997 results on '"Baranova, E."'
Search Results
152. Deterministic Approach to Analysis of the Separating Capacity of a Cylindrical-Conical Hydrocyclone
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Lagutkin, M. G., Baranov, D. A., Bulychev, S. Yu., and Baranova, E. Yu.
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- 2004
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153. A Point Mutation in the Coat Protein Gene Affects Long-Distance Transport of the Tobacco Mosaic Virus
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Koshkina, T. E., Baranova, E. N., Usacheva, E. A., and Zavriev, S. K.
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- 2003
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154. Mechanism of Electrodeposition of Lead Dioxide from Nitrate Solutions
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Velichenko, A. B., Baranova, E. A., Girenko, D. V., Amadelli, R., Kovalev, S. V., and Danilov, F. I.
- Published
- 2003
- Full Text
- View/download PDF
155. Expression Analysis of Proteins Encoded by Genes of the tag7/tagL (PGRP-S, L) Family in Human Peripheral Blood Cells
- Author
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Kibardin, A. V., Mirkina, I. I., Zakeyeva, I. R., Baranova, E. V., Georgiev, G. P., and Kiselev, S. L.
- Published
- 2003
- Full Text
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156. Oxygen evolution on lead dioxide modified with fluorine and iron
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Velichenko, A. B., Girenko, D. V., Nikolenko, N. V., Amadelli, R., Baranova, E. A., and Danilov, F. I.
- Published
- 2000
- Full Text
- View/download PDF
157. Macrokinetics of electrolysis of dilute solutions in systems with a solid polymer electrolyte
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Koshel’, N. D., Grebenyuk, Yu. V., and Baranova, E. A.
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- 2000
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158. Genetic damage in lymphocytes of lung cancer patients is correlated to the composition of the respiratory tract microbiome
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Druzhinin, V G, primary, Matskova, L V, additional, Demenkov, P S, additional, Baranova, E D, additional, Volobaev, V P, additional, Minina, V I, additional, Larionov, A V, additional, Titov, V A, additional, and Fucic, A, additional
- Published
- 2021
- Full Text
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159. Triphasic waves on electroencephalogram in patients with encephalopathy and their diagnosis significance. A review
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Baranova, E. A., primary and Sinkin, M. V., additional
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- 2021
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160. Coronavirus disease 2019 in a patient with CADASIL syndrome: a case report
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Zaslavskaya, E. L., primary, Zaslavsky, L. G., additional, Baranova, E. I., additional, Alekseeva, A. M., additional, Markov, N. V., additional, and Zagidullin, N. Sh., additional
- Published
- 2021
- Full Text
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161. The developmental stages passage of Cameraria ohridella under the damage to Aesculus hippocastanum L. may be affected by lighting conditions
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Bogoutdinova, L. R., primary, Konovalova, L. N., additional, and Baranova, E. N., additional
- Published
- 2021
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162. Specific cytochromes P450 and adrenodoxin-like mitochondrial ferredoxins as components of the progesterone hormone system of higher plants involved in comprehensive protection from biotic and abiotic stresse
- Author
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Shpakovski, D. G., primary, Shematorova, E. K., additional, Babak, O. G., additional, Slovokhotov, I. Yu., additional, Spivak, S. G., additional, Khaliluev, M. R., additional, Doludin, Yu. V., additional, Klykov, V. N., additional, Baranova, E. N., additional, Tereshonkova, T. A., additional, Kilchevsky, A. V., additional, and Shpakovski, G. V., additional
- Published
- 2020
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163. Identification of periodontal pathogens in subgingival samples of chronic periodontitis patients with early atherosclerosis
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Baranova, E., primary, Urazgildeeva, S.A., additional, Shugurova, I., additional, Muzalevskaya, M.V., additional, Konovalova, T., additional, Tregubov, A.V., additional, Shurygina, V., additional, and Gurevich, V.S., additional
- Published
- 2020
- Full Text
- View/download PDF
164. Associations of higher blood pressure levels with dyslipidemia in the Russian population: The Russian epidemiology survey ESSE-RF
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Erina, A., primary, Alieva, A.S., additional, Rotar, O., additional, Baranova, E., additional, Konradi, A., additional, Shalnova, S.A., additional, Deev, A.D., additional, Boytsov, S.A., additional, and Shlyakhto, E., additional
- Published
- 2020
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165. ABCA1 and ABCG1 gene expression in subcutaneous and visceral adipose tissue of women with metabolic syndrome
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Miroshnikova, V., primary, Panteleeva, A., additional, Pobozheva, I., additional, Brovin, D., additional, Razgildina, N., additional, Dracheva, K., additional, Polyakova, E., additional, Belyaeva, O., additional, Berkovich, O., additional, Baranova, E., additional, and Pchelina, S., additional
- Published
- 2020
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166. Inflammatory associated microRNAs expression in cardiomyocytes and blood serum in CAD patients
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Polyakova, E, primary, Zaraiskii, M, additional, Baranova, E, additional, and Shlyakhto, E, additional
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- 2020
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167. Resolution of the International meeting of experts on the exchange of scientific experience in the use of anticoagulants in patients with COVID-19
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Avdeev, S. N., primary, Bazarova, A. V., additional, Baranova, E. I., additional, Esayan, A. M., additional, Zhusupova, G. K., additional, Zamyatin, M. N., additional, Zotova, I. V., additional, Kasenova, S. L., additional, Matskeplishvili, S. T., additional, Miller, O. N., additional, Pak, A. M., additional, Salukhov, V. V., additional, Tyrenko, V. V., additional, Khasanova, D. R., additional, Shamalov, N. A., additional, and Yanishevsky, S. N., additional
- Published
- 2020
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168. Wytyczne ESC/ESH dotyczace postȩpowania w nadciśnieniu tȩtniczym (2018): Grupa Robocza Europejskiego Towarzystwa Kardiologicznego (ESC) i Europejskiego Towarzystwa Nadciśnienia Tȩtniczego (ESH) do spraw postȩpowania w nadciśnieniu tȩtniczym
- Author
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Williams B., Mancia G., Spiering W., Rosei E. A., Azizi M., Burnier M., Clement D. L., Coca A., De Simone G., Dominiczak A., Kahan T., Mahfoud F., Redon J., Ruilope L., Zanchetti A., Kerins M., Kjeldsen S. E., Kreutz R., Laurent S., Lip G. Y. H., McManus R., Narkiewicz K., Ruschitzka F., Schmieder R. E., Shlyakhto E., Tsioufis C., Aboyans V., Desormais I., Windecker S., Agewall S., Barbato E., Bueno H., Collet J. -P., Coman I. M., Dean V., Delgado V., Fitzsimons D., Gaemperli O., Hindricks G., Iung B., Juni P., Katus H. A., Knuuti J., Lancellotti P., Leclercq C., McDonagh T. A., Piepoli M. F., Ponikowski P., Richter D. J., Roffi M., Simpson I. A., Sousa-Uva M., Zamorano J. L., Lurbe E., Bochud M., Jelakovic B., Januszewicz A., Polonia J., Van De Borne P., Borghi C., Parati G., Manolis A., Lovic D., Benkhedda S., Zelveian P., Siostrzonek P., Najafov R., Pavlova O., De Pauw M., Dizdarevic-Hudic L., Raev D., Karpettas N., Olsen M. H., Shaker A. F., Viigimaa M., Baranova E. I., Metsarinne K., Halimi J. -M., Pagava Z., Thomopoulos C., Bertomeu-Martinez V., Wittekoek J., Andersen K., Shechter M., Romanova T., Bajraktari G., Saade G. A., Sakalyte G., Noppe S., Trusinskis K., Vavlukis M., DeMarco D. C., Caraus A., Schunkert H., Aksnes T. A., Jankowski P., Linhart A., Vinereanu D., Foscoli M., Dikic A. D., Filipova S., Fras Z., Burkard T., Carlberg B., Sdiri W., Aydogdu S., Sirenko Y., Pall D., Brady A., Mercuro G., Weber T., Lazareva I., De Backer T., Sokolovic S., Chazova I., Porsti I., Denolle T., Stergiou G. S., Segura J., Miglinas M., Kramer B. K., Gerdts E., Tykarski A., De Carvalho Rodrigues M., Widimsky J., Dorobantu M., Brguljan J., Pechere-Bertschi A., Gottsater A., Erdine S., Williams, B, Mancia, G, Spiering, W, Rosei, E, Azizi, M, Burnier, M, Clement, D, Coca, A, De Simone, G, Dominiczak, A, Kahan, T, Mahfoud, F, Redon, J, Ruilope, L, Zanchetti, A, Kerins, M, Kjeldsen, S, Kreutz, R, Laurent, S, Lip, G, Mcmanus, R, Narkiewicz, K, Ruschitzka, F, Schmieder, R, Shlyakhto, E, Tsioufis, C, Aboyans, V, Desormais, I, Windecker, S, Agewall, S, Barbato, E, Bueno, H, Collet, J, Coman, I, Dean, V, Delgado, V, Fitzsimons, D, Gaemperli, O, Hindricks, G, Iung, B, Juni, P, Katus, H, Knuuti, J, Lancellotti, P, Leclercq, C, Mcdonagh, T, Piepoli, M, Ponikowski, P, Richter, D, Roffi, M, Simpson, I, Sousa-Uva, M, Zamorano, J, Lurbe, E, Bochud, M, Jelakovic, B, Januszewicz, A, Polonia, J, Van De Borne, P, Borghi, C, Parati, G, Manolis, A, Lovic, D, Benkhedda, S, Zelveian, P, Siostrzonek, P, Najafov, R, Pavlova, O, De Pauw, M, Dizdarevic-Hudic, L, Raev, D, Karpettas, N, Olsen, M, Shaker, A, Viigimaa, M, Baranova, E, Metsarinne, K, Halimi, J, Pagava, Z, Thomopoulos, C, Bertomeu-Martinez, V, Wittekoek, J, Andersen, K, Shechter, M, Romanova, T, Bajraktari, G, Saade, G, Sakalyte, G, Noppe, S, Trusinskis, K, Vavlukis, M, Demarco, D, Caraus, A, Schunkert, H, Aksnes, T, Jankowski, P, Linhart, A, Vinereanu, D, Foscoli, M, Dikic, A, Filipova, S, Fras, Z, Burkard, T, Carlberg, B, Sdiri, W, Aydogdu, S, Sirenko, Y, Pall, D, Brady, A, Mercuro, G, Weber, T, Lazareva, I, De Backer, T, Sokolovic, S, Chazova, I, Porsti, I, Denolle, T, Stergiou, G, Segura, J, Miglinas, M, Kramer, B, Gerdts, E, Tykarski, A, De Carvalho Rodrigues, M, Widimsky, J, Dorobantu, M, Brguljan, J, Pechere-Bertschi, A, Gottsater, A, and Erdine, S
- Subjects
Antihypertensive Agent ,Cardiology ,Disease Management - Published
- 2019
169. Is cardiotrophin-1 a new risk factor of atrial fibrillation in patients with visceral obesity and metabolic syndrome?
- Author
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Ionin, V. A., primary, Zaslavskaya, E. L., additional, Petrishcheva, E. Y., additional, Barashkova, E. I., additional, Skuridin, D. S., additional, Filatova, А. G., additional, and Baranova, E. I., additional
- Published
- 2020
- Full Text
- View/download PDF
170. Clinical features of atrial fibrillation in obese hypertensives: results of a retrospective observational study
- Author
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Petrischeva, E. Yu, primary, Ionin, V. A, additional, Bliznuk, O. I, additional, Pavlova, V. A, additional, Skuridin, D. S., additional, Ma, I., additional, Borisov, G. I., additional, Zaslavskaya, E. L., additional, and Baranova, E. I., additional
- Published
- 2020
- Full Text
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171. Central directions for reducing cardiovascular mortality: what can be changed today?
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Shlyakhto, E. V., primary and Baranova, E. I., additional
- Published
- 2020
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172. Markers of vascular damage depending on the blood pressure level: data of the population study ESSE-RF
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Erina, A. M., primary, Boyarinova, M. A., additional, Moguchaya, E. V., additional, Kolesova, E. P., additional, Aliyeva, A. S., additional, Rotar, O. P., additional, Baranova, E. I., additional, Shalnova, S. A., additional, Deev, A. D., additional, Astakhova, Z. T., additional, Bolieva, L. Z., additional, Tolparov, G. V., additional, Kaveshnikov, V. S., additional, Serebryakova, V. N., additional, Trubacheva, I. A., additional, Karpov, R. S., additional, Efanov, A. Yu., additional, Storozhok, M. A., additional, Medvedeva, I. V., additional, Shalaev, S. V., additional, Rogoza, A. N., additional, Konradi, A. O., additional, Boytsov, S. A., additional, and Shlyakhto, E. V., additional
- Published
- 2020
- Full Text
- View/download PDF
173. Taxonomic diversity of sputum microbiome in lung cancer patients and its relationship with chromosomal aberrations in blood lymphocytes
- Author
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Druzhinin, V. G., primary, Matskova, L. V., additional, Demenkov, P. S., additional, Baranova, E. D., additional, Volobaev, V. P., additional, Minina, V. I., additional, Apalko, S. V., additional, Churina, M. A., additional, Romanyuk, S. A., additional, Shcherbak, S. G., additional, Ivanov, V. I., additional, and Larionov, A. V., additional
- Published
- 2020
- Full Text
- View/download PDF
174. The crustal structure of the transition from the East Black Sea Basin to the Shatsky Ridge from the reinterpretation of deep seismic sounding data on profiles 14-15-16
- Author
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Baranova, E. P., primary and Yegorova, Т. P., additional
- Published
- 2020
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175. Atrial fibrillation in St Petersburg cohort: frequency, risk factors, antiarrhythmic therapy and thromboembolism prevention
- Author
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Ionin, V. A., primary, Barashkova, E. I., additional, Filatova, A. G., additional, Baranova, E. I., additional, and Shlyakhto, E. V., additional
- Published
- 2020
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- View/download PDF
176. Epicardial and subcutenious adipose tissue adiponectin gene expression in coronary artery disease patients
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Pobozheva, I. A., primary, Razgildina, N. D., additional, Polyakova, E. A., additional, Panteleeva, A. A., additional, Belyaeva, O. D., additional, Nifontov, S. E., additional, Galkina, O. V., additional, Kolodina, D. A., additional, Berkovich, O. A., additional, Baranova, E. I., additional, Pchelina, S. N., additional, and Miroshnikova, V. V., additional
- Published
- 2020
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177. Prognostic value of epicardial fat thickness in coronary heart disease patients after myocardial revascularization
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Polyakova, E. A., primary, Berkovich, O. A., additional, and Baranova, E. I., additional
- Published
- 2020
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178. THE USE OF SYNTHETIC GLYCOCONJUGATES AS COMPONENTS OF THE IMMUNOCHROMATOGRAPHIC TEST FOR RAPID SEROLOGICAL DIAGNOSIS OF LEPROSY
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Korolyova-Ushakova, A. G., primary, Baranova, E. V., additional, Ignatov, S. G., additional, Fedyukina, G. N., additional, Solov’ev, P. V., additional, Kolombet, L. V., additional, and Biketov, S. F., additional
- Published
- 2020
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179. Arterial hypertension in adults. Clinical guidelines 2020
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Kobalava, Zh. D., primary, Konradi, A. O., additional, Nedogoda, S. V., additional, Shlyakhto, E. V., additional, Arutyunov, G. P., additional, Baranova, E. I., additional, Barbarash, O. L., additional, Boitsov, S. A., additional, Vavilova, T. V., additional, Villevalde, S. V., additional, Galyavich, A. S., additional, Glezer, M. G., additional, Grineva, E. N., additional, Grinstein, Yu. I., additional, Drapkina, O. M., additional, Zhernakova, Yu. V., additional, Zvartau, N. E., additional, Kislyak, O. A., additional, Koziolova, N. A., additional, Kosmacheva, E. D., additional, Kotovskaya, Yu. V., additional, Libis, R. A., additional, Lopatin, Yu. M., additional, Nebiridze, D. V., additional, Nedoshivin, A. O., additional, Ostroumova, O. D., additional, Oschepkova, E. V., additional, Ratova, L. G., additional, Skibitsky, V. V., additional, Tkacheva, O. N., additional, Chazova, I. E., additional, Chesnikova, A. I., additional, Chumakova, G. A., additional, Shalnova, S. A., additional, Shestakova, M. V., additional, Yakushin, S. S., additional, and Yanishevsky, S. N., additional
- Published
- 2020
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180. Atrial fibrillation and CHA2DS2VASc score of 1 - is there a problem in clinical practice?
- Author
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Baranova, E. I., primary, Pavlova, V. A., additional, Ionin, V. A., additional, Petrischeva, E. Yu., additional, Bliznuk, O. I., additional, Zaslavskaya, E. L., additional, Ma, I., additional, Skuridin, D. S., additional, and Shlakhto, E. V., additional
- Published
- 2020
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181. Variations of methane in the Antarctic atmosphere in 2009–2017 by ground-based and satellite data
- Author
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Ustinov, V. P., primary, Baranova, E. L., additional, Visheratin, K. N., additional, Grachev, M. I., additional, and Kalsin, A. V., additional
- Published
- 2020
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182. Hopping conductivity in polycrystalline photoconductive Pb3O4 layers
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Avanesyan, V. T., Potachev, S. A., and Baranova, E. P.
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- 2009
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183. The role of raas system in patients with abdominal obesity and arterial hypertension: PO20167
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Bazhenova, E A, Berezina, A V, Belyaeva, O D, Lukina, A E, Karavani, A V, Karonova, T L, Nikolaychuk, E I, Berkovich, O A, Baranova, E I, and Shlyakhto, E V
- Published
- 2010
184. Infralow-frequency dielectric response of Pb3O4 polycrystalline layers
- Author
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Avanesyan, V. T., Baranova, E. P., and Grabko, G. I.
- Published
- 2008
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185. Kinetics of polarization current in a Pb3O4 wide-gap photoconductor
- Author
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Avanesyan, V. T., Bordovskii, V. A., Baranova, E. P., and Grabko, G. I.
- Published
- 2007
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186. Relaxation of photodielectric effect in Pb3O4 layers
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Avanesyan, V. T. and Baranova, E. P.
- Published
- 2007
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187. Photodielectric effect in polycrystalline layers of Pb3O4
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Avanesyan, V. T. and Baranova, E. P.
- Published
- 2007
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188. Radiation-hard semiconductor detectors for SuperLHC
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Bruzzi, M., Adey, J., Al-Ajili, A., Alexandrov, P., Alfieri, G., Allport, P.P., Andreazza, A., Artuso, M., Assouak, S., Avset, B.S., Barabash, L., Baranova, E., Barcz, A., Basile, A., Bates, R., Belova, N., Biagi, S.F., Bilei, G.M., Bisello, D., Blue, A., Blumenau, A., Boisvert, V., Bolla, G., Bondarenko, G., Borchi, E., Borrello, L., Bortoletto, D., Boscardin, M., Bosisio, L., V. Bowcock, T.J., Brodbeck, T.J., Broz, J., Brukhanov, A., Brzozowski, A., Buda, M., Buhmann, P., Buttar, C., Campabadal, F., Campbell, D., Candelori, A., Casse, G., Cavallini, A., Chilingarov, A., Chren, D., Cindro, V., Citterio, M., Collins, P., Coluccia, R., Contarato, D., Coutinho, J., Creanza, D., Cunningham, W., Cvetkov, V., Dalla Betta, G.-F., Davies, G., Dawson, I., de Boer, W., De Palma, M., Demina, R., Dervan, P., Dierlamm, A., Dittongo, S., Dobrzanski, L., Dolezal, Z., Dolgolenko, A., Eberlein, T., Eremin, V., Fall, C., Fasolo, F., Ferbel, T., Fizzotti, F., Fleta, C., Focardi, E., Forton, E., Franchenko, S., Fretwurst, E., Gamaz, F., Garcia, C., Garcia-Navarro, J.E., Gaubas, E., Genest, M.-H., Gill, K.A., Giolo, K., Glaser, M., Goessling, C., Golovine, V., González Sevilla, S., Gorelov, I., Goss, J., Gouldwell, A., Grégoire, G., Gregori, P., Grigoriev, E., Grigson, C., Grillo, A., Groza, A., Guskov, J., Haddad, L., Härkönen, J., Harding, R., Hauler, F., Hayama, S., Hoeferkamp, M., Hönniger, F., Horazdovsky, T., Horisberger, R., Horn, M., Houdayer, A., Hourahine, B., Hruban, A., Hughes, G., Ilyashenko, I., Irmscher, K., Ivanov, A., Jarasiunas, K., Jin, T., Jones, B.K., Jones, R., Joram, C., Jungermann, L., Kalinina, E., Kaminski, P., Karpenko, A., Karpov, A., Kazlauskiene, V., Kazukauskas, V., Khivrich, V., Khomenkov, V., Kierstead, J., Klaiber-Lodewigs, J., Kleverman, M., Klingenberg, R., Kodys, P., Kohout, Z., Korjenevski, S., Kowalik, A., Kozlowski, R., Kozodaev, M., Kramberger, G., Krasel, O., Kuznetsov, A., Kwan, S., Lagomarsino, S., Lari, T., Lassila-Perini, K., Lastovetsky, V., Latino, G., Latushkin, S., Lazanu, S., Lazanu, I., Lebel, C., Leinonen, K., Leroy, C., Li, Z., Lindström, G., Lindstrom, L., Linhart, V., Litovchenko, A., Litovchenko, P., Litvinov, V., Lo Giudice, A., Lozano, M., Luczynski, Z., Luukka, P., Macchiolo, A., Mainwood, A., Makarenko, L.F., Mandić, I., Manfredotti, C., Marti i Garcia, S., Marunko, S., Mathieson, K., Mozzanti, A., Melone, J., Menichelli, D., Meroni, C., Messineo, A., Miglio, S., Mikuž, M., Miyamoto, J., Moll, M., Monakhov, E., Moscatelli, F., Murin, L., Nava, F., Naoumov, D., Nossarzewska-Orlowska, E., Nummela, S., Nysten, J., Olivero, P., Oshea, V., Palviainen, T., Paolini, C., Parkes, C., Passeri, D., Pein, U., Pellegrini, G., Perera, L., Petasecca, M., Piatkowski, B., Piemonte, C., Pignatel, G.U., Pinho, N., Pintilie, I., Pintilie, L., Polivtsev, L., Polozov, P., Popa, A.I., Popule, J., Pospisil, S., Pucker, G., Radicci, V., Rafí, J.M., Ragusa, F., Rahman, M., Rando, R., Roeder, R., Rohe, T., Ronchin, S., Rott, C., Roy, P., Roy, A., Ruzin, A., Ryazanov, A., Sadrozinski, H.F.W., Sakalauskas, S., Scaringella, M., Schiavulli, L., Schnetzer, S., Schumm, B., Sciortino, S., Scorzoni, A., Segneri, G., Seidel, S., Seiden, A., Sellberg, G., Sellin, P., Sentenac, D., Shipsey, I., Sicho, P., Sloan, T., Solar, M., Son, S., Sopko, B., Spencer, N., Stahl, J., Stavitski, I., Stolze, D., Stone, R., Storasta, J., Strokan, N., Strupinski, W., Sudzius, M., Surma, B., Suuronen, J., Suvorov, A., Svensson, B.G., Tipton, P., Tomasek, M., Troncon, C., Tsvetkov, A., Tuominen, E., Tuovinen, E., Tuuva, T., Tylchin, M., Uebersee, H., Uher, J., Ullán, M., Vaitkus, J.V., Vanni, P., Velthuis, J., Verzellesi, G., Verbitskaya, E., Vrba, V., Wagner, G., Wilhelm, I., Worm, S., Wright, V., Wunstorf, R., Zabierowski, P., Zaluzhny, A., Zavrtanik, M., Zen, M., Zhukov, V., and Zorzi, N.
- Published
- 2005
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189. Comparative analysis of anatomic structure of cotyledons for determining salt and osmotic tolerance of modified plants
- Author
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Baranova, E. N., Gulevich, A. A., Polyakov, V. Yu., and Kharchenko, P. N.
- Published
- 2007
- Full Text
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190. Isotopic Oxygen Exchange Study to Unravel Noble Metal Oxide/Support Interactions: The Case of RuO2 and IrO2 Nanoparticles Supported on CeO2, TiO2 and YSZ
- Author
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Hajar, Y., Boreave, A., Caravaca, A., Vernoux, P., BARANOVA, E., IRCELYON-Catalytic and Atmospheric Reactivity for the Environment (CARE), Institut de recherches sur la catalyse et l'environnement de Lyon (IRCELYON), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
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yttria-stabilized zirconia ,titania ,[CHIM.CATA]Chemical Sciences/Catalysis ,oxygen exchange ,iridium ,ruthenium ,[SDE.ES]Environmental Sciences/Environmental and Society ,isotopes ,metal-support interaction ,ceria - Abstract
SSCI-VIDE+CARE+ABO:ACV:PVE; International audience; The aim of this study is to unravel the mechanism of (noble metal oxide)/(active support) interactions for catalytic purposes. Hence, isotopic oxygen exchange (IOE) tests were performed on Iridium‐ and ruthenium‐based oxides supported on cerium oxide (CeO2), titanium oxide (TiO2), and yttria‐stabilized zirconia (YSZ). IOE tests demonstrated the metal oxide support involvement in the propane oxidation reaction, with YSZ‐based catalysts showing the highest exchange rate of oxygen, while CeO2 and TiO2‐based catalysts had a less diffusion of lattice oxygen in that order. This is related to the presence of extrinsic oxygen vacancies in the YSZ‐based catalysts and the reduction ability of the CeO2 and TiO2 supports. Despite the limitations on oxygen exchange in some of the noble/metal oxide catalysts, their catalytic performance was comparable to the ones that showed a high oxygen exchange. Therefore, active supports results in a higher engagement of oxygen from the support but not in a linear correlation with the catalytic performance of the metal/support.
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- 2020
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191. The ESC ACCA EAPCI EORP acute coronary syndrome ST-elevation myocardial infarction registry
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Zeymer, U., Ludman, P., Danchin, N., Kala, P., Maggioni, A. P., Weidinger, F, P Gale, C, Beleslin, B, Budaj, A, Chioncel, O, Dagres, N, Danchin, N, Emberson, J, Erlinge, D, Glikson, M, Gray, A, Kayikcioglu, M, P Maggioni, A, K Nagy, V, Nedoshivin, A, A-S, Petronio, Roos-Hesselink, J, Wallentin, L, Zeymer, U, Franz, Weidinger, Uwe, Zeymer, Nicolas, Danchin, Peter, Ludman, Peter, Sinnaeve, Petr, Kala, Roberto, Ferrari, Maggioni, Aldo P., Artan, Goda, Parounak, Zelveian, Kiril, Karamfilov, Zuzana, Motovska, Bent, Raungaard, Toomas, Marandi, Sameh Mohamed Shaheen, Rosa-Maria, Lidon, Pasi Paavo Karjalainen, Zviad, Kereselidze, Dimitrios, Alexopoulos, David, Becker, Martin, Quinn, Zaza, Iakobishvili, Hasan, Al-Farhan, Masoumeh, Sadeghi, Roberto, Caporale, Francesco, Romeo, Erkin, Mirrakhimov, Pranas, Serpytis, Andrejs, Erglis, Sasko, Kedev, Matthew Mercieca Balbi, Alice May Moore, Dariusz, Dudek, Jacek, Legutko, Jorge, Mimoso, Gabriel, Tatu-Chitoiu, Sinisa, Stojkovic, Evgeny, Shlyakhto, Khalid, F AlHabib, Matjaz, Bunc, Martin, Studencan, Mohamed Sami Mourali, Gani, Bajraktari, Marème, Konte, Florian, Larras, Elin Folkesson Lefrancq, Souad, Mekhaldi, Cécile, Laroche, Goda, A, Shuka, N, Pavli, E, Tafaj, E, Gishto, T, Dibra, A, Duka, A, Gjana, A, Kristo, A, Knuti, G, Demiraj, A, Dado, E, Hasimi, E, Simoni, L, Siqeca, M, Sisakian, H, Hayrapetyan, H, Markosyan, S, Galustyan, L, Arustamyan, N, Kzhdryan, H, Pepoyan, S, Zirkik, A, D Von Lewinski, Paetzold, S, Kienzl, I, Matyas, K, Neunteufl, T, Nikfardjam, M, Neuhold, U, Mihalcz, A, Glaser, F, Steinwender, C, Reiter, C, Grund, M, Hrncic, D, Hoppe, U, Hammerer, M, Hinterbuchner, L, Hengstenberg, C, G Delle Karth, Lang, I, Winkler, W, Hasun, M, Kastner, J, Havel, C, Derntl, M, Oberegger, G, Hajos, J, Adlbrecht, C, Publig, T, M-C, Leitgeb, Wilfing, R, Jirak, P, C-Y, Ho, Puskas, L, Schrutka, L, Spinar, J, Parenica, J, Hlinomaz, O, Fendrychova, V, Semenka, J, Sikora, J, Sitar, J, Groch, L, Rezek, M, Novak, M, Kramarikova, P, Stasek, J, Dusek, J, Zdrahal, P, Polasek, R, Karasek, J, Seiner, J, Sukova, N, Varvarovsky, I, Lazarák, T, Novotny, V, Matejka, J, Rokyta, R, Volovar, S, Belohlavek, J, Motovska, Z, Siranec, M, Kamenik, M, Kralik, R, Raungaard, B, Ravkilde, J, E Jensen, S, Villadsen, A, Villefrance, K, C Schmidt Skov, Maeng, M, Moeller, K, Hasan-Ali, H, A Ahmed, T, Hassan, M, Elguind, A, M Farouk Ismail, A Ibrahim Abd El-Aal, A El-sayed Gaafar, H Magdy Hassan, M Ahmed Shafie, M Nabil El-khouly, Bendary, A, Darwish, M, Ahmed, Y, Amin, O, Abdelhakim, A, Abosaif, K, Kandil, H, M A, G Galal, E El Hefny, E, M El Sayed, Aly, K, Mokarrab, M, Osman, M, Abdelhamid, M, Mantawy, S, R Ali, M, D Kaky, S, A Khalil, V, M E, A Saraya, Talaat, A, Nabil, M, M Mounir, W, Aransa, K. Mahmoud A., Kazamel, G, Anwar, S, Al-Habbaa, A, M Abd el Monem, Ismael, A, Amin Abu-Sheaishaa, M., M Abd Rabou, M, T M, A Hammouda, Moaaz, M, Elkhashab, K, Ragab, T, Rashwan, A, Rmdan, A, Abdelrazek, G, Ebeid, H, H Soliman Ghareeb, Farag, N, Zaki, M, Seleem, M, Torki, A, Youssef, M, A AlLah Nasser, N, Rafaat, A, Selim, H, M Makram, M, Khayyal, M, Malasi, K, Madkou, A, Kolib, M, Alkady, H, Nagah, A, Yossef, M, Wafa, A, Mahfouz, E, Faheem, G, M Magdy Moris, Ragab, A, Ghazal, M, Mabrouk, A, El-Masry, M, Naseem, M, Samir, S, Marandi, T, Reinmets, J, Allvee, M, Saar, A, Ainla, T, Vaide, A, Kisseljova, M, Pakosta, U, Eha, J, Lotamois, K, Sia, J, Myllymaki, J, Pinola, T, P Karjalainen, P, Paana, P, Mikkelsson, J, Ampio, M, Tsivilasvili, J, Zurab, P, Kereselidze, Z, Agladze, R, Melia, A, Gogoberidze, D, Khubua, N, Totladze, L, Metreveli, I, Chikovani, A, Eitel, I, Pöss, J, Werner, M, Constantz, A, Ahrens, C, Tolksdorf, H, Klinger, S, Sack, S, Heer, T, Lekakis, J, Kanakakis, I, Xenogiannis, I, Ermidou, K, Makris, N, Ntalianis, A, Katsaros, F, Revi, E, Kafkala, K, Mihelakis, E, Diakakis, G, Grammatikopoulos, K, Voutsinos, D, Alexopoulos, D, Xanthopoulou, I, Mplani, V, Foussas, S, Papakonstantinou, N, Patsourakos, N, Dimopoulos, A, Derventzis, A, Athanasiou, K, P Vassilikos, V, Papadopoulos, C, Tzikas, S, Vogiatzis, I, Datsios, A, Galitsianos, I, Koutsampasopoulos, K, Grigoriadis, S, Douras, A, Baka, N, Spathis, S, Kyrlidis, T, Hatzinikolaou, H, G Kiss, R, Becker, D, Nowotta, F, Tóth, K, Szabó, S, Lakatos, C, Jambrik, Z, Ruzsa, J, Ruzsa, Z, Róna, S, Toth, J, A Vargane Kosik, K S, B Toth, G Nagy, G, Ondrejkó, Z, Körömi, Z, Botos, B, Pourmoghadas, M, Salehi, A, Massoumi, G, Sadeghi, M, Soleimani, A, Sarrafzadegan, N, Roohafza, H, Azarm, M, Mirmohammadsadeghi, A, Rajabi, D, Rahmani, Y, Siabani, S, Najafi, F, Hamzeh, B, Karim, H, Siabani, H, Saleh, N, Charehjoo, H, Zamzam, L, Al-Temimi, T, Al-Farhan, H, Al-Yassin, A, Mohammad, A, Ridha, A, Al-Saedi, G, Atabi, N, Sabbar, O, Mahmood, S, Dakhil, Z, F Yaseen, I, Almyahi, M, Alkenzawi, H, Alkinani, T, Alyacopy, A, Kearney, P, Twomey, K, Iakobishvili, Z, Shlomo, N, Beigel, R, Caldarola, P, Rutigliano, D, L Sublimi Saponetti, Locuratolo, N, Palumbo, V, Scherillo, M, Formigli, D, Canova, P, Musumeci, G, Roncali, F, Metra, M, Lombardi, C, Visco, E, Rossi, L, Meloni, L, Montisci, R, Pippia, V, F Marchetti, M, Congia, M, Cacace, C, Luca, G, Boscarelli, G, Indolfi, C, Ambrosio, G, Mongiardo, A, Spaccarotella, C, S De Rosa, Canino, G, Critelli, C, Caporale, R, Chiappetta, D, Battista, F, Gabrielli, D, Marziali, A, Bernabò, P, Navazio, A, Guerri, E, Manca, F, Gobbi, M, Oreto, G, Andò, G, Carerj, S, Saporito, F, Cimmino, M, Rigo, F, Zuin, G, Tuccillo, B, F Scotto di Uccio, L Scotto di Uccio, Lorenzoni, G, Meloni, I, Merella, P, M Polizzi, G, Pino, R, Marzilli, M, Morrone, D, Caravelliorsini, P, Orsini, E, Mosa, S, Piovaccari, G, Santarelli, A, Cavazza, C, Romeo, F, Fedele, F, Mancone, M, Straito, M, Salvi, N, Scarparo, P, Severino, P, Razzini, C, Massaro, G, Cinque, A, Gaudio, C, Barillà, F, Torromeo, C, Porco, L, Mei, M, Lorio, R, Nassiacos, D, Barco, B, Sinagra, G, Falco, L, Priolo, L, Perkan, A, Strana, M, Bajraktari, G, Percuku, L, Berisha, G, Mziu, B, Beishenkulov, M, Abdurashidova, T, Toktosunova, A, Kaliev, K, Serpytis, P, Serpytis, R, Butkute, E, Lizaitis, M, Broslavskyte, M, G Xuereb, R, M Moore, A, M Mercieca Balbi, Paris, E, Buttigieg, L, Musial, W, Dobrzycki, S, Dubicki, A, Kazimierczyk, E, Tycinska, A, Wojakowski, W, Kalanska-Lukasik, B, Ochala, A, Wanha, W, Dworowy, S, Sielski, J, Janion, M, Janion-Sadowska, A, Dudek, D, Wojtasik-Bakalarz, J, Bryniarski, L, Z Peruga, J, Jonczyk, M, Jankowski, L, Klecha, A, Legutko, J, Michalowska, J, Brzezinski, M, Kozmik, T, Kowalczyk, T, Adamczuk, J, Maliszewski, M, Kuziemka, P, Plaza, P, Jaros, A, Pawelec, A, Sledz, J, Bartus, S, Zmuda, W, Bogusz, M, Wisnicki, M, Szastak, G, Adamczyk, M, Suska, M, Czunko, P, Opolski, G, Kochman, J, Tomaniak, M, Miernik, S, Paczwa, K, Witkowski, A, P Opolski, M, D Staruch, A, Kalarus, Z, Honisz, G, Mencel, G, Swierad, M, Podolecki, T, Marques, J, Azevedo, P, A Pereira, M, Gaspar, A, Monteiro, S, Goncalves, F, Leite, L, Mimoso, J, Manuel Lopes dos Santos, W., Amado, J, Pereira, D, Silva, B, Caires, G, Neto, M, Rodrigues, R, Correia, A, Freitas, D, Lourenco, A, Ferreira, F, Sousa, F, Portugues, J, Calvo, J, Almeida, F, Alves, M, Silva, A, Caria, R, Seixo, F, Militaru, C, Ionica, E, Tatu-Chitoiu, G, Istratoaie, O, Florescu, M, Lipnitckaia, E, Osipova, O, Konstantinov, S, Bukatov, V, Vinokur, T, Egorova, E, Nefedova, E, Levashov, S, Gorbunova, A, Redkina, M, Karaulovskaya, N, Bijieva, F, Babich, N, Smirnova, O, Filyanin, R, Eseva, S, Kutluev, A, Chlopenova, A, Shtanko, A, Kuppar, E, Shaekhmurzina, E, Ibragimova, M, Mullahmetova, M, Chepisova, M, Kuzminykh, M, Betkaraeva, M, Namitokov, A, Khasanov, N, Baleeva, L, Galeeva, Z, Magamedkerimova, F, Ivantsov, E, Tavlueva, E, Kochergina, A, Sedykh, D, Kosmachova, E, Skibitskiy, V, Porodenko, N, Litovka, K, Ulbasheva, E, Niculina, S, Petrova, M, Harkov, E, Tsybulskaya, N, Lobanova, A, Chernova, A, Kuskaeva, A, Kuskaev, A, Ruda, M, Zateyshchikov, D, Gilarov, M, Konstantinova, E, Koroleva, O, Averkova, A, Zhukova, N, Kalimullin, D, Borovkova, N, Tokareva, A, Buyanova, M, Khaisheva, L, Pirozhenko, T, Novikova, T, Yakovlev, A, Tyurina, T, Lapshin, K, Moroshkina, N, Kiseleva, M, Fedorova, S, Krylova, L, Duplyakov, D, Semenova, Y, Rusina, A, Ryabov, V, Syrkina, A, Demianov, S, Reitblat, O, Artemchuk, A, Efremova, E, Makeeva, E, Menzorov, M, Shutov, A, Klimova, N, Shevchenko, I, Elistratova, O, Kostyuckova, O, Islamov, R, Budyak, V, Ponomareva, E, U Ullah Jan, M Alshehri, A, Sedky, E, Alsihati, Z, Mimish, L, Selem, A, Malik, A, Majeed, O, Altnji, I, Alshehri, M, Aref, A, Alhabib, K, Aldosary, M, Tayel, S, M Abd AlRahman, N Asfina, K, G Abdin Hussein, Butt, M, N Markovic Nikolic, Obradovic, S, Djenic, N, Brajovic, M, Davidovic, A, Romanovic, R, Novakovic, V, Dekleva, M, Spasic, M, Dzudovic, B, Jovic, Z, Cvijanovic, D, Cvijanovic, S, Ivanov, I, Cankovic, M, Jarakovic, M, Kovacevic, M, Trajkovic, M, Mitov, V, Jovic, A, Hudec, M, Gombasky, M, Sumbal, J, Bohm, A, Baranova, E, Kovar, F, Samos, M, Podoba, J, Kurray, P, Obona, T, Remenarikova, A, Kollarik, B, Verebova, D, Kardosova, G, Studencan, M, Alusik, D, Macakova, J, Kozlej, M, Bayes-Genis, A, Sionis, A, C Garcia Garcia, R-M, Lidon, A Duran Cambra, C Labata Salvador, F Rueda Sobella, J Sans Rosello, M Vila Perales, T Oliveras Vila, M Ferrer Massot, Bañeras, J, Lekuona, I, Zugazabeitia, G, Fernandez-Ortiz, A, A Viana Tejedor, Ferrera, C, Alvarez, V, Diaz-Castro, O, M Agra-Bermejo, R, Gonzalez-Cambeiro, C, Gonzalez-Babarro, E, J Domingo-Del Valle, Royuela, N, Burgos, V, Canteli, A, Castrillo, C, Cobo, M, Ruiz, M, Abu-Assi, E, M Garcia Acuna, J, U., Zeymer, P., Ludman, N., Danchin, P., Kala, A. P., Maggioni, F., Weidinger, STEMI Investigators, Ac, and Spaccarotella, C.
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Registrie ,medicine.medical_specialty ,Acute coronary syndrome ,Registry ,medicine.medical_treatment ,Cardiology ,Reperfusion therapy ,Retrospective Studie ,Medical ,medicine ,Humans ,cardiovascular diseases ,Myocardial infarction ,Registries ,Disease management (health) ,Acute Coronary Syndrome ,Societies, Medical ,Quality of Health Care ,Retrospective Studies ,Acca ,biology ,business.industry ,Health Policy ,Primary percutaneous coronary intervention ,Percutaneous coronary intervention ,Disease Management ,Retrospective cohort study ,medicine.disease ,biology.organism_classification ,primary percutaneous coronary intervention ,registry ,reperfusion therapy ,ST-elevation myocardial infarction ,Cardiac surgery ,Europe ,surgical procedures, operative ,Emergency medicine ,ST Elevation Myocardial Infarction ,Societies ,Cardiology and Cardiovascular Medicine ,business ,Human - Abstract
Aims The Acute Cardiac Care Association (ACCA)–European Association of Percutaneous Coronary Intervention (EAPCI) Registry on ST-elevation myocardial infarction (STEMI) of the EurObservational programme (EORP) of the European Society of Cardiology (ESC) registry aimed to determine the current state of the use of reperfusion therapy in ESC member and ESC affiliated countries and the adherence to ESC STEMI guidelines in patients with STEMI. Methods and results Between 1 January 2015 and 31 March 2018, a total of 11 462 patients admitted with an initial diagnosis of STEMI according to the 2012 ESC STEMI guidelines were enrolled. Individual patient data were collected across 196 centres and 29 countries. Among the centres, there were 136 percutaneous coronary intervention centres and 91 with cardiac surgery on-site. The majority of centres (129/196) were part of a STEMI network. The main objective of this study was to describe the demographic, clinical, and angiographic characteristics of patients with STEMI. Other objectives include to assess management patterns and in particular the current use of reperfusion therapies and to evaluate how recommendations of most recent STEMI European guidelines regarding reperfusion therapies and adjunctive pharmacological and non-pharmacological treatments are adopted in clinical practice and how their application can impact on patients’ outcomes. Patients will be followed for 1 year after admission. Conclusion The ESC ACCA-EAPCI EORP ACS STEMI registry is an international registry of care and outcomes of patients hospitalized with STEMI. It will provide insights into the contemporary patient profile, management patterns, and 1-year outcome of patients with STEMI.
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- 2019
192. Chrysophycean cysts (stomatocysts) from Lake Baikal and Irkutsk Reservoir, Siberia
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Vorobyova, S. S., Pomazkina, G. V., Baranova, E. Yu., Likhoshway, Ye. V., and Sandgren, Craig D.
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- 1996
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193. Prediction of potential antigenic domains of HIV-1 Pol protein and evaluation their immunoreactivity: R2197
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Puzyrev, V., Savelʼeva, N., Baranova, E., Vanʼkova, O., Pimenov, V., Obriadina, A., Burkov, A., and Ulanova, T.
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- 2005
194. Pharmacogenetics: From Bench to Bedside
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Erlich, H., Bonnet, J., Frueh, F. W., Bertrand, P., Schmitz, G., Salvatore, G., Little, S., Lambert, C., Baranova, E., and Siest, G.
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- 2003
195. Assessment of essential oil yield in three mint species in the climatic conditions of Central Russia.
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Shelepova, O. V., Olekhnovich, L. S., Konovalova, L. N., Khusnetdinova, T. I., Gulevich, A. A., and Baranova, E. N.
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ESSENTIAL oils ,PEPPERMINT ,HARVESTING time ,SPECIES ,PLANT physiology - Abstract
The aim of the study was to study the harvest time for the essential oil yield and its qualitative composition in three species of mint Mentha piperita L. (Peppermint), M. spicata L. (Spearmint) and M. arvensis var. piperascens Malinv. ex. Holmes (Sakhalinmint). In 2018, the research was performed with plants of second year of vegetation in the Laboratory of Plant Physiology and Immunity of the NV Tsitsin Main Botanical Garden of the RAS. As a result, it was found that the optimal harvest period for Sakhalinmint and Peppermint should be recommended in a phase of mass flowering: the yield of fresh raw materials was 509-479 g m
-2 , air-dry raw materials - 110-107 gm-2; the content of essential oil in the aboveground part (a mixture of leaves and inflorescences) of plants - 3.24-4.01%; the proportion of the main component of essential oil (menthol) - 57.3-50.2%. In Spearmint, the optimum time for harvesting is the phase of budding. The content of the main component of essential oil (carvon) was maximum - 67.9%, and the yield of essential oil was 2.6%, while the yield was 381 g m-2 of fresh raw materials (81.9 g m-2 of air-dry raw materials) at harvesting in this ontogenesis stage. Analysis of the secretory apparatus parameters on a surface of some green tissues in three mint species showed that the maximum density of secretory glands on both sides of the leaf is characteristic of peppermint, which provides a higher yield of essential oil in this type of mint. The study allowed determining the optimal harvesting time for highly productive mint species when they are grown in the conditions of Central Russia. The raw materials of these mint species can be used for the production of essential oils and are of interest for pharmacology and the perfume and cosmetics industry. [ABSTRACT FROM AUTHOR]- Published
- 2021
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196. Some features of cultivating different Chamaenerion angustifolium (L.) Scop, forms in vitro.
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Egorova, D. A., Molkanova, O. I., Gorbunov, Yu. N., Gulevich, A. A., and Baranova, E. N.
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PLANT regulators ,ORNAMENTAL plants ,VITAMIN C ,PLANT nutrients ,CITRIC acid - Abstract
Chamaenerion angustifolium (L.) Scop, characterized by a wide range of economically useful properties. White-flowered form of Ch. angustifolium (L.) Scop. Is extremely rare in nature. At the same time, it is promising as a source of biologically active substances and as a highly decorative plant. The optimal way to reproduce this form is clonal micropropagation. Methods for obtaining Ch. angustifolium in vitro were developed, as well as the optimal selection timing of starting material for micropropagation was determined. In addition, the effect of a mineral composition of nutrient medium and plant growth regulators on the regeneration of microshoots was studied. The highest values of morphometric parameters were achieved on MS medium (Murashige & Skoog, 1962) supplemented with 0.5 mg L
-1 BAP. The multiplication factor of the lilac-flowered form was 8.4 ± 0.2, of the white-flowered form - 9.2 ± 0.6. Comparative analysis of morphometric parameters during cultivation of Ch. angustifolium showed no significant difference between the lilac-flowered and white-flowered forms. The effect of antioxidants on the growth and development of regenerants has been shown. The most optimal nutrient medium for clonal micropropagation of the lilac-flowered form was MS medium (Murashige & Skoog, 1962) containing 0.5mgL-1 of BAP, 50mgL-1 of ascorbic acid and 50 mg L-1 of citric acids and for micropropagation of the white-flowered form it was the medium, containing 100 mg L-1 PVP. [ABSTRACT FROM AUTHOR]- Published
- 2021
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197. Effects of Alirocumab on Cardiovascular Events After Coronary Bypass Surgery
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Szarek, M, Bhatt, DL, Bittner, VA, Diaz, R, Edelberg, JM, Hanotin, C, Harrington, RA, Jukema, JW, Letierce, A, Moryusef, A, Pordy, R, Lopez, GAR, Roe, MT, White, HD, Zeiher, AM, Steg, PG, Schwartz, GG, Aylward, PE, Drexel, H, Sinnaeve, P, Dilic, M, Goodman, SG, Prieto, JC, Yong, H, Lopez-Jaramillo, P, Pecin, I, Reiner, Z, Ostadal, P, Poulsen, SH, Viigimaa, M, Nieminen, MS, Danchin, N, Chumburidze, V, Tse, HF, Xavier, D, Zahger, D, Valgimigli, M, Kimura, T, Kim, HS, Kim, SH, Erglis, A, Laucevicius, A, Kedev, S, Yusoff, K, Alings, M, Halvorsen, S, Flores, RMC, Sy, RG, Budaj, A, Morais, J, Dorobantu, M, Karpov, Y, Ristic, AD, Chua, T, Murin, J, Fras, Z, Tunon, J, de Silva, HA, Muller, C, Ray, KK, Vogel, R, Chaitman, B, Kelsey, SF, Olsson, AG, Rouleau, JL, Simoons, ML, Alexander, K, Meloni, C, Rosenson, R, Sijbrands, EJG, Alexander, JH, Armaganijan, L, Bagai, A, Bahit, MC, Brennan, JM, Clifton, S, DeVore, AD, Deloatch, S, Dickey, S, Dombrowski, K, Ducrocq, G, Eapen, Z, Endsley, P, Eppinger, A, Hess, CN, Hlatky, MA, Jordan, JD, Knowles, JW, Kolls, BJ, Kong, DF, Leonardi, S, Lillis, L, Maron, DJ, Marcus, J, Mathews, R, Mehta, RH, Mentz, RJ, Moreira, HG, Patel, CB, Pereira, SB, Perkins, L, Povsic, TJ, Puymirat, E, Jones, WS, Shah, BR, Sherwood, MW, Stringfellow, K, Sujjavanich, D, Toma, M, Trotter, C, van Diepen, SFP, Wilson, MD, Yan, ATK, Schiavi, LB, Garrido, M, Alvarisqueta, AF, Sassone, SA, Bordonava, AP, De Lima, AEA, Schmidberg, JM, Duronto, EA, Caruso, OC, Novaretto, LP, Hominal, MA, Montana, OR, Caccavo, A, Vilamajo, OAG, Lorenzatti, AJ, Cartasegna, LR, Paterlini, GA, Mackinnon, IJ, Caime, GD, Amuchastegui, M, Codutti, OR, Jure, HO, Bono, JOE, Hrabar, AD, Vallejos, JA, Rodolfo, AAG, Novoa, F, Patocchi, CA, Zaidman, CJ, Giuliano, ME, Dran, RD, Vico, ML, Carnero, GS, Guzman, PN, Allende, JCM, Brasca, DFG, Labarta, MHB, Nani, S, Blumberg, EDS, Colombo, HR, Liberman, A, Luciardi, HL, Waisman, GD, Berli, MA, Duran, ROG, Cestari, HG, Luquez, HA, Giordano, JA, 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Saporito, W, Marin, JA, Feitosa, GS, Ritt, LEF, de Souza, JA, Costa, F, Souza, WKSB, Reis, HJL, Lopes, RD, Machado, L, Ayoub, JCA, Todorov, GV, Nikolov, FP, Velcheva, ES, Tzekova, ML, Benov, HO, Petranov, SL, Tumbev, HS, Shehova-Yankova, NS, Markov, DT, Raev, DH, Mollov, MN, Kichukov, KN, Ilieva-Pandeva, KA, Gotcheva, NN, Ivanova, R, Mincheva, VM, Lazov, PV, Dimov, BI, Senaratne, M, Stone, J, Kornder, J, Pearce, S, Dion, D, Savard, D, Pesant, Y, Pandey, A, Robinson, S, Gosselin, G, Vizel, S, Hoag, G, Bourgeois, R, Morisset, A, Sabbah, E, Sussex, B, Kouz, S, MacDonald, P, Diaz, A, Michaud, N, Fell, D, Leung, R, Vuurmans, T, Lai, C, Nigro, F, Davies, R, Nogareda, G, Vijayaraghavan, R, Ducas, J, Lepage, S, Mehta, S, Cha, J, Dupuis, R, Fong, P, Rodes-Cabau, J, Fadlallah, H, Cleveland, D, Huynh, T, Bata, I, Hameed, A, Pincetti, C, Potthoff, S, Acevedo, M, Aguirre, A, Vejar, M, Yanez, M, Araneda, G, Fernandez, M, Perez, L, Varleta, P, Florenzano, F, Huidobro, L, Raffo, CA, Olivares, C, Chen, JY, Dong, YG, Huang, WJ, Wang, JZ, Huang, SA, Yao, ZH, Cui, L, Lin, WH, Sun, YM, Wang, JF, Li, JP, Zhang, XL, Zhu, H, Chen, DD, Huang, L, Dong, SH, Su, GH, Xu, B, Su, X, Cheng, XS, Lin, JX, Zong, WX, Li, HM, Feng, Y, Xu, DL, Yang, XC, Ke, YN, Lin, XF, Zhang, Z, Zheng, ZQ, Luo, ZR, Chen, YD, Ding, CH, Zheng, Y, Li, XD, Peng, DQ, Li, Y, Wei, M, Liu, SW, Yu, YH, Qu, BM, Jiang, WH, Zhou, YJ, Zhao, XS, Yuan, ZY, Guo, Y, Xu, XP, Shi, XB, Ge, JB, Fu, GS, Bai, F, Fang, WY, Shou, XL, Yang, XJ, Wang, JA, Jaramillo, N, Vallejo, GS, Botia, DCL, Lopez, RB, De Salazar, DIM, Bonfanti, AJC, Higuera, JD, Silva, SIB, Lozada, HJG, Arroyo, JAC, Mendoza, JLA, Ruiz, RLF, Fernandez, AM, Jatin, FGM, Herazo, AS, Parada, JC, Triana, MAU, Spinar, J, Horak, D, Stasek, J, Alan, D, Machova, V, Linhart, A, Novotny, V, Kaucak, V, Rokyta, R, Naplava, R, Coufal, Z, Adamkova, V, Podpera, I, Zizka, J, Motovska, Z, Marusincova, I, Svab, P, Heinc, P, Kuchar, J, Povolny, P, Raungaard, B, Clemmensen, P, Bang, LE, May, O, 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Shinke, T, Ako, J, Fujii, K, Takahashi, T, Sakamoto, T, Furukawa, Y, Sugino, H, Mano, T, Utsu, N, Ito, K, Haraguchi, T, Ueda, Y, Nishibe, A, Fujimoto, K, Yoon, JH, Park, HS, Chae, IH, Kim, MH, Jeong, MH, Rha, S, Kim, C, Hong, T, Busmane, A, Pontaga, N, Strelnieks, A, Mintale, I, Sime, I, Petrulioniene, Z, Kavaliauskiene, R, Jurgaitiene, R, Sakalyte, G, Slapikas, R, Norkiene, S, Misonis, N, Kibarskis, A, Kubilius, R, Bojovski, S, Lozance, N, Kjovkaroski, A, Doncovska, S, Ong, TK, Kasim, S, Maskon, O, Kandasamy, B, Liew, HB, Mohamed, WMIW, Castillo, AG, Calvillo, JC, Campos, PF, Fragoso, JCN, Llamas, EAB, Gamba, MAA, Madrigal, JC, Salas, LGG, Rosas, EL, Diaz, BG, Vazquez, ES, Ackar, AN, Esperon, GAL, Sanchez, CRM, De Leon, MG, Otero, RS, Salmon, GF, Rios, JAP, Ruiz, JAG, Breedveld, RW, Hoogslag, PAM, Suryapranata, H, Oomen, A, Wiersma, JJ, Van Der Wal, RMA, Van Huysduynen-Monraats, PSH, Karalis, I, Verdel, GJE, Brueren, BRG, Troquay, RPT, Viergever, EP, Al-Windy, NYY, Bartels, GL, 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Miklaszewicz, B, Kubica, J, Lipko, JA, Kostarska-Srokosz, E, Piepiorka, M, Drzewiecka, A, Sciborski, R, Stasiewski, A, Blicharski, T, Bystryk, L, Szpajer, M, Korol, M, Czerski, T, Mirek-Bryniarska, E, Gniot, J, Lubinski, A, Gorny, J, Franek, E, Monteiro, P, Bastos, JM, Pereira, HH, Martins, D, Seixo, F, Mendonca, C, Botelho, A, Minescu, B, Istratoaie, O, Tesloianu, DN, Cristian, G, Podoleanu, CGC, Constantinescu, MCA, Bengus, CM, Militaru, C, Rosu, D, Parepa, IR, Matei, AV, Alexandru, TM, Shvarts, Y, Orlikova, O, Kobalava, Z, Barbarash, OL, Markov, V, Lyamina, N, Gordienko, A, Zrazhevsky, K, Vishnevsky, AY, Gurevich, V, Stryuk, R, Lomakin, NV, Bokarev, I, Shalaev, S, Khaisheva, L, Chizhov, P, Viktorova, I, Osokina, N, Akatova, E, Chumakova, G, Libov, I, Voevoda, MI, Tretyakova, TV, Baranov, E, Shustov, S, Yakushin, S, Gordeev, I, Khasanov, N, Reshetko, O, Sotnikova, T, Molchanova, O, Nikolaev, K, Gapon, L, Baranova, E, Shogenov, Z, Kosmachova, E, Povzun, A, Egorova, L, Tyrenko, VV, Ivanov, IG, Simic, D, Ivanovic, N, Davidovic, G, Tasic, N, Asanin, MR, Stojic, S, Apostolovic, SR, Ilic, S, Putnikovic, B, Stankovic, A, Arandjelovic, A, Radovanovic, S, Balinovac, J, Dincic, DV, Seferovic, P, Dodic, S, Dimkovic, S, Poh, KK, Ong, HY, Micko, K, Nociar, J, Pella, D, Fulop, P, Hranai, M, Palka, J, Mazur, J, Majercak, I, Dzupina, A, Fazekas, F, Gonsorcik, J, Bugan, V, Selecky, J, Kamensky, G, Strbova, J, Smik, R, Dukat, A, Zuran, I, Oklukar, J, Suligoj, NC, Cevc, M, Lipar, L, Cyster, HP, Ranjith, N, Corbett, C, Bayat, J, Makotoko, EM, Kapp, IE, Basson, MMD, Lottering, H, Van Zyl, LJ, Sebastian, PJ, Pillay, T, Saaiman, JA, Commerford, PJ, Cassimjee, S, Ebrahim, IO, Sarvan, M, Mynhardt, JH, Dalby, AJ, Reuter, H, Moodley, R, Vida, M, Fillat, ARC, Peris, VB, Jimenez, FF, Marin, F, Fernandez, JMC, Gil-Extremera, B, Diz, FW, Garcia-Dorado, D, Iniguez, A, Fernandez, JT, Gonzalez-Juanatey, JR, Portales, JF, Murillo, FC, Pericas, LM, Zamorano, JL, Martin, MD, Cortada, JB, Martin, JJA, Fernandez, JRD, Fernandez, JFD, Lledo, JAG, Sales, JC, Rodriguez, JB, Tragant, GG, Benedicto, A, Gonzalez-Juanatey, C, Potau, MC, Perez, IP, De La Tassa, CM, Rincon, PLO, Recena, JB, Escudier, JM, Constantine, G, Haniffa, R, Tissera, N, Amarasekera, S, Fernando, N, Jayawardena, J, Santharaj, W, Ekanayaka, R, Mendis, S, Senaratne, V, Mayurathan, G, Sirisena, T, Rajapaksha, A, Herath, JI, Amarasena, N, Berglund, S, Rasmanis, G, Hagstrom, E, Witt, N, Mourtzinis, G, Nicol, P, Hansen, O, Romeo, S, Torstensson, I, Jensen, SA, Ahremark, U, Sundelin, T, Moccetti, T, Mach, F, Binder, R, Chiang, CE, Tsai, WC, Ueng, KC, Lai, WT, Liu, ME, Hwang, JJ, Yin, WH, Hsieh, IC, Kuo, JY, Huang, TY, Fang, CY, Kaewsuwanna, P, Soonfuang, W, Jintapakorn, W, Sukonthasarn, A, Sritara, P, Wongpraparut, N, Sastravaha, K, Sansanayudh, N, Kehasukcharoen, W, Piyayotai, D, Camsari, A, Kultursay, H, Guneri, S, Mutlu, B, Ersanli, M, Demirtas, M, Kirma, C, Ural, E, Koldas, L, Karpenko, O, Prokhorov, A, Vakaluyk, I, Myshanych, H, Reshotko, D, Batushkin, V, Rudenko, L, Kovalskyi, I, Kushnir, M, Tseluyko, V, Mostovoy, Y, Stanislavchuk, M, Kyiak, Y, Karpenko, Y, Malynovsky, Y, Klantsa, A, Kutniy, O, Amosova, E, Tashchuk, V, Leshchuk, O, Parkhomenko, A, Rishko, M, Kopytsya, M, Yagensky, A, Vatutin, M, Bagriy, A, Barna, OM, Ushakov, O, Dzyak, G, Goloborodko, B, Rudenko, A, Trevelyan, J, Zaman, A, Lee, K, Moriarty, A, Aggarwal, RK, Clifford, P, Wong, YK, Iqbal, SMR, Subkovas, E, Braganza, D, Sarkar, D, Storey, R, Griffiths, H, Mcclure, S, Muthusamy, R, Kurian, J, Levy, T, Barr, C, Kadr, H, Gerber, R, Simaitis, A, Soran, H, Mathur, A, Brodison, A, Oliver, R, Mudawi, T, Reynolds, T, Sharman, D, Butler, R, Wilkinson, P, Lip, GYH, Halcox, J, Vardi, G, Baldari, D, Brabham, D, Treasure, C, Dahl, C, Palmer, B, Wiseman, A, Puri, S, Mohart, AE, Ince, C, Flores, E, Wright, S, Cheng, SC, Rosenberg, M, Rogers, W, Kosinski, E, Forgosh, L, Waltman, J, Khan, M, Shoukfeh, M, Dagher, G, Lieber, I, Kumar, P, East, C, Krichmar, P, White, L, Knickelbine, T, Haldis, T, Gillespie, E, Suh, D, Arif, I, Akhter, F, Carlson, E, D'Urso, M, El-Ahdab, F, Nelson, W, Harris, B, Cohen, S, Carter, L, Sabatino, K, Haddad, T, Malik, A, Rao, S, Mulkay, A, Jovin, I, Klancke, K, Malhotra, V, Devarapalli, SK, Koren, M, Chandna, H, Dodds, G, Janik, M, Moran, J, Sumner, A, Kobayashi, J, Davis, W, Yazdani, S, Pasquini, J, Thakkar, M, Vedere, A, Leimbach, W, Rider, J, Singh, N, Shah, AV, Moriarty, PM, Janosik, D, Pepine, C, Berman, B, Gelormini, J, Daniels, C, Keating, F, Kondo, NI, Shetty, S, Waider, W, Takata, T, Abu-Fadel, M, Shah, V, Aggarwal, R, Izzo, M, Kumar, A, Hattler, B, Link, C, Bortnick, A, Kinzfogl, G, Ghitis, A, Larry, J, Teufel, E, Kuhlman, P, Mclaurin, B, Zhang, WW, Thew, S, Abbas, J, White, M, Ranadive, N, Gring, C, Henderson, D, Schuchard, T, Farhat, N, Kline, G, Mahal, S, Whitaker, J, Speirs, S, Andersen, R, Daboul, N, Horwitz, P, Jafar, Z, Mcgarvey, J, Panchal, V, Voyce, S, Blok, T, Sheldon, W, Azizad, MM, Schmalfuss, C, Picone, M, Herzog, W, Lindsey, J, Nowins, R, Lepor, N, El Shahawy, M, Weintraub, H, Irimpen, A, May, W, Galski, T, Chu, A, Mody, F, Hodes, Z, Fairlamb, J, Lambert, C, Raisinghani, A, Abbate, A, King, M, Carey, C, Gerber, J, Younis, L, Park, H, Vidovich, M, Knutson, T, Friedman, D, Chaleff, F, Loussararian, A, Kimmelstiel, C, Silver, K, Foster, M, Tonnessen, G, Amlani, M, Wali, A, Malozzi, C, Wattanakit, K, O'Donnell, PJ, Singal, D, Jaffrani, N, Banuru, S, Fisher, D, Xenakis, M, Perlmutter, N, Bhagwat, R, Strader, J, Akyea-Djamson, A, Labroo, A, Marais, HJ, Claxton, E, Berk, M, Rossi, P, Joshi, P, Khaira, AS, Kumkumian, G, Lupovitch, S, Purow, J, Welka, S, Hoffman, D, Fischer, S, Soroka, E, Eagerton, D, Pancholy, S, Ray, M, Farrar, M, Pollock, S, French, WJ, Diamantis, S, Gimple, L, Schwartz, S, Pereira, E, Spriggs, D, Strain, J, Vo, A, Chane, M, Hall, J, Vijay, N, Lotun, K, Lester, FM, Nahhas, A, Pope, T, Nager, P, Vohra, R, Bashir, R, Ahmed, H, Berlowitz, M, Fishberg, R, Barrucco, R, Yang, E, Radin, M, Sporn, D, Eisenberg, S, Landzberg, J, Mcgough, M, Turk, S, Schwartz, M, Sundram, PS, Jain, D, Zainea, M, Bayron, C, Karlsberg, R, Lui, H, Keen, W, Westerhausen, D, Khurana, S, Agarwal, H, Birchem, J, Penny, W, Chang, M, Gilbert, JM, Chalavarya, G, Eaton, C, Schmedtje, JF, Christenson, S, Denham, D, Macdonell, A, Gibson, P, Rahman, A, Al Joundi, T, Conrad, G, Kotha, P, Love, M, Giesler, G, Rubenstein, H, Akright, L, Schifferdecker, B, Krawczyk, J, Wells, T, Welker, J, Foster, R, Gilmore, R, Anderson, J, Jacoby, D, Gardner, G, Dandillaya, R, Vora, K, Kostis, J, Hunter, J, Laxson, D, Ball, E, İÜC, and Ege Üniversitesi
- Subjects
Male ,medicine.medical_specialty ,Acute coronary syndrome ,alirocumab ,030204 cardiovascular system & hematology ,Antibodies, Monoclonal, Humanized ,lipids ,PCSK9 ,03 medical and health sciences ,0302 clinical medicine ,Postoperative Complications ,Double-Blind Method ,coronary artery bypass graft ,Internal medicine ,medicine ,Humans ,Cardiac and Cardiovascular Systems ,030212 general & internal medicine ,Myocardial infarction ,cardiovascular diseases ,Acute Coronary Syndrome ,Coronary Artery Bypass ,Alirocumab ,Aged ,Kardiologi ,business.industry ,Unstable angina ,Hazard ratio ,cholesterol ,Middle Aged ,medicine.disease ,surgical procedures, operative ,Bypass surgery ,Cardiovascular Diseases ,Cardiology ,Drug Therapy, Combination ,Female ,Hydroxymethylglutaryl-CoA Reductase Inhibitors ,Cardiology and Cardiovascular Medicine ,business ,Mace - Abstract
Sherwood, Matthew/0000-0002-4305-5883; Taskinen, Marja-Riitta/0000-0002-6229-3588; Leonardi, Sergio/0000-0002-4800-6132; Raffel, Owen C/0000-0001-5470-7050; Muenzel, Thomas/0000-0001-5503-4150; Ersanli, Murat/0000-0003-1847-3087; Gislason, Gunnar H/0000-0002-0548-402X; bastos, jose/0000-0002-9526-3123; Abbate, Antonio/0000-0002-1930-785X; Chumakova, Galina A/0000-0002-2810-6531; Nikolaev, Konstantin/0000-0003-4601-6203; Tse, Hung Fat/0000-0002-9578-7808; Keskin, Kudret/0000-0002-9049-1530; Reshetko, Olga/0000-0003-3107-7636; Podoleanu, Cristian/0000-0001-9987-2519; Aylward, Philip/0000-0002-5358-8552; LETIERCE, Alexia/0000-0001-6679-5772, WOS: 000483334800002, PubMed: 31466614, BACKGROUND Patients with acute coronary syndrome (ACS) and history of coronary artery bypass grafting (CABG) are at high risk for recurrent cardiovascular events and death. OBJECTIVES This study sought to determine the clinical benefit of adding alirocumab to statins in ACS patients with prior CABG in a pre-specified analysis of ODYSSEY OUTCOMES (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab). METHODS Patients (n = 18,924) 1 to 12 months post-ACS with elevated atherogenic lipoprotein levels despite high-intensity statin therapy were randomized to alirocumab or placebo subcutaneously every 2 weeks. Median follow-up was 2.8 years. the primary composite endpoint of major adverse cardiovascular events (MACE) comprised coronary heart disease death, nonfatal myocardial infarction, ischemic stroke, or unstable angina requiring hospitalization. All-cause death was a secondary endpoint. Patients were categorized by CABG status: no CABG (n = 16,896); index CABG after qualifying ACS, but before randomization (n = 1,025); or CABG before the qualifying ACS (n = 1,003). RESULTS in each CABG category, hazard ratios (95% confidence intervals) for MACE (no CABG 0.86 [0.78 to 0.95], index CABG 0.85 [0.54 to 1.35], prior CABG 0.77 [0.61 to 0.98]) and death (0.88 [ 0.75 to 1.03], 0.85 [0.46 to 1.59], 0.67 [0.44 to 1.01], respectively) were consistent with the overall trial results (0.85 [ 0.78 to 0.93] and 0.85 [0.73 to 0.98], respectively). Absolute risk reductions (95% confidence intervals) differed across CABG categories for MACE (no CABG 1.3% [0.5% to 2.2%], index CABG 0.9% [-2.3% to 4.0%], prior CABG 6.4% [0.9% to 12.0%]) and for death (0.4% [-0.1% to 1.0%], 0.5% [-1.9% to 2.9%], and 3.6% [0.0% to 7.2%]). CONCLUSIONS Among patients with recent ACS and elevated atherogenic lipoproteins despite intensive statin therapy, alirocumab was associated with large absolute reductions in MACE and death in those with CABG preceding the ACS event. (ODYSSEY OUTCOMES: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab; NCT01663402) (C) 2019 by the American College of Cardiology Foundation., Fondation Assistance Publique-Hopitaux de Paris, Paris, France, The authors thank the patients, study coordinators, and investigators who participated in this trial. Sophie Rushton-Smith, PhD (MedLink Healthcare Communications, London) provided editorial assistance in the preparation of the manuscript (limited to editing for style, referencing, and figure and table editing) and was funded by Fondation Assistance Publique-Hopitaux de Paris, Paris, France.
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- 2019
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198. Effect of Alirocumab on Mortality After Acute Coronary Syndromes An Analysis of the ODYSSEY OUTCOMES Randomized Clinical Trial
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Soonfuang, W, Jintapakorn, W, Sukonthasarn, A, Wongpraparut, N, Sastravaha, K, Sansanayudh, N, Kehasukcharoen, W, Piyayotai, D, Chotnoparatpat, P, Camsari, A, Kultursay, H, Mutlu, B, Ersanli, M, Demirtas, M, Kirma, C, Ural, E, Koldas, L, Karpenko, O, Prokhorov, A, Vakaluyk, I, Myshanych, H, Reshotko, D, Batushkin, V, Rudenko, L, Kovalskyi, I, Kushnir, M, Tseluyko, V, Mostovoy, Y, Stanislavchuk, M, Kyiak, Y, Karpenko, Y, Malynovsky, Y, Klantsa, A, Kutniy, O, Amosova, E, Tashchuk, V, Leshchuk, O, Rishko, M, Kopytsya, M, Yagensky, A, Vatutin, M, Bagriy, A, Barna, OM, Ushakov, O, Dzyak, G, Goloborodko, B, Rudenko, A, Zheleznyy, V, Trevelyan, J, Zaman, A, Lee, K, Moriarty, A, Aggarwal, RK, Clifford, P, Wong, Y-K, Iqbal, SMR, Subkovas, E, Braganza, D, Sarkar, D, Storey, R, Griffiths, H, Mcclure, S, Muthusamy, R, Kurian, J, Levy, T, Barr, C, Kadr, H, Gerber, R, Simaitis, A, Soran, H, Mathur, A, Brodison, A, Oliver, R, Mudawi, T, Reynolds, T, Sharman, D, Butler, R, Wilkinson, P, Lip, GYH, Halcox, J, Vardi, G, Baldari, D, Brabham, D, Treasure, C, Dahl, C, Palmer, B, Wiseman, A, Puri, S, Mohart, AE, Ince, C, Flores, E, Wright, S, Cheng, S-C, Rosenberg, M, Rogers, W, Kosinski, E, Forgosh, L, Waltman, J, Khan, M, Shoukfeh, M, Dagher, G, Lieber, I, Kumar, P, East, C, Krichmar, P, White, L, Knickelbine, T, Haldis, T, Gillespie, E, Suh, D, Arif, I, Akhter, F, Carlson, E, D'Urso, M, El-Ahdab, F, Nelson, W, Harris, B, Cohen, S, Carter, L, Sabatino, K, Haddad, T, Malik, A, Rao, S, Mulkay, A, Jovin, I, Klancke, K, Malhotra, V, Devarapalli, SK, Koren, M, Chandna, H, Dodds, G, Janik, M, Moran, J, Sumner, A, Kobayashi, J, Davis, W, Yazdani, S, Pasquini, J, Thakkar, M, Vedere, A, Leimbach, W, Rider, J, Singh, N, Shah, AV, Janosik, D, Pepine, C, Berman, B, Gelormini, J, Daniels, C, Keating, F, Kondo, NI, Shetty, S, Waider, W, Takata, T, Abu-Fadel, M, Shah, V, Aggarwal, R, Izzo, M, Kumar, A, Hattler, B, Link, C, Bortnick, A, Kinzfogl, G, Ghitis, A, Larry, J, Teufel, E, Kuhlman, P, Mclaurin, B, Zhang, W, Thew, S, Abbas, J, White, M, Ranadive, N, Gring, C, Henderson, D, Schuchard, T, Farhat, N, Kline, G, Mahal, S, Whitaker, J, Speirs, S, Andersen, R, Daboul, N, Horwitz, P, Ponce, G, Jafar, Z, Mcgarvey, J, Panchal, V, Voyce, S, Blok, T, Sheldon, W, Azizad, MM, Schmalfuss, C, Picone, M, Herzog, W, Lindsey, J, Nowins, R, Lepor, N, El Shahawy, M, Weintraub, H, Irimpen, A, May, W, Galski, T, Chu, A, Mody, F, Hodes, Z, Rose, G, Fairlamb, J, Lambert, C, Raisinghani, A, Abbate, A, King, M, Carey, C, Gerber, J, Younis, L, Park, HT, Vidovich, M, Knutson, T, Friedman, D, Chaleff, F, Loussararian, A, Rozeman, P, Kimmelstiel, C, Silver, K, Foster, M, Tonnessen, G, Amlani, M, Wali, A, Malozzi, C, Wattanakit, K, O'Donnell, PJ, Singal, D, Jaffrani, N, Banuru, S, Fisher, D, Xenakis, M, Perlmutter, N, Bhagwat, R, Strader, J, Akyea-Djamson, A, Labroo, A, Marais, HJ, Claxton, E, Berk, M, Rossi, P, Joshi, P, Khaira, AS, Kumkumian, G, Lupovitch, S, Purow, J, Welka, S, Hoffman, D, Fischer, S, Soroka, E, Eagerton, D, Pancholy, S, Ray, M, Farrar, M, Pollock, S, French, WJ, Diamantis, S, Gimple, L, Neustel, M, Schwartz, S, Pereira, E, Spriggs, D, Strain, J, Vo, A, Chane, M, Hall, J, Vijay, N, Lotun, K, Lester, FM, Nahhas, A, Pope, T, Nager, P, Vohra, R, Bashir, R, Ahmed, H, Berlowitz, M, Fishberg, R, Barrucco, R, Yang, E, Radin, M, Sporn, D, Eisenberg, S, Landzberg, J, Mcgough, M, Turk, S, Schwartz, M, Sundram, PS, Jain, D, Zainea, M, Bayron, C, Karlsberg, R, Lui, H, Keen, W, Westerhausen, D, Khurana, S, Agarwal, H, Birchem, J, Penny, W, Chang, M, Murphy, S, Schifferdecker, B, Gilbert, JM, Chalavarya, G, Eaton, C, Schmedtje, JF, Christenson, S, Denham, D, Macdonell, A, Gibson, P, Rahman, A, Al Joundi, T, Conrad, G, Kotha, P, Love, M, Giesler, G, Rubenstein, H, Akright, L, Krawczyk, J, Wells, T, Welker, J, Foster, R, Gilmore, R, Anderson, J, Jacoby, D, Gardner, G, Dandillaya, R, Vora, K, Kostis, J, Hunter, J, Laxson, D, Ball, E, Camp, A, Lopes, R, Egydio, F, Kawakami, A, Oliveira, J, Wozniak, J, Matthews, A, Ratky, C, Valiris, J, Berdan, L, Hepditch, A, Quintero, K, Rorick, T, Westbrook, M, Pascual, A, Rovito, C, Bezault, M, Drouet, E, Simon, T, Alsweiler, C, Luyten, A, Aylward, P, Butters, J, Griffith, L, Shaw, M, Grunberg, L, Islam, S, Bougon, N, Faustino, D, Fontecave, S, Murphy, J, Verrier, M, Agnetti, V, Andersen, D, Badreddine, E, Bekkouche, M, Bouancheau, C, Brigui, I, Brocklehurst, M, Cianciarulo, J, Devaul, D, Domokos, S, Gache, C, Gobillot, C, Guillou, S, Healy, J, Heath, M, Jaiwal, G, Javierre, C, Labeirie, J, Monier, M, Morales, U, Mrabti, A, Mthombeni, B, Okan, B, Smith, L, Sheller, J, Sopena, S, Pellan, V, Benbernou, F, Bengrait, N, Lamoureux, M, Kralova, K, Scemama, M, Bejuit, R, Coulange, A, Berthou, C, Repincay, J, Lorenzato, C, Etienne, A, Gouet, V, Loizeau, V, Normand, M, Ourliac, A, Rondel, C, Adamo, A, Beltran, P, Barraud, P, Dubois-Gache, H, Halle, B, Metwally, L, Mourgues, M, Sotty, M, Vincendet, M, Cotruta, R, Zhu, C, Fournie-Lloret, D, Morrello, C, Perthuis, A, Picault, P, Zobouyan, I, ODYSSEY OUTCOMES Comm, İÜC, Ege Üniversitesi, Rushton-Smith, Sophie, and ODYSSEY OUTCOMES Committees and Investigators
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Male ,Cardiac & Cardiovascular Systems ,MONOCLONAL-ANTIBODY ,alirocumab ,Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage ,law.invention ,PCSK9 ,chemistry.chemical_compound ,Randomized controlled trial ,law ,Cardiac and Cardiovascular Systems ,1102 Cardiorespiratory Medicine and Haematology ,Hypercholesterolemia/blood ,Kardiologi ,Hazard ratio ,Middle Aged ,Treatment Outcome ,SAFETY ,Cardiology ,Female ,Drug Therapy, Combination ,Cholesterol, LDL/antagonists & inhibitors ,Cardiology and Cardiovascular Medicine ,Life Sciences & Biomedicine ,REDUCING LIPIDS ,Akutes Koronarsyndrom ,acute coronary syndrome ,cholesterol ,mortality ,PCSK9 protein ,Antibodies, Monoclonal, Humanized/administration & dosage ,medicine.medical_specialty ,Acute coronary syndrome ,Injections, Subcutaneous ,Hypercholesterolemia ,Placebo ,Antibodies, Monoclonal, Humanized ,1117 Public Health and Health Services ,Sterblichkeit ,Double-Blind Method ,Physiology (medical) ,Internal medicine ,medicine ,Humans ,ddc:610 ,Alirocumab ,Aged ,Science & Technology ,Cholesterol ,business.industry ,EVOLOCUMAB ,1103 Clinical Sciences ,Cholesterol, LDL ,medicine.disease ,EFFICACY ,Increased risk ,chemistry ,Peripheral Vascular Disease ,Cardiovascular System & Hematology ,Cardiovascular System & Cardiology ,Acute Coronary Syndrome/blood ,Cholesterin ,Human medicine ,Hydroxymethylglutaryl-CoA Reductase Inhibitors ,business ,Follow-Up Studies - Abstract
bastos, jose/0000-0002-9526-3123; Manakshe, Gajendra/0000-0002-4983-4271; Tse, Hung Fat/0000-0002-9578-7808; Gislason, Gunnar H/0000-0002-0548-402X; Taskinen, Marja-Riitta/0000-0002-6229-3588; Racca, Vittorio/0000-0002-4465-3789; Keskin, Kudret/0000-0002-9049-1530; Sherwood, Matthew/0000-0002-4305-5883; Sandhu, Manjinder/0000-0003-2538-2079; Nikolaev, Konstantin/0000-0003-4601-6203; Ersanli, Murat/0000-0003-1847-3087; Raffel, Owen C/0000-0001-5470-7050; Abbate, Antonio/0000-0002-1930-785X; Muenzel, Thomas/0000-0001-5503-4150; Leonardi, Sergio/0000-0002-4800-6132; Chumakova, Galina A/0000-0002-2810-6531; Podoleanu, Cristian/0000-0001-9987-2519; Pereira, Helder/0000-0001-8656-4883; Reshetko, Olga/0000-0003-3107-7636, WOS: 000476768100007, PubMed: 31117810, Background: Previous trials of PCSK9 (proprotein convertase subtilisin-kexin type 9) inhibitors demonstrated reductions in major adverse cardiovascular events, but not death. We assessed the effects of alirocumab on death after index acute coronary syndrome. Methods: ODYSSEY OUTCOMES (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab) was a double-blind, randomized comparison of alirocumab or placebo in 18 924 patients who had an ACS 1 to 12 months previously and elevated atherogenic lipoproteins despite intensive statin therapy. Alirocumab dose was blindly titrated to target achieved low-density lipoprotein cholesterol (LDL-C) between 25 and 50 mg/dL. We examined the effects of treatment on all-cause death and its components, cardiovascular and noncardiovascular death, with log-rank testing. Joint semiparametric models tested associations between nonfatal cardiovascular events and cardiovascular or noncardiovascular death. Results: Median follow-up was 2.8 years. Death occurred in 334 (3.5%) and 392 (4.1%) patients, respectively, in the alirocumab and placebo groups (hazard ratio [HR], 0.85; 95% CI, 0.73 to 0.98; P=0.03, nominal P value). This resulted from nonsignificantly fewer cardiovascular (240 [2.5%] vs 271 [2.9%]; HR, 0.88; 95% CI, 0.74 to 1.05; P=0.15) and noncardiovascular (94 [1.0%] vs 121 [1.3%]; HR, 0.77; 95% CI, 0.59 to 1.01; P=0.06) deaths with alirocumab. in a prespecified analysis of 8242 patients eligible for >= 3 years follow-up, alirocumab reduced death (HR, 0.78; 95% CI, 0.65 to 0.94; P=0.01). Patients with nonfatal cardiovascular events were at increased risk for cardiovascular and noncardiovascular deaths (P= 100 mg/dL (2.59 mmol/L) had a greater absolute risk of death and a larger mortality benefit from alirocumab (HR, 0.71; 95% CI, 0.56 to 0.90; P-interaction=0.007). in the alirocumab group, all-cause death declined with achieved LDL-C at 4 months of treatment, to a level of approximately 30 mg/dL (adjusted P=0.017 for linear trend). Conclusions: Alirocumab added to intensive statin therapy has the potential to reduce death after acute coronary syndrome, particularly if treatment is maintained for >= 3 years, if baseline LDL-C is >= 100 mg/dL, or if achieved LDL-C is low., Sanofi; Regeneron Pharmaceuticals, Inc., The trial was funded by Sanofi and Regeneron Pharmaceuticals, Inc.
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199. Course 'Logorhythmics' as a means of verbal development of children of early and young preschool age in down
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Privalova, S. E. and Baranova, E. A.
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ОБРАЗОВАНИЕ. ПЕДАГОГИКА ,CHILDREN'S SPEECH ,LOGORHYTHMICS ,РЕЧЕВОЕ РАЗВИТИЕ ,ИГРОВАЯ ДЕЯТЕЛЬНОСТЬ ,РАННИЙ ВОЗРАСТ ,ДОШКОЛЬНЫЕ ОБРАЗОВАТЕЛЬНЫЕ УЧРЕЖДЕНИЯ ,ДОШКОЛЬНАЯ ПЕДАГОГИКА ,EARLY AGE ,МЛАДШИЕ ДОШКОЛЬНИКИ ,SPEECH ACTIVITY ,PRESCHOOL EDUCATIONAL INSTITUTIONS ,РАЗВИТИЕ РЕЧИ ,YOUNGER PRESCHOOLERS ,ЛОГОРИТМИКА ,РЕЧЕВЫЕ НАВЫКИ ,РЕЧЕВАЯ ДЕЯТЕЛЬНОСТЬ ,ДЕТСКАЯ РЕЧЬ ,SPEECH DEVELOPMENT - Abstract
В статье рассматриваются возможности курса "Логоритмика" для решения задач речевого развития у детей раннего и младшего дошкольного возраста в ДОУ. Раскрыты возрастные особенности развития речи детей данного возраста. Перечислены некоторые компоненты речевой активности детей младшего дошкольного возраста: поведенческий, мотивационный, оперативный. На основе исследований В. С. Вавиловой, Т. Г. Хановой подчеркивается, что речевая активность детей дошкольного возраста является условием усвоения речевой деятельности, речевого общения, показателем развития интеллекта, которое проявляется в стремлении к речевой деятельности. На основе пособия В. И. Селиверстова приведены некоторые примеры игровых упражнений, которые способствуют воспитанию отчетливого и правильного звукопроизношения, улучшает слуховую и зрительную память; позволяют решать задачи по овладению синтаксической и морфологической стороной речи у детей раннего и младшего дошкольного возраста. The article discusses the possibilities of the course "Logorhythmics" for solving the problems of speech development in children of early and younger preschool age at preschool education. Disclosed age features of speech development of children of this age. Some components of speech activity of children of younger preschool age are listed: behavioral, motivational, operational. Based on research V. S. Vavilova, T. G. Khanova emphasizes that speech activity of preschool children is a condition for the assimilation of speech activity, speech communication, an indicator of the development of intelligence, which is manifested in the desire for speech activity. Based on the manual V. I. Seliverstova gives some examples of playing exercises that contribute to the development of a distinct and correct sound pronunciation, improves the auditory and visual memory; allow you to solve problems in mastering the syntactic and morphological side of speech in children of early and younger preschool age.
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200. Electrochemical promotion of propylene combustion on Ag catalytic coatings
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Kalaitzidou, I., Cavoue, T., Boreave, A., Burel, L., Gaillard, F., Retailleau-Mevel, L., Baranova, E., Rieu, M., Viricelle, J. P., David Horwat, Caravaca, A., Vernoux, P., IRCELYON, ProductionsScientifiques, IRCELYON-Catalytic and Atmospheric Reactivity for the Environment (CARE), Institut de recherches sur la catalyse et l'environnement de Lyon (IRCELYON), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), and IRCELYON-Microscopie (MICROSCOPIE)
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[CHIM.CATA] Chemical Sciences/Catalysis ,[CHIM.CATA]Chemical Sciences/Catalysis ,[SDE.ES] Environmental Sciences/Environmental and Society ,[SDE.ES]Environmental Sciences/Environmental and Society - Abstract
MICROSCOPIE+CARE+IKL:TCV:ABO:LBU:FGA:LRE:ACV:PVE; International audience; Catalytic combustion as a process used for removal of hydrocarbons from automotive gas exhausts or for energy production has been widely implemented on supported PGM (Platinum Group Metals) based catalysts1. Since PGMs are very costly and rare, there is a strong need for an equally effective and less expensive catalyst. The electrochemical promotion of catalysis (EPOC), is a promising concept to in-operando boost catalytic processes in a reversible and controlled manner2. The aim of this study was to develop Ag-based electrochemical catalysts for low temperature propylene deep oxidation. EPOC of propylene combustion has been carried out in the literature but mainly on Pt catalytic films1,3, while this phenomenon was attributed to the modification in the propylene chemisorption3.Nanostructured electrochemical catalysts were prepared by screen-printing and reactive Physical Vapor Deposition (PVD) method. Thickness and porosity of Ag coatings were modified by changing the deposition parameters (duration and pressure for PVD, nature of the ink and calcination temperature for screen-printing) to optimize the catalytic properties. Catalytic and electrocatalytic tests have been carried out in a quartz reactor1 which operated under continuous flowing conditions at atmospheric pressure. The catalytic activity was monitored in a temperature range of 100 to 400oC under lean-burn conditions, as encountered in Diesel exhausts. The most active Ag films were also evaluated under closed circuit conditions (± 2V) in order to measure the effect of polarization between the Ag working electrode and an Au reference electrode. Both electrodes were exposed to the same atmosphere in a single chamber configuration.Values of Faradaic efficiencies in the range of 300 were obtained while the conversion could be tailored from 14 to 21% (Fig. 1). Negative current applications lead to the decrease of the CO2 production while positive current application corresponds to a pronounced increase of the catalytic performance. Upon positive current applications, the rate enhancement ratio increases with the intensity of the current. This indicates that the coverage of promoting ionic species (Oδ-) increases with the current, then producing more weakly bonded oxygen species coming from the gas phase4.This study reports, for the first time, that the catalytic activity for propylene of Ag coatings deposited onto YSZ can be tailored by current applications in a non-Faradaic manner. The predominant impact of current applications is to modify the reactivity of oxygen present on the Ag surface. Positive current applications increase the propylene conversion by producing more reactive oxygen species. This beneficial effect is more pronounced in an oxidizing atmosphere, where the oxygen coverage on Ag is high. This demonstrates that EPOC can enhance catalytic properties of Ag coatings for the abatement of propylene in air.References 1.P. Vernoux et al., J. Catal., 208 (2002) 412-421.2.C.G. Vayenas, Electrochemical Activation of Catalysis: Promotion, Electrochemical Promotion, and Metal-Support Interactions, Springer, 2001.3.A. Kaloyannis et al., J. Catal., 182 (1999) 37-47.4.I. Kalaitzidou et al., Materials Today: Proceedings, 5, 27345 (2018).Acknowledgments: This study was performed in the “EPOX” project, funded by the French National Research Agency (ANR), ANR-2015-CE07-0026.
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Catalog
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