORC1-Activated Renal Tumorigenesis
187. PLAGL2 Regulates Wnt Signaling to Impede Differentiation in Neural Stem Cells and Gliomas
188. Telomerase reverse transcriptase preserves neuron survival and cognition in Alzheimer’s disease models
189. Lipid-loaded tumor-associated macrophages sustain tumor growth and invasiveness in prostate cancer
190. 592 ATR-mediated CD47 and PD-L1 upregulation restricts radiotherapy-induced immune priming and abscopal responses in colorectal cancer
191. Drivers of transcriptional variance in human intestinal epithelial organoids
192. Context-Dependent Transformation of Adult Pancreatic Cells by Oncogenic K-Ras
193. The Y of cancer sex differences.
194. Contrasting Roles for Myc and Mad Proteins in Cellular Growth and Differentiation
195. Structure and Expression of the Murine N-myc Gene
196. Suppression of Myc, but not E1a, Transformation Activity by Max-Associated Proteins, Mad and Mxi1
197. The Glucocorticoid Hormone Signal Transduction Pathway in Mice Homozygous for Chromosomal Deletions Causing Failure of Cell Type-Specific Inducible Gene Expression
198. Inhibition of Ras-Induced Proliferation and Cellular Transformation by p16$^{INK4}$
199. Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
200. Endothelial FoxO1 is an intrinsic regulator of thrombospondin 1 expression that restrains angiogenesis in ischemic muscle
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