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153. EDUKLAB Educational Innovation Laboratory: An experience that promotes teaching creativity

Author

Betancurth Becerra, Carlos Mario, Suarez Albano, Diana Carolina, Diosa Vásquez, Natalia, Betancurth Becerra, Carlos Mario, Suarez Albano, Diana Carolina, and Diosa Vásquez, Natalia

Abstract

The text presents the teaching experience of the EDUKLAB Educational Innovation Laboratory in the city of Ibagué, Tolima, Colombia in 2019, at the Mariano Melendro Educational Institution. This proposal is linked to national projects for the inclusion of technologies in classrooms such as Computers to Educate and is installed in the context of educational policies and technological appropriation plans of the ministries of technology, communication, culture and education from a critical stance in its updating processes, since it presents an encouraging panorama and an opportunity for educational innovation thought from the context. At the same time, it is invited to recognize the importance of technology in schools based on the reflections aroused by the field of communication-education, accounting for the transformations of a current situation mitigated by new ways of being a teacher and student, the social and cultural configurations, the tensions between uses, rituals and knowledge that are in permanent tension with the daily use of digital technologies., En el siguiente proceso investigativo se presenta una experiencia docente desde el laboratorio de Innovación Educativa EDUKLAB en la ciudad de Ibagué Tolima (Colombia) durante el año 2019 en la Institución Educativa Mariano Melendro. Esta propuesta se encuentra vinculada a los proyectos nacionales de inclusión tecnológica en las aulas de clase como Computadores para Educar y se instala en el contexto de las políticas educativas y los planes de apropiación tecnológica de los ministerios de tecnologías, comunicación, cultura y educación desde una postura crítica en sus procesos de actualización, ya que presenta un panorama alentador y una oportunidad de innovación educativa pensada desde el contexto. Al mismo tiempo se invita a reconocer la importancia de la tecnología en las escuelas a partir de las reflexiones que suscita el campo la comunicación-educación, exponiendo las transformaciones de un escenario de actualidad mitigado por nuevas formas de ejercer el rol docente y estudiante, las configuraciones sociales y culturales, las tensiones entre usos, ritualidades y saberes que están en tensión permanente con el uso cotidiano de las tecnologías digitales.

Published
2020

154. Análisis de la generación de rentas propias por el municipio de Ocaña en el periodo 2009-2017

Author

Sánchez Becerra, Carlos Andrés, Rodríguez, Alex Mauricio, Sánchez Becerra, Carlos Andrés, and Rodríguez, Alex Mauricio

Abstract

This research incorporates theoretical elements of fiscal federalism, structures and levels of government, decentralization, information and needs assesment in local, and types of local income and expenses. Likeswise, it seeks to know how the fiscal decentralization process has been in the municipality of Ocaña from the perspective of the capacity to generate its income based on the revenues that the Constitution and the law have granted and whose regulations are found in the municipal agreement 042 of 2009 "Tax Statute of the Municipality of Ocaña". Also, public accounting information available in the Treasury and Public Information Consolidator (CHIP) and the resolutions of the General Accounting Office of the Nation on the categorization of municipalities. With this information, comparative analyses of the collections and their relative weights over revenues were carried out, understanding the performance of the municipal finance to manage and collect its income in the period 2009-2017. It is remarkable that, although the tax collection has had significant growth, its performance is lower than other municipalities with similar population characteristics., La presente investigación incorpora elementos teóricos del federalismo fiscal, estructuras y niveles de gobierno, descentralización, información y determinación de necesidades en lo local, y tipos de ingresos y gastos locales. Así mismo, busca conocer cómo ha sido el proceso de descentralización fiscal en el municipio de Ocaña desde la perspectiva de la capacidad para generar sus propios ingresos con base en las rentas que la constitución y la ley le han otorgado y cuya reglamentación se encuentra en el acuerdo municipal 042 de 2009 "Estatuto Tributario del Municipio de Ocaña". También, se dispone de la información contable pública disponible en el consolidador de Hacienda e Información Pública (CHIP) y las resoluciones de la Contaduría General de la Nación sobre categorización de municipios. Con esta información se realizaron análisis comparativos de los recaudos y sus pesos relativos sobre los ingresos, comprendiendo el desempeño de la fiscal hacienda municipal para gestionar y recaudar sus rentas propias en el periodo 2009-2017. Se resalta que, aunque el recaudo fiscal ha tenido un crecimiento significativo, su desempeño es inferior a otros municipios de similares características poblacionales.

Published
2020

159. Interleukin-6 as a Biomarker of Early-Onset Neonatal Sepsis.

Author

Cortés, José S., Losada, Paula X., Fernández, Laura X., Beltrán, Emilce, DeLaura, Isabel, Narváez, Carlos F., and Fonseca-Becerra, Carlos Eduardo

Subjects
INTERLEUKINS, BIOMARKERS, C-reactive protein, STATISTICS, NEONATAL sepsis, SCIENTIFIC observation, CASE-control method, AGE factors in disease, ENZYME-linked immunosorbent assay, DESCRIPTIVE statistics, STATISTICAL sampling, RECEIVER operating characteristic curves, DATA analysis, ODDS ratio
Abstract

Objective  The aim of this study is to determine the utility of C reactive protein (CRP) and interleukin (IL)-6 in the diagnosis of neonatal sepsis (NS) in a neonatal intensive care unit (NICU) in the south of Colombia. Study Design  A nonmatched case–control study was conducted. Convenience sampling was performed. Data were obtained from clinical records. IL-6 levels were determined using enzyme-linked immunosorbent assay. Receiver operator characteristic (ROC) curve analysis and Youden's index were used to determine the optimal cutoffs for CRP and IL-6 levels in diagnosing NS, early-onset NS (EONS), and late-onset NS (LONS). Results  Data from 31 cases and 62 controls were included. History of chorioamnionitis (infinite odds ratio [OR] [3.07-infinity]), and the presence of meconium-stained amniotic fluid during birth (OR: 9.04 [1.35–112]) were identified as risk factors for NS. Differences in CRP (p  < 0.0001) and IL-6 (p  < 0.0485) levels were also found, more significantly for LONS and EONS patients, respectively. In the diagnosis of LONS using CRP levels, the area under the ROC curve (AUC) was 0.8371 (p  < 0.0001). The optimal cutoff was 0.53 mg/dL. For EONS diagnosis using IL-6, the AUC was 0.6869 (p  = 0.0315) and the optimal cutoff was 17.75 pg/mL. Conclusion  Differences between CRP and IL-6 levels were found between control and NS groups. Furthermore, CRP showed greater potential diagnostic utility in the LONS group, whereas IL-6 showed greater potential utility in the EONS group. Key Points NS is a major morbimortality cause worldwide CRP and IL-6 levels may be useful NS biomarkers No biomarker alone is enough for the diagnosis of NS [ABSTRACT FROM AUTHOR]

Published
2021
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161. Edulab: diseño de una estrategia educativa basada en las prácticas de la cultura digital

Author

Betacurth Becerra, Carlos Mario and Gómez Palacio, Jhon Estiwar

Subjects
Comunicaciones digitales, Tecnología educativa, Cibercultura, Tecnología de la información - Aspectos educativos
Abstract

Este documento da cuenta de la investigación sobre los Laboratorios Educativos EDULABS que inició en la Universidad Tecnológica de Pereira durante el año 2017. La investigación aborda temas alrededor de la cibercultura como un escenario de transformaciones que implican pensar en el uso e implementación de las tecnologías en los espacios educativos; las tensiones que generan, los antecedentes latinoamericanos sobre tecnologías educativas, la apropiación tecnológica como una condición para ir más allá del uso y la comunicación educativa como un campo de reflexión constituyen el tema de investigación. A partir de la metodología de Pensamiento de Diseño para Educadores de la Universidad de Stanford, se propone diseñar una estrategia educativa basada en laboratorios, a partir de tres momentos claves; 1. Observar como una forma en la cual se puede comprender a las personas para co-diseñar una solución a la pregunta de investigación; 2. Diseño, donde se realizan actividades como mapas de afinidades, definición de criterios para el diseño de la estrategia; y 3. Implementación y evaluación, donde se describen las actividades que se proponen dentro de la estrategia y los resultados en cuanto a la implementación.

Published
2019

162. Enalapril Influence on Arterial Stiffness in Rheumatoid Arthritis Women: A Randomized Clinical Trial

Author

Perez-Vazquez, Felipe, primary, Bäck, Magnus, additional, Chavarria-Avila, Efrain, additional, Gomez-Bañuelos, Eduardo, additional, Ramos-Becerra, Carlos G., additional, Pizano-Martínez, Óscar, additional, Salazar-Páramo, Mario, additional, Grover-Páez, Fernando, additional, Nava-Zavala, Arnulfo H., additional, Cardona-Muñoz, Ernesto G., additional, Cardona-Müller, David, additional, Duran-Barragán, Sergio, additional, Mera-Riofrio, Valeria N., additional, Prado-Bachega, Natalia, additional, and Vazquez-Del Mercado, Monica, additional

Published
2020
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169. Diseño Curricular basado en Competencias, para superar la Asistemacidad de la Asignatura Didáctica de la Matemática, en la Especialidad Matemática y Computación de la Fachse-Unprg-Lambayeque-2013

Author

Inoñan Becerra, Carlos Enrique and Rodas Malca, Agustin

Subjects
Aprendizaje Matemático, Didáctica de las Matemáticas, Competencias Matemáticas
Abstract

El problema que se aborda en la investigación, es el desarrollo asistémico y descontextualizado de la asignatura didáctica de la matemática, en el proceso académico profesional correspondiente a la especialidad de Matemática y Computación en la FACHSE-UNPRG. El objetivo capital del estudio fue elaborar un diseño curricular basado en competencias, para efectos de configurar potencialidades que coadyuven a un buen desempeño. La conjetura o hipótesis quedó expresada en términos como “Si se diseña un Diseño Curricular basado en Competencias, entonces se supera la asistematicidad y descontextualización de la asignatura didáctica de la matemática…”. El estudio adquiere transcendencia porque significa un aporte de innovación pedagógica curricular en el campo de la formación profesional. Se trabajó con una metodología pluridimensional, característica de las investigaciones mixtas. El logro fundamental fue la configuración de la propuesta con carácter sistémico, en el cual se distinguen tres niveles macroproceso o direccionamiento, mesoproceso u organización curricular y microporceso o diseños didácticos. Concluyendo que: el Diseño Curricular Basado en Competencias, planteado para la Asignatura Didáctica de la Matemática, es un sistema integrado por tres niveles Macroproceso o Direccionamiento, Mesoproceso u Organización Curricular y Microporceso o Diseños Didácticos. Tesis

Published
2018

170. Confiabilidad de un monitor automatizado para la medición de la presión arterial

Author

Cardona-Müller, David, Grover-Páez, Fernando, Guzmán-Saldivar, Víctor, Alanis-Sánchez, Guillermo A., Murguía-Soto, César, Totsuka-Sutto, Sylvia E., Quezada-Fernández, Patricia, Macías-Chumacera, Agustín, Cardona-Muñoz, Ernesto G., and Ramos-Becerra, Carlos G.

Subjects
Hypertension, Blood Pressure, Blood Pressure Determination
Abstract

Background A correct blood pressure (BP) measurement is essential for the diagnosis and control of high BP. Aim: To evaluate the agreement and repeatability of BP measurements with the OMRON HEM-7320-LA device compared to a mercury sphygmomanometer. Material and Methods: A cross-sectional study comparing BP measurements made by two randomly selected trained nurses and an automatic oscillometric device. The mercurial sphygmomanometer was connected to the automated device via a “T” type connector and a dual-head stethoscope was used, allowing simultaneous measurements. The results were analyzed with one-factor analysis of variance, Bland-Altman's test, repeatability coefficient (RC), and intra-class correlation coefficient (ICC). Results: Forty-nine participants aged 56 ± 19 years were included. Nineteen had hypertension (38%). We did not observe a significant difference in either systolic (SBP) or diastolic blood pressure (DBP) pressure measurements between the observers and the device. The mean difference was −0.09 mmHg (95% confidence intervals (CI)-0.9 to 0.7) for SBP and −0.9 mmHg (95% CI −1.7 to −0.13) for DBP. The RC for SBP (6.2, 5.2 and 5.8 mmHg) and DBP (4.7, 4.2 y 5.2 mmHg) was similar between the observers and the device. The ICC for SBP was 0.990 (95% CI 0.983 to 0.995, p < 0.01) and 0.986 (95% CI 0.977 to 0.991, p < 0.01) for DBP. Conclusions: There was a high level of agreement and similar measurement repeatability in the measurements performed by the automatic device and the mercurial sphygmomanometer. No differences in BP measurements were observed.

Published
2018

172. Abstract C048: Novel master checkpoint Cbl-b siRNA-based adoptive cellular therapy: Superior antitumor efficacy in a syngeneic murine hepatocellular carcinoma Hepa1-6 model following APN401 monotherapy and synergistic effects with anti-PD1

Author

Gaweco, Anderson, primary, Thell, Kathrin, additional, Urban, Maria, additional, Harrauer, Julia, additional, Haslinger, Isabella, additional, Dohnal, Alexander, additional, Lametschwandtner, Guenther, additional, Drobits, Karin, additional, Gugenberger, Romana, additional, Muehleisen, Hannes, additional, Penninger, Josef, additional, Becerra, Carlos, additional, Chung, Vincent, additional, and El-Khoueiry, Anthony, additional

Published
2019
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174. Sub-nucleosomal organization in urine cell-free DNA

Author

Markus, Havell, primary, Zhao, Jun, additional, Contente-Cuomo, Tania, additional, Raupach, Elizabeth, additional, Odenheimer-Bergman, Ahuva, additional, Connor, Sydney, additional, McDonald, Bradon R., additional, Hutchins, Elizabeth, additional, McGilvery, Marissa, additional, de la Maza, Michelina C., additional, Van Keuren-Jensen, Kendall, additional, Pirrotte, Patrick, additional, Goel, Ajay, additional, Becerra, Carlos, additional, Von Hoff, Daniel D., additional, Celinski, Scott A., additional, Hingorani, Pooja, additional, and Murtaza, Muhammed, additional

Published
2019
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175. AB1259 EVALUATION OF ENALAPRIL ON ARTERIAL STIFFNESS IN RHEUMATOID ARTHRITIS IN A RANDOMISED CLINICAL TRIAL

Author

Perez-Vazquez, Felipe, primary, Barragan, Sergio Duran, additional, Gomez-Bañuelos, Eduardo, additional, Avila, Efrain Chavarria, additional, Becerra, Carlos Ramos, additional, Diaz-Rubio, Gustavo-Ignacio, additional, Salazar-Paramo, Mario, additional, Páez, Fernando Grover, additional, Nava-Zavala, Arnulfo Hernán, additional, Cardona-Muñoz, Ernesto G., additional, Müller, David Cardona, additional, Navarro-Hernández, Rosa E., additional, Mera-Riofrio, Valeria-Nicole, additional, Prado-Bachega, Natalia, additional, and Vazquez-Del-Mercado, Monica, additional

Published
2019
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176. FRI0545 HEMODYNAMIC MEASUREMENTS AND ARTERIAL STIFFNESS IN PATIENTS WITH JUVENILE IDIOPATIC ARTHRITIS COMPARED TO CHILDREN WITHOUT JUVENILE IDIOPATIC ARTHRITIS

Author

Rubio Silveira, Jorge E., primary, Araceli Arellano Valdez, C., additional, Becerra, Carlos Ramos, additional, Nuñez, Myriam Mendez, additional, Müller, David Cardona, additional, Flores, Oscar Mares, additional, García, Priscila Vega, additional, Páez, Fernando Grover, additional, and Parra, Alberto Tlacuilo, additional

Published
2019
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177. Ligand-inducible, prostate stem cell antigen (PSCA)-directed GoCAR-T cells in advanced solid tumors: Preliminary results with cyclophosphamide (Cy) ± fludarabine (Flu) lymphodepletion (LD).

Author

Becerra, Carlos Roberto, primary, Manji, Gulam Abbas, additional, Kim, Dae Won, additional, Gardner, Olivia, additional, Malankar, Aditya, additional, Shaw, Joanne, additional, Blass, Devin, additional, Yi, Xiaohui, additional, Foster, Aaron E., additional, and Woodard, Paul, additional

Published
2019
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178. Effect of green tea extract on arterial stiffness, lipid profile and sRAGE in patients with type 2 diabetes mellitus: a randomised, double-blind, placebo-controlled trial

Author

Quezada-Fernández, Patricia, primary, Trujillo-Quiros, Jhonatan, additional, Pascoe-González, Sara, additional, Trujillo-Rangel, Walter A., additional, Cardona-Müller, David, additional, Ramos-Becerra, Carlos G., additional, Barocio-Pantoja, Maricruz, additional, Rodríguez-de la Cerda, Mariana, additional, Nérida Sánchez-Rodríguez, Esther, additional, Cardona-Muñóz, Ernesto G., additional, García-Benavides, Leonel, additional, and Grover-Páez, Fernando, additional

Published
2019
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180. Ligand-inducible, prostate stem cell antigen (PSCA)-directed GoCAR-T cells in advanced solid tumors: Preliminary results from a dose escalation.

Author

Becerra, Carlos Roberto, primary, Hoof, Pamela, additional, Paulson, Andrew Scott, additional, Manji, Gulam Abbas, additional, Gardner, Olivia, additional, Malankar, Aditya, additional, Shaw, Joanne, additional, Blass, Devin, additional, Ballard, Brandon, additional, Yi, Xiaohui, additional, Anumula, Madhavi, additional, Foster, Aaron E., additional, Senesac, Joseph, additional, and Woodard, Paul, additional

Published
2019
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181. A phase I/II multicenter study of ABI-009 (nab-sirolimus) combined with FOLFOX and bevacizumab as first-line (1L) therapy in patients (pts) with metastatic colorectal cancer (mCRC) with or without PTEN loss.

Author

Sharma, Sunil, primary, Becerra, Carlos Roberto, additional, Matrana, Marc Ryan, additional, Alistar, Angela Tatiana, additional, Chiorean, E. Gabriela, additional, Schmid, Anita Nagypal, additional, Grigorian, Berta, additional, Hou, Shihe, additional, and Desai, Neil, additional

Published
2019
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183. Edulab: diseño de una estrategia educativa basada en las prácticas de la cultura digital

Author

Gómez Palacio, Jhon Estiwar, Betacurth Becerra, Carlos Mario, Gómez Palacio, Jhon Estiwar, and Betacurth Becerra, Carlos Mario

Abstract

Este documento da cuenta de la investigación sobre los Laboratorios Educativos EDULABS que inició en la Universidad Tecnológica de Pereira durante el año 2017. La investigación aborda temas alrededor de la cibercultura como un escenario de transformaciones que implican pensar en el uso e implementación de las tecnologías en los espacios educativos; las tensiones que generan, los antecedentes latinoamericanos sobre tecnologías educativas, la apropiación tecnológica como una condición para ir más allá del uso y la comunicación educativa como un campo de reflexión constituyen el tema de investigación. A partir de la metodología de Pensamiento de Diseño para Educadores de la Universidad de Stanford, se propone diseñar una estrategia educativa basada en laboratorios, a partir de tres momentos claves; 1. Observar como una forma en la cual se puede comprender a las personas para co-diseñar una solución a la pregunta de investigación; 2. Diseño, donde se realizan actividades como mapas de afinidades, definición de criterios para el diseño de la estrategia; y 3. Implementación y evaluación, donde se describen las actividades que se proponen dentro de la estrategia y los resultados en cuanto a la implementación.

Published
2019

184. Sepsis neonatal: aspectos fisiopatológicos y biomarcadores

Author

Cortés, José S., Fernández Cruz, Laura X., Beltrán Zúñiga, Emilce, Narváez, Carlos F., Fonseca Becerra, Carlos Eduardo, Cortés, José S., Fernández Cruz, Laura X., Beltrán Zúñiga, Emilce, Narváez, Carlos F., and Fonseca Becerra, Carlos Eduardo

Abstract

Neonatal sepsis is a major cause of morbidity and mortality in newborns worldwide. Its diagnosis remains a challenge due to the nonspecific clinical findings and the lack of efficient diagnostic tools. In the physiopathology of neonatal sepsis, an excessive or suppressed immune response has been described, which can lead to potentially fatal conditions. The prognostic, diagnostic, and follow-up value of several soluble factors altered in neonatal sepsis has been studied. These have been grouped under the term neonatal sepsis biomarkers. Here, aspects of the physiopathology in neonatal sepsis and the characteristics of the most studied biomarkers used for neonatal sepsis diagnosis are described, also, details about other recently studied markers are mentioned. Currently, the use of an early-warning biomarker together with a late-warning biomarker is recommended to get higher diagnostic accuracy. However, a single ideal biomarker for neonatal sepsis has not been found yet. MÉD.UIS.2019;32(3):35-47, La sepsis neonatal es una causa importante de morbilidad y mortalidad en recién nacidos a nivel mundial. Su diagnóstico es difícil por sus manifestaciones clínicas inespecíficas y la poca disponibilidad de métodos diagnósticos eficientes. En la fisiopatología de la sepsis se ha descrito una respuesta inmune excesiva o suprimida que puede conducir a desenlaces potencialmente fatales. Se ha estudiado la utilidad pronóstica, diagnóstica y de seguimiento de factores solubles que se alteran en la sepsis neonatal y se han agrupado bajo el término biomarcadores de sepsis neonatal. Aquí se describen los principios fisiopatológicos de la sepsis neonatal y las características de los biomarcadores más usados para su diagnóstico, además, se mencionan detalles de otros marcadores que también han sido estudiados recientemente. Actualmente, se recomienda el uso de un biomarcador temprano en combinación con uno tardío para lograr un mejor rendimiento, sin embargo, aún no se ha identificado un biomarcador ideal para la sepsis neonatal. MÉD.UIS.2019;32(3):35-47

Published
2019

185. Alteraciones del neurodesarrollo en pacientes con hipotiroidismo congénito: Recomendaciones para el seguimiento

Author

Núñez, Alicia, Bedregal, Paula, Becerra, Carlos, and Grob L., Francisca

Subjects
Neurodevelopmental Disorders, Congenital Hypothyroidism, Cognitive Dysfunction
Abstract

Congenital hypothyroidism (CH) is the most common cause of preventable cognitive disability worldwide. Generally, it is produced by an alteration in the embryogenesis of the thyroid gland or by an alteration in the synthesis of thyroid hormones, which determine that affected patients have low or absent thyroid hormone concentrations. The importance of this fact is that brain development during the first three years of life is highly dependent on thyroid hormones. Prior to the implementation of national neonatal screening programs around the world, 8 to 27% of children with CH had an IQ lower than 70. Nowadays, this percentage is close to 0 in countries that have implemented the program. In Chile, CH neonatal screening program achieved national coverage in 1996. Currently, the incidence of the disease in our country is 1: 3163. The degree of disability produced by CH not only depends on the time of detection of the disease and the prompt start of therapy, but also on an adequate monitoring. Despite screening programs, neurocognitive impairment in schoolchildren and teenagers with CH is still observed, reflected in lower scores in cognitive, language and gross motor assessments, receptive communication, expressive communication, fine motor and gross motor skills compared to healthy children. Also, lesser achievements in learning and language disorders are observed. The objective of this review is to update the information available on neurodevelopment of patients with CH.

Published
2017

186. Disease duration of rheumatoid arthritis is a predictor of vascular stiffness: a cross-sectional study in patients without known cardiovascular comorbidities

Author

Vázquez-Del Mercado, Mónica, Gomez-Bañuelos, Eduardo, Chavarria-Avila, Efrain, Cardona-Muñoz, Ernesto, Ramos-Becerra, Carlos, Alanis-Sanchez, Adrián, Cardona-Muller, David, Grover-Paez, Fernando, Perez-Vazquez, Felipe de J., Navarro-Hernandez, Rosa-Elena, Valadez-Soto, Jorge M., Saldaña-Millan, Adan A., Gonzalez-Rosas, Lorena, Ramos-Lopez, Gabriel, Petri, Marcelo H., and Bäck, Magnus

Subjects
rheumatoid arthritis, Adult, Manometry, Age Factors, Observational Study, Middle Aged, Pulse Wave Analysis, subclinical cardiovascular disease, Lipids, Peptides, Cyclic, Severity of Illness Index, Arthritis, Rheumatoid, Femoral Artery, arterial stiffness, Carotid Arteries, Cross-Sectional Studies, Vascular Stiffness, vascular aging, Rheumatoid Factor, Risk Factors, Humans, Age of Onset, carotid to femoral pulse wave velocity, Research Article
Abstract

The aim of this study was to analyze the impact of disease duration on carotid to femoral pulse wave velocity (cfPWV) in rheumatoid arthritis (RA) patients without either known traditional cardiovascular risk factors or previous comorbidities. Patients with RA diagnosis attending the rheumatology outpatient clinic of Hospital Civil Juan I. Menchaca, Guadalajara, Mexico, were analyzed. A total of 106 RA patients without known traditional cardiovascular risk factors were selected. All subjects were evaluated for RA disease duration, RA disease activity score on 28 joints (DAS28), serum lipids, rheumatoid factor and anti-cyclic citrullinated peptide (anti-CCP) antibodies. Arterial stiffness was measured as cfPWV by noninvasive tonometry. A multivariate regression model was used to analyze the contribution of RA disease duration and age on cfPWV. cfPWV was positively correlated with age (r = 0.450, P

Published
2017

188. Análisis de la generación de rentas propias por el municipio de Ocaña en el periodo 2009-2017.

Author

Andrés Sánchez-Becerra, Carlos and Mauricio-Rodríguez, Alex

Subjects
DECENTRALIZATION in government, MUNICIPAL finance, TAX collection, FEDERAL government, LOCAL taxation, FINANCE, GOVERNMENT accounting
Abstract

Copyright of CLIO América is the property of Universidad del Magdalena and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2020
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189. Síndrome de dificultad respiratoria aguda neonatal.

Author

Luis Sánchez, Jorge, Suaza-Vallejo, Camila, Felipe Reyes-Vega, Daniel, and Fonseca-Becerra, Carlos

Abstract

Copyright of Revista Mexicana de Pediatria is the property of Sociedad Mexicana de Pediatria and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2020
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190. Subclinical parameters of arterial stiffness and arteriosclerosis correlate with QRISK3 in systemic lupus erythematosus

Author

Vázquez-Del Mercado, Mónica, primary, Perez-Vazquez, Felipe de J., additional, Gomez-Bañuelos, Eduardo, additional, Chavarria-Avila, Efrain, additional, Llamas-García, Arcelia, additional, Arrona-Rios, Karla I., additional, Diaz-Rubio, Gustavo Ignacio, additional, Durán-Barragán, Sergio, additional, Navarro-Hernández, Rosa E., additional, Jordán-Estrada, Bethel P., additional, Prado-Bachega, Natalia, additional, Gonzalez-Beltran, Miguel A. A., additional, Ramos-Becerra, Carlos, additional, Grover-Paez, Fernando, additional, Cardona-Müller, David, additional, and Cardona-Muñoz, Ernesto G., additional

Published
2018
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193. Pembrolizumab versus paclitaxel for previously treated, advanced gastric or gastro-oesophageal junction cancer (KEYNOTE-061): a randomised, open-label, controlled, phase 3 trial

Author

Shitara, Kohei, primary, Özgüroğlu, Mustafa, additional, Bang, Yung-Jue, additional, Di Bartolomeo, Maria, additional, Mandalà, Mario, additional, Ryu, Min-Hee, additional, Fornaro, Lorenzo, additional, Olesiński, Tomasz, additional, Caglevic, Christian, additional, Chung, Hyun C, additional, Muro, Kei, additional, Goekkurt, Eray, additional, Mansoor, Wasat, additional, McDermott, Raymond S, additional, Shacham-Shmueli, Einat, additional, Chen, Xinqun, additional, Mayo, Carlos, additional, Kang, S Peter, additional, Ohtsu, Atsushi, additional, Fuchs, Charles S, additional, Lerzo, Guillermo, additional, O'Connor, Juan Manuel, additional, Mendez, Guillermo Ariel, additional, Lynam, James, additional, Tebbutt, Niall, additional, Wong, Mark, additional, Strickland, Andrew, additional, Karapetis, Chris, additional, Goldstein, David, additional, Vasey, Paul, additional, Van Laethem, Jean-Luc, additional, Van Cutsem, Eric, additional, Berry, Scott, additional, Vincent, Mark, additional, Muller, Bettina, additional, Rey, Felipe, additional, Zambrano, Angela, additional, Guerra, Joaquin, additional, Krogh, Merete, additional, Baeksgaard, Lene, additional, Yilmaz, Mette, additional, Elme, Anneli, additional, Magi, Andrus, additional, Auvinen, Paivi, additional, Alanko, Tuomo, additional, Moehler, Markus, additional, Kunzmann, Volker, additional, Seufferlein, Thomas, additional, Thuss-Patience, Peter, additional, Hoehler, Thomas, additional, Haag, Georg, additional, Al-Batran, Salah-Eddin, additional, Castro, Hugo, additional, Lopez, Karla, additional, Aguilar Vasquez, Mynor, additional, Sandoval, Mario, additional, Lam, Ka On, additional, Cuffe, Sinead, additional, Kelly, Cathy, additional, Geva, Ravit, additional, Hubert, Ayala, additional, Beny, Alex, additional, Brenner, Baruch, additional, Giuseppe, Aprile, additional, Falcone, Alfredo, additional, Maiello, Evaristo, additional, Passalacqua, Rodolfo, additional, Montesarchio, Vincenzo, additional, Hara, Hiroki, additional, Chin, Keisho, additional, Nishina, Tomohiro, additional, Komatsu, Yoshito, additional, Machida, Nozumo, additional, Hironaka, Shuichi, additional, Satoh, Taroh, additional, Tamura, Takao, additional, Sugimoto, Naotaoshi, additional, Cho, Haruhiko, additional, Omuro, Yashushi, additional, Kato, Ken, additional, Goto, Masahiro, additional, Hyodo, Ichinosuke, additional, Yoshida, Kazuhiro, additional, Baba, Hideo, additional, Esaki, Taito, additional, Furuse, Junji, additional, Wan Mohammed, Wan Zamaniah, additional, Hernandez Hernandez, Carlos, additional, Casas Garcia, Juan, additional, Dominguez Andrade, Adriana, additional, Clarke, Katriona, additional, Hjortland, Geir, additional, Glenjen, Nils, additional, Kubiatowski, Tomasz, additional, Jacek, Jassem, additional, Wojtukiewicz, Marek, additional, Lazarev, Sergey, additional, Lancukhay, Yuri, additional, Afanasayev, Sergey, additional, Moiseyenko, Vladimir, additional, Kostorov, Vladimir, additional, Protsenko, Svetlana, additional, Shirinkin, Vadim, additional, Sakaeva, Dina, additional, Fadeeva, Natalia, additional, Yong, Wei Peng, additional, Ng, Chau Hsien Matthew, additional, Robertson, Barbara, additional, Rapaport, Bernardo, additional, Cohen, Graham, additional, Dreosti, Lydia, additional, Ruff, Paul, additional, Jacobs, Conrad, additional, Landers, Gregory, additional, Szpak, Waldemar, additional, Roh, Sang-Young, additional, Lee, Jeeyun, additional, Kim, Yeul Hong, additional, Chung, Hyun Cheol, additional, Alsina Maqueda, Maria, additional, Longo Munoz, Federico, additional, Cervantes Aguilar, Andres, additional, Aranda Aguilar, Enrique, additional, Garcia Alfonso, Pilar, additional, Rivera, Fernando, additional, Feliu Batle, Jaime, additional, Pazo Cid, Roberto, additional, Yeh, Kun-Huei, additional, Chen, Jen-Shi, additional, Chao, Yee, additional, Yen, Chia-Jui, additional, Kara, Oguz, additional, Yalcin, Suayib, additional, Hochhauser, Daniel, additional, Chau, Ian, additional, Benson, Al, additional, Shankaran, Veena, additional, Shaib, Walid, additional, Philip, Philip, additional, Sharma, Vivek, additional, Siegel, Robert, additional, Sun, Weijing, additional, Wainberg, Zev, additional, George, Ben, additional, Bullock, Andrea, additional, Myrick, Samuel, additional, Faruol, Josephine, additional, Siegel, Richard, additional, Larson, Timothy, additional, Becerra, Carlos, additional, Ratnam, Suresh, additional, Richards, Donald A., additional, and Riche, Stephen L., additional

Published
2018
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196. Evaluation of pharmacodynamic (PD) biomarkers in patients with metastatic pancreatic cancer treated with BL-8040, a novel CXCR4 antagonist.

Author

Hidalgo, Manuel M., primary, Epelbaum, Ron, additional, Semenisty, Valeriya, additional, Geva, Ravit, additional, Golan, Talia, additional, Borazanci, Erkut Hasan, additional, Stemmer, Salomon M., additional, Borad, Mitesh J., additional, Park, Joon Oh, additional, Pedersen, Katrina, additional, Wolpin, Brian M., additional, Ramirez, Robert A., additional, Becerra, Carlos, additional, Shaw, Steven, additional, Oberkovitz, Galia, additional, Vainstein Haras, Abi, additional, Sorani, Ella, additional, Lustig, Tzipora M, additional, Peled, Amnon, additional, and Von Hoff, Daniel D., additional

Published
2018
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198. Confiabilidad de un monitor automatizado para la medición de la presión arterial

Author

Cardona-Müller, David, primary, Grover-Páez, Fernando, additional, Guzmán-Saldivar, Víctor, additional, Alanis-Sánchez, Guillermo A., additional, Murguía-Soto, César, additional, Totsuka-Sutto, Sylvia E., additional, Quezada-Fernández, Patricia, additional, Macías-Chumacera, Agustín, additional, Cardona-Muñoz, Ernesto G., additional, and Ramos-Becerra, Carlos G., additional

Published
2018
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199. Development of memantine orodispersible tablets and their in vitro description and biopharmaceutical performance

Author

Peñaloza-Becerra, Carlos Adrián, primary, Marcelín-Jimenez, Gabriel, additional, López-González, Mariel Vanessa, additional, Ortega-Escamilla, Ernesto, additional, Vásquez-Vásquez, Juan Ernesto, additional, Ángeles-Moreno, Alionka P, additional, García-González, Alberto, additional, Batista-Dieguez, Dany, additional, and Rodarte-Valle, Estefanía, additional

Published
2018
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200. Mejoramiento del proceso productivo del cuy en el área de producción de la Empresa Cuy´s peruvian a través de la implementación de la metodología lean manufacturing en el año 2017 (Trabajo de Investigación Parcial)

Author

Cacho Chávez, Ena Mirella, Cacho Gonzáles, Wilson Ricardo, Romero Becerra, Carlos Humberto, Cacho Chávez, Ena Mirella, Cacho Gonzáles, Wilson Ricardo, and Romero Becerra, Carlos Humberto

Abstract

El presente trabajo surge de la necesidad de mejorar el proceso productivo en la producción tecnificada de cuyes, utilizando herramientas de manufactura esbelta para optimizar sus procesos y garantizar su supervivencia en el mercado. El objetivo de esta investigación es analizar la situación actual de la empresa, proponer la implementación de las herramientas de manufactura que le permita mejorar la calidad de cuy para su comercialización, reducir el tiempo de entrega y responder de manera rápida a las necesidades cambiantes del cliente para así poder mejorar su competitividad en el mercado y la satisfacción del cliente. El trabajo de investigación empieza con una breve descripción de la empresa Cuy´s Peruvian, los productos que ofrece, los procesos necesarios para la producción de cuyes y los principales indicadores del área de producción. Luego de identificar los principales procesos productivos, se priorizo herramientas de manufactura esbelta 5S’s y uno de los pilares más importantes del TPM, el mantenimiento autónomo, para así poder eliminar los principales desperdicios identificados de manera sistemática. Se evaluó el impacto económico usando herramientas seleccionadas, identificación de costos y beneficio económico que brindará a la empresa. Finalmente, se expondrán conclusiones y recomendaciones para la correcta implementación de las herramientas mencionadas. PALABRAS CLAVES: Implementación, Lean Manufacturing, proceso productivo

Published
2018

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