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Las primeras indagaciones en la estructura y composición de la ictiofauna en los ríos de Cuba la realizó el naturalista cubano Felipe Poey. Numerosas han sido las investigaciones realizadas en este campo, principalmente en la región occidental y central de Cuba. Este trabajo se propuso determinar la distribución y similitud de los grupos de especies ícticas dulceacuícolas de las diferentes localidades del municipio Gibara. Se determinó el número de especies por cada localidad, se calculó la similitud a través del índice de Bray-Curtis y el rango de distancia de disimilitud entre las localidades mediante el escalado multidimensional no métrico, el cual permite construir un mapa de ordenamiento del número específico de dimensiones. Se registraron 30 especies, de ellas dos marinas y dos nuevos morfos, que probablemente constituyan especies nuevas. Se agruparon en nueve órdenes, 14 familias y 25 géneros. Las localidades con mayor número de especies fueron las que presentaron una amplia red fluvial tales como, Uñas con 22, Floro Pérez 20, Velasco Uno 19, Cañada de Melones 18, Bocas 17 y Velasco Dos 16. El 30% de las especies son endémicas, con un mayor número en las localidades Velasco Uno, Uña, y Velasco Dos. Las especies exóticas estuvieron presentes en un 18.75%, distribuidas en mayor cantidad en Uñas y Cañada de Melones con seis especies cada una. Las especies autóctonas representaron el 50% del total especies ubicadas principalmente en Floro Pérez, Uña y Velasco Uno. Los resultados del estudio de asociaciones mostraron dos grandes grupos a un 46% de similitud y se obtuvo un nivel de estrés de 0.01 lo que demuestra un buen ajuste del orden espacial y proporción de la distancia ecológica.

Páginas: 216-234., O objetivo deste estudo de caso foi compreender as percepções de estudantes de um programa de ensino de inglês em relação ao papel da reflexão em suas práticas educacionais e investigar a estrutura de reflexão, incluindo os aspectos que os profissionais mais comumente entendem a o tempo para refletir. Para tanto, foram selecionados nove alunos praticantes, e foram analisados seus ensaios reflexivos, reflexões realizadas após a aula e participação em um questionário virtual. Os resultados mostraram que os estudantes praticantes perceberam a reflexão como um elemento fundamental e indispensável para encontrar soluções para aspectos negativos de suas aulas. Embora os profissionais apontassem como uma de suas motivações para refletir o fato de ser um exercício obrigatório no tema, eles também reconheceram a importância do mesmo como elemento fundamental para o desenvolvimento do ensino profissional. O esquema mais comum seguido pelos estudantes em suas reflexões foi a descrição dos eventos de classe como um passo preliminar para a reflexão. Em conclusão, foi estabelecido que os alunos ainda estão em um nível básico de reflexão, o que levou o programa de prática a trabalhar mais neste componente., El presente estudio de caso tuvo como propósito conocer las percepciones de los estudiantes de un programa de enseñanza de inglés frente al rol de la reflexión en sus prácticas educativas e indagar sobre la estructura de la reflexión, incluyendo los aspectos que los practicantes más comúnmente comprenden a la hora de reflexionar. Para este propósito, fueron seleccionados nueve estudiantes practicantes, a los que se les analizaron ensayos reflexivos, reflexiones realizadas después de clase y la participación en un cuestionario virtual. Los resultados demostraron que los estudiantes practicantes percibieron la reflexión como un elemento fundamental e indispensable para encontrar soluciones frente a aspectos negativos de sus clases. Si bien los practicantes señalaron como una de sus motivaciones para reflexionar el hecho de ser un ejercicio obligatorio en la asignatura, también reconocieron la importancia de la misma como un elemento fundamental para su desarrollo profesional docente. El esquema más común seguido por los estudiantes en sus reflexiones fue la descripción de eventos de clase como paso previo a la reflexión. Como conclusión, se pudo establecer que los estudiantes aún se encuentran en un nivel básico de reflexión, lo que impulsó al programa de práctica a trabajar más sobre este componente., The purpose of this case study was to understand the perceptions of students of an English teaching program in the face of the role of reflection in their educational practices and to investigate the structure of reflection, including the aspects that practitioners most commonly understood when they reflected. For this purpose, nine practicing students were selected, who were analyzed reflective essays, reflections made after class and participation in a virtual questionnaire. The results showed that the practicing students perceived the reflection as a fundamental and indispensable element to find solutions to negative aspects of their classes. Although the practitioners pointed out as one of their motivations to reflect the fact of being a mandatory exercise in the subject, they also recognized the importance of it as an overriding element for their professional teaching development. The most common scheme followed by students in their reflections was the description of class events as a preliminary step to reflection. In conclusion, it was established that the students are still at a basic level of reflection, which prompted the practice program to work more on this component., Bibliografía: páginas 231-234., Artículo de investigación revisado por pares académicos.

The perception of job insecurity is a frequent and increasing phenomenon in the current social and economic context. The availability of reliable and valid metrics to measure this phenomenon is of paramount importance. In the present paper, we suggest a modification to the Chirumbolo et al.’s (2015) job insecurity scale, revising an item from the Italian version. A questionnaire was submitted to 315 Italian employees. One hundred and fifty-seven employees filled in the original scale and one hundred and fifty-eight employees filled in the modified scale with the proposed revision. Both a confirmatory and exploratory factorial analysis showed that the modified item better describes worries and concerns related to job insecurity. Moreover, the modified scale’s reliability improves compared to the original one., Rassegna di Psicologia, Vol 33, No 1 (2016)

This chapter presents the study case of the integration of noninvasive in situ investigation methods able to provide information useful to survey and characterize the state of decay of some masonry walls and frescoes in two blocks (insulae) of the Regio VIII in Pompeii. The integrated investigations demonstrated the complementarity of ground-penetrating radar (GPR), seismic tomography, and infrared thermography (IRT) for the diagnosis of the state of conservation and the restoration of structures and surfaces of archaeological monuments. The investigation was very useful in planning the restoration work.

Multicystic mesothelioma (MM) is a relatively rare tumour arising in the pelvic peritoneum of the tuboovarian region of young woman. Exceptionally, MM occurs on the serosal surfaces of various organs including kidney, bladder, lymph nodes, and liver. We report here the first case of MM wherein a 58-year-old woman with a previous history of endometriosis of the right ovary presented with a large multicystic mass of the spleen. The diagnosis of MM was made on a surgical specimen after splenectomy. A histopathologic examination is always necessary for the diagnosis of MM which should be differentiated from other lesions particularly from cystic lymphangioma. At one year follow-up, the patient had no evidence of recurrence. Despite the high frequency of local recurrences, MM is a benign lesion and ‘en bloc’ surgical excision with prolonged follow-ups is the treatment of choice.

Los maíces pigmentados contienen una gran cantidad de antocianinas las cuales le proveen de diversas tonalidades y características nutracéuticas. Se ha demostrado que el consumo de frutas y verduras que contienen antocianinas traen efectos benéficos en la salud y prevención de enfermedades crónico-degenerativas. Por la gran riqueza que representan el consumo de maíces pigmentados en especial el maíz VC-42 se investigó sus posibles beneficios en la prevención y tratamiento en contra del crecimiento anormal de células (tumores). Con el objetivo de extraer y caracterizar las moléculas de antocianinas en los granos de maíz azul VC-42 se empleó una mezcla de EtOH: H3O+ (HCl 1 M, 0.1 %), 70:30, la separación se realizó mediante cromatografía de columna preparada (C18), la caracterización se realizó mediante espectroscopia UV-Vis, IR y TOF-MS. La evaluación antitumoral se realizó empleando modelos celulares con crecimiento anormal inducido probando con ello su capacidad antitumoral en líneas de cáncer cérvico uterino y de mama (CaCu y CM). Los extractos eluidos mediante columnas C18 mostraron espectros UV-Vis, IR y TOF-Masas características de las antocianinas. Las antocianinas presentes en el extracto inhiben la proliferación celular de las líneas HeLa, SiHa y MCF-7 en un 18.5, 34 y 35 % respectivamente a una concentración de 150 ?g/ml. Las antocianinas presentes en el maíz VC-42 al ser compuestos antioxidantes pueden prevenir y tratar padecimientos relacionados con el cáncer CaCu y CM. El maíz azul VC-42 es un alimento nutracéutico ya que el contenido de antocianinas proveen de un beneficio a la salud.

Background: We describe 2 cases of vulvar pseudotumour due to lymphatic obstruction with chronic lymphoedema of unknown cause that presented as a solitary mass that mimicked aggressive angiomyxoma. Material and Methods: Both patients presented with a vulvar mass without medical history of trauma, surgery in the anogenital region or skin diseases. One patient was overweight (BMI = 26). Both surgically resected vulvar specimens were represented by a polypoid mass with a soft and a gelatinous cut surface. Results: Histologically, the presence of an abundant oedematous stroma with spindle-shaped cells and numerous thin-walled small-to-medium vessels may be confused with an aggressive angiomyxoma. The diagnostic key was represented by the massive oedema, rather than myxoid stroma, with the presence of dilated, tortuous lymphatic channels (some surrounded by clusters of lymphocytes) in the dermis. Conclusion: The recognition of these lesions is important because they may be the cause of problems in differential diagnosis and therapeutic management. In fact, such lesions can be mistaken from both the clinical and histological perspective as a primitive tumour of the vulva-like aggressive angiomyxoma. However, these lesions are not true neoplasms and are likely due to lymphatic obstruction with lymphoedema. A simple surgical excision with vulvoplasty is curative.

En el presente artículo se ofrecen resultados de una investigación sobre construcción deconocimiento. En particular estamos interesados en el estudio de los procesos presentes en laarticulación de los sistemas conceptuales matemáticos a los que hemos llamado procesos deconvención y articulación matemática (Martínez-Sierra, 2005). De manera específica este trabajoindaga sobre qué alternativas pueden ser factibles para la construcción escolar del significado de losnúmeros complejos, bajo la hipótesis de que su significado puede ser construido a través delproceso de convención matemática. El análisis de la producción de los estudiantes, al trabajar unasecuencia de actividades diseñada por nosotros en base a la hipótesis anterior, da evidencia de que apesar que los estudiantes insistían en que "las raíces cuadradas de números negativos no existen",nuestra secuencia los indujo a operar con ellos y de esta manera construir un significado en el planooperativo.

Summary This paper presents a new method to deal with uncertainty mitigation by using observed data, integrating the uncertainty analysis and the history-matching processes. The proposed methods are robust and easy to use, and offer an alternative to traditional history-matching methods. The main characteristic of the method is the use of observed data as constraints to reduce the uncertainty of the reservoir parameters. The main objective is the integration of uncertainty analysis with history matching, providing a natural manner to make predictions under reduced uncertainty. Three methods are proposed: (1) probability redistribution, (2) elimination of attribute levels, and (3) redefinition of attribute values. To test the results of the proposed approach, we investigated three reservoir examples. The first one is a synthetic and simple case; the second one is a synthetic but realistic case; and the third one is a real reservoir from the Campos basin of Brazil. The results presented in the paper show that it is possible to conduct an integrated study of uncertainty analysis and history matching. The main contribution of this work is to present a practical way to increase the reliability of prediction through reservoir-simulation models that incorporate uncertainty analysis in the history period and provide reliable reservoir-simulation models for prediction forecast.

Objectives: Meningiomas are slow-growing intracranial/intraspinal tumors, with a wide range of histopathologic variants. The more aggressive atypical and malignant types can disseminate via the venous system, lymphatic, system, or cerebrospinal fluid, with the lung and pleura being the most common sites of extracranial metastases. A case of metastatic meningioma with high expression of CD90 was spotted during a review of flow cytometry data for lung malignancies. Therefore, we have analyzed CD90 expression in a series of meningioma metastases with their corresponding primary tumors and in a series of 92 primary meningioma tumors. Methods: In addition to flow cytometry and immunohistochemical analysis of the case, a series of meningiomas and relative metastases has been evaluated for CD90 immunohistochemical expression. Furthermore, an immunohistochemical analysis has been conducted in a tissue microarray, including typical and atypical meningiomas. Results: CD90 had high expression in three of four cases of metastases and in their corresponding primary atypical meningioma. In addition, CD90 was significantly expressed in atypical rather than in typical meningiomas ( P = .003). However, the correlation of CD90 with patient survival reveals only a trend of statistical association with extracranial metastases. Conclusions: CD90 is a biomarker overexpressed in atypical meningioma, with a potential role in metastatic switch of this tumor.

Neuroendocrine features are detectable in carcinomas of the breast either as scattered cells, that are recognized by their expression of neuroendocrine cell markers. Instead, pure breast carcinomas with neuroendocrine features (NEBC) are very rare and represent

Figure S1: Gene ontology classification of C. brasiliense unigenes. Figure S2: Biological processes assigned to differentially expressed genes. Figure S3: Re-constructed C. brasiliense metabolic network from glucose to trans-cinnamate. Figure S4: Phylogenetic relationships, primary protein structures and identities percent of trans-cinnamate 4-hydroxylases proteins. Figure S5: Structural and phylogenetic analysis of 4-coumarate: CoA ligases (4CL) from C. brasiliense. Figure S6: Alignment of the 4-coumaroyl 2′-hydroxylases from C. brasiliense. Figure S7: Schematic representation of the Wagner-Meerwein rearrangement. Figure S8: C. brasiliense prenyltransferases. Figure S9: Phylogenetic tree of selected C. brasiliense cytochrome P450. (PPTX 1219 kb)

We report a case of malignant mesothelioma of the spermatic cord in 80-year-old man presented with retained testis, hydrocele, and right inguinal mass. The patient had a long history of asbestos exposure as a railway worker. The patient was submitted to inguinal radical orchiectomy. One year after surgery, the patient is alive without signs of disease. Malignant mesothelioma of spermatic cord is a very rare disease, but this diagnosis should be suspected in patient with a history of asbestos exposure.

We describe a case of an unusual lymphoproliferative disease in a 60-year-old man. He presented at Hospital “Cardarelli” in March 2004 with fever, fatigue and weight loss. Physical examination and ...

Background: The association between lymphomas and Kaposi’s sarcoma has been described since 1920. The simultaneous presence of the 2 pathologic entities within the same lymph node is a rare and interesting occurrence. In the few cases described, the presence of human herpesvirus 8 (HHV8) and Epstein-Barr virus (EBV) in the different neoplastic areas was investigated only by immunohistochemistry and in situ hybridization studies. Methods: Two cases of concurrent non-Hodgkin lymphoma and Kaposi’s sarcoma in the same lymph node are described: a diffuse large B cell lymphoma in an AIDS patient and a T cell-rich large B cell lymphoma in a HIV-negative patient, complete with the clinical, immunohistological and molecular features, the latter ones defined after isolation of the different neoplastic areas by laser capture microdissection. Results: Polymerase chain reaction assays revealed HHV8 DNA sequences only in the microdissected Kaposi’s sarcoma areas and EBV DNA sequences only in the lymphomatous areas in both cases, confirming the HHV8 infection only in the neoplastic sarcomatous cells and evidencing the EBV infection only in the lymphomatous cells. Conclusion: This study represents a further confirmation of the supposed different etiopathogenic mechanisms of the 2 neoplasias, suggesting a coincidental occurrence even when localized in the same lymph node, independently from HIV infection.

Plasmablastic lymphoma is a rare, highly aggressive lymphoma characterized by large lymphoid cells with immunoblastic or plasmablastic features, absent expression of CD45 and CD20, positivity for CD138, and monoclonal rearrangement of the immunoglobulin heavy chain gene. It was originally reported in oral cavity in the setting of underlying human immunodeficiency viral infection but may occur also in lymph nodes or extranodal sites after transplantation and, more rarely, immunocompetent patients. Herein, we report a case of PBL presenting as an ulcerated lesion of the tongue in an HIV-negative patient, 6 years after renal transplantation. To date, only rare cases of plasmablastic lymphoma presenting after solid organ transplantation have been reported. Although a reduction of immunosuppression and an aggressive chemotherapy were performed, the patient died after a few months because of septic and cardiovascular complications.

Primary breast mucosa-associated lymphoid tissue (MALT) lymphomas are uncommon and restricted diagnostic criteria should be used to exclude breast involvement by systemic lymphomas. The molecular pathogenesis of primary breast MALT lymphomas is not clear because of the rarity of the disease. Generally the molecular studies of MALT lymphoma in extranodal sites have shown the presence of different chromosomal aberrations, mutually exclusive with substantial differences in their frequency relatively to topographic localization. Few cases of breast MALT lymphomas in the literature have been assessed for MALT lymphoma-associated translocations and BCL10 expression, underlying their rarity in primary breast MALT lymphomas. In our study, we analyzed a series of nine cases of primary breast MALT lymphomas. FISH results showed evidence of MALT1 gene rearrangements in four primary breast lymphomas, in particular three cases with t(11;18)(q21;q21) and one case with t(14;18)(q32;q21). In addition, BCL10 gene rearrangement was not observed. There was no evidence of BCL10 gene translocation in any of the neoplasms assessed. Our data indicate that MALT1 gene rearrangements are not rare in primary breast MALT lymphoma in contrast with results of previous series. Finally, t(11;18) has been observed to be significantly associated with high intensity cytoplasmic BCL10 expression underlying cross-talk between MALT1 and BCL10 pathways in the pathogenesis of MALT lymphomas.

Endodermal cysts of the central neuraxis are benign, non-neoplastic epithelium-lined cysts arising from endodermal tissue that have been displaced early in fetal life. Intracranial endodermal cysts are rare and usually located in the posterior fossa. The present study involves a 36-year-old man with a typical epithelial cyst in the posterior fossa. Microscopically, the cyst has a simple columnar epithelium with mucus-producing cells, containing an area composed of dysplastic epithelium with evidence of an intraepithelial carcinoma. The atypical cells have a high proliferative fraction demonstrated by Ki-67 immunostain. Based on these findings, the authors view this case as evidence of a malignant transformation of a classic endodermal cyst. The clinicopathologic features and a review of the literature are discussed.

El objetivo fundamental del trabajo que se presenta es la propuesta de herramientas i formáticas de simulación y post-proceso de plantas termosolares de torre que, derivando de las técnicas ray-tracing aporten, sin merma apreciable de la precisión, una reducción de los tiempos de ejecución, pues se trata de uno de los principales inconvenientes del método. En primer lugar se exponen las hipótesis de partida de los códigos desarrollados. Se continuará realizando un acercamiento a los errores ópticos involucrados en los problemas de simulación. Posteriormente se exponen los esquemas de operación de los códigos presentados. Finalmente se llevará a cabo un estudio de los tiempos de ejecución y de precisión. En el presente documento se presentarán dos códigos de simulación de plantas termosolares de torre con receptor de cavidad. Ambos se han desarrollado en lenguaje de programación propio de MATLAB. El primero de los cuales se considera un código ray-tracing convencional (código RT), optimizado para cálculo paralelo y basado en la proyección de un solo rayo incidente encada punto de cálculo elegido sobre la superficie reflectante del heliostato. Sus prestaciones y resultados se emplearán como modelo de referencia. El segundo código presentado (código RT-HR) considera que en un mismo punto de la superficie reflectante del heliostato se aplican más de un rayo incidente. Los autores desean agradecer al Ministerio de Economía y Competitividad la financiación proporcionada al trabajo, a través de los proyectos de Plan nacional de I+D+i ENE2012-37950-C02- 01 y ENE2012-37950-C02-02.