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933 results on '"Cantu, Robert C."'

152. 1757

Author

Cantu, Robert C.

Published
2005

154. 649

Author

Cantu, Robert C.

Published
2005

169. Developing methods to detect and diagnose chronic traumatic encephalopathy during life: rationale, design, and methodology for the DIAGNOSE CTE Research Project.

Author

Alosco, Michael L., Mariani, Megan L., Adler, Charles H., Balcer, Laura J., Bernick, Charles, Au, Rhoda, Banks, Sarah J., Barr, William B., Bouix, Sylvain, Cantu, Robert C., Coleman, Michael J., Dodick, David W., Farrer, Lindsay A., Geda, Yonas E., Katz, Douglas I., Koerte, Inga K., Kowall, Neil W., Lin, Alexander P., Marcus, Daniel S., and Marek, Kenneth L.

Subjects
CHRONIC traumatic encephalopathy, DIAGNOSIS, MAGNETIC resonance imaging, MEDICAL research, POSITRON emission tomography, NEUROLOGIC examination, PSYCHIATRIC epidemiology
Abstract

Background: Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease that has been neuropathologically diagnosed in brain donors exposed to repetitive head impacts, including boxers and American football, soccer, ice hockey, and rugby players. CTE cannot yet be diagnosed during life. In December 2015, the National Institute of Neurological Disorders and Stroke awarded a seven-year grant (U01NS093334) to fund the "Diagnostics, Imaging, and Genetics Network for the Objective Study and Evaluation of Chronic Traumatic Encephalopathy (DIAGNOSE CTE) Research Project." The objectives of this multicenter project are to: develop in vivo fluid and neuroimaging biomarkers for CTE; characterize its clinical presentation; refine and validate clinical research diagnostic criteria (i.e., traumatic encephalopathy syndrome [TES]); examine repetitive head impact exposure, genetic, and other risk factors; and provide shared resources of anonymized data and biological samples to the research community. In this paper, we provide a detailed overview of the rationale, design, and methods for the DIAGNOSE CTE Research Project. Methods: The targeted sample and sample size was 240 male participants, ages 45–74, including 120 former professional football players, 60 former collegiate football players, and 60 asymptomatic participants without a history of head trauma or participation in organized contact sports. Participants were evaluated at one of four U.S. sites and underwent the following baseline procedures: neurological and neuropsychological examinations; tau and amyloid positron emission tomography; magnetic resonance imaging and spectroscopy; lumbar puncture; blood and saliva collection; and standardized self-report measures of neuropsychiatric, cognitive, and daily functioning. Study partners completed similar informant-report measures. Follow-up evaluations were intended to be in-person and at 3 years post-baseline. Multidisciplinary diagnostic consensus conferences are held, and the reliability and validity of TES diagnostic criteria are examined. Results: Participant enrollment and all baseline evaluations were completed in February 2020. Three-year follow-up evaluations began in October 2019. However, in-person evaluation ceased with the COVID-19 pandemic, and resumed as remote, 4-year follow-up evaluations (including telephone-, online-, and videoconference-based cognitive, neuropsychiatric, and neurologic examinations, as well as in-home blood draw) in February 2021. Conclusions: Findings from the DIAGNOSE CTE Research Project should facilitate detection and diagnosis of CTE during life, and thereby accelerate research on risk factors, mechanisms, epidemiology, treatment, and prevention of CTE. Trial registration: NCT02798185 [ABSTRACT FROM AUTHOR]

Published
2021
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170. DS_10.1177_1941738118807122 – Supplemental material for Catastrophic High School and Collegiate Cheerleading Injuries in the United States: An Examination of the 2006-2007 Basket Toss Rule Change

Author

Yau, Rebecca K., Dennis, Savannah G., Boden, Barry P., Cantu, Robert C., A., James, and Kucera, Kristen L.

Subjects
111708 Health and Community Services, FOS: Clinical medicine, 110604 Sports Medicine, FOS: Health sciences, 110314 Orthopaedics
Abstract

Supplemental material, DS_10.1177_1941738118807122 for Catastrophic High School and Collegiate Cheerleading Injuries in the United States: An Examination of the 2006-2007 Basket Toss Rule Change by Rebecca K. Yau, Savannah G. Dennis, Barry P. Boden, Robert C. Cantu, James A. Lord and Kristen L. Kucera in Sports Health: A Multidisciplinary Approach

Published
2018
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171. Interactive Effects of Racial Identity and Repetitive Head Impacts on Cognitive Function, Structural MRI-Derived Volumetric Measures, and Cerebrospinal Fluid Tau and Aβ

Author

Alosco, Michael L., primary, Tripodis, Yorghos, additional, Koerte, Inga K., additional, Jackson, Jonathan D., additional, Chua, Alicia S., additional, Mariani, Megan, additional, Haller, Olivia, additional, Foley, Éimear M., additional, Martin, Brett M., additional, Palmisano, Joseph, additional, Singh, Bhupinder, additional, Green, Katie, additional, Lepage, Christian, additional, Muehlmann, Marc, additional, Makris, Nikos, additional, Cantu, Robert C., additional, Lin, Alexander P., additional, Coleman, Michael, additional, Pasternak, Ofer, additional, Mez, Jesse, additional, Bouix, Sylvain, additional, Shenton, Martha E., additional, and Stern, Robert A., additional

Published
2019
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172. Duration of American Football Play and Chronic Traumatic Encephalopathy

Author

Mez, Jesse, primary, Daneshvar, Daniel H., additional, Abdolmohammadi, Bobak, additional, Chua, Alicia S., additional, Alosco, Michael L., additional, Kiernan, Patrick T., additional, Evers, Laney, additional, Marshall, Laura, additional, Martin, Brett M., additional, Palmisano, Joseph N., additional, Nowinski, Christopher J., additional, Mahar, Ian, additional, Cherry, Jonathan D., additional, Alvarez, Victor E., additional, Dwyer, Brigid, additional, Huber, Bertrand R., additional, Stein, Thor D., additional, Goldstein, Lee E., additional, Katz, Douglas I., additional, Cantu, Robert C., additional, Au, Rhoda, additional, Kowall, Neil W., additional, Stern, Robert A., additional, McClean, Michael D., additional, Weuve, Jennifer, additional, Tripodis, Yorghos, additional, and McKee, Ann C., additional

Published
2019
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173. Association of White Matter Rarefaction, Arteriolosclerosis, and Tau With Dementia in Chronic Traumatic Encephalopathy

Author

Alosco, Michael L., primary, Stein, Thor D., additional, Tripodis, Yorghos, additional, Chua, Alicia S., additional, Kowall, Neil W., additional, Huber, Bertrand Russell, additional, Goldstein, Lee E., additional, Cantu, Robert C., additional, Katz, Douglas I., additional, Palmisano, Joseph N., additional, Martin, Brett, additional, Cherry, Jonathan D., additional, Mahar, Ian, additional, Killiany, Ronald J., additional, McClean, Michael D., additional, Au, Rhoda, additional, Alvarez, Victor, additional, Stern, Robert A., additional, Mez, Jesse, additional, and McKee, Ann C., additional

Published
2019
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175. A magnetic resonance spectroscopy investigation in symptomatic former NFL players

Author

Alosco, Michael L., primary, Tripodis, Yorghos, additional, Rowland, Benjamin, additional, Chua, Alicia S., additional, Liao, Huijun, additional, Martin, Brett, additional, Jarnagin, Johnny, additional, Chaisson, Christine E., additional, Pasternak, Ofer, additional, Karmacharya, Sarina, additional, Koerte, Inga K., additional, Cantu, Robert C., additional, Kowall, Neil W., additional, McKee, Ann C., additional, Shenton, Martha E., additional, Greenwald, Richard, additional, McClean, Michael, additional, Stern, Robert A., additional, and Lin, Alexander, additional

Published
2019
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180. RESPONSE

Author

Cantu, Robert C.

Published
1993

182. Neck trauma: no margin for error

Author

Cantrill, Stephn V., Cantu, Robert C., Ivatury, Rao R., and Viccellio, Peter

Subjects
Neck -- Injuries, Physicians (General practice) -- Practice, Health, Practice, Injuries
Abstract

The neck is crowded with structures vulnerable to serious - and deadly - injury. Blunt neck trauma primarily jeopardizes the seven cervical vertebrae and the spinal cord. A fracture-dislocation that [...]

Published
1994

183. RESPONSE

Author

Cantu, Robert C.

Published
1992

184. SPORTS NEUROLOGY SYMPOSIUM: 1015

Author

Jordan, Barry, Cantu, Robert C., Torg, Joseph S., Micheli, Lyle J., Tsairis, Peter, Alves, Wayne, and Birrer, Richard

Published
1992

187. Consensus statement on concussion in sport—the 5 th international conference on concussion in sport held in Berlin, October 2016

Author

Manley, Geoff T, Tator, Charles H, Echemendia, Ruben J, Nagahiro, Shinji, Aubry, Mark, McCrea, Michael, Engebretsen, Lars, Makdissi, Michael, Davis, Gavin A, Patricios, Jon, Sills, Allen, Bailes, Julian, Cassidy, David, Castellani, Rudy J, Iverson, Grant L, Feddermann-Demont, Nina, Cantu, Robert C, Meeuwisse, Willem, Broglio, Steven, Maddocks, David, Kutcher, Jeffrey, Emery, Carolyn, Herring, Stanley, Putukian, Margot, Guskiewicz, Kevin M, Leddy, John J, Meehan, William P, McCrory, Paul, Dvořák, Jiří, Vos, Pieter E, Giza, Christopher C, Johnston, Karen M, Kissick, James, Schneider, Kathryn J, Turner, Michael, and Ellenbogen, Richard

Abstract

The 2017 Concussion in Sport Group (CISG) consensus statement is designed to build on the principles outlined in the previous statements1–4 and to develop further conceptual understanding of sport-related concussion (SRC) using an expert consensus-based approach. This document is developed for physicians and healthcare providers who are involved in athlete care, whether at a recreational, elite or professional level. While agreement exists on the principal messages conveyed by this document, the authors acknowledge that the science of SRC is evolving and therefore individual management and return-to-play decisions remain in the realm of clinical judgement. This consensus document reflects the current state of knowledge and will need to be modified as new knowledge develops. It provides an overview of issues that may be of importance to healthcare providers involved in the management of SRC. This paper should be read in conjunction with the systematic reviews and methodology paper that accompany it. First and foremost, this document is intended to guide clinical practice; however, the authors feel that it can also help form the agenda for future research relevant to SRC by identifying knowledge gaps.

Published
2017
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193. Acute and chronic effects of exercise using an Exercycle in healthy, untrained adults

Author

Cunningham, Lee N. and Cantu, Robert C.

Subjects
Aerobic exercises -- Health aspects -- Physiological aspects, Vasomotor conditioning -- Evaluation -- Physiological aspects -- Health aspects, Exercise equipment -- Evaluation -- Product/service Evaluations, Exercise bicycles -- Health aspects -- Evaluation -- Product/service Evaluations, Health, Exercycle (Exercise equipment) -- Evaluation
Abstract

L Cunningham, DPE, FASCM, is Professor of Physical Education, Fitchburg State College, 160 Pearl St, Fitchburg, MA 01420-2697 (USA). Address all correspondence to Dr Cunningham. R Cantu, MD, FASCM, is [...]

Published
1990

194. Neck pain in a football player

Author

McKeag, Douglas B. and Cantu, Robert C.

Subjects
Neck pain -- Causes of, Football -- Training, Football -- Wounds and injuries, Health
Abstract

A case history is given of an 18-year-old defensive back (football player) who developed recurrent neck pain on one side after contact during games. He was allowed to continue playing, with no medical intervention. On one occasion, his trainer 'treated' him with the application of force, resulting in increased pain. It is likely, given the young man's position in football and his symptoms, that he had received injury to the cervical spine (the upper portion of the spine), leading to damage of the cervical nerve. Subsequent examination using MRI (magnetic resonance imaging, a technique that allows viewing of the body's soft tissues) confirmed this, showing partial protrusion of two cervical vertebral disks, which are made of fibrous cartilage that separates the vertebral bones. Treatment consisted of stopping football, but this could have been done earlier had medical care been available. Basketball was still allowed, and the patient will return to gymnastics and football. Athletes with such injuries should be made to realize they risk serious injury if they continue to play collision sports. (Consumer Summary produced by Reliance Medical Information, Inc.)

Published
1990

195. Duration of American Football Play and Chronic Traumatic Encephalopathy.

Author

Mez, Jesse, Daneshvar, Daniel H., Abdolmohammadi, Bobak, Chua, Alicia S., Alosco, Michael L., Kiernan, Patrick T., Evers, Laney, Marshall, Laura, Martin, Brett M., Palmisano, Joseph N., Nowinski, Christopher J., Mahar, Ian, Cherry, Jonathan D., Alvarez, Victor E., Dwyer, Brigid, Huber, Bertrand R., Stein, Thor D., Goldstein, Lee E., Katz, Douglas I., and Cantu, Robert C.

Subjects
CHRONIC traumatic encephalopathy, FOOTBALL, RECEIVER operating characteristic curves, CONTACT sports, BRAIN banks, BRAIN, RESEARCH, TIME, RESEARCH methodology, ACQUISITION of data, CASE-control method, EVALUATION research, MEDICAL cooperation, SEVERITY of illness index, COMPARATIVE studies, BLIND experiment, RESEARCH funding
Abstract

Objective: Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with exposure to contact and collision sports, including American football. We hypothesized a dose-response relationship between duration of football played and CTE risk and severity.Methods: In a convenience sample of 266 deceased American football players from the Veterans Affairs-Boston University-Concussion Legacy Foundation and Framingham Heart Study Brain Banks, we estimated the association of years of football played with CTE pathological status and severity. We evaluated the ability of years played to classify CTE status using receiver operating characteristic curve analysis. Simulation analyses quantified conditions that might lead to selection bias.Results: In total, 223 of 266 participants met neuropathological diagnostic criteria for CTE. More years of football played were associated with having CTE (odds ratio [OR] = 1.30 per year played, 95% confidence interval [CI] = 1.19-1.41; p = 3.8 × 10-9 ) and with CTE severity (severe vs mild; OR = 1.14 per year played, 95% CI = 1.07-1.22; p = 3.1 × 10-4 ). Participants with CTE were 1/10th as likely to have played <4.5 years (negative likelihood ratio [LR] = 0.102, 95% CI = 0.100-0.105) and were 10 times as likely to have played >14.5 years (positive LR = 10.2, 95% CI = 9.8-10.7) compared with participants without CTE. Sensitivity and specificity were maximized at 11 years played. Simulation demonstrated that years played remained adversely associated with CTE status when years played and CTE status were both related to brain bank selection across widely ranging scenarios.Interpretation: The odds of CTE double every 2.6 years of football played. After accounting for brain bank selection, the magnitude of the relationship between years played and CTE status remained consistent. ANN NEUROL 2020;87:116-131. [ABSTRACT FROM AUTHOR]

Published
2020
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197. Concussion management in combat sports: consensus statement from the Association of Ringside Physicians

Author

Neidecker, John, primary, Sethi, Nitin K, additional, Taylor, Randolph, additional, Monsell, Raymond, additional, Muzzi, Don, additional, Spizler, Bruce, additional, Lovelace, Larry, additional, Ayoub, Edmund, additional, Weinstein, Rick, additional, Estwanik, Joseph, additional, Reyes, Patricio, additional, Cantu, Robert C, additional, Jordan, Barry, additional, Goodman, Margaret, additional, Stiller, John W, additional, Gelber, Jonathan, additional, Boltuch, Robert, additional, Coletta, Domenic, additional, Gagliardi, Angela, additional, Gelfman, Stephen, additional, Golden, Patrick, additional, Rizzo, Nicholas, additional, Wallace, Paul, additional, Fields, Allan, additional, and Inalsingh, Calvin, additional

Published
2018
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198. Lewy Body Pathology and Chronic Traumatic Encephalopathy Associated With Contact Sports

Author

Adams, Jason W, primary, Alvarez, Victor E, additional, Mez, Jesse, additional, Huber, Bertrand R, additional, Tripodis, Yorghos, additional, Xia, Weiming, additional, Meng, Gaoyuan, additional, Kubilus, Caroline A, additional, Cormier, Kerry, additional, Kiernan, Patrick T, additional, Daneshvar, Daniel H, additional, Chua, Alicia S, additional, Svirsky, Sarah, additional, Nicks, Raymond, additional, Abdolmohammadi, Bobak, additional, Evers, Laney, additional, Solomon, Todd M, additional, Cherry, Jonathan D, additional, Aytan, Nurgul, additional, Mahar, Ian, additional, Devine, Sherral, additional, Auerbach, Sanford, additional, Alosco, Michael L, additional, Nowinski, Christopher J, additional, Kowall, Neil W, additional, Goldstein, Lee E, additional, Dwyer, Brigid, additional, Katz, Douglas I, additional, Cantu, Robert C, additional, Stern, Robert A, additional, Au, Rhoda, additional, McKee, Ann C, additional, and Stein, Thor D, additional

Published
2018
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199. Age of first exposure to tackle football and chronic traumatic encephalopathy

Author

Alosco, Michael L., primary, Mez, Jesse, additional, Tripodis, Yorghos, additional, Kiernan, Patrick T., additional, Abdolmohammadi, Bobak, additional, Murphy, Lauren, additional, Kowall, Neil W., additional, Stein, Thor D., additional, Huber, Bertrand Russell, additional, Goldstein, Lee E., additional, Cantu, Robert C., additional, Katz, Douglas I., additional, Chaisson, Christine E., additional, Martin, Brett, additional, Solomon, Todd M., additional, McClean, Michael D., additional, Daneshvar, Daniel H., additional, Nowinski, Christopher J., additional, Stern, Robert A., additional, and McKee, Ann C., additional

Published
2018
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