20,927 results on '"Cappelli, A"'
Search Results
152. Quantum Field Theory Anomalies in Condensed Matter Physics
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Arouca, R., Cappelli, Andrea, and Hansson, T. H.
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Condensed Matter - Strongly Correlated Electrons ,Condensed Matter - Superconductivity ,High Energy Physics - Theory - Abstract
We give a pedagogical introduction to quantum anomalies, how they are calculated using various methods, and why they are important in condensed matter theory. We discuss axial, chiral, and gravitational anomalies as well as global anomalies. We illustrate the theory with examples such as quantum Hall liquids, Fermi liquids, Weyl semi-metals, topological insulators and topological superconductors. The required background is basic knowledge of quantum field theory, including fermions and gauge fields, and some familiarity with path integral and functional methods. Some knowledge of topological phases of matter is helpful, but not necessary., Comment: Lecture notes. 148 pages, 24 figures. v2: Minor typos fixed and some references added
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- 2022
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153. Search for Neutrinoless $\beta^+EC$ Decay of $^{120}$Te with CUORE
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Adams, D. Q., Alduino, C., Alfonso, K., Avignone III, F. T., Azzolini, O., Bari, G., Bellini, F., Benato, G., Beretta, M., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Camilleri, J., Caminata, A., Campani, A., Canonica, L., Cao, X. G., Capelli, C., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Celi, E., Chiesa, D., Clemenza, M., Copello, S., Cremonesi, O., Creswick, R. J., D'Addabbo, A., Dafinei, I., Del Corso, F., Dell'Oro, S., Di Domizio, S., Di Lorenzo, S., Dompè, V., Fang, D. Q., Fantini, G., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fu, S. H., Fujikawa, B. K., Ghislandi, S., Giachero, A., Gianvecchio, A., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Huang, R. G., Huang, H. Z., Johnston, J., Keppel, G., Kolomensky, Yu. G., Kowalski, R., Ligi, C., Liu, R., Ma, L., Ma, Y. G., Marini, L., Maruyama, R. H., Mayer, D., Mei, Y., Morganti, S., Napolitano, T., Nastasi, M., Nikkel, J., Nones, C., Norman, E. B., Nucciotti, A., Nutini, I., O'Donnell, T., Olmi, M., Ouellet, J. L., Pagan, S., Pagliarone, C. E., Pagnanini, L., Pallavicini, M., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Ressa, A., Rosenfeld, C., Sakai, M., Sangiorgio, S., Schmidt, B., Scielzo, N. D., Sharma, V., Singh, V., Sisti, M., Speller, D., Surukuchi, P. T., Taffarello, L., Terranova, F., Tomei, C., Vetter, K. J., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Zimmermann, S., and Zucchelli, S.
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Nuclear Experiment - Abstract
CUORE is a large scale cryogenic experiment searching for neutrinoless double beta decay ($0\nu\beta\beta$) in $^{130}$Te. The CUORE detector is made of natural tellurium, providing the possibility of rare event searches on isotopes other than $^{130}$Te. In this work we describe a search for neutrinoless positron emitting electron capture ($0\nu\beta^+EC$) decay in $^{120}$Te with a total TeO$_2$ exposure of 355.7 kg $\cdot$ yr, corresponding to 0.2405 kg $\cdot$ yr of $^{120}$Te. Albeit $0 \nu \beta\beta$ with two final state electrons represents the most promising channel, the emission of a positron and two 511-keV $\gamma$s make $0\nu\beta^+EC$ decay signature extremely clear. To fully exploit the potential offered by the detector modularity we include events with different topology and perform a simultaneous fit of five selected signal signatures. Using blinded data we extract a median exclusion sensitivity of $3.4 \cdot 10^{22}$ yr at 90% Credibility Interval (C.I.). After unblinding we find no evidence of $0\nu\beta^+EC$ signal and set a 90% C.I. Bayesian lower limit of $2.9 \cdot 10^{22}$ yr on $^{120}$Te half-life. This result improves by an order of magnitude the existing limit from the combined analysis of CUORE-0 and Cuoricino.
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- 2022
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154. Toward CUPID-1T
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Armatol, A., Augier, C., Avignone III, F. T., Azzolini, O., Balata, M., Ballen, K., Barabash, A. S., Bari, G., Barresi, A., Baudin, D., Bellini, F., Benato, G., Beretta, M., Bettelli, M., Biassoni, M., Billard, J., Boldrini, V., Branca, A., Brofferio, C., Bucci, C., Camilleri, J., Capelli, C., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Celi, E., Chang, C., Chiesa, D., Clemenza, M., Colantoni, I., Copello, S., Craft, E., Cremonesi, O., Creswick, R. J., Cruciani, A., D'Addabbo, A., D'Imperio, G., Dabagov, S., Dafinei, I., De Jesus, M., de Marcillac, P., Dell'Oro, S., Di Domizio, S., Di Lorenzo, S., Dixon, T., Dompè, V., Drobizhev, A., Dumoulin, L., Fantini, G., Faverzani, M., Ferri, E., Ferri, F., Ferroni, F., Figueroa-Feliciano, E., Foggetta, L., Formaggio, J., Franceschi, A., Fu, C., Fu, S., Fujikawa, B. K., Gallas, A., Gascon, J., Ghislandi, S., Giachero, A., Gianvecchio, A., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Grant, C., Gras, P., Guillaumon, P. V., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Helis, D., Helis, D. L., Huang, H. Z., Huang, R. G., Imbert, L., Johnston, J., Juillard, A., Karapetrov, G., Keppel, G., Khalife, H., Kobychev, V. V., Kolomensky, Yu. G., Konovalov, S. I., Kowalski, R., Langford, T., Liu, R., Liu, Y., Loaiza, P., Ma, L., Madhukuttan, M., Mancarella, F., Marini, L., Marnieros, S., Martinez, M., Maruyama, R. H., Mauri, B., Mayer, D., Mazzitelli, G., Mei, Y., Milana, S., Morganti, S., Napolitano, T., Nastasi, M., Nikkel, J., Nisi, S., Nones, C., Norman, E. B., Novosad, V., Nutini, I., O'Donnell, T., Olivieri, E., Olmi, M., Ouellet, J. L., Pagan, S., Pagliarone, C., Pagnanini, L., Pattavina, L., Pavan, M., Peng, H., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Poda, D. V., Polischuk, O. G., Ponce, I., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Ressa, A., Rizzoli, R., Rosenfeld, C., Rosier, P., Scarpaci, J., Schmidt, B., Sharma, V., Shlegel, V., Singh, V., Sisti, M., Slocum, P., Speller, D., Surukuchi, P. T., Taffarello, L., Tomei, C., Torres, J., Tretyak, V. I., Tsymbaliuk, A., Velazquez, M., Vetter, K. J., Wagaarachchi, S. L., Wang, G., Wang, L., Wang, R., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Xue, M., Yan, L., Yang, J., Yefremenko, V., Umatov, V. I., Zarytskyy, M. M., Zhang, J., Zolotarova, A., and Zucchelli, S.
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Nuclear Experiment - Abstract
Current experiments to search for broken lepton-number symmetry through the observation of neutrinoless double-beta decay ($0\mathrm{\nu\beta\beta}$) provide the most stringent limits on the Majorana nature of neutrinos and the effective Majorana neutrino mass ($m_{\beta\beta}$). The next-generation experiments will focus on the sensitivity to the $0\mathrm{\nu\beta\beta}$ half-life of $\mathcal{O}(10^{27}$--$10^{28}$~years$)$ and $m_{\beta\beta}\lesssim15$~meV, which would provide complete coverage of the so-called Inverted Ordering region of the neutrino mass parameter space. By taking advantage of recent technological breakthroughs, new, future calorimetric experiments at the 1-ton scale can increase the sensitivity by at least another order of magnitude, exploring the large fraction of the parameter space that corresponds to the Normal neutrino mass ordering. In case of a discovery, such experiments could provide important insights toward a new understanding of the mechanism of $0\mathrm{\nu\beta\beta}$. We present here a series of projects underway that will provide advancements in background reduction, cryogenic readout, and physics searches beyond $0\mathrm{\nu\beta\beta}$, all moving toward the next-to-next generation CUPID-1T detector., Comment: contribution to Snowmass 2021
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- 2022
155. Electronic structure of the highly conductive perovskite oxide SrMoO$_3$
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Cappelli, E., Hampel, A., Chikina, A., Guedes, E. Bonini, Gatti, G., Hunter, A., Issing, J., Biskup, N., Varela, M., Dreyer, Cyrus E., Tamai, A., Georges, A., Bruno, F. Y., Radovic, M., and Baumberger, F.
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Condensed Matter - Strongly Correlated Electrons - Abstract
We use angle-resolved photoemission to map the Fermi surface and quasiparticle dispersion of bulk-like thin films of SrMoO$_3$ grown by pulsed laser deposition. The electronic self-energy deduced from our data reveals weak to moderate correlations in SrMoO$_3$, consistent with our observation of well-defined electronic states over the entire occupied band width. We further introduce spectral function calculations that combine dynamical mean-field theory with an unfolding procedure of density functional calculations and demonstrate good agreement of this approach with our experiments.
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- 2022
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156. Inverse design of plasma metamaterial devices with realistic elements
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Rodriguez, Jesse A and Cappelli, Mark A.
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Physics - Applied Physics ,Physics - Optics ,Physics - Plasma Physics - Abstract
In an expansion of a previous study [1], we apply inverse design methods to produce two-dimensional plasma metamaterial devices with realistic plasma elements which incorporate quartz envelopes, collisionality (loss), non-uniform density profiles, and resistance to experimental error/perturbation. Backpropagated finite difference frequency domain simulations are used to design waveguides and demultiplexers operating under the transverse magnetic polarization. Optimal devices with realistic elements are compared to previous devices with idealized elements, and several parameter initialization schemes for the optimization algorithm are explored. Demultiplexing and waveguiding are demonstrated for microwave-regime devices composed of plasma elements with reasonable space-averaged plasma frequencies ~10 GHz and a collision frequency ~1 GHz, allowing for future in-situ training and experimental realization of these designs., Comment: 9 pages, 9 figures
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- 2022
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157. New Direct Limit on Neutrinoless Double Beta Decay Half-Life of Te128 with CUORE
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Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Beretta, M, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camilleri, J, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Capelli, C, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Celi, E, Chiesa, D, Clemenza, M, Copello, S, Cremonesi, O, Creswick, RJ, D’Addabbo, A, Dafinei, I, Del Corso, F, Dell’Oro, S, Di Domizio, S, Di Lorenzo, S, Dompè, V, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fu, SH, Fujikawa, BK, Ghislandi, S, Giachero, A, Gianvecchio, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Hansen, EV, Heeger, KM, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, Yu G, Kowalski, R, Liu, R, Ma, L, G., Y, Marini, L, Maruyama, RH, Mayer, D, Mei, Y, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, EB, Nucciotti, A, Nutini, I, O’Donnell, T, Olmi, M, Ouellet, JL, Pagan, S, Pagliarone, CE, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Quitadamo, S, Ressa, A, Rosenfeld, C, Sangiorgio, S, and Schmidt, B
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Nuclear and Plasma Physics ,Particle and High Energy Physics ,Physical Sciences ,Half-Life ,Bayes Theorem ,Granisetron ,CUORE Collaboration ,Mathematical Sciences ,Engineering ,General Physics ,Mathematical sciences ,Physical sciences - Abstract
The Cryogenic Underground Observatory for Rare Events (CUORE) at Laboratori Nazionali del Gran Sasso of INFN in Italy is an experiment searching for neutrinoless double beta (0νββ) decay. Its main goal is to investigate this decay in ^{130}Te, but its ton-scale mass and low background make CUORE sensitive to other rare processes as well. In this Letter, we present our first results on the search for 0νββ decay of ^{128}Te, the Te isotope with the second highest natural isotopic abundance. We find no evidence for this decay, and using a Bayesian analysis we set a lower limit on the ^{128}Te 0νββ decay half-life of T_{1/2}>3.6×10^{24} yr (90% CI). This represents the most stringent limit on the half-life of this isotope, improving by over a factor of 30 the previous direct search results, and exceeding those from geochemical experiments for the first time.
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- 2022
158. An energy-dependent electro-thermal response model of CUORE cryogenic calorimeter
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Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Beretta, M, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camilleri, J, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Capelli, C, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Celi, E, Chiesa, D, Clemenza, M, Copello, S, Cremonesi, O, Creswick, RJ, D'Addabbo, A, Dafinei, I, Del Corso, F, Dell'Oro, S, Di Domizio, S, Di Lorenzo, S, Dompè, V, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fu, SH, Fujikawa, BK, Ghislandi, S, Giachero, A, Gianvecchio, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Hansen, EV, Heeger, KM, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, Yu G, Kowalski, R, Li, M, Liu, R, Ma, L, Ma, YG, Marini, L, Maruyama, RH, Mayer, D, Mei, Y, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, EB, Nucciotti, A, Nutini, I, O'Donnell, T, Olmi, M, Ouellet, JL, Pagan, S, Pagliarone, CE, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Quitadamo, S, Ressa, A, Rosenfeld, C, and Sangiorgio, S
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Nuclear and Plasma Physics ,Synchrotrons and Accelerators ,Physical Sciences ,Cryogenic detectors ,Detector modelling and simulations I (interaction of radiation with matter ,interaction of photons with matter ,interaction of hadrons with matter etc) ,Double-beta decay detectors ,Engineering ,Nuclear & Particles Physics ,Physical sciences - Abstract
The Cryogenic Underground Observatory for Rare Events (CUORE) is the most sensitive experiment searching for neutrinoless double-beta decay (0νββ) in 130Te. CUORE uses a cryogenic array of 988 TeO2 calorimeters operated at ∼10 mK with a total mass of 741 kg. To further increase the sensitivity, the detector response must be well understood. Here, we present a non-linear thermal model for the CUORE experiment on a detector-by-detector basis. We have examined both equilibrium and dynamic electro-thermal models of detectors by numerically fitting non-linear differential equations to the detector data of a subset of CUORE channels which are well characterized and representative of all channels. We demonstrate that the hot-electron effect and electric-field dependence of resistance in NTD-Ge thermistors alone are inadequate to describe our detectors' energy-dependent pulse shapes. We introduce an empirical second-order correction factor in the exponential temperature dependence of the thermistor, which produces excellent agreement with energy-dependent pulse shape data up to 6 MeV. We also present a noise analysis using the fitted thermal parameters and show that the intrinsic thermal noise is negligible compared to the observed noise for our detectors.
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- 2022
159. ATHENA detector proposal — a totally hermetic electron nucleus apparatus proposed for IP6 at the Electron-Ion Collider
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Adam, J, Adamczyk, L, Agrawal, N, Aidala, C, Akers, W, Alekseev, M, Allen, MM, Ameli, F, Angerami, A, Antonioli, P, Apadula, NJ, Aprahamian, A, Armstrong, W, Arratia, M, Arrington, JR, Asaturyan, A, Aschenauer, EC, Augsten, K, Aune, S, Bailey, K, Baldanza, C, Bansal, M, Barbosa, F, Barion, L, Barish, K, Battaglieri, M, Bazilevsky, A, Behera, NK, Berdnikov, V, Bernauer, J, Berriaud, C, Bhasin, A, Bhattacharya, DS, Bielcik, J, Bielcikova, J, Bissolotti, C, Boeglin, W, Bondì, M, Borri, M, Bossù, F, Bouyjou, F, Brandenburg, JD, Bressan, A, Brooks, M, Bültmann, SL, Byer, D, Caines, H, de la Barca Sanchez, M Calderon, Calvelli, V, Camsonne, A, Cappelli, L, Capua, M, Castro, M, Cavazza, D, Cebra, D, Celentano, A, Chakaberia, I, Chan, B, Chang, W, Chartier, M, Chatterjee, C, Chen, D, Chen, J, Chen, K, Chen, Z, Chetri, H, Chiarusi, T, Chiosso, M, Chu, X, Chwastowski, JJ, Cicala, G, Cisbani, E, Cline, E, Cloët, I, Colella, D, Contalbrigo, M, Contin, G, Corliss, R, Corrales-Morales, Y, Crafts, J, Crawford, C, Cruz-Torres, R, D'Ago, D, D'Angelo, A, D'Hose, N, Dainton, J, Torre, S Dalla, Dasgupta, SS, Dash, S, Dashyan, N, Datta, J, Daugherity, M, De Vita, R, Deconinck, W, Defurne, M, Dehmelt, K, Del Dotto, A, Delcarro, F, Dellacasa, G, and Demiroglu, ZS
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Nuclear and Plasma Physics ,Physical Sciences ,Large detector systems for particle and astroparticle physics ,Calorimeters ,Cherenkov detectors ,Particle tracking detectors ,Engineering ,Nuclear & Particles Physics ,Physical sciences - Abstract
ATHENA has been designed as a general purpose detector capable of delivering the full scientific scope of the Electron-Ion Collider. Careful technology choices provide fine tracking and momentum resolution, high performance electromagnetic and hadronic calorimetry, hadron identification over a wide kinematic range, and near-complete hermeticity. This article describes the detector design and its expected performance in the most relevant physics channels. It includes an evaluation of detector technology choices, the technical challenges to realizing the detector and the R&D required to meet those challenges.
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- 2022
160. NOS1AP is a novel molecular target and critical factor in TDP-43 pathology
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Cappelli, Sara, Spalloni, Alida, Feiguin, Fabian, Visani, Giulia, Šušnjar, Urša, Brown, Anna-Leigh, Phatnani, Hemali, Kwan, Justin, Sareen, Dhruv, Broach, James R, Simmons, Zachary, Arcila-Londono, Ximena, Lee, Edward B, Van Deerlin, Vivianna M, Shneider, Neil A, Fraenkel, Ernest, Ostrow, Lyle W, Baas, Frank, Zaitlen, Noah, Berry, James D, Malaspina, Andrea, Fratta, Pietro, Cox, Gregory A, Thompson, Leslie M, Finkbeiner, Steve, Dardiotis, Efthimios, Miller, Timothy M, Chandran, Siddharthan, Pal, Suvankar, Hornstein, Eran, MacGowan, Daniel J, Heiman-Patterson, Terry, Hammell, Molly G, Patsopoulos, Nikolaos A, Butovsky, Oleg, Dubnau, Joshua, Nath, Avindra, Bowser, Robert, Harms, Matt, Aronica, Eleonora, Poss, Mary, Phillips-Cremins, Jennifer, Crary, John, Atassi, Nazem, Lange, Dale J, Adams, Darius J, Stefanis, Leonidas, Gotkine, Marc, Baloh, Robert H, Babu, Suma, Raj, Towfique, Paganoni, Sabrina, Shalem, Ophir, Smith, Colin, Zhang, Bin, Harris, Brent, Broce, Iris, Drory, Vivian, Ravits, John, McMillan, Corey, Menon, Vilas, De Bardi, Marco, Borsellino, Giovanna, Secrier, Maria, Romano, Maurizio, Longone, Patrizia, and Buratti, Emanuele
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Biomedical and Clinical Sciences ,Neurosciences ,Clinical Sciences ,Biotechnology ,Genetics ,Aetiology ,2.1 Biological and endogenous factors ,NYGC ALS Consortium ,ALS ,CAPON/NOS1AP ,RNA stability ,TDP-43 ,hnRNPs ,Clinical sciences ,Biological psychology - Abstract
Many lines of evidence have highlighted the role played by heterogeneous nuclear ribonucleoproteins in amyotrophic lateral sclerosis. In this study, we have aimed to identify transcripts co-regulated by TAR DNA-binding protein 43 kDa and highly conserved heterogeneous nuclear ribonucleoproteins which have been previously shown to regulate TAR DNA-binding protein 43 kDa toxicity (deleted in azoospermia-associated protein 1, heterogeneous nuclear ribonucleoprotein -Q, -D, -K and -U). Using the transcriptome analyses, we have uncovered that Nitric Oxide Synthase 1 Adaptor Protein mRNA is a direct TAR DNA-binding protein 43 kDa target, and in flies, its modulation alone can rescue TAR DNA-binding protein 43 kDa pathology. In primary mouse cortical neurons, we show that TAR DNA-binding protein 43 kDa mediated downregulation of Nitric Oxide Synthase 1 Adaptor Protein expression strongly affects the NMDA-receptor signalling pathway. In human patients, the downregulation of Nitric Oxide Synthase 1 Adaptor Protein mRNA strongly correlates with TAR DNA-binding protein 43 kDa proteinopathy as measured by cryptic Stathmin-2 and Unc-13 homolog A cryptic exon inclusion. Overall, our results demonstrate that Nitric Oxide Synthase 1 Adaptor Protein may represent a novel disease-relevant gene, potentially suitable for the development of new therapeutic strategies.
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- 2022
161. Evaluation of attenuated Salmonella Typhimurium (STMΔznuABC) anticancer activity on canine mammary cancer-associated fibroblasts
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Chirullo, Barbara, Fruscione, Floriana, Del Zotto, Genny, Dell'Anno, Filippo, Tarantino, Michela, Porcellato, Ilaria, Petrucci, Paola, De Ciucis, Chiara Grazia, Bufalari, Antonello, Guardone, Lisa, Cappelli, Katia, Moretti, Giulia, Mecocci, Samanta, Monti, Eleonora, De Paolis, Livia, and Razzuoli, Elisabetta
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- 2024
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162. Occurrence of short- and ultra-short chain PFAS in drinking water from Flanders (Belgium) and implications for human exposure
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Cappelli, Francesca, Ait Bamai, Yu, Van Hoey, Kobe, Kim, Da-Hye, and Covaci, Adrian
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- 2024
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163. Impact of the Noninvasive Diagnostic Algorithm on Clinical Presentation and Prognosis in Cardiac Amyloidosis
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Tini, Giacomo, Cristiano, Ernesto, Zampieri, Mattia, Ponziani, Alberto, Porcari, Aldostefano, Zanoletti, Margherita, Mazzoni, Carlotta, Sclafani, Matteo, Saturi, Giulia, Lalario, Andrea, Labate, Marianna Eleonora, Autore, Camillo, Barbato, Emanuele, Perfetto, Federico, Biagini, Elena, Sinagra, Gianfranco, Canepa, Marco, Merlo, Marco, Longhi, Simone, Cappelli, Francesco, and Musumeci, Beatrice
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- 2024
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164. Novel multitarget directed ligands inspired by riluzole: A serendipitous synthesis of substituted benzo[b][1,4]thiazepines potentially useful as neuroprotective agents
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Maramai, Samuele, Saletti, Mario, Paolino, Marco, Giuliani, Germano, Cazzola, Jessica, Spaiardi, Paolo, Talpo, Francesca, Frosini, Maria, Pifferi, Alice, Ballarotto, Marco, Carotti, Andrea, Poggialini, Federica, Vagaggini, Chiara, Dreassi, Elena, Giorgi, Gianluca, Dondio, Giulio, Cappelli, Andrea, Rosario Biella, Gerardo, and Anzini, Maurizio
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- 2024
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165. Baseline single institutional retrospective review of body mass index (BMI) as a prognostic indicator in patients with newly diagnosed glioblastoma (GBM)
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Cappelli, Louis, Uppendahl, Adam, Gardner, Christopher, Khan, Mehak, Kayne, Allison, Vemula, Sudheshna, Poiset, Spencer J., Zhan, Tinging, Judy, Kevin D., Andrews, David W., Simone, Nicole L., Alnahhas, Iyad, and Shi, Wenyin
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- 2024
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166. Comprehensive Geriatric Assessment to Optimize the Management of Older Patients With Transthyretin Cardiac Amyloidosis
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Fumagalli, Carlo, Maurer, Mathew S., Fontana, Marianna, Fine, Nowell, Gillmore, Julian, Goyal, Parag, Nakagawa, Shunichi, Musumeci, Beatrice, Grogan, Martha, Marfella, Raffaele, Limongelli, Giuseppe, Bo, Mario, Longhi, Simone, Cuddy, Sarah, Masri, Ahmad, Olivotto, Iacopo, Perfetto, Federico, Ungar, Andrea, Marchionni, Niccolò, and Cappelli, Francesco
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- 2024
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167. Efficacy and safety of ramucirumab plus carboplatin and paclitaxel in untreated metastatic thymic carcinoma: RELEVENT phase II trial (NCT03921671)
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Proto, C., Ganzinelli, M., Manglaviti, S., Imbimbo, M., Galli, G., Marabese, M., Zollo, F., Alvisi, M.F., Perrino, M., Cordua, N., Borea, F., de Vincenzo, F., Chella, A., Cappelli, S., Pardini, E., Ballatore, Z., Lucarelli, A., Ambrosini, E., Giuliano, M., Pietroluongo, E., Mulargiu, C., Fabbri, A., Prelaj, A., Occhipinti, M., Brambilla, M., Mazzeo, L., Beninato, T., Vigorito, R., Ruggirello, M., Greco, F.G., Calareso, G., Miliziano, D., Rulli, E., De Simone, I., Torri, V., de Braud, F.G.M., Pasello, G., De Placido, P., Berardi, R., Petrini, I., Zucali, P., Garassino, M.C., and Lo Russo, G.
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- 2024
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168. Use of imidazo[1,5-a]quinoline scaffold as the pharmacophore in the design of bivalent ligands of central benzodiazepine receptors
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Paolino, Marco, Saletti, Mario, Venditti, Jacopo, Castriconi, Federica, Giuliani, Germano, Maramai, Samuele, Toti, Alessandra, Ghelardini, Carla, Matucci, Rosanna, Villalobos, Narcy Alcazar, Anzini, Maurizio, and Cappelli, Andrea
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- 2025
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169. Anti–Peptidylarginine Deiminase 4 Autoantibodies and Disease Duration as Predictors of Treatment Response in Rheumatoid Arthritis
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Laura C. Cappelli, David Hines, Hong Wang, Clifton O. Bingham, and Erika Darrah
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Diseases of the musculoskeletal system ,RC925-935 - Abstract
Background Given that autoantibodies to peptidylarginine deiminase 4 (PAD4) are associated with erosive disease in established rheumatoid arthritis (RA), this study was conducted to compare the clinical and prognostic use of anti‐PAD4 antibodies in patients with early and established RA. Methods Sera from patients with early (duration
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- 2024
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170. No Feature Left Behind: Filling the Gap in Fingerprint Frequency Estimation
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Raffaele Cappelli
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Benchmark testing ,biometrics (access control) ,convolutional neural networks ,deep learning ,feature extraction ,fingerprint recognition ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 - Abstract
Fingerprint recognition remains a cornerstone of biometric identification systems. However, the critical task of ridge-line frequency estimation has been surprisingly underexplored. To address this research gap, I introduce the first publicly available benchmark for fingerprint frequency estimation, a pioneering resource that includes both high- and low-quality fingerprints with meticulously labeled ground truth features: segmentation masks, orientation fields, and frequency maps. Furthermore, two novel frequency estimation methods are proposed: one that significantly enhances a well-known frequency estimation method based on traditional image processing techniques and another that, for the first time, applies deep learning to this context. Experimental results on the new benchmark demonstrate that both methods surpass existing state-of-the-art techniques, particularly in challenging low-quality fingerprint scenarios. By providing an open-source implementation and a comprehensive benchmark, this work sets a new standard for the evaluation of frequency estimation methods, fostering further research and development in this crucial area of fingerprint recognition.
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- 2024
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171. Exploring the Power of Simplicity: A New State-of-the-Art in Fingerprint Orientation Field Estimation
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Raffaele Cappelli
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Fingerprints ,orientation field estimation ,KISS principle ,FOE benchmarks ,NIST SD27 ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 - Abstract
Fingerprint recognition is an important tool for personal identification due to its versatility, user-friendliness, and accuracy. Fingerprint orientation field estimation, a crucial step in fingerprint feature extraction, significantly impacts recognition performance. While numerous methods have been proposed, achieving state-of-the-art accuracy often comes at the cost of increased complexity, hindering practical implementation. This work addresses this challenge by introducing two novel, simple, and efficient fingerprint orientation field estimation methods: GBFOE and SNFOE. Both methods adhere to the KISS (Keep It Simple and Straightforward) principle, achieving remarkable performance on publicly available benchmarks. GBFOE outperforms all local methods and rivals more complex approaches, while SNFOE establishes itself as a new state-of-the-art, achieving the highest accuracy on all datasets in both evaluated benchmarks. Surpassing methods designed specifically for latent fingerprints, SNFOE demonstrates exceptional performance on this challenging task within the evaluated benchmarks, highlighting its generalizability despite not being trained on such data. These results underline the potential of simple and efficient methods in fingerprint orientation field estimation, paving the way for practical and resource-efficient fingerprint recognition systems. An open-source Python implementation of both methods is available, fostering further research and development in this field.
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- 2024
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172. Optimization of the first CUPID detector module
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CUPID collaboration, Armatol, A., Augier, C., Avignone III, F. T., Azzolini, O., Balata, M., Ballen, K., Barabash, A. S., Bari, G., Barresi, A., Baudin, D., Bellini, F., Benato, G., Beretta, M., Bettelli, M., Biassoni, M., Billard, J., Boldrini, V., Branca, A., Brofferio, C., Bucci, C., Camilleri, J., Capelli, C., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Celi, E., Chang, C., Chiesa, D., Clemenza, M., Colantoni, I., Copello, S., Craft, E., Cremonesi, O., Creswick, R. J., Cruciani, A., D'Addabbo, A., D'Imperio, G., Dabagov, S., Dafinei, I., Danevich, F. A., De Jesus, M., de Marcillac, P., Dell'Oro, S., Di Domizio, S., Di Lorenzo, S., Dixon, T., Dompè, V., Drobizhev, A., Dumoulin, L., Fantini, G., Faverzani, M., Ferri, E., Ferri, F., Ferroni, F., Figueroa-Feliciano, E., Foggetta, L., Formaggio, J., Franceschi, A., Fu, C., Fu, S., Fujikawa, B. K., Gallas, A., Gascon, J., Ghislandi, S., Giachero, A., Gianvecchio, A., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Grant, C., Gras, P., Guillaumon, P. V., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Helis, D. L., Huang, H. Z., Huang, R. G., Imbert, L., Johnston, J., Juillard, A., Karapetrov, G., Keppel, G., Khalife, H., Kobychev, V. V., Kolomensky, Yu. G., Konovalov, S. I., Kowalski, R., Langford, T., Lefevre, M ., Liu, R., Liu, Y., Loaiza, P., Ma, L., Madhukuttan, M., Mancarella, F., Marini, L., Marnieros, S., Martinez, M., Maruyama, R. H., Mas, Ph., Mauri, B., Mayer, D., Mazzitelli, G., Mei, Y., Milana, S., Morganti, S., Napolitano, T., Nastasi, M., Nikkel, J., Nisi, S., Nones, C., Norman, E. B., Novosad, V., Nutini, I., O'Donnell, T., Olivieri, E., Olmi, M., Ouellet, J. L., Pagan, S., Pagliarone, C., Pagnanini, L., Pattavina, L., Pavan, M., Peng, H., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Poda, D. V., Polischuk, O. G., Ponce, I., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Ressa, A., Rizzoli, R., Rosenfeld, C., Rosier, P., Scarpaci, J., Schmidt, B., Sharma, V., Shlegel, V., Singh, V., Sisti, M., Slocum, P., Speller, D., Surukuchi, P. T., Taffarello, L., Tomei, C., Torres, J., Tretyak, V. I., Tsymbaliuk, A., Velazquez, M., Vetter, K. J., Wagaarachchi, S. L., Wang, G., Wang, L., Wang, R., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Xue, M., Yan, L., Yang, J., Yefremenko, V., Umatov, V. I., Zarytskyy, M. M., Zhang, J., Zolotarova, A., and Zucchelli, S.
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Physics - Instrumentation and Detectors ,Nuclear Experiment - Abstract
CUPID will be a next generation experiment searching for the neutrinoless double $\beta$ decay, whose discovery would establish the Majorana nature of the neutrino. Based on the experience achieved with the CUORE experiment, presently taking data at LNGS, CUPID aims to reach a background free environment by means of scintillating Li$_{2}$$^{100}$MoO$_4$ crystals coupled to light detectors. Indeed, the simultaneous heat and light detection allows us to reject the dominant background of $\alpha$ particles, as proven by the CUPID-0 and CUPID-Mo demonstrators. In this work we present the results of the first test of the CUPID baseline module. In particular, we propose a new optimized detector structure and light sensors design to enhance the engineering and the light collection, respectively. We characterized the heat detectors, achieving an energy resolution of (5.9 $\pm$ 0.2) keV FWHM at the $Q$-value of $^{100}$Mo (about 3034 keV). We studied the light collection of the baseline CUPID design with respect to an alternative configuration which features gravity-assisted light detectors' mounting. In both cases we obtained an improvement in the light collection with respect to past measures and we validated the particle identification capability of the detector, which ensures an $\alpha$ particle rejection higher than 99.9%, fully satisfying the requirements for CUPID., Comment: 10 pages, 5 figures
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- 2022
173. Streaming readout for next generation electron scattering experiment
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Ameli, Fabrizio, Battaglieri, Marco, Berdnikov, Vladimir V., Bondì, Mariangela, Boyarinov, Sergey, Brei, Nathan, Cappelli, Laura, Celentano, Andrea, Chiarusi, Tommaso, De Vita, Raffaella, Fanelli, Cristiano, Gyurjyan, Vardan, Lawrence, David, Moran, Patrick, Musico, Paolo, Pellegrino, Carmelo, Pilloni, Alessandro, Raydo, Ben, Timmer, Carl, Ungaro, Maurizio, and Vallarino, Simone
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Physics - Instrumentation and Detectors ,Nuclear Experiment - Abstract
Current and future experiments at the high intensity frontier are expected to produce an enormous amount of data that needs to be collected and stored for offline analysis. Thanks to the continuous progress in computing and networking technology, it is now possible to replace the standard `triggered' data acquisition systems with a new, simplified and outperforming scheme. `Streaming readout' (SRO) DAQ aims to replace the hardware-based trigger with a much more powerful and flexible software-based one, that considers the whole detector information for efficient real-time data tagging and selection. Considering the crucial role of DAQ in an experiment, validation with on-field tests is required to demonstrate SRO performance. In this paper we report results of the on-beam validation of the Jefferson Lab SRO framework. We exposed different detectors (PbWO-based electromagnetic calorimeters and a plastic scintillator hodoscope) to the Hall-D electron-positron secondary beam and to the Hall-B production electron beam, with increasingly complex experimental conditions. By comparing the data collected with the SRO system against the traditional DAQ, we demonstrate that the SRO performs as expected. Furthermore, we provide evidence of its superiority in implementing sophisticated AI-supported algorithms for real-time data analysis and reconstruction.
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- 2022
174. The Results of the URRAH (Uric Acid Right for Heart Health) Project: A Focus on Hyperuricemia in Relation to Cardiovascular and Kidney Disease and its Role in Metabolic Dysregulation
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Maloberti, Alessandro, Mengozzi, Alessandro, Russo, Elisa, Cicero, Arrigo Francesco Giuseppe, Angeli, Fabio, Agabiti Rosei, Enrico, Barbagallo, Carlo Maria, Bernardino, Bruno, Bombelli, Michele, Cappelli, Federica, Casiglia, Edoardo, Cianci, Rosario, Ciccarelli, Michele, Cirillo, Massimo, Cirillo, Pietro, Desideri, Giovambattista, D’Elia, Lanfranco, Dell’Oro, Raffaella, Facchetti, Rita, Ferri, Claudio, Galletti, Ferruccio, Giannattasio, Cristina, Gesualdo, Loreto, Iaccarino, Guido, Lippa, Luciano, Mallamaci, Francesca, Masi, Stefano, Masulli, Maria, Mazza, Alberto, Muiesan, Maria Lorenza, Nazzaro, Pietro, Parati, Gianfranco, Palatini, Paolo, Pauletto, Paolo, Pontremoli, Roberto, Pugliese, Nicola Riccardo, Quarti-Trevano, Fosca, Rattazzi, Marcello, Reboldi, Gianpaolo, Rivasi, Giulia, Salvetti, Massimo, Tikhonoff, Valerie, Tocci, Giuliano, Ungar, Andrea, Verdecchia, Paolo, Viazzi, Francesca, Volpe, Massimo, Virdis, Agostino, Grassi, Guido, and Borghi, Claudio
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- 2023
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175. Role of Body Composition in the Prediction of Skeletal Fragility Induced by Hormone Deprivation Therapies in Cancer Patients
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Dalla Volta, Alberto, Caramella, Irene, Di Mauro, Pierluigi, Bergamini, Marco, Cosentini, Deborah, Valcamonico, Francesca, Cappelli, Carlo, Laganà, Marta, Di Meo, Nunzia, Farina, Davide, Pedersini, Rebecca, Mazziotti, Gherardo, and Berruti, Alfredo
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- 2023
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176. Investigating the origins of differentiated vulnerabilities to climate change through the lenses of the Capability Approach
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Cappelli, Federica
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- 2023
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177. The longitudinal progression of MRI changes in pre-ataxic carriers of SCA3/MJD
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de Oliveira, Camila Maria, Leotti, Vanessa Bielefeldt, Polita, Sandra, Anes, Mauricio, Cappelli, Amanda Henz, Rocha, Anastacia Guimarães, Ecco, Gabriela, Bolzan, Gabriela, Kersting, Nathalia, Duarte, Juliana Avila, Saraiva-Pereira, Maria-Luiza, Junior, Marcondes Cavalcante França, Rezende, Thiago Junqueira Ribeiro, and Jardim, Laura Bannach
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- 2023
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178. Direct Apical Cannulation With Protek Duo Rapid Deployment Cannula via Mini Thoracotomy for Ambulatory Venoarterial-Extracorporeal Membrane Oxygenation
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Cappelli, Jared, Emling, Jonathan, Edwards, Amber, and Babu, Ashok
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- 2024
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179. REDISCOVER International Guidelines on the Perioperative Care of Surgical Patients With Borderline-resectable and Locally Advanced Pancreatic Cancer
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Boggi, Ugo, Kauffmann, Emanuele, Napoli, Niccolò, Barreto, S. George, Besselink, Marc G., Fusai, Giuseppe K., Hackert, Thilo, Abu Hilal, Mohammad, Marchegiani, Giovanni, Salvia, Roberto, Shrikhande, Shailesh V., Truty, Mark, Werner, Jens, Wolfgang, Christopher L., Bannone, Elisa, Capretti, Giovanni, Cattelani, Alice, Coppola, Alessandro, Cucchetti, Alessandro, De Sio, Davide, Di Dato, Armando, Di Meo, Giovanna, Fiorillo, Claudio, Gianfaldoni, Cesare, Ginesini, Michael, Hidalgo Salinas, Camila, Lai, Quirino, Miccoli, Mario, Montorsi, Roberto, Pagnanelli, Michele, Poli, Andrea, Ricci, Claudio, Sucameli, Francesco, Tamburrino, Domenico, Viti, Virginia, Addeo, Pietro F., Alfieri, Sergio, Bachellier, Philippe, Baiocchi, Gian Luca, Balzano, Gianpaolo, Barbarello, Linda, Brolese, Alberto, Busquets, Juli, Butturini, Giovanni, Caniglia, Fabio, Caputo, Damiano, Casadei, Riccardo, Chunhua, Xi, Colangelo, Ettore, Coratti, Andrea, Costa, Francesca, Crafa, Francesco, Dalla Valle, Raffaele, De Carlis, Luciano, de Wilde, Roeland F., Del Chiaro, Marco, Di Benedetto, Fabrizio, Di Sebastiano, Pierluigi, Dokmak, Safi, Hogg, Melissa, Egorov, Vyacheslav I., Ercolani, Giorgio, Ettorre, Giuseppe Maria, Falconi, Massimo, Ferrari, Giovanni, Ferrero, Alessandro, Filauro, Marco, Giardino, Alessandro, Grazi, Gian Luca, Gruttadauria, Salvatore, Izbicki, Jakob R, Jovine, Elio, Katz, Matthew, Keck, Tobias, Khatkov, Igor, Kiguchi, Gozo, Kooby, David, Lang, Hauke, Lombardo, Carlo, Malleo, Giuseppe, Massani, Marco, Mazzaferro, Vincenzo, Memeo, Riccardo, Miao, Yi, Mishima, Kohei, Molino, Carlo, Nagakawa, Yuichi, Nakamura, Masafumi, Nardo, Bruno, Panaro, Fabrizio, Pasquali, Claudio, Perrone, Vittorio, Rangelova, Elena, Liu, Rong, Romagnoli, Renato, Romito, Raffaele, Rosso, Edoardo, Schulick, Richard, Siriwardena, Ajith, Spampinato, Marcello Giuseppe, Strobel, Oliver, Testini, Mario, Troisi, Roberto Ivan, Uzunoglo, Faik G., Valente, Roberto, Veneroni, Luigi, Zerbi, Alessandro, Vicente, Emilio, Vistoli, Fabio, Vivarelli, Marco, Wakabayashi, Go, Zanus, Giacomo, Zureikat, Amer, Zyromski, Nicholas J., Coppola, Roberto, D’Andrea, Vito, Davide, José, Dervenis, Christos, Frigerio, Isabella, Konlon, Kevin C., Michelassi, Fabrizio, Montorsi, Marco, Nealon, William, Portolani, Nazario, Sousa Silva, Donzília, Bozzi, Giuseppe, Ferrari, Viviana, Trivella, Maria G., Cameron, John, Clavien, Pierre-Alain, Asbun, Horacio J., Boraschi, Piero, Campani, Daniela, Cappelli, Carla, Cioni, Roberto, Dominici, Massimo, Esposito, Irene, Gambacorta, Maria A, Marciano, Emanuele, Masi, Gianluca, Morganti, Alessio, Mutignani, Massimiliano, Neri, Emanuele, Paiar, Fabiola, Reni, Michele, Rotondo, Maria Isabella, Silvestris, Nicola, Tortora, Giampaolo, Vasile, Enrico, and Volterrani, Duccio
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- 2024
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180. Robotic Versus Open Pancreatoduodenectomy With Vein Resection and Reconstruction: A Propensity Score-Matched Analysis
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Napoli, Niccolò, Kauffmann, Emanuele Federico, Ginesini, Michael, Di Dato, Armando, Viti, Virginia, Gianfaldoni, Cesare, Lami, Lucrezia, Cappelli, Carla, Rotondo, Maria Isabella, Campani, Daniela, Amorese, Gabriella, Vivaldi, Caterina, Cesario, Silvia, Bernardini, Laura, Vasile, Enrico, Vistoli, Fabio, and Boggi, Ugo
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- 2024
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181. Author Correction: Location and function of TDP-43 in platelets, alterations in neurodegenerative diseases and arising considerations for current plasma biobank protocols
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Ruth Luthi-Carter, Sara Cappelli, Morgan Le Roux-Bourdieu, Noemie Tentillier, James P. Quinn, Tiziana Petrozziello, Lathika Gopalakrishnan, Purva Sethi, Himanshi Choudhary, Giorgia Bartolini, Elias Gebara, Cristiana Stuani, Laure Font, Jiyan An, Vanessa Ortega, Jessica Sage, Edina Kosa, Bianca A. Trombetta, Roberto Simeone, Tamara Seredenina, Tariq Afroz, James D. Berry, Steven E. Arnold, Becky C. Carlyle, Oskar Adolfsson, Ghazaleh Sadri-Vakili, Emanuele Buratti, Robert Bowser, and Abdulbaki Agbas
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Medicine ,Science - Published
- 2024
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182. Vacuum-Assisted MonoTrapTM Extraction for Volatile Organic Compounds (VOCs) Profiling from Hot Mix Asphalt
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Stefano Dugheri, Giovanni Cappelli, Niccolò Fanfani, Donato Squillaci, Ilaria Rapi, Lorenzo Venturini, Chiara Vita, Riccardo Gori, Piero Sirini, Domenico Cipriano, Mieczyslaw Sajewicz, and Nicola Mucci
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hot mix asphalt ,monolithic material sorptive extraction ,under vacuum extraction ,volatile organic compounds ,odor emission ,gas chromatography-mass spectrometry ,Organic chemistry ,QD241-441 - Abstract
MonoTrapTM was introduced in 2009 as a novel miniaturized configuration for sorptive sampling. The method for the characterization of volatile organic compound (VOC) emission profiles from hot mix asphalt (HMA) consisted of a two-step procedure: the analytes, initially adsorbed into the coating in no vacuum- or vacuum-assistance mode, were then analyzed following an automated thermal desorption (TD) step. We took advantage of the theoretical formulation to reach some conclusions on the relationship between the physical characteristics of the monolithic material and uptake rates. A total of 35 odor-active volatile compounds, determined by gas chromatography-mass spectrometry/olfactometry analysis, contributed as key odor compounds for HMA, consisting mainly of aldehydes, alcohols, and ketones. Chemometric analysis revealed that MonoTrapTM RGC18-TD was the better coating in terms of peak area and equilibrium time. A comparison of performance showed that Vac/no-Vac ratios increased, about an order of magnitude, as the boiling point of target analytes increased. The innovative hybrid adsorbent of silica and graphite carbon monolith technology, having a large surface area bonded with octadecylsilane, showed effective adsorption capability, especially to polar compounds.
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- 2024
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183. Regarding Bioanalysis Lasting a Few Minutes: Automated Cooling-SPME and Fast-GC for Urinary 2-Phenyl-2-Propanol Monitoring
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Stefano Dugheri, Niccolò Fanfani, Giovanni Cappelli, Antonio Marigliano, Elisabetta Bucaletti, Donato Squillaci, Ilaria Rapi, Lorenzo Venturini, Giulia Pizzella, Sara Manetta, Alfonso Pavone, Michele Secchi, Iacopo Rainaldi, and Nicola Mucci
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SPME ,GC–MS ,cooling SPME ,full automation ,derivatization ,cumene ,Chemical technology ,TP1-1185 - Abstract
An innovative SPME head space GC–MS method, in cooling mode, using a fully automated routine, was developed to detect 2-phenyl-2-propanol, a representative urinary metabolite of cumene. Following an acid hydrolysis and derivatization step with lowered quantities of reagents, acetic anhydride and pyridine, a 30 μm polydimethylsiloxane SPME fiber was used to sample derivatized 2-phenyl-2-propanol, such as benzenemethanol,α,α-dimethyl-acetate, from the headspace. Performances of the method, optimized through experimental design, provide an LOD of 0.034 mg/L and an LOQ 0.10 mg/L, with a short sampling time necessary per sample. The method, developed on standard solutions, will be applied to both occupationally exposed and non-exposed populations.
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- 2024
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184. Multi-Junction Solar Module and Supercapacitor Self-Powering Miniaturized Environmental Wireless Sensor Nodes
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Mara Bruzzi, Giovanni Pampaloni, Irene Cappelli, Ada Fort, Maurizio Laschi, Valerio Vignoli, and Dario Vangi
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multi-junction photovoltaic module ,supercapacitors ,wireless sensor nodes ,CO2 sensors ,self-powered sensors ,environmental gas monitoring ,Chemical technology ,TP1-1185 - Abstract
A novel prototype based on the combination of a multi-junction, high-efficiency photovoltaic (PV) module and a supercapacitor (SC) able to self-power a wireless sensor node (WSN) for outdoor air quality monitoring has been developed and tested. A PV module with about an 8 cm2 active area made of eight GaAs-based triple-junction solar cells with a nominal 29% efficiency was assembled and characterized under terrestrial clear-sky conditions. Energy is stored in a 4000 F/4.2 V supercapacitor with high energy capacity and a virtually infinite lifetime (104 cycles). The node power consumption was tailored to the typical power consumption of miniaturized, low-consumption NDIR CO2 sensors relying on an LED as the IR source. The charge/discharge cycles of the supercapacitor connected to the triple-junction PV module were measured under illumination with a Sun Simulator device at selected radiation intensities and different node duty cycles. Tests of the miniaturized prototype in different illumination conditions outdoors were carried out. A model was developed from the test outcomes to predict the maximum number of sensor samplings and data transmissions tolerated by the node, thus optimizing the WSN operating conditions to ensure its self-powering for years of outdoor deployment. The results show the self-powering ability of the WSN node over different insolation periods throughout the year, demonstrating its operation for a virtually unlimited lifetime without the need for battery substitution.
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- 2024
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185. Preliminary Evaluation of New Wearable Sensors to Study Incongruous Postures Held by Employees in Viticulture
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Sirio Rossano Secondo Cividino, Mauro Zaninelli, Veronica Redaelli, Paolo Belluco, Fabiano Rinaldi, Lena Avramovic, and Alessio Cappelli
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viticulture ,risk assessment ,ergonomic ,safety in agriculture ,wearable sensors ,Chemical technology ,TP1-1185 - Abstract
Musculoskeletal Disorders (MSDs) stand as a prominent cause of injuries in modern agriculture. Scientific research has highlighted a causal link between MSDs and awkward working postures. Several methods for the evaluation of working postures, and related risks, have been developed such as the Rapid Upper Limb Assessment (RULA). Nevertheless, these methods are generally applied with manual measurements on pictures or videos. As a consequence, their applicability could be scarce, and their effectiveness could be limited. The use of wearable sensors to collect kinetic data could facilitate the use of these methods for risk assessment. Nevertheless, the existing system may not be usable in the agricultural and vine sectors because of its cost, robustness and versatility to the various anthropometric characteristics of workers. The aim of this study was to develop a technology capable of collecting accurate data about uncomfortable postures and repetitive movements typical of vine workers. Specific objectives of the project were the development of a low-cost, robust, and wearable device, which could measure data about wrist angles and workers’ hand positions during possible viticultural operations. Furthermore, the project was meant to test its use to evaluate incongruous postures and repetitive movements of workers’ hand positions during pruning operations in vineyard. The developed sensor had 3-axis accelerometers and a gyroscope, and it could monitor the positions of the hand–wrist–forearm musculoskeletal system when moving. When such a sensor was applied to the study of a real case, such as the pruning of a vines, it permitted the evaluation of a simulated sequence of pruning and the quantification of the levels of risk induced by this type of agricultural activity.
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- 2024
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186. Survey of tungsten gross erosion from main plasma facing components in WEST during a L-mode high fluence campaign
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Fedorczak, N., Arnas, C., Cappelli, L., Colas, L., Corre, Y., Diez, M., Gallo, A., Gaspar, J., Grosjean, A., Guillemaut, C., Gunn, J.P., Johnson, C., Martin, C., Tsitrone, E., Unterberg, E.A., and Bucalossi, J.
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- 2024
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187. 2D kinetic-ion simulations of inverted corona fusion targets
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Riedel, William, Meezan, Nathan, Higginson, Drew, Hohenberger, Matthias, and Cappelli, Mark
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- 2024
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188. Combined portal and hepatic vein embolisation in perihilar cholangiocarcinoma
- Author
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Chevallier, Patrick, Wigmore, Stephen, Newhook, Timothy, Vauthey, Jean-Nicolas, Memeo, Riccardo, Dasari, Bobby VM., Braunwarth, Eva, Aldrighetti, Luca, Andorrà, Esteban Cugat, Arntz, Pieter, Arslan, Bulent, van Baardewijk, Laurens, Baclija, Ivan, Ball, Chad, Barbier, Louise, Bednarsch, Jan, Bemelmans, Marc, Bent, Clare, van den Bergh, Frans, Billingsley, Kevin, Binkert, Christoph, Björnsson, Bergthor, de Boer, Marieke T., Bokkers, Reinoud P.H., de Boo, Diederick, Garcia Borobia, Francisco Javier, Braat, Dries, Breen, David, Breitenstein, Stefan, Brousseau, Karine, Bruijnen, Ruther, Bruners, Philipp, Bruns, Christiane, Bunck, Alexander, Burgmans, Mark, Cappelli, Alberta, Carling, Ulrik, de Carvalho, Luis Abreu, Cha, Charles, Chan, Benjamin, Chand, Belinda, Chapelle, Thiery, De Cobelli, Franceso, Coubeau, Laurent, Criado, Eva, Croagh, Daniel, D'Hondt, Mathieu, van Dam, Ronald, Damink, Steven Olde, Davis, Rob, Delle, Martin, Denys, Alban, Deprez, Fabrice, Detry, Olivier, Dewulf, Maxime, Dili, Alexandra, Dixon, Matthew, Díaz-Nieto, Rafael, Erdmann, Joris I., Fernando, Rukshan, Font, Jaume Codina, Fouraschen, Suomi, François, Olivier, Fretland, Åsmund A., Fundora, Yilian, Gadani, Sameer, Gallinger, Steven, Geleabert, Alexandra, Gerard, Laurent, Giménez, Josep Guitart, Gobardhan, Paul, Goffette, Pierre, Grochola, Lukasz Filip, Gruenberger, Thomas, Grünhagen, Dirk, Guiliante, Felice, Gómez, Fernando, Hagendoorn, Jeroen, Hammond, John, Heijmans, Margot, Heil, Jan, Heise, Daniel, Laurens Hermie, Herrero, Eric, Hess, Gebriel, Heye, Sam, Hoffmann, Martin, Iezzi, Roberto, Imani, Farshad, James, Sinead, Jardinet, Thomas, Joshi, Kunal, Jovine, Elio, Kalil, Jennifer, Karanicolas, Paul, Kazemier, Geert, Kern, Lars, Kingham, Peter, Klass, Darren, Koerkamp, Bas Groot, Kollmar, Otto, Korenblik, Remon, Choon Kwon, Céline Lambrecht, Sven Lang, Laura-Ann, Leclercq, Wouter, van der Leij, Christiaan, Lindsay, Richard, Lopez-Ben, Santiago, Lucidi, Valerio, López, Jordi Navinés, Macdonald, Andrew, Madoff, David C., Markose, George, Maroune, Gilbert, Martel, Guillaume, Martin, Ernesto Santos, Mehrzad, Homoyon, Meijerink, Martijn, Melloul, Emmanuel, Messaoudi, Nouredin, Metrakos, Peter, Modi, Sachin, Montanari, Nicola, Moragues, Jaume Sampere, Mujoomdar, Amol, Neumann, Ulf, Oor, Jelmer, Pappas, Patroklos, Pieterman, Kay, Primrose, John, Qu, Xudong, Ratti, Francesca, Ridouani, Fourat, Borel Rinkes, Inne H.M., Casellas i Robert, Margarida, Ross, Steffen, Ruo, Leyo, Ryan, Stephen, Salik, Aysun, Sandström, Per, Santol, Jonas, Sarría, Luis, Schaarschmidt, Benedikt, Schadde, Erik, Schiesser, Marc, Schmelzle, Moritz, Seeger, Nico, Segedi, Maja, Serenari, Matteo, Gregory Sergeant, Serrablo, Alejandro, Simon, Sorina, Skaro, Anton, Smits, Maarten, Smits, Jens, Snitzbauer, Andreas, Soonawalla, Zahir, Sparrelid, Ernesto, Spuentrup, Elmar, Stavrou, Gregor, Sutcliffe, Robert, Swijnenburg, Rutger-Jan, Tancredi, Ilario, Tasse, Jordan C., Tschögl, Madita, Udupa, Venkatesha, Valenti, David A., Vass, David, van der Velden, Ariadne Lisa, Vogl, Thomas, Wacker, Frank, Wang, Xiaoying, Weitz, Jürgen, White, Steven, Widyaningsih, Rizky, De Wispelaere, Jean-François, Zijlstra, Ijsbrand, Chau, Steven, James, Sinéad, Abreu de Carvalho, Luis, Erdmann, Joris, Hermie, Laurens, and van Dam, Ronald M.
- Published
- 2024
- Full Text
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189. Search for neutrinoless β+EC decay of Te120 with CUORE
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Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Beretta, M, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camilleri, J, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, C, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Celi, E, Chiesa, D, Clemenza, M, Copello, S, Cremonesi, O, Creswick, RJ, D'Addabbo, A, Dafinei, I, Del Corso, F, Dell'Oro, S, Di Domizio, S, Di Lorenzo, S, Dompè, V, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fu, SH, Fujikawa, BK, Ghislandi, S, Giachero, A, Gianvecchio, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Hansen, EV, Heeger, KM, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, Yu G, Kowalski, R, Ligi, C, Liu, R, Ma, L, G., Y, Marini, L, Maruyama, RH, Mayer, D, Mei, Y, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, EB, Nucciotti, A, Nutini, I, O'Donnell, T, Olmi, M, Ouellet, JL, Pagan, S, Pagliarone, CE, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Quitadamo, S, Ressa, A, Rosenfeld, C, and Sakai, M
- Subjects
Nuclear and Plasma Physics ,Particle and High Energy Physics ,Synchrotrons and Accelerators ,Physical Sciences ,Cardiovascular ,Nuclear and plasma physics - Abstract
The Cryogenic Underground Observatory for Rare Events (CUORE) is a large-scale cryogenic experiment searching for neutrinoless double-beta decay (0νββ) in Te130. The CUORE detector is made of natural tellurium, providing the possibility of rare event searches on isotopes other than Te130. In this work we describe a search for neutrinoless positron-emitting electron capture (β+EC) decay in Te120 with a total TeO2 exposure of 355.7 kg yr, corresponding to 0.2405 kg yr of Te120. Albeit 0νββ with two final-state electrons represents the most promising channel, the emission of a positron and two 511-keV γ's make 0νβ+EC decay signature extremely clear. To fully exploit the potential offered by the detector modularity we include events with different topology and perform a simultaneous fit of five selected signal signatures. Using blinded data we extract a median exclusion sensitivity of 3.4×1022 yr at 90% credibility interval (C.I.). After unblinding we find no evidence of 0νβ+EC signal and set a 90% C.I. Bayesian lower limit of 2.9×1022 yr on Te120 half-life. This result improves by an order of magnitude the existing limit from the combined analysis of CUORE-0 and Cuoricino.
- Published
- 2022
190. Ennio Morricone: Il genio, l'uomo, il padre
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Marco Morricone, Valerio Cappelli
- Published
- 2024
191. The Social Network of Dante's Inferno
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Cappelli, Amedeo, Coscia, Michele, Giannotti, Fosca, Pedreschi, Dino, and Rinzivillo, Salvo
- Published
- 2011
192. Comparing Space Actors: An Empirical Assessment
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Aliberti, Marco, Cappelli, Ottorino, Praino, Rodrigo, European Space Policy Institute, Series Editor, Aliberti, Marco, Cappelli, Ottorino, and Praino, Rodrigo
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- 2023
- Full Text
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193. Measuring Space Actors: A Methodological Framework
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Aliberti, Marco, Cappelli, Ottorino, Praino, Rodrigo, European Space Policy Institute, Series Editor, Aliberti, Marco, Cappelli, Ottorino, and Praino, Rodrigo
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- 2023
- Full Text
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194. Conclusions
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Aliberti, Marco, Cappelli, Ottorino, Praino, Rodrigo, European Space Policy Institute, Series Editor, Aliberti, Marco, Cappelli, Ottorino, and Praino, Rodrigo
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- 2023
- Full Text
- View/download PDF
195. Conceptualizing Space Actors: State and Power in Space
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Aliberti, Marco, Cappelli, Ottorino, Praino, Rodrigo, European Space Policy Institute, Series Editor, Aliberti, Marco, Cappelli, Ottorino, and Praino, Rodrigo
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- 2023
- Full Text
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196. Introduction
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Aliberti, Marco, Cappelli, Ottorino, Praino, Rodrigo, European Space Policy Institute, Series Editor, Aliberti, Marco, Cappelli, Ottorino, and Praino, Rodrigo
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- 2023
- Full Text
- View/download PDF
197. PAGnol: An Extra-Large French Generative Model
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Launay, Julien, Tommasone, Elena, Pannier, Baptiste, Boniface, François, Chatelain, Amélie, Cappelli, Alessandro, Poli, Iacopo, and Seddah, Djamé
- Subjects
Computer Science - Computation and Language - Abstract
Access to large pre-trained models of varied architectures, in many different languages, is central to the democratization of NLP. We introduce PAGnol, a collection of French GPT models. Using scaling laws, we efficiently train PAGnol-XL (1.5B parameters) with the same computational budget as CamemBERT, a model 13 times smaller. PAGnol-XL is the largest model trained to date for the French language. We plan to train increasingly large and performing versions of PAGnol, exploring the capabilities of French extreme-scale models. For this first release, we focus on the pre-training and scaling calculations underlining PAGnol. We fit a scaling law for compute for the French language, and compare it with its English counterpart. We find the pre-training dataset significantly conditions the quality of the outputs, with common datasets such as OSCAR leading to low-quality offensive text. We evaluate our models on discriminative and generative tasks in French, comparing to other state-of-the-art French and multilingual models, and reaching the state of the art in the abstract summarization task. Our research was conducted on the public GENCI Jean Zay supercomputer, and our models up to the Large are made publicly available.
- Published
- 2021
198. Evidence of Josephson coupling in a few-layer black phosphorus planar Josephson junction
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Telesio, Francesca, Carrega, Matteo, Cappelli, Giulio, Iorio, Andrea, Crippa, Alessandro, Strambini, Elia, Giazotto, Francesco, Serrano-Ruiz, Manuel, Peruzzini, Maurizio, and Heun, Stefan
- Subjects
Condensed Matter - Mesoscale and Nanoscale Physics ,Quantum Physics - Abstract
Setting up strong Josephson coupling in van der Waals materials in close proximity to superconductors offers several opportunities both to inspect fundamental physics and to develop novel cryogenic quantum technologies. Here we show evidence of Josephson coupling in a planar few-layer black Phosphorus junction. The planar geometry allows us to probe the junction behavior by means of external gates, at different carrier concentrations. Clear signatures of Josephson coupling are demonstrated by measuring supercurrent flow through the junction at milli Kelvin temperatures. Manifestation of Fraunhofer pattern with a transverse magnetic field is also reported, confirming the Josephson coupling. These findings represent the first evidence of proximity Josephson coupling in a planar junction based on a van der Waals material beyond graphene and open the way to new studies, exploiting the peculiar properties of exfoliated black phosphorus thin flakes.
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- 2021
- Full Text
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199. Analog FM free-space optical communication based on a mid-infrared quantum cascade laser frequency comb
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Corrias, Nicola, Gabbrielli, Tecla, De Natale, Paolo, Consolino, Luigi, and Cappelli, Francesco
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Physics - Applied Physics ,Physics - Optics - Abstract
Quantum cascade laser frequency combs are nowadays well-appreciated sources for infrared spectroscopy. Here their applicability for free-space optical communication is demonstrated. The spontaneously-generated intermodal beat note of the frequency comb is used as carrier for transferring the analog signal via frequency modulation. Exploiting the atmospheric transparency window at 4 $\mu$m, an optical communication with a signal-to-noise ratio up to 65 dB is realized, with a modulation bandwidth of 300 kHz. The system tolerates a maximum optical attenuation exceeding 35 dB. The possibility of parallel transmission of an independent digital signal via amplitude modulation at 5 MS/s is also demonstrated., Comment: 17 pages, 13 figures
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- 2021
- Full Text
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200. Plasma-fixated nitrogen as fertilizer for turf grass
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Sze, Christina, Wang, Benjamin, Xu, Jiale, Rivas-Davila, Juan, and Cappelli, Mark A.
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Physics - Plasma Physics - Abstract
We investigated the use of plasma-fixated nitrogen, which produces nitrates (NO3-) in water, as a possible nitrogen fertilizer for recreational turf such as ryegrass and bentgrass. Experiments were carried out to study the effects of nitrate concentration on growth, the further effects of adding phosphorous (P) and potassium (K) to the plasma nitrated solution to make an N-P-K complete fertilizer, and to compare the efficacy of plasma-fixated nitrogen to sodium nitrate (NaNO3) and potassium nitrate (KNO3). The results indicate that the growth and biomass of the plants were strongly dependent on the concentration of the plasma-fixated nitrogen. Adding P-K to the plasma-fixated nitrogen improved grass growth. Grass that was supplied plasma-fixated nitrogen had improved growth compared to those supplied with equal amounts of NaNO3and KNO3. This work highlights the potential use of plasma-fixated nitrogen as a fertilizer source for commonly used turf grass.
- Published
- 2021
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