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155. Indirect Method Usage of Distance and Error Measurement by Single Optical Cameras.

Author

Bui, M. Tuan, Doskocil, R., Krivanek, V., Ha, T. Hien, Bergeon, Y., and Kutilek, P.

Subjects
*DISTANCE measurement equipment, *CAMERAS, *TRIANGULATION, *MEASUREMENT errors, *AGGREGATION (Robotics)
Abstract

In this paper, we proposed an indirect method to measure the distance of an object accurately by single visual cameras using triangulation. The object can be seen as the third point of a triangle with two known sides and one known angle. Distance to object can be determined indirectly on the base of known sides and angle, rather than being measured directly. It would be very useful in case there is no line of sight to object (inaccessible) or an obstacle interrupts it. Furthermore, the results show that the measured distance using the indirect method has a lower measurement error than the one using the direct method. This method establishes a basis for the implementation of the position algorithm into the navigation subsystem of swarm robots and will be very helpful especially in robot cooperation. [ABSTRACT FROM AUTHOR]

Published
2018
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156. Population-based cohort study of oral contraceptive use and risk of depression

Author

Johansson, T., Vinther Larsen, S., Bui, M., Ek, W. E., Karlsson, T., and Johansson, Å.

Abstract

AbstractAimResearch on the effect of oral contraceptive (OC) use on the risk of depression shows inconsistent findings, especially in adult OC users. One possible reason for this inconsistency is the omission of women who discontinue OCs due to adverse mood effects, leading to healthy user bias. To address this issue, we aim to estimate the risk of depression that is associated with the initiation of OCs as well as the effect of OC use on lifetime risk of depression.MethodsThis is a population-based cohort study based on data from 264,557 women from the UK Biobank. Incidence of depression was addressed via interviews, inpatient hospital or primary care data. The hazard ratio (HR) between OC use and incident depression was estimated by multivariable Cox regression with OC use as a time-varying exposure. To validate causality, we examined familial confounding in 7,354 sibling pairs.ResultsWe observed that the first 2 years of OC use were associated with a higher rate of depression compared to never users (HR = 1.71, 95% confidence interval [CI]: 1.55–1.88). Although the risk was not as pronounced beyond the first 2 years, ever OC use was still associated with an increased lifetime risk of depression (HR = 1.05, 95% CI: 1.01–1.09). Previous OC use were associated with a higher rate of depression compared to never users, with adolescent OC users driving the increased hazard (HR = 1.18, 95% CI: 1.12–1.25). No significant association were observed among adult OC users who had previously used OCs (HR = 1.00, 95% CI: 0.95–1.04). Notably, the sibling analysis provided further evidence for a causal effect of OC use on the risk of depression.ConclusionsOur findings suggest that the use of OCs, particularly during the first 2 years, increases the risk of depression. Additionally, OC use during adolescence might increase the risk of depression later in life. Our results are consistent with a causal relationship between OC use and depression, as supported by the sibling analysis. This study highlights the importance of considering the healthy user bias as well as family-level confounding in studies of OC use and mental health outcomes. Physicians and patients should be aware of this potential risk when considering OCs, and individualized risk–benefit assessments should be conducted.

Published
2024
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157. Ethnicity and age disparties in ewing sarcoma outcome

Author

KOOHBANANI B, HAN G, REED D, HENDERSON E, YI D, BUI M. M., RUGGIERI, PIETRO, KOOHBANANI B, HAN G, REED D, HENDERSON E, YI D, RUGGIERI P, and BUI M M

Subjects
age, ewing sarcoma, outcome
Abstract

Ethnicity and age disparties in ewing sarcoma outcome

Published
2012

158. Well differentiated liposarcomas/ atipical lipomatous tumors of the extremities

Author

Cheong, D, Bui, M. M., Gonzales, R. J., Buchanan, Pala, E, Romagnoli, C, Letson, D, Ruggieri, Pietro, CHEONG D, BUI M M, GONZALES R. J, BUCHANAN, PALA E, ROMAGNOLI C, LETSON D, and RUGGIERI P

Subjects
tumors, tumor, extremities, liposarcoma
Abstract

Well differentiated liposarcomas/ atipical lipomatous tumors of the extremities

Published
2012

160. Aetiological overlap between obsessive-compulsive related and anxiety disorder symptoms: multivariate twin study

Author

Lopez-Sola, C, Fontenelle, LF, Bui, M, Hopper, JL, Pantelis, C, Yuecel, M, Menchon, JM, Alonso, P, Harrison, BJ, Lopez-Sola, C, Fontenelle, LF, Bui, M, Hopper, JL, Pantelis, C, Yuecel, M, Menchon, JM, Alonso, P, and Harrison, BJ

Abstract

BACKGROUND: The aetiological boundary between obsessive-compulsive related disorders (OCRDs) including obsessive-compulsive disorder (OCD) and anxiety disorders is unclear and continues to generate debate. AIMS: To determine the genetic overlap and the pattern of causal relationships among OCRDs and anxiety disorders. METHOD: Multivariate twin modelling methods and a new regression analysis to infer causation were used, involving 2495 male and female twins. RESULTS: The amount of common genetic liability observed for OCD symptoms was higher when considering anxiety disorders and OCRDs in the model v. modelling OCRD symptoms alone. OCD symptoms emerged as risk factors for the presence of generalised anxiety, panic and hoarding symptoms, whereas social phobia appeared as a risk factor for OCD symptoms. CONCLUSIONS: OCD represents a complex phenotype that includes important shared features with anxiety disorders and OCRDs. The novel patterns of risk identified between OCD and anxiety disorder may help to explain their frequent co-occurrence.

Published
2016

161. Childhood body mass index and adult mammographic density measures that predict breast cancer risk

Author

Hopper, JL, Nguyen, TL, Stone, J, Aujard, K, Matheson, MC, Abramson, MJ, Burgess, JA, Walters, EH, Dite, GS, Bui, M, Evans, C, Makalic, E, Schmidt, DF, Ward, G, Jenkins, MA, Giles, GG, Dharmage, SC, Apicella, C, Hopper, JL, Nguyen, TL, Stone, J, Aujard, K, Matheson, MC, Abramson, MJ, Burgess, JA, Walters, EH, Dite, GS, Bui, M, Evans, C, Makalic, E, Schmidt, DF, Ward, G, Jenkins, MA, Giles, GG, Dharmage, SC, and Apicella, C

Abstract

The aim of the present study is to determine if body mass index (BMI) during childhood is associated with the breast cancer risk factor 'adult mammographic density adjusted for age and BMI'. In 1968, the Tasmanian Longitudinal Health Study studied every Tasmanian school child born in 1961. We obtained measured heights and weights from annual school medical records across ages 7-15 years and imputed missing values. Between 2009 and 2012, we administered to 490 women a questionnaire that asked current height and weight and digitised at least one mammogram per woman. Absolute and percent mammographic densities were measured using the computer-assisted method CUMULUS. We used linear regression and adjusted for age at interview and log current BMI. The mammographic density measures were negatively associated: with log BMI at each age from 7 to 15 years (all p < 0.05); with the average of standardised log BMIs across ages 7-15 years (p < 0.0005); and more strongly with standardised log BMI measures closer to age 15 years (p < 0.03). Childhood BMI measures explained 7 and 10 % of the variance in absolute and percent mammographic densities, respectively, and 25 and 20 % of the association between current BMI and absolute and percent mammographic densities, respectively. Associations were not altered by adjustment for age at menarche. There is a negative association between BMI in late childhood and the adult mammographic density measures that predict breast cancer risk. This could explain, at least in part, why BMI in adolescence is negatively associated with breast cancer risk.

Published
2016

162. Mutations in a novel GTPase cause autosomal dominant hereditary spastic paraplegia

Author

Zhao, X., Alvarado, D., Rainier, S., Lemons, R., Hedera, P., Weber, C., Tukel, T., Apak, M., Heiman-Patterson, T., Ming, L., Bui, M., and Fink, J.K.

Subjects
Human genetics -- Research, Gene mutations -- Physiological aspects, Genetic disorders -- Physiological aspects, Spasticity -- Genetic aspects, Biological sciences
Published
2001

164. MicroRNA related polymorphisms and breast cancer risk

Author

Khan, S., Greco, D., Michailidou, K., Milne, R.L., Muranen, T.A., Heikkinen, T., Aaltonen, K., Dennis, J., Bolla, M.K., Liu, J., Hall, P., Irwanto, A., Humphreys, K., Li, J., Czene, K., Chang-Claude, J., Hein, R., Rudolph, A., Seibold, P., Flesch-Janys, D., Fletcher, O., Peto, J., Silva, I.D., Johnson, N., Gibson, L., Aitken, Z., Hopper, J.L., Tsimiklis, H., Bui, M., Makalic, E., Schmidt, D.F., Southey, M.C., Apicella, C., Stone, J., Waisfisz, Q., Meijers-Heijboer, H., Adank, M.A., Luijt, R.B. van der, Meindl, A., Schmutzler, R.K., Muller-Myhsok, B., Lichtner, P., Turnbull, C., Rahman, N., Chanock, S.J., Hunter, D.J., Cox, A., Cross, S.S., Reed, M.W.R., Schmidt, M.K., Broeks, A., Van't Veer, L.J., Hogervorst, F.B., Fasching, P.A., Schrauder, M.G., Ekici, A.B., Beckmann, M.W., Bojesen, S.E., Nordestgaard, B.G., Nielsen, S.F., Flyger, H., Benitez, J., Zamora, P.M., Perez, J.I.A., Haiman, C.A., Henderson, B.E., Schumacher, F., Marchand, L. le, Pharoah, P.D.P., Dunning, A.M., Shah, M., Luben, R., Brown, J., Couch, F.J., Wang, X., Vachon, C., Olson, J.E., Lambrechts, D., Moisse, M., Paridaens, R., Christiaens, M.R., Guenel, P., Truong, T., Laurent-Puig, P., Mulot, C., Marme, F., Burwinkel, B., Schneeweiss, A., Sohn, C., Sawyer, E.J., Tomlinson, I., Kerin, M.J., Miller, N., Andrulis, I.L., Knight, J.A., Tchatchou, S., Mulligan, A.M., Dork, T., Bogdanova, N.V., Antonenkova, N.N., Anton-Culver, H., Darabi, H., Eriksson, M., Garcia-Closas, M., Figueroa, J., Lissowska, J., Brinton, L., Devilee, P., Tollenaar, R.A.E.M., Seynaeve, C., Asperen, C.J. van, Kristensen, V.N., Slager, S., Toland, A.E., Ambrosone, C.B., Yannoukakos, D., Lindblom, A., Margolin, S., Radice, P., Peterlongo, P., Barile, M., Mariani, P., Hooning, M.J., Martens, J.W.M., Collee, J.M., Jager, A., Jakubowska, A., Lubinski, J., Jaworska-Bieniek, K., Durda, K., Giles, G.G., McLean, C., Brauch, H., Bruning, T., Ko, Y.D., Brenner, H., Dieffenbach, A.K., Arndt, V., Stegmaier, C., Swerdlow, A., Ashworth, A., Orr, N., Jones, M., Simard, J., Goldberg, M.S., Labreche, F., Dumont, M., Winqvist, R., Pylkas, K., Jukkola-Vuorinen, A., Grip, M., Kataja, V., Kosma, V.M., Hartikainen, J.M., Mannermaa, A., Hamann, U., Chenevix-Trench, G., Blomqvist, C., Aittomaki, K., Easton, D.F., Nevanlinna, H., KConFab Investigators, Australian Ovarian Canc Study Grp, GENICA Network, Department of Obstetrics and Gynecology, Clinicum, Department of Oncology, Haartman Institute (-2014), Department of Medical and Clinical Genetics, HUS Gynecology and Obstetrics, Human genetics, CCA - Oncogenesis, Obstetrics & Gynecology, Medical Oncology, Erasmus MC other, and Clinical Genetics

Subjects
Heredity, IDENTIFIES 3, lcsh:Medicine, Estrogen receptor, Genome-wide association study, Bioinformatics, 3123 Gynaecology and paediatrics, HUMAN GENES, lcsh:Science, 3' Untranslated Regions, Multidisciplinary, Research Support, Non-U.S. Gov't, Chromosome Mapping, SINGLE-NUCLEOTIDE POLYMORPHISMS, 3. Good health, Receptors, Estrogen, Female, CASP8 GENE, Research Article, EXPRESSION, Genotype, SUSCEPTIBILITY LOCI, education, 3122 Cancers, MiRNA binding, Single-nucleotide polymorphism, Breast Neoplasms, Biology, Genetic Predisposition, Polymorphism, Single Nucleotide, BINDING-SITES, Breast cancer, REDUCED RISK, Research Support, N.I.H., Extramural, SDG 3 - Good Health and Well-being, microRNA, Genetic predisposition, medicine, Journal Article, Genetics, Cancer Genetics, Humans, GENOME-WIDE ASSOCIATION, Drosha, Genetic Association Studies, Binding Sites, Complex Traits, lcsh:R, Biology and Life Sciences, Computational Biology, Human Genetics, medicine.disease, Research Support, N.I.H., Intramural, COMMON VARIANT, MicroRNAs, Case-Control Studies, Genetics of Disease, lcsh:Q, Research Support, U.S. Gov't, Non-P.H.S, Genome-Wide Association Study
Abstract

Genetic variations, such as single nucleotide polymorphisms (SNPs) in microRNAs (miRNA) or in the miRNA binding sites may affect the miRNA dependent gene expression regulation, which has been implicated in various cancers, including breast cancer, and may alter individual susceptibility to cancer. We investigated associations between miRNA related SNPs and breast cancer risk. First we evaluated 2,196 SNPs in a case-control study combining nine genome wide association studies (GWAS). Second, we further investigated 42 SNPs with suggestive evidence for association using 41,785 cases and 41,880 controls from 41 studies included in the Breast Cancer Association Consortium (BCAC). Combining the GWAS and BCAC data within a meta-analysis, we estimated main effects on breast cancer risk as well as risks for estrogen receptor (ER) and age defined subgroups. Five miRNA binding site SNPs associated significantly with breast cancer risk: rs1045494 (odds ratio (OR) 0.92; 95 confidence interval (CI): 0.88-0.96), rs1052532 (OR 0.97; 95 CI: 0.95-0.99), rs10719 (OR 0.97; 95 Cl: 0.94-0.99), rs4687554 (OR 0.97; 95 CI: 0.95-0.99, and rs3134615 (OR 1.03; 95 CI: 1.01 -1.05) located in the 3' UTR of CASP8, HDDC3, DROSHA, MUSTN1, and MYCL1, respectively. DROSHA belongs to miRNA machinery genes and has a central role in initial miRNA processing. The remaining genes are involved in different molecular functions, including apoptosis and gene expression regulation. Further studies are warranted to elucidate whether the miRNA binding site SNPs are the causative variants for the observed risk effects. This is an open-access article free of all copyright.

Published
2014

169. Psychological status in female carriers of premutation FMR1 allele showing a complex relationship with the size of CGG expansion.

Author

Loesch, D, Loesch, D, Bui, M, Hammersley, E, Schneider, A, Storey, E, Stimpson, P, Burgess, T, Francis, D, Slater, H, Tassone, Flora, Hagerman, Randi, Hessl, David, Loesch, D, Loesch, D, Bui, M, Hammersley, E, Schneider, A, Storey, E, Stimpson, P, Burgess, T, Francis, D, Slater, H, Tassone, Flora, Hagerman, Randi, and Hessl, David

Abstract

We utilized a sample of 299 adult females aged between 19 and 86 years, carrying fragile X mental retardation (FMR1) alleles with small CCG expansions ranging from 50 to 141 repeats to analyse the relationships between psychological symptoms as assessed by the Symptom Checklist-90-Revised (SCL-90-R) and the size of the CGG repeat in the FMR1 gene. There were highly significant (negative) correlations between the size of the CGG repeat and a great majority of SCL-90-R subscale scores and all the global indices, suggesting that carriers of premutations in the mid-size CGG repeat range may be at greatest risk for the development of psychiatric disorder.

Published
2015

170. Foreword

Author

De Raedt, Luc, Deville, Y, Bui, M, Truong, D. L., Quyet, T. H., Le, A. P., De Raedt, Luc, Deville, Y, Bui, M, Truong, D. L., Quyet, T. H., and Le, A. P.

Abstract

The Sixth International Symposium on Information and Communication Technology (SoICT 2015), Hue City, Vietnam December 3-4, 2015

Published
2015

174. FIB plan view lift-out sample preparation for TEM characterization of periodic nanostructures obtained by spinodal decomposition in Co1.7Fe1.3O4 thin films.

Author

Dinh, T. M. C., Barnabé, A., Bui, M. A., Josse, C., Hungria, T., Bonningue, C., Presmanes, L., and Tailhades, P.

Subjects
NANOSTRUCTURES, COBALT compounds, TRANSMISSION electron microscopy
Abstract

There is a miscibility gap in the CoFe2O4–Co3O4 phase diagram. In this miscibility gap, the oxides can be subjected to a spinodal transformation. It has already been observed in oxides consisting of crystals greater than or equal to 100 nm that spinodal decomposition leads to the formation of two alternating iron-rich and cobalt-rich spinel phases. The pseudo-periodic alternation occurs approximately every 5 nm. In the miscibility gap, thin films of pure iron cobaltites, consisting of crystallites of the order of 10 nm in diameter and around 300 nm in thickness, undergo transformation when they are treated at 600 °C for several hours. X-ray diffraction and Raman spectroscopy clearly reveal this transformation, which is accentuated as a function of the treatment time. An electron microscopy study of the cross-sections (view of the films along their thickness), confirms the progressive separation of the former spinel oxide in iron-rich and cobalt-rich spinel phases, without however revealing a pseudo-periodic organization of these phases, whatever the time of treatment. In an attempt to reveal this organization, a specific method of preparation has been implemented to extract the upper part of the films parallel to their basic plane and to observe the crystallites in plan view. The alternation of the iron- and cobalt-rich phases could, however, only be found in the largest crystallites. It seems that the nanometric size of the crystallites prevents the establishment of a pseudo-periodic organization of the phases during the periodic transformation. The observation of compositional anomalies in the grain boundaries seems to support the hypothesis related to a nanometric effect of the crystallization. [ABSTRACT FROM AUTHOR]

Published
2018
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175. Water temperatures in the headwaters of the Volga River: Trend analyses, possible future changes, and implications for a pan‐European perspective.

Author

Seidel, J., Bui, M. T., Kuzovlev, V. V., Zhenikov, Y. N., Füreder, L., and Schletterer, M.

Subjects
WATER temperature, DATA analysis, ECOSYSTEMS, CLIMATE change, STOCHASTIC models
Abstract

Abstract: Water temperature is a physical property influencing abiotic and biotic parameters in an aquatic ecosystem. In different Central European rivers and lakes, a general trend of water temperatures in the range of +0.05 to +0.8 °C per decade was identified. Our case study analyses whether similar patterns apply to the headwaters of the Volga River, in the East European plain. Based on a dataset of water temperatures for 2008–2015, we investigated the spatial and temporal distribution of water temperature along the Tudovka River and estimated backward as well as predicted future changes from development scenarios throughout the 21st century. Stochastic models were applied to track trends and variations in water temperature. Furthermore, the correlation between water temperature and air temperatures was used to model historical water temperatures and to predict possible changes in the future, under the effects of climate change. Based on climate change scenarios, an increase of the mean water temperatures as well as changes regarding the ice cover can be expected until the end of this century. The conditions described for the headwaters of the Volga River system represent a valuable dataset for medium and large rivers in the East European plain and serve as a basis for future management. [ABSTRACT FROM AUTHOR]

Published
2018
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176. Complex System Approach in Modeling Airspace Congestion Dynamics

Author

Amor S., Ben, Bui, M., Cognitions Humaine et ARTificielle (CHART), École pratique des hautes études (EPHE)-Université Paris 8 Vincennes-Saint-Denis (UP8)-Université Paris Nanterre (UPN)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Laboratoire d'informatique et des systèmes complexes (LAISC), École pratique des hautes études (EPHE), Université Paris 8 Vincennes-Saint-Denis (UP8)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Nanterre (UPN)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), Tijus, Charles, and Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Université Paris Nanterre (UPN)-Université Paris 8 Vincennes-Saint-Denis (UP8)-École pratique des hautes études (EPHE)

Subjects
[SHS.INFO]Humanities and Social Sciences/Library and information sciences, [SHS.INFO] Humanities and Social Sciences/Library and information sciences
Published
2012

177. Genome-wide association analysis identifies three new breast cancer susceptibility loci

Author

Ghoussaini, M, Fletcher, O, Michailidou, K, Turnbull, C, Schmidt, MK, Dicks, E, Dennis, J, Wang, Q, Humphreys, MK, Luccarini, C, Baynes, C, Conroy, D, Maranian, M, Ahmed, S, Driver, K, Johnson, N, Orr, N, Dos Santos Silva, I, Waisfisz, Q, Meijers-Heijboer, H, Uitterlinden, AG, Rivadeneira, F, Hall, P, Czene, K, Irwanto, A, Liu, J, Nevanlinna, H, Aittom Currency Signki, K, Blomqvist, C, Meindl, A, Schmutzler, RK, Müller-Myhsok, B, Lichtner, P, Chang-Claude, J, Hein, R, Nickels, S, Flesch-Janys, D, Tsimiklis, H, Makalic, E, Schmidt, D, Bui, M, Hopper, JL, Apicella, C, Park, DJ, Southey, M, Hunter, DJ, Chanock, SJ, Broeks, A, Verhoef, S, Hogervorst, FBL, Fasching, PA, Lux, MP, Beckmann, MW, Ekici, AB, Sawyer, E, Tomlinson, I, Kerin, M, Marme, F, Schneeweiss, A, Sohn, C, Burwinkel, B, Guénel, P, Truong, T, Cordina-Duverger, E, Menegaux, F, Bojesen, SE, Nordestgaard, BG, Nielsen, SF, Flyger, H, Milne, RL, Alonso, MR, Gonzlez-Neira, A, Ben-tez, J, Anton-Culver, H, Ziogas, A, Bernstein, L, Dur, CC, Brenner, H, Müller, H, Arndt, V, Stegmaier, C, Justenhoven, C, and Brauch, H

Abstract

Breast cancer is the most common cancer among women. To date, 22 common breast cancer susceptibility loci have been identified accounting for g1/48% of the heritability of the disease. We attempted to replicate 72 promising associations from two independent genome-wide association studies (GWAS) in g1/470,000 cases and ĝ̂1/468,000 controls from 41 case-control studies and 9 breast cancer GWAS. We identified three new breast cancer risk loci at 12p11 (rs10771399; P = 2.7 - 10 g35), 12q24 (rs1292011; P = 4.3 - 10 g19) and 21q21 (rs2823093; P = 1.1 - 10 g12). rs10771399 was associated with similar relative risks for both estrogen receptor (ER)-negative and ER-positive breast cancer, whereas the other two loci were associated only with ER-positive disease. Two of the loci lie in regions that contain strong plausible candidate genes: PTHLH (12p11) has a crucial role in mammary gland development and the establishment of bone metastasis in breast cancer, and NRIP1 (21q21) encodes an ER cofactor and has a role in the regulation of breast cancer cell growth. © 2012 Nature America, Inc. All rights reserved.

Published
2012

178. Un outil de navigation dans un espace sémantique

Author

Hoareau, Y., Ahat, Murat, Medernach, D., Bui, M., Cognitions Humaine et ARTificielle (CHART), École pratique des hautes études (EPHE)-Université Paris 8 Vincennes-Saint-Denis (UP8)-Université Paris Nanterre (UPN)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Laboratoire d'informatique et des systèmes complexes (LAISC), École pratique des hautes études (EPHE), Université Paris 8 Vincennes-Saint-Denis (UP8)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Nanterre (UPN)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), and Tijus, Charles

Subjects
ComputingMilieux_MISCELLANEOUS
Abstract

National audience

Published
2011

179. Oblique Angle of Incidence Measurement of PV Modules on a Solar Simulator

Author

Bui, M., Völker, C., Li, B., and Doble, D.M.J.

Subjects
PV Modules, Components for PV Systems
Abstract

26th European Photovoltaic Solar Energy Conference and Exhibition; 3476-3479, Evaluating the performance of photovoltaic (PV) modules at oblique angle of incidence (AOI) is important for accurate energy yield prediction. The AOI effect has been investigated based on outdoor measurement and the following optical model simulation. The advantage of indoor over outdoor conditions is that irradiance, AOI, and module temperature can be well defined, while a major challenge is the spatial non-uniformity of irradiance when the module is tilted. The work presented herein concerns a multi-step approach that enables the prediction of module performance in the field at varying AOI using an indoor solar simulator. A class AAA solar simulator and a custom-designed module holder with bearings for tilting have been used for this study. The first step involves mapping out the spatial non-uniformities of irradiance at different AOI by collecting measurements for a reference cell at multiple points across the inclined plane. The I-V characteristics of the module were then measured in tilted configurations. The resulting I-V curve for a standard module with six rows of cells exhibited three platforms corresponding to the three different short-circuit currents generated each of the three strings. It was also found that AOI measurements could be used to determine which contains the current-limiting cell. This was accomplished through flipping the module left to right and repeating the I-V measurement at oblique AOI. Since the uppermost row receives less light than the lower row in a given string, the Isc of the individual string is always determined by the worst cell in the top row. Finally, the position of the monitor cell was adjusted to regulate the total amount of illumination to ensure 1000 W/m2 on one single string at different AOI for I-V measurement. Assuming that the quantum efficiency is uniform across the cell, such I-V characteristics are representative of the module performance in the field.

Published
2011
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183. Modeling urban aerial pollution

Author

Benamor, S., Bui, M., Lamure, M., Cognitions Humaine et ARTificielle (CHART), Université Paris 8 Vincennes-Saint-Denis (UP8)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Nanterre (UPN)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Laboratoire d'informatique et des systèmes complexes (LAISC), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), Tijus, Charles, École pratique des hautes études (EPHE)-Université Paris 8 Vincennes-Saint-Denis (UP8)-Université Paris Nanterre (UPN)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), and Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Université Paris Nanterre (UPN)-Université Paris 8 Vincennes-Saint-Denis (UP8)-École pratique des hautes études (EPHE)

Subjects
[MATH.MATH-GM]Mathematics [math]/General Mathematics [math.GM], [SHS.INFO]Humanities and Social Sciences/Library and information sciences, [MATH.MATH-GM] Mathematics [math]/General Mathematics [math.GM], [SHS.INFO] Humanities and Social Sciences/Library and information sciences
Published
2010

184. Document Classification with LSA and Pretopology

Author

Ahat, Murat, Amor S., Ben, Bui, M., Jhean-Larose, Sandra, Denhiere, G., Tijus, Charles, Cognitions Humaine et ARTificielle (CHART), Université Paris 8 Vincennes-Saint-Denis (UP8)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Nanterre (UPN)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Laboratoire d'informatique et des systèmes complexes (LAISC), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), École pratique des hautes études (EPHE)-Université Paris 8 Vincennes-Saint-Denis (UP8)-Université Paris Nanterre (UPN)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), and Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Université Paris Nanterre (UPN)-Université Paris 8 Vincennes-Saint-Denis (UP8)-École pratique des hautes études (EPHE)

Subjects
[SHS.INFO]Humanities and Social Sciences/Library and information sciences, [SHS.INFO] Humanities and Social Sciences/Library and information sciences
Published
2010

185. LSA analysis and visualization with pretopology

Author

Ahat, Murat, Amor S., Ben, Bui, M., Jhean-Larose, Sandra, Denhière, G., Cognitions Humaine et ARTificielle (CHART), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Université Paris Nanterre (UPN)-Université Paris 8 Vincennes-Saint-Denis (UP8)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), Laboratoire d'informatique et des systèmes complexes (LAISC), École pratique des hautes études (EPHE), École pratique des hautes études (EPHE)-Université Paris 8 Vincennes-Saint-Denis (UP8)-Université Paris Nanterre (UPN)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Université Paris 8 Vincennes-Saint-Denis (UP8)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Nanterre (UPN)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), and Tijus, Charles

Subjects
[SHS.INFO]Humanities and Social Sciences/Library and information sciences, [SHS.INFO] Humanities and Social Sciences/Library and information sciences
Published
2010

186. MicroRNA related polymorphisms and breast cancer risk

Author

Khan, S. (Sofia), Greco, D. (Dario), Michailidou, K. (Kyriaki), Milne, R.L. (Roger), Muranen, T.A. (Taru), Heikkinen, T. (Tuomas), Aaltonen, K. (Kirsimari), Dennis, J. (Joe), Bolla, M.K. (Manjeet), Liu, J. (Jianjun), Hall, P. (Per), Irwanto, A. (Astrid), Humphreys, M.K. (Manjeet), Li, J. (Jingmei), Czene, K. (Kamila), Chang-Claude, J. (Jenny), Hein, R. (Rebecca), Rudolph, A. (Anja), Seibold, P. (Petra), Flesch-Janys, D. (Dieter), Fletcher, O. (Olivia), Peto, J. (Julian), Santos Silva, I. (Isabel) dos, Johnson, N. (Nichola), Gibson, L.J. (Lorna), Aitken, Z. (Zoe), Hopper, J.L. (John), Tsimiklis, H. (Helen), Bui, M. (Minh), Makalic, E. (Enes), Schmidt, D.F. (Daniel), Southey, M.C. (Melissa), Apicella, C. (Carmel), Stone, J. (Jennifer), Waisfisz, Q. (Quinten), Meijers-Heijboer, E.J. (Hanne), Adank, M.A. (Muriel), Luijt, R.B. (Rob) van der, Meindl, A. (Alfons), Schmutzler, R.K. (Rita), Müller-Myhsok, B. (B.), Lichtner, P. (Peter), Turnbull, C. (Clare), Rahman, N. (Nazneen), Chanock, S.J. (Stephen), Hunter, D. (David), Cox, A. (Angela), Cross, S.S. (Simon), Reed, M.W.R. (Malcolm), Schmidt, M.K. (Marjanka), Broeks, A. (Annegien), Veer, L.J. (Laura) van 't, Hogervorst, F.B.L. (Frans), Fasching, P.A. (Peter), Schrauder, A. (André), Ekici, A.B. (Arif), Beckmann, M.W. (Matthias), Bojesen, S.E. (Stig), Nordestgaard, B.G. (Børge), Nielsen, S.F. (Sune), Flyger, H. (Henrik), Benítez, J. (Javier), Zamora, P.M. (Pilar M.), Perez, J.I.A. (Jose Ignacio Arias), Haiman, C.A. (Christopher), Henderson, B.E. (Brian), Schumacher, F.R. (Fredrick), March, L.L. (Loic Le), Pharoah, P.D.P. (Paul), Dunning, A.M. (Alison), Shah, M. (Mitul), Luben, R.N. (Robert), Brown, J. (Judith), Couch, F.J. (Fergus), Wang, X. (X.), Vachon, C. (Celine), Olson, J.E. (Janet), Lambrechts, D. (Diether), Moisse, M. (Matthieu), Paridaens, R. (Robert), Christiaens, M.R. (Marie Rose), Guénel, P. (Pascal), Truong, T. (Thérèse), Laurent-Puig, P. (Pierre), Mulot, C. (Claire), Marme, F. (Frederick), Burwinkel, B. (Barbara), Schneeweiss, A. (Andreas), Sohn, C. (Christof), Sawyer, E.J. (Elinor), Tomlinson, I.P. (Ian), Kerin, M. (Michael), Miller, N. (Nicola), Andrulis, I.L. (Irene), Knight, J.A. (Julia), Tchatchou, S. (Srine), Mulligan, A.-M. (Anna-Marie), Dörk, T. (Thilo), Bogdanova, N.V. (Natalia), Antonenkova, N.N. (Natalia), Anton-Culver, H. (Hoda), Darabi, H. (Hatef), Eriksson, M. (Mats), García-Closas, M. (Montserrat), Figueroa, J.D. (Jonine), Lissowska, J. (Jolanta), Brinton, L.A. (Louise), Devilee, P. (Peter), Tollenaar, R.A.E.M. (Rob), Seynaeve, C.M. (Caroline), Asperen, C.J. (Christi) van, Kristensen, V. (Vessela), Slager, S. (Susan), Tol, A.E. (Ama E.), Ambrosone, C.B. (Christine), Yannoukakos, D. (Drakoulis), Lindblom, A. (Annika), Margolin, S. (Sara), Radice, P. (Paolo), Peterlongo, P. (Paolo), Barile, M. (Monica), Mariani, P. (Paolo), Hooning, M.J. (Maartje), Martens, J.W.M. (John), Collée, J.M. (Margriet), Jager, A. (Agnes), Jakubowska, A. (Anna), Lubinski, J. (Jan), Jaworska-Bieniek, K. (Katarzyna), Durda, K. (Katarzyna), Giles, G.G. (Graham), McLean, C.A. (Catriona Ann), Brauch, H. (Hiltrud), Brüning, T. (Thomas), Ko, Y.-D. (Yon-Dschun), Brenner, H. (Hermann), Dieffenbach, A.K. (Aida Karina), Arndt, V. (Volker), Stegmaier, C. (Christa), Swerdlow, A.J. (Anthony ), Ashworth, A. (Alan), Orr, N. (Nick), Jones, M. (Michael), Simard, J. (Jacques), Goldberg, M.S. (Mark), Labrèche, F. (France), Dumont, M. (Martine), Winqvist, R. (Robert), Pykäs, K. (Katri), Jukkola-Vuorinen, A. (Arja), Grip, M. (Mervi), Kataja, V. (Vesa), Kosma, V-M. (Veli-Matti), Hartikainen, J.M. (J.), Mannermaa, A. (Arto), Hamann, U. (Ute), Chenevix-Trench, G. (Georgia), Blomqvist, C. (Carl), Aittomäki, K. (Kristiina), Easton, D.F. (Douglas), Nevanlinna, H. (Heli), Khan, S. (Sofia), Greco, D. (Dario), Michailidou, K. (Kyriaki), Milne, R.L. (Roger), Muranen, T.A. (Taru), Heikkinen, T. (Tuomas), Aaltonen, K. (Kirsimari), Dennis, J. (Joe), Bolla, M.K. (Manjeet), Liu, J. (Jianjun), Hall, P. (Per), Irwanto, A. (Astrid), Humphreys, M.K. (Manjeet), Li, J. (Jingmei), Czene, K. (Kamila), Chang-Claude, J. (Jenny), Hein, R. (Rebecca), Rudolph, A. (Anja), Seibold, P. (Petra), Flesch-Janys, D. (Dieter), Fletcher, O. (Olivia), Peto, J. (Julian), Santos Silva, I. (Isabel) dos, Johnson, N. (Nichola), Gibson, L.J. (Lorna), Aitken, Z. (Zoe), Hopper, J.L. (John), Tsimiklis, H. (Helen), Bui, M. (Minh), Makalic, E. (Enes), Schmidt, D.F. (Daniel), Southey, M.C. (Melissa), Apicella, C. (Carmel), Stone, J. (Jennifer), Waisfisz, Q. (Quinten), Meijers-Heijboer, E.J. (Hanne), Adank, M.A. (Muriel), Luijt, R.B. (Rob) van der, Meindl, A. (Alfons), Schmutzler, R.K. (Rita), Müller-Myhsok, B. (B.), Lichtner, P. (Peter), Turnbull, C. (Clare), Rahman, N. (Nazneen), Chanock, S.J. (Stephen), Hunter, D. (David), Cox, A. (Angela), Cross, S.S. (Simon), Reed, M.W.R. (Malcolm), Schmidt, M.K. (Marjanka), Broeks, A. (Annegien), Veer, L.J. (Laura) van 't, Hogervorst, F.B.L. (Frans), Fasching, P.A. (Peter), Schrauder, A. (André), Ekici, A.B. (Arif), Beckmann, M.W. (Matthias), Bojesen, S.E. (Stig), Nordestgaard, B.G. (Børge), Nielsen, S.F. (Sune), Flyger, H. (Henrik), Benítez, J. (Javier), Zamora, P.M. (Pilar M.), Perez, J.I.A. (Jose Ignacio Arias), Haiman, C.A. (Christopher), Henderson, B.E. (Brian), Schumacher, F.R. (Fredrick), March, L.L. (Loic Le), Pharoah, P.D.P. (Paul), Dunning, A.M. (Alison), Shah, M. (Mitul), Luben, R.N. (Robert), Brown, J. (Judith), Couch, F.J. (Fergus), Wang, X. (X.), Vachon, C. (Celine), Olson, J.E. (Janet), Lambrechts, D. (Diether), Moisse, M. (Matthieu), Paridaens, R. (Robert), Christiaens, M.R. (Marie Rose), Guénel, P. (Pascal), Truong, T. (Thérèse), Laurent-Puig, P. (Pierre), Mulot, C. (Claire), Marme, F. (Frederick), Burwinkel, B. (Barbara), Schneeweiss, A. (Andreas), Sohn, C. (Christof), Sawyer, E.J. (Elinor), Tomlinson, I.P. (Ian), Kerin, M. (Michael), Miller, N. (Nicola), Andrulis, I.L. (Irene), Knight, J.A. (Julia), Tchatchou, S. (Srine), Mulligan, A.-M. (Anna-Marie), Dörk, T. (Thilo), Bogdanova, N.V. (Natalia), Antonenkova, N.N. (Natalia), Anton-Culver, H. (Hoda), Darabi, H. (Hatef), Eriksson, M. (Mats), García-Closas, M. (Montserrat), Figueroa, J.D. (Jonine), Lissowska, J. (Jolanta), Brinton, L.A. (Louise), Devilee, P. (Peter), Tollenaar, R.A.E.M. (Rob), Seynaeve, C.M. (Caroline), Asperen, C.J. (Christi) van, Kristensen, V. (Vessela), Slager, S. (Susan), Tol, A.E. (Ama E.), Ambrosone, C.B. (Christine), Yannoukakos, D. (Drakoulis), Lindblom, A. (Annika), Margolin, S. (Sara), Radice, P. (Paolo), Peterlongo, P. (Paolo), Barile, M. (Monica), Mariani, P. (Paolo), Hooning, M.J. (Maartje), Martens, J.W.M. (John), Collée, J.M. (Margriet), Jager, A. (Agnes), Jakubowska, A. (Anna), Lubinski, J. (Jan), Jaworska-Bieniek, K. (Katarzyna), Durda, K. (Katarzyna), Giles, G.G. (Graham), McLean, C.A. (Catriona Ann), Brauch, H. (Hiltrud), Brüning, T. (Thomas), Ko, Y.-D. (Yon-Dschun), Brenner, H. (Hermann), Dieffenbach, A.K. (Aida Karina), Arndt, V. (Volker), Stegmaier, C. (Christa), Swerdlow, A.J. (Anthony ), Ashworth, A. (Alan), Orr, N. (Nick), Jones, M. (Michael), Simard, J. (Jacques), Goldberg, M.S. (Mark), Labrèche, F. (France), Dumont, M. (Martine), Winqvist, R. (Robert), Pykäs, K. (Katri), Jukkola-Vuorinen, A. (Arja), Grip, M. (Mervi), Kataja, V. (Vesa), Kosma, V-M. (Veli-Matti), Hartikainen, J.M. (J.), Mannermaa, A. (Arto), Hamann, U. (Ute), Chenevix-Trench, G. (Georgia), Blomqvist, C. (Carl), Aittomäki, K. (Kristiina), Easton, D.F. (Douglas), and Nevanlinna, H. (Heli)

Abstract

Genetic variations, such as single nucleotide polymorphisms (SNPs) in microRNAs (miRNA) or in the miRNA binding sites may affect the miRNA dependent gene expression regulation, which has been implicated in various cancers, including breast cancer, and may alter individual susceptibility to cancer. We investigated associations between miRNA related SNPs and breast cancer risk. First we evaluated 2,196 SNPs in a case-control study combining n

Published
2014
Full Text
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187. MicroRNA Related Polymorphisms and Breast Cancer Risk

Author

Zhao, Z, Khan, S, Greco, D, Michailidou, K, Milne, RL, Muranen, TA, Heikkinen, T, Aaltonen, K, Dennis, J, Bolla, MK, Liu, J, Hall, P, Irwanto, A, Humphreys, K, Li, J, Czene, K, Chang-Claude, J, Hein, R, Rudolph, A, Seibold, P, Flesch-Janys, D, Fletcher, O, Peto, J, Silva, IDS, Johnson, N, Gibson, L, Aitken, Z, Hopper, JL, Tsimiklis, H, Bui, M, Makalic, E, Schmidt, DF, Southey, MC, Apicella, C, Stone, J, Waisfisz, Q, Meijers-Heijboer, H, Adank, MA, van der Luijt, RB, Meindl, A, Schmutzler, RK, Muller-Myhsok, B, Lichtner, P, Turnbull, C, Rahman, N, Chanock, SJ, Hunter, DJ, Cox, A, Cross, SS, Reed, MWR, Schmidt, MK, Broeks, A, Van't Veer, LJ, Hogervorst, FB, Fasching, PA, Schrauder, MG, Ekici, AB, Beckmann, MW, Bojesen, SE, Nordestgaard, BG, Nielsen, SF, Flyger, H, Benitez, J, Zamora, PM, Perez, JIA, Haiman, CA, Henderson, BE, Schumacher, F, Le Marchand, L, Pharoah, PDP, Dunning, AM, Shah, M, Luben, R, Brown, J, Couch, FJ, Wang, X, Vachon, C, Olson, JE, Lambrechts, D, Moisse, M, Paridaens, R, Christiaens, M-R, Guenel, P, Truong, T, Laurent-Puig, P, Mulot, C, Marme, F, Burwinkel, B, Schneeweiss, A, Sohn, C, Sawyer, EJ, Tomlinson, I, Kerin, MJ, Miller, N, Andrulis, IL, Knight, JA, Tchatchou, S, Mulligan, AM, Dork, T, Bogdanova, NV, Antonenkova, NN, Anton-Culver, H, Darabi, H, Eriksson, M, Garcia-Closas, M, Figueroa, J, Lissowska, J, Brinton, L, Devilee, P, Tollenaar, RAEM, Seynaeve, C, van Asperen, CJ, Kristensen, VN, Slager, S, Toland, AE, Ambrosone, CB, Yannoukakos, D, Lindblom, A, Margolin, S, Radice, P, Peterlongo, P, Barile, M, Mariani, P, Hooning, MJ, Martens, JWM, Collee, JM, Jager, A, Jakubowska, A, Lubinski, J, Jaworska-Bieniek, K, Durda, K, Giles, GG, McLean, C, Brauch, H, Bruning, T, Ko, Y-D, Brenner, H, Dieffenbach, AK, Arndt, V, Stegmaier, C, Swerdlow, A, Ashworth, A, Orr, N, Jones, M, Simard, J, Goldberg, MS, Labreche, F, Dumont, M, Winqvist, R, Pylkas, K, Jukkola-Vuorinen, A, Grip, M, Kataja, V, Kosma, V-M, Hartikainen, JM, Mannermaa, A, Hamann, U, Chenevix-Trench, G, Blomqvist, C, Aittomaki, K, Easton, DF, Nevanlinna, H, Zhao, Z, Khan, S, Greco, D, Michailidou, K, Milne, RL, Muranen, TA, Heikkinen, T, Aaltonen, K, Dennis, J, Bolla, MK, Liu, J, Hall, P, Irwanto, A, Humphreys, K, Li, J, Czene, K, Chang-Claude, J, Hein, R, Rudolph, A, Seibold, P, Flesch-Janys, D, Fletcher, O, Peto, J, Silva, IDS, Johnson, N, Gibson, L, Aitken, Z, Hopper, JL, Tsimiklis, H, Bui, M, Makalic, E, Schmidt, DF, Southey, MC, Apicella, C, Stone, J, Waisfisz, Q, Meijers-Heijboer, H, Adank, MA, van der Luijt, RB, Meindl, A, Schmutzler, RK, Muller-Myhsok, B, Lichtner, P, Turnbull, C, Rahman, N, Chanock, SJ, Hunter, DJ, Cox, A, Cross, SS, Reed, MWR, Schmidt, MK, Broeks, A, Van't Veer, LJ, Hogervorst, FB, Fasching, PA, Schrauder, MG, Ekici, AB, Beckmann, MW, Bojesen, SE, Nordestgaard, BG, Nielsen, SF, Flyger, H, Benitez, J, Zamora, PM, Perez, JIA, Haiman, CA, Henderson, BE, Schumacher, F, Le Marchand, L, Pharoah, PDP, Dunning, AM, Shah, M, Luben, R, Brown, J, Couch, FJ, Wang, X, Vachon, C, Olson, JE, Lambrechts, D, Moisse, M, Paridaens, R, Christiaens, M-R, Guenel, P, Truong, T, Laurent-Puig, P, Mulot, C, Marme, F, Burwinkel, B, Schneeweiss, A, Sohn, C, Sawyer, EJ, Tomlinson, I, Kerin, MJ, Miller, N, Andrulis, IL, Knight, JA, Tchatchou, S, Mulligan, AM, Dork, T, Bogdanova, NV, Antonenkova, NN, Anton-Culver, H, Darabi, H, Eriksson, M, Garcia-Closas, M, Figueroa, J, Lissowska, J, Brinton, L, Devilee, P, Tollenaar, RAEM, Seynaeve, C, van Asperen, CJ, Kristensen, VN, Slager, S, Toland, AE, Ambrosone, CB, Yannoukakos, D, Lindblom, A, Margolin, S, Radice, P, Peterlongo, P, Barile, M, Mariani, P, Hooning, MJ, Martens, JWM, Collee, JM, Jager, A, Jakubowska, A, Lubinski, J, Jaworska-Bieniek, K, Durda, K, Giles, GG, McLean, C, Brauch, H, Bruning, T, Ko, Y-D, Brenner, H, Dieffenbach, AK, Arndt, V, Stegmaier, C, Swerdlow, A, Ashworth, A, Orr, N, Jones, M, Simard, J, Goldberg, MS, Labreche, F, Dumont, M, Winqvist, R, Pylkas, K, Jukkola-Vuorinen, A, Grip, M, Kataja, V, Kosma, V-M, Hartikainen, JM, Mannermaa, A, Hamann, U, Chenevix-Trench, G, Blomqvist, C, Aittomaki, K, Easton, DF, and Nevanlinna, H

Abstract

Genetic variations, such as single nucleotide polymorphisms (SNPs) in microRNAs (miRNA) or in the miRNA binding sites may affect the miRNA dependent gene expression regulation, which has been implicated in various cancers, including breast cancer, and may alter individual susceptibility to cancer. We investigated associations between miRNA related SNPs and breast cancer risk. First we evaluated 2,196 SNPs in a case-control study combining nine genome wide association studies (GWAS). Second, we further investigated 42 SNPs with suggestive evidence for association using 41,785 cases and 41,880 controls from 41 studies included in the Breast Cancer Association Consortium (BCAC). Combining the GWAS and BCAC data within a meta-analysis, we estimated main effects on breast cancer risk as well as risks for estrogen receptor (ER) and age defined subgroups. Five miRNA binding site SNPs associated significantly with breast cancer risk: rs1045494 (odds ratio (OR) 0.92; 95% confidence interval (CI): 0.88-0.96), rs1052532 (OR 0.97; 95% CI: 0.95-0.99), rs10719 (OR 0.97; 95% CI: 0.94-0.99), rs4687554 (OR 0.97; 95% CI: 0.95-0.99, and rs3134615 (OR 1.03; 95% CI: 1.01-1.05) located in the 3' UTR of CASP8, HDDC3, DROSHA, MUSTN1, and MYCL1, respectively. DROSHA belongs to miRNA machinery genes and has a central role in initial miRNA processing. The remaining genes are involved in different molecular functions, including apoptosis and gene expression regulation. Further studies are warranted to elucidate whether the miRNA binding site SNPs are the causative variants for the observed risk effects.

Published
2014

188. MicroRNA Related Polymorphisms and Breast Cancer Risk

Author

Khan, Salima, Greco, D, Michailidou, K, Milne, RL, Muranen, TA, Heikkinen, T, Aaltonen, K, Dennis, J, Bolla, MK, Liu, J (Jingjing), Hall, P, Irwanto, A, Humphreys, K, Li, J, Czene, K, Chang-Claude, J, Hein, R, Rudolph, A, Seibold, P, Flesch-Janys, D, Fletcher, O, Peto, J, Silva, ID, Johnson, N, Gibson, L, Aitken, Z, Hopper, JL, Tsimiklis, H, Bui, M, Makalic, E, Schmidt, DF, Southey, MC, Apicella, C, Stone, J, Waisfisz, Q, Meijers-Heijboer, H, Adank, MA (Muriel), van der Luijt, RB, Meindl, A, Schmutzler, RK, Muller-Myhsok, B, Lichtner, P, Turnbull, C, Rahman, N, Chanock, SJ, Hunter, DJ, Cox, A, Cross, SS, Reed, MWR, Schmidt, MK (Marjanka), Broeks, A, van 't Veer, LJ (Laura), Hogervorst, FB, Fasching, PA, Schrauder, MG, Ekici, AB, Beckmann, MW, Bojesen, SE, Nordestgaard, BG, Nielsen, SF, Flyger, H, Benitez, J, Zamora, PM, Perez, JIA, Haiman, CA, Henderson, BE, Schumacher, F, Le Marchand, L, Pharoah, PDP, Dunning, AM, Shah, M, Luben, R, Brown, J, Couch, FJ, Wang, X, Vachon, C, Olson, JE, Lambrechts, D, Moisse, M, Paridaens, R, Christiaens, MR, Guenel, P, Truong, T, Laurent-Puig, P, Mulot, C, Marme, F, Burwinkel, B, Schneeweiss, A, Sohn, C, Sawyer, EJ, Tomlinson, I, Kerin, MJ, Miller, N, Andrulis, IL, Knight, JA, Tchatchou, S, Mulligan, AM, Dork, T, Bogdanova, NV, Antonenkova, NN, Anton-Culver, H, Darabi, H, Eriksson, M, Garcia-Closas, M, Figueroa, J, Lissowska, J, Brinton, L, Devilee, P, Tollenaar, RAEM, Seynaeve, Caroline, van Asperen, CJ, Kristensen, VN, Slager, S, Toland, AE, Ambrosone, CB, Yannoukakos, D, Lindblom, A, Margolin, S, Radice, P, Peterlongo, P, Barile, M, Mariani, P, Hooning, Maartje, Martens, John, Collee, Margriet, Jager, Agnes, Jakubowska, A, Lubinski, J, Jaworska-Bieniek, K, Durda, K, Giles, GG, McLean, C, Brauch, H, Bruning, T, Ko, YD, Brenner, H, Dieffenbach, AK, Arndt, V, Stegmaier, C, Swerdlow, A, Ashworth, A, Orr, N, Jones, M, Simard, J, Goldberg, MS, Labreche, F, Dumont, M, Winqvist, R, Pylkas, K, Jukkola-Vuorinen, A, Grip, M, Kataja, V, Kosma, VM, Hartikainen, JM, Mannermaa, A, Hamann, U, Chenevix-Trench, G, Blomqvist, C, Aittomaki, K, Easton, DF, Nevanlinna, H, Khan, Salima, Greco, D, Michailidou, K, Milne, RL, Muranen, TA, Heikkinen, T, Aaltonen, K, Dennis, J, Bolla, MK, Liu, J (Jingjing), Hall, P, Irwanto, A, Humphreys, K, Li, J, Czene, K, Chang-Claude, J, Hein, R, Rudolph, A, Seibold, P, Flesch-Janys, D, Fletcher, O, Peto, J, Silva, ID, Johnson, N, Gibson, L, Aitken, Z, Hopper, JL, Tsimiklis, H, Bui, M, Makalic, E, Schmidt, DF, Southey, MC, Apicella, C, Stone, J, Waisfisz, Q, Meijers-Heijboer, H, Adank, MA (Muriel), van der Luijt, RB, Meindl, A, Schmutzler, RK, Muller-Myhsok, B, Lichtner, P, Turnbull, C, Rahman, N, Chanock, SJ, Hunter, DJ, Cox, A, Cross, SS, Reed, MWR, Schmidt, MK (Marjanka), Broeks, A, van 't Veer, LJ (Laura), Hogervorst, FB, Fasching, PA, Schrauder, MG, Ekici, AB, Beckmann, MW, Bojesen, SE, Nordestgaard, BG, Nielsen, SF, Flyger, H, Benitez, J, Zamora, PM, Perez, JIA, Haiman, CA, Henderson, BE, Schumacher, F, Le Marchand, L, Pharoah, PDP, Dunning, AM, Shah, M, Luben, R, Brown, J, Couch, FJ, Wang, X, Vachon, C, Olson, JE, Lambrechts, D, Moisse, M, Paridaens, R, Christiaens, MR, Guenel, P, Truong, T, Laurent-Puig, P, Mulot, C, Marme, F, Burwinkel, B, Schneeweiss, A, Sohn, C, Sawyer, EJ, Tomlinson, I, Kerin, MJ, Miller, N, Andrulis, IL, Knight, JA, Tchatchou, S, Mulligan, AM, Dork, T, Bogdanova, NV, Antonenkova, NN, Anton-Culver, H, Darabi, H, Eriksson, M, Garcia-Closas, M, Figueroa, J, Lissowska, J, Brinton, L, Devilee, P, Tollenaar, RAEM, Seynaeve, Caroline, van Asperen, CJ, Kristensen, VN, Slager, S, Toland, AE, Ambrosone, CB, Yannoukakos, D, Lindblom, A, Margolin, S, Radice, P, Peterlongo, P, Barile, M, Mariani, P, Hooning, Maartje, Martens, John, Collee, Margriet, Jager, Agnes, Jakubowska, A, Lubinski, J, Jaworska-Bieniek, K, Durda, K, Giles, GG, McLean, C, Brauch, H, Bruning, T, Ko, YD, Brenner, H, Dieffenbach, AK, Arndt, V, Stegmaier, C, Swerdlow, A, Ashworth, A, Orr, N, Jones, M, Simard, J, Goldberg, MS, Labreche, F, Dumont, M, Winqvist, R, Pylkas, K, Jukkola-Vuorinen, A, Grip, M, Kataja, V, Kosma, VM, Hartikainen, JM, Mannermaa, A, Hamann, U, Chenevix-Trench, G, Blomqvist, C, Aittomaki, K, Easton, DF, and Nevanlinna, H

Abstract

Genetic variations, such as single nucleotide polymorphisms (SNPs) in microRNAs (miRNA) or in the miRNA binding sites may affect the miRNA dependent gene expression regulation, which has been implicated in various cancers, including breast cancer, and may alter individual susceptibility to cancer. We investigated associations between miRNA related SNPs and breast cancer risk. First we evaluated 2,196 SNPs in a case-control study combining nine genome wide association studies (GWAS). Second, we further investigated 42 SNPs with suggestive evidence for association using 41,785 cases and 41,880 controls from 41 studies included in the Breast Cancer Association Consortium (BCAC). Combining the GWAS and BCAC data within a meta-analysis, we estimated main effects on breast cancer risk as well as risks for estrogen receptor (ER) and age defined subgroups. Five miRNA binding site SNPs associated significantly with breast cancer risk: rs1045494 (odds ratio (OR) 0.92; 95% confidence interval (CI): 0.88-0.96), rs1052532 (OR 0.97; 95% CI: 0.95-0.99), rs10719 (OR 0.97; 95% CI: 0.94-0.99), rs4687554 (OR 0.97; 95% CI: 0.95-0.99, and rs3134615 (OR 1.03; 95% CI: 1.01-1.05) located in the 3' UTR of CASP8, HDDC3, DROSHA, MUSTN1, and MYCL1, respectively. DROSHA belongs to miRNA machinery genes and has a central role in initial miRNA processing. The remaining genes are involved in different molecular functions, including apoptosis and gene expression regulation. Further studies are warranted to elucidate whether the miRNA binding site SNPs are the causative variants for the observed risk effects.

Published
2014

189. Prétopologie et applications : un état de l'art

Author

J.-P., Auray, Bonnevay, S., Bui, M., Duru, G., Lamure, M., Laboratoire d'informatique et des systèmes complexes (LAISC), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), and Tijus, Charles

Subjects
[SHS.INFO]Humanities and Social Sciences/Library and information sciences, [SHS.INFO] Humanities and Social Sciences/Library and information sciences
Published
2009

190. Сезонные изменения физических свойств агара и биомассы Gracilaria tenuistipitata из залива Ньячанг, Центральный Вьетнам

Author

Bui, M., TRAN THI T.V., Le, N., Nguyen, Q., and Podkorytova, A.

Subjects
АГАР, ФИЗИКО-ХИМИЧЕСКИЕ СВОЙСТВА, БИОМАССА, СЕЗОННОСТЬ, ПАРАМЕТРЫ ОКРУЖАЮЩЕЙ СРЕДЫ
Abstract

Seasonal variation of Gracilaria tenuistipitata biomass and physical properties of agar from this red alga growing in the Song Cai River estuary (Nhatrang Bay) was monitored from January to December 2005. The biomass increased from January to March (in spring) to the maximum wet weight 475 g/m2 and then declined gradually. The yield and gel strength of agar had a prominent variation, the range of agar yield fluctuation in the period from April to August was 11-28 % of dry weight. Alkaline treatment lowered the agar yield to 9.3-23.8 %, while sulfate concentration had 70.0-72.4 % decreasing, the content of 3,6-anhydrogalactose had 22.0-59.9 % increasing, and the content of 6-O-methyl galactose did not change. Gel strength increased to the maximum value 923 g/cm2 (for 1 % agar solution) after the 2-hour alkaline treatment by 6 % NaOH at 70-80 oC (for the specimens collected in March before the peak of biomass and agar yield). Thus, the algae G. tenuistipitata from the coastal zone of Nhatrang Bay has the content and quality of agar sufficient to be considered as raw material for food-grade agar production.

Published
2009

191. A pretopological Self-organizing Algorithm

Author

Gros-Désormeaux, H., Amor S., Ben, Bui, M., Tijus, Charles, Cognitions Humaine et ARTificielle (CHART), Université Paris 8 Vincennes-Saint-Denis (UP8)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Nanterre (UPN)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Laboratoire d'informatique et des systèmes complexes (LAISC), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), and École pratique des hautes études (EPHE)-Université Paris 8 Vincennes-Saint-Denis (UP8)-Université Paris Nanterre (UPN)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)

Subjects
ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2008

192. A stochastic and pretopological modeling aerial pollution of an urban area

Author

Benamor, S., Bonnevay, S., Bui, M., Lamure, M., Cognitions Humaine et ARTificielle (CHART), Université Paris 8 Vincennes-Saint-Denis (UP8)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Nanterre (UPN)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Laboratoire d'informatique et des systèmes complexes (LAISC), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), Laboratoire d'InfoRmatique en Image et Systèmes d'information (LIRIS), Université Lumière - Lyon 2 (UL2)-École Centrale de Lyon (ECL), Université de Lyon-Université de Lyon-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA), École pratique des hautes études (EPHE)-Université Paris 8 Vincennes-Saint-Denis (UP8)-Université Paris Nanterre (UPN)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Parallélisme, Réseaux, Systèmes, Modélisation (PRISM), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Centre National de la Recherche Scientifique (CNRS), Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-École Centrale de Lyon (ECL), Université de Lyon-Université Lumière - Lyon 2 (UL2), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Université Paris Nanterre (UPN)-Université Paris 8 Vincennes-Saint-Denis (UP8)-École pratique des hautes études (EPHE), Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS), Tijus, Charles, Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Centre National de la Recherche Scientifique (CNRS)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), and Shtalbi, Haki

Subjects
[SHS.INFO]Humanities and Social Sciences/Library and information sciences, [SHS] Humanities and Social Sciences, [SHS.INFO] Humanities and Social Sciences/Library and information sciences, ComputingMilieux_MISCELLANEOUS, [SHS]Humanities and Social Sciences
Abstract

International audience

Published
2008

193. Passivation of Laser-Drilled Via Holes for Emitter-Wrap-Through-Cells

Author

Mingirulli, N., Trittler, S., Bui, M., Grohe, A., Biro, D., Preu, R., and Glunz, S.W.

Subjects
Mono- and Multicrystalline Silicon Cells and Materials, Processing Technology of, Wafer-Based Silicon Solar Cells and Materials Technology
Abstract

23rd European Photovoltaic Solar Energy Conference and Exhibition, 1-5 September 2008, Valencia, Spain; 996-999, A high speed via-hole drilling laser process for emitter-wrap through cell production is investigated concerning the removal of induced crystal damage by a subsequent alkaline etching step. The etching time necessary for damage removal is identified. Further the passivating properties at the via-hole surface of two passivation layers are compared. The passivating effect of a PECVD-SiN layer deposited on both sides of the wafers is confronted to thermal oxide passivation by lifetime measurement. A theoretical frame work using the analogy of via-holes and dislocations is applied to extract values for the surface recombination velocity at the via-hole wall. Both analysis indicate that the passivating effect of the PECVD layer depends on the via hole radius whereas the passivation quality of the SiO2-layer saturates for an etching time of equal or greater 240 s. For the highest etching times surface recombination velocities of down to 60 cm/s are found for SiN.

Published
2008
Full Text
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194. Open Multi-Technology Service Oriented Architectur for 'Its' Business Models: The ITSIBus Etoll Services

Author

Gastão C. Jacquet, J. Sales Gomes, Paulo Araújo, A. Luís Osório, Carlos Gorçalves, M. Barata, and Bui M. Dias

Subjects
Flexibility (engineering), Process management, business.industry, Computer science, Business process, Information and Communications Technology, Service-oriented infrastructure, Business model, business, Implementation, Payment card, Agile software development
Abstract

The development of integrated solutions made of systems based on different technologies, adopting different implementation approaches and different versions is a complex challenge. The lack of standards or differences in implementations when they exist, are important obstacles to the construction of integrated, flexible and agile solutions. The incorporation of systems from different vendors and systems that evolve to answer innovation processes, suggests the advantage for a multi-technology systems strategy. This paper discusses the ITSIBus approach based on, a multi-technology service oriented infrastructure where specialized pluggable systems run services following a peer to peer architecture. The multi-technology approach is based on the discussed System Broker concept. The agility required by a crescent number of collaborative business process requires an advanced flexibility from the ICT technological infrastructure. The ITSIBus approach is also discussed as a grounding platform to support enterprise collaborative networks considering that services in different companies are based on different technologies.

Published
2006

195. What are the differences among occupational groups related to their palliative care-specific educational needs and intensity of interprofessional collaboration in long-term care homes?

Author

Kaasalainen, S., Sussman, T., Bui, M., Akhtar-Danesh, N., Laporte, R. D., McCleary, L., Wickson Griffiths, A., Brazil, K., Parker, D., Dal Bello-Haas, V., Papaioannou, A., and O'Leary, J.

Subjects
MEDICAL education, AGING, ANALYSIS of variance, EDUCATION, INDUSTRIAL hygiene, INTERDISCIPLINARY education, LONG-term health care, NURSING care facilities, PALLIATIVE treatment, QUESTIONNAIRES, RESEARCH funding, SURVEYS, TERMINALLY ill, WORK, DATA analysis software, UNLICENSED medical personnel
Abstract

Background: The purpose of this study was to compare the differences across occupational groups related to their end-of-life care-specific educational needs and reported intensity of interprofessional collaboration in long-term care (LTC) homes. Methods: A cross-sectional survey, based on two questionnaires, was administered at four LTC homes in Ontario, Canada using a modified Dilman's approach. The first questionnaire, End of Life Professional Caregiver Survey, included three domains: patients and family-centered communication, cultural and ethical values, effective care delivery. The Intensity of Interprofessional Collaboration Scale included two subscales: care sharing activities, and interprofessional coordination. In total, 697 LTC staff were given surveys, including personal support workers, support staff (housekeeping, kitchen, recreation, laundry, dietician aids, office staff), and registered staff (licensed nurses, physiotherapists, social workers, pharmacists, physicians). Results: A total of 317 participants completed the survey (126 personal support workers, 109 support staff, 82 registered staff) for a response rate of 45%. Significant differences emerged among occupational groups across all scales and subscales. Specifically, support staff rated their comfort of working with dying patients significantly lower than both nurses and PSWs. Support staff also reported significantly lower ratings of care sharing activities and interprofessional coordination compared to both registered staff and personal support workers. Conclusions: These study findings suggest there are differing educational needs and sense of interprofessional collaboration among LTC staff, specific to discipline group. Both the personal support workers and support staff groups appeared to have higher needs for education; support staff also reported higher needs related to integration on the interdisciplinary team. Efforts to build capacity within support staff related to working with dying residents and their families are needed. Optimal palliative care may require resources to increase the availability of support for all staff involved in the care of patients. [ABSTRACT FROM AUTHOR]

Published
2017
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196. Micronutrient status and intake in omnivores, vegetarians and vegans in Switzerland.

Author

Wegmüller, R., Schüpbach, R., Herter-Aeberli, I., Berguerand, C., and Bui, M.

Subjects
DIETARY supplements, NUTRITIONAL assessment, QUESTIONNAIRES, VEGETARIANISM, LIFESTYLES, FOOD diaries, PHYSICAL activity, DESCRIPTIVE statistics, NUTRITIONAL status
Abstract

Purpose: Vegetarian and vegan diets have gained popularity in Switzerland. The nutritional status of individuals who have adopted such diets, however, has not been investigated. The aim of this study was to assess the intake and status of selected vitamins and minerals among vegetarian and vegan adults living in Switzerland. Methods: Healthy adults [omnivores (OVs), n = 100; vegetarians (VGs), n = 53; vegans (VNs), n = 53] aged 18-50 years were recruited, and their weight and height were measured. Plasma concentrations of the vitamins A, C, E, B1, B2, B6, B12, folic acid, pantothenic acid, niacin, biotin and β-carotene and of the minerals Fe, Mg and Zn and urinary iodine concentration were determined. Dietary intake was assessed using a three-day weighed food record, and questionnaires were issued in order to assess the physical activity and lifestyle of the subjects. Results: Omnivores had the lowest intake of Mg, vitamin C, vitamin E, niacin and folic acid. Vegans reported low intakes of Ca and a marginal consumption of the vitamins D and B12. The highest prevalence for vitamin and mineral deficiencies in each group was as follows: in the omnivorous group, for folic acid (58 %); in the vegetarian group, for vitamin B6 and niacin (58 and 34 %, respectively); and in the vegan group, for Zn (47 %). Despite negligible dietary vitamin B12 intake in the vegan group, deficiency of this particular vitamin was low in all groups thanks to widespread use of supplements. Prevalence of Fe deficiency was comparable across all diet groups. Conclusions: Despite substantial differences in intake and deficiency between groups, our results indicate that by consuming a well-balanced diet including supplements or fortified products, all three types of diet can potentially fulfill requirements for vitamin and mineral consumption. [ABSTRACT FROM AUTHOR]

Published
2017
Full Text
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