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151. Topological supramolecular network enabled high-conductivity, stretchable organic bioelectronics

Author

Jiang, Yuanwen, primary, Zhang, Zhitao, additional, Wang, Yi-Xuan, additional, Li, Deling, additional, Coen, Charles-Théophile, additional, Hwaun, Ernie, additional, Chen, Gan, additional, Wu, Hung-Chin, additional, Zhong, Donglai, additional, Niu, Simiao, additional, Wang, Weichen, additional, Saberi, Aref, additional, Lai, Jian-Cheng, additional, Wu, Yilei, additional, Wang, Yang, additional, Trotsyuk, Artem A., additional, Loh, Kang Yong, additional, Shih, Chien-Chung, additional, Xu, Wenhui, additional, Liang, Kui, additional, Zhang, Kailiang, additional, Bai, Yihong, additional, Gurusankar, Gurupranav, additional, Hu, Wenping, additional, Jia, Wang, additional, Cheng, Zhen, additional, Dauskardt, Reinhold H., additional, Gurtner, Geoffrey C., additional, Tok, Jeffrey B.-H., additional, Deisseroth, Karl, additional, Soltesz, Ivan, additional, and Bao, Zhenan, additional

Published
2022
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154. Topological supramolecular network enabled highly conductive and stretchable organic bioelectronics

Author

Jiang, Yuanwen, primary, Zhang, Zhitao, additional, Wang, Yi-Xuan, additional, Li, Deling, additional, Coen, Charles-Théophile, additional, Hwaun, Ernie, additional, Chen, Gan, additional, Wu, Hung-Chin, additional, Zhong, Donglai, additional, Niu, Simiao, additional, Wang, Weichen, additional, Saberi, Aref, additional, Lai, Jian-Cheng, additional, Wang, Yang, additional, Trotsyuk, Artem A., additional, Loh, Kang Yong, additional, Shih, Chien-Chung, additional, Xu, Wenhui, additional, Liang, Kui, additional, Zhang, Kailiang, additional, Hu, Wenping, additional, Jia, Wang, additional, Cheng, Zhen, additional, Dauskardt, Reinhold H., additional, Gurtner, Geoffrey C., additional, Tok, Jeffery B.-H., additional, Deisseroth, Karl, additional, Soltesz, Ivan, additional, and Bao, Zhenan, additional

Published
2022
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159. Do hotel business benefit from increased tourist accessibility? Evidence from China’s high-speed railway program

Author

Chen Gan, Yukun Hu, and Taotao Deng

Subjects
Tourism, Leisure and Hospitality Management, 0502 economics and business, 05 social sciences, Geography, Planning and Development, Key (cryptography), 050211 marketing, Business, Marketing, China, 050212 sport, leisure & tourism, Tourism
Abstract

The operation of high-speed railway (HSR) always plays a key role in promoting tourism development of city by improving transportation accessibility and facilitating tourists’ travel. Based on the panel data of 50 major tourist cities in China from 2010 to 2017, this article uses a Tobit model to explore the impact of HSR service on hotel performance that is embodied in occupancy rate. The results show that with other factors unchanged, the cities with a high-frequency HSR service system or hub HSR station tend to have higher hotel occupancy rate. Moreover, the hotel occupancy rate of cities with a suburb HSR station is lower than that of other HSR-served cities. After classifying hotels into luxury and budget groups, this article finds that HSR train frequency and station grade still show positive effects on both luxury and budget hotels. However, in cities with suburb HSR stations, budget hotels tend to have lower occupancy rates, while occupancy rate for luxury hotels shows no significant difference.

Published
2020

160. Downregulation of TNFRSF19 and RAB43 by a novel miRNA, miR-HCC3, promotes proliferation and epithelial–mesenchymal transition in hepatocellular carcinoma cells

Author

Jian Chen Gan, Ya Nan Zhu, Yi Zhang, Rui Gao, Ping Lv, Hua Tang, Li Ming Guo, Jun Yi Ma, and Shengping Li

Subjects
0301 basic medicine, Carcinoma, Hepatocellular, Epithelial-Mesenchymal Transition, Biophysics, Down-Regulation, Mice, Nude, medicine.disease_cause, Biochemistry, Receptors, Tumor Necrosis Factor, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Cell Line, Tumor, microRNA, medicine, Animals, Humans, Epithelial–mesenchymal transition, Molecular Biology, Mice, Inbred BALB C, Gene knockdown, Cell growth, Chemistry, Liver Neoplasms, Hep G2 Cells, Cell Biology, medicine.disease, digestive system diseases, Transmembrane protein, Gene Expression Regulation, Neoplastic, 030104 developmental biology, rab GTP-Binding Proteins, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Cancer research, Female, Carcinogenesis
Abstract

Tumor necrosis factor receptor superfamily 19 (TNFRSF19) is a transmembrane protein involved in tumorigenesis. RAB43 is a small molecule GTP-binding protein contributing to the occurrence and development of tumors. However, TNFRSF19/RAB43 dysregulation and their role in hepatocellular carcinoma cells are unknown. Herein, we found that TNFRSF19 and RAB43 were downregulated in hepatocellular carcinoma tissues. TNFRSF19/RAB43 overexpression suppressed, whereas TNFRSF19/RAB43 knockdown promoted cell proliferation and epithelial–mesenchymal transition (EMT) of hepatocellular carcinoma cells. Previously, using deep sequencing technology, a new miRNA, miR-HCC3, was identified and found to suppress the expression of TNFRSF19 and RAB43 by binding to their 3′untranslated regions (3′UTRs) directly. miR-HCC3 was upregulated in hepatocellular carcinoma (HCC) tissues compared with adjacent noncancerous tissues and promoted proliferation and epithelial-mesenchymal transition in HCC cells. Furthermore, TNFRSF19/RAB43 suppressed but miR-HCC3 promoted tumor growth in vivo. Collectively, our results indicated that downregulation of TNFRSF19 and RAB43 by miR-HCC3 contributes to oncogenic activities in HCC, which sheds light on tumorigenesis and might provide potential therapeutic targets for HCC.

Published
2020

161. Consumers’ engagement with corporate social responsibility (CSR) communication in social media: Evidence from China and the United States

Author

Shu-Chuan Chu, Hsuan-Ting Chen, and Chen Gan

Subjects
Marketing, Electronic word of mouth, Peer communication, 0502 economics and business, 05 social sciences, Opinion leadership, Corporate social responsibility, 050211 marketing, Advertising, Social media, China, Psychology, 050203 business & management
Abstract

This study investigates cross-cultural differences between Chinese and American consumers in the relationships of electronic word-of-mouth (eWOM) intentions and consumers’ engagement with CSR communication through social media with three antecedents: (1) attitude toward CSR in social media, (2) peer communication about CSR activities, and (3) opinion leadership characteristics. An online survey was conducted with samples of social media users in China and the U.S. Results from the multiple-group analysis show that the degree of impact of the three antecedents varies significantly between consumers in China and the U.S. Specifically, the influence of attitudes toward CSR in social media on consumers’ engagement with CSR communication in social media is stronger for the Chinese participants than for the U.S. participants. In addition, peer communication and opinion leadership characteristics have significantly stronger effects on consumers’ engagement with CSR communication via social media for the Chinese participants than for the U.S. participants.

Published
2020

162. Bone Metastasis of Breast Cancer: Molecular Mechanisms and Therapeutic Strategies

Author

Lulian Pang, Chen Gan, Jian Xu, Yingxue Jia, Jiaying Chai, Runze Huang, Anlong Li, Han Ge, Sheng Yu, and Huaidong Cheng

Subjects
Cancer Research, Oncology
Abstract

Bone metastasis is a common complication of many types of advanced cancer, including breast cancer. Bone metastasis may cause severe pain, fractures, and hypercalcemia, rendering clinical management challenging and substantially reducing the quality of life and overall survival (OS) time of breast cancer patients. Studies have revealed that bone metastasis is related to interactions between tumor cells and the bone microenvironment, and involves complex molecular biological mechanisms, including colonization, osteolytic destruction, and an immunosuppressive bone microenvironment. Agents inhibiting bone metastasis (such as bisphosphate and denosumab) alleviate bone destruction and improve the quality of life of breast cancer patients with bone metastasis. However, the prognosis of these patients remains poor, and the specific biological mechanism of bone metastasis is incompletely understood. Additional basic and clinical studies are urgently needed, to further explore the mechanism of bone metastasis and develop new therapeutic drugs. This review presents a summary of the molecular mechanisms and therapeutic strategies of bone metastasis of breast cancer, aiming to improve the quality of life and prognosis of breast cancer patients and provide a reference for future research directions.

Published
2022

163. Correlation of dielectric dispersion with distributed Curie temperature in relaxor ferroelectrics.

Author

Chen, Yong, Liu, Kang Hui, Luo, Qian, Mei, Ming, Chen, Gan Lin, Pan, Rui Kun, Qi, Ya Jun, and Cao, Wan Qiang

Subjects
DIELECTRICS, FERROELECTRICITY, CURIE temperature, PHASE transitions, MEAN field theory
Abstract

The fascinating dielectric property of relaxor ferroelectrics is investigated on the basis of phase-transition dynamics within the mean-field theory. With a power-law distribution of the Curie temperature for the second order phase transition ferroelectrics, the complex dielectric permittivity is derived. The result shows that the modified Curie–Weiss relation in the paraelectric phase follows the power-law distribution directly. The significant conclusion is that the "rediscovered" distributed Curie temperature can describe the universal dielectric dispersion for both real part and imaginary part of dielectric permittivity with temperature and frequency in relaxor ferroelectrics, and it conforms well to experimental results. [ABSTRACT FROM AUTHOR]

Published
2019
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166. Late Quaternary active faulting on the inherited Baoertu basement fault within the eastern Tian Shan orogenic belt: Implications for regional tectonic deformation and slip partitioning, NW China

Author

Wu, Chuanyong, primary, Ren, Guangxue, additional, Wang, Siyu, additional, Yang, Xue, additional, Chen, Gan, additional, Duan, Lei, additional, Zhang, Zhuqi, additional, Zheng, Wenjun, additional, Li, Chuanyou, additional, Ren, Zhikun, additional, Lei, Qiyun, additional, and Zhang, Dongli, additional

Published
2021
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169. Efficacy and Safety of Ejiao (Asini Corii Colla) in Women With Blood Deficient Symptoms: A Randomized, Double-Blind, and Placebo-Controlled Clinical Trial

Author

Zhang, Li, primary, Xu, Zhongju, additional, Jiang, Tao, additional, Zhang, Jialu, additional, Huang, Pinxian, additional, Tan, Jiaqi, additional, Chen, Gan, additional, Yuan, Man, additional, Li, Zhuo, additional, Liu, Haibin, additional, Gao, Dengfeng, additional, Xiao, Lianbo, additional, Feng, Hui, additional, Xu, Jiatuo, additional, and Xu, Hongxi, additional

Published
2021
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170. Nonrigid Bookshelf Kinematics of Northeastern Tibet: Constrains from Fault Slip Rates around the Qinghai Lake and Chaka-Gonghe Basins

Author

Liu Jinrui, Songjian Ao, GE Wei-peng, Chen Gan, Ai Ming, Zhang Yipeng, Zheng Wenjun, Bi Haiyun, Huang Rong, and Zhang Dongli

Subjects
Geology, Kinematics, Fault slip, Qinghai lake, Seismology
Abstract

The Elashan fault (ELSF) and Qinghainanshan fault (QHNF), two major faults developed around the Qinghai Lake and Chaka-Gonghe basins, are of great importance for investigating the deformation model of the internal northeastern Tibetan Plateau. However, their late Pleistocene slip rates remain poorly constrained. In this study, we combine high-resolution topography acquired from unmanned aerial vehicles (UAV) and geomorphological dating to calculate the slip rates of the two faults. We visited the central ELSF and western QHNF and measured displaced terraces and stream channels. We collected 10Be samples on the surface of terraces to constrain the abandonment ages. The dextral slip rate of the central segment of the Elashan fault is estimated to be 2.6±1.2 mm/yr. The uplift rates since the late Pleistocene of the Elashan and Qinghainanshan faults are 0.4±0.04 mm/yr and 0.2±0.03 mm/yr, respectively. Comparing the geological rates with the newly published global positioning system (GPS) rates, we find that the slip rates of the major strike-slip faults around the Qinghai Lake and Chaka-Gonghe basins are approximately consistent from the late Pleistocene to the present day. The overall NE shortening rates by summing up the geological slip rates on major faults between the East Kunlun and Haiyuan faults are ~3.4 mm/yr, smaller than the geodetic shortening rates (~4.9 to 6.4 mm/yr), indicating that distributed deformation plays an important role in accommodating the regional deformation. By analyzing the geometrical and kinematic characteristics of the major faults surrounding the basins, we suggest that the kinematic deformation of the internal northeastern Tibet is a nonrigid bookshelf model that consists of counterclockwise rotation (~0.8° Myr-1) and distributed thrusting.

Published
2021

171. Predicting Neurostimulation Responsiveness with Dynamic Brain Network Measures

Author

Lizhuang Yang, Hongzhi Wang, Chen Gan, Hai Li, Yan-Fei Zhou, Xiao Fu, Zong-Tao Hu, Wenjuan Wang, and Jin-Wei Lang

Subjects
Brain network, Dynamic network analysis, medicine.anatomical_structure, Transcranial direct-current stimulation, Computer science, medicine.medical_treatment, Temporoparietal junction, medicine, Neuroscience, Neurostimulation, Neurocognitive, Default mode network, Dynamic functional connectivity
Abstract

Transcranial direct current stimulation (tDCS) shows great promise in enhancing neurocognitive abilities. However, the neurostimulation responsiveness varied hugely. Our previous work demonstrates that people receiving tDCS stimulation over Temporoparietal Junction (TPJ) fall into two heterogeneous groups: the positive responders who benefit and the negative responders who hurt from tDCS. The present study investigated whether dynamic brain network properties of resting-state fMRI could predict the pattern. We calculated each subsystem of the default mode network’s dynamic attributes using the multilayer community detection algorithm. Results indicated that the recruitment indexes were significantly different in bilateral aMPFC, PCC, Rsp, and PHC regions between positive responders and negative responders. Our results also confirm the advantages of the dynamic network measures over the static network measures. The study provides a feasible protocol in establishing the pre-stimulation screening procedure using resting-state fMRI.

Published
2021

175. Correction to “A Design Strategy for Intrinsically Stretchable High-Performance Polymer Semiconductors: Incorporating Conjugated Rigid Fused-Rings with Bulky Side Groups”

Author

Liu, Deyu, primary, Mun, Jaewan, additional, Chen, Gan, additional, Schuster, Nathaniel J., additional, Wang, Weichen, additional, Zheng, Yu, additional, Nikzad, Shayla, additional, Lai, Jian-Cheng, additional, Wu, Yilei, additional, Zhong, Donglai, additional, Lin, Yangju, additional, Lei, Yusheng, additional, Chen, Yuelang, additional, Park, Jeong-Il, additional, Gam, Sangah, additional, Chung, Jong Won, additional, Yun, Youngjun, additional, Tok, Jeffrey B.-H., additional, and Bao, Zhenan, additional

Published
2021
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176. Foliar application of silicon boosts growth, photosynthetic leaf gas exchange, antioxidative response and resistance to limited water irrigation in sugarcane (Saccharum officinarum L.)

Author

Verma, Krishan K., primary, Song, Xiu-Peng, additional, Zeng, Yuan, additional, Guo, Dao-Jun, additional, Singh, Munna, additional, Rajput, Vishnu D., additional, Malviya, Mukesh Kumar, additional, Wei, Kai-Jun, additional, Sharma, Anjney, additional, Li, Dong-Ping, additional, Chen, Gan-Lin, additional, and Li, Yang-Rui, additional

Published
2021
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179. A Design Strategy for Intrinsically Stretchable High-Performance Polymer Semiconductors: Incorporating Conjugated Rigid Fused-Rings with Bulky Side Groups

Author

Liu, Deyu, primary, Mun, Jaewan, additional, Chen, Gan, additional, Schuster, Nathaniel J., additional, Wang, Weichen, additional, Zheng, Yu, additional, Nikzad, Shayla, additional, Lai, Jian-Cheng, additional, Wu, Yilei, additional, Zhong, Donglai, additional, Lin, Yangju, additional, Lei, Yusheng, additional, Chen, Yuelang, additional, Gam, Sangah, additional, Chung, Jong Won, additional, Yun, Youngjun, additional, Tok, Jeffrey B.-H., additional, and Bao, Zhenan, additional

Published
2021
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180. Enhancing electrochemical energy storage capacity and rate performance of the anode with a 3D interconnected carbon tube-NiO-SnO2composite scaffold

Author

Zhang, Shiping, Han, Fangming, Pan, Qijun, Lin, Dou, Chen, Gan, Mu, Xiaowei, Zhu, Xiaoguang, Shao, Cheng, Wu, Nianqiang, and Meng, Guowen

Abstract

Tin dioxide (SnO2) possesses great potential as an anode material for lithium-ion batteries (LIBs) owing to its high theoretical specific capacity. However, the irreversible conversion of Sn to SnO2and enormous volume variation during the charge/discharge process limit the battery energy storage performance. In this study, ultrafine NiO and SnO2nanoparticles (NPs) decorated on a three-dimensionally (3D) interconnected and structurally integrated carbon tube (CT) scaffold (NiO/SnO2-NPs@3D-CT) is developed as an anode, eliminating any inactive component in the electrode. The NiO not only contributes to the capacity but also undergoes reduction to Ni during the lithiation process, which catalyzes Li2O decomposition and facilitates the reversible conversion of Sn to SnO2. Additionally, the open space of the 3D scaffold can host a large number of NiO/SnO2NPs and results in a short diffusion distance of Li+between the electrolyte and the Li+host. The interconnected 3D-CT network serves as a fast electron transport channel. Consequently, the unique structure endows the anode with high Li-ion storage capacity (928.5 mA h g−1at a current density of 1 A g−1after 200 cycles) and superior high-rate performance; for instance, a reversible capacity of 633.5 mA h g−1can be achieved even at a current density of 4 A g−1. We believe that the unique, integrated 3D structure holds great promise as an anode for LIBs and that its applications can be further extended to other fields.

Published
2023
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181. Effects of electrode materials on solution-processed polyvinylidene fluoride-based piezoelectric nanogenerators: Do they matter?

Author

Yi Sheng Ng, Zhi Yong Yau, Poh Choon Ooi, Rahmat Zaki Auliya, Thiresamary Kurian, Mengying Xie, Sin Tee Tan, Yew Hoong Wong, Muhammad Aniq Shazni Mohammad Haniff, Wee Chen Gan, Chun Hui Tan, Sameer Al-Bati, Khatatbeh Ibtehaj, Azrul Azlan Hamzah, and Chang Fu Dee

Subjects
Materials Chemistry, Electrical and Electronic Engineering, Condensed Matter Physics, Electronic, Optical and Magnetic Materials
Published
2022

189. Late Quaternary Slip Behavior of the Jinqianghe Fault in the Middle Qilian–Haiyuan Fault Zone, Northeastern Tibetan Plateau.

Author

LIANG, Shumin, ZHENG, Wenjun, CHEN, Gan, ZHANG, Peizhen, ZHANG, Dongli, BI, Haiyun, YANG, Xue, ZHANG, Yipeng, DUAN, Lei, and LU, Bentian

Subjects
FAULT zones, SURFACE fault ruptures, DIGITAL photogrammetry, AERIAL photogrammetry, DIGITAL elevation models, RADIOCARBON dating
Abstract

The Qilian–Haiyuan fault zone in the northeastern Tibetan Plateau has been the source of strong earthquakes in the region. In its middle segment, the Jinqianghe fault is an important active fault within the Tianzhu seismic gap; however, little is known about its slip behavior. To present a new horizontal displacement distribution along this fault, we used WorldView‐2 stereo pairs and unmanned aerial vehicle‐based photogrammetry to construct digital elevation models to obtain a detailed tectono‐geomorphic interpretation and geomorphic offsets. The offset marker measurements yielded 135 geomorphic displacements and 8 offset clusters. Radiocarbon dating was used to establish the regional age sequence of the geomorphic units in offset fluvial terraces at four study sites. The displacements and ages linked the offset clusters with the geomorphic unit sequence; the Holocene strike‐slip rate of the Jinqianghe fault was estimated to 4.8–5.6 mm/a at ∼4–12 ka and 2.9–4.7 mm/a from ∼4 ka. Three recent earthquakes (with a recurrence interval of ∼1000 years) represent an active seismic period, revealing the potential seismic hazard along this fault because it has not ruptured in the last 1500 years. [ABSTRACT FROM AUTHOR]

Published
2022
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191. Carotid Artery Dissection and Ischemic Stroke Following Cervical Chiropractic Manipulation: Two Case Reports.

Author

Chen, Yimin, Mofatteh, Mohammad, Nguyen, Thanh N., Wellington, Jack, Wei, Wenlong, Liang, Wenjun, Chen, Gan, Hu, Zhaohui, Ouyang, Kexun, and Yang, Shuiquan

Subjects
CAROTID artery dissections, ISCHEMIC stroke, CLOPIDOGREL, SPINAL adjustment, PATIENT safety, TISSUE plasminogen activator, DISEASE risk factors
Abstract

Objective: Patients can be at risk of carotid artery dissection and ischemic stroke after cervical chiropractic manipulation. However, such risks are rarely reported and raising awareness can increase the safety of chiropractic manipulations. Case Report: We present two middle-aged patients with carotid artery dissection leading to ischemic stroke after receiving chiropractic manipulation in Foshan, Guangdong Province, China. Both patients had new-onset pain in their necks after receiving chiropractic manipulations. Excess physical force during chiropractic manipulation may present a risk to patients. Patient was administered with recombinant tissue plasminogen activator after radiological diagnoses. They were prescribed 100 mg and clopidogrel 75 mg daily for 3 months as dual antiplatelet therapy. There were no complications over the follow-up period. Conclusion: These cases suggest that dissection of the carotid artery can occur as the result of chiropractic manipulations. Patients should be diagnosed and treated early to achieve positive outcomes. The safety of chiropractic manipulations should be increased by raising awareness about the potential risks. [ABSTRACT FROM AUTHOR]

Published
2022
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198. Predication of Photosynthetic Leaf Gas Exchange of Sugarcane (Saccharum spp) Leaves in Response to Leaf Positions to Foliar Spray of Potassium Salt of Active Phosphorus under Limited Water Irrigation

Author

Verma, Krishan K., primary, Song, Xiu-Peng, additional, Verma, Chhedi Lal, additional, Malviya, Mukesh Kumar, additional, Guo, Dao-Jun, additional, Rajput, Vishnu D., additional, Sharma, Anjney, additional, Wei, Kai-Jun, additional, Chen, Gan-Lin, additional, Solomon, Sushil, additional, and Li, Yang-Rui, additional

Published
2021
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