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160. Contributors

Author

Anderson, Jamie G., primary, Arzi, Boaz, additional, Bardach (deceased), Janusz, additional, Bezuidenhout, Abraham J., additional, Bonello, Dea, additional, Boudrieau, Randy J., additional, Chamberlain, Thomas P., additional, Eisner, Edward R., additional, Fitch, Patricia Frost, additional, Gorrel, Cecilia E., additional, Gracis, Margherita, additional, Gregory, Clare R., additional, Hale, Fraser A., additional, Härle, Franz, additional, Holmstrom, Steven E., additional, Kelly, Kevin M., additional, Köstlin, Roberto, additional, Lane, J. Geoffrey, additional, Lantz, Gary C., additional, Le, Anh D., additional, Legendre, Loïc F.J., additional, Lommer, Milinda J., additional, Marretta, Sandra Manfra, additional, Marks, Stanley L., additional, Mathews, Kyle G., additional, Matis, Ulrike, additional, McEntee, Margaret C., additional, Pascoe, Peter J., additional, Peavy, George M., additional, Peeters, Marijke E., additional, Pogrel, M. Anthony, additional, Regezi, Joseph A., additional, Roy, Celeste G., additional, M. Sarkiala-Kessel, Eva, additional, Séguin, Bernard, additional, Shetty, Vivek, additional, Smeak, Daniel D., additional, Smith, Mark M., additional, Staley, Barry B., additional, Swaim, Steven F., additional, Terpak, Cheryl H., additional, Tsugawa, Anson J., additional, Verstraete, Frank J.M., additional, Walsh, Peter J., additional, Wang, Xudong, additional, Wiggs (deceased), Robert W., additional, and Wilder-Smith, Petra E., additional

Published
2012
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162. List of Contributors

Author

Acke, Els, Adolph, Christopher B., Afonso, Maria, Allen, Kelly E., Arzi, Boaz, Balsa, Ingrid, Baneth, Gad, Barber, Renee, Barker, Emi N., Barrs, Vanessa R., Beatty, Julia A., Berg, Mikael, Birkenheuer, Adam J., Blagburn, Byron L., Bond, Ross, Bowman, Dwight D., Breitschwerdt, Edward B., Buonavoglia, Canio, Burgess, Brandy A., Burkitt Creedon, Jamie M., Byrne, Barbara A., Casal, Margret L., Chalker, Victoria J., Chomel, Bruno B., Cohn, Leah A., Cole, Lynette K., Cole, Stephen D., Conboy, Gary A., Cortinas, Roberto, Coyner, Kimberly, Culp, William T.N., Daniels, Joshua B., Davidson, Autumn P., Dear, Jonathan D., Decaro, Nicola, DeClue, Amy E., Diaz-Campos, Dubraska, Diniz, Pedro Paulo V.P., Dubey, Jitender P., Dubovi, Edward J., Eckstrand, Chrissy, Ellis, John A., Elsemore, David A., Epstein, Steven E., Evermann, James F., Foley, Janet E., Giger, Urs, Goldstein, Ellie J.C., Granick, Jennifer, Gremião, Isabella D.F., Grooters, Amy M., Gunn-Moore, Danièlle A., Guptill, Lynn, Hamer, Sarah A., Harrus, Shimon, Hartmann, Katrin, Henke, Diana, Hodzic, Emir, Hofmann-Lehmann, Regina, Howerth, Elizabeth W., Jäderlund, Karin Hultin, Hurley, Kate F., Jacobson, Linda S., Wensman, Jonas Johansson, Kapatkin, Amy S., Kent, Marc, Ketzis, Jennifer K., Kidd, Linda, Kraus, Stacy, Krockenberger, Mark, Lappin, Michael R., Lee, Alice C.Y., Lee-Fowler, Tekla, Little, Susan E., Littman, Meryl P., Lobetti, Remo, Lucio-Forster, Araceli, Luff, Jennifer A., Lutz, Hans, Marcondes, Mary, Marks, Stanley L., Marsilio, Sina, McDonough, Patrick L., Menezes, Rodrigo C., Merkel, Lindsay, Mills, W. Zach, Miranda, Luisa H.M., Moore, George E., Moriello, Karen A., Mourning, Alyssa C., Munday, John S., Mylonakis, Mathios E., Nagamori, Yoko, Nelson, C. Thomas, Nordstoga, Anne B., Norris, Jacqueline M., O’Brien, Carolyn R., O’Halloran, Conor, Otto, Cynthia M., Papich, Mark G., Parrish, Colin R., Pedersen, Niels C., Peregrine, Andrew S., Pereira, Sandro A., Petersen, Christine, Prescott, John F., Priestnall, Simon L., Qurollo, Barbara, Radford, Alan, Rankin, Shelley C., Reagan, Krystle L., Reichard, Mason V., Reinero, Carol, Saleh, Meriam N., Sapp, Sarah G.H., Saunders, Ashley B., Schubach, Tânia M.P., Schuller, Simone, Scorza, Valeria, Sellon, Rance K., Sharp, Claire R., Silverstein, Deborah, Singh, Ameet, Sinnott-Stutzman, Virginia, Snowden, Karen F., Solano-Gallego, Laia, Spindel, Miranda, Starkey, Lindsay A., Stern, Joshua A., Stiles, Jean, Straubinger, Reinhard K., Stull, Jason W., Sykes, Jane E., Tasker, Séverine, Thomas, Jennifer E., Thomasy, Sara M., Tipold, Andrea, Tolbert, M. Katherine, Vahlenkamp, Thomas W., Vandevelde, Marc, Vincent-Johnson, Nancy, Vishkautsan, Polina, Waner, Trevor, Weese, J. Scott, Westropp, Jodi L., White, Stephen D., Winston, Jenessa A., Wulcan, Judit M., and Yabsley, Michael J.

Published
2023
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163. Radiographic outcome of root canal treatment in dogs: 281 teeth in 204 dogs (2001-2018).

Author

Da Bin Lee, Arzi, Boaz, Kass, Philip H., and Verstraete, Frank J. M.

Subjects
*ROOT canal treatment, *MEDICAL record databases, *ROOT resorption (Teeth), *TEETH, *DOGS, *PERIODONTAL ligament
Abstract

OBJECTIVE To evaluate the radiographic outcome of root canal treatment (RCT) in dogs and compare outcomes with those reported for a previous study performed at the same institution in 2002. ANIMALS 204 dogs representing 281 teeth that underwent RCT. PROCEDURES The medical record database of a veterinary teaching hospital was searched to identify dogs that underwent RCT between 2001 and 2018. Only dogs that had undergone at least 1 radiographic recheck appointment a minimum of 50 days after RCT were included in the study. Dental radiographs were reviewed. Treatment was considered successful if the periapical periodontal ligament space was within reference limits and preexisting external inflammatory root resorption (EIRR), if present, had stabilized. Treatment was considered to show no evidence of failure (NEF) if preoperative EIRR had stabilized and any preoperative periapical lucency (PAL) remained the same or had decreased in size but had not completely resolved. Treatment was considered to have failed if EIRR or a PAL developed after RCT, if a preoperative PAL increased in size, or if preexisting EIRR progressed. RESULTS Follow-up time ranged from 52 to 3,245 days (mean, 437 days). RCT was classified as successful for 199 (71%) teeth, NEF for 71 (25%) teeth, and failed for 11 (4%) teeth. CONCLUSIONSANDCLINICALRELEVANCE Results showed that almost 2 decades after RCT outcome in dogs was first evaluated, durjng which time numerous advances in dental materials and techniques had been made, the success rate of RCT was virtually unchanged. [ABSTRACT FROM AUTHOR]

Published
2022
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164. Multipotent Stromal Cells and Viral Interaction: Current Implications for Therapy.

Author

Taechangam, Nopmanee, Kol, Amir, Arzi, Boaz, and Borjesson, Dori L.

Subjects
STROMAL cells, VIRUS diseases, MESENCHYMAL stem cells, COMMUNICABLE diseases, IMMUNE response, VIRAL replication
Abstract

Multipotent stromal cells (MSCs) are widely utilized in therapy for their immunomodulatory properties, but their usage in infectious viral diseases is less explored. This review aimed to collate the current novel use of MSCs in virus-associated conditions, including MSC's susceptibility to virus infection, antiviral properties of MSCs and their effects on cell-based immune response and implementation of MSC therapy in animal models and human clinical trials of viral diseases. Recent discoveries shed lights on MSC's capability in suppressing viral replication and augmenting clearance through enhancement of antiviral immunity. MSC therapy may maintain a crucial balance between aiding pathogen clearance and suppressing hyperactive immune response. [ABSTRACT FROM AUTHOR]

Published
2022
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172. A multicenter experience using adipose-derived mesenchymal stem cell therapy for cats with chronic, non-responsive gingivostomatitis

Author

Arzi, Boaz, primary, Peralta, Santiago, additional, Fiani, Nadine, additional, Vapniarsky, Natalia, additional, Taechangam, Nopmanee, additional, Delatorre, Ubaldo, additional, Clark, Kaitlin C., additional, Walker, Naomi J., additional, Loscar, Megan R., additional, Lommer, Milinda J., additional, Fulton, Amy, additional, Battig, Jean, additional, and Borjesson, Dori L., additional

Published
2020
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175. Additional file 1: of Mechanisms utilized by feline adipose-derived mesenchymal stem cells to inhibit T lymphocyte proliferation

Author

Nopmanee Taechangam, Iyer, Smita, Walker, Naomi, Arzi, Boaz, and Borjesson, Dori

Subjects
hemic and immune systems
Abstract

Figure S1. Feline ASCs do not downregulate PD-1 expression on activated PBMCs. Flow analysis on PD-1 expression on activated T lymphocytes with and without co-incubation with feline ASCs. Representative image of flow cytometry analysis from 3 different MSC lines. (DOCX 185 kb)

Published
2019
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176. Kinematic analysis of mandibular motion before and after mandibulectomy and mandibular reconstruction in dogs.

Author

Arzi, Boaz and Arzi, Boaz

Abstract

OBJECTIVE:To evaluate and quantify the kinematic behavior of canine mandibles before and after bilateral rostral or unilateral segmental mandibulectomy as well as after mandibular reconstruction with a locking reconstruction plate in ex vivo conditions. SAMPLE:Head specimens from cadavers of 16 dogs (range in body weight, 30 to 35 kg). PROCEDURE:Specimens were assigned to undergo unilateral segmental (n = 8) or bilateral rostral (8) mandibulectomy and then mandibular reconstruction by internal fixation with locking plates. Kinematic markers were attached to each specimen in a custom-built load frame. Markers were tracked in 3-D space during standardized loading conditions, and mandibular motions were quantified. Differences in mandibular range of motion among 3 experimental conditions (before mandibulectomy [ie, with mandibles intact], after mandibulectomy, and after reconstruction) were assessed by means of repeated-measures ANOVA. RESULTS:Both unilateral segmental and bilateral rostral mandibulectomy resulted in significantly greater mandibular motion and instability, compared with results for intact mandibles. No significant differences in motion were detected between mandibles reconstructed after unilateral segmental mandibulectomy and intact mandibles. Similarly, the motion of mandibles reconstructed after rostral mandibulectomy was no different from that of intact mandibles, except in the lateral direction. CONCLUSIONS AND CLINICAL RELEVANCE:Mandibular kinematics in head specimens from canine cadavers were significantly altered after unilateral segmental and bilateral rostral mandibulectomy. These alterations were corrected after mandibular reconstruction with locking reconstruction plates. Findings reinforced the clinical observations of the beneficial effect of reconstruction on mandibular function and the need for reconstructive surgery after mandibulectomy in dogs.

Published
2019

177. Stem cell therapy prior to full-mouth tooth extraction lacks substantial clinical efficacy in cats affected by chronic gingivostomatitis.

Author

Arzi, Boaz, Taechangam, Nopmanee, Lommer, Milinda J, Walker, Naomi J, Loscar, Megan R, and Borjesson, Dori L

Abstract

Objectives: The aim of this pilot study was to determine the safety, efficacy and immunomodulatory function of systemically administered adipose-derived mesenchymal stem cells (ASCs) in cats affected by feline chronic gingivostomatitis (FCGS) prior to full-mouth tooth extractions. Methods: Five client-owned cats affected with FCGS that did not undergo full-mouth tooth extractions for FCGS treatment received two intravenous injections of 20 million fresh, allogeneic or autologous ASCs. An oral examination with photographs, a complete blood count, blood immune cell phenotyping and a biochemical profile were completed at 0 and 6 months after treatment. Results: Four cats completed the study and one cat exited the study 3 months after treatment. While the treatment was determined to be clinically safe, no positive clinical response was observed in three cats and a mild response was noted in two cats. Furthermore, none of the cats exhibited immune modulation, as evidenced by no alteration in circulating CD8+ T cells, normalization of the CD4:CD8 ratio or neutrophil counts. Conclusions and relevance: Unlike the reported efficacy of ASCs in treating cats with non-responsive FCGS after full-mouth tooth extraction, the systemic administration of ASCs prior to full-mouth tooth extraction lacks substantial clinical efficacy and is not recommended at this time. [ABSTRACT FROM AUTHOR]

Published
2021
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196. The case against the use of dental implants in dogs and cats

Author

Tannenbaum, Jerrold, primary, Arzi, Boaz, additional, Reiter, Alexander M., additional, Peralta, Santiago, additional, Snyder, Christopher J., additional, Lommer, Milinda J., additional, Harvey, Colin E., additional, Soukup, Jason W., additional, and Verstraete, Frank J. M., additional

Published
2013
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