1,136 results on '"Ariza Solé A"'
Search Results
152. Economic evaluation of restrictive vs. liberal transfusion strategy following acute myocardial infarction (REALITY): trial-based cost–effectiveness and cost–utility analyses
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Durand-Zaleski, Isabelle, primary, Ducrocq, Gregory, additional, Mimouni, Maroua, additional, Frenkiel, Jerome, additional, Avendano-Solá, Cristina, additional, Gonzalez-Juanatey, Jose R, additional, Ferrari, Emile, additional, Lemesle, Gilles, additional, Puymirat, Etienne, additional, Berard, Laurence, additional, Cachanado, Marine, additional, Arnaiz, Joan Albert, additional, Martínez-Sellés, Manuel, additional, Silvain, Johanne, additional, Ariza-Solé, Albert, additional, Calvo, Gonzalo, additional, Danchin, Nicolas, additional, Paco, Sandra, additional, Drouet, Elodie, additional, Abergel, Helene, additional, Rousseau, Alexandra, additional, Simon, Tabassome, additional, and Steg, Philippe Gabriel, additional
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- 2022
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153. 105 - ESTUDIO PROSPECTIVO SOBRE EL PERFIL DE SEGURIDAD DE UN CURSO CONVENCIONAL DE CORTICOIDES SISTÉMICOS EN LA ENFERMEDAD INFLAMATORIA INTESTINAL
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Mercè Navarro-Llavat, Orlando García-Bosch, Jesús Castro-Poceiro, Ana Bargalló García, Dolores Ruiz Arroyo, Yolanda Navas Bravo, Eva Erice Muñoz, Claudia Berbel Comas, David Barquero Declara, Alfredo Mata Bilbao, Marta Martín Llahí, Xavier Ariza Solé, Alba Juan Juan, Carlos Hernández Ballesteros, Katherine Bustamante Robles, Alex Blasco Pelicano, Mercè Albareda Riera, and Eugeni Domènech Morral
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Hepatology ,Gastroenterology - Published
- 2023
154. 91 - ESTUDIO PROSPECTIVO SOBRE LA SATISFACCIÓN Y EL IMPACTO EN LA CALIDAD DE VIDA DEL TRATAMIENTO CON CORTICOIDES EN PACIENTES CON ENFERMEDAD INFLAMATORIA INTESTINAL
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Mercè Navarro-Llavat, Orlando García-Bosch, Jesús Castro-Poceiro, Ana Bargalló García, Dolores Ruiz Arroyo, Yolanda Navas Bravo, Eva Erice Muñoz, Claudia Berbel Comas, David Barquero Declara, Alfredo Mata Bilbao, Marta Martín LLahí, Xavier Ariza Solé, Alba Juan Juan, Carlos Hernández Ballesteros, Katherine Bustamante Robles, Alex Blasco Pelicano, Mercè Albareda Riera, and Eugeni Domènech Morral
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Hepatology ,Gastroenterology - Published
- 2023
155. Machine learning-based prediction of adverse events following an acute coronary syndrome (PRAISE): a modelling study of pooled datasets
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Iván J. Núñez-Gil, José Ramón González Juanatey, Marco G. Mennuni, Umberto Michelucci, Sergio Manzano-Fernández, Tim Kinnaird, Marco Aldinucci, Claudio Montalto, Giuseppe Patti, Pierluigi Omedè, Gianluca Mittone, Tetsuma Kawaji, Berenice Caneiro Queija, Lazar Velicki, Dario Piga, Alessandro Durante, Francesco Bruno, Stephen B. Wilton, Roberto Esposito, Andrés Íñiguez-Romo, Sergio Raposeiras-Roubín, Enrico Cerrato, Ovidio De Filippo, Iacopo Colonnelli, Masa-aki Kawashiri, Walter Grosso Marra, Andrea Saglietto, Guglielmo Gallone, Michela Sperti, Pier Paolo Bocchino, Gianluca Campo, Albert Ariza-Solé, Rafael Cobas-Paz, Angel Cequier, Antonio Montefusco, Federico Conrotto, Sergio Leonardi, Barbara Cantalupo, Andrea Rognoni, Alaide Chieffo, Marco Agostino Deriu, Francesco Piroli, Yasir Arfat, Fabrizio D'Ascenzo, Zenon Huczek, Alberto Dominguez-Rodriguez, Sebastiano Gili, Giorgio Quadri, Isabel Muñoz Pousa, María Cespón Fernández, Ferdinando Varbella, James M. Hughes, Mauro Pennone, Luigi Oltrona Visconti, José P.S. Henriques, Xiantao Song, Ioanna Xanthopoulou, Pedro Flores Blanco, Simone Biscaglia, Gaetano M. De Ferrari, Umberto Morbiducci, Giuseppe Biondi Zoccai, Shaoping Nie, Toshiharu Fujii, Emad Abu-Assi, Dimitrios Alexopoulos, Alberto Garay, Ángel López-Cuenca, Giacomo Boccuzzi, Christoph Liebetrau, Marta Malavolta, Mario Iannaccone, Cardiology, and ACS - Atherosclerosis & ischemic syndromes
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Adult ,Male ,Acute coronary syndrome ,media_common.quotation_subject ,Clinical Decision-Making ,MEDLINE ,Datasets as Topic ,Socio-culturale ,Hemorrhage ,030204 cardiovascular system & hematology ,Machine learning ,computer.software_genre ,law.invention ,Machine Learning ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Randomized controlled trial ,law ,Humans ,Medicine ,acute coronary syndromes ,030212 general & internal medicine ,Myocardial infarction ,Acute Coronary Syndrome ,Mortality ,Praise ,Adverse effect ,cardiovascular disease ,machine learning ,myocardial infarction ,media_common ,Receiver operating characteristic ,business.industry ,General Medicine ,medicine.disease ,3. Good health ,Cohort ,Female ,Artificial intelligence ,business ,computer - Abstract
Summary Background The accuracy of current prediction tools for ischaemic and bleeding events after an acute coronary syndrome (ACS) remains insufficient for individualised patient management strategies. We developed a machine learning-based risk stratification model to predict all-cause death, recurrent acute myocardial infarction, and major bleeding after ACS. Methods Different machine learning models for the prediction of 1-year post-discharge all-cause death, myocardial infarction, and major bleeding (defined as Bleeding Academic Research Consortium type 3 or 5) were trained on a cohort of 19 826 adult patients with ACS (split into a training cohort [80%] and internal validation cohort [20%]) from the BleeMACS and RENAMI registries, which included patients across several continents. 25 clinical features routinely assessed at discharge were used to inform the models. The best-performing model for each study outcome (the PRAISE score) was tested in an external validation cohort of 3444 patients with ACS pooled from a randomised controlled trial and three prospective registries. Model performance was assessed according to a range of learning metrics including area under the receiver operating characteristic curve (AUC). Findings The PRAISE score showed an AUC of 0·82 (95% CI 0·78–0·85) in the internal validation cohort and 0·92 (0·90–0·93) in the external validation cohort for 1-year all-cause death; an AUC of 0·74 (0·70–0·78) in the internal validation cohort and 0·81 (0·76–0·85) in the external validation cohort for 1-year myocardial infarction; and an AUC of 0·70 (0·66–0·75) in the internal validation cohort and 0·86 (0·82–0·89) in the external validation cohort for 1-year major bleeding. Interpretation A machine learning-based approach for the identification of predictors of events after an ACS is feasible and effective. The PRAISE score showed accurate discriminative capabilities for the prediction of all-cause death, myocardial infarction, and major bleeding, and might be useful to guide clinical decision making. Funding None.
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- 2021
156. Frailty Tools for Assessment of Long-term Prognosis After Acute Coronary Syndrome
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Clara Sastre, Jessika González, Juan Sanchis, Vicente Pernias, Gema Miñana, Ernesto Valero, Anna Mollar, Vicent Ruiz, Julio Núñez, Clara Bonanad, Sergio García Blas, Arancha Ruescas, Agustín Fernández-Cisnal, and Albert Ariza-Solé
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IDI, integrated discrimination improvement ,medicine.medical_specialty ,Acute coronary syndrome ,030204 cardiovascular system & hematology ,03 medical and health sciences ,Grip strength ,0302 clinical medicine ,Weight loss ,Internal medicine ,medicine ,Hospital discharge ,030212 general & internal medicine ,cNRI, continuous net reclassification improvement ,lcsh:R5-920 ,business.industry ,Hazard ratio ,medicine.disease ,HR, hazard ratio ,Frailty assessment ,Gait speed ,GRACE, Global Registry of Acute Coronary Events ,Malnutrition ,Original Article ,medicine.symptom ,business ,lcsh:Medicine (General) - Abstract
Objective: To evaluate the 5 components of the Fried frailty phenotype (self-reported unintentional weight loss, physical activity questionnaire, gait speed, grip strength, and self-reported exhaustion) for long-term outcomes in elderly survivors of acute coronary syndrome. Methods: A total of 342 consecutive patients (from October 1, 2010, to February 1, 2012) were included. The 5 components of the Fried score and albumin concentration, as malnutrition index, were assessed before hospital discharge. Patients were followed up until April 2020 (median follow-up, 8.7 years). The end point was postdischarge all-cause mortality. Results: Mean ± SD age was 77±7 years and mean ± SD Fried score was 2.0±1.1 points. A total of 216 (63%) patients died. After adjusting for clinical covariates, the Fried phenotype was associated with mortality (per points, hazard ratio [HR], 1.35; 95% CI, 1.17 to 1.57; P
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- 2020
157. The impact of optimal medical therapy on patients with recurrent acute myocardial infarction: Subanalysis from the BleeMACS study
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Dongfeng Zhang, Zenon Huczek, Oliver Kalpak, Wouter J. Kikkert, José P.S. Henriques, José Ramón González-Juanatey, Fabrizio D'Ascenzo, Masa-aki Kawashiri, Shaoping Nie, Luis C. L. Correia, Claudio Moretti, Dimitrios Alexopoulos, Iván J. Núñez-Gil, Xiantao Song, Danielle A. Southern, Tetsuma Kawaji, Toshiharu Fujii, Emad Abu-Assi, Christoph Liebetrau, Stephen B. Wilton, Sergio Raposeiras-Roubín, Jorge Saucedo, Albert Ariza-Solé, Cardiology, and ACS - Atherosclerosis & ischemic syndromes
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Acute coronary syndrome ,medicine.medical_specialty ,Statin ,medicine.drug_class ,medicine.medical_treatment ,Myocardial Infarction ,Angiotensin-Converting Enzyme Inhibitors ,Acute myocardial infarction ,030204 cardiovascular system & hematology ,Percutaneous coronary intervention ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Clinical endpoint ,Humans ,Registries ,cardiovascular diseases ,030212 general & internal medicine ,Myocardial infarction ,Acute Coronary Syndrome ,Recurrent myocardial infarction ,Optimal medical therapy ,Aspirin ,business.industry ,medicine.disease ,Treatment Outcome ,Heart failure ,Propensity score matching ,Cardiology and Cardiovascular Medicine ,business ,medicine.drug - Abstract
Background: Acute myocardial infarction (AMI) recurrence is still high despite great progress in secondary prevention. Patients with recurrent AMI suffer worse prognosis compared to those with first AMI. The objective was to evaluate the effect of optimal medical therapy (OMT) on these patients with recurrent AMI. Methods and results: Sub-analysis was performed including 13,343 patients with AMI from the international multicenter Bleeding complications in a Multicenter registry of patients discharged with diagnosis of Acute Coronary Syndrome (BleeMACS) registry. OMT was defined as the combination of aspirin, any P2Y12 inhibitor, statin, angiotensin converting enzyme inhibitor/angiotensin receptor blocker, and beta-blocker. Among 1285 patients with prior AMI, 56.8% received OMT prescription. Patients receiving OMT suffered from less congestive heart failure, peripheral artery disease, malignancy, and bleeding history. Kaplan-Meier survival estimates revealed that OMT was strongly related to decreased in all-cause death (4.2% vs. 10.1%, p < .001) and the composite endpoint of death/re-AMI (11.1% vs. 16.9%, p = .005) at 1-year follow-up. OMT was the independent protect factor of primary endpoint even after adjusting for multiple possible confounders (HR, 0.46; 95% CI, 0.27–0.78; p = .004). However, no significant difference was observed regarding re-AMI between OMT and non-OMT groups. OMT also reduced all-cause death in patients with recurrent AMI after propensity score matching. Conclusions: The prescription of OMT was seriously insufficient in patients with recurrent AMI, especially high-risk patients, even though OMT was associated with improved prognosis. Further improvements in pharmacological therapy are needed to reduce subsequent recurrent events.
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- 2020
158. Estrategia invasiva precoz ajustada al riesgo en pacientes con síndrome coronario agudo sin elevación de segmento ST en Unidades de Cuidados Intensivos Cardiológicos
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Gil Bonet, Jordi Sans-Roselló, Teresa Oliveras, Miquel Gual, Angel Cequier, Antonia Sambola, Cosme García, Javier Cantalapiedra, Albert Ariza-Solé, Carlos Tomás, M. Pérez-Rodriguez, Rut Andrea, Jaime Aboal, Santiago Montero, David Viñas, Isabel Hernández, Isaac Llaó, J.A. Gómez-Hospital, and J. Ortiz
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03 medical and health sciences ,0302 clinical medicine ,030228 respiratory system ,business.industry ,Medicine ,030208 emergency & critical care medicine ,Critical Care and Intensive Care Medicine ,business ,Humanities - Abstract
Resumen Objetivo Las guias de practica clinica recomiendan la estrategia invasiva precoz ajustada al riesgo (EIPAR) en pacientes con sindrome coronario agudo sin elevacion del segmento ST (SCASEST). El objetivo fue analizar la aplicacion de la EIPAR, sus condicionantes e impacto sobre el pronostico en pacientes con SCASEST ingresados en Unidades de Cuidados Intensivos Cardiologicos (UCIC). Diseno Estudio de cohortes prospectivo. Ambito UCIC de 8 hospitales en Cataluna. Pacientes Pacientes consecutivos con SCASEST entre octubre del 2017 y marzo del 2018. El perfil de riesgo se definio mediante los criterios de la Sociedad Europea de Cardiologia. Intervenciones Se definio como EIPAR la realizacion de coronariografia en las primeras 6 h en pacientes de muy alto riesgo o en 24 h en pacientes de alto riesgo. Variables de interes Mortalidad/reingreso a los 6 meses. Resultados Se incluyo a 629 pacientes (edad media 66,6 anos), 225 (35,9%) de muy alto riesgo y 392 (62,6%) de alto riesgo. La estrategia invasiva fue mayoritaria (96,2%). La EIPAR se aplico en 284 pacientes (45,6%), especialmente pacientes mas jovenes, con menos comorbilidades. Estos pacientes presentaron menor estancia en UCIC y hospitalaria, asi como menor incidencia de SCA, revascularizaciones y menor incidencia de muerte/reingreso a 6 meses. Tras ajustar por factores de confusion, la asociacion entre adherencia y muerte/reingreso a 6 meses persistio de manera significativa (razon de riesgos: 0,66 [0,45-0,97] p = 0,035). Conclusiones La EIPAR se aplica en una minoria de SCASEST ingresados en UCIC, asociandose con una menor incidencia de eventos.
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- 2020
159. Impacto del tratamiento antitrombótico y los síndromes geriátricos en octogenarios con fibrilación auricular y cardiopatía isquémica. Fibrilación Auricular y Cardiopatía Isquémica en Longevos (FACIL)
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Raúl Moreno, Manuel Anguita, José Luis Ferreiro, Juan Sanchis, Sergio García Blas, Albert Ariza-Solé, Juan Ruiz García, Manuel Martínez-Sellés, Sonia Ibars, Ignacio Cruz-González, Inmaculada Roldán, Francisco Marcos Marín, Pablo Díez-Villanueva, Ana Ayesta, Antoni Carol Ruiz, Clara Bonanad Lozano, Angel Cequier, and Héctor García Pardo
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03 medical and health sciences ,Aging ,0302 clinical medicine ,Medicine (miscellaneous) ,030212 general & internal medicine ,030204 cardiovascular system & hematology ,Geriatrics and Gerontology - Abstract
Resumen Antecedentes y objetivos La prevalencia de fibrilacion auricular (FA) y cardiopatia isquemica ( C I) aumenta con la edad. Coexisten en hasta un 20% de los pacientes octogenarios, situacion que supone un desafio terapeutico. Los ensayos que han abordado este escenario, que incluyeron un porcentaje bajo de octogenarios, demostraron que la doble terapia (antiagregacion simple + anticoagulacion) en comparacion con la triple terapia (doble antiagregacion + anticoagulacion) se asocia menos eventos hemorragicos, especialmente con anticoagulantes orales de accion directa. Estos estudios no tenian potencia suficiente para detectar diferencias en eventos isquemicos. Por otro lado, aspectos prevalentes en la poblacion mayor, como los sindromes geriatricos, no se valoraron en estos estudios, y tampoco en la practica clinica habitual, desconociendose su impacto pronostico en este contexto clinico. Material y metodos Estudio observacional, prospectivo y multicentrico, que incluira pacientes ≥ 80 anos con FA y CI en Espana. Se valoraran las caracteristicas basales y los sindromes geriatricos, asi como la eleccion del tratamiento antitrombotico. El objetivo primario es conocer la mortalidad cardiovascular y por todas las causas a uno y tres anos. Resultados Este estudio permitira conocer las caracteristicas y el pronostico de pacientes octogenarios con FA y CI en nuestro medio, los factores implicados en la eleccion del tratamiento antitrombotico y la incidencia de eventos isquemicos y hemorragicos durante el seguimiento a corto y largo plazo. Conclusiones Nuestro trabajo contribuira a mejorar el conocimiento en terminos de seguridad y eficacia de las distintas opciones terapeuticas en pacientes mayores con FA y CI y su impacto pronostico.
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- 2020
160. Cardiogenic shock: approaching the truth
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Isaac, Llaó and Albert, Ariza-Solé
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- 2022
161. Cardiogenic shock due to left main related myocardial infarction: is revascularization enough?
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Francisco, Galván-Román, Elena, Puerto, Roberto, Martín-Asenjo, and Albert, Ariza-Solé
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- 2022
162. Usefulness of Impella support in different clinical settings in cardiogenic shock
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María Isabel, Barrionuevo-Sánchez, Albert, Ariza-Solé, Daniel, Ortiz-Berbel, José, González-Costello, Joan Antoni, Gómez-Hospital, Victòria, Lorente, Oriol, Alegre, Isaac, Llaó, José Carlos, Sánchez-Salado, Josep, Gómez-Lara, Arnau, Blasco-Lucas, and Josep, Comin-Colet
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The Impella pump has emerged as a promising tool in patients with cardiogenic shock (CS). Despite its attractive properties, there are scarce data on the specific clinical setting and the potential role of Impella devices in CS patients from routine clinical practice.This is an observational, retrospective, single center, cohort study. All consecutive patients with diagnosis of CS and undergoing support with Impella 2.5A total of 50 patients were included (median age: 59.3 ± 10 years). The most common cause of CS was acute coronary syndrome (ACS) (68%), followed by decompensation of previous cardiomyopathy (22%). A total of 13 patients (26%) had profound CS. Most patients (54%) improved pulmonary congestion at 48 h after Impella support. A total of 19 patients (38%) presented significant bleeding. In-hospital mortality was 42%. Among patients with profound CS (In this cohort of real-life CS patients, Impella devices were used in different settings, with different clinical profiles and management. Despite a significant rate of complications, mortality was acceptable and lower than those observed in other series.
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- 2022
163. One-Year Major Cardiovascular Events After Restrictive Versus Liberal Blood Transfusion Strategy in Patients With Acute Myocardial Infarction and Anemia: The REALITY Randomized Trial
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Jose R, Gonzalez-Juanatey, Gilles, Lemesle, Etienne, Puymirat, Gregory, Ducrocq, Marine, Cachanado, Joan Albert, Arnaiz, Manuel, Martínez-Sellés, Johanne, Silvain, Albert, Ariza-Solé, Emile, Ferrari, Gonzalo, Calvo, Nicolas, Danchin, Cristina, Avendano-Solá, Alexandra, Rousseau, Eric, Vicaut, Teba, Gonzalez-Ferrero, Philippe Gabriel, Steg, Tabassome, Simon, Universidade de Santiago de Compostela [Spain] (USC ), CHU Lille, Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U1011 (RNMCD), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Alliance française pour les essais cliniques cardio-vasculaires - French Alliance for Cardiovascular Trials (FACT), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Laboratoire de Recherche Vasculaire Translationnelle (LVTS (UMR_S_1148 / U1148)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Sorbonne Université (SU), Clinic Barcelona Hospital Universitari, Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition [CHU Pitié Salpêtrière] (IHU ICAN), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière [AP-HP], Groupe Action, Institut de cardiologie [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Bellvitge University Hospital [Barcelona, Spain], Hôpital Pasteur [Nice] (CHU), University of Barcelona, Hospital Universitario Puerta de Hierro-Majadahonda [Madrid, Spain], Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Diderot - Paris 7 (UPD7), Université Sorbonne Paris Cité (USPC), Royal Brompton Hospital, Centre de Ressources Biologiques APHP-SU (PASS-CRB-APHP-SU), Unité Mixte de Service Production et Analyse de données en Sciences de la vie et en Santé (PASS), and Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)
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anaemia ,Time Factors ,[SDV]Life Sciences [q-bio] ,major cardiovascular events ,Myocardial Infarction ,acute myocardial infarction ,Anemia ,Survival Analysis ,Cardiovascular Diseases ,Physiology (medical) ,Acute Disease ,Humans ,Blood Transfusion ,prognosis ,Cardiology and Cardiovascular Medicine ,transfusion - Abstract
International audience; No abstract available
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- 2022
164. Cardiogenic shock code 2023: expert document for a multidisciplinary organization that allows quality care
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Martínez-Sellés, Manuel, Hernández-Pérez, Francisco José, Uribarri, Aitor, Martín Villén, Luis, Zapata, Luis, Alonso, Joaquín C., Amat-Santos, Ignacio C., Ariza-Solé, Albert, Barrabés, José A., Barrio, José María, Canteli, Ángela, Alonso-Fernández-Gatta, Marta, Corbí Pascual, Miguel J., Díaz, Domingo, Crespo-Leiro, María Generosa, de la Torre-Hernández, José María, Ferrera, Carlos, García González, Martín J., García-Carreño, Jorge, García-Guereta, Luis, García Quintana, Antonio, Jorge Pérez, Pablo, González-Juanatey, J.R., López de Sá, Esteban, Sánchez, Pedro Luis, Monteagudo, María, Palomo López, Nora, Reyes, Guillermo, Rosell, Fernando, Solla-Buceta, Miguel, Segovia-Cubero, Javier, Sionis Green, Alessandro, Stepanenko, Alexander, Iglesias Álvarez, Diego, Viana Tejedor, Ana, Voces, Roberto, Fuset Cabanes, María Paz, Gimeno Costa, José Ricardo, Díaz, José, Fernández-Avilés, Francisco, Martínez-Sellés, Manuel, Hernández-Pérez, Francisco José, Uribarri, Aitor, Martín Villén, Luis, Zapata, Luis, Alonso, Joaquín C., Amat-Santos, Ignacio C., Ariza-Solé, Albert, Barrabés, José A., Barrio, José María, Canteli, Ángela, Alonso-Fernández-Gatta, Marta, Corbí Pascual, Miguel J., Díaz, Domingo, Crespo-Leiro, María Generosa, de la Torre-Hernández, José María, Ferrera, Carlos, García González, Martín J., García-Carreño, Jorge, García-Guereta, Luis, García Quintana, Antonio, Jorge Pérez, Pablo, González-Juanatey, J.R., López de Sá, Esteban, Sánchez, Pedro Luis, Monteagudo, María, Palomo López, Nora, Reyes, Guillermo, Rosell, Fernando, Solla-Buceta, Miguel, Segovia-Cubero, Javier, Sionis Green, Alessandro, Stepanenko, Alexander, Iglesias Álvarez, Diego, Viana Tejedor, Ana, Voces, Roberto, Fuset Cabanes, María Paz, Gimeno Costa, José Ricardo, Díaz, José, and Fernández-Avilés, Francisco
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[Abstract] Despite the efforts made to improve the care of cardiogenic shock (CS) patients, including the development of mechanical circulatory support (MCS), the prognosis of these patients continues to be poor. In this context, CS code initiatives arise, based on providing adequate, rapid, and quality care to these patients. In this multidisciplinary document we try to justify the need to implement the SC code, defining its structure/organization, activation criteria, patient flow according to care level, and quality indicators. Our specific purposes are: a) to present the peculiarities of this condition and the lessons of infarction code and previous experiences in CS; b) to detail the structure of the teams, their logistics and the bases for the management of these patients, the choice of the type of MCS, and the moment of its implantation, and c) to address challenges to SC code implementation, including the uniqueness of the pediatric SC code. There is an urgent need to develop protocolized, multidisciplinary, and centralized care in hospitals with a large volume and experience that will minimize inequity in access to the MCS and improve the survival of these patients. Only institutional and structural support from the different administrations will allow optimizing care for CS., [Resumen] Pese a los esfuerzos realizados para mejorar la atención al shock cardiogénico (SC), incluyendo el desarrollo de dispositivos de asistencia circulatoria mecánica (ACM), su pronóstico continúa siendo desfavorable. En este contexto surgen iniciativas de código SC, basadas en proporcionar una asistencia rápida y de calidad a estos pacientes. Este documento multidisciplinario trata de justificar la necesidad de implantar el código SC, definiendo su estructura/organización, criterios de activación, flujo de pacientes según nivel asistencial e indicadores de calidad. Sus propósitos concretos son: a) presentar las peculiaridades de esta enfermedad y el aprendizaje del código infarto y de experiencias previas en SC; b) detallar las bases para el abordaje de estos pacientes, la estructura de los equipos, su logística, la elección del tipo de ACM y el momento de su implante, y c) abordar los desafíos para la implantación del código SC, como la singularidad del código SC pediátrico. Urge desarrollar una asistencia protocolizada, multidisciplinaria y centralizada en hospitales con gran volumen y experiencia que permita minimizar la inequidad en el acceso a la ACM y mejorar la supervivencia de estos enfermos. Solo el apoyo institucional y estructural de las distintas administraciones permitirá optimizar la atención al SC.
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- 2022
165. Código shock cardiogénico 2023: documento de expertos para una organización multidisciplinaria que permita una atención de calidad
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Martínez-Sellés, Manuel, Hernández-Pérez, Francisco José, Uribarri, Aitor, Martín Villén, Luis, Zapata, Luis, Alonso, Joaquín C., Amat-Santos, Ignacio C., Ariza-Solé, Albert, Barrabés, José A., Barrio, José María, Canteli, Ángela, Alonso-Fernández-Gatta, Marta, Corbí Pascual, Miguel J., Díaz, Domingo, Crespo-Leiro, María Generosa, de la Torre-Hernández, José María, Ferrera, Carlos, García González, Martín J., García-Carreño, Jorge, García-Guereta, Luis, García Quintana, Antonio, Jorge Pérez, Pablo, González-Juanatey, J.R., López de Sá, Esteban, Sánchez, Pedro Luis, Monteagudo, María, Palomo López, Nora, Reyes, Guillermo, Rosell, Fernando, Solla-Buceta, Miguel, Segovia-Cubero, Javier, Sionis Green, Alessandro, Stepanenko, Alexander, Iglesias Álvarez, Diego, Viana Tejedor, Ana, Voces, Roberto, Fuset Cabanes, María Paz, Gimeno Costa, José Ricardo, Díaz, José, Fernández-Avilés, Francisco, Martínez-Sellés, Manuel, Hernández-Pérez, Francisco José, Uribarri, Aitor, Martín Villén, Luis, Zapata, Luis, Alonso, Joaquín C., Amat-Santos, Ignacio C., Ariza-Solé, Albert, Barrabés, José A., Barrio, José María, Canteli, Ángela, Alonso-Fernández-Gatta, Marta, Corbí Pascual, Miguel J., Díaz, Domingo, Crespo-Leiro, María Generosa, de la Torre-Hernández, José María, Ferrera, Carlos, García González, Martín J., García-Carreño, Jorge, García-Guereta, Luis, García Quintana, Antonio, Jorge Pérez, Pablo, González-Juanatey, J.R., López de Sá, Esteban, Sánchez, Pedro Luis, Monteagudo, María, Palomo López, Nora, Reyes, Guillermo, Rosell, Fernando, Solla-Buceta, Miguel, Segovia-Cubero, Javier, Sionis Green, Alessandro, Stepanenko, Alexander, Iglesias Álvarez, Diego, Viana Tejedor, Ana, Voces, Roberto, Fuset Cabanes, María Paz, Gimeno Costa, José Ricardo, Díaz, José, and Fernández-Avilés, Francisco
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[Resumen] Pese a los esfuerzos realizados para mejorar la atención al shock cardiogénico (SC), incluyendo el desarrollo de dispositivos de asistencia circulatoria mecánica (ACM), su pronóstico continúa siendo desfavorable. En este contexto surgen iniciativas de código SC, basadas en proporcionar una asistencia rápida y de calidad a estos pacientes. Este documento multidisciplinario trata de justificar la necesidad de implantar el código SC, definiendo su estructura/organización, criterios de activación, flujo de pacientes según nivel asistencial e indicadores de calidad. Sus propósitos concretos son: a) presentar las peculiaridades de esta enfermedad y el aprendizaje del código infarto y de experiencias previas en SC; b) detallar las bases para el abordaje de estos pacientes, la estructura de los equipos, su logística, la elección del tipo de ACM y el momento de su implante, y c) abordar los desafíos para la implantación del código SC, como la singularidad del código SC pediátrico. Urge desarrollar una asistencia protocolizada, multidisciplinaria y centralizada en hospitales con gran volumen y experiencia que permita minimizar la inequidad en el acceso a la ACM y mejorar la supervivencia de estos enfermos. Solo el apoyo institucional y estructural de las distintas administraciones permitirá optimizar la atención al SC., [Abstract] Despite the efforts made to improve the care of cardiogenic shock (CS) patients, including the development of mechanical circulatory support (MCS), the prognosis of these patients continues to be poor. In this context, CS code initiatives arise, based on providing adequate, rapid, and quality care to these patients. In this multidisciplinary document we try to justify the need to implement the SC code, defining its structure/organization, activation criteria, patient flow according to care level, and quality indicators. Our specific purposes are: a) to present the peculiarities of this condition and the lessons of infarction code and previous experiences in CS; b) to detail the structure of the teams, their logistics and the bases for the management of these patients, the choice of the type of MCS, and the moment of its implantation, and c) to address challenges to SC code implementation, including the uniqueness of the pediatric SC code. There is an urgent need to develop protocolized, multidisciplinary, and centralized care in hospitals with a large volume and experience that will minimize inequity in access to the MCS and improve the survival of these patients. Only institutional and structural support from the different administrations will allow optimizing care for CS.
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- 2022
166. Prognosis of cardiogenic shock secondary to culprit left main coronary artery lesion‐related myocardial infarction.
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Galván‐Román, Francisco, Fernández‐Herrero, Ignacio, Ariza‐Solé, Albert, Sánchez‐Salado, José Carlos, Puerto, Elena, Lorente, Victòria, Gómez‐Lara, Josep, Martín‐Asenjo, Roberto, Gómez‐Hospital, Joan A., and Comín‐Colet, Josep
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CARDIOGENIC shock ,CORONARY arteries ,HEART assist devices ,MYOCARDIAL infarction ,PERCUTANEOUS coronary intervention ,ARTIFICIAL blood circulation ,PROGNOSIS - Abstract
Aims: This study aimed to assess, in patients with cardiogenic shock secondary to unprotected left main coronary artery‐related myocardial infarction (ULMCA‐related AMICS), the incidence and predictors of no recovery of left ventricular function during the admission. Methods and results: This was an observational study conducted at two tertiary care centres (2012–20). The main outcome measured was death or requirement for heart transplantation (HT) or left ventricular assist devices (LVAD) during the admission. A total of 70 patients were included. Percutaneous coronary intervention (PCI) was successful in 53/70 patients (75.7%). The combined endpoint of death or requirement of HT or LVAD during the admission occurred in 41/70 patients (58.6%). The highest incidence of the primary endpoint was observed among patients with profound shock and occluded left main coronary artery (LMCA) (20/23, 87%, P < 0.001). Although a successful PCI reduced the incidence of the event in the whole cohort (51.9% vs. 82.4% in failed PCI, P = 0.026), this association was not observed among this last group of complex patients (86.7% vs. 87.5% in failed PCI, P = 0.731). The predictive model included left ventricular ejection fraction, baseline ULMCA Thrombolysis In Myocardial Infarction flow, and severity of shock and showed an optimal ability for predicting death or requirements for HT or LVAD during the admission (area under the curve 0.865, P < 0.001). Conclusions: ULMCA‐related AMICS was associated with a high in‐hospital mortality or need for HT or LVAD. Prognosis was especially poor among patients with profound shock and baseline occluded LMCA, with a low probability of recovery regardless of successful PCI. [ABSTRACT FROM AUTHOR]
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- 2023
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167. Correction to: Real-World Data of Prasugrel vs. Ticagrelor in Acute Myocardial Infarction: Results from the RENAMI Registry
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De Fillippo, Ovidio, Cortese, Martina, D´Ascenzo, Fabrizio, Raposeiras-Roubin, Sergio, Abu-Assi, Emad, Kinnaird, Tim, Ariza-Solé, Albert, Manzano-Fernández, Sergio, Templin, Christian, Velicki, Lazar, Xanthopoulou, Ioanna, Cerrato, Enrico, Rognoni, Andrea, Boccuzzi, Giacomo, Montefusco, Antonio, Montabone, Andrea, Taha, Salma, Durante, Alessandro, Gili, Sebastiano, Magnani, Giulia, Autelli, Michele, Grosso, Alberto, Blanco, Pedro Flores, Garay, Alberto, Quadri, Giorgio, Varbella, Ferdinando, Queija, Berenice Caneiro, Paz, Rafael Cobas, Fernández, María Cespón, Pousa, Isabel Muñoz, Gallo, Diego, Morbiducci, Umberto, Dominguez-Rodriguez, Alberto, Valdés, Mariano, Cequier, Angel, Alexopoulos, Dimitrios, Iñiguez-Romo, Andrés, and Rinaldi, Mauro
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- 2019
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168. Dynamics of Emergency Cardiovascular Hospital Admissions and In-Hospital Mortality During the COVID-19 Pandemic: Time Series Analysis and Impact of Socioeconomic Factors
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Álvarez-Martín, Claudia, primary, Ribera, Aida, additional, Marsal, Josep Ramon, additional, Ariza-Solé, Albert, additional, Pérez-Hoyos, Santiago, additional, Oristrell, Gerard, additional, Soriano-Colomé, Toni, additional, Romaguera, Rafael, additional, Pijoan, Jose Ignacio, additional, Lidón, Rosa M., additional, Mauri, Josepa, additional, and Ferreira-González, Ignacio, additional
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- 2022
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169. Evaluación por sorpresa de las competencias en soporte vital básico del personal sanitario del área de cardiología de un hospital de tercer nivel
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Castillo García, Jordi, primary, Barrionuevo Sánchez, María Isabel, additional, Sánchez-Salado, José Carlos, additional, Molina Mazón, Carlos-Santos, additional, Arbonés Arqué, Daniel, additional, and Ariza-Solé, Albert, additional
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- 2022
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170. Evaluation of the Use of Dual Antiplatelet Therapy beyond the First Year after Acute Coronary Syndrome
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Bonanad, Clara, primary, Raposeiras-Roubin, Sergio, additional, García-Blas, Sergio, additional, Núñez-Gil, Iván, additional, Vergara-Uzcategui, Carlos, additional, Díez-Villanueva, Pablo, additional, Bañeras, Jordi, additional, Badía Molins, Clara, additional, Aboal, Jaime, additional, Carreras, Jose, additional, Bodi, Vicente, additional, Gabaldón-Pérez, Ana, additional, Mateus-Porta, Gemma, additional, Parada Barcia, Jose, additional, Martínez-Sellés, Manuel, additional, Chorro, Francisco, additional, and Ariza-Solé, Albert, additional
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- 2022
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171. CLINICAL CORRELATES OF ISCHEMIC AND BLEEDING RISK IN PATIENTS WITH A PRIOR MYOCARDIAL INFARCTION TREATED WITH EXTENDED DUAL ANTIPLATELET THERAPY WITH TICAGRELOR 60 MG: INSIGHTS FROM ALETHEIA, A MULTI-COUNTRY OBSERVATIONAL STUDY
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Bonaca, Marc P., primary, Lesén, Eva, additional, Giannitsis, Evangelos, additional, Jernberg, Tomas, additional, Maggioni, Aldo Pietro, additional, Ariza-Solé, Albert, additional, Berg, Jurrien M. Ten, additional, Bhalla, Narinder, additional, and Storey, Robert F., additional
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- 2022
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172. Ethical considerations in elderly patients with acute coronary syndrome
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Ayesta, Ana, primary, Bonanad, Clara, primary, Díez-Villanueva, Pablo, primary, García-Blas, Sergio, primary, Ariza-Solé, Albert, primary, and Martínez-Sellés, Manuel, primary
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- 2022
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173. Incidence, predictors and prognostic impact of intracranial bleeding within the first year after an acute coronary syndrome in patients treated with percutaneous coronary intervention
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José Ramón González-Juanatey, Andrés Íñiguez-Romo, Sergio Raposeiras-Roubín, Jing-Yao Fan, Zenon Huczek, Yan Yan, Berenice Caneiro Queija, María Cespón Fernández, José María García-Acuña, María Castiñeira-Busto, Fabrizio D'Ascenzo, Jorge F. Saucedo, Toshiharu Fujii, José P.S. Henriques, Kenji Sakata, Masakazu Yamagishi, Wouter J. Kikkert, Sasko Kedev, Emad Abu-Assi, Luis C. L. Correia, Danielle A. Southern, Stephen B. Wilton, Tetsuma Kawaji, Dimitrios Alexopoulos, Masa-aki Kawashiri, Krzysztof J. Filipiak, Claudio Moretti, Cristina Barreiro Pardal, Yuji Ikari, Yalei Chen, Xiao Wang, Elena López Rodríguez, Takuya Nakahayshi, Isabel Muñoz-Pousa, Xiantao Song, Ioanna Xanthopoulou, Michal Kowara, Belén Terol, Fiorenzo Gaita, Albert Ariza-Solé, Shaoping Nie, Neriman Osman, Iván J. Núñez-Gil, Hiroki Shiomi, Dongfeng Zhang, Rafael Cobas Paz, Alberto Garay, Helge Möllmann, Christoph Liebetrau, ACS - Atherosclerosis & ischemic syndromes, and Cardiology
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Male ,medicine.medical_specialty ,Acute coronary syndrome ,Percutaneous ,medicine.medical_treatment ,Intracranial haemorrhage ,030204 cardiovascular system & hematology ,Global Health ,Critical Care and Intensive Care Medicine ,Risk Assessment ,acute coronary syndrome ,03 medical and health sciences ,0302 clinical medicine ,percutaneous coronary intervention ,Risk Factors ,Internal medicine ,medicine ,Humans ,In patient ,Registries ,030212 general & internal medicine ,Aged ,business.industry ,Incidence ,Incidence (epidemiology) ,Percutaneous coronary intervention ,General Medicine ,Thrombolysis ,Prognosis ,medicine.disease ,Cardiology ,Female ,Cardiology and Cardiovascular Medicine ,business ,Intracranial Hemorrhages ,Intracranial bleeding - Abstract
Background: The rate of intracranial haemorrhage after an acute coronary syndrome has been studied in detail in the era of thrombolysis; however, in the contemporary era of percutaneous coronary intervention, most of the data have been derived from clinical trials. With this background, we aim to analyse the incidence, timing, predictors and prognostic impact of post-discharge intracranial haemorrhage in patients with acute coronary syndrome undergoing percutaneous coronary intervention. Methods: We analysed data from the BleeMACS registry (patients discharged for acute coronary syndrome and undergoing percutaneous coronary intervention from Europe, Asia and America, 2003–2014). Analyses were conducted using a competing risk framework. Uni and multivariate predictors of intracranial haemorrhage were assessed using the Fine–Gray proportional hazards regression analysis. The endpoint was 1-year post-discharge intracranial haemorrhage. Results: Of 11,136 patients, 30 presented with intracranial haemorrhage during the first year (0.27%). The median time to intracranial haemorrhage was 150 days (interquartile range 55.7–319.5). The fatality rate of intracranial haemorrhage was very high (30%). After multivariate analysis, only age (subhazard ratio 1.05, 95% confidence interval 1.01–1.07) and prior stroke/transient ischaemic attack (hazard ratio 3.29, 95% confidence interval 1.36–8.00) were independently associated with a higher risk of intracranial haemorrhage. Hypertension showed a trend to associate with higher intracranial haemorrhage rate. The combination of older age (⩾75 years), prior stroke/transient ischaemic attack, and/or hypertension allowed us to identify most of the patients with intracranial haemorrhage (86.7%). The annual rate of intracranial haemorrhage was 0.1% in patients with no risk factors, 0.2% in those with one factor, 0.6% in those with two factors and 1.3% in those with three factors. Conclusion: The incidence of intracranial haemorrhage in the first year after an acute coronary syndrome treated with percutaneous coronary intervention is low. Advanced age, previous stroke/transient ischaemic attack, and hypertension are the main predictors of increased intracranial haemorrhage risk.
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- 2020
174. Coronavirus: la emergencia geriátrica de 2020. Documento conjunto de la Sección de Cardiología Geriátrica de la Sociedad Española de Cardiología y la Sociedad Española de Geriatría y Gerontología
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J. Sanchis Forés, Ana Ayesta, Albert Ariza-Solé, Pablo Díez-Villanueva, Sergio García-Blas, M.T. Vidán-Austiz, Juan Sanchis Forés, María Teresa Vidán-Austiz, Manuel Martínez-Sellés, P. Díez-Villanueva, S. García-Blas, F Formiga, Clara Bonanad, Francisco José Tarazona-Santabalbina, Francesc Formiga, F.J. Tarazona-Santabalbina, and A. Ariza-Sole
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Gerontology ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,Gerontología ,Pneumonia, Viral ,Enfermedad cardiovascular ,Cardiology ,Disease ,030204 cardiovascular system & hematology ,medicine.disease_cause ,Corrections ,Article ,Betacoronavirus ,03 medical and health sciences ,Geriatric cardiology ,0302 clinical medicine ,Clinical Protocols ,Internal medicine ,Pandemic ,medicine ,Humans ,Pandemics ,Societies, Medical ,Aged ,Sistema cardiovascular ,Coronavirus ,Geriatrics ,SARS-CoV-2 ,business.industry ,Worldwide emergency ,Mortality rate ,Age Factors ,COVID-19 ,General Medicine ,medicine.disease ,Comorbidity ,Geriatría ,Spain ,Coronavirus Infections ,business ,Virología - Abstract
La infección por SARS-CoV-2, denominada COVID-19 (Coronavirus Infectious Disease-19), es una enfermedad desconocida hasta diciembre de 2019 a la que nos enfrentamos en España desde el 31 de enero de 2020 —fecha del primer caso diagnosticado en nuestro país— y que ya ha causado la muerte de 7.340 personas (a 30 de marzo de 2020), sobre todo mayores. Es importante tener en cuenta que, dado que la información evoluciona con extremada rapidez en este campo, lo expuesto en el presente documento puede estar sujeto a modificaciones. La población de mayor edad es especialmente susceptible a la infección por COVID-19, así como a desarrollar criterios de gravedad. Este aumento de morbimortalidad en el paciente mayor se ha asociado tanto con las comorbilidades, especialmente la enfermedad cardiovascular, como con la situación de fragilidad, que conlleva una respuesta inmunológica más pobre. La situación actual, tanto por los países afectados como por el número de casos, constituye una pandemia y supone una emergencia sanitaria de primer nivel. Como España es uno de los países más envejecidos del mundo, la COVID-19 se ha convertido en una emergencia geriátrica. El presente documento se ha elaborado conjuntamente entre la Sección de Cardiología Geriátrica de la Sociedad Española de Cardiología y la Sociedad Española de Geriatría y Gerontología. Sin financiación 4.753 JCR (2020) Q2, 45/142 Cardiac & Cardiovascular Systems 0.455 SJR (2020) Q3, 202/349 Cardiology and Cardiovascular Medicine No data IDR 2020 UEM
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- 2020
175. Tendencias en el tratamiento del shock cardiogénico e impacto pronóstico del tipo de centros tratantes
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Angela Canteli, Manuel Martínez-Sellés, José L. Bernal, Esteban López-de-Sá, Marta Ruiz-Lera, José C. Sánchez-Salado, Héctor Bueno, Nicolás Manito, Alessandro Sionis, Angel Cequier, Rosa María Lidón, Javier Segovia, Isaac Llaó, Oriol Alegre, Ana Viana-Tejedor, Cristina Castrillo, Cristina Fernández, José González-Costello, Javier Elola, Fernando Worner, Victòria Lorente, Albert Ariza-Solé, and Virginia Burgos
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03 medical and health sciences ,0302 clinical medicine ,business.industry ,Medicine ,030204 cardiovascular system & hematology ,Cardiology and Cardiovascular Medicine ,business ,Humanities - Abstract
Resumen Introduccion y objetivos Las guias recomiendan centralizar la atencion del shock cardiogenico (SC) en centros altamente especializados. El objetivo de este estudio fue evaluar la asociacion entre las caracteristicas de los centros tratantes y la mortalidad en el SC secundario a infarto de miocardio con elevacion del segmento ST (IAMCEST). Metodos Se seleccionaron los episodios de alta con diagnostico de SC-IAMCEST entre 2003-2015 del Conjunto Minimo Basico de Datos del Sistema Nacional de Salud espanol. Los centros se clasificaron segun disponibilidad de servicio de cardiologia, laboratorio de hemodinamica, cirugia cardiaca y disponibilidad de Unidad de Cuidados Intensivos Cardiologicos (UCIC). La variable objetivo principal fue la mortalidad hospitalaria. Resultados Se identificaron 19.963 episodios. La edad media fue de 73,4 ± 11,8 anos. La proporcion de pacientes tratados en hospitales con laboratorio de hemodinamica y cirugia cardiaca aumento del 38,4% en 2005 al 52,9% en 2015; p Conclusiones La proporcion de pacientes con SC-IAMCEST tratados en centros altamente especializados aumento, mientras que la mortalidad disminuyo a lo largo del periodo de estudio. La revascularizacion y el ingreso en UCIC se asociaron con mejores resultados.
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- 2020
176. Impact of Diabetes Mellitus and Frailty on Long-Term Outcomes in Elderly Patients with Acute Coronary Syndromes
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Manuel Martínez-Sellés, Oriol Rodríguez-Queraltó, Miguel Corbí, Cinta Llibre, Francisco Marcos Marín, Pablo Díez-Villanueva, Lourdes Vicent, Oriol Alegre, Clara Bonanad, Eva Bernal, J. Angel Perez-Rivera, Antonio Carol, F Formiga, Albert Ariza-Solé, Juan Sanchis, and Jaime Aboal
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Male ,medicine.medical_specialty ,030309 nutrition & dietetics ,Frail Elderly ,Enfermedad cardiovascular ,Anciano ,Medicine (miscellaneous) ,frailty ,03 medical and health sciences ,Elderly ,0302 clinical medicine ,Older patients ,Internal medicine ,Diabetes mellitus ,Diabetes Mellitus ,Prevalence ,medicine ,Long term outcomes ,Humans ,Síndrome coronario agudo ,acute coronary syndromes ,Prospective Studies ,030212 general & internal medicine ,Acute Coronary Syndrome ,Prospective cohort study ,Aged, 80 and over ,0303 health sciences ,Nutrition and Dietetics ,Frailty ,business.industry ,Proportional hazards model ,Incidence (epidemiology) ,Diabetes ,Prognosis ,medicine.disease ,mortality ,Sistema endocrino ,diabetes mellitus ,Cohort ,Female ,Observational study ,Geriatrics and Gerontology ,business ,Ancianos - Abstract
Objectives Diabetes mellitus (DM) and frailty are common in older patients with acute coronary syndromes (ACS). No data exists about its prognostic impact on long-term outcomes and their possible interaction in this setting. Design Observational prospective study. Setting Multicenter registry conducted in 44 hospitals in Spain. Participants Consecutive patients with ACS aged 80≥years. Measurements A comprehensive geriatric evaluation was performed during hospitalization, including frailty assessment by the FRAIL score. The impact of DM and frailty on the incidence of mortality/readmission at 24 months was analysed by a Cox regression model. Results A total of 498 patients were included (mean age 84.3 years). Prevalence of previous DM was 199/498 (40.0%). The rate of frail patients was 135/498 (27.1%). The incidence of mortality/readmission was higher frail patients (HR 2.49) (both p
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- 2020
177. Rendimiento de la escala CardShock en pacientes con shock cardiogénico profundo tratados con membrana de oxigenación extracorpórea venoarterial
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Albert Ariza-Solé, J.C. Sánchez-Salado, Isaac Llaó, O. Alegre, L. Blázquez, and V. Lorente
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Gynecology ,medicine.medical_specialty ,business.industry ,medicine ,Critical Care and Intensive Care Medicine ,business - Published
- 2020
178. Predictive ability of the CardShock score in patients with profound cardiogenic shock undergoing venoarterial extracorporeal membrane oxygenation support
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V. Lorente, L. Blázquez, O. Alegre, Isaac Llaó, Albert Ariza-Solé, and J.C. Sánchez-Salado
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medicine.medical_specialty ,Text mining ,business.industry ,Cardiogenic shock ,Internal medicine ,medicine.medical_treatment ,medicine ,Extracorporeal membrane oxygenation ,Cardiology ,In patient ,medicine.disease ,business - Published
- 2020
179. Comments on the 2019 ESC guidelines on chronic coronary syndromes
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Antonia Sambola, Borja Ibáñez, Rut Andrea, Gemma Berga, José Antonio Blázquez, Victoria Delgado, José Luis Ferreiro, Felipe Navarro, Sergio Raposeiras-Roubin, Rafael Rodríguez Lecoq, Albert Ariza Solé, Manuel Barreiro Pérez, Esteban López de Sá, Amparo Martínez Monzonis, Raúl Moreno, Carolina Ortiz, Armando Pérez de Prado, Javier Torres Llergo, Fernando Arribas, Gemma Berga Congost, Héctor Bueno, Arturo Evangelista, Ignacio Ferreira-González, Manuel Jiménez Navarro, Francisco Marín, Leopoldo Pérez de Isla, Rafael Vázquez, Ana Viana-Tejedor, and Fernando Alfonso
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medicine.medical_specialty ,business.industry ,medicine ,General Medicine ,Intensive care medicine ,business - Published
- 2020
180. Consideraciones sobre el abordaje invasivo de la cardiopatía isquémica y estructural durante el brote de coronavirus COVID-19
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Pablo Jorge-Pérez, Rafael Romaguera, Virginia Burgos-Palacios, Esteban López-de-Sá, Alfonso Jurado-Román, Raúl Moreno, Albert Ariza-Solé, Ignacio Cruz-González, Agustín Fernández-Cisnal, and Soledad Ojeda
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covid-19 ,infarto ,prevención ,General Engineering ,pandemia ,cardiología intervencionista ,infección ,Internal medicine ,RC31-1245 ,angioplastia - Abstract
El brote actual de COVID-19 está obligando a los profesionales sanitarios a replantear de forma continua las indicaciones de cateterismo cardiaco. La optimización de recursos materiales y humanos, la prevención de contagios a profesionales y pacientes, así como la gestión de los tiempos de traslado, hace totalmente necesario reformular los protocolos previamente establecidos. El presente texto es un documento de consenso de la Asociación de Cardiología Intervencionista y la Asociación de Cardiopatía Isquémica y Cuidados Agudos Cardiovasculares de la Sociedad Española de Cardiología que pretende dar información al personal sanitario sobre las indicaciones de cateterismo diagnóstico o terapéutico durante la pandemia actual de COVID-19.
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- 2020
181. Selección de lo mejor del año 2019 en cardiopatía isquémica y cuidados críticos cardiovasculares
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Miriam Juárez Fernández, Aitor Uribarri, Esteban López-de-Sá, Iago Sousa-Casasnovas, Elisabete Alzola Martínez de Antoñana, Pablo Jorge Pérez, Albert Ariza Solé, and Roberto Martín-Asenjo
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Cardiology and Cardiovascular Medicine - Abstract
Resumen Han sido numerosos los estudios publicados en el campo de la cardiopatia isquemica y de los cuidados criticos cardiovasculares en este ultimo ano. Por este motivo, esta revision no pretende abarcar todos ellos, sino mas bien una seleccion de algunas publicaciones que a criterio subjetivo de los autores se consideran de interes.
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- 2020
182. Selección de lo mejor del año 2019 en cardiología geriátrica
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Pablo Díez-Villanueva, Antoni Carol Ruiz, Héctor García-Pardo, Clara Bonanad Lozano, F. Javier Martín-Sánchez, Eva Gallego González, Albert Ariza-Solé, and Alberto Esteban-Fernández
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Cardiology and Cardiovascular Medicine - Abstract
Resumen Durante el ultimo ano se han publicado numerosos trabajos centrados en el paciente mayor con enfermedad cardiovascular. En este texto repasamos algunos de estos trabajos, relacionados todos con el abordaje del paciente mayor en distintos escenarios clinicos. Hemos querido resaltar y prestar especial atencion a aspectos de gran relevancia clinica, dado su impacto pronostico, como la fragilidad, la comorbilidad o la polifarmacia, y centrarnos en como mejorar la atencion que proporcionamos a nuestros pacientes en distintos ambitos (urgencias, hospitalizacion, ambulatorio) y procesos concretos como la fibrilacion auricular, la insuficiencia cardiaca, las valvulopatias y los sindromes coronarios agudos.
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- 2020
183. Average daily ischemic versus bleeding risk in patients with ACS undergoing PCI: Insights from the BleeMACS and RENAMI registries
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Toshiharu Fujii, Emad Abu-Assi, Gaetano M. De Ferrari, Pedro Flores Blanco, Mariano Valdés, Sebastiano Gili, Lazar Velicki, Alessandro Durante, Ugo Fabrizio, José P.S. Henriques, Dimitrios Alexopoulos, Giulia Magnani, María Cespón Fernández, Fabrizio D'Ascenzo, Tim Kinnaird, Federico Gaido, Giacomo Boccuzzi, Salma Taha, Christian Templin, Giuseppe Biondi-Zoccai, Masa-aki Kawashiri, Christoph Liebetrau, Tetsuma Kawaji, Andrea Rognoni, Gregg W. Stone, Alberto Garay, Federica Bongiovanni, Zenon Huczek, José Ramón González-Juanatey, Alberto Dominguez-Rodriguez, Giorgio Quadri, Angel Cequier, Albert Ariza-Solé, Berenice Caneiro Queija, Sergio Manzano-Fernández, Stephen B. Wilton, Luis C. L. Correia, Michele Autelli, Rafael Cobas Paz, Andrea Montabone, Isabel Muñoz Pousa, Pierluigi Omedè, Andrés Íñiguez-Romo, Sergio Raposeiras-Roubín, Carloalberto Biolè, Alberto Grosso, Iván J. Núñez-Gil, Ioanna Xanthopoulou, Umberto Morbiducci, Shaoping Nie, Xiantao Song, Sara Rettegno, Federico Conrotto, Diego Gallo, Enrico Cerrato, Cardiology, and ACS - Atherosclerosis & ischemic syndromes
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Male ,Ticagrelor ,Acute coronary syndrome ,medicine.medical_specialty ,Time Factors ,Prasugrel ,medicine.medical_treatment ,Hemorrhage ,030204 cardiovascular system & hematology ,03 medical and health sciences ,Percutaneous Coronary Intervention ,Postoperative Complications ,0302 clinical medicine ,Ischemia ,Recurrence ,Internal medicine ,medicine ,Humans ,In patient ,Registries ,030212 general & internal medicine ,Myocardial infarction ,Acute Coronary Syndrome ,Aged ,business.industry ,Percutaneous coronary intervention ,Middle Aged ,medicine.disease ,Clopidogrel ,Conventional PCI ,Cardiology ,ST Elevation Myocardial Infarction ,Female ,Cardiology and Cardiovascular Medicine ,business ,Prasugrel Hydrochloride ,Platelet Aggregation Inhibitors ,medicine.drug - Abstract
BACKGROUND The risk of recurrent ischemia and bleeding after percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) may vary during the first year of follow-up according to clinical presentation, and medical and interventional strategies. METHODS BleeMACS and RENAMI are 2 multicenter registries enrolling patients with ACS treated with PCI and clopidogrel, prasugrel, or ticagrelor. The average daily ischemic and bleeding risks (ADIR and ADBR) in the first year after PCI were the primary end points. The difference between ADBR and ADIR was calculated to estimate the potential excess of bleeding/ischemic events in a given period or specific subgroup. RESULTS A total of 19,826 patients were included. Overall, in the first year after PCI, the ADBR was 0.008085%, whereas ADIR was 0.008017% (P = .886). In the first 2 weeks ADIR was higher than ADBR (P = .013), especially in patients with ST-segment elevation myocardial infarction or incomplete revascularization. ADIR continued to be, albeit non-significantly, greater than ADBR up to the third month, whereas ADBR became higher, although not significantly, afterward. Patients with incomplete revascularization had an excess in ischemic risk (P = .003), whereas non-ST-segment elevation ACS patients and those on ticagrelor had an excess of bleeding (P = .012 and P = .022, respectively). CONCLUSIONS In unselected ACS patients, ADIR and ADBR occurred at similar rates within 1 year after PCI. ADIR was greater than ADBR in the first 2 weeks, especially in ST-segment elevation myocardial infarction patients and those with incomplete revascularization. In the first year, ADIR was higher than ADBR in patients with incomplete revascularization, whereas ADBR was higher in non-ST-segment elevation ACS patients and in those discharged on ticagrelor.
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- 2020
184. Impact of frailty and other geriatric syndromes on the clinical management and prognosis of elderly ambulatory patients with heart failure. A prospective and multicentre study
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Albert Ariza-Solé, Clara Bonanad Lozano, Jorge Salamanca, César Jiménez Méndez, Pablo Díez-Villanueva, Francisco Javier Martín-Sánchez, María T. Vidán, Manuel Martínez-Sellés, Fernando Alfonso, Francesc Formiga, Héctor Bueno, and Beatriz Terres
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Geriatría ,Tratamiento médico ,03 medical and health sciences ,Aging ,0302 clinical medicine ,Gerontología ,Enfermos cardíacos ,Enfermedad cardiovascular ,Medicine (miscellaneous) ,030212 general & internal medicine ,030204 cardiovascular system & hematology ,Geriatrics and Gerontology - Abstract
Antecedentes y objetivos La insuficiencia cardiaca (IC) es una enfermedad crónica frecuentemente asociada al envejecimiento. Disponemos de modelos predictivos basados en variables que asocian mal pronóstico y que sin embargo no incluyen condiciones habituales en el paciente mayor, como la fragilidad o la comorbilidad. Nuestro objetivo es conocer las características clínicas y epidemiológicas de una cohorte de pacientes mayores con IC ambulatoria seguidos por cardiología, la prevalencia de la fragilidad y otros síndromes geriátricos, así como su impacto pronóstico, y conocer si su consideración mejora la capacidad predictiva de los modelos de riesgo utilizados. Material y métodos Estudio observacional, prospectivo y multicéntrico que incluirá 400 pacientes ≥ 75 años con IC crónica seguidos en hospital de día y consultas de IC de cardiología de hospitales terciarios españoles, a los que se realizará una valoración geriátrica integral y una predicción de eventos basada en los scores MAGGIC y BCN-Bio HF calculator. La variable de resultado principal es la mortalidad por cualquier causa y de origen cardiovascular a 1 y 3 años. Resultados Este estudio permitirá conocer las características y el pronóstico de pacientes ancianos con IC seguidos por cardiología en nuestro medio y la utilidad en población anciana de scores utilizados en la población general con IC crónica. Conclusión Nuestro trabajo es el primer estudio prospectivo que valorará la fragilidad y otros síndromes geriátricos de forma sistemática en el paciente anciano ambulatorio con IC en España seguido por cardiología, contribuyendo a mejorar el conocimiento de su prevalencia e impacto en nuestros pacientes. Background and objectives Heart failure (HF) is a chronic disease that is often associated with ageing. There are predictive models based on variables that associate it with a poor prognosis, although those do not include common conditions in the elderly, such as frailty or comorbidity. The aim of this study is to determine the clinical and epidemiological characteristics of a cohort of elderly outpatients with HF followed-up by cardiologists. This will include a study of the prevalence of frailty and other geriatric syndromes, as well as their impact on the prognosis, and to evaluate whether these may improve predictive ability of such predictive models. Material and methods Observational, prospective, and multicentre study that will include 400 patients ≥ 75 years old with chronic HF followed-up in Spanish tertiary hospitals by cardiology specialists in HF. Patients will undergo a comprehensive geriatric assessment, and prediction of events will be performed based on MAGGIC (Meta-Analysis Global Group in Chronic Heart Failure) and Barcelona-Bio HF calculator scores. The primary endpoint is cardiovascular and overall mortality at 1 and 3 years follow-up. Results This study will assess both the characteristics and prognosis of elderly patients with HF followed-up by cardiologists in Spain and the applicability in the elderly population of scores used in the general population with chronic HF. Conclusion This is the first prospective study that will systematically assess frailty and other geriatric syndromes in the elderly outpatient with HF in Spain and followed-up by cardiologists, thus contributing to improve knowledge about both its prevalence and impact on our patients. Sin financiación No data JCR 2020 0.206 SJR (2020) Q4, 31/35 Aging No data IDR 2020 UEM
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- 2020
185. Coronary angiography in patients without ST-segment elevation following out-of-hospital cardiac arrest
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Ana, Viana-Tejedor, Rut, Andrea-Riba, Claudia, Scardino, Albert, Ariza-Solé, Jordi, Bañeras, Cosme, García-García, Manuel, Jiménez Mena, Monserrat, Vila, Manuel, Martínez-Sellés, Gemma, Pastor, José María, García Acuña, Pablo, Loma-Osorio, Juan Carlos, García Rubira, Pablo, Jorge Pérez, Pablo, Pastor, Carlos, Ferrera, Francisco J, Noriega, Natalia, Pérez Macías, Antonio, Fernández-Ortiz, and Julián, Pérez-Villacastín
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The role of emergency coronary angiography (CAG) and percutaneous coronary intervention (PCI) following out-of-hospital cardiac arrest (OHCA) in patients without ST-segment elevation myocardial infarction (STEMI) remains unclear. We aimed to assess whether emergency CAG and PCI would improve survival with good neurological outcome in this population.In this multicenter, randomized, open-label, investigator-initiated clinical trial, we randomly assigned 69 survivors of OHCA without STEMI to undergo immediate CAG or deferred CAG. The primary efficacy endpoint was a composite of in-hospital survival free of severe dependence. The safety endpoint was a composite of major adverse cardiac events including death, reinfarction, bleeding, and ventricular arrhythmias.A total of 66 patients were included in the primary analysis (95.7%). In-hospital survival was 62.5% in the immediate CAG group and 58.8% in the delayed CAG group (HR, 0.96; 95%CI, 0.45-2.09; P=.93). In-hospital survival free of severe dependence was 59.4% in the immediate CAG group and 52.9% in the delayed CAG group (HR, 1.29; 95%CI, 0.60-2.73; P=.4986). No differences were found in the secondary endpoints except for the incidence of acute kidney failure, which was more frequent in the immediate CAG group (15.6% vs 0%, P=.002) and infections, which were higher in the delayed CAG group (46.9% vs 73.5%, P=.003).In this underpowered randomized trial involving patients resuscitated after OHCA without STEMI, immediate CAG provided no benefit in terms of survival without neurological impairment compared with delayed CAG.gov Identifier: NCT02641626.
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- 2022
186. Ischemic-hemorrhagic balance in diabetic and non-diabetic patients after acute coronary syndrome
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Luis Manuel Domínguez-Rodríguez, Sergio Raposeiras-Roubín, Emad Abu-Assi, María Cespón-Fernández, María Melendo-Viu, Fabrizio D’Ascenzo, Tim Kinnaird, Albert Ariza-Solé, Sergio Manzano-Fernández, Christian Templin, Lazar Velicki, Ioanna Xanthopoulou, Enrico Cerrato, Giorgio Quadri, Andrea Rognoni, Giacome Boccuzzi, Andrea Montabone, Salma Taha, Alessandro Durante, Sebastiano Gili, Giulia Magnani, Michele Autelli, Alberto Grosso, Pedro Flores-Blanco, Alberto Garay, Ferdinando Varbella, Francesco Tommassini, Diego Gallo, Umberto Morbiducci, Alberto Domínguez-Rodríguez, Mariano Valdés, Ángel Cequier, Fiorenzo Gaita, Dimitrios Alexopoulos, and Andrés Íñiguez-Romo
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Cardiology and Cardiovascular Medicine - Published
- 2022
187. Risk factors and cardiovascular disease in the elderly
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Díez Villanueva, Pablo, Jiménez-Méndez, César, Bonanad, Clara, García-Blas, Sergio, Pérez-Rivera, Ángel, Allo, Gonzalo, García-Pardo, Héctor, Formiga Pérez, Francesc, Camafort Blanco, Miquel, Martínez Sellés, Manuel, Ariza Solé, Albert, and Ayesta, Ana
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Aging ,Diabetis ,Malalties cardiovasculars ,Factors de risc en les malalties ,Risk factors in diseases ,Calidad de vida ,Enfermedad cardiovascular ,Anciano ,Diabetes ,General Medicine ,Cardiovascular diseases ,Envelliment ,Hypertension ,Obesitat ,Hipertensió ,Obesity ,Cardiology and Cardiovascular Medicine ,Factores de riesgo - Abstract
Age is associated with increased cardiovascular risk factors and cardiovascular disease, which constitutes the leading cause of morbidity and mortality in elderly population. In this text we thoroughly review current evidence regarding the impact on cardiovascular disease of the most important cardiovascular risk factors, especially prevalent and common in the elderly population. Diagnosis and treatment approaches are also addressed, also highlighting the importance of adequate primary and secondary prevention and management. Also, the relationship between cardiovascular disease and some comorbidities and geriatric conditions, such as frailty, particularly common in the elderly, is reviewed, together with some other issues, less often addressed but closely related to ageing, such as genetics, structural and electrical heart changes and oxidative stress. All such questions are of great importance in the comprehensive approach of risk factors and cardiovascular disease in the elderly. Sin financiación 4.430 JCR (2021) Q2, 57/143 Cardiac & Cardiovascular Systems 0.590 SJR (2021) Q2, 158/356 Cardiology and Cardiovascular Medicine No data IDR 2021 UEM
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- 2022
188. Ethical considerations in elderly patients with acute coronary syndrome
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Manuel Martínez-Sellés, Albert Ariza-Solé, Sergio García-Blas, Pablo Díez-Villanueva, Clara Bonanad, and Ana Ayesta
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Enfermedad cardiovascular ,Anciano ,Beneficence ,General Medicine ,Comorbidity ,Medical ethics ,Malalties coronàries ,Ética médica ,Ètica mèdica ,Ageism ,Coronary diseases ,Principle-Based Ethics ,Patient Rights ,Social Justice ,Personal Autonomy ,Humans ,Ethics, Medical ,Síndrome coronario agudo ,Acute Coronary Syndrome ,Precision Medicine ,Cardiology and Cardiovascular Medicine ,Geriatric Assessment ,Aged ,Inutilidad médica - Abstract
Acute coronary syndrome (ACS) is one of the main causes of mortality and morbidity in the elderly. The prevalence of ACS increases with age and patients with advanced age have some co-morbidities that require an individualized approach, which includes a comprehensive geriatric assessment. Ageism is a matter of great concern. In this scenario, some ethical conflicts may arise which should be anticipated, considered, and solved. Clinicians will need to prioritize and allocate resources, to avoid futility/proportionality, which is not always easy to assess in these patients. This review aims to summarize the evidence regarding ethical conflicts that may arise in the management of patients with ACS and advanced age. We will discuss how to choose the best option (which frequently is not the only one) with the lowest risk for harm, considering and respecting the patients' decision. The four basic principles of bioethics (beneficence, non-maleficence, autonomy, and justice) are thoroughly reviewed, and discussed, regarding their role in the decision making process. Sin financiación 4.430 JCR (2021) Q2, 57/143 Cardiac & Cardiovascular Systems 0.590 SJR (2021) Q2, 158/356 Cardiology and Cardiovascular Medicine No data IDR 2020 UEM
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- 2022
189. Antithrombotic Therapy in Elderly Patients with Acute Coronary Syndromes
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Clara Bonanad, Francisca Esteve-Claramunt, Sergio García-Blas, Ana Ayesta, Pablo Díez-Villanueva, Jose-Ángel Pérez-Rivera, José Luis Ferreiro, Joaquim Cánoves, Francisco López-Fornás, Albert Ariza Solé, Sergio Raposerias, David Vivas, Regina Blanco, Daznia Bompart Berroterán, Alberto Cordero, Julio Núñez, Lorenzo Fácila, Iván J. Núñez-Gil, José Luis Górriz, Vicente Bodí, Manuel Martínez-Selles, Juan Miguel Ruiz Nodar, and Francisco Javier Chorro
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clopidogrel ,Heart diseases ,Gerontología ,Enfermedad cardiovascular ,General Medicine ,Cardiología ,Clorhidrato de prasugrel ,elderly ,antiplatelet therapy ,Malalties del cor ,acute coronary syndrome ,prasugrel ,ticagrelor ,Anticoagulants (Medicina) ,Síndrome coronario agudo ,Anticoagulants (Medicine) - Abstract
The treatment of acute coronary syndrome (ACS) in elderly patients continues to be a challenge because of the characteS.G.B.ristics of this population and the lack of data and specific recommendations. This review summarizes the current evidence about critical points of oral antithrombotic therapy in elderly patients. To this end, we discuss the peculiarities and differences reported referring to dual antiplatelet therapy (DAPT) in ACS management in elderly patients and what might be the best option considering these population characteristics. Furthermore, we analyze antithrombotic strategies in patients with atrial fibrillation (AF), with a particular focus on those cases that also present coronary artery disease (CAD). It is imperative to deepen our knowledge regarding the management of these challenging patients through real-world data and specifically designed geriatric studies to help resolve the questions remaining in their disease management. Instituto de Salud Carlos III / FEDER Founds (JR/21/00041, CIBERCV16/11/00486, PI20/00637) Generalitat Valencia, Conselleria d'Educació (PROMETEO/21/008) 4.242 JCR (2020) Q1, 39/167 Medicine, General & Internal 1.040 SJR (2021) Q1, 438/2489 Medicine (miscellaneous) No data IDR 2020 UEV
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- 2022
190. Evaluation of the Use of Dual Antiplatelet Therapy beyond the First Year after Acute Coronary Syndrome
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Clara Bonanad, Sergio Raposeiras-Roubin, Sergio García-Blas, Iván Núñez-Gil, Carlos Vergara-Uzcategui, Pablo Díez-Villanueva, Jordi Bañeras, Clara Badía Molins, Jaime Aboal, Jose Carreras, Vicente Bodi, Ana Gabaldón-Pérez, Gemma Mateus-Porta, Jose Antonio Parada Barcia, Manuel Martínez-Sellés, Francisco Javier Chorro, Albert Ariza-Solé, Institut Català de la Salut, [Bonanad C, García-Blas S] Cardiology Department, Hospital Clínico Universitario de Valencia, Valencia, Spain. Department of Cardiology, INCLIVA Biomedical Research Institute, Valencia, Spain. Department of Medicine, University of Valencia, Valencia, Spain. [Raposeiras-Roubin S] Cardiology Department, Hospital Universitario Álvaro Cunqueiro de Vigo, Vigo, Spain. [Núñez-Gil I, Vergara-Uzcategui C] Cardiology Department, Hospital Clínico San Carlos, Madrid, Spain. [Díez-Villanueva P] Cardiology Department, Hospital Universitario de la Princesa, Madrid, Spain. [Bañeras J, Badía Molins C] Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain, and Vall d'Hebron Barcelona Hospital Campus
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acciones y usos químicos::acciones farmacológicas::usos terapéuticos::fármacos hematológicos::inhibidores de la agregación plaquetaria [COMPUESTOS QUÍMICOS Y DROGAS] ,Malalties coronàries - Tractament ,Other subheadings::/therapy [Other subheadings] ,General Medicine ,Malalties coronàries ,Coronary diseases ,Ischemia ,Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Hematologic Agents::Platelet Aggregation Inhibitors [CHEMICALS AND DRUGS] ,enfermedades cardiovasculares::enfermedades cardíacas::isquemia miocárdica::síndrome coronario agudo [ENFERMEDADES] ,Isquèmia ,Plaquetes sanguínies - Trastorns ,dual antiplatelet therapy ,acute coronary syndrome ,ischemic risk ,Cardiovascular Diseases::Heart Diseases::Myocardial Ischemia::Acute Coronary Syndrome [DISEASES] ,Otros calificadores::/terapia [Otros calificadores] - Abstract
Acute coronary syndrome; Dual antiplatelet therapy; Ischemic risk Síndrome coronario agudo; Terapia antiplaquetaria dual; Riesgo isquémico Síndrome coronària aguda; Teràpia antiplaquetària dual; Risc isquèmic Clinical practice guidelines recommend extending dual antiplatelet therapy (DAPT) beyond 1 year after acute coronary syndrome (ACS) in patients with high ischemic risk and without high bleeding risk. The aim of this study was to identify variables associated with DAPT prolongation in a cohort of 1967 consecutive patients discharged after ACS without thrombotic or hemorrhagic events during the following year. The sample was stratified according to whether DAPT was extended beyond 1 year, and the factors associated with this strategy were analyzed. In 32.2% of the patients, DAPT was extended beyond 1 year. Overall, 770 patients (39.1%) were considered candidates for extended treatment based on PEGASUS criteria and absence of high bleeding risk, and DAPT was extended in 34.4% of them. The presence of a PEGASUS criterion was associated with extended DAPT in the univariate analysis, but not history of bleeding or a high bleeding risk. In the multivariate analysis, a history of percutaneous coronary intervention (odds ratio (OR) = 1.8, 95% confidence interval (CI) 1.4–2.4), stent thrombosis (OR = 3.8, 95% CI 1.7–8.9), coronary artery disease complexity (OR = 1.3, 95% CI 1.1–1.5), reinfarction (OR = 4.1, 95% CI 1.6–10.4), and clopidogrel use (OR = 1.3, 95% CI 1.1–1.6) were significantly associated with extended use. DAPT was extended in 32.2% of patients who survived ACS without thrombotic or hemorrhagic events. This percentage was 34.4% when the candidates were analyzed according to clinical guidelines. Neither the PEGASUS criteria nor the bleeding risk was independently associated with this strategy. This work was supported by “Instituto de Salud Carlos III” and “Fondos Europeos de Desarrollo Regional FEDER” [grant numbers JR/21/00041, PI20/00637 and CIBERCV16/11/00486] and by Conselleria de Educación – Generalitat Valenciana (PROMETEO/2021/008).
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- 2022
191. P513 Prospective study on patients’ satisfaction and impact on quality of life of corticosteroid therapy in patients with Inflammatory Bowel Disease
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M Navarro Llavat, O García-Bosch, J Castro-Poceiro, A Bargalló García, D Ruiz Arroyo, Y Navas Bravo, E Erice Muñoz, D Barquero Declara, A Mata Bilbao, M Martín Llahí, X Ariza Solé, C Hernández Ballesteros, A Juan Juan, K Bustamante Robles, C Berbel Comas, A Blasco Pelicano, M Albareda Riera, and E Domènech Morral
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Gastroenterology ,General Medicine - Abstract
Background Corticosteroids (Cs) remain the first-line therapy for moderate-to-severe flares in patients with inflammatory bowel disease (IBD), both Crohn’s disease (CD) and ulcerative colitis (UC). On the other hand, their use has been associated to multiple adverse events (AEs) in randomized controlled trials and registries. Nevertheless, recent studies have repeatedly observed that the use of Cs has not decreased in spite of the increasing availability of biological agents and new small molecules licensed for IBD. The impact of Cs therapy on patients’ quality of life (QoL) and the patients’ perception on Cs have not been properly assessed in IBD. The purpose of this study was to assess the impact of a standard Cs course on the patients’ QoL and their satisfaction with treatment. Methods A prospective, longitudinal and observational study was conducted in adult IBD. All subjects received the same standard Cs regimen: starting dose of 1mg/kg/day (maximum 60mg/day) and tapering after 14 days with 10mg per week until reach 20mg/day, thereafter reduction was 5mg per week. QoL was assessed by the IBDQ-9 questionnaire at baseline, week 4 and at the end of Cs. Treatment satisfaction was assessed by the TSQM1.4 questionnaire at week 4 and at the end of Cs. Results Sixty-three patients were included in the study (54% CD and 43% UC; mean age 38.5±14.9 years; 46%females). Cs therapy failed in 41% of cases (active disease upon Cs discontinuation or need for rescue therapy). AEs attributable to Cs were reported in 84.1%, the most frequent were dermatologic (acne and moon face) (60.3%), hypokalemia (44.8%) and poor quality of sleep (40%). Serious AEs were reported in 20,6%, mostly mild or moderate infections that resolved without sequelae. IBDQ-9 scores increased 12.4 and 13.5 points at 4 weeks and at the end of Cs, respectively (p Conclusion A standard Cs course significantly increases the QoL of patients with IBD. Furthermore, a high satisfaction with treatment was perceived by patients.
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- 2023
192. Rational and design of the Baseline Interatrial block and Transcatheter aortic valve implantation (BIT) registry
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Ana Ayesta, Luis Alberto Escobar-Robledo, Manuel Martínez-Sellés, Luis Nombela, Albert Ariza-Solé, Juan José Gómez-Doblas, Eva Bernal, Diego López-Otero, Clara Fernández-Cordón, Antonio Bayés-de-Luna, and Hugo González-Saldívar
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Pacemaker, Artificial ,medicine.medical_specialty ,Transcatheter aortic ,Enfermedad cardiovascular ,Prótesis valvulares cardíacas ,030204 cardiovascular system & hematology ,Transcatheter Aortic Valve Replacement ,Tratamiento médico ,Electrocardiography ,03 medical and health sciences ,QRS complex ,0302 clinical medicine ,Internal medicine ,Enfermos cardíacos ,medicine ,Clinical endpoint ,Humans ,Interatrial Block ,Registries ,030212 general & internal medicine ,Heart valve ,Tecnología médica ,Stroke ,business.industry ,Incidence (epidemiology) ,Aortic Valve Stenosis ,medicine.disease ,Stenosis ,Treatment Outcome ,medicine.anatomical_structure ,Cardiology ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background Aortic stenosis (AS) is currently the most frequent heart valve disease. Symptomatic severe AS has a poor prognosis and transcatheter aortic valve implantation (TAVI) is becoming the therapy of choice in these patients. Changes in the conduction tissue after the procedure constitute one of the main limitations of TAVI, with a frequent need for a definitive pacemaker. Interatrial block (IAB) is defined as a prolonged P-wave duration and is related with atrial fibrosis. The presence of IAB could be a marker of conduction tissue abnormalities at other levels. No study has specifically analyzed the role of IAB as a predictor of the need for permanent pacemaker in patients with AS undergoing TAVI. Methods The Baseline Interatrial block and Transcatheter aortic valve implantation (BIT) registry will be performed in approximately 3000 patients with severe AS treated with TAVI. A centralized analysis of baseline ECGs will study the presence and type of IAB and other ECG data (rhythm, P-wave duration, PR and QRS intervals/intraventricular conduction disorders). Clinical follow-up will be carried out by local researchers. The primary endpoint will be the requirement of permanent pacemaker during post-TAVI hospitalization. As secondary objectives, the incidence of new onset AF, stroke, or mortality during follow-up will be analyzed. Secondary endpoints will include the incidence of new onset AF, stroke, or mortality during follow-up. Conclusion The BIT registry will study, for the first time, the influence of previous IAB in the need of permanent pacemaker after TAVI: This large registry will also provide information regarding the association of this and other ECG parameters with prognosis. Sin financiación 0.944 JCR (2019) Q4, 133/138 Cardiac & Cardiovascular Systems 0.448 SJR (2019) Q3, 205/362 Cardiology and Cardiovascular Medicine No data IDR 2019 UEM
- Published
- 2019
193. 80 The impact of sex and physical performance on long-term mortality in older patients with myocardial infarction
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Elisabetta Tonet, Albert Ariza-solé, Matteo Serenelli, Francesc Formiga, Sanchis Juan, Rita Pavasini, Pablo Diez-villanueva, Francesco Vitali, Clara Bonanad, Giovanni Grazzi, Antoni Carol, Giorgio Chiaranda, Graziella Pompei, Laura Sofia Cardelli, Serena Caglioni, Federico Gibiino, Stefano Volpato, and Gianluca Campo
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Cardiology and Cardiovascular Medicine - Abstract
Aims To investigate the prognostic role of sex and physical performance on long-term mortality in older adults hospitalized for acute coronary syndrome (ACS). Methods and results The analysis is based on older (≥70 years) ACS patients included in the FRASER, HULK, and LONGEVO SCA prospective studies. Physical performance was assessed with the Short Physical Performance Battery (SPPB). The primary outcome was all-cause mortality. The study included 1388 patients, 441 (32%) were women. At presentation, women were older and more compromised than men. After a median follow-up of 998 (730–1168) days, all-cause death occurred in 334 (24.1%) patients. At univariate analysis, female sex was related to increased risk of death. After adjustments for confounding factors, female sex was no longer associated with mortality. Women showed poor physical performance compared with men (P Conclusions Two key findings emerged from the present real-life cohort of older ACS patients: (i) physical performance strongly influences long-term mortality and (ii) women with preserved physical performance have a better outcome compared to men.
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- 2021
194. 80 The impact of sex and physical performance on long-term mortality in older patients with myocardial infarction
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Tonet, Elisabetta, primary, Ariza-solé, Albert, additional, Serenelli, Matteo, additional, Formiga, Francesc, additional, Juan, Sanchis, additional, Pavasini, Rita, additional, Diez-villanueva, Pablo, additional, Vitali, Francesco, additional, Bonanad, Clara, additional, Grazzi, Giovanni, additional, Carol, Antoni, additional, Chiaranda, Giorgio, additional, Pompei, Graziella, additional, Cardelli, Laura Sofia, additional, Caglioni, Serena, additional, Gibiino, Federico, additional, Volpato, Stefano, additional, and Campo, Gianluca, additional
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- 2021
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195. Surprise evaluation of basic life support competencies in health care personnel in the cardiology area of a tertiary hospital
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Castillo García, Jordi, primary, Barrionuevo Sánchez, María Isabel, additional, Sánchez-Salado, José Carlos, additional, Molina Mazón, Carlos-Santos, additional, Arbonés Arqué, Daniel, additional, and Ariza-Solé, Albert, additional
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- 2021
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196. Direct Oral Anticoagulants versus Warfarin in Octogenarians with Nonvalvular Atrial Fibrillation: A Systematic Review and Meta-Analysis
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Bonanad, Clara, primary, García-Blas, Sergio, additional, Torres Llergo, Javier, additional, Fernández-Olmo, Rosa, additional, Díez-Villanueva, Pablo, additional, Ariza-Solé, Albert, additional, Martínez-Sellés, Manuel, additional, Raposeiras, Sergio, additional, Ayesta, Ana, additional, Bertomeu-González, Vicente, additional, Tarazona Santabalbina, Francisco, additional, Facila, Lorenzo, additional, Vivas, David, additional, Gabaldón-Pérez, Ana, additional, Bodi, Vicente, additional, Nuñez, Julio, additional, and Cordero, Alberto, additional
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- 2021
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197. Cardiopatía isquémica y cuidados críticos cardiológicos: un binomio indisoluble
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Jorge, Pablo, primary and Ariza-Solé, Albert, additional
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- 2021
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198. Prognosis Impact of Diabetes in Elderly Women and Men with Non-ST Elevation Acute Coronary Syndrome
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Gonzalo Luis Alonso Salinas, Sergio Raposeiras-Roubín, Alberto Cordero, Francisco Marcos Marín, Pablo Díez-Villanueva, Manuel Martínez-Sellés, Eduardo Núñez, Alfredo Bardají, Albert Ariza-Solé, Nuria Vicente-Ibarra, Juan M. Ruiz-Nodar, Juan Sanchis, Belén Cid-Álvarez, José María García-Acuña, Julio Núñez, Emad Abu Assi, F Formiga, José A. Barrabés, Institut Català de la Salut, [Díez-Villanueva P] Servicio de Cardiología, Hospital Universitario La Princesa, Madrid, Spain. [García-Acuña JM] Servicio de Cardiología, Hospital Clínico Universitario de Santiago, CIBERCV, Santiago de Compostela, A Coruña, Spain. [Raposeiras-Roubin S] Servicio de Cardiología, Hospital Álvaro Cunqueiro de Vigo, Vigo, Pontevedra, Spain. [Barrabés JA] Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. CIBERCV, Barcelona, Spain. [Cordero A] Servicio de Cardiología, Hospital Clínico Universitario de San Juan, Alicante, Spain. [Martínez-Sellés M] Servicio de Cardiología, Hospital Universitario Gregorio Marañón, CIBERCV, Universidad Europea, Universidad Complutense, Madrid, Spain, and Vall d'Hebron Barcelona Hospital Campus
- Subjects
Acute coronary syndrome ,medicine.medical_specialty ,Anemia ,Mujer ,medicine.medical_treatment ,enfermedades nutricionales y metabólicas::enfermedades metabólicas::trastornos del metabolismo de la glucosa::diabetes mellitus [ENFERMEDADES] ,Enfermedad cardiovascular ,Anciano ,Otros calificadores::/diagnóstico [Otros calificadores] ,Dones ,Dietética y nutrición ,Disease ,Malalties coronàries ,Revascularization ,elderly ,Article ,Coronary diseases ,Infarto del miocardio sin elevación del ST ,non-ST-segment elevation acute coronary syndromes ,Diabetes mellitus ,Internal medicine ,Other subheadings::/diagnosis [Other subheadings] ,medicine ,Clinical endpoint ,Endocrinología ,Women ,Diagnosis::Prognosis [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT] ,Diabetis - Prognosi ,diagnóstico::pronóstico [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS] ,Diabetis ,business.industry ,ST elevation ,Diabetes ,General Medicine ,medicine.disease ,Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus [DISEASES] ,Diabetes mellitus tipo 2 ,diabetes mellitus ,Diferències entre sexes ,enfermedades cardiovasculares::enfermedades cardíacas::isquemia miocárdica::síndrome coronario agudo [ENFERMEDADES] ,Medicine ,women ,business ,Cardiovascular Diseases::Heart Diseases::Myocardial Ischemia::Acute Coronary Syndrome [DISEASES] ,Kidney disease - Abstract
Few studies have addressed to date the interaction between sex and diabetes mellitus (DM) in the prognosis of elderly patients with non-ST-segment elevation acute coronary syndrome (NSTEACS). Our aim was to address the role of DM in the prognosis of non-selected elderly patients with NSTEACS according to sex. A retrospective analysis from 11 Spanish NSTEACS registries was conducted, including patients aged ≥70 years. The primary end point was one-year all-cause mortality. A total of 7211 patients were included, 2,770 (38.4%) were women, and 39.9% had DM. Compared with the men, the women were older (79.95 ± 5.75 vs. 78.45 ± 5.43 years, p <, 0.001) and more often had a history of hypertension (77% vs. 83.1%, p <, 0.01). Anemia and chronic kidney disease were both more common in women. On the other hand, they less frequently had a prior history of arteriosclerotic cardiovascular disease or comorbidities such as peripheral artery disease and chronic pulmonary disease. Women showed a worse clinical profile on admission, though an invasive approach and in-hospital revascularization were both more often performed in men (p <, 0.001). At a one-year follow-up, 1090 patients (15%) had died, without a difference between sexes. Male sex was an independent predictor of mortality (HR = 1.15, 95% CI 1.01 to 1.32, p = 0.035), and there was a significant interaction between sex and DM (p = 0.002). DM was strongly associated with mortality in women (HR: 1.45, 95% CI = 1.18–1.78, p <, 0.001), but not in men (HR: 0.98, 95% CI = 0.84–1.14, p = 0.787). In conclusion, DM is associated with mortality in older women with NSTEACS, but not in men.
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- 2021
199. Acute Coronary Syndrome in the Older Patient
- Author
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Manuel Martínez-Sellés, Ana Ayesta, Alberto Cordero, Ana Gabaldon-Perez, Sergio García-Blas, Clara Bonanad, Pablo Díez-Villanueva, Albert Ariza-Solé, Gemma Mateus-Porta, Maria Martinez-Avial, David Escribano, and Vicente Bodi
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medicine.medical_specialty ,Acute coronary syndrome ,Infarto del miocardio con elevación del ST ,Enfermedad cardiovascular ,Anciano ,Review ,Cardiología ,Malalties coronàries ,elderly ,Persones grans ,acute coronary syndrome ,Coronary artery disease ,Older patients ,Infarto del miocardio sin elevación del ST ,Internal medicine ,Medicine ,Síndrome coronario agudo ,Myocardial infarction ,cardiovascular diseases ,Ethical issues ,business.industry ,General Medicine ,medicine.disease ,Clinical Practice ,Coronary heart disease ,myocardial infarction ,Cardiology ,Older people ,business - Abstract
Coronary artery disease is one of the leading causes of morbidity and mortality, and its prevalence increases with age. The growing number of older patients and their differential characteristics make its management a challenge in clinical practice. The aim of this review is to summarize the state-of-the-art in diagnosis and treatment of acute coronary syndromes in this subgroup of patients. This comprises peculiarities of ST-segment elevation myocardial infarction (STEMI) management, updated evidence of non-STEMI therapeutic strategies, individualization of antiplatelet treatment (weighting ischemic and hemorrhagic risks), as well as assessment of geriatric conditions and ethical issues in decision making. Instituto de Salud Carlos III (PI20/00637) Fondos Europeos de Desarrollo Regional FEDER (CIBERCV16/11/00486) 4.964 JCR (2021) Q2, 54/172 Medicine, General & Internal 1.040 SJR (2021) Q1, 438/2489 Medicine (miscellaneous) No data IDR 2020 UEM
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- 2021
200. Considerations on the invasive management of ischemic and structural heart disease during the COVID-19 coronavirus outbreak
- Author
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E. López-De-Sá, A. Ariza-Solé, P. Jorge-Pérez, I. Cruz-González, V. Burgos-Palacios, Rafael Romaguera, Raúl Moreno, A. Jurado-Román, A. Fernández-Cisnal, and Soledad Ojeda
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medicine.medical_specialty ,Heart disease ,medicine.medical_treatment ,Disease ,Internal medicine ,Health care ,Pandemic ,Medicine ,Infection control ,Cardiac catheterization ,Interventional cardiology ,business.industry ,Prevention ,Angioplasty ,COVID-19 ,Outbreak ,medicine.disease ,Interventional Cardiology ,Coronavirus ,Myocardial infarction ,Cardiology ,Infection ,Cardiology and Cardiovascular Medicine ,business - Abstract
The current COVID-19 outbreak is forcing healthcare workers to continuously reconsider the proper indications for cardiac catheterization. Human and material resources optimization, infection prevention for patients and healthcare workers, and transfer times force a rethink of the previously established protocols. This article is a consensus statement of the Interventional Cardiology Association and the Ischemic Heart Disease Association of the Spanish Society of Cardiology and aims to provide information to healthcare workers on the indications of diagnostic or therapeutic cardiac catheterization during the current COVID-19 pandemic. © 2019 Permanyer Publications. All rights reserved.
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- 2021
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